ISMARA results: Plag1

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Plag1

Z-value: 1.28

Motif logo

Transcription factors associated with Plag1

Gene Symbol	Gene ID	Gene Info
Plag1 NCBI RGD Ensembl	ENSRNOG00000008846	PLAG1 zinc finger

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Plag1	rn6_v1_chr5_-_16799776_16799776	0.20	4.4e-04	Click!

Activity profile of Plag1 motif

Sorted Z-values of Plag1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_198232344 Show fit	40.83	ENSRNOT00000080988	Aldoa NCBI RGD Ensembl Show fit	aldolase, fructose-bisphosphate A
chr10_+_57278307 Show fit	38.04	ENSRNOT00000005612	Eno3 NCBI RGD Ensembl Show fit	enolase 3
chr9_+_81821346 Show fit	36.53	ENSRNOT00000022234	Plcd4 NCBI RGD Ensembl Show fit	phospholipase C, delta 4
chr1_+_198655742 Show fit	35.05	ENSRNOT00000023944	Mylpf NCBI RGD Ensembl Show fit	myosin light chain, phosphorylatable, fast skeletal muscle
chr1_-_220136470 Show fit	34.75	ENSRNOT00000026812	Actn3 NCBI RGD Ensembl Show fit	actinin alpha 3
chr1_-_215834704 Show fit	31.82	ENSRNOT00000073850	Igf2 NCBI RGD Ensembl Show fit	insulin-like growth factor 2
chr1_-_88066101 Show fit	31.17	ENSRNOT00000079473 ENSRNOT00000027893	Ryr1 NCBI RGD Ensembl Show fit	ryanodine receptor 1
chr1_+_101427195 Show fit	29.85	ENSRNOT00000028271	Gys1 NCBI RGD Ensembl Show fit	glycogen synthase 1
chrX_-_78496847 Show fit	28.28	ENSRNOT00000003265	Itm2a NCBI RGD Ensembl Show fit	integral membrane protein 2A
chr5_+_148528725 Show fit	26.86	ENSRNOT00000017325	Fabp3 NCBI RGD Ensembl Show fit	fatty acid binding protein 3
chr10_-_45480999 Show fit	26.83	ENSRNOT00000078353 ENSRNOT00000084697 ENSRNOT00000087926	Obscn NCBI RGD Ensembl Show fit	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr19_+_880024 Show fit	26.64	ENSRNOT00000061648	Cmtm2a NCBI RGD Ensembl Show fit	CKLF-like MARVEL transmembrane domain containing 2A
chr7_-_50638798 Show fit	26.62	ENSRNOT00000048880	Syt1 NCBI RGD Ensembl Show fit	synaptotagmin 1
chr18_+_36371041 Show fit	26.02	ENSRNOT00000025408	Sh3rf2 NCBI RGD Ensembl Show fit	SH3 domain containing ring finger 2
chr10_+_14094754 Show fit	25.25	ENSRNOT00000019660	Rpl3l NCBI RGD Ensembl Show fit	ribosomal protein L3-like
chr1_-_222246765 Show fit	24.49	ENSRNOT00000087285 ENSRNOT00000028731	Dnajc4 NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member C4
chr4_+_56674832 Show fit	24.14	ENSRNOT00000060309	Ccdc136 NCBI RGD Ensembl Show fit	coiled-coil domain containing 136
chr2_+_188844073 Show fit	24.11	ENSRNOT00000028117	Kcnn3 NCBI RGD Ensembl Show fit	potassium calcium-activated channel subfamily N member 3
chr6_-_99783047 Show fit	24.04	ENSRNOT00000009028	Sptb NCBI RGD Ensembl Show fit	spectrin, beta, erythrocytic
chr13_+_51034256 Show fit	23.47	ENSRNOT00000004528 ENSRNOT00000046854 ENSRNOT00000087320	Mybph NCBI RGD Ensembl Show fit	myosin binding protein H
chr1_+_81372650 Show fit	23.36	ENSRNOT00000088829	Zfp428 NCBI RGD Ensembl Show fit	zinc finger protein 428
chr17_-_71105286 Show fit	22.97	ENSRNOT00000025901	Prkcq NCBI RGD Ensembl Show fit	protein kinase C, theta
chrX_+_159112880 Show fit	22.68	ENSRNOT00000084594	Fhl1 NCBI RGD Ensembl Show fit	four and a half LIM domains 1
chr5_+_148193710 Show fit	22.33	ENSRNOT00000088568	Adgrb2 NCBI RGD Ensembl Show fit	adhesion G protein-coupled receptor B2
chrX_-_72133692 Show fit	21.47	ENSRNOT00000004263	Cited1 NCBI RGD Ensembl Show fit	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr1_+_72889270 Show fit	21.40	ENSRNOT00000058843 ENSRNOT00000034957	Tnnt1 NCBI RGD Ensembl Show fit	troponin T1, slow skeletal type
chr1_+_197839430 Show fit	21.05	ENSRNOT00000025043	Rabep2 NCBI RGD Ensembl Show fit	rabaptin, RAB GTPase binding effector protein 2
chr13_-_52197205 Show fit	20.46	ENSRNOT00000009712	Shisa4 NCBI RGD Ensembl Show fit	shisa family member 4
chr13_+_104284660 Show fit	20.17	ENSRNOT00000005400	Dusp10 NCBI RGD Ensembl Show fit	dual specificity phosphatase 10
chr18_-_28454756 Show fit	20.15	ENSRNOT00000040091	Spata24 NCBI RGD Ensembl Show fit	spermatogenesis associated 24
chr1_-_73753128 Show fit	20.13	ENSRNOT00000068459	Ttyh1 NCBI RGD Ensembl Show fit	tweety family member 1
chr8_+_48422036 Show fit	19.84	ENSRNOT00000036051	Usp2 NCBI RGD Ensembl Show fit	ubiquitin specific peptidase 2
chr1_-_205030567 Show fit	19.81	ENSRNOT00000023404	Ctbp2 NCBI RGD Ensembl Show fit	C-terminal binding protein 2
chr9_+_14529218 Show fit	19.66	ENSRNOT00000016893	Apobec2 NCBI RGD Ensembl Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr9_+_99998275 Show fit	19.21	ENSRNOT00000074395	Gpc1 NCBI RGD Ensembl Show fit	glypican 1
chr14_-_77810147 Show fit	19.14	ENSRNOT00000035427	Cytl1 NCBI RGD Ensembl Show fit	cytokine like 1
chr20_+_13778178 Show fit	18.34	ENSRNOT00000058314	Gstt4 NCBI RGD Ensembl Show fit	glutathione S-transferase, theta 4
chr19_-_43290363 Show fit	17.92	ENSRNOT00000024248	St3gal2 NCBI RGD Ensembl Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chrX_-_29648359 Show fit	17.90	ENSRNOT00000086721 ENSRNOT00000006777	Gpm6b NCBI RGD Ensembl Show fit	glycoprotein m6b
chr10_-_82209459 Show fit	17.68	ENSRNOT00000004377	Spata20 NCBI RGD Ensembl Show fit	spermatogenesis associated 20
chr3_+_148386189 Show fit	17.62	ENSRNOT00000011255	Mylk2 NCBI RGD Ensembl Show fit	myosin light chain kinase 2
chrX_+_114929029 Show fit	17.49	ENSRNOT00000006459	Pak3 NCBI RGD Ensembl Show fit	p21 (RAC1) activated kinase 3
chr2_+_198797159 Show fit	16.93	ENSRNOT00000056225	Ankrd35 NCBI RGD Ensembl Show fit	ankyrin repeat domain 35
chr1_+_84328114 Show fit	16.90	ENSRNOT00000028266	Hipk4 NCBI RGD Ensembl Show fit	homeodomain interacting protein kinase 4
chr2_-_210241455 Show fit	16.88	ENSRNOT00000086420	Kcnc4 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily C member 4
chr1_+_215666628 Show fit	16.28	ENSRNOT00000040598 ENSRNOT00000066135 ENSRNOT00000051425 ENSRNOT00000080339 ENSRNOT00000066896 ENSRNOT00000063918	Tnnt3 NCBI RGD Ensembl Show fit	troponin T3, fast skeletal type
chr1_+_101324652 Show fit	16.27	ENSRNOT00000028116	Hrc NCBI RGD Ensembl Show fit	histidine rich calcium binding protein
chr6_-_133716847 Show fit	16.00	ENSRNOT00000072399	Rtl1 NCBI RGD Ensembl Show fit	retrotransposon-like 1
chr8_+_56179816 Show fit	15.94	ENSRNOT00000059078	Arhgap20 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 20
chr16_-_20686317 Show fit	15.76	ENSRNOT00000060097	Crlf1 NCBI RGD Ensembl Show fit	cytokine receptor-like factor 1
chr6_-_135412312 Show fit	15.28	ENSRNOT00000010610	Ankrd9 NCBI RGD Ensembl Show fit	ankyrin repeat domain 9
chr5_+_167109691 Show fit	15.23	ENSRNOT00000055536	Gpr157 NCBI RGD Ensembl Show fit	G protein-coupled receptor 157
chr7_-_139483997 Show fit	15.18	ENSRNOT00000086062	Col2a1 NCBI RGD Ensembl Show fit	collagen type II alpha 1 chain
chr19_-_37427989 Show fit	15.15	ENSRNOT00000022863	Tppp3 NCBI RGD Ensembl Show fit	tubulin polymerization-promoting protein family member 3
chr9_-_55673704 Show fit	15.14	ENSRNOT00000066231 ENSRNOT00000081677	Tmeff2 NCBI RGD Ensembl Show fit	transmembrane protein with EGF-like and two follistatin-like domains 2
chr10_-_58973020 Show fit	15.04	ENSRNOT00000020379	Smtnl2 NCBI RGD Ensembl Show fit	smoothelin-like 2
chr1_+_222519615 Show fit	15.00	ENSRNOT00000083585	Rcor2 NCBI RGD Ensembl Show fit	REST corepressor 2
chr1_+_36185916 Show fit	14.89	ENSRNOT00000041762	Ube2ql1 NCBI RGD Ensembl Show fit	ubiquitin-conjugating enzyme E2Q family-like 1
chr7_+_15785410 Show fit	14.83	ENSRNOT00000082664 ENSRNOT00000073235	Zfp955a NCBI RGD Ensembl Show fit	zinc finger protein 955A
chr9_+_82556573 Show fit	14.66	ENSRNOT00000026860	Des NCBI RGD Ensembl Show fit	desmin
chr10_-_95934345 Show fit	14.62	ENSRNOT00000004349	Cacng1 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit gamma 1
chr1_-_84491466 Show fit	14.39	ENSRNOT00000034609	Map3k10 NCBI RGD Ensembl Show fit	mitogen activated protein kinase kinase kinase 10
chr7_-_70556827 Show fit	14.38	ENSRNOT00000007721	Kif5a NCBI RGD Ensembl Show fit	kinesin family member 5A
chr10_+_56546710 Show fit	14.21	ENSRNOT00000023003	Ybx2 NCBI RGD Ensembl Show fit	Y box binding protein 2
chr6_+_105364668 Show fit	14.11	ENSRNOT00000009513 ENSRNOT00000087090	Ttc9 NCBI RGD Ensembl Show fit	tetratricopeptide repeat domain 9
chr14_+_60764409 Show fit	14.09	ENSRNOT00000005168	Lgi2 NCBI RGD Ensembl Show fit	leucine-rich repeat LGI family, member 2
chr13_-_91872954 Show fit	14.05	ENSRNOT00000004613 ENSRNOT00000079263	Cadm3 NCBI RGD Ensembl Show fit	cell adhesion molecule 3
chr18_-_76878981 Show fit	14.01	ENSRNOT00000088054	Kcng2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel modifier subfamily G member 2
chr17_-_19580929 Show fit	13.90	ENSRNOT00000023613	Gmpr NCBI RGD Ensembl Show fit	guanosine monophosphate reductase
chr1_-_101351879 Show fit	13.86	ENSRNOT00000028142	Ppfia3 NCBI RGD Ensembl Show fit	PTPRF interacting protein alpha 3
chr7_-_70552897 Show fit	13.65	ENSRNOT00000080594	Kif5a NCBI RGD Ensembl Show fit	kinesin family member 5A
chr15_+_42960307 Show fit	13.53	ENSRNOT00000012528	Trim35 NCBI RGD Ensembl Show fit	tripartite motif-containing 35
chr15_-_42638392 Show fit	13.49	ENSRNOT00000022020	Scara3 NCBI RGD Ensembl Show fit	scavenger receptor class A, member 3
chr10_+_94170766 Show fit	13.48	ENSRNOT00000010627	Ace NCBI RGD Ensembl Show fit	angiotensin I converting enzyme
chr20_+_6923489 Show fit	13.39	ENSRNOT00000093373 ENSRNOT00000000632	Pi16 NCBI RGD Ensembl Show fit	peptidase inhibitor 16
chr5_-_59025631 Show fit	13.37	ENSRNOT00000049000 ENSRNOT00000022801	Tpm2 NCBI RGD Ensembl Show fit	tropomyosin 2, beta
chr15_-_104168564 Show fit	13.34	ENSRNOT00000093385 ENSRNOT00000038596	Dzip1 NCBI RGD Ensembl Show fit	DAZ interacting zinc finger protein 1
chr8_+_118013612 Show fit	13.17	ENSRNOT00000056166	Map4 NCBI RGD Ensembl Show fit	microtubule-associated protein 4
chr8_+_59344083 Show fit	13.16	ENSRNOT00000031175	Crabp1 NCBI RGD Ensembl Show fit	cellular retinoic acid binding protein 1
chr20_+_5049496 Show fit	12.97	ENSRNOT00000088251 ENSRNOT00000001118	Ddah2 NCBI RGD Ensembl Show fit	dimethylarginine dimethylaminohydrolase 2
chr7_+_11383116 Show fit	12.96	ENSRNOT00000066348	Nmrk2 NCBI RGD Ensembl Show fit	nicotinamide riboside kinase 2
chr8_-_72841496 Show fit	12.87	ENSRNOT00000057641 ENSRNOT00000040808 ENSRNOT00000085894 ENSRNOT00000024575 ENSRNOT00000048044 ENSRNOT00000024493	Tpm1 NCBI RGD Ensembl Show fit	tropomyosin 1, alpha
chr1_+_274391932 Show fit	12.75	ENSRNOT00000054685	Rbm20 NCBI RGD Ensembl Show fit	RNA binding motif protein 20
chr5_-_146446227 Show fit	12.56	ENSRNOT00000044868	Hmgb4 NCBI RGD Ensembl Show fit	high-mobility group box 4
chr7_-_117722703 Show fit	12.24	ENSRNOT00000093083 ENSRNOT00000092789	Cyhr1 NCBI RGD Ensembl Show fit	cysteine and histidine rich 1
chr17_+_70684134 Show fit	12.24	ENSRNOT00000025731 ENSRNOT00000068354	Pfkfb3 NCBI RGD Ensembl Show fit	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chrX_+_39711201 Show fit	12.17	ENSRNOT00000080512 ENSRNOT00000009802	Cnksr2 NCBI RGD Ensembl Show fit	connector enhancer of kinase suppressor of Ras 2
chr20_+_7136007 Show fit	12.10	ENSRNOT00000000580	Hmga1 NCBI RGD Ensembl Show fit	high mobility group AT-hook 1
chr3_-_113312127 Show fit	11.95	ENSRNOT00000065285	Mfap1a NCBI RGD Ensembl Show fit	microfibrillar-associated protein 1A
chr1_+_100832324 Show fit	11.82	ENSRNOT00000056364	Il4i1 NCBI RGD Ensembl Show fit	interleukin 4 induced 1
chr10_-_91302155 Show fit	11.80	ENSRNOT00000004371	Spata32 NCBI RGD Ensembl Show fit	spermatogenesis associated 32
chr1_-_128695796 Show fit	11.74	ENSRNOT00000076329	Synm NCBI RGD Ensembl Show fit	synemin
chr4_-_133951264 Show fit	11.71	ENSRNOT00000090506	Pdzrn3 NCBI RGD Ensembl Show fit	PDZ domain containing RING finger 3
chr19_-_10596851 Show fit	11.53	ENSRNOT00000021716	Coq9 NCBI RGD Ensembl Show fit	coenzyme Q9
chr14_-_84170835 Show fit	11.52	ENSRNOT00000005646	Slc35e4 NCBI RGD Ensembl Show fit	solute carrier family 35, member E4
chr15_-_52116001 Show fit	11.51	ENSRNOT00000013284	Piwil2 NCBI RGD Ensembl Show fit	piwi-like RNA-mediated gene silencing 2
chr2_-_187372652 Show fit	11.49	ENSRNOT00000025496 ENSRNOT00000083116	Bcan NCBI RGD Ensembl Show fit	brevican
chr1_+_81260548 Show fit	11.47	ENSRNOT00000026669	Smg9 NCBI RGD Ensembl Show fit	SMG9 nonsense mediated mRNA decay factor
chr7_-_74901997 Show fit	11.47	ENSRNOT00000039378	Rgs22 NCBI RGD Ensembl Show fit	regulator of G-protein signaling 22
chr5_-_25584278 Show fit	11.44	ENSRNOT00000090579 ENSRNOT00000090376	Pdp1 NCBI RGD Ensembl Show fit	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr12_-_21760292 Show fit	11.43	ENSRNOT00000059592	LOC102550456 NCBI RGD Ensembl Show fit	TSC22 domain family protein 4-like
chr12_-_40590361 Show fit	11.40	ENSRNOT00000067503	Tmem116 NCBI RGD Ensembl Show fit	transmembrane protein 116
chr1_+_264796812 Show fit	11.35	ENSRNOT00000021171	Sfxn3 NCBI RGD Ensembl Show fit	sideroflexin 3
chr10_-_39405311 Show fit	11.31	ENSRNOT00000074616	Pdlim4 NCBI RGD Ensembl Show fit	PDZ and LIM domain 4
chr1_+_101474334 Show fit	11.28	ENSRNOT00000064245	Tulp2 NCBI RGD Ensembl Show fit	tubby-like protein 2
chr9_-_44237117 Show fit	11.24	ENSRNOT00000068496	RGD1310819 NCBI RGD Ensembl Show fit	similar to putative protein (5S487)
chr8_+_22189600 Show fit	11.11	ENSRNOT00000061100	Pde4a NCBI RGD Ensembl Show fit	phosphodiesterase 4A
chr1_-_64405149 Show fit	11.08	ENSRNOT00000089944	Cacng7 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit gamma 7
chr9_+_20213588 Show fit	11.05	ENSRNOT00000089341	LOC100911515 NCBI RGD Ensembl Show fit	triosephosphate isomerase-like
chr3_-_111994337 Show fit	11.01	ENSRNOT00000030502	Pla2g4e NCBI RGD Ensembl Show fit	phospholipase A2, group IVE
chr3_+_48626038 Show fit	10.99	ENSRNOT00000009697	Gca NCBI RGD Ensembl Show fit	grancalcin
chr7_+_140383397 Show fit	10.96	ENSRNOT00000090760	Ccdc65 NCBI RGD Ensembl Show fit	coiled-coil domain containing 65
chr6_-_92760018 Show fit	10.93	ENSRNOT00000009560	Trim9 NCBI RGD Ensembl Show fit	tripartite motif-containing 9
chr1_+_89491654 Show fit	10.90	ENSRNOT00000028632	Lgi4 NCBI RGD Ensembl Show fit	leucine-rich repeat LGI family, member 4
chr8_-_130224444 Show fit	10.85	ENSRNOT00000026173	Lyzl4 NCBI RGD Ensembl Show fit	lysozyme-like 4
chr15_+_1054937 Show fit	10.84	ENSRNOT00000008154	AABR07016841.1 NCBI RGD Ensembl Show fit
chr7_+_18668692 Show fit	10.70	ENSRNOT00000009532	Kank3 NCBI RGD Ensembl Show fit	KN motif and ankyrin repeat domains 3
chr17_+_83221827 Show fit	10.67	ENSRNOT00000000155	Plxdc2 NCBI RGD Ensembl Show fit	plexin domain containing 2
chr1_+_40816107 Show fit	10.58	ENSRNOT00000060767	Akap12 NCBI RGD Ensembl Show fit	A-kinase anchoring protein 12
chr4_+_123801174 Show fit	10.56	ENSRNOT00000029055	RGD1560289 NCBI RGD Ensembl Show fit	similar to chromosome 3 open reading frame 20
chr10_+_13061170 Show fit	10.55	ENSRNOT00000004936	Pkmyt1 NCBI RGD Ensembl Show fit	protein kinase, membrane associated tyrosine/threonine 1
chrX_-_123788898 Show fit	10.54	ENSRNOT00000009123	Akap14 NCBI RGD Ensembl Show fit	A-kinase anchoring protein 14
chr5_+_135029955 Show fit	10.53	ENSRNOT00000074860	LOC100911669 NCBI RGD Ensembl Show fit	uncharacterized LOC100911669
chr6_-_1942972 Show fit	10.51	ENSRNOT00000048711	Cdc42ep3 NCBI RGD Ensembl Show fit	CDC42 effector protein 3
chr8_-_109621408 Show fit	10.50	ENSRNOT00000087398	Ppp2r3a NCBI RGD Ensembl Show fit	protein phosphatase 2, regulatory subunit B'', alpha
chr2_-_246737997 Show fit	10.45	ENSRNOT00000021719	Pdha2 NCBI RGD Ensembl Show fit	pyruvate dehydrogenase (lipoamide) alpha 2
chr13_-_81214494 Show fit	10.37	ENSRNOT00000004950 ENSRNOT00000082385	Prrx1 NCBI RGD Ensembl Show fit	paired related homeobox 1
chr2_-_84531192 Show fit	10.32	ENSRNOT00000065312 ENSRNOT00000090540	Ropn1l NCBI RGD Ensembl Show fit	rhophilin associated tail protein 1-like
chr8_-_53901358 Show fit	10.32	ENSRNOT00000047666 ENSRNOT00000042281	Ncam1 NCBI RGD Ensembl Show fit	neural cell adhesion molecule 1
chr1_-_170397191 Show fit	10.22	ENSRNOT00000090181	Apbb1 NCBI RGD Ensembl Show fit	amyloid beta precursor protein binding family B member 1
chr3_-_11885311 Show fit	10.21	ENSRNOT00000021189 ENSRNOT00000021178	Stxbp1 NCBI RGD Ensembl Show fit	syntaxin binding protein 1
chr17_+_5311274 Show fit	10.18	ENSRNOT00000067020	LOC102547665 NCBI RGD Ensembl Show fit	spermatogenesis-associated protein 31D1-like
chr1_+_101682172 Show fit	10.18	ENSRNOT00000028540	Car11 NCBI RGD Ensembl Show fit	carbonic anhydrase 11
chr4_-_157679962 Show fit	10.15	ENSRNOT00000050443	Gapdh NCBI RGD Ensembl Show fit	glyceraldehyde-3-phosphate dehydrogenase
chr1_-_215846911 Show fit	10.11	ENSRNOT00000089171	Igf2 NCBI RGD Ensembl Show fit	insulin-like growth factor 2
chr1_+_18491384 Show fit	10.06	ENSRNOT00000079138 ENSRNOT00000014917	Lama2 NCBI RGD Ensembl Show fit	laminin subunit alpha 2
chr19_-_62158327 Show fit	10.01	ENSRNOT00000075053	Ccdc7 NCBI RGD Ensembl Show fit	coiled-coil domain containing 7
chr19_+_56220755 Show fit	9.88	ENSRNOT00000023452	Tubb3 NCBI RGD Ensembl Show fit	tubulin, beta 3 class III
chr11_+_86552022 Show fit	9.86	ENSRNOT00000002597	Tbx1 NCBI RGD Ensembl Show fit	T-box 1
chr16_+_21050243 Show fit	9.78	ENSRNOT00000064308	Ncan NCBI RGD Ensembl Show fit	neurocan
chr5_-_58078545 Show fit	9.75	ENSRNOT00000075777	Cntfr NCBI RGD Ensembl Show fit	ciliary neurotrophic factor receptor
chr5_-_57372239 Show fit	9.72	ENSRNOT00000012975	Aqp7 NCBI RGD Ensembl Show fit	aquaporin 7
chr3_+_65672058 Show fit	9.72	ENSRNOT00000057901	RGD1564319 NCBI RGD Ensembl Show fit	similar to TF-1 apoptosis related protein 19
chr1_-_81534140 Show fit	9.69	ENSRNOT00000027202	Tex101 NCBI RGD Ensembl Show fit	testis expressed 101
chr1_-_84254645 Show fit	9.68	ENSRNOT00000077651	Sptbn4 NCBI RGD Ensembl Show fit	spectrin, beta, non-erythrocytic 4
chr5_+_122390522 Show fit	9.64	ENSRNOT00000064567	Sgip1 NCBI RGD Ensembl Show fit	SH3-domain GRB2-like (endophilin) interacting protein 1
chrX_-_38196060 Show fit	9.63	ENSRNOT00000006741 ENSRNOT00000006438	Sh3kbp1 NCBI RGD Ensembl Show fit	SH3 domain-containing kinase-binding protein 1
chr2_-_62634785 Show fit	9.57	ENSRNOT00000017937	Pdzd2 NCBI RGD Ensembl Show fit	PDZ domain containing 2
chr15_-_14737704 Show fit	9.47	ENSRNOT00000011307	Synpr NCBI RGD Ensembl Show fit	synaptoporin
chr5_-_139227196 Show fit	9.42	ENSRNOT00000050941	Foxo6 NCBI RGD Ensembl Show fit	forkhead box O6
chr4_-_157798868 Show fit	9.35	ENSRNOT00000044425	Tuba3b NCBI RGD Ensembl Show fit	tubulin, alpha 3B
chrX_-_82986051 Show fit	9.26	ENSRNOT00000077587	Hdx NCBI RGD Ensembl Show fit	highly divergent homeobox
chr2_-_45518502 Show fit	9.22	ENSRNOT00000014627	Hspb3 NCBI RGD Ensembl Show fit	heat shock protein family B (small) member 3
chr12_+_23151180 Show fit	9.20	ENSRNOT00000059486	Cux1 NCBI RGD Ensembl Show fit	cut-like homeobox 1
chr3_-_148932878 Show fit	9.09	ENSRNOT00000013881	Nol4l NCBI RGD Ensembl Show fit	nucleolar protein 4-like
chr2_+_188528979 Show fit	9.05	ENSRNOT00000087934	Thbs3 NCBI RGD Ensembl Show fit	thrombospondin 3
chr6_-_33738825 Show fit	9.05	ENSRNOT00000039492	Slc7a15 NCBI RGD Ensembl Show fit	solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chrX_+_45965301 Show fit	9.01	ENSRNOT00000005141	Fam47a NCBI RGD Ensembl Show fit	family with sequence similarity 47, member A
chr10_+_90134193 Show fit	9.00	ENSRNOT00000028375	G6pc3 NCBI RGD Ensembl Show fit	glucose 6 phosphatase catalytic subunit 3
chr19_-_37370429 Show fit	9.00	ENSRNOT00000022497	Kctd19 NCBI RGD Ensembl Show fit	potassium channel tetramerization domain containing 19
chr19_-_10360310 Show fit	8.95	ENSRNOT00000087100	Katnb1 NCBI RGD Ensembl Show fit	katanin regulatory subunit B1
chr10_-_74679858 Show fit	8.84	ENSRNOT00000003859	Ppm1e NCBI RGD Ensembl Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr2_-_189765415 Show fit	8.72	ENSRNOT00000020815	Slc27a3 NCBI RGD Ensembl Show fit	solute carrier family 27 member 3
chr7_-_140483693 Show fit	8.71	ENSRNOT00000089060	Ddn NCBI RGD Ensembl Show fit	dendrin
chr5_+_61565064 Show fit	8.65	ENSRNOT00000090186	Tdrd7 NCBI RGD Ensembl Show fit	tudor domain containing 7
chr4_+_7377563 Show fit	8.60	ENSRNOT00000084826	Kcnh2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily H member 2
chr1_-_216663720 Show fit	8.53	ENSRNOT00000078944 ENSRNOT00000077409	Cdkn1c NCBI RGD Ensembl Show fit	cyclin-dependent kinase inhibitor 1C
chr3_+_6773813 Show fit	8.47	ENSRNOT00000065953 ENSRNOT00000013443	Olfm1 NCBI RGD Ensembl Show fit	olfactomedin 1
chr20_-_5533600 Show fit	8.43	ENSRNOT00000072319	Cuta NCBI RGD Ensembl Show fit	cutA divalent cation tolerance homolog
chr1_+_102915191 Show fit	8.43	ENSRNOT00000017851	Ldhc NCBI RGD Ensembl Show fit	lactate dehydrogenase C
chr10_-_85938085 Show fit	8.31	ENSRNOT00000043561	Plxdc1 NCBI RGD Ensembl Show fit	plexin domain containing 1
chr5_-_151709877 Show fit	8.29	ENSRNOT00000080602	Trnp1 NCBI RGD Ensembl Show fit	TMF1-regulated nuclear protein 1
chr9_+_20213776 Show fit	8.24	ENSRNOT00000071439	LOC100911515 NCBI RGD Ensembl Show fit	triosephosphate isomerase-like
chr7_-_72328128 Show fit	8.18	ENSRNOT00000008227	Tspyl5 NCBI RGD Ensembl Show fit	TSPY-like 5
chr3_-_79743737 Show fit	8.14	ENSRNOT00000013584	Ptpmt1 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, mitochondrial 1
chr7_-_11777503 Show fit	8.10	ENSRNOT00000026220	Amh NCBI RGD Ensembl Show fit	anti-Mullerian hormone
chrX_-_139329975 Show fit	8.06	ENSRNOT00000086405	LOC103694517 NCBI RGD Ensembl Show fit	high mobility group protein B4-like
chrX_-_130794673 Show fit	8.03	ENSRNOT00000080612	LOC691030 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 1700001F22
chr18_-_86878142 Show fit	7.97	ENSRNOT00000058139	Dok6 NCBI RGD Ensembl Show fit	docking protein 6
chr1_+_165237847 Show fit	7.87	ENSRNOT00000022963	Pgm2l1 NCBI RGD Ensembl Show fit	phosphoglucomutase 2-like 1
chrX_+_69730242 Show fit	7.86	ENSRNOT00000075980 ENSRNOT00000076425	Eda NCBI RGD Ensembl Show fit	ectodysplasin-A
chr10_-_89084885 Show fit	7.77	ENSRNOT00000027452	Plekhh3 NCBI RGD Ensembl Show fit	pleckstrin homology, MyTH4 and FERM domain containing H3
chr5_+_108278217 Show fit	7.77	ENSRNOT00000038972	Dmrta1 NCBI RGD Ensembl Show fit	DMRT-like family A1
chr5_-_73494030 Show fit	7.76	ENSRNOT00000022291	Actl7b NCBI RGD Ensembl Show fit	actin-like 7b
chr5_-_22769907 Show fit	7.72	ENSRNOT00000047805 ENSRNOT00000076167 ENSRNOT00000076507 ENSRNOT00000076113 ENSRNOT00000083779	Asph NCBI RGD Ensembl Show fit	aspartate-beta-hydroxylase
chr7_-_31824064 Show fit	7.67	ENSRNOT00000011494 ENSRNOT00000080824	Slc25a3 NCBI RGD Ensembl Show fit	solute carrier family 25 member 3
chr7_-_115045802 Show fit	7.67	ENSRNOT00000040236 ENSRNOT00000071818	Mroh5 NCBI RGD Ensembl Show fit	maestro heat-like repeat family member 5
chr13_+_48607308 Show fit	7.65	ENSRNOT00000063882	Slc41a1 NCBI RGD Ensembl Show fit	solute carrier family 41 member 1
chr1_+_101783621 Show fit	7.64	ENSRNOT00000067679	Lmtk3 NCBI RGD Ensembl Show fit	lemur tyrosine kinase 3
chr6_-_26629654 Show fit	7.59	ENSRNOT00000031244	Dnajc5g NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member C5 gamma
chr5_+_58937615 Show fit	7.57	ENSRNOT00000080909	Tesk1 NCBI RGD Ensembl Show fit	testis-specific kinase 1
chr8_-_49045154 Show fit	7.56	ENSRNOT00000088034	Phldb1 NCBI RGD Ensembl Show fit	pleckstrin homology-like domain, family B, member 1
chr15_+_33600102 Show fit	7.55	ENSRNOT00000022664	Cmtm5 NCBI RGD Ensembl Show fit	CKLF-like MARVEL transmembrane domain containing 5
chr20_+_3555135 Show fit	7.54	ENSRNOT00000085380	Ddr1 NCBI RGD Ensembl Show fit	discoidin domain receptor tyrosine kinase 1
chr1_-_101883744 Show fit	7.49	ENSRNOT00000028635	Syngr4 NCBI RGD Ensembl Show fit	synaptogyrin 4
chr5_+_61564864 Show fit	7.46	ENSRNOT00000085738	Tdrd7 NCBI RGD Ensembl Show fit	tudor domain containing 7
chr1_-_129217058 Show fit	7.41	ENSRNOT00000086439	Pgpep1l NCBI RGD Ensembl Show fit	pyroglutamyl-peptidase I-like
chr9_+_47987 Show fit	7.38	ENSRNOT00000066582	Efhb NCBI RGD Ensembl Show fit	EF hand domain family, member B
chr7_+_128500011 Show fit	7.35	ENSRNOT00000074625	Fam19a5 NCBI RGD Ensembl Show fit	family with sequence similarity 19 member A5, C-C motif chemokine like
chr5_-_164971903 Show fit	7.33	ENSRNOT00000067059	Fbxo44 NCBI RGD Ensembl Show fit	F-box protein 44

Network of associatons between targets according to the STRING database.

First level regulatory network of Plag1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.5	52.4	GO:0031448	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
9.3	28.0	GO:0098971	anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
9.0	26.9	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
7.1	21.4	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
7.0	21.1	GO:0035544	negative regulation of SNARE complex assembly(GO:0035544)
6.7	26.6	GO:2000224	regulation of testosterone biosynthetic process(GO:2000224)
6.4	19.2	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
6.0	41.9	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
5.7	23.0	GO:2000318	positive regulation of T-helper 17 type immune response(GO:2000318)
5.7	28.3	GO:0002317	plasma cell differentiation(GO:0002317)
5.6	16.9	GO:1904057	negative regulation of sensory perception of pain(GO:1904057)
5.4	16.3	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
5.0	20.2	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
4.9	19.7	GO:0016554	cytidine to uridine editing(GO:0016554)
4.9	19.6	GO:1902856	negative regulation of nonmotile primary cilium assembly(GO:1902856)
4.5	31.2	GO:0071313	cellular response to caffeine(GO:0071313)
4.3	21.5	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) response to interleukin-9(GO:0071104)
4.3	12.9	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
3.9	11.7	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
3.6	17.9	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
3.5	10.5	GO:0090247	cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
3.4	10.3	GO:0001928	regulation of exocyst assembly(GO:0001928)
3.4	10.2	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
3.4	13.5	GO:1903596	regulation of gap junction assembly(GO:1903596)
3.3	19.8	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
3.3	61.8	GO:0006000	fructose metabolic process(GO:0006000)
3.2	15.8	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
3.0	15.1	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
3.0	12.1	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
3.0	9.0	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
2.9	11.5	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
2.9	8.6	GO:1902303	negative regulation of potassium ion export(GO:1902303)
2.8	8.4	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244)
2.8	16.6	GO:0071306	cellular response to vitamin E(GO:0071306)
2.7	8.1	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
2.5	4.9	GO:0046351	disaccharide biosynthetic process(GO:0046351)
2.4	7.3	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
2.4	7.3	GO:0071469	cellular response to alkaline pH(GO:0071469)
2.4	14.6	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
2.3	23.5	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
2.3	9.2	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
2.3	6.9	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
2.3	11.4	GO:0006842	tricarboxylic acid transport(GO:0006842)
2.3	6.8	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
2.2	6.7	GO:2000312	regulation of kainate selective glutamate receptor activity(GO:2000312)
2.2	31.4	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
2.2	4.4	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
2.2	6.5	GO:2000777	positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
2.1	6.4	GO:0048749	compound eye development(GO:0048749)
2.1	18.8	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
2.1	8.2	GO:0021590	cerebellum maturation(GO:0021590)
2.0	6.1	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
2.0	9.8	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
1.9	9.7	GO:0015793	glycerol transport(GO:0015793)
1.8	5.5	GO:1902460	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.8	7.3	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
1.8	5.5	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.8	5.4	GO:0046066	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) dGDP metabolic process(GO:0046066)
1.8	7.1	GO:1904158	axonemal central apparatus assembly(GO:1904158)
1.7	6.7	GO:0034696	response to prostaglandin F(GO:0034696)
1.7	13.4	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
1.6	9.6	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
1.5	7.7	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
1.5	9.0	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
1.5	4.4	GO:0018201	N-terminal protein amino acid methylation(GO:0006480) peptidyl-glycine modification(GO:0018201)
1.4	2.9	GO:0014826	vein smooth muscle contraction(GO:0014826)
1.4	5.7	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
1.4	8.5	GO:0023041	neuronal signal transduction(GO:0023041)
1.4	20.3	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.3	2.7	GO:0005984	disaccharide metabolic process(GO:0005984)
1.3	2.7	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
1.3	5.1	GO:1901526	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.3	6.4	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
1.3	7.7	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
1.3	5.1	GO:0044211	CTP salvage(GO:0044211)
1.3	6.3	GO:0019521	aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
1.2	13.6	GO:0060346	bone trabecula formation(GO:0060346)
1.2	4.8	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.2	3.6	GO:0002149	hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
1.2	13.0	GO:0006527	arginine catabolic process(GO:0006527)
1.2	15.2	GO:0060019	radial glial cell differentiation(GO:0060019)
1.2	19.8	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
1.2	4.7	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
1.2	8.1	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
1.2	18.6	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.2	3.5	GO:2001226	negative regulation of chloride transport(GO:2001226)
1.1	11.4	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
1.1	19.3	GO:0006098	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
1.1	3.4	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
1.1	2.2	GO:0000189	MAPK import into nucleus(GO:0000189)
1.1	3.3	GO:0021678	third ventricle development(GO:0021678)
1.1	10.8	GO:0048664	neuron fate determination(GO:0048664)
1.1	3.2	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
1.1	10.6	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
1.0	3.1	GO:0045799	positive regulation of chromatin assembly or disassembly(GO:0045799)
1.0	14.4	GO:0007256	activation of JNKK activity(GO:0007256)
1.0	7.1	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
1.0	6.1	GO:2000852	regulation of corticosterone secretion(GO:2000852)
1.0	4.0	GO:0072144	glomerular mesangial cell development(GO:0072144)
1.0	4.0	GO:2000669	negative regulation of dendritic cell apoptotic process(GO:2000669)
1.0	9.0	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
1.0	5.9	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.0	4.8	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
1.0	2.9	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.9	5.7	GO:0010045	response to nickel cation(GO:0010045)
0.9	5.5	GO:0072014	proximal tubule development(GO:0072014)
0.9	17.5	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.9	10.1	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.9	12.5	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.9	8.6	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.9	3.4	GO:0015870	acetylcholine transport(GO:0015870)
0.9	34.2	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.9	3.4	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.9	5.1	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.8	2.4	GO:1904373	response to kainic acid(GO:1904373)
0.8	5.7	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.8	1.6	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.8	1.6	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.8	3.9	GO:1902162	regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.8	3.9	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.8	5.5	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.8	7.8	GO:0060179	male mating behavior(GO:0060179)
0.8	5.4	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.8	7.5	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.7	12.4	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.7	20.3	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.7	5.1	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.7	2.2	GO:0097167	circadian regulation of translation(GO:0097167)
0.7	30.0	GO:0007340	acrosome reaction(GO:0007340)
0.7	5.5	GO:0070294	renal sodium ion absorption(GO:0070294)
0.7	11.6	GO:0001675	acrosome assembly(GO:0001675)
0.7	4.1	GO:0046836	glycolipid transport(GO:0046836)
0.7	13.5	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.7	4.7	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.7	6.0	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
0.7	29.8	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.7	2.6	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) cell differentiation involved in salivary gland development(GO:0060689)
0.6	7.0	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.6	14.6	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.6	7.6	GO:2001197	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.6	11.2	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.6	3.7	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.6	14.5	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.6	5.4	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.6	4.2	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.6	3.0	GO:0035063	nuclear speck organization(GO:0035063)
0.6	6.9	GO:0006241	CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.6	1.7	GO:1903575	cornified envelope assembly(GO:1903575)
0.6	11.1	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.6	1.7	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.5	4.4	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.5	4.9	GO:0016198	axon choice point recognition(GO:0016198)
0.5	22.7	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.5	13.7	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.5	11.1	GO:0034138	toll-like receptor 3 signaling pathway(GO:0034138)
0.5	11.1	GO:0048240	sperm capacitation(GO:0048240)
0.5	42.4	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.5	5.7	GO:0002024	diet induced thermogenesis(GO:0002024)
0.5	5.0	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.5	7.0	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.5	9.4	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.5	16.3	GO:0003009	skeletal muscle contraction(GO:0003009)
0.5	17.6	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.5	1.0	GO:0060460	left lung morphogenesis(GO:0060460)
0.5	1.0	GO:0045054	constitutive secretory pathway(GO:0045054)
0.5	0.9	GO:0007037	vacuolar phosphate transport(GO:0007037) positive regulation of parathyroid hormone secretion(GO:2000830)
0.5	6.1	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.4	4.9	GO:0002021	response to dietary excess(GO:0002021)
0.4	0.9	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.4	12.4	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.4	5.7	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.4	1.3	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.4	3.0	GO:0033182	regulation of histone ubiquitination(GO:0033182)
0.4	2.2	GO:0001661	conditioned taste aversion(GO:0001661)
0.4	9.2	GO:0097503	sialylation(GO:0097503)
0.4	4.2	GO:0007614	short-term memory(GO:0007614)
0.4	4.4	GO:0007258	JUN phosphorylation(GO:0007258)
0.4	2.4	GO:0015074	DNA integration(GO:0015074)
0.4	2.8	GO:0050915	sensory perception of sour taste(GO:0050915)
0.4	5.1	GO:0051601	exocyst localization(GO:0051601)
0.4	2.7	GO:0015871	choline transport(GO:0015871)
0.4	1.9	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4	5.4	GO:0042407	cristae formation(GO:0042407)
0.4	4.2	GO:0021670	lateral ventricle development(GO:0021670)
0.4	1.1	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.4	3.0	GO:0007512	adult heart development(GO:0007512)
0.4	27.6	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.3	7.7	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.3	1.4	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.3	5.2	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.3	0.7	GO:0071929	alpha-tubulin acetylation(GO:0071929)
0.3	6.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.3	7.0	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3	8.3	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.3	3.3	GO:0008215	spermine metabolic process(GO:0008215)
0.3	4.6	GO:0036065	fucosylation(GO:0036065)
0.3	6.8	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.3	12.6	GO:0051693	actin filament capping(GO:0051693)
0.3	13.3	GO:0043967	histone H4 acetylation(GO:0043967)
0.3	6.3	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.3	2.5	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.3	0.9	GO:0099638	endosome to plasma membrane protein transport(GO:0099638)
0.3	3.3	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.3	0.9	GO:0032423	regulation of mismatch repair(GO:0032423)
0.3	16.1	GO:1901796	regulation of signal transduction by p53 class mediator(GO:1901796)
0.3	6.5	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.3	8.2	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.3	7.5	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.3	6.7	GO:0030823	regulation of cGMP metabolic process(GO:0030823)
0.3	0.6	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.3	10.1	GO:0051058	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.3	1.7	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.3	1.7	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.3	3.7	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.3	2.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.3	13.1	GO:0046847	filopodium assembly(GO:0046847)
0.3	8.6	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.3	7.2	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3	2.7	GO:0008298	intracellular mRNA localization(GO:0008298)
0.3	0.8	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.3	6.5	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.3	4.0	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.3	4.2	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.3	15.2	GO:0046785	microtubule polymerization(GO:0046785)
0.3	9.4	GO:0048255	mRNA stabilization(GO:0048255)
0.3	3.9	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.3	10.7	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.3	9.8	GO:0007528	neuromuscular junction development(GO:0007528)
0.3	6.9	GO:0042246	tissue regeneration(GO:0042246)
0.3	33.3	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.2	2.1	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2	7.1	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.2	1.4	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.2	2.7	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.2	10.7	GO:0043462	regulation of ATPase activity(GO:0043462)
0.2	2.6	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.2	19.3	GO:1903955	positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2	3.9	GO:0032402	establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402)
0.2	11.1	GO:0019226	transmission of nerve impulse(GO:0019226)
0.2	3.2	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
0.2	5.5	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.2	3.5	GO:0048814	regulation of dendrite morphogenesis(GO:0048814)
0.2	3.4	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2	8.9	GO:0010507	negative regulation of autophagy(GO:0010507)
0.2	0.4	GO:1901374	acetate ester transport(GO:1901374)
0.2	4.2	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.2	0.4	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2	2.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.2	1.9	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
0.2	5.6	GO:0021696	cerebellar cortex morphogenesis(GO:0021696)
0.2	1.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2	1.1	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.2	1.3	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2	1.3	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.2	1.4	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.2	2.5	GO:0099517	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2	1.4	GO:0006622	protein targeting to lysosome(GO:0006622)
0.2	2.9	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.1	1.2	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052) regulation of male germ cell proliferation(GO:2000254)
0.1	5.7	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.7	GO:1903251	multi-ciliated epithelial cell differentiation(GO:1903251)
0.1	5.3	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.1	17.5	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	3.2	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	0.4	GO:0072086	specification of loop of Henle identity(GO:0072086)
0.1	2.4	GO:0001578	microtubule bundle formation(GO:0001578)
0.1	1.9	GO:0007035	vacuolar acidification(GO:0007035)
0.1	6.2	GO:0009060	aerobic respiration(GO:0009060)
0.1	1.3	GO:0036010	protein localization to endosome(GO:0036010)
0.1	4.0	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1	1.5	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1	4.0	GO:0009395	phospholipid catabolic process(GO:0009395)
0.1	0.3	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.1	5.8	GO:0035725	sodium ion transmembrane transport(GO:0035725)
0.1	0.9	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
0.1	2.2	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1	1.0	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	9.6	GO:0008360	regulation of cell shape(GO:0008360)
0.1	0.7	GO:0042711	maternal behavior(GO:0042711)
0.1	2.3	GO:0045109	intermediate filament organization(GO:0045109)
0.1	2.3	GO:0001881	receptor recycling(GO:0001881)
0.1	0.6	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.1	2.9	GO:0016239	positive regulation of macroautophagy(GO:0016239)
0.1	0.1	GO:2000328	regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1	3.4	GO:0001508	action potential(GO:0001508)
0.1	4.6	GO:0007140	male meiosis(GO:0007140)
0.1	2.4	GO:0032456	endocytic recycling(GO:0032456)
0.1	4.5	GO:0007045	cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.1	0.4	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.1	2.6	GO:0048747	muscle fiber development(GO:0048747)
0.1	1.5	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.3	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1	1.1	GO:0015732	prostaglandin transport(GO:0015732)
0.1	0.4	GO:0097062	dendritic spine maintenance(GO:0097062)
0.1	1.0	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.1	0.8	GO:0021591	ventricular system development(GO:0021591)
0.1	1.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.3	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.1	0.4	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	0.6	GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) serine phosphorylation of STAT protein(GO:0042501)
0.1	5.6	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.1	14.6	GO:0060271	cilium morphogenesis(GO:0060271)
0.1	1.9	GO:0015909	long-chain fatty acid transport(GO:0015909)
0.1	2.1	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.1	3.3	GO:0031398	positive regulation of protein ubiquitination(GO:0031398)
0.1	1.0	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.1	7.3	GO:0050803	regulation of synapse structure or activity(GO:0050803)
0.1	0.8	GO:0042749	regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0	7.6	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	1.2	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.8	GO:0006020	inositol metabolic process(GO:0006020)
0.0	5.5	GO:0006364	rRNA processing(GO:0006364)
0.0	1.4	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	1.7	GO:0015914	phospholipid transport(GO:0015914)
0.0	3.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.3	GO:0070571	negative regulation of neuron projection regeneration(GO:0070571)
0.0	0.3	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.0	0.6	GO:0003170	heart valve development(GO:0003170)
0.0	0.8	GO:1901998	toxin transport(GO:1901998)
0.0	0.5	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.0	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.3	38.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
5.3	15.8	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
4.9	14.7	GO:0097512	cardiac myofibril(GO:0097512)
4.6	13.9	GO:1902560	GMP reductase complex(GO:1902560)
4.4	26.6	GO:0042584	chromaffin granule membrane(GO:0042584)
4.0	20.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
3.8	11.5	GO:1990923	PET complex(GO:1990923)
3.7	26.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
3.5	31.2	GO:0030314	junctional membrane complex(GO:0030314)
3.4	33.7	GO:0008091	spectrin(GO:0008091)
3.3	96.3	GO:0031430	M band(GO:0031430)
3.3	9.8	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
3.1	37.7	GO:0005861	troponin complex(GO:0005861)
2.6	10.2	GO:1990761	growth cone lamellipodium(GO:1990761)
2.4	7.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
2.3	11.7	GO:0060053	neurofilament cytoskeleton(GO:0060053)
2.2	11.2	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
2.1	8.3	GO:0072487	MSL complex(GO:0072487)
2.0	28.0	GO:0035253	ciliary rootlet(GO:0035253)
1.8	7.3	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.5	6.0	GO:0032021	NELF complex(GO:0032021)
1.5	5.9	GO:0000408	EKC/KEOPS complex(GO:0000408)
1.4	11.5	GO:0033010	paranodal junction(GO:0033010)
1.4	7.1	GO:1990716	axonemal central apparatus(GO:1990716)
1.4	5.5	GO:0005956	protein kinase CK2 complex(GO:0005956)
1.3	20.1	GO:0032591	dendritic spine membrane(GO:0032591)
1.3	10.2	GO:0097452	GAIT complex(GO:0097452)
1.2	4.8	GO:0098831	presynaptic active zone cytoplasmic component(GO:0098831)
1.2	11.9	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
1.1	3.4	GO:0031372	UBC13-MMS2 complex(GO:0031372)
1.1	31.9	GO:0002080	acrosomal membrane(GO:0002080)
1.1	5.7	GO:0048476	Holliday junction resolvase complex(GO:0048476)
1.1	81.1	GO:0031594	neuromuscular junction(GO:0031594)
1.1	5.5	GO:0070695	FHF complex(GO:0070695)
1.1	14.1	GO:0097539	ciliary transition fiber(GO:0097539)
1.0	19.8	GO:0097470	ribbon synapse(GO:0097470)
1.0	10.2	GO:0048787	presynaptic active zone membrane(GO:0048787)
1.0	4.9	GO:1990393	3M complex(GO:1990393)
0.9	11.4	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.9	6.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.9	7.3	GO:0016272	prefoldin complex(GO:0016272)
0.9	22.5	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.9	7.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.9	22.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.8	2.5	GO:0060187	cell pole(GO:0060187)
0.8	8.9	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.8	16.1	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.8	5.4	GO:0061617	MICOS complex(GO:0061617)
0.8	10.5	GO:0035686	sperm fibrous sheath(GO:0035686)
0.7	3.5	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.7	2.1	GO:0044302	dentate gyrus mossy fiber(GO:0044302)
0.7	10.0	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.7	5.3	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.6	4.4	GO:0030991	intraciliary transport particle A(GO:0030991)
0.6	1.2	GO:0033186	CAF-1 complex(GO:0033186)
0.6	1.9	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.6	19.6	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.6	2.4	GO:1990745	GARP complex(GO:0000938) EARP complex(GO:1990745)
0.6	4.0	GO:0098839	postsynaptic density membrane(GO:0098839)
0.6	1.7	GO:0055087	Ski complex(GO:0055087)
0.6	21.1	GO:0048786	presynaptic active zone(GO:0048786)
0.6	12.1	GO:0060170	ciliary membrane(GO:0060170)
0.6	9.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.5	1.6	GO:0044611	nuclear pore inner ring(GO:0044611)
0.5	6.4	GO:0097542	ciliary tip(GO:0097542)
0.5	2.6	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.5	2.0	GO:0005642	annulate lamellae(GO:0005642)
0.5	7.9	GO:0018995	host(GO:0018995) host cell(GO:0043657)
0.5	3.9	GO:0005869	dynactin complex(GO:0005869)
0.5	7.6	GO:0045180	basal cortex(GO:0045180)
0.5	4.2	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.5	10.8	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.4	17.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.4	9.7	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4	12.2	GO:0035371	microtubule plus-end(GO:0035371)
0.4	6.4	GO:0030056	hemidesmosome(GO:0030056)
0.4	10.3	GO:0097225	sperm midpiece(GO:0097225)
0.4	3.7	GO:0071821	FANCM-MHF complex(GO:0071821)
0.4	7.3	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4	10.5	GO:0005605	basal lamina(GO:0005605)
0.4	1.9	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.4	39.6	GO:0030018	Z disc(GO:0030018)
0.4	30.5	GO:0016234	inclusion body(GO:0016234)
0.4	1.8	GO:0035976	AP1 complex(GO:0035976)
0.4	3.9	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.3	34.9	GO:0034705	potassium channel complex(GO:0034705)
0.3	3.1	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3	8.1	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.3	31.8	GO:0031225	anchored component of membrane(GO:0031225)
0.3	6.1	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.3	2.8	GO:0042788	polysomal ribosome(GO:0042788)
0.3	5.5	GO:0030131	clathrin adaptor complex(GO:0030131)
0.3	4.8	GO:0000930	gamma-tubulin complex(GO:0000930)
0.3	3.6	GO:0032426	stereocilium tip(GO:0032426)
0.3	17.9	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3	2.8	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.3	18.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.3	12.4	GO:0016592	mediator complex(GO:0016592)
0.3	1.6	GO:0032009	early phagosome(GO:0032009)
0.3	24.0	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.3	3.6	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2	1.4	GO:0032585	multivesicular body membrane(GO:0032585)
0.2	6.4	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.2	25.7	GO:0031514	motile cilium(GO:0031514)
0.2	0.7	GO:0097427	microtubule bundle(GO:0097427)
0.2	4.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.2	2.2	GO:0031143	pseudopodium(GO:0031143)
0.2	5.1	GO:0000145	exocyst(GO:0000145)
0.2	30.5	GO:0008021	synaptic vesicle(GO:0008021)
0.2	5.0	GO:0005905	clathrin-coated pit(GO:0005905)
0.2	6.9	GO:0005844	polysome(GO:0005844)
0.2	4.9	GO:0032420	stereocilium(GO:0032420)
0.2	4.1	GO:0005640	nuclear outer membrane(GO:0005640)
0.2	1.6	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2	6.4	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2	7.9	GO:0016459	myosin complex(GO:0016459)
0.2	3.6	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2	5.3	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287)
0.2	3.5	GO:1902711	GABA-A receptor complex(GO:1902711)
0.2	1.3	GO:0000815	ESCRT III complex(GO:0000815)
0.2	4.6	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2	7.3	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.2	57.2	GO:0005635	nuclear envelope(GO:0005635)
0.1	3.6	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	9.1	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	20.3	GO:0030426	growth cone(GO:0030426)
0.1	0.8	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	1.0	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	3.0	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.1	3.1	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	0.4	GO:0005687	U4 snRNP(GO:0005687)
0.1	1.0	GO:0005833	hemoglobin complex(GO:0005833)
0.1	1.5	GO:0005682	U5 snRNP(GO:0005682)
0.1	5.0	GO:0036064	ciliary basal body(GO:0036064)
0.1	3.4	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	0.8	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1	7.2	GO:0043204	perikaryon(GO:0043204)
0.1	6.3	GO:0030139	endocytic vesicle(GO:0030139)
0.1	23.0	GO:0005815	microtubule organizing center(GO:0005815)
0.1	7.1	GO:0097060	synaptic membrane(GO:0097060)
0.0	1.4	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.3	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	1.6	GO:0000795	synaptonemal complex(GO:0000795)
0.0	1.1	GO:0015030	Cajal body(GO:0015030)
0.0	2.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.3	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.8	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.0	0.6	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.2	GO:0019013	viral nucleocapsid(GO:0019013)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.8	31.2	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
6.7	20.1	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
6.4	19.3	GO:0004807	triose-phosphate isomerase activity(GO:0004807)
6.3	38.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
5.8	40.8	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
5.4	37.7	GO:0031014	troponin T binding(GO:0031014)
5.3	26.6	GO:0030348	syntaxin-3 binding(GO:0030348)
4.9	9.8	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
4.6	13.9	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
4.5	13.5	GO:0070573	bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
4.5	26.9	GO:0005324	long-chain fatty acid transporter activity(GO:0005324) oleic acid binding(GO:0070538)
4.4	17.6	GO:0004687	myosin light chain kinase activity(GO:0004687)
4.3	13.0	GO:0016403	dimethylargininase activity(GO:0016403)
4.3	29.8	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
4.0	12.0	GO:0000827	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827)
3.9	11.8	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
3.8	19.2	GO:0070052	collagen V binding(GO:0070052)
3.8	11.4	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
3.6	14.4	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
3.3	19.7	GO:0004126	cytidine deaminase activity(GO:0004126)
3.2	9.7	GO:0015254	glycerol channel activity(GO:0015254)
3.0	11.9	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.9	20.5	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
2.9	11.5	GO:0034584	piRNA binding(GO:0034584)
2.7	27.0	GO:0050693	LBD domain binding(GO:0050693)
2.7	26.8	GO:0031432	titin binding(GO:0031432)
2.6	15.8	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
2.5	10.2	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
2.5	15.2	GO:0042289	MHC class II protein binding(GO:0042289)
2.4	7.3	GO:0097603	temperature-gated ion channel activity(GO:0097603)
2.3	9.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
2.3	11.4	GO:0015142	tricarboxylic acid transmembrane transporter activity(GO:0015142)
2.2	102.9	GO:0008307	structural constituent of muscle(GO:0008307)
2.2	6.5	GO:0042903	tubulin deacetylase activity(GO:0042903)
2.1	47.0	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
2.1	8.4	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
2.0	43.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
1.9	20.9	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.9	5.6	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
1.8	5.5	GO:0035939	microsatellite binding(GO:0035939)
1.8	5.4	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
1.8	14.5	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
1.8	9.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.8	12.5	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
1.8	28.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.7	6.9	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
1.7	5.1	GO:0016882	cyclo-ligase activity(GO:0016882)
1.6	6.4	GO:0010465	nerve growth factor receptor activity(GO:0010465) G-protein coupled neurotensin receptor activity(GO:0016492)
1.5	10.8	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.5	17.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
1.5	4.4	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
1.4	6.8	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
1.3	25.8	GO:0004697	protein kinase C activity(GO:0004697)
1.3	5.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
1.2	9.9	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
1.2	3.6	GO:0030156	benzodiazepine receptor binding(GO:0030156)
1.2	4.7	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.1	5.7	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
1.1	4.5	GO:0050682	AF-2 domain binding(GO:0050682)
1.1	32.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
1.1	7.5	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
1.1	6.5	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
1.1	17.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.0	6.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.0	4.1	GO:0017089	glycolipid transporter activity(GO:0017089)
1.0	9.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.0	5.1	GO:0004849	uridine kinase activity(GO:0004849)
1.0	13.2	GO:0019841	retinol binding(GO:0019841)
1.0	5.9	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.0	8.7	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
1.0	2.9	GO:0031708	endothelin B receptor binding(GO:0031708)
1.0	24.1	GO:0030506	ankyrin binding(GO:0030506)
1.0	2.9	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.9	2.8	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.9	2.7	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.9	5.3	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.8	10.9	GO:0003796	lysozyme activity(GO:0003796)
0.8	21.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.8	3.8	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.7	3.0	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.7	32.1	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.7	10.6	GO:0008179	adenylate cyclase binding(GO:0008179)
0.7	5.6	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.7	14.7	GO:0005123	death receptor binding(GO:0005123)
0.7	6.0	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.7	8.5	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.7	7.9	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.7	6.5	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.6	6.4	GO:0034511	U3 snoRNA binding(GO:0034511)
0.6	2.5	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.6	2.5	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.6	11.1	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.6	6.3	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.5	18.7	GO:0001540	beta-amyloid binding(GO:0001540)
0.5	82.4	GO:0044325	ion channel binding(GO:0044325)
0.5	5.5	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.5	2.7	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.5	2.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.5	11.0	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.5	1.0	GO:0061665	SUMO ligase activity(GO:0061665)
0.5	4.6	GO:0097100	supercoiled DNA binding(GO:0097100)
0.5	12.9	GO:0070840	dynein complex binding(GO:0070840)
0.5	3.5	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.5	7.3	GO:0051787	misfolded protein binding(GO:0051787)
0.5	3.4	GO:0050700	LIM domain binding(GO:0030274) CARD domain binding(GO:0050700)
0.5	1.4	GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.5	1.9	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.5	12.8	GO:0030332	cyclin binding(GO:0030332)
0.4	7.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.4	4.0	GO:0032036	myosin heavy chain binding(GO:0032036)
0.4	2.7	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4	3.5	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.4	1.3	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
0.4	32.9	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.4	14.4	GO:0042805	actinin binding(GO:0042805)
0.4	6.1	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.4	5.7	GO:0042043	neurexin family protein binding(GO:0042043)
0.4	4.4	GO:0008432	JUN kinase binding(GO:0008432)
0.4	10.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.4	4.7	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.4	8.5	GO:0003746	translation elongation factor activity(GO:0003746)
0.4	2.3	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.4	3.7	GO:0019966	interleukin-1 binding(GO:0019966)
0.4	10.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.4	4.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.4	21.1	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.4	3.2	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.3	7.2	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.3	8.5	GO:0071837	HMG box domain binding(GO:0071837)
0.3	2.3	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.3	85.6	GO:0005096	GTPase activator activity(GO:0005096)
0.3	1.6	GO:0045322	unmethylated CpG binding(GO:0045322)
0.3	3.5	GO:0008046	axon guidance receptor activity(GO:0008046)
0.3	2.8	GO:0008494	translation activator activity(GO:0008494)
0.3	6.1	GO:0008199	ferric iron binding(GO:0008199)
0.3	8.4	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3	10.3	GO:0045182	translation regulator activity(GO:0045182)
0.3	4.6	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.3	43.7	GO:0003714	transcription corepressor activity(GO:0003714)
0.3	5.8	GO:0005272	sodium channel activity(GO:0005272)
0.2	6.2	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.2	7.6	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.2	15.6	GO:0005507	copper ion binding(GO:0005507)
0.2	2.4	GO:0050321	tau-protein kinase activity(GO:0050321)
0.2	4.9	GO:0046875	ephrin receptor binding(GO:0046875)
0.2	1.0	GO:0070697	activin receptor binding(GO:0070697)
0.2	7.0	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2	0.4	GO:0005277	acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.2	8.1	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.2	49.0	GO:0015631	tubulin binding(GO:0015631)
0.2	0.6	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2	4.6	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	7.7	GO:0015296	anion:cation symporter activity(GO:0015296)
0.1	2.9	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	1.7	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	3.9	GO:0030507	spectrin binding(GO:0030507)
0.1	4.0	GO:0015491	cation:cation antiporter activity(GO:0015491)
0.1	0.8	GO:0070410	co-SMAD binding(GO:0070410)
0.1	5.6	GO:0051018	protein kinase A binding(GO:0051018)
0.1	0.9	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	11.0	GO:0047485	protein N-terminus binding(GO:0047485)
0.1	1.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.7	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	1.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.1	9.6	GO:0000149	SNARE binding(GO:0000149)
0.1	0.4	GO:0030621	U4 snRNA binding(GO:0030621)
0.1	1.8	GO:0005112	Notch binding(GO:0005112)
0.1	1.0	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	1.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	2.2	GO:0004707	MAP kinase activity(GO:0004707)
0.1	3.6	GO:0004601	peroxidase activity(GO:0004601)
0.1	8.1	GO:0016503	pheromone receptor activity(GO:0016503)
0.1	3.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	4.7	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.1	1.6	GO:0015288	porin activity(GO:0015288)
0.1	4.9	GO:0019887	protein kinase regulator activity(GO:0019887)
0.1	0.4	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	0.6	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	3.7	GO:0003724	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1	19.8	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.1	0.7	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	3.0	GO:0019003	GDP binding(GO:0019003)
0.0	1.7	GO:0005109	frizzled binding(GO:0005109)
0.0	0.6	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	18.1	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	3.1	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	1.1	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.5	GO:0070412	R-SMAD binding(GO:0070412)
0.0	2.5	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.7	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.9	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	1.3	GO:0019199	transmembrane receptor protein tyrosine kinase activity(GO:0004714) transmembrane receptor protein kinase activity(GO:0019199)
0.0	0.8	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.5	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0019209	kinase activator activity(GO:0019209)
0.0	0.3	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.3	GO:0099516	ion antiporter activity(GO:0099516)
0.0	0.8	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.0	0.3	GO:0005080	protein kinase C binding(GO:0005080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	16.7	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.9	27.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.9	31.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.9	34.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.8	14.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.7	13.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7	18.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.7	43.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.7	8.1	PID ALK2 PATHWAY	ALK2 signaling events
0.7	24.6	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.7	50.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.7	10.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.5	16.1	PID AURORA A PATHWAY	Aurora A signaling
0.5	24.4	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.5	10.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.4	26.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.4	15.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.4	14.7	PID AURORA B PATHWAY	Aurora B signaling
0.4	19.2	NABA COLLAGENS	Genes encoding collagen proteins
0.4	6.3	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.4	8.6	PID EPHB FWD PATHWAY	EPHB forward signaling
0.4	23.3	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.3	3.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3	2.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.3	4.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.3	19.5	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.3	10.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.3	17.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.3	4.4	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.2	2.2	PID EPO PATHWAY	EPO signaling pathway
0.2	6.4	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.2	9.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.2	3.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.2	3.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	29.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2	6.4	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.2	5.0	PID FGF PATHWAY	FGF signaling pathway
0.2	6.0	PID P53 REGULATION PATHWAY	p53 pathway
0.2	3.1	PID RAS PATHWAY	Regulation of Ras family activation
0.2	3.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	6.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	3.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	5.0	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	4.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	1.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	4.2	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	2.0	PID ATR PATHWAY	ATR signaling pathway
0.0	0.8	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.8	PID BMP PATHWAY	BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.0	41.6	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
2.8	110.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
1.7	8.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.6	62.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
1.5	21.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.2	13.9	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
1.1	39.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
1.1	19.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
1.0	29.8	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
1.0	50.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.9	28.0	REACTOME KINESINS	Genes involved in Kinesins
0.9	13.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.8	12.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.8	9.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.8	12.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.7	27.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.7	10.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.6	9.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6	7.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.5	33.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.5	6.1	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.5	7.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.5	6.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.5	8.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.4	2.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.4	9.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4	11.0	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.4	17.7	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.3	4.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.3	7.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.3	5.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.3	13.3	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.3	3.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.3	4.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.3	6.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	3.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	3.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	4.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.2	1.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2	2.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2	6.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	3.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	1.6	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2	3.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.2	5.1	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.2	5.0	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.2	3.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	4.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	9.1	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.2	0.5	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.2	1.9	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.1	17.9	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1	1.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	1.3	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	2.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.1	3.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	7.4	REACTOME TRANSLATION	Genes involved in Translation
0.1	3.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.9	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	8.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	0.4	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	0.8	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	1.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	0.9	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	0.3	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	5.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	2.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	0.5	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	1.5	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	1.9	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.7	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions

Results for Plag1

Z-value: 1.28

Motif logo

Transcription factors associated with Plag1

Activity-expression correlation:

Activity profile of Plag1 motif

Sorted Z-values of Plag1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Plag1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: