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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Pou2f3

Z-value: 1.19

Motif logo

Transcription factors associated with Pou2f3

Gene Symbol Gene ID Gene Info
ENSRNOG00000009118 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou2f3rn6_v1_chr8_-_47494982_474949820.164.3e-03Click!

Activity profile of Pou2f3 motif

Sorted Z-values of Pou2f3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_18574909 37.29 ENSRNOT00000083090
potassium voltage-gated channel interacting protein 1
chr8_+_39305128 37.24 ENSRNOT00000008285
fasciculation and elongation protein zeta 1
chr1_+_27476375 36.80 ENSRNOT00000047224
ENSRNOT00000075427
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like
chr11_+_66316606 36.18 ENSRNOT00000041715
syntaxin binding protein 5-like
chr11_+_42259761 34.48 ENSRNOT00000047310
Eph receptor A6
chr16_+_78539489 28.42 ENSRNOT00000057897
CUB and Sushi multiple domains 1
chr16_-_39719187 28.19 ENSRNOT00000092971
glycoprotein m6a
chr4_-_11610518 27.32 ENSRNOT00000066643
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_+_80358211 27.19 ENSRNOT00000002519
somatostatin
chr3_-_44086006 22.79 ENSRNOT00000034449
ENSRNOT00000082604
ermin
chr3_-_105279462 21.94 ENSRNOT00000010679
secretogranin V
chr10_-_27366665 21.85 ENSRNOT00000004725
gamma-aminobutyric acid type A receptor alpha1 subunit
chr8_-_8524643 21.69 ENSRNOT00000009418
contactin 5
chr8_+_82043403 21.60 ENSRNOT00000091789
myosin VA
chr15_+_4850122 21.02 ENSRNOT00000071133
G protein subunit gamma 2
chr3_+_51687809 19.93 ENSRNOT00000087242
sodium voltage-gated channel alpha subunit 2
chr15_+_87886783 19.91 ENSRNOT00000065710
SLAIN motif family, member 1
chr16_+_3293599 19.51 ENSRNOT00000081999
ENSRNOT00000047118
ENSRNOT00000020427
ELKS/RAB6-interacting/CAST family member 2
chr10_-_59888198 18.81 ENSRNOT00000093482
ENSRNOT00000049311
ENSRNOT00000093230
aspartoacylase
chr14_+_84237520 18.57 ENSRNOT00000083580
galactose-3-O-sulfotransferase 1
chr3_+_58164931 18.49 ENSRNOT00000002078
distal-less homeobox 1
chr19_-_11326139 18.34 ENSRNOT00000025669
metallothionein 3
chr20_-_13142856 18.14 ENSRNOT00000001743
S100 calcium binding protein B
chr10_+_49259194 17.55 ENSRNOT00000091100
ENSRNOT00000004390
F-box and WD repeat domain containing 10
chr1_+_240355149 17.46 ENSRNOT00000018521
transient receptor potential cation channel, subfamily M, member 3
chr10_-_18574710 17.32 ENSRNOT00000079031
potassium voltage-gated channel interacting protein 1
chr11_+_58624198 17.09 ENSRNOT00000002091
growth associated protein 43
chr5_-_9381214 16.86 ENSRNOT00000039237
similar to RIKEN cDNA 3110035E14
chr4_+_24222500 16.24 ENSRNOT00000045346
zinc finger protein 804B
chr7_+_133856101 16.01 ENSRNOT00000038686
PDZ domain containing RING finger 4
chr10_-_66873948 15.92 ENSRNOT00000039261
ecotropic viral integration site 2A
chr1_-_24924918 15.80 ENSRNOT00000043416

chr3_-_92290919 15.77 ENSRNOT00000007077
four jointed box 1
chr7_-_70552897 15.77 ENSRNOT00000080594
kinesin family member 5A
chr18_-_24182012 15.76 ENSRNOT00000023594
synaptotagmin 4
chr15_-_65507968 15.69 ENSRNOT00000046240
calmodulin 2
chr7_-_13751271 15.21 ENSRNOT00000009931
solute carrier family 1 member 6
chr10_+_1920529 15.09 ENSRNOT00000072296
RIKEN cDNA A630010A05 gene
chr9_-_88816898 15.04 ENSRNOT00000083667
solute carrier family 19 member 3
chr7_+_44009069 14.92 ENSRNOT00000005523
MGAT4 family, member C
chr7_+_28654733 14.62 ENSRNOT00000006174
pro-melanin-concentrating hormone
chr17_+_23661429 14.58 ENSRNOT00000046523
phosphatase and actin regulator 1
chr2_+_69415057 14.31 ENSRNOT00000013152
cadherin 10
chr9_-_75528644 14.11 ENSRNOT00000019283
erb-b2 receptor tyrosine kinase 4
chr9_+_67774150 14.10 ENSRNOT00000091060
inducible T-cell co-stimulator
chr1_+_188420461 13.93 ENSRNOT00000037870
centriolar coiled-coil protein 110
chr3_-_114728410 13.83 ENSRNOT00000000181
glycine amidinotransferase
chr4_+_157726941 13.60 ENSRNOT00000025081
vesicle-associated membrane protein 1
chr19_+_387374 13.57 ENSRNOT00000075433
uncharacterized LOC102547811
chr9_-_45558993 13.47 ENSRNOT00000087866
ENSRNOT00000017714
carbohydrate sulfotransferase 10
chr10_-_56211891 13.00 ENSRNOT00000015076
ATPase Na+/K+ transporting subunit beta 2
chr16_+_2379480 12.98 ENSRNOT00000079215
dynein, axonemal, heavy chain 12
chr19_-_43596801 12.97 ENSRNOT00000025625
fatty acid 2-hydroxylase
chr1_-_101773508 12.93 ENSRNOT00000067430
sulfotransferase family 2B member 1
chr2_+_3662763 12.92 ENSRNOT00000017828
multiple C2 and transmembrane domain containing 1
chr4_+_136512201 12.91 ENSRNOT00000051645
contactin 6
chr18_+_57654290 12.87 ENSRNOT00000025892
5-hydroxytryptamine receptor 4
chr18_-_31109025 12.51 ENSRNOT00000026381
FCH and double SH3 domains 1
chr3_-_143192408 12.30 ENSRNOT00000006885
similar to cystatin E2
chr1_+_17602281 12.12 ENSRNOT00000075461
jouberin-like
chr3_-_63094177 11.94 ENSRNOT00000045862
phosphodiesterase 11A
chr3_+_69549673 11.78 ENSRNOT00000043974
zinc finger protein 804A
chr14_-_28967980 11.42 ENSRNOT00000048175
adhesion G protein-coupled receptor L3
chr3_+_19045214 10.97 ENSRNOT00000070878

chr5_+_122390522 10.96 ENSRNOT00000064567
SH3-domain GRB2-like (endophilin) interacting protein 1
chr4_+_110700403 10.72 ENSRNOT00000092379
leucine rich repeat transmembrane neuronal 4
chr3_-_52447622 10.68 ENSRNOT00000083552
sodium voltage-gated channel alpha subunit 1
chr1_+_73837944 10.58 ENSRNOT00000036413
leukocyte-associated immunoglobulin-like receptor 1
chr1_+_8310577 10.39 ENSRNOT00000015131
human immunodeficiency virus type I enhancer binding protein 2
chr2_+_104290726 10.34 ENSRNOT00000017387
DnaJ heat shock protein family (Hsp40) member C5 beta
chr2_+_186703541 10.26 ENSRNOT00000093342
Fc receptor-like 1
chr6_-_142903440 10.21 ENSRNOT00000075707

chr5_-_139921013 10.15 ENSRNOT00000079957
small ArfGAP2
chr4_+_70828894 9.47 ENSRNOT00000064892
T cell receptor beta, constant 2
chr5_-_153840178 9.46 ENSRNOT00000025075
NIPA-like domain containing 3
chr2_-_173563273 9.40 ENSRNOT00000081423
zinc finger, B-box domain containing
chr6_-_141488290 9.35 ENSRNOT00000067336

chr15_+_56666012 9.31 ENSRNOT00000013408
5-hydroxytryptamine receptor 2A
chrX_+_35869538 9.28 ENSRNOT00000058947
protein phosphatase with EF-hand domain 1
chr7_-_8060373 9.18 ENSRNOT00000071699
olfactory receptor 798
chr14_+_34389991 9.17 ENSRNOT00000002953
phosducin-like 2
chr6_-_142933110 9.12 ENSRNOT00000046885

chr3_-_138683318 8.91 ENSRNOT00000029701
double zinc ribbon and ankyrin repeat domains 1
chr8_+_80965255 8.89 ENSRNOT00000079508
WD repeat domain 72
chr17_+_47721977 8.88 ENSRNOT00000080800
amphiphysin-like
chr18_+_30474947 8.67 ENSRNOT00000027188
protocadherin beta 9
chr19_+_12097632 8.67 ENSRNOT00000049452
carboxylesterase 5A
chr16_-_75340360 8.59 ENSRNOT00000018501
defensin alpha 5
chr14_+_7171613 8.56 ENSRNOT00000081600
kelch-like family member 8
chr1_+_201901342 8.39 ENSRNOT00000036657
similar to synaptonemal complex protein 3
chr3_+_170996193 8.29 ENSRNOT00000008959
SPO11, initiator of meiotic double stranded breaks
chr16_-_75481115 8.20 ENSRNOT00000035128
defensin alpha 7
chr3_-_148312420 8.07 ENSRNOT00000047416
ENSRNOT00000081272
Bcl2-like 1
chr4_+_101645731 8.05 ENSRNOT00000087901

chr3_+_117422704 7.95 ENSRNOT00000085647
solute carrier family 12 member 1
chr13_-_76049363 7.94 ENSRNOT00000075865
ENSRNOT00000007455
BMP/retinoic acid inducible neural specific 2
chr6_-_143065639 7.86 ENSRNOT00000070923

chr2_+_116970344 7.80 ENSRNOT00000039603
EGF-like and EMI domain containing 1
chr1_-_189181901 7.75 ENSRNOT00000092022
glycoprotein 2
chr16_+_71242470 7.65 ENSRNOT00000030489
leucine zipper and EF-hand containing transmembrane protein 2
chr6_-_143702033 7.55 ENSRNOT00000051410

chr8_+_71547468 7.45 ENSRNOT00000042369
casein kinase 1, gamma 1
chr14_-_20816588 7.43 ENSRNOT00000033806
solute carrier family 4 member 4
chr14_+_22091777 7.42 ENSRNOT00000072483
sulfotransferase family 1D, member 1
chr3_-_148312791 7.42 ENSRNOT00000091419
Bcl2-like 1
chr9_-_65790347 7.29 ENSRNOT00000028506

chr15_-_29548400 7.26 ENSRNOT00000078176

chr18_+_29951094 7.21 ENSRNOT00000027402
protocadherin alpha-1-like
chr4_-_117111653 7.18 ENSRNOT00000057537
sideroflexin 5
chr14_+_22107416 7.15 ENSRNOT00000060179
ENSRNOT00000080114
sulfotransferase family 1D, member 1
chr17_+_43673294 7.12 ENSRNOT00000074109
histone cluster 2, H4
chr16_-_24951612 7.08 ENSRNOT00000018987
transketolase-like 2
chr10_+_30169257 7.03 ENSRNOT00000006436
ring finger protein 145
chrX_-_38468360 7.01 ENSRNOT00000045285
MAP7 domain containing 2
chrX_+_6791136 7.01 ENSRNOT00000003984
norrin-like
chr3_-_66279155 6.95 ENSRNOT00000079887
ceramide kinase-like
chr19_+_21541742 6.90 ENSRNOT00000021095
ENSRNOT00000042077
ATP binding cassette subfamily C member 12
chr4_-_140503412 6.89 ENSRNOT00000079266

chr3_+_101791337 6.89 ENSRNOT00000046937
solute carrier family 5 member 12
chr16_+_32457521 6.77 ENSRNOT00000083579
chloride voltage-gated channel 3
chr1_-_189182306 6.72 ENSRNOT00000021249
glycoprotein 2
chr2_-_154418629 6.57 ENSRNOT00000076274
ENSRNOT00000076165
phospholipase C, eta 1
chr18_+_86299463 6.57 ENSRNOT00000058152
CD226 molecule
chr3_+_17546566 6.53 ENSRNOT00000050825

chrX_+_96991658 6.53 ENSRNOT00000049969

chr9_+_10941613 6.51 ENSRNOT00000070794
semaphorin 6B
chr11_-_54344615 6.48 ENSRNOT00000090307
myosin, heavy chain 15
chr6_-_138744480 6.47 ENSRNOT00000089387

chr1_+_53531076 6.45 ENSRNOT00000018015
t-complex protein 10b
chr13_-_74740458 6.44 ENSRNOT00000006548
testis expressed 35
chr6_-_61405195 6.44 ENSRNOT00000008655
leucine rich repeat neuronal 3
chr2_-_154418920 6.40 ENSRNOT00000076326
phospholipase C, eta 1
chr4_-_69211671 6.32 ENSRNOT00000017852
preprotrypsinogen IV
chr13_+_48427038 6.27 ENSRNOT00000009241
cathepsin E
chr4_+_101639641 6.27 ENSRNOT00000058282

chr4_-_176294997 6.14 ENSRNOT00000015112
ENSRNOT00000051461
ENSRNOT00000000026
ENSRNOT00000039877
ENSRNOT00000049303
kidney specific organic anion transporter
chr6_-_142635763 6.10 ENSRNOT00000048908

chr9_-_63291350 5.97 ENSRNOT00000058831
heat shock transcription factor, Y linked 2
chr2_+_196304492 5.96 ENSRNOT00000028640
LysM domain containing 1
chr11_-_61287914 5.95 ENSRNOT00000086286
spindle and centriole associated protein 1
chr1_-_67134827 5.80 ENSRNOT00000045214
vomeronasal 1 receptor 45
chr1_+_199019289 5.75 ENSRNOT00000087142
phosphorylase kinase catalytic subunit gamma 2
chr2_+_92549479 5.65 ENSRNOT00000082912
GTPase activating protein testicular GAP1
chr1_+_219403970 5.60 ENSRNOT00000029607
protein tyrosine phosphatase, receptor type, C-associated protein
chr5_-_70463546 5.56 ENSRNOT00000043184

chr13_+_48426820 5.45 ENSRNOT00000048391
cathepsin E
chr6_-_99273033 5.44 ENSRNOT00000088808
testis expressed 21
chr8_-_96547568 5.42 ENSRNOT00000078343
similar to RIKEN cDNA 4930579C12 gene
chr4_+_148139528 5.41 ENSRNOT00000092594
ENSRNOT00000015620
ENSRNOT00000092613
WASH complex subunit 2C
chr2_+_186776644 5.32 ENSRNOT00000046778
Fc receptor-like 3
chr9_-_65736852 5.27 ENSRNOT00000087458
trafficking kinesin protein 2
chr15_-_27733785 5.26 ENSRNOT00000029488
cyclin B1 interacting protein 1
chr6_-_142676432 5.26 ENSRNOT00000074947

chr17_-_43821536 5.24 ENSRNOT00000072286
histone H4 variant H4-v.1
chr4_+_56748494 5.14 ENSRNOT00000065747
uncharacterized LOC103692087
chr1_-_22269831 5.13 ENSRNOT00000081804
syntaxin 7
chr1_+_66959610 5.13 ENSRNOT00000072122
ENSRNOT00000045994
vomeronasal 1 receptor 48
chr6_-_142372031 5.08 ENSRNOT00000063929

chr13_-_47623849 5.04 ENSRNOT00000006106
interleukin 24
chr6_-_143131118 4.94 ENSRNOT00000074930

chr14_-_6679878 4.88 ENSRNOT00000075989
ENSRNOT00000067875
secreted phosphoprotein 1
chr8_+_78872102 4.87 ENSRNOT00000090047
zinc finger protein 280D
chr2_+_27713880 4.87 ENSRNOT00000083143
glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
chr10_-_70220558 4.74 ENSRNOT00000041389
ENSRNOT00000076398
ENSRNOT00000076596
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr15_+_31642169 4.61 ENSRNOT00000072362

chrX_-_142248369 4.51 ENSRNOT00000091330
fibroblast growth factor 13
chr4_+_159410799 4.51 ENSRNOT00000079225
A-kinase anchoring protein 3
chr13_-_78521911 4.51 ENSRNOT00000087506
RAB GTPase activating protein 1-like
chr4_+_70776046 4.49 ENSRNOT00000040403
protease, serine 1
chr10_+_28449335 4.48 ENSRNOT00000029118
ATPase phospholipid transporting 10B (putative)
chr5_-_57896475 4.47 ENSRNOT00000017903
similar to testes development-related NYD-SP22 isoform 1
chr12_+_23514981 4.46 ENSRNOT00000001937
Prkr interacting protein 1 (IL11 inducible)
chr14_-_23604834 4.43 ENSRNOT00000002760
signal transducing adaptor family member 1
chr7_+_59200918 4.37 ENSRNOT00000085073
protein tyrosine phosphatase, receptor type, R
chr9_-_104870382 4.34 ENSRNOT00000084398
solute carrier organic anion transporter family, member 6d1
chr18_+_750776 4.34 ENSRNOT00000021981
zinc finger protein 136
chr16_-_54533871 4.32 ENSRNOT00000015144
disintegrin and metalloproteinase domain-containing protein 25-like
chr1_+_227640680 4.28 ENSRNOT00000033613
membrane-spanning 4-domains, subfamily A, member 4C
chr14_-_34177455 4.27 ENSRNOT00000059814
ENSRNOT00000091230
exocyst complex component 1
chrX_-_45000363 4.26 ENSRNOT00000035538
claudin 34E
chr8_-_17696989 4.26 ENSRNOT00000083752

chr4_+_52199416 4.22 ENSRNOT00000009537
sperm adhesion molecule 1
chr4_+_88328061 4.20 ENSRNOT00000084775
vomeronasal 1 receptor 87
chr4_+_87026530 4.17 ENSRNOT00000018425
AVL9 cell migration associated
chr13_+_88644520 4.17 ENSRNOT00000003979
spermatogenesis associated 46
chr2_+_206392200 4.15 ENSRNOT00000026631
round spermatid basic protein 1
chr20_+_11114164 4.11 ENSRNOT00000001602
1-acylglycerol-3-phosphate O-acyltransferase 3
chr20_-_6195463 4.05 ENSRNOT00000092474
peroxisomal, testis specific 1
chr20_+_3677474 4.04 ENSRNOT00000047663
metallothionein 1M
chr9_+_70059683 3.98 ENSRNOT00000016038
zinc finger, DBF-type containing 2
chr15_-_71779033 3.94 ENSRNOT00000017765
protocadherin 20
chr4_+_96449351 3.94 ENSRNOT00000091272
TNFAIP3 interacting protein 3
chr4_+_174692331 3.92 ENSRNOT00000011770
pleckstrin homology domain containing A5
chr9_-_104870225 3.91 ENSRNOT00000065171
solute carrier organic anion transporter family, member 6d1
chr16_-_48921242 3.91 ENSRNOT00000041596
centromere protein U
chrX_+_136488691 3.88 ENSRNOT00000093432
Rho GTPase activating protein 36
chr18_+_30424814 3.82 ENSRNOT00000073425
protocadherin beta 7
chr6_-_10592454 3.67 ENSRNOT00000020600
phosphatidylinositol glycan anchor biosynthesis, class F
chr6_-_138662365 3.64 ENSRNOT00000066209
ENSRNOT00000084892
immunoglobulin heavy constant mu
chr4_+_102068556 3.64 ENSRNOT00000077412

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 18.6 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
6.2 18.5 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
6.1 18.3 GO:0097213 regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214) regulation of hydrogen peroxide catabolic process(GO:2000295)
5.4 21.6 GO:0051643 endoplasmic reticulum localization(GO:0051643)
5.3 15.8 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
5.2 15.5 GO:1905218 cellular response to astaxanthin(GO:1905218)
5.0 15.0 GO:0071934 thiamine transmembrane transport(GO:0071934)
4.6 13.9 GO:0032053 ciliary basal body organization(GO:0032053)
3.9 27.5 GO:0000103 sulfate assimilation(GO:0000103)
3.9 27.3 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
3.7 14.6 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
3.6 14.5 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
3.5 13.8 GO:1990402 embryonic liver development(GO:1990402)
3.2 13.0 GO:1903288 positive regulation of potassium ion import(GO:1903288)
3.2 15.8 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
3.1 9.3 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
3.1 37.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
2.8 19.9 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
2.6 7.9 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
2.6 15.7 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
2.6 18.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
2.4 54.6 GO:0045760 positive regulation of action potential(GO:0045760)
2.3 11.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
2.2 13.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
2.2 6.6 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
1.8 7.2 GO:0015746 citrate transport(GO:0015746)
1.8 14.1 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.8 5.3 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
1.7 17.1 GO:0016198 axon choice point recognition(GO:0016198)
1.7 6.8 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
1.6 4.9 GO:0006710 androgen catabolic process(GO:0006710)
1.6 11.0 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
1.6 21.9 GO:0071420 cellular response to histamine(GO:0071420)
1.5 6.1 GO:0051958 methotrexate transport(GO:0051958)
1.5 10.7 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
1.5 4.4 GO:1904139 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.4 11.0 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.4 5.4 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
1.3 21.5 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
1.3 5.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
1.1 3.4 GO:0060383 positive regulation of DNA strand elongation(GO:0060383)
1.1 21.9 GO:0016486 peptide hormone processing(GO:0016486)
1.1 4.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.9 1.9 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.9 27.2 GO:0010447 response to acidic pH(GO:0010447)
0.9 2.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.9 6.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.9 11.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.9 15.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.9 5.3 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.9 16.7 GO:0002517 T cell tolerance induction(GO:0002517)
0.9 11.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.9 17.5 GO:0016048 detection of temperature stimulus(GO:0016048)
0.9 3.4 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.8 11.7 GO:0016540 protein autoprocessing(GO:0016540)
0.8 2.5 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.8 10.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.8 4.7 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.8 34.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.7 28.4 GO:0001964 startle response(GO:0001964)
0.7 12.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.7 2.2 GO:2000196 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) positive regulation of female gonad development(GO:2000196) negative regulation of eosinophil migration(GO:2000417)
0.7 9.5 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.7 2.0 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.7 5.3 GO:0051026 chiasma assembly(GO:0051026)
0.6 8.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.6 4.5 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.6 12.9 GO:0032098 regulation of appetite(GO:0032098)
0.6 1.9 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.6 6.9 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.6 33.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.6 13.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.6 15.8 GO:0010842 retina layer formation(GO:0010842)
0.6 2.9 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.6 2.8 GO:0035063 nuclear speck organization(GO:0035063)
0.5 4.9 GO:0002118 aggressive behavior(GO:0002118)
0.5 2.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.5 20.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.5 3.1 GO:0002503 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.5 1.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.4 8.5 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.4 3.9 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.4 8.6 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.4 13.5 GO:0007616 long-term memory(GO:0007616)
0.4 1.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.4 33.9 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.4 2.9 GO:0050957 equilibrioception(GO:0050957) righting reflex(GO:0060013)
0.4 1.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 12.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.3 4.3 GO:0051601 exocyst localization(GO:0051601)
0.3 2.0 GO:0001927 exocyst assembly(GO:0001927)
0.3 1.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3 42.0 GO:0007416 synapse assembly(GO:0007416)
0.3 2.1 GO:0051036 regulation of endosome size(GO:0051036)
0.3 2.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.3 3.0 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.3 2.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 2.8 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.3 6.7 GO:0045332 phospholipid translocation(GO:0045332)
0.2 1.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 0.7 GO:0009139 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.2 7.4 GO:0015701 bicarbonate transport(GO:0015701)
0.2 0.9 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 3.5 GO:0046599 regulation of centriole replication(GO:0046599)
0.2 2.5 GO:0045059 positive thymic T cell selection(GO:0045059)
0.2 4.5 GO:0030574 collagen catabolic process(GO:0030574)
0.2 30.2 GO:0008360 regulation of cell shape(GO:0008360)
0.2 18.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 2.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.9 GO:0001967 suckling behavior(GO:0001967)
0.2 2.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 6.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 14.6 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.2 1.8 GO:0042501 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) serine phosphorylation of STAT protein(GO:0042501)
0.2 4.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.7 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 2.4 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 6.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.5 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.9 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.2 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 4.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 5.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.4 GO:0006265 DNA topological change(GO:0006265)
0.1 1.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 7.0 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.1 3.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 2.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.1 1.3 GO:0032801 receptor catabolic process(GO:0032801)
0.1 2.6 GO:0046326 positive regulation of glucose import(GO:0046326)
0.1 10.3 GO:0007605 sensory perception of sound(GO:0007605)
0.1 0.7 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 3.0 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.1 13.3 GO:0007018 microtubule-based movement(GO:0007018)
0.1 9.5 GO:0007286 spermatid development(GO:0007286)
0.1 1.9 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 0.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 4.5 GO:0003014 renal system process(GO:0003014)
0.1 8.8 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.1 1.5 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 11.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.8 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 1.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.0 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 4.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.7 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.1 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.4 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0 3.2 GO:0006479 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 8.2 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 1.8 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 1.1 GO:0007586 digestion(GO:0007586)
0.0 3.3 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 3.4 GO:0007283 spermatogenesis(GO:0007283)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.6 GO:0042642 actomyosin, myosin complex part(GO:0042642)
4.5 13.6 GO:0035577 azurophil granule membrane(GO:0035577)
3.8 22.8 GO:0033269 internode region of axon(GO:0033269)
2.7 27.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.3 18.3 GO:0097450 astrocyte end-foot(GO:0097450)
2.2 15.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
2.1 17.1 GO:0032584 growth cone membrane(GO:0032584)
1.5 30.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.4 4.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
1.2 15.8 GO:0097449 astrocyte projection(GO:0097449)
1.2 4.7 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
1.1 15.8 GO:0035253 ciliary rootlet(GO:0035253)
1.1 13.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.0 21.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.8 5.6 GO:0071203 WASH complex(GO:0071203)
0.7 11.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.7 28.2 GO:0044295 axonal growth cone(GO:0044295)
0.6 1.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.6 9.3 GO:0070852 cell body fiber(GO:0070852)
0.6 1.8 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.5 56.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.5 53.3 GO:0031225 anchored component of membrane(GO:0031225)
0.5 6.0 GO:0060091 kinocilium(GO:0060091)
0.5 2.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.5 2.7 GO:0071817 MMXD complex(GO:0071817)
0.4 12.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 3.1 GO:0070820 tertiary granule(GO:0070820)
0.4 2.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.4 4.5 GO:0002177 manchette(GO:0002177)
0.4 4.8 GO:0042581 specific granule(GO:0042581)
0.4 21.1 GO:0048786 presynaptic active zone(GO:0048786)
0.4 6.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.4 6.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 10.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 3.4 GO:0070187 telosome(GO:0070187)
0.3 0.9 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.3 14.7 GO:0030286 dynein complex(GO:0030286)
0.3 2.4 GO:0061700 GATOR2 complex(GO:0061700)
0.2 1.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 16.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 3.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 7.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 1.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 7.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 19.4 GO:0005814 centriole(GO:0005814)
0.2 2.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 14.1 GO:0005901 caveola(GO:0005901)
0.1 10.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.9 GO:0060077 inhibitory synapse(GO:0060077)
0.1 2.8 GO:0031091 platelet alpha granule(GO:0031091)
0.1 40.2 GO:0005874 microtubule(GO:0005874)
0.1 22.1 GO:0001726 ruffle(GO:0001726)
0.1 6.5 GO:0016459 myosin complex(GO:0016459)
0.1 5.5 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.0 GO:0000145 exocyst(GO:0000145)
0.1 9.5 GO:0043204 perikaryon(GO:0043204)
0.1 3.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 1.9 GO:1990391 DNA repair complex(GO:1990391)
0.1 2.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 17.5 GO:0030141 secretory granule(GO:0030141)
0.1 0.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 20.2 GO:0043025 neuronal cell body(GO:0043025)
0.1 11.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 2.7 GO:0016592 mediator complex(GO:0016592)
0.1 8.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 57.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 0.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.3 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 8.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.7 GO:0000786 nucleosome(GO:0000786)
0.0 3.3 GO:0043209 myelin sheath(GO:0043209)
0.0 18.5 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 4.0 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 27.3 GO:0070699 type II activin receptor binding(GO:0070699)
6.3 18.8 GO:0019807 aspartoacylase activity(GO:0019807)
5.2 15.7 GO:0031997 N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
5.0 15.0 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) uptake transmembrane transporter activity(GO:0015563)
4.6 18.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
4.4 21.9 GO:0008503 benzodiazepine receptor activity(GO:0008503) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
4.3 13.0 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
4.3 12.9 GO:0050294 steroid sulfotransferase activity(GO:0050294)
4.3 17.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
3.2 15.8 GO:0030348 syntaxin-3 binding(GO:0030348)
3.1 9.3 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
2.6 7.9 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
2.6 15.5 GO:0051434 BH3 domain binding(GO:0051434)
2.4 14.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
2.3 6.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
2.1 8.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
2.0 18.1 GO:0050786 RAGE receptor binding(GO:0050786)
1.9 21.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.8 7.2 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
1.7 34.5 GO:0005003 ephrin receptor activity(GO:0005003)
1.7 11.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
1.7 18.3 GO:0046870 cadmium ion binding(GO:0046870)
1.6 14.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.5 6.1 GO:0015350 methotrexate transporter activity(GO:0015350)
1.5 4.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.4 7.0 GO:0001729 ceramide kinase activity(GO:0001729)
1.4 11.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.3 19.9 GO:0043522 leucine zipper domain binding(GO:0043522)
1.2 20.9 GO:0043008 ATP-dependent protein binding(GO:0043008)
1.1 37.2 GO:0043015 gamma-tubulin binding(GO:0043015)
1.0 15.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.0 15.2 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.9 13.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.9 2.7 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.9 6.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.8 3.4 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.8 2.5 GO:0008142 oxysterol binding(GO:0008142)
0.8 50.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.7 17.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.7 9.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.6 1.9 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.6 9.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.6 10.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.6 10.7 GO:0031402 sodium ion binding(GO:0031402)
0.6 2.3 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.6 1.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.6 2.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.5 5.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.5 6.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.5 10.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 1.9 GO:0008940 nitrate reductase activity(GO:0008940)
0.5 13.8 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.5 49.7 GO:0019905 syntaxin binding(GO:0019905)
0.4 12.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.4 17.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.4 14.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.4 7.4 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.4 1.8 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.3 3.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3 6.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 5.3 GO:0050811 GABA receptor binding(GO:0050811)
0.3 2.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.3 2.7 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 2.8 GO:0070097 delta-catenin binding(GO:0070097)
0.3 4.1 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.3 6.3 GO:0005112 Notch binding(GO:0005112)
0.3 13.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.2 3.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 1.4 GO:0003916 DNA topoisomerase activity(GO:0003916)
0.2 21.9 GO:0051082 unfolded protein binding(GO:0051082)
0.2 0.7 GO:0050145 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.2 4.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 4.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 6.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 14.7 GO:0003777 microtubule motor activity(GO:0003777)
0.2 6.5 GO:0003774 motor activity(GO:0003774)
0.2 2.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 3.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 2.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 4.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 11.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 1.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 4.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 19.8 GO:0005262 calcium channel activity(GO:0005262)
0.2 1.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 9.3 GO:0030145 manganese ion binding(GO:0030145)
0.2 20.9 GO:0005179 hormone activity(GO:0005179)
0.1 22.8 GO:0051015 actin filament binding(GO:0051015)
0.1 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 7.7 GO:0043022 ribosome binding(GO:0043022)
0.1 1.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 4.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.9 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 7.4 GO:0001948 glycoprotein binding(GO:0001948)
0.1 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 9.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 6.2 GO:0003823 antigen binding(GO:0003823)
0.1 5.6 GO:0002039 p53 binding(GO:0002039)
0.1 40.1 GO:0005509 calcium ion binding(GO:0005509)
0.1 16.5 GO:0005096 GTPase activator activity(GO:0005096)
0.1 11.0 GO:0008017 microtubule binding(GO:0008017)
0.1 11.8 GO:0042393 histone binding(GO:0042393)
0.1 26.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 2.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.7 GO:0098879 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
0.1 0.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 1.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.0 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 3.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 4.3 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 2.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 21.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
1.0 15.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.9 34.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.7 14.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.4 17.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 7.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.3 4.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 4.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 18.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 6.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 8.7 PID E2F PATHWAY E2F transcription factor network
0.1 6.0 PID NOTCH PATHWAY Notch signaling pathway
0.1 0.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.3 PID AURORA B PATHWAY Aurora B signaling
0.0 12.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 22.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
1.3 15.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.3 18.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.3 21.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.2 18.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
1.1 27.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
1.0 12.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
1.0 27.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
1.0 8.6 REACTOME DEFENSINS Genes involved in Defensins
0.9 21.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.8 14.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.8 15.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.8 13.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.7 19.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 15.8 REACTOME KINESINS Genes involved in Kinesins
0.5 14.1 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.5 14.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.5 13.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 10.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.4 2.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 7.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.3 16.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.3 2.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 14.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.2 2.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 8.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 3.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 12.9 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.2 32.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 4.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 6.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 2.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 5.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 2.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 4.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 4.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.4 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 2.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 4.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 6.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT