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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Obox1

Z-value: 0.99

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Transcription factors associated with Obox1

Gene Symbol Gene ID Gene Info

Activity profile of Obox1 motif

Sorted Z-values of Obox1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_85645718 40.30 ENSRNOT00000032185
Gsta2
glutathione S-transferase alpha 2
chr1_-_189199376 39.70 ENSRNOT00000021027
Umod
uromodulin
chr2_+_54466280 34.13 ENSRNOT00000033112
C6
complement C6
chr2_+_199796881 32.17 ENSRNOT00000024423
Fmo5
flavin containing monooxygenase 5
chr3_+_159936856 29.57 ENSRNOT00000078703
Hnf4a
hepatocyte nuclear factor 4, alpha
chr10_-_62273119 27.30 ENSRNOT00000004322
Serpinf2
serpin family F member 2
chr14_+_22375955 27.28 ENSRNOT00000063915
ENSRNOT00000034784
Ugt2b37
UDP-glucuronosyltransferase 2 family, member 37
chr4_-_30276372 24.35 ENSRNOT00000011823
Pon1
paraoxonase 1
chr11_+_82945104 24.01 ENSRNOT00000002410
Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
chr7_+_141370491 23.60 ENSRNOT00000087662
Gpd1
glycerol-3-phosphate dehydrogenase 1
chr15_-_28104206 23.12 ENSRNOT00000032536
Ang2
angiogenin, ribonuclease A family, member 2
chr3_-_48372583 22.69 ENSRNOT00000040482
ENSRNOT00000077788
ENSRNOT00000085426
Dpp4
dipeptidylpeptidase 4
chr3_-_5802129 21.27 ENSRNOT00000009555
Sardh
sarcosine dehydrogenase
chr1_+_84304228 21.10 ENSRNOT00000024771
Prx
periaxin
chr17_-_43504604 20.73 ENSRNOT00000083829
ENSRNOT00000066313
Slc17a1
solute carrier family 17 member 1
chr16_+_54291251 20.62 ENSRNOT00000079006
Mtus1
microtubule associated tumor suppressor 1
chr1_+_189241593 19.69 ENSRNOT00000046025
Acsm5
acyl-CoA synthetase medium-chain family member 5
chr4_+_163112301 19.61 ENSRNOT00000087113
Clec12a
C-type lectin domain family 12, member A
chr7_+_94795214 19.28 ENSRNOT00000005722
Deptor
DEP domain containing MTOR-interacting protein
chr17_+_69634890 19.21 ENSRNOT00000029049
Akr1c13
aldo-keto reductase family 1, member C13
chr4_-_23135354 19.12 ENSRNOT00000011432
Steap4
STEAP4 metalloreductase
chr7_+_29435444 18.91 ENSRNOT00000008613
Slc5a8
solute carrier family 5 member 8
chr4_+_14001761 18.80 ENSRNOT00000076519
Cd36
CD36 molecule
chr5_+_136117858 18.26 ENSRNOT00000087764
Tmem53
transmembrane protein 53
chr1_+_83933942 17.58 ENSRNOT00000068690
Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
chr5_+_6373583 17.27 ENSRNOT00000084749
AABR07046778.1

chr7_+_1206648 16.19 ENSRNOT00000073689
Pros1
protein S (alpha)
chr13_-_102790639 16.13 ENSRNOT00000003177
RGD1310587
similar to hypothetical protein FLJ14146
chr16_+_72401887 16.09 ENSRNOT00000074449
LOC100910163
uncharacterized LOC100910163
chr5_-_124403195 16.02 ENSRNOT00000067850
C8a
complement C8 alpha chain
chr2_+_26240385 15.76 ENSRNOT00000024292
F2rl2
coagulation factor II (thrombin) receptor-like 2
chr14_+_6058544 15.71 ENSRNOT00000061267
Abcg3l3
ATP-binding cassette, subfamily G (WHITE), member 3-like 3
chr4_-_51199570 15.53 ENSRNOT00000010788
Slc13a1
solute carrier family 13 member 1
chr12_-_2568382 15.22 ENSRNOT00000035142
Lrrc8e
leucine rich repeat containing 8 family, member E
chr20_+_13817795 15.13 ENSRNOT00000036518
Gstt3
glutathione S-transferase, theta 3
chr3_-_93412058 14.64 ENSRNOT00000011230
Cat
catalase
chr16_+_72388880 14.59 ENSRNOT00000072459
LOC684871
similar to Protein C8orf4 (Thyroid cancer protein 1) (TC-1)
chr9_+_95221474 14.55 ENSRNOT00000066839
Ugt1a5
UDP glucuronosyltransferase family 1 member A5
chr10_+_96639924 14.41 ENSRNOT00000004756
Apoh
apolipoprotein H
chr16_+_54332660 14.23 ENSRNOT00000037685
Mtus1
microtubule associated tumor suppressor 1
chr2_-_191294374 14.06 ENSRNOT00000067469
RGD1562234
similar to S100 calcium-binding protein, ventral prostate
chr1_+_213676954 13.95 ENSRNOT00000050551
Nlrp6
NLR family, pyrin domain containing 6
chr8_-_122904913 13.90 ENSRNOT00000015188
Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
chrM_+_9870 13.85 ENSRNOT00000044582
Mt-nd4l
mitochondrially encoded NADH 4L dehydrogenase
chr16_+_50049828 13.66 ENSRNOT00000034448
Fam149a
family with sequence similarity 149, member A
chr4_-_176294997 13.58 ENSRNOT00000015112
ENSRNOT00000051461
ENSRNOT00000000026
ENSRNOT00000039877
ENSRNOT00000049303
Slc21a4
kidney specific organic anion transporter
chr5_-_78376032 13.43 ENSRNOT00000075916
Alad
aminolevulinate dehydratase
chr13_-_104080631 13.25 ENSRNOT00000032865
Lyplal1
lysophospholipase-like 1
chr18_-_48384645 13.21 ENSRNOT00000023485
Ppic
peptidylprolyl isomerase C
chr7_-_29171783 13.12 ENSRNOT00000079235
Mybpc1
myosin binding protein C, slow type
chr9_-_81400987 13.10 ENSRNOT00000035277
Tns1
tensin 1
chrM_+_7758 12.83 ENSRNOT00000046201
Mt-atp8
mitochondrially encoded ATP synthase 8
chr10_+_56662561 12.80 ENSRNOT00000025254
Asgr1
asialoglycoprotein receptor 1
chr19_+_60017746 12.72 ENSRNOT00000042623
Pard3
par-3 family cell polarity regulator
chr1_+_213686046 12.52 ENSRNOT00000019808
LOC108348167
NACHT, LRR and PYD domains-containing protein 6-like
chrM_+_11736 12.49 ENSRNOT00000048767
Mt-nd5
mitochondrially encoded NADH dehydrogenase 5
chr2_+_248649441 12.43 ENSRNOT00000067165
Kyat3
kynurenine aminotransferase 3
chr10_+_14105750 11.99 ENSRNOT00000090552
Msrb1
methionine sulfoxide reductase B1
chr5_-_159946446 11.97 ENSRNOT00000089184
Clcnka
chloride voltage-gated channel Ka
chr6_-_42630983 11.91 ENSRNOT00000071977
Atp6v1c2
ATPase H+ transporting V1 subunit C2
chr15_+_18322327 11.89 ENSRNOT00000009650
Fam3d
family with sequence similarity 3, member D
chr1_+_277068761 11.86 ENSRNOT00000044183
ENSRNOT00000022382
Habp2
hyaluronan binding protein 2
chr14_+_77067503 11.64 ENSRNOT00000085275
Slc2a9
solute carrier family 2 member 9
chrM_+_10160 11.57 ENSRNOT00000042928
Mt-nd4
mitochondrially encoded NADH dehydrogenase 4
chr2_-_193165736 11.45 ENSRNOT00000065884
Lce1l
late cornified envelope 1L
chrM_+_7919 11.32 ENSRNOT00000046108
Mt-atp6
mitochondrially encoded ATP synthase 6
chr1_-_237910012 11.00 ENSRNOT00000023664
Anxa1
annexin A1
chr1_-_226152524 10.98 ENSRNOT00000027756
Fads2
fatty acid desaturase 2
chr16_-_18766174 10.97 ENSRNOT00000084813
Sftpd
surfactant protein D
chr4_-_13878126 10.87 ENSRNOT00000007032
Gnat3
G protein subunit alpha transducin 3
chr9_-_91683468 10.75 ENSRNOT00000041550
Pid1
phosphotyrosine interaction domain containing 1
chr18_-_58423196 10.75 ENSRNOT00000025556
Piezo2
piezo-type mechanosensitive ion channel component 2
chrX_+_68771100 10.74 ENSRNOT00000043872
Stard8
StAR-related lipid transfer domain containing 8
chr6_+_47940183 10.56 ENSRNOT00000011951
Adi1
acireductone dioxygenase 1
chrM_+_5323 10.52 ENSRNOT00000050156
Mt-co1
mitochondrially encoded cytochrome c oxidase 1
chr11_+_86715981 10.09 ENSRNOT00000050269
Comt
catechol-O-methyltransferase
chr17_+_2165906 10.02 ENSRNOT00000047043
RGD1563581
similar to S100 calcium binding protein A11 (calizzarin)
chr2_+_187162017 9.82 ENSRNOT00000080693
Insrr
insulin receptor-related receptor
chr3_-_142752325 9.77 ENSRNOT00000006200
Thbd
thrombomodulin
chr4_-_58875753 9.73 ENSRNOT00000016991
Podxl
podocalyxin-like
chr5_-_148392689 9.45 ENSRNOT00000018464
ENSRNOT00000080166
Tinagl1
tubulointerstitial nephritis antigen-like 1
chr1_-_87147308 9.35 ENSRNOT00000027773
ENSRNOT00000089305
ENSRNOT00000090402
Actn4
actinin alpha 4
chr7_-_118792625 9.26 ENSRNOT00000007398
Myh9
myosin, heavy chain 9
chr5_-_107858104 9.26 ENSRNOT00000092196
Cdkn2b
cyclin-dependent kinase inhibitor 2B
chr4_+_153874852 9.13 ENSRNOT00000079744
Slc6a13
solute carrier family 6 member 13
chr9_+_17784468 9.05 ENSRNOT00000026831
Slc29a1
solute carrier family 29 member 1
chr11_+_74057361 8.99 ENSRNOT00000048746
Cpn2
carboxypeptidase N subunit 2
chr1_+_189870622 8.99 ENSRNOT00000075003
Tmem159
transmembrane protein 159
chr1_-_32141036 8.87 ENSRNOT00000078039
Slc12a7
solute carrier family 12 member 7
chr10_-_82852660 8.80 ENSRNOT00000005641
Pdk2
pyruvate dehydrogenase kinase 2
chrX_+_15225645 8.77 ENSRNOT00000008648
Glod5
glyoxalase domain containing 5
chr16_+_72268943 8.74 ENSRNOT00000032116
Ido2
indoleamine 2,3-dioxygenase 2
chr13_-_84795070 8.65 ENSRNOT00000076083
ENSRNOT00000029706
Fmo9
flavin containing monooxygenase 9
chr4_+_56337695 8.59 ENSRNOT00000071926
Lep
leptin
chrX_+_83678339 8.58 ENSRNOT00000005997
Apool
apolipoprotein O-like
chr4_+_163174487 8.51 ENSRNOT00000088108
Clec9a
C-type lectin domain family 9, member A
chr7_+_141258584 8.49 ENSRNOT00000083570
Aqp6
aquaporin 6
chr5_-_79008363 8.34 ENSRNOT00000010040
Kif12
kinesin family member 12
chr11_+_82680253 8.18 ENSRNOT00000077119
ENSRNOT00000075512
Liph
lipase H
chr3_+_43255567 8.01 ENSRNOT00000044419
Gpd2
glycerol-3-phosphate dehydrogenase 2
chr19_-_10596851 7.93 ENSRNOT00000021716
Coq9
coenzyme Q9
chr9_+_46997798 7.84 ENSRNOT00000087112
ENSRNOT00000082408
Il1r1
interleukin 1 receptor type 1
chr5_-_135025084 7.62 ENSRNOT00000018766
Tspan1
tetraspanin 1
chr10_-_63176463 7.58 ENSRNOT00000004717
Slc6a4
solute carrier family 6 member 4
chr1_+_11963836 7.32 ENSRNOT00000074325
AABR07000398.1

chr6_-_2311781 7.31 ENSRNOT00000084171
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr5_-_173611202 7.27 ENSRNOT00000047854
Agrn
agrin
chr1_-_275882444 7.26 ENSRNOT00000083215
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
chr3_-_52849907 7.12 ENSRNOT00000041096
Scn7a
sodium voltage-gated channel alpha subunit 7
chr2_-_154542557 7.11 ENSRNOT00000013392
Slc33a1
solute carrier family 33 member 1
chr17_+_32973695 7.05 ENSRNOT00000065674
RGD1565323
similar to OTTMUSP00000000621
chr5_+_14890408 7.04 ENSRNOT00000033116
Sox17
SRY box 17
chr5_+_159484370 6.94 ENSRNOT00000010593
Sdhb
succinate dehydrogenase complex iron sulfur subunit B
chr10_+_31880918 6.84 ENSRNOT00000059448
Timd4
T-cell immunoglobulin and mucin domain containing 4
chr8_-_116465801 6.83 ENSRNOT00000085915
Sema3f
semaphorin 3F
chr1_+_100161872 6.81 ENSRNOT00000025777
Klk1c3
kallikrein 1-related peptidase C3
chr14_+_23089699 6.77 ENSRNOT00000036948
Tmprss11e
transmembrane protease, serine 11e
chr18_-_74542077 6.74 ENSRNOT00000078519
Slc14a2
solute carrier family 14 member 2
chr19_+_9587653 6.71 ENSRNOT00000015956
Got2
glutamic-oxaloacetic transaminase 2
chr9_+_98490608 6.64 ENSRNOT00000027232
Klhl30
kelch-like family member 30
chr14_-_108412823 6.62 ENSRNOT00000081405
Pex13
peroxisomal biogenesis factor 13
chr3_+_92403582 6.58 ENSRNOT00000064282
Pamr1
peptidase domain containing associated with muscle regeneration 1
chr4_+_65112944 6.49 ENSRNOT00000083672
Akr1d1
aldo-keto reductase family 1, member D1
chr16_-_7250924 6.47 ENSRNOT00000025394
Stab1
stabilin 1
chr13_-_53870428 6.46 ENSRNOT00000000812
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr7_+_114323542 6.46 ENSRNOT00000012121
Chrac1
chromatin accessibility complex 1
chr1_-_241155537 6.43 ENSRNOT00000034216
ENSRNOT00000073493
Mamdc2
MAM domain containing 2
chr1_-_234596971 6.39 ENSRNOT00000017892
Trpm6
transient receptor potential cation channel, subfamily M, member 6
chr1_-_175796040 6.36 ENSRNOT00000024060
Mrvi1
murine retrovirus integration site 1 homolog
chr7_+_117326279 6.30 ENSRNOT00000050522
Spatc1
spermatogenesis and centriole associated 1
chr1_+_224824799 6.20 ENSRNOT00000024757
Slc22a6
solute carrier family 22 member 6
chr2_+_93712992 6.19 ENSRNOT00000059326
Fabp12
fatty acid binding protein 12
chr10_-_98294522 6.17 ENSRNOT00000005489
Abca8
ATP binding cassette subfamily A member 8
chr13_-_89242443 6.17 ENSRNOT00000029202
Atf6
activating transcription factor 6
chr11_-_67037115 6.15 ENSRNOT00000003137
Ildr1
immunoglobulin-like domain containing receptor 1
chr1_+_168546059 6.11 ENSRNOT00000086124
Olr101
olfactory receptor 101
chr5_-_33182715 5.97 ENSRNOT00000044483
Maged2
MAGE family member D2
chr10_-_31790263 5.96 ENSRNOT00000059468
Timd2
T-cell immunoglobulin and mucin domain containing 2
chr5_-_78378633 5.96 ENSRNOT00000076837
Alad
aminolevulinate dehydratase
chrX_+_128416722 5.92 ENSRNOT00000009336
ENSRNOT00000085110
Xiap
X-linked inhibitor of apoptosis
chr15_-_8914501 5.91 ENSRNOT00000008752
Thrb
thyroid hormone receptor beta
chr1_+_168519499 5.90 ENSRNOT00000045286
Olr98
olfactory receptor 98
chr2_-_227207584 5.85 ENSRNOT00000065361
ENSRNOT00000080215
Myoz2
myozenin 2
chr2_-_205451391 5.85 ENSRNOT00000036229
Nr1h5
nuclear receptor subfamily 1, group H, member 5
chr7_+_11081536 5.84 ENSRNOT00000007110
Ncln
nicalin
chr4_-_98305173 5.82 ENSRNOT00000010151
Il23r
interleukin 23 receptor
chr10_-_40525008 5.79 ENSRNOT00000016440
Slc36a2
solute carrier family 36 member 2
chr10_+_75365822 5.75 ENSRNOT00000055705
Vezf1
vascular endothelial zinc finger 1
chr6_-_107325345 5.72 ENSRNOT00000049481
ENSRNOT00000042594
ENSRNOT00000013026
Numb
NUMB, endocytic adaptor protein
chr15_-_23580342 5.66 ENSRNOT00000013331
ENSRNOT00000085767
Cnih1
cornichon family AMPA receptor auxiliary protein 1
chr11_-_70499200 5.64 ENSRNOT00000002439
Slc12a8
solute carrier family 12, member 8
chrM_+_3904 5.62 ENSRNOT00000040993
Mt-nd2
mitochondrially encoded NADH dehydrogenase 2
chr2_+_211546560 5.55 ENSRNOT00000033443
Aknad1
AKNA domain containing 1
chr5_+_135997052 5.44 ENSRNOT00000024921
Tctex1d4
Tctex1 domain containing 4
chr9_+_66952720 5.43 ENSRNOT00000023678
Nbeal1
neurobeachin-like 1
chr7_+_70946228 5.43 ENSRNOT00000039306
Stat6
signal transducer and activator of transcription 6
chr19_+_37675113 5.43 ENSRNOT00000024125
RGD1561415
RGD1561415
chr1_-_82279145 5.41 ENSRNOT00000057433
Cxcl17
C-X-C motif chemokine ligand 17
chr7_+_54859104 5.22 ENSRNOT00000087341
Caps2
calcyphosine 2
chr13_-_76660043 5.21 ENSRNOT00000089332
Pappa2
pappalysin 2
chr4_+_175814118 5.20 ENSRNOT00000013409
ENSRNOT00000013514
Slco1b2
solute carrier organic anion transporter family, member 1B2
chr4_+_147333056 5.18 ENSRNOT00000012137
Pparg
peroxisome proliferator-activated receptor gamma
chr17_+_77176716 5.16 ENSRNOT00000083342
ENSRNOT00000024162
Optn
optineurin
chr5_+_124476168 5.12 ENSRNOT00000077754
RGD1564074
similar to novel protein
chr5_-_22799349 5.05 ENSRNOT00000076204
Asph
aspartate-beta-hydroxylase
chr2_+_127489771 5.05 ENSRNOT00000093581
Intu
inturned planar cell polarity protein
chrX_-_23530003 5.05 ENSRNOT00000050819
Shroom2
shroom family member 2
chr7_-_5451262 5.00 ENSRNOT00000040030
LOC108349829
olfactory receptor 6C3-like
chr20_+_5646097 4.99 ENSRNOT00000090925
Itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr17_-_9441526 4.95 ENSRNOT00000000146
Txndc15
thioredoxin domain containing 15
chr3_-_75576520 4.95 ENSRNOT00000083330
Olr567
olfactory receptor 567
chr10_+_84979717 4.94 ENSRNOT00000065555
Mrpl10
mitochondrial ribosomal protein L10
chr20_-_3818045 4.92 ENSRNOT00000091622
Hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
chr14_+_84447885 4.91 ENSRNOT00000009150
Gatsl3
GATS protein-like 3
chr15_+_35548971 4.81 ENSRNOT00000075732
Olr1294
olfactory receptor 1294
chr20_+_7718282 4.80 ENSRNOT00000000593
Scube3
signal peptide, CUB domain and EGF like domain containing 3
chr11_-_71750014 4.79 ENSRNOT00000072227
LOC100911042
uncharacterized LOC100911042
chr3_-_123206828 4.79 ENSRNOT00000030192
Ddrgk1
DDRGK domain containing 1
chr14_-_71973419 4.75 ENSRNOT00000079895
Cc2d2a
coiled-coil and C2 domain containing 2A
chr7_-_139929895 4.74 ENSRNOT00000047272
Olr1104
olfactory receptor 1104
chr8_-_33345379 4.74 ENSRNOT00000030115
AABR07073381.1

chr7_+_13151592 4.70 ENSRNOT00000010203
Vom2r53
vomeronasal 2 receptor, 53
chr1_+_99648658 4.69 ENSRNOT00000039531
Klk13
kallikrein related-peptidase 13
chr12_+_30202055 4.69 ENSRNOT00000001215
Gusb
glucuronidase, beta
chr17_+_57074525 4.66 ENSRNOT00000020012
ENSRNOT00000074146
Crem
cAMP responsive element modulator
chr2_+_200572502 4.65 ENSRNOT00000074666
Zfp697
zinc finger protein 697
chr6_+_1147012 4.59 ENSRNOT00000006360
Vit
vitrin
chr5_-_115387377 4.59 ENSRNOT00000036030
ENSRNOT00000077492
RGD1560146
similar to hypothetical protein MGC34837
chr9_+_97355924 4.55 ENSRNOT00000026558
Ackr3
atypical chemokine receptor 3
chr5_-_173312023 4.54 ENSRNOT00000026671
Tas1r3
taste 1 receptor member 3
chr7_+_54859326 4.53 ENSRNOT00000039141
Caps2
calcyphosine 2
chr10_-_15306515 4.53 ENSRNOT00000060150
Nhlrc4
NHL repeat containing 4
chrX_-_13116743 4.49 ENSRNOT00000004305
Mid1ip1
MID1 interacting protein 1
chr10_-_56531483 4.47 ENSRNOT00000022343
Eif5a
eukaryotic translation initiation factor 5A
chr3_-_75923797 4.46 ENSRNOT00000073336
Olr587
olfactory receptor 587
chrX_-_18096938 4.44 ENSRNOT00000042670
LOC100912524
spindlin-2B-like
chr2_-_140464607 4.42 ENSRNOT00000058190
Ndufc1
NADH:ubiquinone oxidoreductase subunit C1
chr9_-_81469274 4.39 ENSRNOT00000070827
Cxcr1
C-X-C motif chemokine receptor 1
chr4_+_145195070 4.29 ENSRNOT00000010723
Mtmr14
myotubularin related protein 14
chrX_+_65226748 4.26 ENSRNOT00000076181
Msn
moesin

Network of associatons between targets according to the STRING database.

First level regulatory network of Obox1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.4 34.1 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
9.9 39.7 GO:0072021 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
8.1 24.3 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
7.9 23.6 GO:0006116 NADH oxidation(GO:0006116)
7.6 22.7 GO:0061744 motor behavior(GO:0061744)
7.4 29.6 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
7.0 21.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
5.9 17.6 GO:0042197 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
5.5 27.3 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
4.3 8.6 GO:0034442 regulation of lipoprotein oxidation(GO:0034442)
4.2 33.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
4.0 12.0 GO:0030091 protein repair(GO:0030091)
3.8 19.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
3.4 20.4 GO:0050917 sensory perception of umami taste(GO:0050917)
3.4 13.6 GO:0051958 methotrexate transport(GO:0051958)
3.3 13.3 GO:0002084 protein depalmitoylation(GO:0002084)
3.3 9.8 GO:0071469 cellular response to alkaline pH(GO:0071469)
3.2 19.4 GO:0010266 response to vitamin B1(GO:0010266) response to platinum ion(GO:0070541)
3.1 40.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
3.1 9.3 GO:1900756 protein processing in phagocytic vesicle(GO:1900756) regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
3.0 9.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
3.0 12.0 GO:0072053 renal inner medulla development(GO:0072053)
3.0 11.9 GO:1904975 response to bleomycin(GO:1904975)
2.8 11.0 GO:0097350 neutrophil clearance(GO:0097350)
2.7 10.8 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
2.7 16.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
2.7 21.3 GO:0006545 glycine biosynthetic process(GO:0006545)
2.6 7.8 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
2.5 10.1 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
2.4 7.3 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
2.4 7.3 GO:2000541 positive regulation of synaptic growth at neuromuscular junction(GO:0045887) regulation of sodium:potassium-exchanging ATPase activity(GO:1903406) regulation of protein geranylgeranylation(GO:2000539) positive regulation of protein geranylgeranylation(GO:2000541)
2.4 19.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
2.3 7.0 GO:0061010 inner cell mass cellular morphogenesis(GO:0001828) endodermal cell fate determination(GO:0007493) gall bladder development(GO:0061010)
2.3 9.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
2.2 8.8 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
2.2 11.0 GO:0050828 regulation of liquid surface tension(GO:0050828)
2.1 12.7 GO:0003383 apical constriction(GO:0003383)
2.0 13.9 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
1.9 5.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
1.9 7.6 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.8 5.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
1.8 3.6 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
1.8 10.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.7 8.7 GO:0070189 tryptophan catabolic process to kynurenine(GO:0019441) kynurenine metabolic process(GO:0070189)
1.7 5.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
1.7 32.4 GO:0046415 urate metabolic process(GO:0046415)
1.6 14.6 GO:0052697 xenobiotic glucuronidation(GO:0052697)
1.6 19.3 GO:0045792 negative regulation of cell size(GO:0045792)
1.6 8.0 GO:0019563 glycerol catabolic process(GO:0019563)
1.6 4.8 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
1.6 15.6 GO:0009650 UV protection(GO:0009650)
1.5 4.4 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
1.4 5.8 GO:0010958 regulation of amino acid import(GO:0010958)
1.4 7.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.4 4.2 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
1.4 9.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.3 15.8 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
1.3 13.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.3 40.5 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
1.3 6.5 GO:0061113 pancreas morphogenesis(GO:0061113)
1.3 21.8 GO:1902358 sulfate transmembrane transport(GO:1902358)
1.2 6.2 GO:0031427 urate transport(GO:0015747) response to methotrexate(GO:0031427)
1.1 6.8 GO:0097491 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
1.1 3.4 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
1.1 9.0 GO:0051182 coenzyme transport(GO:0051182)
1.1 6.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
1.1 25.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.1 3.2 GO:0035964 COPI-coated vesicle budding(GO:0035964)
1.0 5.9 GO:0097039 protein linear polyubiquitination(GO:0097039)
1.0 5.9 GO:0008050 female courtship behavior(GO:0008050)
1.0 20.9 GO:0006855 drug transmembrane transport(GO:0006855)
0.9 2.8 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.9 10.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.9 25.3 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.9 3.5 GO:0006004 fucose metabolic process(GO:0006004)
0.9 24.2 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.9 4.3 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.8 2.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.8 2.5 GO:1901740 skeletal myofibril assembly(GO:0014866) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.8 6.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.8 3.9 GO:0035973 aggrephagy(GO:0035973)
0.8 16.2 GO:0042730 fibrinolysis(GO:0042730)
0.8 2.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.7 6.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.7 4.5 GO:0045901 regulation of translational termination(GO:0006449) positive regulation of translational elongation(GO:0045901)
0.7 13.9 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.7 8.6 GO:0042407 cristae formation(GO:0042407)
0.7 9.3 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.7 2.8 GO:0045903 positive regulation of translational fidelity(GO:0045903) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.7 4.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.7 2.0 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.6 11.0 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.6 6.4 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.6 3.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.6 4.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.6 2.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.5 11.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.5 2.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.5 1.6 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.5 4.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.5 16.2 GO:0019835 cytolysis(GO:0019835)
0.5 5.2 GO:1904417 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734) regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.5 1.4 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.5 1.4 GO:0089709 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.5 6.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.5 6.9 GO:0006105 succinate metabolic process(GO:0006105)
0.5 2.7 GO:0030222 eosinophil differentiation(GO:0030222)
0.4 5.8 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.4 1.3 GO:0045401 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.4 2.2 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.4 6.0 GO:0097286 iron ion import(GO:0097286)
0.4 6.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.4 3.7 GO:0090527 actin filament reorganization(GO:0090527)
0.4 2.7 GO:0019348 dolichol metabolic process(GO:0019348)
0.4 9.8 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.4 5.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.3 3.8 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.3 24.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.3 19.7 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.3 3.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 3.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 2.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 3.7 GO:0009642 response to light intensity(GO:0009642)
0.3 10.5 GO:0018149 peptide cross-linking(GO:0018149)
0.3 1.9 GO:0098535 de novo centriole assembly(GO:0098535)
0.3 1.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.3 7.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.3 2.9 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.3 2.7 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.3 3.4 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.2 1.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.2 2.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 3.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 1.4 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.2 2.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 2.3 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.2 5.0 GO:0032438 melanosome organization(GO:0032438)
0.2 4.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.2 8.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 10.7 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.2 2.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 1.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.2 4.0 GO:0033194 response to hydroperoxide(GO:0033194)
0.2 0.9 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
0.2 1.6 GO:0007000 nucleolus organization(GO:0007000)
0.2 1.7 GO:0060019 radial glial cell differentiation(GO:0060019)
0.2 2.4 GO:0036315 cellular response to sterol(GO:0036315)
0.2 0.5 GO:0048749 compound eye development(GO:0048749)
0.2 2.3 GO:0051764 actin crosslink formation(GO:0051764)
0.2 7.6 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.2 1.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 0.7 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.2 1.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 1.0 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 4.6 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 21.4 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.1 1.8 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 4.8 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.6 GO:0015755 fructose transport(GO:0015755) cellular response to fructose stimulus(GO:0071332)
0.1 2.1 GO:0015671 oxygen transport(GO:0015671)
0.1 2.0 GO:0035988 chondrocyte proliferation(GO:0035988) collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 2.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 7.1 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 3.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 31.1 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.1 4.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 1.4 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 2.2 GO:0042832 defense response to protozoan(GO:0042832)
0.1 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 2.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 3.9 GO:0046039 GTP metabolic process(GO:0046039)
0.1 1.1 GO:0010543 regulation of platelet activation(GO:0010543)
0.1 5.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 2.7 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 5.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 3.4 GO:0018345 protein palmitoylation(GO:0018345)
0.1 135.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 5.7 GO:0001885 endothelial cell development(GO:0001885)
0.1 5.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 2.3 GO:0006301 postreplication repair(GO:0006301)
0.1 1.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.1 GO:0035855 megakaryocyte development(GO:0035855)
0.1 4.1 GO:0030239 myofibril assembly(GO:0030239)
0.1 0.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 9.4 GO:0044070 regulation of anion transport(GO:0044070)
0.1 2.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 3.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 7.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 1.4 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 4.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 4.1 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.9 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 3.6 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 3.3 GO:0032543 mitochondrial translation(GO:0032543)
0.1 1.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.4 GO:0090166 positive regulation of protein glycosylation(GO:0060050) Golgi disassembly(GO:0090166) spindle assembly involved in meiosis(GO:0090306)
0.1 48.6 GO:0055114 oxidation-reduction process(GO:0055114)
0.1 1.2 GO:0048240 sperm capacitation(GO:0048240)
0.1 3.5 GO:0031016 pancreas development(GO:0031016)
0.1 4.8 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.1 0.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 3.1 GO:0030500 regulation of bone mineralization(GO:0030500)
0.1 0.7 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.1 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 4.3 GO:0007605 sensory perception of sound(GO:0007605)
0.0 3.1 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.6 GO:0046130 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 2.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.6 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 2.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 5.2 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.9 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.1 GO:0007595 lactation(GO:0007595)
0.0 0.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.9 GO:0031648 protein destabilization(GO:0031648)
0.0 2.3 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.9 GO:0007566 embryo implantation(GO:0007566)
0.0 1.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 2.7 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.6 GO:0016525 negative regulation of angiogenesis(GO:0016525)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 50.2 GO:0005579 membrane attack complex(GO:0005579)
6.3 31.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
3.4 27.3 GO:0005577 fibrinogen complex(GO:0005577)
3.2 22.7 GO:0071438 invadopodium membrane(GO:0071438)
2.9 8.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
2.7 24.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
2.4 11.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
2.3 9.3 GO:0097513 myosin II filament(GO:0097513)
2.3 6.9 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
2.1 12.7 GO:0033269 internode region of axon(GO:0033269)
1.7 45.3 GO:0005640 nuclear outer membrane(GO:0005640)
1.6 24.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
1.6 14.4 GO:0042627 chylomicron(GO:0042627)
1.5 6.2 GO:0061689 tricellular tight junction(GO:0061689)
1.2 8.6 GO:0061617 MICOS complex(GO:0061617)
1.2 11.0 GO:0031313 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
1.2 13.1 GO:0032982 myosin filament(GO:0032982)
1.1 55.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.1 13.9 GO:0061702 inflammasome complex(GO:0061702)
1.0 13.6 GO:0031143 pseudopodium(GO:0031143)
1.0 3.9 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
1.0 9.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.9 4.5 GO:1903767 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
0.9 5.5 GO:0005642 annulate lamellae(GO:0005642)
0.7 2.2 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.7 10.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.7 39.3 GO:0060170 ciliary membrane(GO:0060170)
0.7 7.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.6 5.3 GO:0031209 SCAR complex(GO:0031209)
0.6 11.0 GO:0005614 interstitial matrix(GO:0005614)
0.5 5.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.5 2.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.5 7.3 GO:0043083 synaptic cleft(GO:0043083)
0.4 9.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.4 10.5 GO:0001533 cornified envelope(GO:0001533)
0.4 1.9 GO:0098536 deuterosome(GO:0098536)
0.4 14.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 7.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 28.8 GO:0031526 brush border membrane(GO:0031526)
0.3 6.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.3 4.8 GO:0036038 MKS complex(GO:0036038)
0.3 2.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.3 2.8 GO:0033263 CORVET complex(GO:0033263)
0.3 4.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 2.1 GO:0005833 hemoglobin complex(GO:0005833)
0.3 14.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3 2.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 24.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 25.2 GO:0072562 blood microparticle(GO:0072562)
0.2 6.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 0.6 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 1.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.2 7.9 GO:0005771 multivesicular body(GO:0005771)
0.2 58.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 7.1 GO:0031941 filamentous actin(GO:0031941)
0.2 4.5 GO:0031430 M band(GO:0031430)
0.2 49.2 GO:0016324 apical plasma membrane(GO:0016324)
0.1 10.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 5.4 GO:0001772 immunological synapse(GO:0001772)
0.1 1.1 GO:0097542 ciliary tip(GO:0097542)
0.1 2.8 GO:0035869 ciliary transition zone(GO:0035869)
0.1 1.8 GO:0005916 fascia adherens(GO:0005916)
0.1 87.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 43.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 2.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 5.8 GO:0030315 T-tubule(GO:0030315)
0.1 6.7 GO:0005901 caveola(GO:0005901)
0.1 9.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 2.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 5.9 GO:0036126 sperm flagellum(GO:0036126)
0.1 81.6 GO:0005615 extracellular space(GO:0005615)
0.1 3.0 GO:0015030 Cajal body(GO:0015030)
0.1 4.1 GO:0030018 Z disc(GO:0030018)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 3.8 GO:0005776 autophagosome(GO:0005776)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.6 GO:0032432 actin filament bundle(GO:0032432)
0.0 5.2 GO:0005774 vacuolar membrane(GO:0005774)
0.0 7.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 6.4 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 1.5 GO:0030016 myofibril(GO:0030016)
0.0 0.8 GO:0031514 motile cilium(GO:0031514)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.9 GO:0005769 early endosome(GO:0005769)
0.0 2.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.6 GO:0015629 actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 24.3 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
7.9 31.6 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368)
6.5 19.4 GO:0004655 porphobilinogen synthase activity(GO:0004655)
6.0 24.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
4.9 14.6 GO:0004046 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
4.8 14.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
4.8 19.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
3.9 15.8 GO:0015057 thrombin receptor activity(GO:0015057)
3.8 18.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
3.4 40.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
3.4 13.6 GO:0015350 methotrexate transporter activity(GO:0015350)
3.3 39.8 GO:0019864 IgG binding(GO:0019864)
3.2 19.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
3.1 9.3 GO:0031762 follicle-stimulating hormone receptor binding(GO:0031762)
3.0 12.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.9 8.7 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
2.7 11.0 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
2.6 7.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
2.5 7.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
2.5 29.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
2.5 19.7 GO:0003996 acyl-CoA ligase activity(GO:0003996)
2.3 6.9 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
2.3 22.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
2.2 40.3 GO:0043295 glutathione binding(GO:0043295)
2.2 11.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
2.2 8.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
2.2 6.5 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
2.1 20.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
2.1 6.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
1.9 5.8 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
1.9 51.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.9 13.2 GO:0016018 cyclosporin A binding(GO:0016018)
1.8 9.0 GO:0051185 coenzyme transporter activity(GO:0051185)
1.8 17.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.6 4.9 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
1.6 21.3 GO:0005542 folic acid binding(GO:0005542)
1.6 4.7 GO:0004566 beta-glucuronidase activity(GO:0004566)
1.5 9.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
1.5 4.4 GO:0004918 interleukin-8 receptor activity(GO:0004918)
1.5 5.8 GO:0005143 interleukin-12 receptor binding(GO:0005143)
1.4 9.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.4 21.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
1.3 41.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
1.3 11.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.3 13.9 GO:0005000 vasopressin receptor activity(GO:0005000)
1.2 5.0 GO:0043533 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.2 7.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.2 14.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.2 9.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.2 10.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.2 15.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.2 5.9 GO:0051373 FATZ binding(GO:0051373)
1.2 13.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.0 5.2 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
1.0 13.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
1.0 3.9 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.9 2.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.9 4.6 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.9 4.5 GO:0033041 sweet taste receptor activity(GO:0033041)
0.9 2.7 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.9 3.6 GO:0045159 myosin II binding(GO:0045159)
0.9 3.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.9 3.5 GO:0042806 fucose binding(GO:0042806)
0.9 5.2 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.8 16.0 GO:0001848 complement binding(GO:0001848)
0.8 19.7 GO:0019825 oxygen binding(GO:0019825)
0.8 6.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.8 9.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.8 2.3 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.7 5.2 GO:0050692 DBD domain binding(GO:0050692)
0.7 2.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.7 12.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.7 16.1 GO:0005112 Notch binding(GO:0005112)
0.7 9.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.7 3.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.6 2.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.6 10.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.6 8.5 GO:0015250 water channel activity(GO:0015250)
0.6 4.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.5 11.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.5 5.9 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.5 18.8 GO:0038024 cargo receptor activity(GO:0038024)
0.5 1.6 GO:0050497 methylthiotransferase activity(GO:0035596) transferase activity, transferring alkylthio groups(GO:0050497)
0.5 6.8 GO:0045499 chemorepellent activity(GO:0045499)
0.5 1.4 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.5 10.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.5 8.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.4 10.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4 5.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 4.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.4 9.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4 7.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.4 2.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 7.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.4 6.2 GO:0035497 cAMP response element binding(GO:0035497)
0.4 4.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.4 2.6 GO:0034046 poly(G) binding(GO:0034046)
0.3 12.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 3.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.3 3.8 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.3 9.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.3 2.0 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.3 2.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 3.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 1.3 GO:0019767 IgE receptor activity(GO:0019767)
0.3 1.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.3 28.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.2 3.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 2.4 GO:0033691 sialic acid binding(GO:0033691)
0.2 2.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 7.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.2 1.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 5.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 2.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 5.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 1.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 1.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 18.4 GO:0004540 ribonuclease activity(GO:0004540)
0.2 0.9 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 6.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 7.3 GO:0070330 aromatase activity(GO:0070330)
0.2 3.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 1.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 1.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 18.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 65.3 GO:0005549 odorant binding(GO:0005549)
0.2 4.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 0.9 GO:0000405 bubble DNA binding(GO:0000405)
0.2 3.6 GO:0008527 taste receptor activity(GO:0008527)
0.1 2.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 29.2 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 11.6 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 2.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 2.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 2.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 2.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 3.7 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.6 GO:0031005 filamin binding(GO:0031005)
0.1 6.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 5.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 69.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.5 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 4.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 0.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.7 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.6 GO:0070061 fructose binding(GO:0070061)
0.1 6.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 2.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.7 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 1.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 6.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 1.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 4.3 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 20.8 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 4.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 2.3 GO:0016874 ligase activity(GO:0016874)
0.0 7.2 GO:0016491 oxidoreductase activity(GO:0016491)
0.0 1.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.2 GO:0008083 growth factor activity(GO:0008083)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 14.6 PID FOXO PATHWAY FoxO family signaling
1.0 15.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.5 29.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 2.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 50.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 3.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 5.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 19.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.3 12.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 9.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 11.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 5.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.2 5.0 ST GAQ PATHWAY G alpha q Pathway
0.2 5.8 PID IL23 PATHWAY IL23-mediated signaling events
0.2 4.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 6.1 PID IL1 PATHWAY IL1-mediated signaling events
0.2 3.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 8.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 34.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.1 PID BARD1 PATHWAY BARD1 signaling events
0.1 4.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 3.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 3.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 2.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 3.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.1 PID EPO PATHWAY EPO signaling pathway
0.1 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 66.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.6 31.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
1.5 14.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.3 40.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
1.2 29.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
1.1 19.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.1 15.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.1 11.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.0 3.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
1.0 8.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.0 30.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.9 5.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.8 12.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.8 45.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.8 14.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.7 8.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 9.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 12.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.6 2.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.6 57.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.6 6.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 19.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.6 10.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.6 8.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.6 6.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.5 6.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 6.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.5 15.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.5 5.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.5 11.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.4 5.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.4 6.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 6.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 10.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.3 13.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 9.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 6.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 7.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 10.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.3 5.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 6.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.3 3.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 4.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 5.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 12.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 2.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 6.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 2.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 5.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 2.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 4.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.4 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 1.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 2.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 0.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 3.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 4.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.1 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 2.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4