Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Pou2f1

Z-value: 1.00

Motif logo

Transcription factors associated with Pou2f1

Gene Symbol Gene ID Gene Info
ENSRNOG00000003581 POU class 2 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou2f1rn6_v1_chr13_-_84217332_842173660.481.5e-19Click!

Activity profile of Pou2f1 motif

Sorted Z-values of Pou2f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_57241968 30.60 ENSRNOT00000082191
lymphocyte cytosolic protein 1
chr6_-_143065639 30.59 ENSRNOT00000070923

chr4_+_106323089 29.02 ENSRNOT00000091402

chr2_+_223029559 27.55 ENSRNOT00000045584

chr4_+_98370797 24.55 ENSRNOT00000031991

chr6_+_139486775 23.41 ENSRNOT00000077771

chr3_+_16846412 23.06 ENSRNOT00000074266

chr6_-_142676432 22.55 ENSRNOT00000074947

chr10_+_45289741 21.58 ENSRNOT00000066190
histone cluster 3, H2ba
chr6_-_142880382 20.83 ENSRNOT00000074706
ENSRNOT00000072861

chr3_+_18315320 19.73 ENSRNOT00000006954

chr3_+_20641664 19.41 ENSRNOT00000044699

chr6_-_142353308 18.85 ENSRNOT00000066416

chr6_-_142585188 18.61 ENSRNOT00000067437

chr3_+_19274273 18.14 ENSRNOT00000040102

chr4_-_95970666 17.80 ENSRNOT00000008826
hematopoietic prostaglandin D synthase
chr6_-_141488290 17.40 ENSRNOT00000067336

chr4_-_103569159 17.12 ENSRNOT00000084036

chr14_-_15258207 16.78 ENSRNOT00000039383
C-X-C motif chemokine ligand 13
chr16_-_75481115 16.56 ENSRNOT00000035128
defensin alpha 7
chr6_-_143131118 16.17 ENSRNOT00000074930

chr3_+_20007192 15.90 ENSRNOT00000075229

chr4_+_93959152 15.77 ENSRNOT00000058437

chr17_+_44758460 15.76 ENSRNOT00000089436
histone cluster 1, H2an
chr3_+_17889972 15.68 ENSRNOT00000073021

chr8_-_114617466 15.33 ENSRNOT00000082992
ENSRNOT00000038160
collagen type VI alpha 5 chain
chr11_+_85532526 15.05 ENSRNOT00000036565

chr10_-_45297385 15.05 ENSRNOT00000041187
histone cluster 3 H2B family member b
chr7_-_18793289 14.88 ENSRNOT00000036375

chr3_-_16999720 14.88 ENSRNOT00000074382
similar to immunoglobulin kappa-chain VK-1
chr3_+_19441604 14.81 ENSRNOT00000090581

chr6_-_142933110 14.78 ENSRNOT00000046885

chr6_-_143702033 14.68 ENSRNOT00000051410

chr3_+_19045214 14.56 ENSRNOT00000070878

chr8_+_82038967 14.38 ENSRNOT00000079535
myosin VA
chr1_+_63734135 14.37 ENSRNOT00000084439
neutrophil immunoglobulin-like receptor-1
chr4_+_102665529 14.32 ENSRNOT00000082333

chr6_-_131926272 13.74 ENSRNOT00000084057
ENSRNOT00000088421
B-cell CLL/lymphoma 11B
chr3_+_19690016 13.73 ENSRNOT00000085460

chr4_-_69268336 13.31 ENSRNOT00000018042
protease, serine, 3B
chr3_+_20303979 13.13 ENSRNOT00000058331

chr3_+_17546566 12.84 ENSRNOT00000050825

chr5_-_169658875 12.72 ENSRNOT00000015840
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr17_-_44748188 12.60 ENSRNOT00000081970
histone H2A type 1-E
chr2_-_35104963 12.44 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr11_+_85042348 12.39 ENSRNOT00000042220

chr14_+_48768537 12.22 ENSRNOT00000082599
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_75319765 12.11 ENSRNOT00000085698
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr8_+_5606592 11.83 ENSRNOT00000011727
matrix metallopeptidase 12
chr2_+_186703541 11.57 ENSRNOT00000093342
Fc receptor-like 1
chr4_-_102124609 11.53 ENSRNOT00000048263

chr4_+_94696965 11.44 ENSRNOT00000064696
glutamate ionotropic receptor delta type subunit 2
chr8_-_49308806 11.37 ENSRNOT00000047291
CD3e molecule
chr3_+_17139670 11.35 ENSRNOT00000073316

chr4_+_101909389 11.29 ENSRNOT00000086458

chr6_-_54059119 10.66 ENSRNOT00000005521
histone deacetylase 9
chr4_+_102068556 10.57 ENSRNOT00000077412

chr5_+_152721940 10.55 ENSRNOT00000039322
aurora kinase A and ninein interacting protein
chr4_-_103761881 10.52 ENSRNOT00000084103

chr11_+_85992696 10.46 ENSRNOT00000084433

chr4_+_78496043 10.43 ENSRNOT00000059136
amine oxidase, copper containing 1
chr17_+_44738643 10.32 ENSRNOT00000087643
histone H2A type 1-like
chr6_-_99783047 10.18 ENSRNOT00000009028
spectrin, beta, erythrocytic
chr1_-_116153722 10.14 ENSRNOT00000041605
formyl peptide receptor 3
chr4_-_163762434 9.95 ENSRNOT00000081854
immunoreceptor Ly49si1
chr17_-_44738330 9.84 ENSRNOT00000072195
histone cluster 1, H2bd-like
chr11_+_85508300 9.69 ENSRNOT00000038646

chr9_+_8052210 9.49 ENSRNOT00000073659
adhesion G protein-coupled receptor E4
chr17_+_43632397 9.47 ENSRNOT00000013790
histone cluster 1, H2ah
chr4_+_101949285 9.16 ENSRNOT00000058446

chr9_+_8054466 9.04 ENSRNOT00000081513
adhesion G protein-coupled receptor E4
chr4_+_101687327 8.95 ENSRNOT00000082501

chr1_-_198486157 8.85 ENSRNOT00000022758
zymogen granule protein 16
chr4_-_162189994 8.71 ENSRNOT00000045501
similar to osteoclast inhibitory lectin
chr4_-_163049084 8.71 ENSRNOT00000091644
Cd69 molecule
chr1_+_188420461 8.69 ENSRNOT00000037870
centriolar coiled-coil protein 110
chr5_+_10178302 8.67 ENSRNOT00000009679
syntrophin, gamma 1
chr17_+_78764506 8.40 ENSRNOT00000077953
suppressor of variegation 3-9 homolog 2
chr6_-_143206772 8.38 ENSRNOT00000073713

chr1_+_114046478 8.34 ENSRNOT00000032254
sialic acid binding Ig-like lectin H
chr4_-_163423628 8.29 ENSRNOT00000079526
killer cell lectin-like receptor subfamily C, member 3
chr13_+_89386023 8.05 ENSRNOT00000086223
Fc fragment of IgG receptor IIIa
chr18_+_30474947 7.89 ENSRNOT00000027188
protocadherin beta 9
chr2_+_247299433 7.82 ENSRNOT00000050330
unc-5 netrin receptor C
chr1_+_227640680 7.77 ENSRNOT00000033613
membrane-spanning 4-domains, subfamily A, member 4C
chr14_-_28856214 7.74 ENSRNOT00000044659
adhesion G protein-coupled receptor L3
chr16_-_31301880 7.73 ENSRNOT00000084847
ENSRNOT00000083943

chr4_-_135069970 7.70 ENSRNOT00000008221
contactin 3
chr1_-_17378047 7.67 ENSRNOT00000020102
thymocyte selection associated
chr4_-_128266082 7.51 ENSRNOT00000039549
nucleoporin 50
chr17_-_31916553 7.43 ENSRNOT00000074220
uncharacterized LOC100911032
chr7_+_11356118 7.38 ENSRNOT00000041325
ATCAY, caytaxin
chr9_-_119869639 7.37 ENSRNOT00000080498
NDC80 kinetochore complex component
chr8_-_23148396 7.37 ENSRNOT00000075237
acid phosphatase 5, tartrate resistant
chr8_+_58347736 7.32 ENSRNOT00000080227
ENSRNOT00000066222
solute carrier family 35, member F2
chr4_+_101531378 7.32 ENSRNOT00000087546

chr2_-_41871858 7.18 ENSRNOT00000039720
Grb2-binding adaptor protein, transmembrane
chr10_+_42614713 7.15 ENSRNOT00000081136
ENSRNOT00000073148
glutamate ionotropic receptor AMPA type subunit 1
chr4_-_70628470 7.13 ENSRNOT00000029319
trypsin 5
chr8_+_107875991 7.10 ENSRNOT00000090299
DAZ interacting zinc finger protein 1-like
chr6_-_143768985 7.00 ENSRNOT00000046694
immunoglobulin heavy variable V15-2
chr1_+_156552328 7.00 ENSRNOT00000055401
discs large MAGUK scaffold protein 2
chr4_+_69457472 6.98 ENSRNOT00000067597
T cell receptor beta, variable 19
chr8_-_13906355 6.98 ENSRNOT00000029634
centrosomal protein 295
chr16_-_48921242 6.83 ENSRNOT00000041596
centromere protein U
chr5_+_122019301 6.81 ENSRNOT00000068158
phosphodiesterase 4B
chr3_+_19366370 6.72 ENSRNOT00000086557

chr15_-_34647421 6.70 ENSRNOT00000072426
mast cell protease 8
chr1_-_73226777 6.63 ENSRNOT00000025080
natural cytotoxicity triggering receptor 1
chr4_+_69138525 6.61 ENSRNOT00000073589
T cell receptor beta, variable 1
chr15_-_34694180 6.53 ENSRNOT00000079505
ENSRNOT00000027950
ENSRNOT00000079782
ENSRNOT00000080221
mast cell protease 8
chr4_-_108717309 6.51 ENSRNOT00000085062

chr3_-_7203420 6.49 ENSRNOT00000015236
growth factor independent 1B transcriptional repressor
chr15_-_34625121 6.48 ENSRNOT00000073555
mast cell protease 8-like 2
chr10_+_61685241 6.46 ENSRNOT00000092606
MAX network transcriptional repressor
chr2_-_250778269 6.43 ENSRNOT00000085670
ENSRNOT00000083535
ENSRNOT00000017824
chloride channel accessory 5
chr10_-_18574710 6.42 ENSRNOT00000079031
potassium voltage-gated channel interacting protein 1
chrX_+_96863891 6.39 ENSRNOT00000085665

chr4_-_164691405 6.38 ENSRNOT00000090979
ENSRNOT00000091932
ENSRNOT00000078219
Ly49 stimulatory receptor 4
Ly49 inhibitory receptor 2
chr6_-_141198565 6.38 ENSRNOT00000064361

chr20_+_4043741 6.33 ENSRNOT00000000525
RT1 class II, locus Bb
chr6_+_111076351 6.30 ENSRNOT00000089644
transmembrane protein 63c
chr16_+_39909270 6.29 ENSRNOT00000081994
WD repeat domain 17
chr14_-_21252538 6.24 ENSRNOT00000005003
ameloblastin
chr6_-_142060032 6.22 ENSRNOT00000064717

chr6_+_45683234 6.22 ENSRNOT00000052003
cytidine/uridine monophosphate kinase 2
chr8_+_39305128 6.20 ENSRNOT00000008285
fasciculation and elongation protein zeta 1
chr1_+_151439409 6.20 ENSRNOT00000022060
ENSRNOT00000050639
glutamate metabotropic receptor 5
chr2_-_165600748 6.15 ENSRNOT00000013216
intraflagellar transport 80
chr4_+_162437089 6.10 ENSRNOT00000038801
C-type lectin domain family 2 member D2
chr9_-_85243001 6.05 ENSRNOT00000020219
secretogranin II
chr9_+_92681078 6.01 ENSRNOT00000034152
SP100 nuclear antigen
chr4_-_165118062 5.95 ENSRNOT00000087219
Ly49s8
chr6_-_143537030 5.89 ENSRNOT00000071876
rCG64220-like
chr6_+_100337226 5.71 ENSRNOT00000011220
fucosyltransferase 8
chrX_+_118197217 5.62 ENSRNOT00000090922
5-hydroxytryptamine receptor 2C
chr18_+_30398113 5.59 ENSRNOT00000027206
protocadherin beta 5
chr5_-_150723321 5.57 ENSRNOT00000018038
ATPase inhibitory factor 1
chr18_+_30387937 5.57 ENSRNOT00000027210
protocadherin beta 4
chr2_-_184263564 5.55 ENSRNOT00000015279
F-box and WD repeat domain containing 7
chr9_+_91001828 5.40 ENSRNOT00000080956

chr15_+_32832035 5.35 ENSRNOT00000060250

chr4_+_147333056 5.33 ENSRNOT00000012137
peroxisome proliferator-activated receptor gamma
chr3_+_19205460 5.33 ENSRNOT00000070869
immunoglobulin kappa variable 4-80
chr11_+_42259761 5.30 ENSRNOT00000047310
Eph receptor A6
chr15_+_41643541 5.29 ENSRNOT00000019646
ADP-ribosylation factor like GTPase 11
chr3_-_173944396 5.29 ENSRNOT00000079019
synaptonemal complex protein 2
chr4_+_153330069 5.29 ENSRNOT00000015560
solute carrier family 25 member 18
chr1_-_62558033 5.27 ENSRNOT00000015520
zinc finger protein 40
chr14_+_48740190 5.23 ENSRNOT00000031638
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_+_44520537 5.21 ENSRNOT00000077985
histone cluster 1, H2ai-like2
chr8_-_21481735 5.14 ENSRNOT00000038069
zinc finger protein 426
chr13_-_49487892 5.11 ENSRNOT00000044972
neurofascin
chr2_-_173668555 5.10 ENSRNOT00000013452
serpin family I member 2
chr17_-_81002838 5.07 ENSRNOT00000089807
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr14_+_94590765 5.03 ENSRNOT00000072533
similar to similar to RIKEN cDNA 1700001E04
chr2_+_206392200 5.03 ENSRNOT00000026631
round spermatid basic protein 1
chrX_+_120901495 5.02 ENSRNOT00000040742
WD repeat domain 44
chr3_-_66335869 5.00 ENSRNOT00000079781
ENSRNOT00000043238
ENSRNOT00000073412
ENSRNOT00000057878
ENSRNOT00000079212
ceramide kinase-like
chr2_+_86891092 4.92 ENSRNOT00000077162
ENSRNOT00000083066
zinc finger protein 457-like
chr13_+_43850751 4.88 ENSRNOT00000004995
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr3_-_48831417 4.87 ENSRNOT00000009920
ENSRNOT00000085246
potassium voltage-gated channel subfamily H member 7
chr4_+_138269142 4.77 ENSRNOT00000007788
contactin 4
chrX_+_65566047 4.75 ENSRNOT00000092103
hephaestin
chr13_-_79890134 4.74 ENSRNOT00000083043
similar to hypothetical protein
chr2_-_140387505 4.71 ENSRNOT00000047635
E74-like factor 2
chr1_+_55219773 4.65 ENSRNOT00000041610
similar to putative protein kinase
chr6_+_22167919 4.64 ENSRNOT00000007655
NLR family, CARD domain containing 4
chr15_+_75067297 4.64 ENSRNOT00000057931
similar to 60S acidic ribosomal protein P2
chr12_-_23727535 4.57 ENSRNOT00000085911
ENSRNOT00000001950
deltex E3 ubiquitin ligase 2
chr6_-_76535517 4.57 ENSRNOT00000083857
Ral GTPase activating protein catalytic alpha subunit 1
chr4_+_136676254 4.55 ENSRNOT00000088070
contactin 6
chr9_+_110721322 4.52 ENSRNOT00000079170

chr19_-_914880 4.51 ENSRNOT00000017127
chemokine-like factor
chrX_+_65563122 4.47 ENSRNOT00000017312
hephaestin
chr4_+_31229913 4.47 ENSRNOT00000077134
ENSRNOT00000087897
sterile alpha motif domain containing 9-like
chr12_-_22021851 4.47 ENSRNOT00000039280
TSC22 domain family, member 4
chr2_-_173563273 4.46 ENSRNOT00000081423
zinc finger, B-box domain containing
chr13_+_57243877 4.46 ENSRNOT00000083693
potassium sodium-activated channel subfamily T member 2
chr7_+_78188912 4.43 ENSRNOT00000043079
regulating synaptic membrane exocytosis 2
chr4_+_136512201 4.39 ENSRNOT00000051645
contactin 6
chr15_+_31642169 4.34 ENSRNOT00000072362

chr13_+_48455923 4.31 ENSRNOT00000009280
Rab7b, member RAS oncogene family
chr7_+_44009069 4.29 ENSRNOT00000005523
MGAT4 family, member C
chr18_+_30890869 4.26 ENSRNOT00000060466
protocadherin gamma subfamily B, 6
chr7_+_48867664 4.24 ENSRNOT00000005862
PTPRF interacting protein alpha 2
chr2_-_170301348 4.22 ENSRNOT00000088131
sucrase-isomaltase
chr14_-_72025137 4.22 ENSRNOT00000080604
C1q and tumor necrosis factor related protein 7
chr6_+_97110158 4.21 ENSRNOT00000088430
synaptotagmin 16
chr4_-_11610518 4.16 ENSRNOT00000066643
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_+_163174487 4.15 ENSRNOT00000088108
C-type lectin domain family 9, member A
chr1_+_99561523 4.13 ENSRNOT00000038229
carcinoembryonic antigen-related cell adhesion molecule 18
chr9_+_1313209 4.09 ENSRNOT00000083387
TBC1 domain family, member 5
chr13_+_50873605 4.08 ENSRNOT00000004382
fibromodulin
chr3_-_147188929 4.07 ENSRNOT00000055455
RAD21 cohesin complex component like 1
chr9_-_9142339 4.06 ENSRNOT00000046852
similar to RIKEN cDNA 1700001E04
chr4_-_87873247 4.05 ENSRNOT00000044351
vomeronasal 1 receptor 77
chr2_-_157066781 4.04 ENSRNOT00000001187
similar to RalA binding protein 1
chr3_+_149466770 4.03 ENSRNOT00000065104
BPI fold containing family A, member 6
chr4_-_164899041 3.99 ENSRNOT00000090316
Ly49 inhibitory receptor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 17.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
4.2 16.8 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
3.6 14.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
3.0 11.8 GO:0072642 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
2.9 8.7 GO:0032053 ciliary basal body organization(GO:0032053)
2.5 7.4 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
2.3 13.7 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
2.1 6.2 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
2.1 6.2 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
2.0 30.6 GO:0051764 actin filament network formation(GO:0051639) actin crosslink formation(GO:0051764)
2.0 6.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
2.0 3.9 GO:0071226 cellular response to molecule of fungal origin(GO:0071226)
1.9 11.4 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.9 5.6 GO:0031583 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
1.9 5.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
1.8 5.3 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
1.7 6.6 GO:0009597 detection of virus(GO:0009597)
1.6 6.3 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
1.4 4.3 GO:0034499 late endosome to Golgi transport(GO:0034499)
1.4 5.7 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
1.4 5.6 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.4 13.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
1.3 4.0 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.3 7.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.3 3.9 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
1.3 12.7 GO:0070995 NADPH oxidation(GO:0070995)
1.2 7.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.2 3.6 GO:0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) dUMP metabolic process(GO:0046078)
1.2 7.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
1.2 7.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.1 6.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
1.1 5.3 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
1.1 8.4 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
1.0 3.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.0 5.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.0 2.9 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
1.0 3.8 GO:0006272 leading strand elongation(GO:0006272)
0.9 10.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.9 7.4 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.9 2.8 GO:0018343 protein farnesylation(GO:0018343)
0.9 2.7 GO:0072720 response to dithiothreitol(GO:0072720)
0.9 5.3 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.9 5.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.8 11.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.8 6.5 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.8 3.0 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.7 10.4 GO:0071420 cellular response to histamine(GO:0071420)
0.7 9.8 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.7 4.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.7 6.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.7 2.7 GO:0036394 amylase secretion(GO:0036394)
0.7 4.6 GO:0070269 pyroptosis(GO:0070269)
0.6 1.9 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.6 1.9 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.6 7.0 GO:0046710 GDP metabolic process(GO:0046710)
0.6 8.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.6 54.7 GO:0006342 chromatin silencing(GO:0006342)
0.6 2.8 GO:1990918 meiotic DNA recombinase assembly(GO:0000707) double-strand break repair involved in meiotic recombination(GO:1990918)
0.5 2.2 GO:1903999 negative regulation of eating behavior(GO:1903999) regulation of locomotor rhythm(GO:1904059)
0.5 1.6 GO:2000567 defense response to nematode(GO:0002215) memory T cell activation(GO:0035709) positive regulation of memory T cell differentiation(GO:0043382) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.5 6.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.5 2.8 GO:0030916 otic vesicle formation(GO:0030916)
0.5 7.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.4 4.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4 2.6 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.4 6.0 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.4 2.5 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.4 9.2 GO:0006825 copper ion transport(GO:0006825)
0.4 5.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 1.1 GO:1905218 cellular response to astaxanthin(GO:1905218)
0.4 4.1 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.4 10.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.4 5.8 GO:0043383 negative T cell selection(GO:0043383)
0.4 1.8 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 4.4 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.3 1.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.3 1.3 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3 30.4 GO:0006334 nucleosome assembly(GO:0006334)
0.3 1.7 GO:0051660 establishment of centrosome localization(GO:0051660)
0.3 5.9 GO:0045760 positive regulation of action potential(GO:0045760)
0.3 1.3 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.3 4.3 GO:0006999 nuclear pore organization(GO:0006999)
0.2 0.7 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.2 1.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 4.7 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.2 3.6 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.2 2.1 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.2 0.6 GO:1901295 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.2 3.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 1.4 GO:2000253 positive regulation of feeding behavior(GO:2000253) positive regulation of energy homeostasis(GO:2000507)
0.2 0.8 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.2 1.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 6.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 3.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 3.0 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.2 6.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 2.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 2.5 GO:0009750 response to fructose(GO:0009750)
0.1 3.3 GO:0048520 positive regulation of behavior(GO:0048520)
0.1 5.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 5.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 2.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 2.1 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 2.0 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 2.6 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.1 1.7 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.9 GO:0042073 intraciliary transport(GO:0042073)
0.1 2.1 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 19.5 GO:0007416 synapse assembly(GO:0007416)
0.1 0.7 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 7.4 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.1 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 1.4 GO:0051013 microtubule severing(GO:0051013)
0.1 3.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 9.0 GO:0051028 mRNA transport(GO:0051028)
0.1 1.7 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 3.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 0.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 1.4 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 4.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.7 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 1.4 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.1 0.5 GO:0071233 cellular response to leucine(GO:0071233)
0.1 1.1 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.4 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 6.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.7 GO:0038202 TORC1 signaling(GO:0038202)
0.1 0.8 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 6.3 GO:0042246 tissue regeneration(GO:0042246)
0.1 0.7 GO:0071675 positive regulation of macrophage chemotaxis(GO:0010759) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.1 2.6 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.1 4.6 GO:0006414 translational elongation(GO:0006414)
0.1 0.8 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 2.4 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 3.7 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 6.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 3.0 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.5 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.1 9.4 GO:0007051 spindle organization(GO:0007051)
0.1 4.1 GO:1902117 positive regulation of organelle assembly(GO:1902117)
0.1 3.9 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 1.0 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.5 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 3.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 5.9 GO:0007586 digestion(GO:0007586)
0.0 4.2 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 1.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 4.9 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 13.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.8 GO:0051310 metaphase plate congression(GO:0051310)
0.0 4.8 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.0 0.2 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 1.0 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 3.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.1 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 1.9 GO:0016579 protein deubiquitination(GO:0016579)
0.0 4.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 2.6 GO:2001234 negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.6 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 2.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.4 GO:0042642 actomyosin, myosin complex part(GO:0042642)
1.5 7.4 GO:0031262 condensed nuclear chromosome outer kinetochore(GO:0000942) Ndc80 complex(GO:0031262)
1.4 11.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.4 22.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.3 35.9 GO:0001891 phagocytic cup(GO:0001891)
1.3 8.9 GO:0060205 cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
1.1 5.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.0 3.1 GO:0044611 nuclear pore inner ring(GO:0044611)
1.0 5.1 GO:0097454 Schwann cell microvillus(GO:0097454)
1.0 10.2 GO:0014731 spectrin(GO:0008091) spectrin-associated cytoskeleton(GO:0014731)
0.9 4.6 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.9 85.8 GO:0000786 nucleosome(GO:0000786)
0.9 6.0 GO:0030870 Mre11 complex(GO:0030870)
0.7 4.4 GO:0044308 axonal spine(GO:0044308)
0.6 4.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.5 3.1 GO:0097441 basilar dendrite(GO:0097441)
0.5 4.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.5 3.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 4.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 2.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 6.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 6.0 GO:0031045 dense core granule(GO:0031045)
0.4 6.2 GO:0097449 astrocyte projection(GO:0097449)
0.4 5.3 GO:0000800 lateral element(GO:0000800)
0.3 6.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 12.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 3.9 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.3 4.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 1.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 6.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 2.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 1.7 GO:0031931 TORC1 complex(GO:0031931)
0.2 7.7 GO:0008180 COP9 signalosome(GO:0008180)
0.2 5.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 22.4 GO:0005814 centriole(GO:0005814)
0.2 11.4 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.2 1.0 GO:0002142 stereocilia ankle link complex(GO:0002142) periciliary membrane compartment(GO:1990075) USH2 complex(GO:1990696)
0.2 7.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 8.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 10.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.2 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 2.2 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.1 3.0 GO:0031082 BLOC complex(GO:0031082)
0.1 0.6 GO:0005606 laminin-1 complex(GO:0005606)
0.1 2.9 GO:0030673 axolemma(GO:0030673)
0.1 13.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 2.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 6.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 8.7 GO:0005643 nuclear pore(GO:0005643)
0.1 2.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 3.0 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 10.6 GO:0000922 spindle pole(GO:0000922)
0.1 4.2 GO:0005581 collagen trimer(GO:0005581)
0.1 3.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 4.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.0 GO:0005858 axonemal dynein complex(GO:0005858)
0.1 15.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 5.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 7.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 24.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 5.7 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.8 GO:0051233 spindle midzone(GO:0051233)
0.1 2.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 3.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 2.7 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 18.4 GO:0030424 axon(GO:0030424)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 4.1 GO:0010008 endosome membrane(GO:0010008)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 15.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 2.3 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.8 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
3.3 13.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
2.1 6.2 GO:0009041 uridylate kinase activity(GO:0009041)
1.9 5.6 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
1.9 3.7 GO:0015616 DNA translocase activity(GO:0015616)
1.9 5.6 GO:0016882 cyclo-ligase activity(GO:0016882)
1.7 10.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
1.6 8.0 GO:0019770 IgG receptor activity(GO:0019770)
1.6 7.8 GO:0005042 netrin receptor activity(GO:0005042)
1.6 6.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
1.5 9.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.5 7.4 GO:0001729 ceramide kinase activity(GO:0001729)
1.2 3.7 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
1.2 11.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.2 4.9 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
1.1 5.6 GO:0050816 phosphothreonine binding(GO:0050816)
1.1 5.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.0 4.2 GO:0070699 type II activin receptor binding(GO:0070699)
1.0 3.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.9 10.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.8 2.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.8 14.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.8 9.2 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.8 10.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.8 3.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.8 5.3 GO:0050692 DBD domain binding(GO:0050692)
0.8 6.0 GO:0070087 chromo shadow domain binding(GO:0070087)
0.7 7.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.7 5.3 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.6 12.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.6 11.4 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.6 5.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.5 1.6 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.5 5.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.5 6.3 GO:1990405 protein antigen binding(GO:1990405)
0.5 5.7 GO:0008417 fucosyltransferase activity(GO:0008417)
0.5 2.8 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.4 7.4 GO:0008199 ferric iron binding(GO:0008199)
0.4 1.3 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
0.4 2.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 2.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.4 3.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.4 8.9 GO:0005112 Notch binding(GO:0005112)
0.4 1.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 12.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 17.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 4.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 1.3 GO:0036004 GAF domain binding(GO:0036004)
0.3 2.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 17.1 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.3 4.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 1.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 4.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.3 1.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 5.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 2.7 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 76.4 GO:0030246 carbohydrate binding(GO:0030246)
0.2 6.0 GO:0042056 chemoattractant activity(GO:0042056)
0.2 8.2 GO:0030506 ankyrin binding(GO:0030506)
0.2 4.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 10.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 4.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 7.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 2.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.2 7.4 GO:0050699 WW domain binding(GO:0050699)
0.2 2.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.2 9.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 2.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2 2.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 2.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 2.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 11.8 GO:0005518 collagen binding(GO:0005518)
0.2 2.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 1.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 98.9 GO:0046982 protein heterodimerization activity(GO:0046982)
0.2 1.9 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 1.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 0.8 GO:0005131 growth hormone receptor binding(GO:0005131)
0.2 3.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 2.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 23.7 GO:0051015 actin filament binding(GO:0051015)
0.1 0.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 3.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.7 GO:0048156 tau protein binding(GO:0048156)
0.1 1.9 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.3 GO:0102390 mycophenolic acid acyl-glucuronide esterase activity(GO:0102390)
0.1 9.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 3.0 GO:0042605 peptide antigen binding(GO:0042605)
0.1 3.1 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.1 1.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 1.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 3.9 GO:0043022 ribosome binding(GO:0043022)
0.1 2.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 10.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 24.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 10.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 2.8 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 2.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 2.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 7.8 GO:0003682 chromatin binding(GO:0003682)
0.0 1.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0015929 hexosaminidase activity(GO:0015929)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.4 8.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4 17.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4 17.4 PID ARF6 PATHWAY Arf6 signaling events
0.3 11.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 15.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 7.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 20.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 15.1 PID NOTCH PATHWAY Notch signaling pathway
0.2 5.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 8.8 PID PLK1 PATHWAY PLK1 signaling events
0.2 5.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 4.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 3.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 23.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 8.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 2.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 4.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 3.8 PID E2F PATHWAY E2F transcription factor network
0.1 0.9 PID MYC PATHWAY C-MYC pathway
0.0 2.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 5.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 11.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.8 16.8 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.7 18.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.6 14.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 2.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 11.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.4 5.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.4 7.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.4 8.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 9.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 17.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 5.9 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.3 10.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 5.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.3 15.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 11.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 4.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 3.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 6.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 6.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 8.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 7.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 2.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 4.6 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.2 5.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 11.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 1.8 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 3.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 4.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 3.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 14.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 7.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.7 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 10.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 5.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 2.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules