ISMARA results: Pou1f1

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Pou1f1

Z-value: 2.14

Motif logo

Transcription factors associated with Pou1f1

Gene Symbol	Gene ID	Gene Info
Pou1f1 NCBI RGD Ensembl	ENSRNOG00000000715	POU class 1 homeobox 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Pou1f1	rn6_v1_chr11_+_2645865_2645865	-0.48	7.1e-20	Click!

Activity profile of Pou1f1 motif

Sorted Z-values of Pou1f1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr14_+_22724399 Show fit	60.66	ENSRNOT00000002724	Ugt2b10 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase 2 family, polypeptide B10
chr1_-_148119857 Show fit	56.89	ENSRNOT00000040325	LOC100361547 NCBI RGD Ensembl Show fit	Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr1_+_147713892 Show fit	46.49	ENSRNOT00000092985 ENSRNOT00000054742 ENSRNOT00000074103	Cyp2c6v1 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
chr6_-_127816055 Show fit	42.70	ENSRNOT00000013175	Serpina3m NCBI RGD Ensembl Show fit	serine (or cysteine) proteinase inhibitor, clade A, member 3M
chr3_-_63836017 Show fit	42.12	ENSRNOT00000030978	AABR07052585.1 NCBI RGD Ensembl Show fit
chr1_-_76722965 Show fit	41.28	ENSRNOT00000052129	LOC100912485 NCBI RGD Ensembl Show fit	alcohol sulfotransferase-like
chr10_+_53781239 Show fit	40.07	ENSRNOT00000082871	Myh2 NCBI RGD Ensembl Show fit	myosin heavy chain 2
chr1_+_83163079 Show fit	37.99	ENSRNOT00000077725 ENSRNOT00000034845	Cyp2b3 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily b, polypeptide 3
chr1_-_76614279 Show fit	37.97	ENSRNOT00000041367 ENSRNOT00000089371	LOC100912485 NCBI RGD Ensembl Show fit	alcohol sulfotransferase-like
chr17_+_32973695 Show fit	36.31	ENSRNOT00000065674	RGD1565323 NCBI RGD Ensembl Show fit	similar to OTTMUSP00000000621
chr14_+_22806132 Show fit	35.99	ENSRNOT00000002728	Ugt2b10 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase 2 family, polypeptide B10
chr14_+_22517774 Show fit	35.91	ENSRNOT00000047655	Ugt2b37 NCBI RGD Ensembl Show fit	UDP-glucuronosyltransferase 2 family, member 37
chr2_-_216443518 Show fit	34.83	ENSRNOT00000022496	Amy1a NCBI RGD Ensembl Show fit	amylase, alpha 1A
chr16_+_54153054 Show fit	33.24	ENSRNOT00000090644 ENSRNOT00000014248	Fgl1 NCBI RGD Ensembl Show fit	fibrinogen-like 1
chr11_+_7265828 Show fit	31.62	ENSRNOT00000084765	Gbe1 NCBI RGD Ensembl Show fit	1,4-alpha-glucan branching enzyme 1
chr4_+_109497962 Show fit	31.41	ENSRNOT00000057869	Reg1a NCBI RGD Ensembl Show fit	regenerating family member 1 alpha
chr4_-_129619142 Show fit	31.27	ENSRNOT00000047453	Lmod3 NCBI RGD Ensembl Show fit	leiomodin 3
chr14_-_115052450 Show fit	29.81	ENSRNOT00000067998	Acyp2 NCBI RGD Ensembl Show fit	acylphosphatase 2
chr5_-_77408323 Show fit	29.69	ENSRNOT00000046857 ENSRNOT00000046760	LOC259245 NCBI RGD Ensembl Show fit Mup4 NCBI RGD Ensembl Show fit	alpha-2u globulin PGCL5 major urinary protein 4
chr1_-_76517134 Show fit	29.02	ENSRNOT00000064593 ENSRNOT00000085775	LOC100912485 NCBI RGD Ensembl Show fit	alcohol sulfotransferase-like
chr10_+_96639924 Show fit	28.01	ENSRNOT00000004756	Apoh NCBI RGD Ensembl Show fit	apolipoprotein H
chr14_+_22251499 Show fit	26.91	ENSRNOT00000087991 ENSRNOT00000002705	Ugt2a1 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase 2 family, polypeptide A1
chr3_-_37803112 Show fit	26.63	ENSRNOT00000059461	Neb NCBI RGD Ensembl Show fit	nebulin
chr13_-_56958549 Show fit	26.06	ENSRNOT00000017293 ENSRNOT00000083912	RGD1564614 NCBI RGD Ensembl Show fit	similar to complement factor H-related protein
chr4_-_41212072 Show fit	25.77	ENSRNOT00000085596	Ppp1r3a NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory subunit 3A
chr13_-_56693968 Show fit	24.64	ENSRNOT00000060160	AABR07021096.1 NCBI RGD Ensembl Show fit
chr4_-_70747226 Show fit	23.71	ENSRNOT00000044960	LOC102554637 NCBI RGD Ensembl Show fit	anionic trypsin-2-like
chr2_-_216348194 Show fit	23.47	ENSRNOT00000087839	LOC103689940 NCBI RGD Ensembl Show fit	pancreatic alpha-amylase-like
chr2_-_248484100 Show fit	23.36	ENSRNOT00000040856	Gbp3 NCBI RGD Ensembl Show fit	guanylate binding protein 3
chr14_+_22375955 Show fit	23.21	ENSRNOT00000063915 ENSRNOT00000034784	Ugt2b37 NCBI RGD Ensembl Show fit	UDP-glucuronosyltransferase 2 family, member 37
chr5_-_77316764 Show fit	23.06	ENSRNOT00000071395 ENSRNOT00000076464	Mup4 NCBI RGD Ensembl Show fit	major urinary protein 4
chr5_+_90338795 Show fit	22.85	ENSRNOT00000077864 ENSRNOT00000058882	LOC298139 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 2310003M01
chr7_-_138483612 Show fit	22.65	ENSRNOT00000085620	Slc38a4 NCBI RGD Ensembl Show fit	solute carrier family 38, member 4
chr5_-_77342299 Show fit	22.59	ENSRNOT00000075994	RGD1566134 NCBI RGD Ensembl Show fit	similar to alpha-2u-globulin
chr7_+_2689501 Show fit	22.53	ENSRNOT00000041341	Apof NCBI RGD Ensembl Show fit	apolipoprotein F
chr1_-_258766881 Show fit	22.41	ENSRNOT00000015801	Cyp2c12 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 12
chr1_+_148240504 Show fit	21.43	ENSRNOT00000085373	LOC100361547 NCBI RGD Ensembl Show fit	Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr19_+_27404712 Show fit	21.27	ENSRNOT00000023657	Mylk3 NCBI RGD Ensembl Show fit	myosin light chain kinase 3
chr4_+_70614524 Show fit	21.21	ENSRNOT00000041100	Prss3 NCBI RGD Ensembl Show fit	protease, serine 3
chr1_+_83744238 Show fit	21.20	ENSRNOT00000028249	Cyp2a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily a, polypeptide 1
chr17_+_33028293 Show fit	20.46	ENSRNOT00000072764	Mylk4 NCBI RGD Ensembl Show fit	myosin light chain kinase family, member 4
chr1_-_275882444 Show fit	20.08	ENSRNOT00000083215	Gpam NCBI RGD Ensembl Show fit	glycerol-3-phosphate acyltransferase, mitochondrial
chr18_+_56193978 Show fit	19.56	ENSRNOT00000041533 ENSRNOT00000080177	Camk2a NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase II alpha
chr8_+_52753011 Show fit	19.44	ENSRNOT00000047264	Nxpe1 NCBI RGD Ensembl Show fit	neurexophilin and PC-esterase domain family, member 1
chr6_+_127946686 Show fit	19.41	ENSRNOT00000082680	LOC500712 NCBI RGD Ensembl Show fit	Ab1-233
chr2_-_227207584 Show fit	19.20	ENSRNOT00000065361 ENSRNOT00000080215	Myoz2 NCBI RGD Ensembl Show fit	myozenin 2
chrX_-_110232179 Show fit	19.19	ENSRNOT00000014739	Serpina7 NCBI RGD Ensembl Show fit	serpin family A member 7
chr1_-_258877045 Show fit	18.97	ENSRNOT00000071633	Cyp2c13 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 13
chr4_-_70628470 Show fit	18.96	ENSRNOT00000029319	Try5 NCBI RGD Ensembl Show fit	trypsin 5
chr1_+_229030233 Show fit	18.70	ENSRNOT00000084503	Glyatl1 NCBI RGD Ensembl Show fit	glycine-N-acyltransferase-like 1
chr14_+_26662965 Show fit	18.67	ENSRNOT00000002621	Tecrl NCBI RGD Ensembl Show fit	trans-2,3-enoyl-CoA reductase-like
chr6_-_47890033 Show fit	18.59	ENSRNOT00000011290	Colec11 NCBI RGD Ensembl Show fit	collectin sub-family member 11
chr18_-_15540177 Show fit	18.47	ENSRNOT00000022113	Ttr NCBI RGD Ensembl Show fit	transthyretin
chr20_+_26999795 Show fit	18.38	ENSRNOT00000057872	Mypn NCBI RGD Ensembl Show fit	myopalladin
chr5_-_19368431 Show fit	18.34	ENSRNOT00000012819	Cyp7a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 7, subfamily a, polypeptide 1
chr17_+_72160735 Show fit	18.18	ENSRNOT00000038817	Itih2 NCBI RGD Ensembl Show fit	inter-alpha-trypsin inhibitor heavy chain 2
chr2_+_74360622 Show fit	18.04	ENSRNOT00000014013	Cdh18 NCBI RGD Ensembl Show fit	cadherin 18
chr1_+_248723397 Show fit	17.84	ENSRNOT00000072188	LOC100911854 NCBI RGD Ensembl Show fit	mannose-binding protein C-like
chr2_+_88217188 Show fit	17.77	ENSRNOT00000014267	Car1 NCBI RGD Ensembl Show fit	carbonic anhydrase I
chr4_+_14109864 Show fit	17.58	ENSRNOT00000076349	RGD1565355 NCBI RGD Ensembl Show fit	similar to fatty acid translocase/CD36
chr6_-_128003418 Show fit	17.55	ENSRNOT00000013896	Serpina3c NCBI RGD Ensembl Show fit	serine (or cysteine) proteinase inhibitor, clade A, member 3C
chr6_+_128048099 Show fit	17.52	ENSRNOT00000084685 ENSRNOT00000087017	LOC500712 NCBI RGD Ensembl Show fit	Ab1-233
chr2_+_147496229 Show fit	17.45	ENSRNOT00000022105	Tm4sf4 NCBI RGD Ensembl Show fit	transmembrane 4 L six family member 4
chr7_-_14435967 Show fit	17.24	ENSRNOT00000074801	Pglyrp2 NCBI RGD Ensembl Show fit	peptidoglycan recognition protein 2
chr1_+_106896790 Show fit	17.08	ENSRNOT00000042952 ENSRNOT00000064193	Ano5 NCBI RGD Ensembl Show fit	anoctamin 5
chrX_+_110233170 Show fit	16.76	ENSRNOT00000036019	4930513O06Rik NCBI RGD Ensembl Show fit	RIKEN cDNA 4930513O06 gene
chr2_+_227080924 Show fit	16.72	ENSRNOT00000029871	Fabp2 NCBI RGD Ensembl Show fit	fatty acid binding protein 2
chr9_-_4327679 Show fit	16.69	ENSRNOT00000073468	LOC100910235 NCBI RGD Ensembl Show fit	sulfotransferase 1C1-like
chr1_-_76780230 Show fit	16.66	ENSRNOT00000002046	LOC100912485 NCBI RGD Ensembl Show fit	alcohol sulfotransferase-like
chr20_-_28263037 Show fit	16.48	ENSRNOT00000030348	Edar NCBI RGD Ensembl Show fit	ectodysplasin-A receptor
chr4_-_13878126 Show fit	16.47	ENSRNOT00000007032	Gnat3 NCBI RGD Ensembl Show fit	G protein subunit alpha transducin 3
chr4_+_70755795 Show fit	16.38	ENSRNOT00000043527	LOC683849 NCBI RGD Ensembl Show fit	similar to Anionic trypsin II precursor (Pretrypsinogen II)
chr13_-_56763981 Show fit	16.23	ENSRNOT00000087916	LOC100361907 NCBI RGD Ensembl Show fit	complement factor H-related protein B
chr15_-_23969011 Show fit	15.72	ENSRNOT00000014821	Gch1 NCBI RGD Ensembl Show fit	GTP cyclohydrolase 1
chr4_+_70689737 Show fit	15.67	ENSRNOT00000018852	Prss2 NCBI RGD Ensembl Show fit	protease, serine, 2
chr6_-_23291568 Show fit	15.59	ENSRNOT00000085708	Clip4 NCBI RGD Ensembl Show fit	CAP-GLY domain containing linker protein family, member 4
chr14_+_22072024 Show fit	15.57	ENSRNOT00000002680	ste2 NCBI RGD Ensembl Show fit	estrogen sulfotransferase
chr10_+_70262361 Show fit	15.48	ENSRNOT00000064625 ENSRNOT00000076973	Unc45b NCBI RGD Ensembl Show fit	unc-45 myosin chaperone B
chr1_+_137860946 Show fit	15.39	ENSRNOT00000031334	Agbl1 NCBI RGD Ensembl Show fit	ATP/GTP binding protein-like 1
chr18_+_35574002 Show fit	15.38	ENSRNOT00000093442 ENSRNOT00000070817 ENSRNOT00000093356	Myot NCBI RGD Ensembl Show fit	myotilin
chr3_-_7141522 Show fit	15.35	ENSRNOT00000014572	Cel NCBI RGD Ensembl Show fit	carboxyl ester lipase
chr19_-_41686229 Show fit	15.16	ENSRNOT00000022721	Tat NCBI RGD Ensembl Show fit	tyrosine aminotransferase
chr5_-_77492013 Show fit	15.10	ENSRNOT00000012293	LOC259245 NCBI RGD Ensembl Show fit	alpha-2u globulin PGCL5
chrX_-_13601069 Show fit	15.07	ENSRNOT00000004686	Otc NCBI RGD Ensembl Show fit	ornithine carbamoyltransferase
chr14_-_1791636 Show fit	15.05	ENSRNOT00000072859	Vom2r73 NCBI RGD Ensembl Show fit	vomeronasal 2 receptor, 73
chr9_+_37749059 Show fit	15.00	ENSRNOT00000071970	LOC100909868 NCBI RGD Ensembl Show fit	myotilin-like
chr1_+_248428099 Show fit	14.90	ENSRNOT00000050984	Mbl2 NCBI RGD Ensembl Show fit	mannose binding lectin 2
chr15_-_34550850 Show fit	14.88	ENSRNOT00000027794 ENSRNOT00000090228	Cbln3 NCBI RGD Ensembl Show fit	cerebellin 3 precursor
chr4_+_154391647 Show fit	14.85	ENSRNOT00000081488 ENSRNOT00000079192	Mug1 NCBI RGD Ensembl Show fit	murinoglobulin 1
chrM_+_7758 Show fit	14.85	ENSRNOT00000046201	Mt-atp8 NCBI RGD Ensembl Show fit	mitochondrially encoded ATP synthase 8
chr1_-_116919269 Show fit	14.81	ENSRNOT00000035149	AABR07003616.1 NCBI RGD Ensembl Show fit
chr1_+_107262659 Show fit	14.67	ENSRNOT00000022499	Gas2 NCBI RGD Ensembl Show fit	growth arrest-specific 2
chr10_+_53713938 Show fit	14.63	ENSRNOT00000004236 ENSRNOT00000086599 ENSRNOT00000085582	Myh2 NCBI RGD Ensembl Show fit	myosin heavy chain 2
chr2_-_173668555 Show fit	14.60	ENSRNOT00000013452	Serpini2 NCBI RGD Ensembl Show fit	serpin family I member 2
chr3_+_54253949 Show fit	14.27	ENSRNOT00000010018	B3galt1 NCBI RGD Ensembl Show fit	Beta-1,3-galactosyltransferase 1
chr9_-_79530821 Show fit	14.25	ENSRNOT00000085619	Mreg NCBI RGD Ensembl Show fit	melanoregulin
chr18_-_62476700 Show fit	14.09	ENSRNOT00000048429	Cycs NCBI RGD Ensembl Show fit	cytochrome c, somatic
chr8_-_111777602 Show fit	13.97	ENSRNOT00000052317 ENSRNOT00000083855	RGD1310507 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 1300017J02
chr7_-_29171783 Show fit	13.96	ENSRNOT00000079235	Mybpc1 NCBI RGD Ensembl Show fit	myosin binding protein C, slow type
chr7_+_38858062 Show fit	13.90	ENSRNOT00000006234	Kera NCBI RGD Ensembl Show fit	keratocan
chr1_-_258875572 Show fit	13.90	ENSRNOT00000093005	Cyp2c13 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 13
chr9_+_74124016 Show fit	13.84	ENSRNOT00000019023	Cps1 NCBI RGD Ensembl Show fit	carbamoyl-phosphate synthase 1
chr3_-_74815509 Show fit	13.82	ENSRNOT00000045173	Olr499 NCBI RGD Ensembl Show fit	olfactory receptor 499
chr14_+_22724070 Show fit	13.79	ENSRNOT00000089471	Ugt2b10 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase 2 family, polypeptide B10
chr8_-_77398156 Show fit	13.79	ENSRNOT00000091858 ENSRNOT00000085349 ENSRNOT00000082763	Lipc NCBI RGD Ensembl Show fit	lipase C, hepatic type
chr4_+_166833320 Show fit	13.68	ENSRNOT00000031438	Tas2r120 NCBI RGD Ensembl Show fit	taste receptor, type 2, member 120
chr2_-_211017778 Show fit	13.66	ENSRNOT00000026883	Sypl2 NCBI RGD Ensembl Show fit	synaptophysin-like 2
chr17_-_69827112 Show fit	13.65	ENSRNOT00000023835	Akr1c14 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C14
chr16_+_25773602 Show fit	13.61	ENSRNOT00000047750	Gapdh-ps2 NCBI RGD Ensembl Show fit	glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr2_+_54466280 Show fit	13.41	ENSRNOT00000033112	C6 NCBI RGD Ensembl Show fit	complement C6
chr9_+_119353840 Show fit	13.37	ENSRNOT00000085362	Myom1 NCBI RGD Ensembl Show fit	myomesin 1
chr6_-_138507135 Show fit	13.31	ENSRNOT00000071078	AABR07065640.1 NCBI RGD Ensembl Show fit
chr14_-_19132208 Show fit	13.24	ENSRNOT00000060535	Afm NCBI RGD Ensembl Show fit	afamin
chr16_+_39909270 Show fit	13.19	ENSRNOT00000081994	Wdr17 NCBI RGD Ensembl Show fit	WD repeat domain 17
chr14_-_62595854 Show fit	13.19	ENSRNOT00000003024	Yipf7 NCBI RGD Ensembl Show fit	Yip1 domain family, member 7
chr5_+_165465095 Show fit	13.16	ENSRNOT00000031978	LOC691354 NCBI RGD Ensembl Show fit	hypothetical protein LOC691354
chr8_+_58431407 Show fit	13.15	ENSRNOT00000011974	Sln NCBI RGD Ensembl Show fit	sarcolipin
chr1_+_65576535 Show fit	13.09	ENSRNOT00000026575	Slc27a5 NCBI RGD Ensembl Show fit	solute carrier family 27 member 5
chr19_+_14835822 Show fit	12.97	ENSRNOT00000072804	1700007B14Rik NCBI RGD Ensembl Show fit	RIKEN cDNA 1700007B14 gene
chr2_+_22950018 Show fit	12.95	ENSRNOT00000071804	Homer1 NCBI RGD Ensembl Show fit	homer scaffolding protein 1
chr15_-_49505553 Show fit	12.90	ENSRNOT00000028974	Adamdec1 NCBI RGD Ensembl Show fit	ADAM-like, decysin 1
chrM_+_11736 Show fit	12.84	ENSRNOT00000048767	Mt-nd5 NCBI RGD Ensembl Show fit	mitochondrially encoded NADH dehydrogenase 5
chr4_+_154215250 Show fit	12.68	ENSRNOT00000072465	Mug2 NCBI RGD Ensembl Show fit	murinoglobulin 2
chr14_+_84282073 Show fit	12.57	ENSRNOT00000078271	Sec14l4 NCBI RGD Ensembl Show fit	SEC14-like lipid binding 4
chr13_+_91481461 Show fit	12.53	ENSRNOT00000012103	Olr1576 NCBI RGD Ensembl Show fit	olfactory receptor 1576
chr7_-_3805023 Show fit	12.51	ENSRNOT00000065917	Olr881 NCBI RGD Ensembl Show fit	olfactory receptor 881
chr19_+_15294248 Show fit	12.47	ENSRNOT00000024622	Ces1f NCBI RGD Ensembl Show fit	carboxylesterase 1F
chr8_+_52729003 Show fit	12.42	ENSRNOT00000081738	Nxpe4 NCBI RGD Ensembl Show fit	neurexophilin and PC-esterase domain family, member 4
chr4_-_176231344 Show fit	12.33	ENSRNOT00000049154	Slco1a1 NCBI RGD Ensembl Show fit	solute carrier organic anion transporter family, member 1a1
chr14_-_1785698 Show fit	12.29	ENSRNOT00000071182	Vom2r73 NCBI RGD Ensembl Show fit	vomeronasal 2 receptor, 73
chr6_+_128046780 Show fit	12.19	ENSRNOT00000078064	LOC500712 NCBI RGD Ensembl Show fit	Ab1-233
chrX_+_51286737 Show fit	12.16	ENSRNOT00000035692	Dmd NCBI RGD Ensembl Show fit	dystrophin
chr6_-_23316962 Show fit	12.13	ENSRNOT00000065421	Clip4 NCBI RGD Ensembl Show fit	CAP-GLY domain containing linker protein family, member 4
chr11_+_7210209 Show fit	11.94	ENSRNOT00000076695	Gbe1 NCBI RGD Ensembl Show fit	1,4-alpha-glucan branching enzyme 1
chr14_-_773281 Show fit	11.87	ENSRNOT00000045104 ENSRNOT00000050676 ENSRNOT00000049917	Vom2r-ps125 NCBI RGD Ensembl Show fit	vomeronasal 2 receptor, pseudogene 125
chr2_-_19808937 Show fit	11.86	ENSRNOT00000044237	Atp6ap1l NCBI RGD Ensembl Show fit	ATPase H+ transporting accessory protein 1 like
chr4_-_176026133 Show fit	11.82	ENSRNOT00000043374 ENSRNOT00000046598	Slco1a4 NCBI RGD Ensembl Show fit	solute carrier organic anion transporter family, member 1a4
chr2_+_243502073 Show fit	11.80	ENSRNOT00000015870	Adh7 NCBI RGD Ensembl Show fit	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr8_-_42430928 Show fit	11.80	ENSRNOT00000072172	Olr1257 NCBI RGD Ensembl Show fit	olfactory receptor 1257
chr14_+_812382 Show fit	11.77	ENSRNOT00000041506 ENSRNOT00000039993	AABR07014089.1 NCBI RGD Ensembl Show fit
chr8_-_38154344 Show fit	11.72	ENSRNOT00000068043	LOC100360095 NCBI RGD Ensembl Show fit	urinary protein 1-like
chr5_-_22769907 Show fit	11.72	ENSRNOT00000047805 ENSRNOT00000076167 ENSRNOT00000076507 ENSRNOT00000076113 ENSRNOT00000083779	Asph NCBI RGD Ensembl Show fit	aspartate-beta-hydroxylase
chr16_-_75518336 Show fit	11.72	ENSRNOT00000058037	Defa11 NCBI RGD Ensembl Show fit	defensin alpha 11
chr16_+_50181316 Show fit	11.70	ENSRNOT00000077662	F11 NCBI RGD Ensembl Show fit	coagulation factor XI
chr7_+_11769400 Show fit	11.63	ENSRNOT00000044417	Jsrp1 NCBI RGD Ensembl Show fit	junctional sarcoplasmic reticulum protein 1
chr4_+_14212925 Show fit	11.54	ENSRNOT00000076946	LOC103690020 NCBI RGD Ensembl Show fit	platelet glycoprotein 4-like
chr3_-_127500709 Show fit	11.53	ENSRNOT00000006330	Hao1 NCBI RGD Ensembl Show fit	hydroxyacid oxidase 1
chrX_-_104337203 Show fit	11.52	ENSRNOT00000050903	AABR07040565.1 NCBI RGD Ensembl Show fit
chr4_+_122244711 Show fit	11.44	ENSRNOT00000038251	Uroc1 NCBI RGD Ensembl Show fit	urocanate hydratase 1
chr9_+_8054466 Show fit	11.40	ENSRNOT00000081513	Adgre4 NCBI RGD Ensembl Show fit	adhesion G protein-coupled receptor E4
chr3_-_52447622 Show fit	11.37	ENSRNOT00000083552	Scn1a NCBI RGD Ensembl Show fit	sodium voltage-gated channel alpha subunit 1
chr7_+_139685573 Show fit	11.31	ENSRNOT00000088376	Pfkm NCBI RGD Ensembl Show fit	phosphofructokinase, muscle
chr13_-_52834134 Show fit	11.31	ENSRNOT00000038874	Igfn1 NCBI RGD Ensembl Show fit	immunoglobulin-like and fibronectin type III domain containing 1
chr4_+_166076156 Show fit	11.26	ENSRNOT00000007124	Prp2 NCBI RGD Ensembl Show fit	proline rich protein 2
chr17_+_15966234 Show fit	11.16	ENSRNOT00000084304	Wnk2 NCBI RGD Ensembl Show fit	WNK lysine deficient protein kinase 2
chr2_-_243407608 Show fit	11.09	ENSRNOT00000014631	Mttp NCBI RGD Ensembl Show fit	microsomal triglyceride transfer protein
chr10_-_46206135 Show fit	11.08	ENSRNOT00000091471	Cops3 NCBI RGD Ensembl Show fit	COP9 signalosome subunit 3
chr4_+_103495993 Show fit	11.07	ENSRNOT00000072325	AABR07061068.1 NCBI RGD Ensembl Show fit
chr18_-_64061472 Show fit	11.01	ENSRNOT00000022519	Fam210a NCBI RGD Ensembl Show fit	family with sequence similarity 210, member A
chr3_-_74790822 Show fit	11.00	ENSRNOT00000045888	LOC100912505 NCBI RGD Ensembl Show fit	olfactory receptor 8K3-like
chr8_+_87211819 Show fit	11.00	ENSRNOT00000086093	LOC100363289 NCBI RGD Ensembl Show fit	LRRGT00022-like
chr3_+_75936795 Show fit	10.91	ENSRNOT00000007603	Olr588 NCBI RGD Ensembl Show fit	olfactory receptor 588
chr1_+_229722768 Show fit	10.86	ENSRNOT00000017126	Olr339 NCBI RGD Ensembl Show fit	olfactory receptor 339
chr9_+_94286550 Show fit	10.82	ENSRNOT00000026504	Chrnd NCBI RGD Ensembl Show fit	cholinergic receptor nicotinic delta subunit
chr11_+_42259761 Show fit	10.77	ENSRNOT00000047310	Epha6 NCBI RGD Ensembl Show fit	Eph receptor A6
chr9_-_17693200 Show fit	10.68	ENSRNOT00000026716	Mrpl14 NCBI RGD Ensembl Show fit	mitochondrial ribosomal protein L14
chrX_+_15669191 Show fit	10.64	ENSRNOT00000013553	Magix NCBI RGD Ensembl Show fit	MAGI family member, X-linked
chr3_+_69549673 Show fit	10.53	ENSRNOT00000043974	Zfp804a NCBI RGD Ensembl Show fit	zinc finger protein 804A
chr9_-_50762082 Show fit	10.47	ENSRNOT00000015492	Mettl21c NCBI RGD Ensembl Show fit	methyltransferase like 21C
chr1_+_229889771 Show fit	10.43	ENSRNOT00000085941	Olr348 NCBI RGD Ensembl Show fit	olfactory receptor 348
chr1_+_94718402 Show fit	10.40	ENSRNOT00000046035	Uqcrb NCBI RGD Ensembl Show fit	ubiquinol-cytochrome c reductase binding protein
chrX_-_56765893 Show fit	10.40	ENSRNOT00000076283	Il1rapl1 NCBI RGD Ensembl Show fit	interleukin 1 receptor accessory protein-like 1
chr8_-_38549268 Show fit	10.39	ENSRNOT00000088001	LOC100912026 NCBI RGD Ensembl Show fit	urinary protein 3-like
chr19_-_22194740 Show fit	10.36	ENSRNOT00000086187	Phkb NCBI RGD Ensembl Show fit	phosphorylase kinase regulatory subunit beta
chr1_+_116869957 Show fit	10.35	ENSRNOT00000075203	Vom2r25 NCBI RGD Ensembl Show fit	vomeronasal 2 receptor, 25
chr11_-_43617633 Show fit	10.30	ENSRNOT00000060874	Olr1557 NCBI RGD Ensembl Show fit	olfactory receptor 1557
chr3_+_112228919 Show fit	10.23	ENSRNOT00000011761	Capn3 NCBI RGD Ensembl Show fit	calpain 3
chr6_-_127656603 Show fit	10.22	ENSRNOT00000015516	Serpina11 NCBI RGD Ensembl Show fit	serpin family A member 11
chr2_+_22910236 Show fit	10.15	ENSRNOT00000078266	Homer1 NCBI RGD Ensembl Show fit	homer scaffolding protein 1
chrX_+_145558840 Show fit	10.14	ENSRNOT00000032522	4931400O07Rik NCBI RGD Ensembl Show fit	RIKEN cDNA 4931400O07 gene
chr1_-_49844547 Show fit	10.14	ENSRNOT00000086127 ENSRNOT00000077423 ENSRNOT00000089439 ENSRNOT00000090521	AABR07001519.1 NCBI RGD Ensembl Show fit
chr3_+_112228720 Show fit	10.12	ENSRNOT00000079079	Capn3 NCBI RGD Ensembl Show fit	calpain 3
chr3_+_11653529 Show fit	10.11	ENSRNOT00000091048	Ak1 NCBI RGD Ensembl Show fit	adenylate kinase 1
chr11_+_20474483 Show fit	10.10	ENSRNOT00000082417 ENSRNOT00000002895	Ncam2 NCBI RGD Ensembl Show fit	neural cell adhesion molecule 2
chr16_-_40025401 Show fit	10.05	ENSRNOT00000066639	Asb5 NCBI RGD Ensembl Show fit	ankyrin repeat and SOCS box-containing 5
chr4_+_101639641 Show fit	10.03	ENSRNOT00000058282	AABR07060952.1 NCBI RGD Ensembl Show fit
chr3_-_78016906 Show fit	10.01	ENSRNOT00000089048	Olr687 NCBI RGD Ensembl Show fit	olfactory receptor 687
chrX_-_64726210 Show fit	9.99	ENSRNOT00000076012 ENSRNOT00000086265	Asb12 NCBI RGD Ensembl Show fit	ankyrin repeat and SOCS box-containing 12
chr11_-_81444375 Show fit	9.87	ENSRNOT00000058479 ENSRNOT00000078131 ENSRNOT00000080949 ENSRNOT00000080562 ENSRNOT00000084867	Kng1 NCBI RGD Ensembl Show fit	kininogen 1
chr7_-_70552897 Show fit	9.87	ENSRNOT00000080594	Kif5a NCBI RGD Ensembl Show fit	kinesin family member 5A
chr5_-_77433847 Show fit	9.86	ENSRNOT00000076906 ENSRNOT00000043056	LOC500473 NCBI RGD Ensembl Show fit Mup4 NCBI RGD Ensembl Show fit	similar to alpha-2u globulin PGCL2 major urinary protein 4
chrX_-_123867149 Show fit	9.83	ENSRNOT00000089754	Rhox3 NCBI RGD Ensembl Show fit	reproductive homeobox on X chromosome 3
chr1_-_173456488 Show fit	9.83	ENSRNOT00000044753	Olr282 NCBI RGD Ensembl Show fit	olfactory receptor 282
chrX_-_65400298 Show fit	9.79	ENSRNOT00000032121	Vsig4 NCBI RGD Ensembl Show fit	V-set and immunoglobulin domain containing 4
chr20_-_1109027 Show fit	9.78	ENSRNOT00000051315	Olr1696 NCBI RGD Ensembl Show fit	olfactory receptor 1696
chr5_+_132005738 Show fit	9.77	ENSRNOT00000041421	Skint4 NCBI RGD Ensembl Show fit	selection and upkeep of intraepithelial T cells 4
chr4_+_146276862 Show fit	9.69	ENSRNOT00000009705	Slc6a1 NCBI RGD Ensembl Show fit	solute carrier family 6 member 1
chr1_-_67853552 Show fit	9.68	ENSRNOT00000080755 ENSRNOT00000003545	Vom2r32 NCBI RGD Ensembl Show fit	vomeronasal 2 receptor, 32
chr16_+_74292438 Show fit	9.65	ENSRNOT00000026197	Vdac3 NCBI RGD Ensembl Show fit	voltage-dependent anion channel 3
chr4_+_175814118 Show fit	9.64	ENSRNOT00000013409 ENSRNOT00000013514	Slco1b2 NCBI RGD Ensembl Show fit	solute carrier organic anion transporter family, member 1B2

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou1f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.5	31.4	GO:1990868	response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
9.2	248.0	GO:0019373	epoxygenase P450 pathway(GO:0019373)
7.3	58.3	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
7.1	28.3	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
6.8	20.3	GO:1990091	sodium-dependent self proteolysis(GO:1990091)
5.2	15.7	GO:0014916	regulation of lung blood pressure(GO:0014916)
5.0	15.1	GO:0006526	arginine biosynthetic process(GO:0006526)
4.6	13.8	GO:0010034	response to acetate(GO:0010034)
4.5	31.3	GO:0051694	pointed-end actin filament capping(GO:0051694)
4.3	17.2	GO:0002325	natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
4.3	21.4	GO:0098953	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
4.3	68.1	GO:0031034	myosin filament assembly(GO:0031034)
4.1	16.3	GO:0002933	lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
4.1	12.2	GO:0016203	muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
4.0	19.9	GO:0071400	cellular response to oleic acid(GO:0071400)
3.8	18.9	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
3.6	25.0	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
3.5	14.1	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
3.4	37.7	GO:0070327	thyroid hormone transport(GO:0070327)
3.4	10.1	GO:0046103	inosine biosynthetic process(GO:0046103)
3.3	13.4	GO:0002074	extraocular skeletal muscle development(GO:0002074)
3.3	9.9	GO:0098971	anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
3.3	13.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
3.1	3.1	GO:1904959	regulation of cytochrome-c oxidase activity(GO:1904959)
3.1	45.8	GO:0034310	primary alcohol catabolic process(GO:0034310)
3.1	9.2	GO:0045959	negative regulation of complement activation, classical pathway(GO:0045959)
2.9	46.0	GO:0035634	response to stilbenoid(GO:0035634)
2.9	11.4	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
2.8	11.3	GO:0061622	glycolytic process through glucose-1-phosphate(GO:0061622)
2.7	16.5	GO:0050917	sensory perception of umami taste(GO:0050917)
2.7	8.1	GO:0021539	subthalamus development(GO:0021539)
2.7	10.7	GO:0001692	histamine metabolic process(GO:0001692)
2.7	8.0	GO:0099552	trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
2.5	15.2	GO:0006572	tyrosine catabolic process(GO:0006572)
2.4	33.7	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
2.4	7.1	GO:0033306	phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
2.3	11.7	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
2.3	7.0	GO:0045819	cellular response to water deprivation(GO:0042631) positive regulation of glycogen catabolic process(GO:0045819)
2.3	6.9	GO:0019255	UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
2.3	9.2	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.2	20.1	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
2.2	6.7	GO:0009249	protein lipoylation(GO:0009249)
2.2	15.4	GO:0035610	protein side chain deglutamylation(GO:0035610)
2.2	4.3	GO:0031583	phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
2.2	8.6	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
2.1	8.6	GO:1903413	negative regulation of iron ion transmembrane transport(GO:0034760) cellular response to bile acid(GO:1903413)
2.1	6.4	GO:0043490	malate-aspartate shuttle(GO:0043490)
2.1	14.8	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
2.1	2.1	GO:2000157	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
2.1	6.2	GO:0042369	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369) response to sodium phosphate(GO:1904383)
2.0	6.1	GO:0043605	cellular amide catabolic process(GO:0043605)
2.0	12.1	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
2.0	26.1	GO:0052695	cellular glucuronidation(GO:0052695)
2.0	6.0	GO:0006045	N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
2.0	17.6	GO:0061303	cornea development in camera-type eye(GO:0061303)
1.9	5.8	GO:0070946	neutrophil mediated killing of gram-positive bacterium(GO:0070946)
1.9	9.7	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.9	5.8	GO:0006552	leucine catabolic process(GO:0006552)
1.9	20.9	GO:0048739	cardiac muscle fiber development(GO:0048739)
1.9	49.2	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
1.8	27.4	GO:0015671	oxygen transport(GO:0015671)
1.8	5.4	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359) negative regulation of binding of sperm to zona pellucida(GO:2000360)
1.8	5.3	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
1.7	2190.6	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
1.7	3.4	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
1.7	8.3	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
1.7	5.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
1.7	26.6	GO:0019236	response to pheromone(GO:0019236)
1.7	1.7	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
1.6	6.6	GO:0009992	cellular water homeostasis(GO:0009992)
1.6	4.9	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
1.6	6.5	GO:0019474	lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
1.6	6.4	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.6	8.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.6	9.5	GO:1903352	L-ornithine transmembrane transport(GO:1903352)
1.5	3.1	GO:0006579	amino-acid betaine catabolic process(GO:0006579)
1.5	6.1	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.5	9.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
1.5	7.5	GO:0001574	ganglioside biosynthetic process(GO:0001574)
1.5	6.0	GO:0002434	immune complex clearance(GO:0002434)
1.5	11.8	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
1.4	4.3	GO:0034769	basement membrane disassembly(GO:0034769)
1.4	10.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.4	5.8	GO:0002877	regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
1.4	5.8	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
1.4	5.8	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
1.4	8.4	GO:0045329	carnitine biosynthetic process(GO:0045329)
1.4	5.6	GO:1903576	response to L-arginine(GO:1903576)
1.4	18.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
1.4	5.4	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
1.4	6.8	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
1.3	4.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
1.3	4.0	GO:0046687	response to chromate(GO:0046687)
1.3	12.0	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
1.3	21.3	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
1.3	9.2	GO:0015669	gas transport(GO:0015669)
1.3	10.4	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
1.3	3.8	GO:0033058	directional locomotion(GO:0033058)
1.2	2.5	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.2	6.1	GO:0060327	cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
1.2	4.9	GO:0045423	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
1.2	27.9	GO:0015721	bile acid and bile salt transport(GO:0015721)
1.2	8.5	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
1.2	2.4	GO:0002314	germinal center B cell differentiation(GO:0002314)
1.1	3.4	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
1.1	13.6	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
1.1	12.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
1.1	3.4	GO:0010133	proline catabolic process to glutamate(GO:0010133)
1.1	6.7	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
1.1	3.3	GO:0070175	positive regulation of enamel mineralization(GO:0070175)
1.1	2.2	GO:0014016	neuroblast differentiation(GO:0014016)
1.1	4.4	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.0	5.2	GO:0021780	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.0	3.1	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
1.0	10.3	GO:0097105	presynaptic membrane assembly(GO:0097105)
1.0	18.5	GO:1900004	negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
1.0	1.0	GO:0032672	regulation of interleukin-3 production(GO:0032672)
1.0	2.9	GO:0051867	general adaptation syndrome, behavioral process(GO:0051867)
1.0	2.9	GO:0031632	positive regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031632)
0.9	5.7	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.9	13.2	GO:0015693	magnesium ion transport(GO:0015693)
0.9	2.8	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.9	3.7	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.9	2.7	GO:0009644	response to high light intensity(GO:0009644)
0.9	2.7	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.9	2.6	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.9	5.2	GO:0010266	response to vitamin B1(GO:0010266) response to platinum ion(GO:0070541)
0.9	3.4	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.9	5.1	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.8	16.1	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.8	2.5	GO:0033869	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.8	2.4	GO:0006529	asparagine biosynthetic process(GO:0006529)
0.8	8.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.8	8.0	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.8	8.0	GO:0071373	cellular response to luteinizing hormone stimulus(GO:0071373)
0.8	2.4	GO:0044726	protection of DNA demethylation of female pronucleus(GO:0044726)
0.8	6.3	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.8	8.5	GO:0000338	protein deneddylation(GO:0000338)
0.8	3.9	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
0.8	13.1	GO:0009750	response to fructose(GO:0009750)
0.8	3.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.8	5.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.8	3.0	GO:0046338	phosphatidylethanolamine catabolic process(GO:0046338)
0.8	8.3	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.7	40.3	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.7	2.2	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.7	9.6	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.7	5.9	GO:0030449	regulation of complement activation(GO:0030449)
0.7	5.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.7	2.2	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.7	3.7	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.7	11.5	GO:0044364	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.7	0.7	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.7	8.5	GO:0042407	cristae formation(GO:0042407)
0.7	2.8	GO:0002188	translation reinitiation(GO:0002188)
0.7	8.9	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.7	10.8	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.7	3.4	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.7	11.4	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.7	6.0	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.7	4.0	GO:0070842	aggresome assembly(GO:0070842)
0.6	13.8	GO:0030574	collagen catabolic process(GO:0030574)
0.6	1.9	GO:0021589	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.6	32.3	GO:0042773	ATP synthesis coupled electron transport(GO:0042773)
0.6	3.0	GO:0034552	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.6	6.0	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.6	1.8	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.6	17.2	GO:0050892	intestinal absorption(GO:0050892)
0.6	1.8	GO:0060764	cell-cell signaling involved in mammary gland development(GO:0060764) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.6	2.9	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.6	9.8	GO:2000637	positive regulation of gene silencing by miRNA(GO:2000637)
0.6	2.8	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.5	4.9	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.5	3.8	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.5	136.9	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.5	10.3	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.5	2.7	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.5	2.7	GO:0097688	glutamate receptor clustering(GO:0097688)
0.5	4.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.5	2.7	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.5	2.7	GO:0008292	acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.5	9.4	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.5	2.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.5	3.6	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.5	4.6	GO:0060539	diaphragm development(GO:0060539)
0.5	4.6	GO:0009235	cobalamin metabolic process(GO:0009235)
0.5	8.5	GO:0010818	T cell chemotaxis(GO:0010818)
0.5	1.5	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
0.5	3.5	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.5	4.7	GO:0045072	regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.5	0.5	GO:0071314	cellular response to cocaine(GO:0071314)
0.5	10.6	GO:0045109	intermediate filament organization(GO:0045109)
0.5	1.4	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.5	7.7	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.5	4.1	GO:0015866	ADP transport(GO:0015866)
0.4	6.6	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4	4.4	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.4	11.6	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4	4.7	GO:0022904	respiratory electron transport chain(GO:0022904)
0.4	21.2	GO:0050909	sensory perception of taste(GO:0050909)
0.4	4.5	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.4	0.4	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.4	18.8	GO:0021762	substantia nigra development(GO:0021762)
0.4	1.6	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.4	1.6	GO:0060023	soft palate development(GO:0060023)
0.4	1.6	GO:0097332	response to antipsychotic drug(GO:0097332)
0.4	1.6	GO:1900170	negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.4	2.3	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4	4.3	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.4	1.9	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.4	0.8	GO:1903719	regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.4	5.7	GO:0035641	locomotory exploration behavior(GO:0035641)
0.4	1.1	GO:1901367	response to L-cysteine(GO:1901367)
0.4	1.9	GO:0009624	response to nematode(GO:0009624)
0.4	5.9	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.4	2.2	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.4	5.2	GO:0036315	cellular response to sterol(GO:0036315)
0.4	3.7	GO:1990834	regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) response to odorant(GO:1990834)
0.4	0.7	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.4	1.8	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.4	1.1	GO:1901094	regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.4	2.5	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.4	2.5	GO:0070054	mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.4	0.7	GO:0044268	multicellular organismal protein metabolic process(GO:0044268)
0.4	1.4	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.4	1.4	GO:0046222	mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.4	10.6	GO:0006073	glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.3	1.7	GO:0006311	meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.3	6.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.3	1.4	GO:0010157	response to chlorate(GO:0010157)
0.3	1.7	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.3	0.7	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.3	2.0	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.3	25.2	GO:0008203	cholesterol metabolic process(GO:0008203)
0.3	2.3	GO:0003360	brainstem development(GO:0003360)
0.3	3.2	GO:0019321	pentose metabolic process(GO:0019321)
0.3	5.1	GO:0043248	proteasome assembly(GO:0043248)
0.3	1.3	GO:0098963	dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.3	3.8	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.3	1.6	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.3	10.9	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3	7.8	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
0.3	5.5	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.3	3.6	GO:0042448	progesterone metabolic process(GO:0042448)
0.3	0.3	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.3	3.9	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.3	1.8	GO:0045792	negative regulation of cell size(GO:0045792)
0.3	3.8	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.3	1.4	GO:0089700	protein kinase D signaling(GO:0089700)
0.3	1.4	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.3	5.1	GO:0007602	phototransduction(GO:0007602)
0.3	3.3	GO:0042711	maternal behavior(GO:0042711)
0.3	1.7	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3	1.7	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.3	4.4	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3	1.4	GO:0060721	regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.3	3.2	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.3	1.9	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.3	1.1	GO:0072709	cellular response to sorbitol(GO:0072709)
0.3	2.4	GO:0015886	heme transport(GO:0015886)
0.3	1.8	GO:0010579	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.3	4.5	GO:0097503	sialylation(GO:0097503)
0.3	3.1	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.3	1.3	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.3	1.3	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.3	1.8	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.3	2.5	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.2	2.4	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.2	4.3	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.2	1.9	GO:0070417	cellular response to cold(GO:0070417)
0.2	1.8	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2	0.9	GO:0001579	medium-chain fatty acid transport(GO:0001579)
0.2	1.1	GO:0019563	glycerol catabolic process(GO:0019563)
0.2	2.0	GO:0030259	lipid glycosylation(GO:0030259)
0.2	2.9	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2	1.3	GO:0032790	ribosome disassembly(GO:0032790)
0.2	1.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2	3.8	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.2	2.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.2	0.4	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2	2.7	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.2	12.5	GO:0045454	cell redox homeostasis(GO:0045454)
0.2	1.2	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.2	0.8	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.2	0.6	GO:2000224	regulation of testosterone biosynthetic process(GO:2000224)
0.2	7.8	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.2	2.2	GO:0042730	fibrinolysis(GO:0042730)
0.2	2.2	GO:0001887	selenium compound metabolic process(GO:0001887)
0.2	1.1	GO:0015705	iodide transport(GO:0015705)
0.2	1.1	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.2	2.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.2	0.8	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2	2.2	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.2	4.0	GO:0045103	intermediate filament-based process(GO:0045103)
0.2	2.7	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.2	1.6	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.2	1.4	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.2	0.7	GO:0036371	T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2	1.4	GO:0061050	regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.2	1.1	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2	1.9	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.2	1.0	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.2	1.2	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2	2.0	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.2	2.5	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2	2.6	GO:0033194	response to hydroperoxide(GO:0033194)
0.2	3.6	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.2	2.9	GO:0035404	histone-serine phosphorylation(GO:0035404)
0.2	7.0	GO:0051339	regulation of lyase activity(GO:0051339)
0.2	0.3	GO:0071348	cellular response to interleukin-11(GO:0071348)
0.2	1.7	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	8.7	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.2	2.8	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.2	3.0	GO:0048240	sperm capacitation(GO:0048240)
0.2	0.8	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.2	4.6	GO:0007413	axonal fasciculation(GO:0007413)
0.2	0.8	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.2	1.5	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2	1.2	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.6	GO:0033700	phospholipid efflux(GO:0033700)
0.1	3.6	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.1	5.7	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.3	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	1.3	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.1	4.0	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	1.1	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.1	1.8	GO:0042755	eating behavior(GO:0042755)
0.1	0.4	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1	2.3	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.1	1.0	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.8	GO:0032262	pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
0.1	0.4	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.1	0.7	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	1.4	GO:0007512	adult heart development(GO:0007512)
0.1	2.7	GO:0045116	protein neddylation(GO:0045116)
0.1	1.6	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.1	0.8	GO:0050957	equilibrioception(GO:0050957)
0.1	2.8	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	0.3	GO:0097327	response to antineoplastic agent(GO:0097327)
0.1	0.3	GO:1903999	regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999)
0.1	4.6	GO:0030239	myofibril assembly(GO:0030239)
0.1	1.4	GO:2000269	regulation of fibroblast apoptotic process(GO:2000269)
0.1	0.4	GO:0060613	fat pad development(GO:0060613)
0.1	4.1	GO:0032543	mitochondrial translation(GO:0032543)
0.1	5.4	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1	1.3	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1	2.8	GO:0006730	one-carbon metabolic process(GO:0006730)
0.1	0.7	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.1	7.1	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.1	0.5	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.1	1.2	GO:1901663	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.8	GO:0019430	removal of superoxide radicals(GO:0019430)
0.1	2.2	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.1	0.5	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.1	0.3	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1	1.7	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.1	1.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.9	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1	2.0	GO:0009303	rRNA transcription(GO:0009303)
0.1	1.4	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.1	1.6	GO:0021516	dorsal spinal cord development(GO:0021516)
0.1	0.4	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.1	0.9	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.1	0.6	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.1	0.7	GO:0061088	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1	0.2	GO:0007343	egg activation(GO:0007343)
0.1	0.8	GO:0015677	copper ion import(GO:0015677)
0.1	1.6	GO:0042092	type 2 immune response(GO:0042092)
0.1	2.0	GO:0043039	tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039)
0.1	0.3	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.1	1.4	GO:0060479	lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.0	0.5	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.2	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.3	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.6	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.5	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	2.8	GO:0036503	ERAD pathway(GO:0036503)
0.0	0.2	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.1	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.0	0.3	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.2	GO:0009642	response to light intensity(GO:0009642)
0.0	1.3	GO:0035094	response to nicotine(GO:0035094)
0.0	0.9	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.3	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	1.0	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.0	0.8	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	1.0	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.4	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.8	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
0.0	2.5	GO:0007606	sensory perception of chemical stimulus(GO:0007606)
0.0	0.1	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.4	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.1	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0	0.1	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.0	0.2	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.2	GO:0007339	binding of sperm to zona pellucida(GO:0007339)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.1	54.7	GO:0005826	actomyosin contractile ring(GO:0005826)
4.9	19.6	GO:0099524	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
3.8	11.3	GO:0005945	6-phosphofructokinase complex(GO:0005945)
3.1	9.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
2.9	29.5	GO:0045179	apical cortex(GO:0045179)
2.9	14.4	GO:0043159	acrosomal matrix(GO:0043159)
2.6	29.0	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750)
2.5	27.4	GO:0005833	hemoglobin complex(GO:0005833)
2.3	68.0	GO:0034364	high-density lipoprotein particle(GO:0034364)
2.3	9.2	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
2.2	11.1	GO:0031528	microvillus membrane(GO:0031528)
2.0	8.0	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
1.5	6.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
1.4	4.2	GO:0061673	mitotic spindle astral microtubule(GO:0061673)
1.3	19.8	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
1.3	147.3	GO:0072562	blood microparticle(GO:0072562)
1.3	3.8	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
1.2	63.2	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.2	8.4	GO:0061617	MICOS complex(GO:0061617)
1.2	6.0	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.2	14.0	GO:0005859	muscle myosin complex(GO:0005859)
1.1	8.0	GO:0043194	axon initial segment(GO:0043194)
1.1	35.6	GO:0042588	zymogen granule(GO:0042588)
1.1	11.7	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
1.1	14.7	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
1.0	3.1	GO:0031372	UBC13-MMS2 complex(GO:0031372)
1.0	3.1	GO:0034774	secretory granule lumen(GO:0034774)
1.0	9.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.9	4.6	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.9	11.9	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.9	2.7	GO:0098982	glycine-gated chloride channel complex(GO:0016935) GABA-ergic synapse(GO:0098982)
0.9	39.4	GO:0043034	costamere(GO:0043034)
0.9	5.3	GO:0002142	stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.8	6.8	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.8	9.8	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.8	0.8	GO:0045275	respiratory chain complex III(GO:0045275)
0.8	4.5	GO:0097441	basilar dendrite(GO:0097441)
0.7	82.8	GO:0030018	Z disc(GO:0030018)
0.7	3.7	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.7	28.3	GO:0031672	A band(GO:0031672)
0.7	2.8	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.7	19.7	GO:0070469	respiratory chain(GO:0070469)
0.7	13.3	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.7	7.3	GO:0072546	ER membrane protein complex(GO:0072546)
0.6	3.1	GO:0035061	interchromatin granule(GO:0035061)
0.6	3.1	GO:0072534	perineuronal net(GO:0072534)
0.6	1.2	GO:0005955	calcineurin complex(GO:0005955)
0.6	4.6	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.6	1.7	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.6	2.9	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.6	4.6	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6	13.0	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.6	1.1	GO:0070069	cytochrome complex(GO:0070069)
0.6	1.7	GO:0070939	Dsl1p complex(GO:0070939)
0.5	10.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.5	1.6	GO:0005592	collagen type XI trimer(GO:0005592)
0.5	8.8	GO:0022624	proteasome accessory complex(GO:0022624)
0.5	2.5	GO:0002081	outer acrosomal membrane(GO:0002081)
0.5	1.5	GO:0000802	transverse filament(GO:0000802)
0.5	3.0	GO:0005663	DNA replication factor C complex(GO:0005663)
0.5	12.8	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.5	1.9	GO:0070552	BRISC complex(GO:0070552)
0.5	2.8	GO:0032280	symmetric synapse(GO:0032280)
0.5	8.6	GO:0001520	outer dense fiber(GO:0001520)
0.5	3.6	GO:0035686	sperm fibrous sheath(GO:0035686)
0.4	3.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4	11.6	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.4	4.4	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.4	25.7	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4	22.0	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.4	8.0	GO:0060170	ciliary membrane(GO:0060170)
0.4	6.9	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.4	3.9	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.4	1.5	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.4	3.4	GO:0043196	varicosity(GO:0043196)
0.4	61.4	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.4	1.1	GO:1990415	Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.4	2.5	GO:0005640	nuclear outer membrane(GO:0005640)
0.4	44.6	GO:0001669	acrosomal vesicle(GO:0001669)
0.3	8.0	GO:0097440	apical dendrite(GO:0097440)
0.3	2.8	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.3	1.4	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.3	2.1	GO:0051286	cell tip(GO:0051286)
0.3	13.7	GO:0009925	basal plasma membrane(GO:0009925)
0.3	5.7	GO:0097449	astrocyte projection(GO:0097449)
0.3	2.2	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.3	2.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3	1.6	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.3	7.8	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.3	2.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.3	0.9	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3	2.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.3	5.3	GO:0033270	paranode region of axon(GO:0033270)
0.3	5.0	GO:0033391	chromatoid body(GO:0033391)
0.3	1925.0	GO:0016021	integral component of membrane(GO:0016021)
0.3	0.9	GO:0097433	dense body(GO:0097433)
0.3	1.7	GO:0005921	gap junction(GO:0005921)
0.3	0.8	GO:0045098	type III intermediate filament(GO:0045098)
0.3	1.3	GO:0070695	FHF complex(GO:0070695)
0.3	2.0	GO:0005916	fascia adherens(GO:0005916)
0.2	12.5	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.2	0.2	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.2	3.5	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.2	26.2	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.2	249.3	GO:0005615	extracellular space(GO:0005615)
0.2	0.9	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.2	8.6	GO:0030017	sarcomere(GO:0030017)
0.2	1.8	GO:0005869	dynactin complex(GO:0005869)
0.2	2.0	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2	5.7	GO:0008180	COP9 signalosome(GO:0008180)
0.2	0.4	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.2	1.4	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.2	0.4	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.2	4.9	GO:0005801	cis-Golgi network(GO:0005801)
0.2	3.6	GO:0001673	male germ cell nucleus(GO:0001673)
0.2	2.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.2	2.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.2	1.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.2	2.0	GO:0000801	central element(GO:0000801)
0.2	1.9	GO:0001772	immunological synapse(GO:0001772)
0.2	5.0	GO:0042734	presynaptic membrane(GO:0042734)
0.2	1.7	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	1.7	GO:0005675	holo TFIIH complex(GO:0005675)
0.1	0.8	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.1	0.9	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.7	GO:0070847	core mediator complex(GO:0070847)
0.1	9.4	GO:0031966	mitochondrial membrane(GO:0031966)
0.1	4.1	GO:0016235	aggresome(GO:0016235)
0.1	1.7	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	2.1	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	0.8	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	0.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.4	GO:0098827	endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1	3.4	GO:0045171	intercellular bridge(GO:0045171)
0.1	0.3	GO:1990745	EARP complex(GO:1990745)
0.1	2.0	GO:0043235	receptor complex(GO:0043235)
0.1	0.8	GO:0071564	npBAF complex(GO:0071564)
0.1	0.9	GO:0032156	septin cytoskeleton(GO:0032156)
0.1	0.8	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.5	GO:0000974	Prp19 complex(GO:0000974)
0.1	1.0	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	2.7	GO:0005871	kinesin complex(GO:0005871)
0.0	0.2	GO:0070545	PeBoW complex(GO:0070545)
0.0	1.7	GO:0000502	proteasome complex(GO:0000502)
0.0	2.7	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	33.9	GO:0005739	mitochondrion(GO:0005739)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	2.8	GO:0009986	cell surface(GO:0009986)
0.0	0.9	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.2	GO:0005902	microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
19.4	58.3	GO:0004556	alpha-amylase activity(GO:0004556)
17.0	85.2	GO:0005550	pheromone binding(GO:0005550)
14.5	43.6	GO:0003844	1,4-alpha-glucan branching enzyme activity(GO:0003844)
9.3	28.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
8.2	247.3	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
6.4	199.5	GO:0015020	glucuronosyltransferase activity(GO:0015020)
5.3	21.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
5.1	15.4	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
5.1	15.2	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
4.6	23.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
4.4	13.1	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
4.3	17.2	GO:0016019	peptidoglycan receptor activity(GO:0016019)
4.0	15.8	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
3.8	19.2	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
3.8	19.2	GO:0051373	FATZ binding(GO:0051373)
3.8	22.8	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
3.7	29.8	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
3.4	13.6	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
3.4	10.1	GO:0031721	hemoglobin alpha binding(GO:0031721)
3.3	20.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
3.0	3.0	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
3.0	14.9	GO:0005534	galactose binding(GO:0005534)
3.0	17.8	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
2.9	41.3	GO:0033038	bitter taste receptor activity(GO:0033038)
2.8	16.7	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
2.4	17.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
2.4	19.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
2.4	11.8	GO:0004031	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
2.3	37.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
2.3	7.0	GO:0031893	vasopressin receptor binding(GO:0031893)
2.3	9.2	GO:0019002	GMP binding(GO:0019002)
2.2	15.7	GO:0019238	cyclohydrolase activity(GO:0019238)
2.2	6.7	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
2.2	6.7	GO:0031177	phosphopantetheine binding(GO:0031177)
2.2	8.9	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
2.2	13.1	GO:0015245	fatty acid transporter activity(GO:0015245)
2.2	8.6	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
2.1	6.4	GO:0009384	N-acylmannosamine kinase activity(GO:0009384)
2.1	6.2	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
2.1	831.2	GO:0005549	odorant binding(GO:0005549)
2.0	8.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
2.0	6.1	GO:0008281	sulfonylurea receptor activity(GO:0008281)
2.0	13.9	GO:0003996	acyl-CoA ligase activity(GO:0003996)
2.0	27.9	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
2.0	19.9	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
2.0	7.8	GO:0055100	adiponectin binding(GO:0055100)
1.8	11.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
1.8	5.4	GO:0030156	benzodiazepine receptor binding(GO:0030156)
1.7	5.2	GO:0004655	porphobilinogen synthase activity(GO:0004655)
1.7	5.1	GO:0031770	growth hormone-releasing hormone receptor binding(GO:0031770)
1.7	15.3	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
1.6	11.5	GO:0033592	RNA strand annealing activity(GO:0033592)
1.6	9.9	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
1.6	34.6	GO:0008395	steroid hydroxylase activity(GO:0008395)
1.6	19.6	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.6	4.9	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
1.6	8.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.6	42.9	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.6	18.6	GO:0070324	thyroid hormone binding(GO:0070324)
1.5	4.6	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
1.5	1350.8	GO:0004984	olfactory receptor activity(GO:0004984)
1.5	5.9	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
1.5	8.9	GO:0005148	prolactin receptor binding(GO:0005148)
1.5	1.5	GO:0032427	GBD domain binding(GO:0032427)
1.5	10.3	GO:0004064	arylesterase activity(GO:0004064)
1.5	5.8	GO:0032190	acrosin binding(GO:0032190)
1.4	17.4	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
1.4	17.4	GO:0005344	oxygen transporter activity(GO:0005344)
1.4	25.9	GO:0005523	tropomyosin binding(GO:0005523)
1.4	16.7	GO:0031432	titin binding(GO:0031432)
1.4	6.9	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
1.3	5.4	GO:0050682	AF-2 domain binding(GO:0050682)
1.3	8.0	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
1.3	1.3	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) alkane 1-monooxygenase activity(GO:0018685)
1.3	5.2	GO:0019166	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.3	6.4	GO:0019862	IgA binding(GO:0019862)
1.3	3.8	GO:0047522	15-oxoprostaglandin 13-oxidase activity(GO:0047522)
1.3	6.4	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
1.3	17.8	GO:0008179	adenylate cyclase binding(GO:0008179)
1.3	3.8	GO:0032810	sterol response element binding(GO:0032810)
1.3	2.5	GO:0004875	complement receptor activity(GO:0004875)
1.3	3.8	GO:0051538	succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
1.3	11.3	GO:0070061	fructose binding(GO:0070061)
1.2	6.2	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
1.2	3.7	GO:0004775	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
1.2	8.5	GO:0035375	zymogen binding(GO:0035375)
1.2	4.8	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
1.2	24.9	GO:0034185	apolipoprotein binding(GO:0034185)
1.2	5.9	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
1.2	130.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
1.2	5.8	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
1.1	20.4	GO:0001848	complement binding(GO:0001848)
1.1	5.7	GO:0097016	L27 domain binding(GO:0097016)
1.1	3.4	GO:0004657	proline dehydrogenase activity(GO:0004657)
1.1	4.5	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.1	13.4	GO:0004000	adenosine deaminase activity(GO:0004000)
1.1	3.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.0	12.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
1.0	2.9	GO:0000991	transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.9	10.4	GO:0019966	interleukin-1 binding(GO:0019966)
0.9	4.7	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.9	2.8	GO:0005502	11-cis retinal binding(GO:0005502)
0.9	4.7	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.9	2.7	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.9	2.7	GO:0022852	glycine-gated chloride ion channel activity(GO:0022852)
0.9	2.7	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.9	4.4	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.9	1.8	GO:0071936	coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.9	7.0	GO:0022842	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.9	3.5	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.9	6.1	GO:0019863	IgE binding(GO:0019863)
0.8	6.8	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.8	2.5	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.8	16.5	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.8	8.0	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.8	2.4	GO:0005427	proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322) oligopeptide transmembrane transporter activity(GO:0035673)
0.8	8.7	GO:0004017	adenylate kinase activity(GO:0004017)
0.8	7.6	GO:0003680	AT DNA binding(GO:0003680)
0.8	0.8	GO:0004985	opioid receptor activity(GO:0004985)
0.8	5.3	GO:0009881	photoreceptor activity(GO:0009881)
0.7	2.2	GO:0047708	biotinidase activity(GO:0047708)
0.7	2.2	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.7	2.9	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.7	10.8	GO:0042166	acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.7	2.9	GO:0000829	inositol heptakisphosphate kinase activity(GO:0000829)
0.7	2.9	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.7	5.7	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.7	2.8	GO:0042806	fucose binding(GO:0042806)
0.7	6.0	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.6	4.5	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.6	10.8	GO:0001594	trace-amine receptor activity(GO:0001594)
0.6	2.5	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.6	4.9	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.6	9.9	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.6	16.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.6	7.8	GO:0005243	gap junction channel activity(GO:0005243)
0.6	27.5	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.6	16.5	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.6	7.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.6	68.1	GO:0005179	hormone activity(GO:0005179)
0.6	11.0	GO:0017166	vinculin binding(GO:0017166)
0.6	4.0	GO:0061133	endopeptidase activator activity(GO:0061133)
0.6	4.6	GO:0008172	S-methyltransferase activity(GO:0008172)
0.6	2.2	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.6	6.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.6	5.0	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.5	3.8	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.5	6.0	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.5	3.3	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5	10.8	GO:0005003	ephrin receptor activity(GO:0005003)
0.5	2.7	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
0.5	2.7	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.5	10.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.5	3.7	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.5	5.2	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.5	5.7	GO:0019864	IgG binding(GO:0019864)
0.5	2.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.5	26.0	GO:0009055	electron carrier activity(GO:0009055)
0.5	3.6	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.5	7.6	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.5	2.0	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.5	3.4	GO:0045499	chemorepellent activity(GO:0045499)
0.5	5.4	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.5	2.9	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5	1.9	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.5	1.9	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.5	6.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.5	1.8	GO:0008940	nitrate reductase activity(GO:0008940)
0.5	1.8	GO:0048763	ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.5	4.1	GO:0005347	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.4	4.8	GO:0042301	phosphate ion binding(GO:0042301)
0.4	3.9	GO:0016531	copper chaperone activity(GO:0016531)
0.4	91.7	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.4	6.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.4	15.5	GO:0051879	Hsp90 protein binding(GO:0051879)
0.4	4.9	GO:0016805	dipeptidase activity(GO:0016805)
0.4	4.9	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.4	7.5	GO:0008373	sialyltransferase activity(GO:0008373)
0.4	7.8	GO:0004383	guanylate cyclase activity(GO:0004383)
0.4	1.5	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.4	1.9	GO:0004103	choline kinase activity(GO:0004103)
0.4	3.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.4	1.9	GO:0070051	fibrinogen binding(GO:0070051)
0.4	3.4	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4	1.1	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.4	23.8	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4	7.4	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4	1.4	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3	2.0	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3	2.0	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.3	2.2	GO:0008430	selenium binding(GO:0008430)
0.3	7.4	GO:0005112	Notch binding(GO:0005112)
0.3	0.9	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.3	3.0	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3	26.1	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.3	6.7	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.3	1.7	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.3	2.4	GO:0015232	heme transporter activity(GO:0015232)
0.3	5.0	GO:0031402	sodium ion binding(GO:0031402)
0.3	4.2	GO:0016595	glutamate binding(GO:0016595)
0.3	1.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.3	2.0	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.2	2.5	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.2	6.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.2	6.0	GO:0022829	wide pore channel activity(GO:0022829)
0.2	2.7	GO:0008131	primary amine oxidase activity(GO:0008131)
0.2	3.1	GO:0005542	folic acid binding(GO:0005542)
0.2	6.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.2	9.9	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.2	10.9	GO:0019842	vitamin binding(GO:0019842)
0.2	0.4	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.2	0.9	GO:0008312	7S RNA binding(GO:0008312)
0.2	4.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.2	1.7	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.2	1.9	GO:0042056	chemoattractant activity(GO:0042056)
0.2	5.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.2	0.6	GO:0036468	aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.2	2.9	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.2	12.3	GO:0005080	protein kinase C binding(GO:0005080)
0.2	0.6	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.2	3.0	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.2	1.6	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.2	4.1	GO:0005212	structural constituent of eye lens(GO:0005212)
0.2	2.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.2	1.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.2	0.8	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.2	3.6	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.2	0.4	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.2	2.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.2	0.7	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.2	2.3	GO:0008097	5S rRNA binding(GO:0008097)
0.2	1.7	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	4.8	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.2	1.5	GO:0005167	neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
0.2	2.5	GO:0008143	poly(A) binding(GO:0008143)
0.2	22.0	GO:0008083	growth factor activity(GO:0008083)
0.2	2.4	GO:0017171	serine hydrolase activity(GO:0017171)
0.2	4.0	GO:0042923	neuropeptide binding(GO:0042923)
0.2	3.2	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	2.9	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.9	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.1	2.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	3.7	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	1.1	GO:0001055	RNA polymerase II activity(GO:0001055)
0.1	0.9	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.2	GO:0070012	oligopeptidase activity(GO:0070012)
0.1	4.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	1.6	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.9	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1	1.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	8.5	GO:0020037	heme binding(GO:0020037) tetrapyrrole binding(GO:0046906)
0.1	1.8	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	1.4	GO:0004697	protein kinase C activity(GO:0004697)
0.1	9.7	GO:0016503	pheromone receptor activity(GO:0016503)
0.1	1.0	GO:0070402	NADPH binding(GO:0070402)
0.1	0.3	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	41.6	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.1	2.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	2.7	GO:0005109	frizzled binding(GO:0005109)
0.1	1.6	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	0.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.4	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.6	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.1	0.9	GO:0016854	racemase and epimerase activity(GO:0016854)
0.1	2.7	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1	14.2	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	1.8	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.1	0.4	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	1.0	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	4.2	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.7	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.8	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	1.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.4	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	1.6	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0008265	Mo-molybdopterin cofactor sulfurase activity(GO:0008265) molybdenum ion binding(GO:0030151)
0.0	0.5	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.5	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0033149	FFAT motif binding(GO:0033149)
0.0	1.2	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	1.4	GO:0043022	ribosome binding(GO:0043022)
0.0	0.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.5	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	10.4	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.6	GO:0008009	chemokine activity(GO:0008009)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.9	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.3	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	31.4	ST JAK STAT PATHWAY	Jak-STAT Pathway
2.0	2.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
1.4	2.9	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.1	53.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.9	23.6	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.9	27.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.7	37.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.6	36.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.5	4.2	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.4	106.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4	5.1	PID EPHA FWDPATHWAY	EPHA forward signaling
0.4	1.4	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.3	24.9	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.3	8.5	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	3.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.2	6.0	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.2	3.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.2	8.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.2	4.7	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.2	4.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.2	2.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2	3.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.2	2.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	3.4	PID RAS PATHWAY	Regulation of Ras family activation
0.1	2.6	PID REELIN PATHWAY	Reelin signaling pathway
0.1	3.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	3.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	0.4	PID EPO PATHWAY	EPO signaling pathway
0.1	2.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	1.9	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.1	1.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	2.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	1.6	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	1.9	PID FGF PATHWAY	FGF signaling pathway
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.4	PID IL23 PATHWAY	IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.0	47.9	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
7.6	143.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
2.4	21.9	REACTOME DEFENSINS	Genes involved in Defensins
2.3	34.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.7	18.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.6	32.9	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
1.5	11.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
1.5	24.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
1.4	24.0	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.4	19.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
1.4	52.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
1.3	86.6	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
1.0	8.1	REACTOME OPSINS	Genes involved in Opsins
1.0	12.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.9	2.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.9	10.8	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.8	61.1	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.7	10.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.7	19.2	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.7	6.0	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.7	11.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.6	12.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6	15.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.6	18.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.6	103.0	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.5	2.7	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.5	7.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.5	5.5	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.5	6.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.5	8.0	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.5	2.7	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.4	11.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.4	1.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.4	12.5	REACTOME KINESINS	Genes involved in Kinesins
0.4	5.6	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.4	2.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	10.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	18.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.3	3.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.3	11.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.3	16.3	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.3	5.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.3	3.0	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.3	11.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.3	5.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	4.9	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.3	4.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.3	3.9	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.3	1.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	2.7	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.2	4.1	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	2.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.2	5.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.2	6.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.2	2.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.2	3.0	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2	7.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	2.0	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.2	2.7	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.2	4.4	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.2	1.5	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.2	3.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.2	2.1	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	1.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.1	1.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	0.8	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.1	2.0	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	18.2	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	16.7	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	2.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	0.9	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	1.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	1.8	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	1.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	1.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.4	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.1	8.2	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	0.8	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	0.7	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	3.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.8	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.5	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	1.2	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	1.2	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.5	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters

Results for Pou1f1

Z-value: 2.14

Motif logo

Transcription factors associated with Pou1f1

Activity-expression correlation:

Activity profile of Pou1f1 motif

Sorted Z-values of Pou1f1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou1f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: