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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Rhox11

Z-value: 0.83

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Transcription factors associated with Rhox11

Gene Symbol Gene ID Gene Info
Rhox11
ENSRNOG00000028044 reproductive homeobox 11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rhox11rn6_v1_chrX_+_124228270_124228270-0.027.1e-01Click!

Activity profile of Rhox11 motif

Sorted Z-values of Rhox11 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_72272248 37.40 ENSRNOT00000003908
Car4
carbonic anhydrase 4
chr18_+_70548607 32.45 ENSRNOT00000085318
Myo5b
myosin Vb
chr4_+_168832910 25.14 ENSRNOT00000011134
Gprc5a
G protein-coupled receptor, class C, group 5, member A
chr5_+_119727839 18.17 ENSRNOT00000014354
Cachd1
cache domain containing 1
chr14_+_109533792 16.72 ENSRNOT00000067690
LOC108348154
ankyrin repeat domain-containing protein 29-like
chr5_-_138462864 16.58 ENSRNOT00000011325
Ccdc30
coiled-coil domain containing 30
chr20_+_46044892 15.51 ENSRNOT00000057187
Ak9
adenylate kinase 9
chr9_-_30321323 15.28 ENSRNOT00000018234
Fam135a
family with sequence similarity 135, member A
chr13_+_47454591 14.83 ENSRNOT00000005791
LOC498222
similar to specifically androgen-regulated protein
chr6_-_49324450 14.65 ENSRNOT00000066904
Sntg2
syntrophin, gamma 2
chr8_-_14880644 14.49 ENSRNOT00000015977
Fat3
FAT atypical cadherin 3
chr1_+_33910912 13.97 ENSRNOT00000044690
Irx1
iroquois homeobox 1
chr6_-_88917070 13.53 ENSRNOT00000000767
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chrX_+_35599258 13.08 ENSRNOT00000072627
ENSRNOT00000005061
Cdkl5
cyclin-dependent kinase-like 5
chr2_-_183213228 12.78 ENSRNOT00000067618
Trim2
tripartite motif-containing 2
chr13_-_80862963 12.65 ENSRNOT00000004864
Fmo3
flavin containing monooxygenase 3
chr14_-_77810147 11.80 ENSRNOT00000035427
Cytl1
cytokine like 1
chrX_-_40086870 11.55 ENSRNOT00000010027
Smpx
small muscle protein, X-linked
chr9_-_91683468 11.15 ENSRNOT00000041550
Pid1
phosphotyrosine interaction domain containing 1
chr3_+_56355431 11.14 ENSRNOT00000037188
Myo3b
myosin IIIB
chr5_+_74727494 10.71 ENSRNOT00000076683
Rn50_5_0791.1

chr19_+_38422164 10.65 ENSRNOT00000017174
Nqo1
NAD(P)H quinone dehydrogenase 1
chr2_+_252090669 10.29 ENSRNOT00000020656
Lpar3
lysophosphatidic acid receptor 3
chr2_+_55747318 10.25 ENSRNOT00000050655
Dab2
DAB2, clathrin adaptor protein
chr2_+_3662763 10.03 ENSRNOT00000017828
Mctp1
multiple C2 and transmembrane domain containing 1
chr4_+_174692331 9.72 ENSRNOT00000011770
Plekha5
pleckstrin homology domain containing A5
chr2_-_18531210 9.68 ENSRNOT00000088313
Vcan
versican
chr1_-_52962388 9.56 ENSRNOT00000033685
T2
brachyury 2
chr3_+_2262253 9.45 ENSRNOT00000042100
ENSRNOT00000061303
ENSRNOT00000048137
ENSRNOT00000048353
ENSRNOT00000012129
Nsmf
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr4_-_14490446 9.43 ENSRNOT00000009132
Sema3c
semaphorin 3C
chr1_+_156552328 8.50 ENSRNOT00000055401
Dlg2
discs large MAGUK scaffold protein 2
chr8_-_53816447 8.41 ENSRNOT00000011454
Ttc12
tetratricopeptide repeat domain 12
chr18_+_30527705 8.39 ENSRNOT00000027168
Pcdhb14
protocadherin beta 14
chr3_+_35175313 8.38 ENSRNOT00000081744
Kif5c
kinesin family member 5C
chr17_+_89452814 8.26 ENSRNOT00000058760
RGD1561231
similar to MAP/microtubule affinity-regulating kinase 4 (MAP/microtubule affinity-regulating kinase like 1)
chr20_+_26893016 7.96 ENSRNOT00000082430
Dnajc12
DnaJ heat shock protein family (Hsp40) member C12
chr1_+_166428761 7.95 ENSRNOT00000085555
Stard10
StAR-related lipid transfer domain containing 10
chr11_-_35749464 7.78 ENSRNOT00000078818
ENSRNOT00000078425
Erg
ERG, ETS transcription factor
chrX_+_908044 7.77 ENSRNOT00000072087
Zfp300
zinc finger protein 300
chr1_+_234252757 7.77 ENSRNOT00000091814
Rorb
RAR-related orphan receptor B
chr3_-_52510507 7.17 ENSRNOT00000091259
Scn1a
sodium voltage-gated channel alpha subunit 1
chr1_-_47477524 6.80 ENSRNOT00000067916
Rsph3
radial spoke 3 homolog
chr7_+_71572941 6.77 ENSRNOT00000007255
Sdc2
syndecan 2
chr1_-_81846804 6.20 ENSRNOT00000027435
Rabac1
Rab acceptor 1
chr1_-_252808380 6.18 ENSRNOT00000025856
Ch25h
cholesterol 25-hydroxylase
chr16_-_7406951 5.75 ENSRNOT00000066508
Dnah1
dynein, axonemal, heavy chain 1
chr8_-_84506328 5.74 ENSRNOT00000064754
Mlip
muscular LMNA-interacting protein
chr6_-_135939534 5.66 ENSRNOT00000052237
Diras3
DIRAS family GTPase 3
chr7_+_15422479 5.44 ENSRNOT00000066520
Zfp563
zinc finger protein 563
chr2_-_84436912 5.23 ENSRNOT00000059565
Ankrd33b
ankyrin repeat domain 33B
chr16_+_69048730 5.10 ENSRNOT00000086082
ENSRNOT00000078128
Rab11fip1
RAB11 family interacting protein 1
chr3_+_8547349 5.08 ENSRNOT00000079108
ENSRNOT00000091697
Sptan1
spectrin, alpha, non-erythrocytic 1
chr1_-_146289465 4.97 ENSRNOT00000017362
Abhd17c
abhydrolase domain containing 17C
chr5_-_153840178 4.95 ENSRNOT00000025075
Nipal3
NIPA-like domain containing 3
chr1_-_266914093 4.69 ENSRNOT00000027526
Calhm2
calcium homeostasis modulator 2
chr6_-_3395954 4.68 ENSRNOT00000078044
Map4k3
mitogen-activated protein kinase kinase kinase kinase 3
chr9_-_78969013 4.66 ENSRNOT00000019772
ENSRNOT00000057585
Fn1
fibronectin 1
chr9_+_30419001 4.63 ENSRNOT00000018116
Col9a1
collagen type IX alpha 1 chain
chr2_-_84437084 4.42 ENSRNOT00000077598
Ankrd33b
ankyrin repeat domain 33B
chr14_+_113867209 4.42 ENSRNOT00000067591
Ccdc88a
coiled coil domain containing 88A
chr7_-_135850542 4.42 ENSRNOT00000038032
Twf1
twinfilin actin-binding protein 1
chr4_-_165192647 4.08 ENSRNOT00000086461
Klra5
killer cell lectin-like receptor, subfamily A, member 5
chr6_+_8669722 3.99 ENSRNOT00000048550
Camkmt
calmodulin-lysine N-methyltransferase
chr3_+_153491151 3.96 ENSRNOT00000047047
Manbal
mannosidase beta like
chr5_+_104941066 3.86 ENSRNOT00000009225
Rraga
Ras-related GTP binding A
chr13_+_87986240 3.45 ENSRNOT00000003705
Rgs5
regulator of G-protein signaling 5
chr3_-_120373500 3.37 ENSRNOT00000067727
Nphp1
nephrocystin 1
chr11_+_71151132 3.33 ENSRNOT00000082594
ENSRNOT00000082435
Rubcn
RUN and cysteine rich domain containing beclin 1 interacting protein
chr3_-_21027947 3.32 ENSRNOT00000051973
Olr421
olfactory receptor 421
chr5_-_107505454 3.17 ENSRNOT00000051752
Ifna11
interferon alpha family, gene 11
chr9_+_95274707 3.15 ENSRNOT00000045163
Ugt1a5
UDP glucuronosyltransferase family 1 member A5
chr20_+_27975549 2.91 ENSRNOT00000092075
Lims1
LIM zinc finger domain containing 1
chr5_-_59149625 2.88 ENSRNOT00000040641
ENSRNOT00000084216
Spag8
sperm associated antigen 8
chr4_+_117780533 2.70 ENSRNOT00000021211
Tprkb
Tp53rk binding protein
chr4_+_45034123 2.66 ENSRNOT00000078255
ST7
suppression of tumorigenicity 7
chr2_-_178521038 2.64 ENSRNOT00000033107
Rxfp1
relaxin/insulin-like family peptide receptor 1
chr3_-_21061070 2.62 ENSRNOT00000044461
Olr422
olfactory receptor 422
chr18_+_58325319 2.61 ENSRNOT00000065802
ENSRNOT00000077726
Napg
NSF attachment protein gamma
chr8_-_113937097 2.59 ENSRNOT00000046816
Nek11
NIMA-related kinase 11
chr13_-_15395617 2.59 ENSRNOT00000046060
LOC304725
similar to contactin associated protein-like 5 isoform 1
chrM_+_3904 2.56 ENSRNOT00000040993
Mt-nd2
mitochondrially encoded NADH dehydrogenase 2
chr2_-_199354793 2.56 ENSRNOT00000023548
Bcl9
B-cell CLL/lymphoma 9
chr7_+_18120715 2.52 ENSRNOT00000068151
Vom1r108
vomeronasal 1 receptor 108
chr19_+_14459450 2.47 ENSRNOT00000079257
Zfp82
zinc finger protein 82
chr3_+_67849966 2.47 ENSRNOT00000057826
Dusp19
dual specificity phosphatase 19
chr4_-_9060554 2.36 ENSRNOT00000046248
AABR07059215.1

chr1_-_67134827 2.32 ENSRNOT00000045214
Vom1r45
vomeronasal 1 receptor 45
chr5_+_141530211 2.30 ENSRNOT00000056546
4933427I04Rik
Riken cDNA 4933427I04 gene
chr2_-_261402880 2.25 ENSRNOT00000052396
ENSRNOT00000077839
ENSRNOT00000088561
Fpgt
fucose-1-phosphate guanylyltransferase
chr2_+_266141581 2.20 ENSRNOT00000078187
ENSRNOT00000051951
Rpe65
RPE65, retinoid isomerohydrolase
chr1_-_149633029 2.14 ENSRNOT00000048861
LOC100910049
olfactory receptor 14A2-like
chr3_-_43117337 2.09 ENSRNOT00000078001
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr5_+_118574801 2.05 ENSRNOT00000035949
Ube2u
ubiquitin-conjugating enzyme E2U (putative)
chr2_-_122756842 2.04 ENSRNOT00000080181
Ccdc144b
coiled-coil domain containing 144B
chrX_-_18890090 2.03 ENSRNOT00000041039
Klf8
Kruppel-like factor 8
chr4_-_121565212 1.93 ENSRNOT00000088753
Chchd6
coiled-coil-helix-coiled-coil-helix domain containing 6
chr20_-_46044738 1.80 ENSRNOT00000000343
Fig4
FIG4 phosphoinositide 5-phosphatase
chr12_-_50404550 1.77 ENSRNOT00000073072
Crybb1
crystallin, beta B1
chrX_+_65800059 1.75 ENSRNOT00000076428
Gpr165
G protein-coupled receptor 165
chr3_+_21114856 1.73 ENSRNOT00000044947
Olr423
olfactory receptor 423
chr1_+_61268248 1.66 ENSRNOT00000082730
LOC102552527
zinc finger protein 420-like
chr4_+_113782206 1.64 ENSRNOT00000009701
M1ap
meiosis 1 associated protein
chr1_-_67284864 1.62 ENSRNOT00000082908
LOC691661
similar to zinc finger and SCAN domain containing 4
chr7_+_23012070 1.49 ENSRNOT00000042460
LOC300308
similar to hypothetical protein 4930509O22
chr2_-_88314254 1.47 ENSRNOT00000038546
Car13
carbonic anhydrase 13
chr3_-_161272460 1.38 ENSRNOT00000020740
Acot8
acyl-CoA thioesterase 8
chr8_-_71337746 1.32 ENSRNOT00000021554
Zfp609
zinc finger protein 609
chr11_+_38035450 1.26 ENSRNOT00000083067
Mx2
MX dynamin like GTPase 2
chr9_-_113846053 1.06 ENSRNOT00000017253
LOC100910483
ankyrin repeat domain-containing protein 12-like
chr1_+_64031859 1.03 ENSRNOT00000090873
Mboat7l1
membrane bound O-acyltransferase domain containing 7-like 1
chr1_+_226030938 1.02 ENSRNOT00000030919
Fth1
ferritin heavy chain 1
chr3_+_72080630 1.01 ENSRNOT00000008911
Med19
mediator complex subunit 19
chr12_+_38368693 0.96 ENSRNOT00000083261
Clip1
CAP-GLY domain containing linker protein 1
chr7_-_3707226 0.88 ENSRNOT00000064380
Olr879
olfactory receptor 879
chr17_-_89838986 0.84 ENSRNOT00000081249
LOC108348078
ATP-dependent zinc metalloprotease YME1L1
chr11_-_38420032 0.80 ENSRNOT00000002209
ENSRNOT00000080681
C2cd2
C2 calcium-dependent domain containing 2
chr3_-_153454160 0.78 ENSRNOT00000010298
Ghrh
growth hormone releasing hormone
chr3_-_73401074 0.77 ENSRNOT00000012848
Olr476
olfactory receptor 476
chr17_-_78561613 0.77 ENSRNOT00000020220
Fam107b
family with sequence similarity 107, member B
chr5_-_78183122 0.76 ENSRNOT00000002083
ENSRNOT00000067076
Fkbp15
FK506 binding protein 15
chr10_+_109894286 0.70 ENSRNOT00000082209
Lrrc45
leucine rich repeat containing 45
chr3_+_75712483 0.67 ENSRNOT00000049264
Olr575
olfactory receptor 575
chr1_+_168546059 0.67 ENSRNOT00000086124
Olr101
olfactory receptor 101
chr20_+_3363737 0.65 ENSRNOT00000079654
Atat1
alpha tubulin acetyltransferase 1
chr14_+_82350734 0.63 ENSRNOT00000023259
Tmem129
transmembrane protein 129
chr9_-_52401660 0.57 ENSRNOT00000049387
Vom1r50
vomeronasal 1 receptor 50
chr1_+_84679614 0.56 ENSRNOT00000025581
AABR07002774.1

chr3_+_73115052 0.50 ENSRNOT00000090772
Olr454
olfactory receptor 454
chr11_-_81379871 0.47 ENSRNOT00000089294
Eif4a2
eukaryotic translation initiation factor 4A2
chr5_-_138222534 0.45 ENSRNOT00000009691
Zfp691
zinc finger protein 691
chrX_-_17252877 0.35 ENSRNOT00000060213
LOC102547118
retinitis pigmentosa 1-like 1 protein-like
chr4_-_163445136 0.29 ENSRNOT00000080299
Klrc3
killer cell lectin-like receptor subfamily C, member 3
chr15_-_103340239 0.29 ENSRNOT00000067309
ENSRNOT00000088909
Tgds
TDP-glucose 4,6-dehydratase
chr16_-_59721227 0.28 ENSRNOT00000015166
Prag1
PEAK1 related kinase activating pseudokinase 1
chr7_+_24638208 0.23 ENSRNOT00000009135
Mterf2
mitochondrial transcription termination factor 2
chr2_+_263212051 0.22 ENSRNOT00000089396
Negr1
neuronal growth regulator 1
chr3_+_1452644 0.19 ENSRNOT00000007949
Il1rn
interleukin 1 receptor antagonist
chr16_-_19225037 0.18 ENSRNOT00000019052
Klf2
Kruppel-like factor 2
chr8_+_41247536 0.12 ENSRNOT00000073027
Olr1219
olfactory receptor 1219
chr1_-_264794938 0.11 ENSRNOT00000043623
Pdzd7
PDZ domain containing 7
chr9_-_97151832 0.11 ENSRNOT00000040169
Asb18
ankyrin repeat and SOCS box-containing 18
chr8_-_77599781 0.03 ENSRNOT00000087980
Aqp9
aquaporin 9
chr1_-_199655147 0.03 ENSRNOT00000026979
LOC103691238
zinc finger protein 239-like
chrX_+_23414354 0.02 ENSRNOT00000031235
Cldn34a
claudin 34A

Network of associatons between targets according to the STRING database.

First level regulatory network of Rhox11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 32.5 GO:0032439 endosome localization(GO:0032439)
5.2 15.5 GO:0009216 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) dGDP metabolic process(GO:0046066)
3.5 14.0 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
3.4 10.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
2.8 11.2 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
2.4 9.4 GO:0003350 pulmonary myocardium development(GO:0003350)
2.1 8.4 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
2.1 25.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
1.6 4.7 GO:2001201 calcium-independent cell-matrix adhesion(GO:0007161) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) regulation of transforming growth factor-beta secretion(GO:2001201)
1.5 4.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
1.3 7.8 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
1.1 3.4 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
1.1 3.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
1.1 37.4 GO:0015701 bicarbonate transport(GO:0015701)
1.0 7.9 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.9 8.5 GO:0046710 GDP metabolic process(GO:0046710)
0.9 5.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.8 3.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.7 2.2 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.7 7.8 GO:0046549 retinal rod cell development(GO:0046548) retinal cone cell development(GO:0046549)
0.6 6.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.6 11.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.6 14.5 GO:0010842 retina layer formation(GO:0010842)
0.6 4.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.6 7.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.5 8.4 GO:0032060 bleb assembly(GO:0032060)
0.5 9.4 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.4 2.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.4 2.9 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.4 5.8 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.4 5.0 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.3 3.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.3 12.6 GO:0017144 drug metabolic process(GO:0017144)
0.3 10.6 GO:0019430 removal of superoxide radicals(GO:0019430)
0.3 13.5 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.3 1.8 GO:0031642 negative regulation of myelination(GO:0031642)
0.3 4.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 3.2 GO:0033141 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.3 11.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 1.3 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2 1.6 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.2 4.6 GO:0003417 growth plate cartilage development(GO:0003417)
0.2 0.7 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.2 5.7 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.2 6.8 GO:0031000 response to caffeine(GO:0031000)
0.2 13.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.2 1.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 9.7 GO:0008347 glial cell migration(GO:0008347)
0.2 2.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 2.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 1.9 GO:0042407 cristae formation(GO:0042407)
0.1 0.8 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 2.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.4 GO:0016559 peroxisome fission(GO:0016559)
0.1 5.1 GO:0051693 actin filament capping(GO:0051693)
0.1 2.6 GO:0007567 parturition(GO:0007567)
0.1 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 1.0 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 3.4 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 11.6 GO:0006941 striated muscle contraction(GO:0006941)
0.1 8.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 4.1 GO:0030101 natural killer cell activation(GO:0030101)
0.0 12.7 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 2.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 2.0 GO:0016574 histone ubiquitination(GO:0016574)
0.0 1.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 2.9 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.2 GO:0071499 cellular response to laminar fluid shear stress(GO:0071499)
0.0 3.4 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 8.0 GO:0061458 reproductive system development(GO:0061458)
0.0 1.8 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 11.1 GO:0044255 cellular lipid metabolic process(GO:0044255)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 32.5 GO:0045179 apical cortex(GO:0045179)
2.6 10.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
2.3 11.6 GO:0005927 muscle tendon junction(GO:0005927)
2.1 37.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.5 4.6 GO:0005594 collagen type IX trimer(GO:0005594)
1.4 5.8 GO:0036156 inner dynein arm(GO:0036156)
1.1 13.1 GO:0044294 dendritic growth cone(GO:0044294)
0.8 11.1 GO:0032426 stereocilium tip(GO:0032426)
0.8 3.9 GO:1990130 Iml1 complex(GO:1990130)
0.6 7.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.6 4.7 GO:0005577 fibrinogen complex(GO:0005577)
0.6 5.1 GO:0032437 cuticular plate(GO:0032437)
0.6 8.4 GO:0035253 ciliary rootlet(GO:0035253)
0.5 8.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.5 2.0 GO:0033503 HULC complex(GO:0033503)
0.4 7.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 9.4 GO:0097440 apical dendrite(GO:0097440)
0.3 1.9 GO:0061617 MICOS complex(GO:0061617)
0.2 0.7 GO:0097427 microtubule bundle(GO:0097427)
0.2 13.7 GO:0031225 anchored component of membrane(GO:0031225)
0.2 5.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 3.4 GO:0097546 ciliary base(GO:0097546)
0.1 1.0 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.0 GO:0044754 autolysosome(GO:0044754)
0.1 1.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 5.7 GO:0016605 PML body(GO:0016605)
0.1 2.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 4.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 4.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.5 GO:0031201 SNARE complex(GO:0031201)
0.0 32.7 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 7.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.1 GO:1990696 USH2 complex(GO:1990696)
0.0 9.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 18.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 3.3 GO:0005770 late endosome(GO:0005770)
0.0 18.6 GO:0005730 nucleolus(GO:0005730)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.8 GO:0030426 growth cone(GO:0030426)
0.0 9.1 GO:0030054 cell junction(GO:0030054)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.5 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
3.0 38.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
2.6 10.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
2.1 10.6 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
2.1 14.6 GO:0097109 neuroligin family protein binding(GO:0097109)
1.6 7.8 GO:0008502 melatonin receptor activity(GO:0008502)
1.1 12.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.0 10.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.9 8.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.9 2.6 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.8 8.4 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.8 2.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.8 35.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.8 4.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.7 9.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.7 9.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.7 4.7 GO:0045340 mercury ion binding(GO:0045340)
0.6 1.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.5 11.1 GO:0000146 microfilament motor activity(GO:0000146)
0.5 9.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.5 13.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 5.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 3.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.3 2.2 GO:1901612 cardiolipin binding(GO:1901612)
0.3 0.8 GO:0031770 growth hormone-releasing hormone receptor binding(GO:0031770)
0.3 7.2 GO:0031402 sodium ion binding(GO:0031402)
0.2 4.3 GO:0043422 protein kinase B binding(GO:0043422)
0.2 6.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 6.2 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 9.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 4.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 10.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 5.1 GO:0030507 spectrin binding(GO:0030507)
0.1 3.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 15.3 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 2.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 5.8 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 25.1 GO:0045296 cadherin binding(GO:0045296)
0.1 4.0 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 5.7 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 6.8 GO:0030165 PDZ domain binding(GO:0030165)
0.1 5.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 11.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 1.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 25.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 3.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 2.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 6.9 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 2.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 11.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 10.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 10.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 10.3 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 4.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 5.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.7 PID TNF PATHWAY TNF receptor signaling pathway
0.1 2.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 4.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 9.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 10.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.7 9.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.6 32.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.4 6.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.4 7.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.3 12.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.3 4.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 10.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 2.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 5.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 3.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 1.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 9.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 8.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 4.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 10.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation