Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Nr2e1

Z-value: 0.67

Motif logo

logo of

Transcription factors associated with Nr2e1

Gene Symbol Gene ID Gene Info
Nr2e1
ENSRNOG00000050550 nuclear receptor subfamily 2, group E, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2e1rn6_v1_chr20_-_47306318_47306318-0.344.9e-10Click!

Activity profile of Nr2e1 motif

Sorted Z-values of Nr2e1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_176381477 42.67 ENSRNOT00000048367
Slco1a6
solute carrier organic anion transporter family, member 1a6
chr4_-_176294997 35.69 ENSRNOT00000015112
ENSRNOT00000051461
ENSRNOT00000000026
ENSRNOT00000039877
ENSRNOT00000049303
Slc21a4
kidney specific organic anion transporter
chr17_-_43543172 30.20 ENSRNOT00000080684
ENSRNOT00000029626
ENSRNOT00000082719
Slc17a3
solute carrier family 17 member 3
chr3_-_63568464 27.32 ENSRNOT00000068494
AABR07052585.2

chr8_-_62948720 19.83 ENSRNOT00000075476
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr2_+_222214885 16.29 ENSRNOT00000055723
Dpyd
dihydropyrimidine dehydrogenase
chr7_+_71572941 15.73 ENSRNOT00000007255
Sdc2
syndecan 2
chr5_-_77492013 14.87 ENSRNOT00000012293
LOC259245
alpha-2u globulin PGCL5
chr5_-_52767592 14.03 ENSRNOT00000048383
LOC298111
alpha2u globulin
chr2_+_198655437 13.57 ENSRNOT00000028781
Hfe2
hemochromatosis type 2 (juvenile)
chr8_+_103459161 12.94 ENSRNOT00000074047
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr2_-_210703606 12.82 ENSRNOT00000077563
Gstm6l
glutathione S-transferase, mu 6-like
chr2_+_153803349 11.95 ENSRNOT00000088565
Mme
membrane metallo-endopeptidase
chr2_-_210703265 11.75 ENSRNOT00000080228
Gstm6l
glutathione S-transferase, mu 6-like
chr1_+_13595295 10.40 ENSRNOT00000079250
Nhsl1
NHS-like 1
chr5_-_79874671 9.08 ENSRNOT00000084563
Tnc
tenascin C
chr16_+_2706428 8.83 ENSRNOT00000077117
Il17rd
interleukin 17 receptor D
chr18_-_64061472 7.57 ENSRNOT00000022519
Fam210a
family with sequence similarity 210, member A
chr1_+_152072665 7.55 ENSRNOT00000022538
Rab38
RAB38, member RAS oncogene family
chr4_+_32541706 7.34 ENSRNOT00000050827
Sdhaf3
succinate dehydrogenase complex assembly factor 3
chr10_-_59883839 7.21 ENSRNOT00000093579
Aspa
aspartoacylase
chr5_+_43603043 6.82 ENSRNOT00000009899
Epha7
Eph receptor A7
chr13_+_89755845 5.60 ENSRNOT00000005550
Nectin4
nectin cell adhesion molecule 4
chr8_-_22821397 5.52 ENSRNOT00000045488
Kank2
KN motif and ankyrin repeat domains 2
chr1_+_203509731 5.48 ENSRNOT00000028007
Hmx3
H6 family homeobox 3
chr17_-_89923423 4.36 ENSRNOT00000076964
Acbd5
acyl-CoA binding domain containing 5
chr10_+_55555089 4.32 ENSRNOT00000006597
Slc25a35
solute carrier family 25, member 35
chr9_+_30939555 4.29 ENSRNOT00000016887
Lmbrd1
LMBR1 domain containing 1
chr2_-_192960294 3.56 ENSRNOT00000012420
LOC102552326
late cornified envelope protein 5A-like
chr9_+_118332517 3.19 ENSRNOT00000031943
LOC103690198
taste receptor type 2 member 143
chr14_-_107160334 3.17 ENSRNOT00000012131
Ehbp1
EH domain binding protein 1
chr14_+_104191517 3.12 ENSRNOT00000006573
Spred2
sprouty-related, EVH1 domain containing 2
chrX_-_106116886 3.01 ENSRNOT00000052009
Tcp11x2
t-complex 11 family, X-linked 2
chr5_-_138462864 2.69 ENSRNOT00000011325
Ccdc30
coiled-coil domain containing 30
chr3_+_37146955 2.48 ENSRNOT00000030442
Tas2r134
taste receptor, type 2, member 134
chr4_+_71790701 2.20 ENSRNOT00000085902
Tas2r143
taste receptor, type 2, member 143
chr8_+_117812099 1.72 ENSRNOT00000077228
Ccdc51
coiled-coil domain containing 51
chr20_-_32628953 1.68 ENSRNOT00000000451
Gprc6a
G protein-coupled receptor, class C, group 6, member A
chr1_+_167758636 1.58 ENSRNOT00000024957
Olr46
olfactory receptor 46
chr4_+_72332490 1.54 ENSRNOT00000088294
LOC103692138
olfactory receptor 6B1
chr18_-_72649915 1.28 ENSRNOT00000072205
AABR07032582.1

chr1_-_63457134 1.23 ENSRNOT00000083436
AABR07071874.1

chr1_+_230011125 1.09 ENSRNOT00000087890
Olr352
olfactory receptor 352
chr1_-_168160811 1.03 ENSRNOT00000020981
Olr70
olfactory receptor 70
chr12_+_27155587 0.72 ENSRNOT00000044800
AABR07035916.1

chr5_-_12199283 0.56 ENSRNOT00000007769
Pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr1_-_7335936 0.51 ENSRNOT00000020453
Ltv1
LTV1 ribosome biogenesis factor
chr17_+_63635086 0.08 ENSRNOT00000020634
Dip2c
disco-interacting protein 2 homolog C

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2e1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 35.7 GO:0051958 methotrexate transport(GO:0051958)
5.4 16.3 GO:0006214 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
3.0 12.0 GO:0071492 cellular response to UV-A(GO:0071492)
2.7 30.2 GO:0015747 urate transport(GO:0015747)
2.3 9.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.9 7.5 GO:0060155 platelet dense granule organization(GO:0060155)
1.8 5.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.5 7.3 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
1.2 42.7 GO:0042168 heme metabolic process(GO:0042168)
1.1 6.8 GO:0051964 negative regulation of synapse assembly(GO:0051964)
1.1 4.4 GO:0030242 pexophagy(GO:0030242)
0.9 13.6 GO:0016540 protein autoprocessing(GO:0016540)
0.4 15.7 GO:0031000 response to caffeine(GO:0031000)
0.4 7.2 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.2 4.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.2 3.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 5.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 5.4 GO:0050909 sensory perception of taste(GO:0050909)
0.1 3.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 5.5 GO:0007566 embryo implantation(GO:0007566)
0.1 12.9 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.1 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 8.8 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 19.8 GO:0007155 cell adhesion(GO:0007155)
0.0 4.3 GO:0006839 mitochondrial transport(GO:0006839)
0.0 1.7 GO:0019722 calcium-mediated signaling(GO:0019722)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 13.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
1.3 7.5 GO:0031904 endosome lumen(GO:0031904)
0.5 9.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 12.0 GO:0005903 brush border(GO:0005903)
0.1 3.6 GO:0001533 cornified envelope(GO:0001533)
0.1 4.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 7.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 6.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 30.2 GO:0016324 apical plasma membrane(GO:0016324)
0.1 4.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 5.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 3.1 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 14.6 GO:0043025 neuronal cell body(GO:0043025)
0.0 101.8 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 35.7 GO:0015350 methotrexate transporter activity(GO:0015350)
5.4 16.3 GO:0004159 dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
3.0 30.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) efflux transmembrane transporter activity(GO:0015562) salt transmembrane transporter activity(GO:1901702)
2.5 7.5 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
2.4 7.2 GO:0019807 aspartoacylase activity(GO:0019807)
2.3 13.6 GO:0098821 BMP receptor activity(GO:0098821)
1.1 9.1 GO:0045545 syndecan binding(GO:0045545)
1.1 8.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.7 6.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.6 24.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.5 4.3 GO:0031419 cobalamin binding(GO:0031419)
0.4 3.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 12.9 GO:0016504 peptidase activator activity(GO:0016504)
0.2 4.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 12.0 GO:0008238 exopeptidase activity(GO:0008238)
0.1 14.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 36.2 GO:0005215 transporter activity(GO:0005215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 15.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 9.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.3 13.6 PID BMP PATHWAY BMP receptor signaling
0.2 6.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 8.8 PID FGF PATHWAY FGF signaling pathway
0.1 7.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 16.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.8 15.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.2 13.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 12.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 9.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 8.8 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR