Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Nr2c1

Z-value: 0.81

Motif logo

logo of

Transcription factors associated with Nr2c1

Gene Symbol Gene ID Gene Info
Nr2c1
ENSRNOG00000006983 nuclear receptor subfamily 2, group C, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2c1rn6_v1_chr7_+_35070284_35070284-0.351.7e-10Click!

Activity profile of Nr2c1 motif

Sorted Z-values of Nr2c1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_11240138 47.39 ENSRNOT00000048687
Srl
sarcalumenin
chr6_+_137184820 39.54 ENSRNOT00000073796
Adssl1
adenylosuccinate synthase like 1
chr19_-_56677084 34.54 ENSRNOT00000024084
Acta1
actin, alpha 1, skeletal muscle
chr8_-_84506328 28.27 ENSRNOT00000064754
Mlip
muscular LMNA-interacting protein
chr5_-_57372239 25.28 ENSRNOT00000012975
Aqp7
aquaporin 7
chr1_-_221917901 24.36 ENSRNOT00000092270
Slc22a12
solute carrier family 22 member 12
chr9_-_115850634 23.90 ENSRNOT00000049720
Lrrc30
leucine rich repeat containing 30
chr10_+_86337728 23.64 ENSRNOT00000085408
Tcap
titin-cap
chr10_+_71159869 20.82 ENSRNOT00000075977
ENSRNOT00000047427
Hnf1b
HNF1 homeobox B
chr9_+_65478496 20.82 ENSRNOT00000016060
Ndufb3
NADH:ubiquinone oxidoreductase subunit B3
chr2_+_233615739 19.09 ENSRNOT00000051009
Pitx2
paired-like homeodomain 2
chr6_+_8284878 16.97 ENSRNOT00000009581
Slc3a1
solute carrier family 3 member 1
chr1_+_31264755 16.11 ENSRNOT00000028988
LOC679739
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr5_-_101138427 14.04 ENSRNOT00000058615
Frem1
Fras1 related extracellular matrix 1
chr5_+_173640780 13.83 ENSRNOT00000027476
Perm1
PPARGC1 and ESRR induced regulator, muscle 1
chr1_-_222178725 12.40 ENSRNOT00000028697
Esrra
estrogen related receptor, alpha
chr1_+_101517714 12.38 ENSRNOT00000028423
Plekha4
pleckstrin homology domain containing A4
chr10_-_50574539 12.35 ENSRNOT00000034261
Cox10
COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
chr4_+_102426224 11.87 ENSRNOT00000073768
LOC103694107
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 pseudogene
chr8_-_55087832 11.78 ENSRNOT00000032152
Dlat
dihydrolipoamide S-acetyltransferase
chr7_-_117267803 11.33 ENSRNOT00000082271
Plec
plectin
chr14_-_83741969 10.89 ENSRNOT00000026293
Inpp5j
inositol polyphosphate-5-phosphatase J
chr7_-_117268300 10.39 ENSRNOT00000091840
Plec
plectin
chr1_+_175586097 10.09 ENSRNOT00000024933
Ampd3
adenosine monophosphate deaminase 3
chr7_-_144272578 9.82 ENSRNOT00000020676
Atp5g2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr3_-_48536235 9.11 ENSRNOT00000083536
Fap
fibroblast activation protein, alpha
chr9_+_65763437 8.88 ENSRNOT00000043558
Stradb
STE20-related kinase adaptor beta
chr2_+_198965685 8.82 ENSRNOT00000000107
ENSRNOT00000091578
Pdzk1
PDZ domain containing 1
chr9_-_9985630 8.54 ENSRNOT00000071780
Crb3
crumbs 3, cell polarity complex component
chr19_-_55284663 8.51 ENSRNOT00000018387
Snai3
snail family transcriptional repressor 3
chr14_-_17582823 8.41 ENSRNOT00000087686
LOC100911949
uncharacterized LOC100911949
chr1_-_141579871 8.00 ENSRNOT00000020002
Anpep
alanyl aminopeptidase, membrane
chr1_+_222519615 7.81 ENSRNOT00000083585
Rcor2
REST corepressor 2
chr2_+_95045034 7.52 ENSRNOT00000081305
Mrps28
mitochondrial ribosomal protein S28
chr15_+_108960562 7.41 ENSRNOT00000081906
ENSRNOT00000077482
Pcca
propionyl-CoA carboxylase alpha subunit
chr9_-_65763273 7.38 ENSRNOT00000015034
Trak2
trafficking kinesin protein 2
chr15_+_19603288 7.18 ENSRNOT00000035491
LOC102552640
REST corepressor 2-like
chr7_+_120380544 6.74 ENSRNOT00000015009
Polr2f
RNA polymerase II subunit F
chr6_-_106971250 6.63 ENSRNOT00000010926
Dpf3
double PHD fingers 3
chr2_-_178389608 6.23 ENSRNOT00000013262
Etfdh
electron transfer flavoprotein dehydrogenase
chr9_+_17105151 5.90 ENSRNOT00000091113
Tjap1
tight junction associated protein 1
chr20_+_27954433 5.48 ENSRNOT00000064288
Lims1
LIM zinc finger domain containing 1
chr5_-_58476251 5.24 ENSRNOT00000013151
Stoml2
stomatin like 2
chr1_+_212558257 4.16 ENSRNOT00000024912
Prap1
proline-rich acidic protein 1
chr12_+_47407811 3.86 ENSRNOT00000001565
Hnf1a
HNF1 homeobox A
chr7_-_127081704 3.76 ENSRNOT00000055893
LOC108351584
uncharacterized LOC108351584
chr6_-_21135880 3.65 ENSRNOT00000051239
Rasgrp3
RAS guanyl releasing protein 3
chr20_-_3819200 3.60 ENSRNOT00000000542
ENSRNOT00000081486
Hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
chr8_+_127171537 3.24 ENSRNOT00000078625
ENSRNOT00000051290
ENSRNOT00000087753
Golga4
golgin A4
chr11_-_61530830 3.05 ENSRNOT00000059666
ENSRNOT00000068345
Naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr8_-_43920420 2.77 ENSRNOT00000081179
Olr1339
olfactory receptor 1339
chr3_+_37545238 2.74 ENSRNOT00000070792
Tnfaip6
TNF alpha induced protein 6
chr2_+_148722231 2.45 ENSRNOT00000018022
Eif2a
eukaryotic translation initiation factor 2A
chr3_-_148428494 2.29 ENSRNOT00000011350
Dusp15
dual specificity phosphatase 15
chr7_-_120380200 2.08 ENSRNOT00000014878
RGD1359634
similar to RIKEN cDNA 1700088E04
chr12_-_29952196 1.86 ENSRNOT00000086175
Tmem248
transmembrane protein 248
chr10_-_87541851 1.77 ENSRNOT00000089610
RGD1561684
similar to keratin associated protein 2-4
chr13_-_109770199 1.39 ENSRNOT00000043672
Fam71a
family with sequence similarity 71, member A
chr15_-_28446785 1.21 ENSRNOT00000015439
Olr1638
olfactory receptor 1638
chr3_-_148428288 1.18 ENSRNOT00000072663
Dusp15
dual specificity phosphatase 15
chr3_+_97723901 1.12 ENSRNOT00000080416
Mpped2
metallophosphoesterase domain containing 2
chr12_+_6283288 1.11 ENSRNOT00000001203
Wdr95
WD40 repeat domain 95
chr1_+_85162452 1.07 ENSRNOT00000093347
Pak4
p21 (RAC1) activated kinase 4
chr4_+_157181795 1.02 ENSRNOT00000017090
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr10_-_75202030 0.73 ENSRNOT00000050349
Olr1522
olfactory receptor 1522
chr10_+_4411766 0.71 ENSRNOT00000003213
LOC100911685
eukaryotic peptide chain release factor GTP-binding subunit ERF3B-like
chr15_+_38069320 0.61 ENSRNOT00000014397
Sap18
Sin3-associated polypeptide 18
chr10_+_4313100 0.28 ENSRNOT00000074487
LOC100911685
eukaryotic peptide chain release factor GTP-binding subunit ERF3B-like
chr11_-_84037938 0.27 ENSRNOT00000002327
Abcf3
ATP binding cassette subfamily F member 3
chr13_+_99004942 0.21 ENSRNOT00000085390
Acbd3
acyl-CoA binding domain containing 3
chr19_+_22569999 0.03 ENSRNOT00000022573
Dnaja2
DnaJ heat shock protein family (Hsp40) member A2

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2c1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.5 58.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
13.2 39.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
11.8 47.4 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
6.9 20.8 GO:0061215 mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
6.4 19.1 GO:0021539 subthalamus development(GO:0021539) pulmonary vein morphogenesis(GO:0060577)
5.1 25.3 GO:0015793 glycerol transport(GO:0015793)
3.9 3.9 GO:0035565 regulation of pronephros size(GO:0035565)
3.0 9.1 GO:0097325 melanocyte proliferation(GO:0097325)
2.5 7.4 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
2.2 24.4 GO:0015747 urate transport(GO:0015747)
2.2 8.8 GO:0015879 carnitine transport(GO:0015879)
1.7 10.1 GO:0032264 IMP salvage(GO:0032264)
1.3 5.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
1.1 21.7 GO:0031581 hemidesmosome assembly(GO:0031581)
1.0 28.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.8 11.8 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.7 12.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.7 5.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.7 8.0 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.6 10.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.6 14.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.6 6.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.6 13.8 GO:0014850 response to muscle activity(GO:0014850)
0.4 2.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.4 3.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 9.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 12.4 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.3 3.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.3 20.8 GO:0022900 electron transport chain(GO:0022900)
0.2 3.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 8.9 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 6.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 17.0 GO:0006865 amino acid transport(GO:0006865)
0.1 2.7 GO:0030728 ovulation(GO:0030728)
0.0 4.3 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 3.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 1.0 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.0 11.0 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 34.5 GO:0005865 striated muscle thin filament(GO:0005865)
1.3 9.1 GO:0071438 invadopodium membrane(GO:0071438)
1.2 11.8 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
1.1 21.7 GO:0030056 hemidesmosome(GO:0030056)
1.1 16.1 GO:0070469 respiratory chain(GO:0070469)
0.8 75.4 GO:0031526 brush border membrane(GO:0031526)
0.8 9.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.6 8.0 GO:0031983 vesicle lumen(GO:0031983)
0.6 6.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 6.6 GO:0071565 nBAF complex(GO:0071565)
0.4 3.1 GO:0031415 NatA complex(GO:0031415)
0.4 20.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4 12.3 GO:0070069 cytochrome complex(GO:0070069)
0.3 5.2 GO:0042101 T cell receptor complex(GO:0042101)
0.3 2.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 7.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 3.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 7.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 6.2 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 10.9 GO:0045171 intercellular bridge(GO:0045171)
0.2 0.6 GO:0061574 ASAP complex(GO:0061574)
0.2 20.8 GO:0016605 PML body(GO:0016605)
0.2 8.9 GO:0016235 aggresome(GO:0016235)
0.2 64.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 23.6 GO:0030018 Z disc(GO:0030018)
0.1 10.9 GO:0043198 dendritic shaft(GO:0043198)
0.1 14.0 GO:0005604 basement membrane(GO:0005604)
0.0 5.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.0 11.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.8 GO:0045095 keratin filament(GO:0045095)
0.0 6.6 GO:0005911 cell-cell junction(GO:0005911)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 25.3 GO:0015254 glycerol channel activity(GO:0015254)
4.7 23.6 GO:0051373 FATZ binding(GO:0051373)
3.6 10.9 GO:0052743 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) inositol tetrakisphosphate phosphatase activity(GO:0052743)
2.5 10.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
2.4 24.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.5 12.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
1.5 11.8 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
1.2 3.6 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
1.0 6.2 GO:0048039 ubiquinone binding(GO:0048039)
0.9 7.4 GO:0016421 CoA carboxylase activity(GO:0016421)
0.9 9.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.8 6.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.7 5.2 GO:1901612 cardiolipin binding(GO:1901612)
0.7 39.5 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.6 21.7 GO:0030506 ankyrin binding(GO:0030506)
0.5 9.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 7.4 GO:0050811 GABA receptor binding(GO:0050811)
0.4 19.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 8.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 25.9 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.3 1.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 3.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 20.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 15.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 45.7 GO:0005525 GTP binding(GO:0005525)
0.1 3.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 4.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 10.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 3.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 8.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 7.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.4 GO:0000049 tRNA binding(GO:0000049)
0.0 5.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 17.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 3.7 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 34.5 PID RHOA PATHWAY RhoA signaling pathway
0.6 19.1 ST GAQ PATHWAY G alpha q Pathway
0.5 24.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.9 PID LKB1 PATHWAY LKB1 signaling events
0.1 5.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 14.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 39.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
2.2 24.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
2.1 25.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.8 11.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.6 18.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6 24.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.6 10.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.6 23.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.6 8.9 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.5 7.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4 6.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.4 17.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 27.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 5.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 10.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 7.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 12.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 3.7 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)