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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nr6a1

Z-value: 0.55

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Transcription factors associated with Nr6a1

Gene Symbol Gene ID Gene Info
Nr6a1
ENSRNOG00000013232 nuclear receptor subfamily 6, group A, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr6a1rn6_v1_chr3_-_23066658_230666580.282.6e-07Click!

Activity profile of Nr6a1 motif

Sorted Z-values of Nr6a1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_40086870 24.61 ENSRNOT00000010027
Smpx
small muscle protein, X-linked
chr10_+_71202456 15.00 ENSRNOT00000076893
Hnf1b
HNF1 homeobox B
chr1_+_72882806 14.56 ENSRNOT00000024640
Tnni3
troponin I3, cardiac type
chr1_+_199682688 12.45 ENSRNOT00000027265
ENSRNOT00000080872
Slc5a2
solute carrier family 5 member 2
chr2_-_195423787 12.26 ENSRNOT00000071603
LOC103689947
selenium-binding protein 1
chr20_+_21316826 11.85 ENSRNOT00000000785
RGD1306739
similar to RIKEN cDNA 1700040L02
chr2_-_196113149 11.65 ENSRNOT00000088465
Selenbp1
selenium binding protein 1
chr13_+_34610684 11.30 ENSRNOT00000093019
ENSRNOT00000003280
Tfcp2l1
transcription factor CP2-like 1
chr4_+_157836912 11.28 ENSRNOT00000067271
Scnn1a
sodium channel epithelial 1 alpha subunit
chr1_-_127337882 11.04 ENSRNOT00000085158
Aldh1a3
aldehyde dehydrogenase 1 family, member A3
chr19_-_10653800 10.96 ENSRNOT00000022128
Cx3cl1
C-X3-C motif chemokine ligand 1
chr5_-_61077627 10.54 ENSRNOT00000015338
Shb
SH2 domain containing adaptor protein B
chrX_+_15225645 10.38 ENSRNOT00000008648
Glod5
glyoxalase domain containing 5
chr12_+_22153983 10.12 ENSRNOT00000080775
ENSRNOT00000001894
Pcolce
procollagen C-endopeptidase enhancer
chr17_-_65955606 9.40 ENSRNOT00000067949
ENSRNOT00000023601
Ryr2
ryanodine receptor 2
chr7_-_143016040 9.12 ENSRNOT00000029697
Krt80
keratin 80
chr8_-_47404010 7.02 ENSRNOT00000038647
Tmem136
transmembrane protein 136
chr5_-_147412705 6.73 ENSRNOT00000010688
RGD1561149
similar to mKIAA1522 protein
chr10_-_4249739 6.68 ENSRNOT00000003150
Snx29
sorting nexin 29
chr3_+_139894331 6.41 ENSRNOT00000064695
Rin2
Ras and Rab interactor 2
chr8_+_131845696 6.20 ENSRNOT00000005440
Tcaim
T cell activation inhibitor, mitochondrial
chr6_+_107531528 5.90 ENSRNOT00000077555
Acot3
acyl-CoA thioesterase 3
chr6_-_107325345 5.47 ENSRNOT00000049481
ENSRNOT00000042594
ENSRNOT00000013026
Numb
NUMB, endocytic adaptor protein
chr2_-_203494391 5.24 ENSRNOT00000021162
Ptgfrn
prostaglandin F2 receptor inhibitor
chr1_-_220787238 4.69 ENSRNOT00000083656
Tsga10ip
testis specific 10 interacting protein
chr7_-_90318221 4.47 ENSRNOT00000050774
Trps1
transcriptional repressor GATA binding 1
chr1_-_170404056 4.43 ENSRNOT00000024402
Apbb1
amyloid beta precursor protein binding family B member 1
chr8_-_63150753 4.40 ENSRNOT00000078666
Tbc1d21
TBC1 domain family, member 21
chr8_-_63155825 4.27 ENSRNOT00000011820
Tbc1d21
TBC1 domain family, member 21
chr7_+_120755516 4.20 ENSRNOT00000056169
Kdelr3
KDEL endoplasmic reticulum protein retention receptor 3
chr8_-_130475320 4.15 ENSRNOT00000075439
Ccdc13
coiled-coil domain containing 13
chr15_-_106844426 4.02 ENSRNOT00000015890
Slc15a1
solute carrier family 15 member 1
chr4_+_56591715 3.90 ENSRNOT00000041207
Fam71f1
family with sequence similarity 71, member F1
chr8_+_55037750 3.83 ENSRNOT00000013188
Timm8b
translocase of inner mitochondrial membrane 8 homolog B
chr5_-_100647727 3.78 ENSRNOT00000067435
Nfib
nuclear factor I/B
chr13_-_104080631 3.39 ENSRNOT00000032865
Lyplal1
lysophospholipase-like 1
chr1_+_167197549 3.24 ENSRNOT00000027427
Art1
ADP-ribosyltransferase 1
chr6_-_88232252 3.23 ENSRNOT00000047597
Rpl10l
ribosomal protein L10-like
chr8_-_55037604 3.21 ENSRNOT00000059169
Sdhd
succinate dehydrogenase complex subunit D
chr3_+_170475831 3.18 ENSRNOT00000006949
Fam209a
family with sequence similarity 209, member A
chr1_-_98490315 3.13 ENSRNOT00000056490
Cldnd2
claudin domain containing 2
chr11_-_84633504 2.92 ENSRNOT00000052120
Klhl24
kelch-like family member 24
chr4_-_179477070 2.90 ENSRNOT00000030680
Casc1
cancer susceptibility candidate 1
chr1_+_21141970 2.74 ENSRNOT00000017617
Akap7
A-kinase anchoring protein 7
chr12_-_30566032 2.66 ENSRNOT00000093378
Gbas
glioblastoma amplified sequence
chr7_+_2504695 2.66 ENSRNOT00000003965
Atp5b
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr4_-_65733001 2.64 ENSRNOT00000017909
Svopl
SVOP like
chr7_+_123102493 2.59 ENSRNOT00000038612
Aco2
aconitase 2
chrX_+_40460047 2.57 ENSRNOT00000010970
Phex
phosphate regulating endopeptidase homolog, X-linked
chr4_+_86125316 2.55 ENSRNOT00000045930
Ccdc129
coiled-coil domain containing 129
chr10_+_83081168 2.42 ENSRNOT00000035023
Tac4
tachykinin 4 (hemokinin)
chr7_-_12519154 2.11 ENSRNOT00000093376
ENSRNOT00000077681
Gpx4
glutathione peroxidase 4
chr20_-_48881119 2.01 ENSRNOT00000018892
Qrsl1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr1_-_71710374 1.94 ENSRNOT00000078556
ENSRNOT00000046152
Nlrp4
NLR family, pyrin domain containing 4
chr5_-_157573183 1.81 ENSRNOT00000064418
Minos1
mitochondrial inner membrane organizing system 1
chr20_+_3367208 1.70 ENSRNOT00000091149
RGD1302996
hypothetical protein MGC:15854
chr15_+_61069581 1.65 ENSRNOT00000084333
Vwa8
von Willebrand factor A domain containing 8
chr13_+_78805347 1.59 ENSRNOT00000003748
Serpinc1
serpin family C member 1
chr20_-_4489281 1.56 ENSRNOT00000031548
Cyp21a1
cytochrome P450, family 21, subfamily a, polypeptide 1
chr6_-_135026449 1.55 ENSRNOT00000009444
RGD1305298
hypothetical LOC299330
chr12_+_22727335 1.54 ENSRNOT00000077293
Znhit1
zinc finger, HIT-type containing 1
chr8_+_12160067 1.47 ENSRNOT00000036338
Maml2
mastermind-like transcriptional coactivator 2
chr1_-_260254600 1.39 ENSRNOT00000019014
Blnk
B-cell linker
chr5_-_169212170 1.34 ENSRNOT00000013385
Tas1r1
taste 1 receptor member 1
chr4_+_9821541 1.31 ENSRNOT00000015733
Slc26a5
solute carrier family 26 member 5
chr10_+_58875826 1.24 ENSRNOT00000020071
Fbxo39
F-box protein 39
chr1_-_222350173 1.19 ENSRNOT00000030625
Flrt1
fibronectin leucine rich transmembrane protein 1
chr3_-_138708332 1.17 ENSRNOT00000010678
Rbbp9
RB binding protein 9, serine hydrolase
chr3_+_143109316 1.15 ENSRNOT00000006555
LOC257643
cystatin SC
chr9_+_40975836 1.12 ENSRNOT00000084470
Ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr7_+_2831004 1.10 ENSRNOT00000029778
Rnf41
ring finger protein 41
chr5_+_156850206 1.08 ENSRNOT00000021833
Mul1
mitochondrial E3 ubiquitin protein ligase 1
chrX_+_57866709 1.05 ENSRNOT00000040923
Ppp4r3c
protein phosphatase 4 regulatory subunit 3C
chr7_-_118474609 0.94 ENSRNOT00000089076
AABR07058464.1

chr5_-_5691794 0.94 ENSRNOT00000089152
AABR07046763.1

chr1_+_193537137 0.91 ENSRNOT00000029967
AABR07005667.1

chr1_+_218532045 0.89 ENSRNOT00000018848
Mrpl21
mitochondrial ribosomal protein L21
chr9_-_30251388 0.88 ENSRNOT00000035033
Sdhaf4
succinate dehydrogenase complex assembly factor 4
chr5_-_59198650 0.83 ENSRNOT00000020958
Olr833
olfactory receptor 833
chr20_+_48881194 0.68 ENSRNOT00000000304
Rtn4ip1
reticulon 4 interacting protein 1
chr20_-_45399694 0.65 ENSRNOT00000000715
Amd1
adenosylmethionine decarboxylase 1
chrX_-_124052632 0.57 ENSRNOT00000064531
LOC691272
similar to reproductive homeobox on X chromosome, 11
chr8_-_62215293 0.53 ENSRNOT00000080448
NEWGENE_1306267
phosphopantothenoylcysteine decarboxylase
chr5_+_144281614 0.51 ENSRNOT00000014383
Trappc3
trafficking protein particle complex 3
chr1_-_84040433 0.45 ENSRNOT00000018696
Itpkc
inositol-trisphosphate 3-kinase C
chr5_+_140888973 0.44 ENSRNOT00000020524
Nt5c1a
5'-nucleotidase, cytosolic IA
chr10_-_56429748 0.37 ENSRNOT00000020675
ENSRNOT00000092704
Spem1
spermatid maturation 1
chr13_-_91228901 0.23 ENSRNOT00000071728
ENSRNOT00000073643
ENSRNOT00000071897
LOC100911825
low affinity immunoglobulin gamma Fc region receptor III-like
chr17_+_77185053 0.22 ENSRNOT00000091561
Optn
optineurin
chr1_+_80954858 0.22 ENSRNOT00000030440
Zfp112
zinc finger protein 112
chr7_-_11724843 0.19 ENSRNOT00000084144
Sppl2b
signal peptide peptidase-like 2B
chr5_+_115649046 0.10 ENSRNOT00000041328
LOC108351137
glyceraldehyde-3-phosphate dehydrogenase
chr6_+_55085313 0.06 ENSRNOT00000005458
AABR07063901.1

chr15_-_27997810 0.04 ENSRNOT00000034647
Olr1637
olfactory receptor 1637
chr1_+_99781237 0.02 ENSRNOT00000025489
Klk5
kallikrein related-peptidase 5

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr6a1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.0 GO:0061228 mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
3.7 11.0 GO:0060166 olfactory pit development(GO:0060166)
3.1 9.4 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
2.1 10.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
2.0 5.9 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
1.8 11.0 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
1.8 5.5 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
1.1 3.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.0 4.0 GO:0042938 dipeptide transport(GO:0042938)
1.0 2.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.9 3.8 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.9 11.3 GO:0007028 cytoplasm organization(GO:0007028)
0.9 2.6 GO:1904383 response to sodium phosphate(GO:1904383)
0.8 3.4 GO:0002084 protein depalmitoylation(GO:0002084)
0.7 11.8 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.7 2.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.7 2.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.7 2.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.6 4.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.5 2.4 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.4 1.3 GO:0009751 response to salicylic acid(GO:0009751)
0.4 2.6 GO:0006102 isocitrate metabolic process(GO:0006102)
0.4 1.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.4 12.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.4 1.1 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3 5.2 GO:0034389 lipid particle organization(GO:0034389)
0.2 1.3 GO:0050917 sensory perception of umami taste(GO:0050917)
0.2 11.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 11.3 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.2 1.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 4.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 1.5 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.6 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 8.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 24.6 GO:0006941 striated muscle contraction(GO:0006941)
0.1 1.1 GO:1901524 regulation of macromitophagy(GO:1901524)
0.1 3.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 3.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.6 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705)
0.1 4.4 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 4.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 8.3 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.0 2.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0046085 purine nucleoside monophosphate catabolic process(GO:0009128) adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 1.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 24.6 GO:0005927 muscle tendon junction(GO:0005927)
3.6 14.6 GO:1990584 cardiac Troponin complex(GO:1990584)
1.1 4.4 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
1.1 3.2 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
0.7 2.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.5 12.0 GO:0030057 desmosome(GO:0030057)
0.5 11.3 GO:0034706 sodium channel complex(GO:0034706)
0.4 3.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 2.7 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 9.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 22.3 GO:0001650 fibrillar center(GO:0001650)
0.1 12.5 GO:0031526 brush border membrane(GO:0031526)
0.1 1.5 GO:0000812 Swr1 complex(GO:0000812)
0.1 4.1 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 9.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.4 GO:0042629 mast cell granule(GO:0042629)
0.1 3.2 GO:0005844 polysome(GO:0005844)
0.1 7.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 4.0 GO:0005903 brush border(GO:0005903)
0.0 2.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 13.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 1.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 5.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 13.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 10.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 2.6 GO:0043209 myelin sheath(GO:0043209)
0.0 4.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.0 GO:0097209 epidermal lamellar body(GO:0097209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.6 GO:0030172 troponin C binding(GO:0030172)
3.3 26.0 GO:0008430 selenium binding(GO:0008430)
2.4 9.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
1.3 4.0 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
1.3 2.6 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
1.3 11.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
1.2 12.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
1.2 11.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
1.1 3.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.8 4.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.7 2.0 GO:0050567 amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.5 2.7 GO:0043532 angiostatin binding(GO:0043532)
0.4 11.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.4 5.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 3.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.4 1.1 GO:0005135 erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135)
0.3 10.1 GO:0016504 peptidase activator activity(GO:0016504)
0.3 11.0 GO:0048020 chemokine activity(GO:0008009) CCR chemokine receptor binding(GO:0048020)
0.3 5.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 1.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 4.4 GO:0048156 tau protein binding(GO:0048156)
0.2 2.7 GO:0016208 AMP binding(GO:0016208)
0.1 15.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 3.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.6 GO:0019808 polyamine binding(GO:0019808)
0.1 1.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 1.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 1.3 GO:0008527 taste receptor activity(GO:0008527)
0.0 8.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 4.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 1.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.6 GO:0002020 protease binding(GO:0002020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 15.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 11.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 3.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 9.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 10.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 15.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.4 14.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 3.2 REACTOME DEFENSINS Genes involved in Defensins
0.3 5.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 11.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 5.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 10.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 2.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 3.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 9.7 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.1 4.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 4.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 3.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines