ISMARA results: Sox2

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Sox2

Z-value: 1.57

Motif logo

Transcription factors associated with Sox2

Gene Symbol	Gene ID	Gene Info
Sox2 NCBI RGD Ensembl	ENSRNOG00000012199	SRY box 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Sox2	rn6_v1_chr2_+_121165137_121165137	0.30	3.0e-08	Click!

Activity profile of Sox2 motif

Sorted Z-values of Sox2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_+_45289741 Show fit	44.84	ENSRNOT00000066190	Hist3h2ba NCBI RGD Ensembl Show fit	histone cluster 3, H2ba
chr5_+_64326733 Show fit	36.24	ENSRNOT00000065775	Tmeff1 NCBI RGD Ensembl Show fit	transmembrane protein with EGF-like and two follistatin-like domains 1
chr5_-_48165317 Show fit	35.28	ENSRNOT00000088179	Ankrd6 NCBI RGD Ensembl Show fit	ankyrin repeat domain 6
chr9_-_61810417 Show fit	32.01	ENSRNOT00000020910	Rftn2 NCBI RGD Ensembl Show fit	raftlin family member 2
chr18_+_79406381 Show fit	28.40	ENSRNOT00000022303 ENSRNOT00000058295 ENSRNOT00000058296 ENSRNOT00000022280	Mbp NCBI RGD Ensembl Show fit	myelin basic protein
chr17_+_9679628 Show fit	28.18	ENSRNOT00000019569 ENSRNOT00000019393	Dbn1 NCBI RGD Ensembl Show fit	drebrin 1
chr18_+_30562178 Show fit	26.96	ENSRNOT00000040998	LOC108348771 NCBI RGD Ensembl Show fit	protocadherin beta-16-like
chr16_+_22250470 Show fit	24.68	ENSRNOT00000015799	Lzts1 NCBI RGD Ensembl Show fit	leucine zipper tumor suppressor 1
chr5_+_152681101 Show fit	24.31	ENSRNOT00000076052 ENSRNOT00000022574	Stmn1 NCBI RGD Ensembl Show fit	stathmin 1
chr11_+_86512797 Show fit	24.30	ENSRNOT00000051680	Gp1bb NCBI RGD Ensembl Show fit	glycoprotein Ib platelet beta subunit
chr8_+_128824508 Show fit	23.68	ENSRNOT00000025343	Mobp NCBI RGD Ensembl Show fit	myelin-associated oligodendrocyte basic protein
chr6_-_147172022 Show fit	22.45	ENSRNOT00000080675	Itgb8 NCBI RGD Ensembl Show fit	integrin subunit beta 8
chr1_+_101214593 Show fit	21.46	ENSRNOT00000028086	Tead2 NCBI RGD Ensembl Show fit	TEA domain transcription factor 2
chr1_+_142679345 Show fit	21.37	ENSRNOT00000034267	Zscan2 NCBI RGD Ensembl Show fit	zinc finger and SCAN domain containing 2
chr18_-_26211445 Show fit	21.32	ENSRNOT00000027739	Nrep NCBI RGD Ensembl Show fit	neuronal regeneration related protein
chr13_-_95250235 Show fit	21.18	ENSRNOT00000085648	Akt3 NCBI RGD Ensembl Show fit	AKT serine/threonine kinase 3
chr16_-_39476025 Show fit	21.13	ENSRNOT00000014312	Gpm6a NCBI RGD Ensembl Show fit	glycoprotein m6a
chr8_+_60709851 Show fit	20.98	ENSRNOT00000021817	Rcn2 NCBI RGD Ensembl Show fit	reticulocalbin 2
chr12_+_28381982 Show fit	20.79	ENSRNOT00000076101	Wbscr17 NCBI RGD Ensembl Show fit	Williams-Beuren syndrome chromosome region 17
chr14_+_77380262 Show fit	20.65	ENSRNOT00000008030	Nsg1 NCBI RGD Ensembl Show fit	neuron specific gene family member 1
chr20_+_42966140 Show fit	20.50	ENSRNOT00000000707	Marcks NCBI RGD Ensembl Show fit	myristoylated alanine rich protein kinase C substrate
chr1_+_40816107 Show fit	20.43	ENSRNOT00000060767	Akap12 NCBI RGD Ensembl Show fit	A-kinase anchoring protein 12
chrX_+_105134498 Show fit	19.94	ENSRNOT00000002058	Tmem35 NCBI RGD Ensembl Show fit	transmembrane protein 35
chrX_-_115175299 Show fit	19.88	ENSRNOT00000074322	Dcx NCBI RGD Ensembl Show fit	doublecortin
chr2_-_57935334 Show fit	19.71	ENSRNOT00000022319 ENSRNOT00000085599 ENSRNOT00000077790 ENSRNOT00000035821	Slc1a3 NCBI RGD Ensembl Show fit	solute carrier family 1 member 3
chr5_+_127404450 Show fit	19.20	ENSRNOT00000017575	Lrp8 NCBI RGD Ensembl Show fit	LDL receptor related protein 8
chr1_+_264059374 Show fit	19.02	ENSRNOT00000075397	Scd2 NCBI RGD Ensembl Show fit	stearoyl-Coenzyme A desaturase 2
chr4_-_64330996 Show fit	18.92	ENSRNOT00000016088	Ptn NCBI RGD Ensembl Show fit	pleiotrophin
chr20_+_44521279 Show fit	18.83	ENSRNOT00000085987	Fyn NCBI RGD Ensembl Show fit	FYN proto-oncogene, Src family tyrosine kinase
chr14_+_71542057 Show fit	18.71	ENSRNOT00000082592 ENSRNOT00000083701 ENSRNOT00000084322	Prom1 NCBI RGD Ensembl Show fit	prominin 1
chr10_-_94352880 Show fit	18.35	ENSRNOT00000035973	Limd2 NCBI RGD Ensembl Show fit	LIM domain containing 2
chr1_-_48825364 Show fit	18.30	ENSRNOT00000024213	Agpat4 NCBI RGD Ensembl Show fit	1-acylglycerol-3-phosphate O-acyltransferase 4
chr17_+_47721977 Show fit	18.25	ENSRNOT00000080800	LOC100910792 NCBI RGD Ensembl Show fit	amphiphysin-like
chr1_+_78800754 Show fit	18.07	ENSRNOT00000084601	Dact3 NCBI RGD Ensembl Show fit	dishevelled-binding antagonist of beta-catenin 3
chr1_+_72860218 Show fit	17.92	ENSRNOT00000024547	Syt5 NCBI RGD Ensembl Show fit	synaptotagmin 5
chr1_-_146556171 Show fit	17.66	ENSRNOT00000017636	Arnt2 NCBI RGD Ensembl Show fit	aryl hydrocarbon receptor nuclear translocator 2
chr12_+_27155587 Show fit	17.37	ENSRNOT00000044800	AABR07035916.1 NCBI RGD Ensembl Show fit
chr2_-_29768750 Show fit	17.29	ENSRNOT00000023460	Map1b NCBI RGD Ensembl Show fit	microtubule-associated protein 1B
chr18_+_30435119 Show fit	17.29	ENSRNOT00000027190	Pcdhb8 NCBI RGD Ensembl Show fit	protocadherin beta 8
chr2_-_18531210 Show fit	17.23	ENSRNOT00000088313	Vcan NCBI RGD Ensembl Show fit	versican
chr5_+_152680407 Show fit	17.08	ENSRNOT00000076864	Stmn1 NCBI RGD Ensembl Show fit	stathmin 1
chr5_+_49311030 Show fit	17.04	ENSRNOT00000010850	Cnr1 NCBI RGD Ensembl Show fit	cannabinoid receptor 1
chr3_+_35014538 Show fit	16.77	ENSRNOT00000006341	Kif5c NCBI RGD Ensembl Show fit	kinesin family member 5C
chr5_+_147714163 Show fit	16.74	ENSRNOT00000012663	Marcksl1 NCBI RGD Ensembl Show fit	MARCKS-like 1
chr7_-_12275609 Show fit	16.74	ENSRNOT00000086061	Apc2 NCBI RGD Ensembl Show fit	APC2, WNT signaling pathway regulator
chr6_-_147172813 Show fit	16.60	ENSRNOT00000066545	Itgb8 NCBI RGD Ensembl Show fit	integrin subunit beta 8
chr10_-_4644570 Show fit	16.40	ENSRNOT00000088279	Snn NCBI RGD Ensembl Show fit	stannin
chr19_+_56220755 Show fit	16.27	ENSRNOT00000023452	Tubb3 NCBI RGD Ensembl Show fit	tubulin, beta 3 class III
chr8_-_62987182 Show fit	16.13	ENSRNOT00000070885	Islr2 NCBI RGD Ensembl Show fit	immunoglobulin superfamily containing leucine-rich repeat 2
chr6_+_44009872 Show fit	16.12	ENSRNOT00000082657	Mboat2 NCBI RGD Ensembl Show fit	membrane bound O-acyltransferase domain containing 2
chr14_-_78308933 Show fit	16.11	ENSRNOT00000065334	Crmp1 NCBI RGD Ensembl Show fit	collapsin response mediator protein 1
chr9_-_100253609 Show fit	15.93	ENSRNOT00000036061	Kif1a NCBI RGD Ensembl Show fit	kinesin family member 1A
chr10_-_56167426 Show fit	15.90	ENSRNOT00000013955	Efnb3 NCBI RGD Ensembl Show fit	ephrin B3
chr12_+_48316143 Show fit	15.90	ENSRNOT00000084511	Svop NCBI RGD Ensembl Show fit	SV2 related protein
chr12_+_25173005 Show fit	15.81	ENSRNOT00000033200 ENSRNOT00000091328	Clip2 NCBI RGD Ensembl Show fit	CAP-GLY domain containing linker protein 2
chr1_-_47213749 Show fit	15.73	ENSRNOT00000024656	Dynlt1 NCBI RGD Ensembl Show fit	dynein light chain Tctex-type 1
chr19_+_22450030 Show fit	15.69	ENSRNOT00000021739	Neto2 NCBI RGD Ensembl Show fit	neuropilin and tolloid like 2
chr3_+_161121697 Show fit	15.64	ENSRNOT00000036020	Wfdc10a NCBI RGD Ensembl Show fit	WAP four-disulfide core domain 10A
chr20_+_46199981 Show fit	15.48	ENSRNOT00000000337	Mical1 NCBI RGD Ensembl Show fit	microtubule associated monooxygenase, calponin and LIM domain containing 1
chr13_-_107831014 Show fit	15.42	ENSRNOT00000003684	Kcnk2 NCBI RGD Ensembl Show fit	potassium two pore domain channel subfamily K member 2
chr3_-_168018410 Show fit	15.29	ENSRNOT00000087579	Bcas1 NCBI RGD Ensembl Show fit	breast carcinoma amplified sequence 1
chr4_-_119131202 Show fit	15.03	ENSRNOT00000011675	Antxr1 NCBI RGD Ensembl Show fit	anthrax toxin receptor 1
chr4_+_29535852 Show fit	14.94	ENSRNOT00000087619	NEWGENE_621351 NCBI RGD Ensembl Show fit	collagen, type I, alpha 2
chr7_+_110031696 Show fit	14.93	ENSRNOT00000012753	Khdrbs3 NCBI RGD Ensembl Show fit	KH RNA binding domain containing, signal transduction associated 3
chrX_+_28593405 Show fit	14.92	ENSRNOT00000071708	Tmsb4x NCBI RGD Ensembl Show fit	thymosin beta 4, X-linked
chr13_-_72063347 Show fit	14.91	ENSRNOT00000090544 ENSRNOT00000003869	Cacna1e NCBI RGD Ensembl Show fit	calcium voltage-gated channel subunit alpha1 E
chr9_-_17866927 Show fit	14.89	ENSRNOT00000027031	Tcte1 NCBI RGD Ensembl Show fit	t-complex-associated testis expressed 1
chr10_-_107386072 Show fit	14.85	ENSRNOT00000004290	Timp2 NCBI RGD Ensembl Show fit	TIMP metallopeptidase inhibitor 2
chr6_+_132510757 Show fit	14.79	ENSRNOT00000080230	Evl NCBI RGD Ensembl Show fit	Enah/Vasp-like
chr18_+_15467870 Show fit	14.76	ENSRNOT00000091696	B4galt6 NCBI RGD Ensembl Show fit	beta-1,4-galactosyltransferase 6
chr8_-_39460844 Show fit	14.60	ENSRNOT00000048875	Pknox2 NCBI RGD Ensembl Show fit	PBX/knotted 1 homeobox 2
chr11_+_73738433 Show fit	14.56	ENSRNOT00000002353	Tmem44 NCBI RGD Ensembl Show fit	transmembrane protein 44
chr4_-_108008484 Show fit	14.43	ENSRNOT00000007971	Ctnna2 NCBI RGD Ensembl Show fit	catenin alpha 2
chr19_-_9801942 Show fit	14.37	ENSRNOT00000051414 ENSRNOT00000017494	Ndrg4 NCBI RGD Ensembl Show fit	NDRG family member 4
chr3_+_131351587 Show fit	14.36	ENSRNOT00000010835	Btbd3 NCBI RGD Ensembl Show fit	BTB domain containing 3
chr7_-_136853957 Show fit	14.24	ENSRNOT00000008985	Nell2 NCBI RGD Ensembl Show fit	neural EGFL like 2
chr3_-_3747440 Show fit	14.06	ENSRNOT00000036178	Ccdc187 NCBI RGD Ensembl Show fit	coiled-coil domain containing 187
chr10_+_31146107 Show fit	13.82	ENSRNOT00000008184	Adam19 NCBI RGD Ensembl Show fit	ADAM metallopeptidase domain 19
chr7_-_144837583 Show fit	13.77	ENSRNOT00000055289	Cbx5 NCBI RGD Ensembl Show fit	chromobox 5
chrX_+_62727755 Show fit	13.67	ENSRNOT00000077055	Pcyt1b NCBI RGD Ensembl Show fit	phosphate cytidylyltransferase 1, choline, beta
chr7_-_64251110 Show fit	13.67	ENSRNOT00000006180	Srgap1 NCBI RGD Ensembl Show fit	SLIT-ROBO Rho GTPase activating protein 1
chr3_-_51643140 Show fit	13.59	ENSRNOT00000006646	Scn3a NCBI RGD Ensembl Show fit	sodium voltage-gated channel alpha subunit 3
chr2_-_88414012 Show fit	13.44	ENSRNOT00000014762	Lrrcc1 NCBI RGD Ensembl Show fit	leucine rich repeat and coiled-coil centrosomal protein 1
chr15_-_44411004 Show fit	13.40	ENSRNOT00000031163	Cdca2 NCBI RGD Ensembl Show fit	cell division cycle associated 2
chr1_+_100447998 Show fit	13.28	ENSRNOT00000026259	Lrrc4b NCBI RGD Ensembl Show fit	leucine rich repeat containing 4B
chr12_-_33016885 Show fit	13.28	ENSRNOT00000048474	Tmem132c NCBI RGD Ensembl Show fit	transmembrane protein 132C
chr4_+_160455986 Show fit	13.28	ENSRNOT00000087834	Tspan11 NCBI RGD Ensembl Show fit	tetraspanin 11
chr5_+_18901039 Show fit	13.27	ENSRNOT00000012066	Fam110b NCBI RGD Ensembl Show fit	family with sequence similarity 110, member B
chr8_-_30222036 Show fit	13.18	ENSRNOT00000035454	Ntm NCBI RGD Ensembl Show fit	neurotrimin
chr12_-_13668515 Show fit	13.08	ENSRNOT00000086847	Fscn1 NCBI RGD Ensembl Show fit	fascin actin-bundling protein 1
chr20_+_3553455 Show fit	12.94	ENSRNOT00000090080	Ddr1 NCBI RGD Ensembl Show fit	discoidin domain receptor tyrosine kinase 1
chr13_-_100405339 Show fit	12.83	ENSRNOT00000039974	Enah NCBI RGD Ensembl Show fit	enabled homolog (Drosophila)
chr3_+_139695028 Show fit	12.75	ENSRNOT00000089098	Slc24a3 NCBI RGD Ensembl Show fit	solute carrier family 24 member 3
chr18_+_27424328 Show fit	12.72	ENSRNOT00000033784	Kif20a NCBI RGD Ensembl Show fit	kinesin family member 20A
chr4_+_77623538 Show fit	12.63	ENSRNOT00000059263	Zfp956 NCBI RGD Ensembl Show fit	zinc finger protein 956
chr18_+_30574627 Show fit	12.54	ENSRNOT00000060484	Pcdhb19 NCBI RGD Ensembl Show fit	protocadherin beta 19
chr3_-_123849788 Show fit	12.49	ENSRNOT00000028869	Rnf24 NCBI RGD Ensembl Show fit	ring finger protein 24
chr12_-_21746236 Show fit	12.49	ENSRNOT00000001869	LOC102550456 NCBI RGD Ensembl Show fit	TSC22 domain family protein 4-like
chr2_-_23909016 Show fit	12.39	ENSRNOT00000084044	Scamp1 NCBI RGD Ensembl Show fit	secretory carrier membrane protein 1
chr18_+_53915807 Show fit	12.33	ENSRNOT00000026543	Adamts19 NCBI RGD Ensembl Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 19
chr2_-_139528162 Show fit	12.24	ENSRNOT00000014317	Slc7a11 NCBI RGD Ensembl Show fit	solute carrier family 7 member 11
chrX_-_123662350 Show fit	12.21	ENSRNOT00000092624	Sept6 NCBI RGD Ensembl Show fit	septin 6
chr5_-_1347921 Show fit	12.04	ENSRNOT00000007994	Gdap1 NCBI RGD Ensembl Show fit	ganglioside-induced differentiation-associated-protein 1
chr2_+_187893875 Show fit	12.04	ENSRNOT00000093014	Mex3a NCBI RGD Ensembl Show fit	mex-3 RNA binding family member A
chr1_-_190914610 Show fit	12.00	ENSRNOT00000023189	Cdr2 NCBI RGD Ensembl Show fit	cerebellar degeneration-related protein 2
chr9_+_2202511 Show fit	11.97	ENSRNOT00000017556	Satb1 NCBI RGD Ensembl Show fit	SATB homeobox 1
chrX_+_6791136 Show fit	11.96	ENSRNOT00000003984	LOC100909913 NCBI RGD Ensembl Show fit	norrin-like
chr1_+_277689729 Show fit	11.96	ENSRNOT00000051834	Vwa2 NCBI RGD Ensembl Show fit	von Willebrand factor A domain containing 2
chr20_+_3552929 Show fit	11.95	ENSRNOT00000083223	Ddr1 NCBI RGD Ensembl Show fit	discoidin domain receptor tyrosine kinase 1
chrX_-_63999622 Show fit	11.81	ENSRNOT00000090902	LOC103694487 NCBI RGD Ensembl Show fit	protein gar2-like
chr1_-_170404056 Show fit	11.70	ENSRNOT00000024402	Apbb1 NCBI RGD Ensembl Show fit	amyloid beta precursor protein binding family B member 1
chr5_+_62840360 Show fit	11.66	ENSRNOT00000088385	Col15a1 NCBI RGD Ensembl Show fit	collagen type XV alpha 1 chain
chr6_+_109710781 Show fit	11.57	ENSRNOT00000012895	Ttll5 NCBI RGD Ensembl Show fit	tubulin tyrosine ligase like 5
chr14_+_83560541 Show fit	11.57	ENSRNOT00000057738 ENSRNOT00000085228	Pik3ip1 NCBI RGD Ensembl Show fit	phosphoinositide-3-kinase interacting protein 1
chr2_-_223322585 Show fit	11.49	ENSRNOT00000015036	Ptbp2 NCBI RGD Ensembl Show fit	polypyrimidine tract binding protein 2
chr12_+_2534212 Show fit	11.43	ENSRNOT00000001399	Ctxn1 NCBI RGD Ensembl Show fit	cortexin 1
chr10_-_85974644 Show fit	11.41	ENSRNOT00000006098 ENSRNOT00000082974	Cacnb1 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit beta 1
chr2_+_188528979 Show fit	11.40	ENSRNOT00000087934	Thbs3 NCBI RGD Ensembl Show fit	thrombospondin 3
chr5_+_104362971 Show fit	11.37	ENSRNOT00000058520	Adamtsl1 NCBI RGD Ensembl Show fit	ADAMTS-like 1
chr6_-_39363367 Show fit	11.33	ENSRNOT00000088687 ENSRNOT00000065531	Fam84a NCBI RGD Ensembl Show fit	family with sequence similarity 84, member A
chr6_+_100337226 Show fit	11.32	ENSRNOT00000011220	Fut8 NCBI RGD Ensembl Show fit	fucosyltransferase 8
chr17_+_75190783 Show fit	11.22	ENSRNOT00000085840	AABR07028568.1 NCBI RGD Ensembl Show fit
chr17_-_15566332 Show fit	11.12	ENSRNOT00000093743	Ecm2 NCBI RGD Ensembl Show fit	extracellular matrix protein 2
chr8_-_66893083 Show fit	11.06	ENSRNOT00000037028 ENSRNOT00000091755	Kif23 NCBI RGD Ensembl Show fit	kinesin family member 23
chr9_+_9961021 Show fit	11.01	ENSRNOT00000075767	Tubb4a NCBI RGD Ensembl Show fit	tubulin, beta 4A class IVa
chr8_+_62925357 Show fit	10.98	ENSRNOT00000011074 ENSRNOT00000090588	Stra6 NCBI RGD Ensembl Show fit	stimulated by retinoic acid 6
chr18_+_30904498 Show fit	10.90	ENSRNOT00000026969	Pcdhga11 NCBI RGD Ensembl Show fit	protocadherin gamma subfamily A, 11
chr5_+_139468546 Show fit	10.90	ENSRNOT00000013193	Slfnl1 NCBI RGD Ensembl Show fit	schlafen-like 1
chr7_-_140640953 Show fit	10.88	ENSRNOT00000083156	Tuba1a NCBI RGD Ensembl Show fit	tubulin, alpha 1A
chr15_-_6587367 Show fit	10.81	ENSRNOT00000038449	Zfp385d NCBI RGD Ensembl Show fit	zinc finger protein 385D
chr7_-_116607674 Show fit	10.80	ENSRNOT00000076014	Ly6h NCBI RGD Ensembl Show fit	lymphocyte antigen 6 complex, locus H
chr3_-_124610267 Show fit	10.74	ENSRNOT00000028883	Rassf2 NCBI RGD Ensembl Show fit	Ras association domain family member 2
chr3_+_129599353 Show fit	10.69	ENSRNOT00000008734	Snap25 NCBI RGD Ensembl Show fit	synaptosomal-associated protein 25
chrX_-_134866210 Show fit	10.61	ENSRNOT00000005331	Apln NCBI RGD Ensembl Show fit	apelin
chr10_-_56511583 Show fit	10.60	ENSRNOT00000021402	LOC497940 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 2810408A11
chr9_+_46657922 Show fit	10.58	ENSRNOT00000019180	Map4k4 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_165641573 Show fit	10.54	ENSRNOT00000013987	Trim59 NCBI RGD Ensembl Show fit	tripartite motif-containing 59
chr7_-_70577147 Show fit	10.47	ENSRNOT00000008854	Mbd6 NCBI RGD Ensembl Show fit	methyl-CpG binding domain protein 6
chr18_-_55771730 Show fit	10.41	ENSRNOT00000026426	Smim3 NCBI RGD Ensembl Show fit	small integral membrane protein 3
chr18_+_30909490 Show fit	10.39	ENSRNOT00000026967	Pcdhgb8 NCBI RGD Ensembl Show fit	protocadherin gamma subfamily B, 8
chr1_+_78876205 Show fit	10.38	ENSRNOT00000022610	Pnmal2 NCBI RGD Ensembl Show fit	paraneoplastic Ma antigen family-like 2
chr13_-_113817995 Show fit	10.38	ENSRNOT00000057151	Cd46 NCBI RGD Ensembl Show fit	CD46 molecule
chr1_+_211582077 Show fit	10.31	ENSRNOT00000023619	Pwwp2b NCBI RGD Ensembl Show fit	PWWP domain containing 2B
chr10_-_15155412 Show fit	10.29	ENSRNOT00000026536	Haghl NCBI RGD Ensembl Show fit	hydroxyacylglutathione hydrolase-like
chr8_-_60830448 Show fit	10.24	ENSRNOT00000022419	Tspan3 NCBI RGD Ensembl Show fit	tetraspanin 3
chr12_-_12712742 Show fit	10.22	ENSRNOT00000034483	Rsph10b NCBI RGD Ensembl Show fit	radial spoke head 10 homolog B
chr4_-_83972540 Show fit	10.19	ENSRNOT00000036951	Tril NCBI RGD Ensembl Show fit	TLR4 interactor with leucine-rich repeats
chr3_+_153580861 Show fit	10.18	ENSRNOT00000080516 ENSRNOT00000012739	Src NCBI RGD Ensembl Show fit	SRC proto-oncogene, non-receptor tyrosine kinase
chr15_+_40665041 Show fit	10.11	ENSRNOT00000018300	Amer2 NCBI RGD Ensembl Show fit	APC membrane recruitment protein 2
chr18_-_16543992 Show fit	10.09	ENSRNOT00000036306	Slc39a6 NCBI RGD Ensembl Show fit	solute carrier family 39 member 6
chr4_-_11497531 Show fit	10.08	ENSRNOT00000078799	Magi2 NCBI RGD Ensembl Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_-_84106997 Show fit	10.05	ENSRNOT00000065501	Osbp2 NCBI RGD Ensembl Show fit	oxysterol binding protein 2
chr16_+_74752655 Show fit	9.99	ENSRNOT00000029266	Ckap2 NCBI RGD Ensembl Show fit	cytoskeleton associated protein 2
chr7_-_136853154 Show fit	9.99	ENSRNOT00000087376	Nell2 NCBI RGD Ensembl Show fit	neural EGFL like 2
chr10_+_62674561 Show fit	9.99	ENSRNOT00000019946 ENSRNOT00000056110	Ankrd13b NCBI RGD Ensembl Show fit	ankyrin repeat domain 13B
chr4_-_157304653 Show fit	9.98	ENSRNOT00000051613	Lrrc23 NCBI RGD Ensembl Show fit	leucine rich repeat containing 23
chr17_-_77687456 Show fit	9.96	ENSRNOT00000045765 ENSRNOT00000081645	Frmd4a NCBI RGD Ensembl Show fit	FERM domain containing 4A
chr2_+_220298245 Show fit	9.89	ENSRNOT00000022625	Plppr4 NCBI RGD Ensembl Show fit	phospholipid phosphatase related 4
chr3_-_46457201 Show fit	9.85	ENSRNOT00000010683	Ly75 NCBI RGD Ensembl Show fit	lymphocyte antigen 75
chr6_+_110624856 Show fit	9.82	ENSRNOT00000014017	Vash1 NCBI RGD Ensembl Show fit	vasohibin 1
chr6_-_94980004 Show fit	9.78	ENSRNOT00000006373	Rtn1 NCBI RGD Ensembl Show fit	reticulon 1
chr1_-_81881549 Show fit	9.76	ENSRNOT00000027497	Atp1a3 NCBI RGD Ensembl Show fit	ATPase Na+/K+ transporting subunit alpha 3
chr3_+_155160481 Show fit	9.74	ENSRNOT00000021133	Ppp1r16b NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory subunit 16B
chr10_-_56429748 Show fit	9.72	ENSRNOT00000020675 ENSRNOT00000092704	Spem1 NCBI RGD Ensembl Show fit	spermatid maturation 1
chr7_-_83670356 Show fit	9.72	ENSRNOT00000005584	Sybu NCBI RGD Ensembl Show fit	syntabulin
chr12_-_8156151 Show fit	9.71	ENSRNOT00000064721	Mtus2 NCBI RGD Ensembl Show fit	microtubule associated tumor suppressor candidate 2
chrX_-_68562301 Show fit	9.68	ENSRNOT00000076720	Ophn1 NCBI RGD Ensembl Show fit	oligophrenin 1
chr11_-_87017115 Show fit	9.68	ENSRNOT00000051037	Rtn4r NCBI RGD Ensembl Show fit	reticulon 4 receptor
chr7_+_141355994 Show fit	9.66	ENSRNOT00000081195	Smarcd1 NCBI RGD Ensembl Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr4_-_100883038 Show fit	9.65	ENSRNOT00000041880	LOC100364435 NCBI RGD Ensembl Show fit	thymosin, beta 10-like
chr3_-_10602672 Show fit	9.64	ENSRNOT00000011648	Ncs1 NCBI RGD Ensembl Show fit	neuronal calcium sensor 1
chr7_+_141702038 Show fit	9.64	ENSRNOT00000086577	Dip2b NCBI RGD Ensembl Show fit	disco-interacting protein 2 homolog B
chr4_+_44321883 Show fit	9.61	ENSRNOT00000091095	Tes NCBI RGD Ensembl Show fit	testin LIM domain protein
chr6_+_43884678 Show fit	9.58	ENSRNOT00000091551	Rrm2 NCBI RGD Ensembl Show fit	ribonucleotide reductase regulatory subunit M2
chr7_-_15852930 Show fit	9.56	ENSRNOT00000009270	LOC691422 NCBI RGD Ensembl Show fit	similar to zinc finger protein 101
chr8_+_23113048 Show fit	9.52	ENSRNOT00000029577	Cnn1 NCBI RGD Ensembl Show fit	calponin 1
chr7_+_140315368 Show fit	9.51	ENSRNOT00000081206	Cacnb3 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit beta 3
chr18_+_30900291 Show fit	9.50	ENSRNOT00000060461	Pcdhgb7 NCBI RGD Ensembl Show fit	protocadherin gamma subfamily B, 7
chr18_-_74485139 Show fit	9.49	ENSRNOT00000022598	Slc14a1 NCBI RGD Ensembl Show fit	solute carrier family 14 member 1
chrX_+_70563570 Show fit	9.49	ENSRNOT00000003772	Gdpd2 NCBI RGD Ensembl Show fit	glycerophosphodiester phosphodiesterase domain containing 2
chr11_+_32440237 Show fit	9.47	ENSRNOT00000040844	Kcne2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily E regulatory subunit 2
chr1_-_140262452 Show fit	9.45	ENSRNOT00000046849 ENSRNOT00000045165 ENSRNOT00000025536 ENSRNOT00000041839	Ntrk3 NCBI RGD Ensembl Show fit	neurotrophic receptor tyrosine kinase 3
chr13_-_86451002 Show fit	9.45	ENSRNOT00000043004 ENSRNOT00000027996	Pbx1 NCBI RGD Ensembl Show fit	PBX homeobox 1
chr18_+_29993361 Show fit	9.43	ENSRNOT00000075810	Pcdha4 NCBI RGD Ensembl Show fit	protocadherin alpha 4
chr20_+_3351303 Show fit	9.37	ENSRNOT00000080419 ENSRNOT00000001065 ENSRNOT00000086503	Atat1 NCBI RGD Ensembl Show fit	alpha tubulin acetyltransferase 1
chr18_+_30381322 Show fit	9.36	ENSRNOT00000027216	Pcdhb3 NCBI RGD Ensembl Show fit	protocadherin beta 3
chr6_+_147876557 Show fit	9.35	ENSRNOT00000080090	Tmem196 NCBI RGD Ensembl Show fit	transmembrane protein 196
chr9_+_20241062 Show fit	9.33	ENSRNOT00000071593	LOC100911585 NCBI RGD Ensembl Show fit	leucine-rich repeat-containing protein 23-like
chr2_-_96520137 Show fit	9.32	ENSRNOT00000066966	Zc2hc1a NCBI RGD Ensembl Show fit	zinc finger, C2HC-type containing 1A
chr1_-_228753422 Show fit	9.32	ENSRNOT00000028626	Dtx4 NCBI RGD Ensembl Show fit	deltex E3 ubiquitin ligase 4
chr3_+_176102351 Show fit	9.31	ENSRNOT00000013105	Col9a3 NCBI RGD Ensembl Show fit	collagen type IX alpha 3 chain
chr20_+_5049496 Show fit	9.28	ENSRNOT00000088251 ENSRNOT00000001118	Ddah2 NCBI RGD Ensembl Show fit	dimethylarginine dimethylaminohydrolase 2
chr11_+_42936028 Show fit	9.24	ENSRNOT00000074653	AABR07033887.1 NCBI RGD Ensembl Show fit
chr8_+_64440214 Show fit	9.22	ENSRNOT00000058339	Parp6 NCBI RGD Ensembl Show fit	poly (ADP-ribose) polymerase family, member 6
chr1_+_144831523 Show fit	9.22	ENSRNOT00000039748	Mex3b NCBI RGD Ensembl Show fit	mex-3 RNA binding family member B
chr14_-_72025137 Show fit	9.19	ENSRNOT00000080604	C1qtnf7 NCBI RGD Ensembl Show fit	C1q and tumor necrosis factor related protein 7
chr15_+_41448064 Show fit	9.15	ENSRNOT00000019551	Sacs NCBI RGD Ensembl Show fit	sacsin molecular chaperone
chr9_+_82741920 Show fit	9.14	ENSRNOT00000027337	Slc4a3 NCBI RGD Ensembl Show fit	solute carrier family 4 member 3
chr11_-_36533073 Show fit	9.13	ENSRNOT00000033486	Lca5l NCBI RGD Ensembl Show fit	LCA5L, lebercilin like
chr7_+_64672722 Show fit	9.11	ENSRNOT00000064448 ENSRNOT00000005539	Grip1 NCBI RGD Ensembl Show fit	glutamate receptor interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.5	31.5	GO:0010643	cell communication by chemical coupling(GO:0010643)
10.1	30.4	GO:1904685	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) positive regulation of metalloendopeptidase activity(GO:1904685)
6.2	24.8	GO:1904616	regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
6.2	24.7	GO:0072139	glomerular parietal epithelial cell differentiation(GO:0072139)
5.9	23.6	GO:0070495	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
5.7	17.0	GO:0099552	trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
5.5	27.3	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
5.2	15.5	GO:0019417	sulfur oxidation(GO:0019417)
5.1	15.4	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
5.0	35.3	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
4.8	28.7	GO:0033227	dsRNA transport(GO:0033227)
4.8	19.0	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
4.7	18.9	GO:1904373	retinal rod cell differentiation(GO:0060221) response to kainic acid(GO:1904373)
4.5	13.4	GO:0043382	positive regulation of memory T cell differentiation(GO:0043382)
4.5	13.4	GO:2000312	regulation of kainate selective glutamate receptor activity(GO:2000312)
4.2	16.8	GO:0098961	dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
4.0	11.9	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
3.9	15.7	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
3.9	11.6	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
3.8	3.8	GO:0034724	DNA replication-independent nucleosome organization(GO:0034724)
3.7	11.0	GO:0046865	isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
3.6	25.1	GO:1905049	negative regulation of metallopeptidase activity(GO:1905049)
3.6	10.7	GO:1990926	short-term synaptic potentiation(GO:1990926)
3.5	3.5	GO:0060857	establishment of glial blood-brain barrier(GO:0060857)
3.5	17.4	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
3.4	20.7	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
3.3	13.1	GO:0030035	microspike assembly(GO:0030035)
3.2	9.7	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
3.2	34.8	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
3.2	9.5	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
3.1	18.8	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
3.1	9.4	GO:0071929	alpha-tubulin acetylation(GO:0071929)
3.1	15.4	GO:1900620	acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
3.0	15.0	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
3.0	9.0	GO:0060082	eye blink reflex(GO:0060082)
2.9	20.5	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
2.8	11.3	GO:0046368	GDP-L-fucose metabolic process(GO:0046368)
2.7	8.2	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
2.7	10.6	GO:0043397	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
2.6	26.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
2.6	25.7	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
2.5	7.5	GO:0060697	positive regulation of phospholipid catabolic process(GO:0060697)
2.5	15.0	GO:1905050	positive regulation of metallopeptidase activity(GO:1905050)
2.5	9.8	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
2.4	19.5	GO:0090273	regulation of somatostatin secretion(GO:0090273)
2.4	7.3	GO:0060490	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
2.4	26.7	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
2.4	9.7	GO:0038109	Kit signaling pathway(GO:0038109)
2.4	9.5	GO:0048687	positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
2.4	7.1	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
2.3	7.0	GO:1902103	metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
2.3	9.2	GO:0072697	protein localization to cell cortex(GO:0072697)
2.3	20.5	GO:1904116	response to vasopressin(GO:1904116)
2.3	20.4	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
2.3	6.8	GO:0071454	cellular response to anoxia(GO:0071454) regulation of establishment of Sertoli cell barrier(GO:1904444)
2.3	6.8	GO:0060988	lipid tube assembly(GO:0060988)
2.3	9.0	GO:0044313	protein K6-linked deubiquitination(GO:0044313)
2.2	6.7	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
2.2	24.2	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
2.2	8.7	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
2.2	6.5	GO:0048014	Tie signaling pathway(GO:0048014)
2.2	39.1	GO:0001573	ganglioside metabolic process(GO:0001573)
2.2	4.3	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
2.1	10.3	GO:0061727	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
2.0	10.2	GO:0060282	positive regulation of oocyte development(GO:0060282)
2.0	18.3	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
1.9	5.8	GO:0051037	regulation of transcription involved in meiotic cell cycle(GO:0051037)
1.9	5.7	GO:0052572	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
1.9	7.5	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
1.9	5.6	GO:0018201	peptidyl-glycine modification(GO:0018201)
1.9	5.6	GO:0002572	pro-T cell differentiation(GO:0002572)
1.9	5.6	GO:2000078	positive regulation of type B pancreatic cell development(GO:2000078)
1.9	5.6	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.8	24.0	GO:0061162	establishment of monopolar cell polarity(GO:0061162)
1.8	14.6	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
1.8	5.4	GO:0003322	pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
1.8	8.9	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.8	15.9	GO:0016198	axon choice point recognition(GO:0016198)
1.7	5.2	GO:0046103	inosine biosynthetic process(GO:0046103)
1.7	3.5	GO:2000974	negative regulation of pro-B cell differentiation(GO:2000974)
1.7	5.2	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
1.7	36.4	GO:0021819	layer formation in cerebral cortex(GO:0021819)
1.7	6.9	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
1.7	20.6	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
1.7	8.3	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
1.7	3.3	GO:0035425	autocrine signaling(GO:0035425)
1.7	5.0	GO:0014908	myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
1.7	6.6	GO:0060354	negative regulation of cell adhesion molecule production(GO:0060354)
1.6	4.9	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
1.6	8.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
1.6	21.1	GO:0051013	microtubule severing(GO:0051013)
1.6	9.7	GO:0023041	neuronal signal transduction(GO:0023041)
1.6	12.9	GO:2001135	regulation of endocytic recycling(GO:2001135)
1.6	9.5	GO:0071918	urea transmembrane transport(GO:0071918)
1.6	15.8	GO:0036376	sodium ion export from cell(GO:0036376)
1.5	6.2	GO:0090234	regulation of kinetochore assembly(GO:0090234)
1.5	3.1	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
1.5	6.1	GO:0061084	negative regulation of protein refolding(GO:0061084)
1.5	7.4	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.5	10.4	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.4	4.3	GO:0046038	guanine salvage(GO:0006178) GMP catabolic process(GO:0046038) guanine biosynthetic process(GO:0046099)
1.4	11.6	GO:0018095	protein polyglutamylation(GO:0018095)
1.4	4.3	GO:0072156	distal tubule morphogenesis(GO:0072156)
1.4	7.2	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.4	4.3	GO:0018199	peptidyl-glutamine modification(GO:0018199)
1.4	20.0	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.4	4.3	GO:0048143	astrocyte activation(GO:0048143)
1.4	5.7	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
1.4	12.7	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
1.4	16.8	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.4	2.8	GO:0048105	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
1.4	5.5	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
1.4	9.7	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
1.4	2.7	GO:0042631	cellular response to water deprivation(GO:0042631)
1.3	5.3	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
1.3	5.3	GO:0051643	endoplasmic reticulum localization(GO:0051643)
1.3	5.3	GO:0021747	cochlear nucleus development(GO:0021747)
1.3	9.1	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
1.3	2.6	GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.3	5.2	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
1.3	3.9	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
1.3	7.7	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
1.3	6.3	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
1.2	3.7	GO:0072137	mitral valve formation(GO:0003192) condensed mesenchymal cell proliferation(GO:0072137)
1.2	8.7	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
1.2	3.7	GO:0072720	response to dithiothreitol(GO:0072720)
1.2	6.2	GO:0044691	tooth eruption(GO:0044691)
1.2	4.9	GO:0072658	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.2	4.9	GO:1904158	axonemal central apparatus assembly(GO:1904158)
1.2	3.7	GO:0032241	positive regulation of nucleobase-containing compound transport(GO:0032241)
1.2	7.3	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.2	4.9	GO:0051586	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
1.2	2.4	GO:1904528	positive regulation of microtubule binding(GO:1904528)
1.2	7.2	GO:1904674	positive regulation of somatic stem cell population maintenance(GO:1904674)
1.2	6.0	GO:0036438	maintenance of lens transparency(GO:0036438)
1.2	3.6	GO:0007290	spermatid nucleus elongation(GO:0007290)
1.2	3.6	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
1.2	42.6	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
1.2	8.3	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
1.2	8.2	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
1.2	3.5	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
1.2	7.0	GO:0050915	sensory perception of sour taste(GO:0050915)
1.2	8.1	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
1.1	2.3	GO:0045110	intermediate filament bundle assembly(GO:0045110)
1.1	11.4	GO:0060346	bone trabecula formation(GO:0060346)
1.1	6.8	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
1.1	4.6	GO:1902164	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
1.1	6.8	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
1.1	14.7	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
1.1	7.9	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
1.1	12.4	GO:0090527	actin filament reorganization(GO:0090527)
1.1	3.4	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
1.1	6.7	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
1.1	3.3	GO:0032915	positive regulation of transforming growth factor beta2 production(GO:0032915)
1.1	17.4	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
1.1	2.2	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
1.1	2.2	GO:0006344	maintenance of chromatin silencing(GO:0006344)
1.1	3.2	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
1.1	6.4	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
1.1	4.2	GO:1902969	mitotic DNA replication(GO:1902969)
1.1	8.5	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
1.1	4.2	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
1.1	16.9	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
1.0	2.1	GO:2000437	regulation of monocyte extravasation(GO:2000437)
1.0	14.4	GO:0000920	cell separation after cytokinesis(GO:0000920)
1.0	11.2	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.0	1.0	GO:0086048	membrane depolarization during bundle of His cell action potential(GO:0086048)
1.0	6.1	GO:0060723	regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
1.0	3.0	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160)
1.0	4.0	GO:0097401	synaptic vesicle lumen acidification(GO:0097401)
1.0	22.1	GO:0034453	microtubule anchoring(GO:0034453)
1.0	11.0	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.0	4.0	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) NMDA selective glutamate receptor signaling pathway(GO:0098989)
1.0	5.9	GO:0035865	cellular response to potassium ion(GO:0035865)
1.0	12.7	GO:0051764	actin crosslink formation(GO:0051764)
1.0	15.6	GO:0090083	regulation of inclusion body assembly(GO:0090083)
1.0	2.9	GO:0043974	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
1.0	2.9	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
1.0	40.8	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
1.0	6.7	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
1.0	1.9	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.9	15.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.9	19.6	GO:0070932	histone H3 deacetylation(GO:0070932)
0.9	3.7	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.9	6.3	GO:0000103	sulfate assimilation(GO:0000103)
0.9	2.7	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
0.9	4.5	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.9	3.6	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.9	5.3	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.9	8.0	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.9	1.8	GO:0060166	olfactory pit development(GO:0060166)
0.9	1.7	GO:0071503	response to heparin(GO:0071503)
0.9	8.7	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.9	6.1	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.9	9.5	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.9	46.7	GO:0036465	synaptic vesicle recycling(GO:0036465)
0.9	12.0	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.9	2.6	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.9	3.4	GO:1904009	cellular response to monosodium glutamate(GO:1904009)
0.9	23.0	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.8	11.9	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.8	3.4	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.8	8.5	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
0.8	1.7	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.8	2.5	GO:0000105	histidine biosynthetic process(GO:0000105)
0.8	12.4	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.8	2.5	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.8	9.0	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.8	3.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.8	2.4	GO:0042489	negative regulation of odontogenesis(GO:0042483) negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.8	2.4	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.8	2.4	GO:0032831	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.8	1.6	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.8	1.6	GO:0008063	Toll signaling pathway(GO:0008063)
0.8	31.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.8	2.3	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.8	3.1	GO:0048478	replication fork protection(GO:0048478)
0.8	9.3	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.8	2.3	GO:0009609	response to symbiotic bacterium(GO:0009609)
0.8	9.2	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.8	3.0	GO:0015870	acetylcholine transport(GO:0015870)
0.7	5.2	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.7	8.1	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.7	5.2	GO:0000012	single strand break repair(GO:0000012)
0.7	7.3	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.7	2.1	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.7	9.3	GO:0006527	arginine catabolic process(GO:0006527)
0.7	7.1	GO:0001842	neural fold formation(GO:0001842)
0.7	18.4	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.7	4.9	GO:0098535	de novo centriole assembly(GO:0098535)
0.7	10.5	GO:0001675	acrosome assembly(GO:0001675)
0.7	4.2	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.7	4.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.7	7.6	GO:0007258	JUN phosphorylation(GO:0007258)
0.7	4.9	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305)
0.7	28.4	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.7	21.4	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.7	5.5	GO:0032808	lacrimal gland development(GO:0032808)
0.7	4.1	GO:0006449	regulation of translational termination(GO:0006449)
0.7	10.9	GO:0090382	phagosome maturation(GO:0090382)
0.7	8.1	GO:0005513	detection of calcium ion(GO:0005513)
0.7	2.0	GO:0021898	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.7	4.0	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.7	4.6	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.6	18.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.6	7.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.6	1.9	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.6	6.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.6	2.5	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.6	6.9	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.6	9.4	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.6	4.3	GO:1903817	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.6	4.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.6	29.8	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.6	1.8	GO:0070425	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.6	1.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.6	8.3	GO:0080111	DNA demethylation(GO:0080111)
0.6	1.2	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.6	4.1	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.6	5.3	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.6	1.8	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.6	80.7	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.6	4.1	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.6	2.9	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.6	7.5	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.6	9.7	GO:0035404	histone-serine phosphorylation(GO:0035404)
0.6	2.3	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.6	5.1	GO:0021860	pyramidal neuron development(GO:0021860)
0.6	1.1	GO:0071282	cellular response to iron(II) ion(GO:0071282)
0.6	2.8	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.6	1.1	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.6	1.7	GO:0097026	dendritic cell dendrite assembly(GO:0097026)
0.6	5.6	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.6	1.7	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.6	12.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.5	5.5	GO:0033623	regulation of integrin activation(GO:0033623)
0.5	13.4	GO:0095500	acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.5	4.8	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.5	26.0	GO:0031103	axon regeneration(GO:0031103)
0.5	1.6	GO:0019541	propionate metabolic process(GO:0019541)
0.5	46.2	GO:0006334	nucleosome assembly(GO:0006334)
0.5	4.7	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.5	5.2	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.5	3.1	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.5	1.5	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.5	2.5	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.5	4.5	GO:0044789	negative regulation of DNA endoreduplication(GO:0032876) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.5	12.5	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.5	1.9	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.5	7.2	GO:0097435	fibril organization(GO:0097435)
0.5	8.2	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.5	15.3	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.5	3.8	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.5	14.7	GO:0015701	bicarbonate transport(GO:0015701)
0.5	4.7	GO:0002467	germinal center formation(GO:0002467)
0.5	12.8	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.5	1.9	GO:0048194	Golgi vesicle budding(GO:0048194)
0.5	2.3	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.5	23.8	GO:0070527	platelet aggregation(GO:0070527)
0.5	6.1	GO:0019985	translesion synthesis(GO:0019985)
0.5	8.4	GO:0097503	sialylation(GO:0097503)
0.5	5.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.5	13.8	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.5	6.0	GO:0032274	gonadotropin secretion(GO:0032274)
0.5	1.4	GO:0032978	protein insertion into membrane from inner side(GO:0032978)
0.5	11.4	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.4	2.2	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.4	0.9	GO:0009957	epidermal cell fate specification(GO:0009957)
0.4	3.5	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4	5.7	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.4	4.8	GO:0060134	prepulse inhibition(GO:0060134)
0.4	0.8	GO:0032849	regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849)
0.4	4.6	GO:0070831	basement membrane assembly(GO:0070831)
0.4	2.9	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.4	7.0	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.4	5.4	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.4	5.3	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.4	24.3	GO:0043967	histone H4 acetylation(GO:0043967)
0.4	11.7	GO:0035307	positive regulation of protein dephosphorylation(GO:0035307)
0.4	13.7	GO:0019228	neuronal action potential(GO:0019228)
0.4	0.8	GO:1902263	cellular process regulating host cell cycle in response to virus(GO:0060154) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.4	3.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.4	1.6	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.4	5.1	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313)
0.4	4.3	GO:0070307	lens fiber cell development(GO:0070307)
0.4	3.5	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.4	10.5	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.4	5.0	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.4	6.9	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.4	1.1	GO:0060279	positive regulation of ovulation(GO:0060279)
0.4	1.9	GO:0043486	histone exchange(GO:0043486)
0.4	7.1	GO:0034142	toll-like receptor 4 signaling pathway(GO:0034142)
0.4	7.5	GO:0031572	mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.4	4.5	GO:0051451	myoblast migration(GO:0051451)
0.4	4.1	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.4	3.0	GO:0051382	kinetochore assembly(GO:0051382)
0.4	4.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.4	3.3	GO:0043584	nose development(GO:0043584)
0.4	1.1	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.4	1.8	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.4	0.7	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.4	20.9	GO:0030317	sperm motility(GO:0030317)
0.4	4.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.4	13.7	GO:0043966	histone H3 acetylation(GO:0043966)
0.4	3.9	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.4	3.2	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.4	6.0	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.4	2.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.4	1.8	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4	2.8	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.3	2.1	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.3	4.1	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090)
0.3	20.8	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.3	0.7	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.3	7.3	GO:1904037	positive regulation of epithelial cell apoptotic process(GO:1904037)
0.3	6.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.3	6.0	GO:0006298	mismatch repair(GO:0006298)
0.3	1.3	GO:0014842	regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.3	1.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.3	5.2	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.3	3.3	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.3	24.7	GO:0014020	primary neural tube formation(GO:0014020)
0.3	1.6	GO:1904424	regulation of GTP binding(GO:1904424)
0.3	5.3	GO:0010771	negative regulation of cell morphogenesis involved in differentiation(GO:0010771)
0.3	5.6	GO:0002092	positive regulation of receptor internalization(GO:0002092)
0.3	7.5	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.3	0.6	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
0.3	0.6	GO:0051866	general adaptation syndrome(GO:0051866)
0.3	1.2	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.3	3.0	GO:0035855	megakaryocyte development(GO:0035855)
0.3	2.4	GO:0070914	UV-damage excision repair(GO:0070914)
0.3	8.7	GO:0051310	metaphase plate congression(GO:0051310)
0.3	5.9	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.3	5.6	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.3	1.5	GO:0006337	nucleosome disassembly(GO:0006337)
0.3	3.2	GO:0019321	pentose metabolic process(GO:0019321)
0.3	5.3	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.3	3.7	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.3	13.6	GO:0051865	protein autoubiquitination(GO:0051865)
0.3	3.0	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.3	1.9	GO:0044030	regulation of DNA methylation(GO:0044030)
0.3	0.8	GO:1901367	response to L-cysteine(GO:1901367)
0.3	1.6	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.3	3.3	GO:0032620	interleukin-17 production(GO:0032620)
0.3	1.6	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.3	1.6	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.3	1.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.3	2.9	GO:0006895	Golgi to endosome transport(GO:0006895)
0.3	1.6	GO:0001927	exocyst assembly(GO:0001927)
0.3	5.2	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.3	1.0	GO:0031179	peptide modification(GO:0031179)
0.3	0.3	GO:0034971	histone H3-R17 methylation(GO:0034971)
0.3	2.0	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3	1.3	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3	2.8	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.3	4.0	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.2	5.7	GO:0030261	chromosome condensation(GO:0030261)
0.2	4.0	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.2	1.5	GO:2000819	regulation of nucleotide-excision repair(GO:2000819)
0.2	1.7	GO:0030259	lipid glycosylation(GO:0030259)
0.2	4.1	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.2	7.8	GO:0034605	cellular response to heat(GO:0034605)
0.2	1.7	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.2	12.2	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.2	4.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.2	2.4	GO:0036010	protein localization to endosome(GO:0036010)
0.2	11.9	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.2	9.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.2	16.1	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.2	8.4	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2	1.4	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2	0.9	GO:0031053	primary miRNA processing(GO:0031053)
0.2	1.5	GO:0015808	L-alanine transport(GO:0015808)
0.2	13.2	GO:0010977	negative regulation of neuron projection development(GO:0010977)
0.2	2.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.2	5.7	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.2	1.3	GO:0000212	meiotic spindle organization(GO:0000212)
0.2	2.5	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.2	0.4	GO:0045990	carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite regulation of transcription(GO:0045990) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016)
0.2	1.4	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.2	2.5	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.2	6.1	GO:0035987	endodermal cell differentiation(GO:0035987)
0.2	2.4	GO:0001502	cartilage condensation(GO:0001502)
0.2	1.0	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.2	2.1	GO:0007141	male meiosis I(GO:0007141)
0.2	2.7	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2	2.7	GO:0017121	phospholipid scrambling(GO:0017121)
0.2	1.9	GO:0048266	behavioral response to pain(GO:0048266)
0.2	13.0	GO:0048015	phosphatidylinositol-mediated signaling(GO:0048015)
0.2	1.5	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.2	4.7	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.2	5.4	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.2	3.0	GO:0001881	receptor recycling(GO:0001881)
0.2	1.8	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.2	12.5	GO:0048813	dendrite morphogenesis(GO:0048813)
0.2	2.4	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2	1.4	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2	1.1	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.2	0.3	GO:0071461	cellular response to redox state(GO:0071461)
0.2	2.7	GO:0097352	autophagosome maturation(GO:0097352)
0.2	4.6	GO:0050770	regulation of axonogenesis(GO:0050770)
0.2	66.7	GO:0007017	microtubule-based process(GO:0007017)
0.2	3.4	GO:0032720	negative regulation of tumor necrosis factor production(GO:0032720)
0.2	0.8	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.2	12.8	GO:0007286	spermatid development(GO:0007286)
0.2	3.2	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.2	12.8	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2	5.0	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.2	2.3	GO:0051058	negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.2	4.7	GO:1901216	positive regulation of neuron death(GO:1901216)
0.2	1.7	GO:0032674	regulation of interleukin-5 production(GO:0032674)
0.2	1.4	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
0.2	1.8	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.1	0.4	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.1	0.9	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	2.7	GO:0060325	face morphogenesis(GO:0060325)
0.1	1.0	GO:0071800	podosome assembly(GO:0071800)
0.1	3.2	GO:0018345	protein palmitoylation(GO:0018345)
0.1	4.6	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.1	1.9	GO:2000401	regulation of lymphocyte migration(GO:2000401)
0.1	1.0	GO:0032204	regulation of telomere maintenance(GO:0032204)
0.1	0.2	GO:0060017	parathyroid gland development(GO:0060017)
0.1	1.8	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1	1.6	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	5.3	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.1	1.6	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.1	0.4	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	4.2	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	1.2	GO:0033561	regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.1	1.6	GO:0006664	glycolipid metabolic process(GO:0006664)
0.1	1.9	GO:0034766	negative regulation of ion transmembrane transport(GO:0034766)
0.1	23.0	GO:0007283	spermatogenesis(GO:0007283)
0.1	0.5	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.1	2.1	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.1	0.5	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.1	1.4	GO:0009299	mRNA transcription(GO:0009299)
0.1	2.9	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.1	1.2	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	0.5	GO:0007340	acrosome reaction(GO:0007340)
0.1	2.1	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.1	1.5	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.1	1.9	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	2.2	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1	2.9	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.1	1.8	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.1	11.5	GO:0006813	potassium ion transport(GO:0006813)
0.1	2.5	GO:0021915	neural tube development(GO:0021915)
0.1	0.2	GO:0090367	regulation of mRNA modification(GO:0090365) negative regulation of mRNA modification(GO:0090367)
0.1	2.3	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1	0.8	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.1	1.2	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.1	0.4	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	1.2	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
0.1	2.0	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1	7.6	GO:0000398	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1	3.3	GO:0030183	B cell differentiation(GO:0030183)
0.1	1.6	GO:0042472	inner ear morphogenesis(GO:0042472)
0.1	2.8	GO:0007050	cell cycle arrest(GO:0007050)
0.1	0.7	GO:0016540	protein autoprocessing(GO:0016540)
0.0	5.1	GO:0008654	phospholipid biosynthetic process(GO:0008654)
0.0	2.5	GO:0010921	regulation of phosphatase activity(GO:0010921)
0.0	0.1	GO:0036102	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0	0.8	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.6	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0	0.9	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	1.3	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	3.9	GO:0006413	translational initiation(GO:0006413)
0.0	0.4	GO:0071731	response to nitric oxide(GO:0071731) cellular response to nitric oxide(GO:0071732)
0.0	1.1	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.5	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.0	0.5	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	8.3	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.0	2.5	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	1.5	GO:0006414	translational elongation(GO:0006414)
0.0	0.4	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.2	GO:0051497	negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.0	0.6	GO:0006400	tRNA modification(GO:0006400)
0.0	0.8	GO:0006275	regulation of DNA replication(GO:0006275)
0.0	0.5	GO:0001942	hair follicle development(GO:0001942) skin epidermis development(GO:0098773)
0.0	0.0	GO:0021859	pyramidal neuron differentiation(GO:0021859)
0.0	1.9	GO:0006887	exocytosis(GO:0006887)
0.0	0.5	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.2	GO:0050885	neuromuscular process controlling balance(GO:0050885)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.0	39.1	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
6.4	25.7	GO:0042585	germinal vesicle(GO:0042585)
6.2	37.2	GO:0033269	internode region of axon(GO:0033269)
4.7	28.2	GO:0044308	axonal spine(GO:0044308)
4.7	18.7	GO:0071914	prominosome(GO:0071914)
4.4	13.1	GO:0044393	microspike(GO:0044393)
4.2	12.5	GO:0071149	TEAD-2-YAP complex(GO:0071149)
4.1	20.7	GO:0098845	postsynaptic endosome(GO:0098845)
4.1	16.4	GO:0097149	centralspindlin complex(GO:0097149)
4.1	12.2	GO:0032173	septin collar(GO:0032173)
3.6	17.9	GO:1990769	proximal neuron projection(GO:1990769)
3.4	13.7	GO:0005593	FACIT collagen trimer(GO:0005593)
3.4	10.1	GO:0060187	cell pole(GO:0060187)
3.0	23.9	GO:0044305	calyx of Held(GO:0044305)
2.9	11.7	GO:1990812	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
2.9	28.9	GO:0097433	dense body(GO:0097433)
2.8	8.3	GO:0000811	GINS complex(GO:0000811)
2.6	10.4	GO:0002079	inner acrosomal membrane(GO:0002079)
2.4	9.8	GO:0044326	dendritic spine neck(GO:0044326)
2.4	9.6	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
2.3	9.4	GO:0097427	microtubule bundle(GO:0097427)
2.3	6.8	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
2.2	6.7	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
2.1	10.7	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
2.1	6.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
2.0	10.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
2.0	8.1	GO:0097451	glial limiting end-foot(GO:0097451)
1.9	7.8	GO:0034657	GID complex(GO:0034657)
1.8	30.5	GO:0031258	lamellipodium membrane(GO:0031258)
1.6	32.7	GO:0010369	chromocenter(GO:0010369)
1.6	11.4	GO:0036128	CatSper complex(GO:0036128)
1.5	40.0	GO:0005868	cytoplasmic dynein complex(GO:0005868)
1.4	7.0	GO:0097165	nuclear stress granule(GO:0097165)
1.4	5.6	GO:0031592	centrosomal corona(GO:0031592)
1.4	6.8	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
1.3	6.7	GO:0005883	neurofilament(GO:0005883)
1.3	5.2	GO:0098888	extrinsic component of presynaptic membrane(GO:0098888)
1.3	9.0	GO:0048787	presynaptic active zone membrane(GO:0048787)
1.3	3.8	GO:0098855	HCN channel complex(GO:0098855)
1.3	3.8	GO:0035101	FACT complex(GO:0035101)
1.3	11.3	GO:0005641	nuclear envelope lumen(GO:0005641)
1.2	7.5	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.2	1.2	GO:0031209	SCAR complex(GO:0031209)
1.2	18.1	GO:0071565	nBAF complex(GO:0071565)
1.2	14.4	GO:0005687	U4 snRNP(GO:0005687)
1.2	16.8	GO:0035253	ciliary rootlet(GO:0035253)
1.2	8.4	GO:0042382	paraspeckles(GO:0042382)
1.2	4.7	GO:0019815	B cell receptor complex(GO:0019815)
1.2	4.6	GO:0005607	laminin-2 complex(GO:0005607)
1.1	41.0	GO:0044295	axonal growth cone(GO:0044295)
1.1	22.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
1.1	5.6	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
1.1	5.4	GO:0071953	elastic fiber(GO:0071953)
1.1	33.4	GO:0035371	microtubule plus-end(GO:0035371)
1.0	8.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
1.0	10.1	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.0	12.6	GO:0000124	SAGA complex(GO:0000124)
1.0	17.2	GO:0001520	outer dense fiber(GO:0001520)
0.9	8.3	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.9	5.4	GO:1990752	microtubule end(GO:1990752)
0.9	6.3	GO:0032584	growth cone membrane(GO:0032584)
0.9	2.7	GO:0008537	proteasome activator complex(GO:0008537)
0.9	4.4	GO:0044530	supraspliceosomal complex(GO:0044530)
0.9	6.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.9	12.3	GO:0071437	invadopodium(GO:0071437)
0.9	5.3	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.9	9.6	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.9	5.2	GO:0005869	dynactin complex(GO:0005869)
0.9	8.7	GO:0008290	F-actin capping protein complex(GO:0008290)
0.9	17.3	GO:0043196	varicosity(GO:0043196)
0.8	4.2	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.8	6.7	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.8	6.5	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.8	4.0	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.8	2.4	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.8	3.2	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.8	9.5	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.8	2.4	GO:1990590	ATF1-ATF4 transcription factor complex(GO:1990590)
0.8	22.4	GO:0051233	spindle midzone(GO:0051233)
0.8	75.2	GO:0000786	nucleosome(GO:0000786)
0.8	2.3	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.8	16.7	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.8	31.8	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.8	10.6	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.7	19.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.7	12.4	GO:0042589	zymogen granule membrane(GO:0042589)
0.7	47.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.7	8.0	GO:0097449	astrocyte projection(GO:0097449)
0.7	1.4	GO:0044327	dendritic spine head(GO:0044327)
0.7	34.7	GO:0005720	nuclear heterochromatin(GO:0005720)
0.7	8.5	GO:0000812	Swr1 complex(GO:0000812)
0.7	19.0	GO:0005875	microtubule associated complex(GO:0005875)
0.7	9.6	GO:0031045	dense core granule(GO:0031045)
0.6	4.5	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.6	43.4	GO:0042734	presynaptic membrane(GO:0042734)
0.6	28.3	GO:0005871	kinesin complex(GO:0005871)
0.6	11.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.6	3.7	GO:0000137	Golgi cis cisterna(GO:0000137)
0.6	8.0	GO:0031143	pseudopodium(GO:0031143)
0.6	4.3	GO:0072687	meiotic spindle(GO:0072687)
0.6	19.6	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.6	1.8	GO:1990879	CST complex(GO:1990879)
0.6	7.9	GO:0035686	sperm fibrous sheath(GO:0035686)
0.6	6.0	GO:1990635	proximal dendrite(GO:1990635)
0.6	138.0	GO:0005874	microtubule(GO:0005874)
0.6	3.0	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.6	3.6	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.6	4.7	GO:0098645	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.6	4.6	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.6	2.2	GO:0070545	PeBoW complex(GO:0070545)
0.5	11.0	GO:0005922	connexon complex(GO:0005922)
0.5	9.7	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.5	6.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.5	13.7	GO:0030992	intraciliary transport particle B(GO:0030992)
0.5	0.5	GO:0032059	bleb(GO:0032059)
0.5	35.7	GO:0031901	early endosome membrane(GO:0031901)
0.5	16.6	GO:0031941	filamentous actin(GO:0031941)
0.5	33.3	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.5	21.8	GO:0045171	intercellular bridge(GO:0045171)
0.5	4.9	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.5	6.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.5	2.4	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.5	1.4	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5	8.0	GO:0036038	MKS complex(GO:0036038)
0.5	3.3	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.5	3.7	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.5	5.5	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5	1.8	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.4	13.5	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4	23.2	GO:0005581	collagen trimer(GO:0005581)
0.4	4.0	GO:0001891	phagocytic cup(GO:0001891)
0.4	12.6	GO:0002102	podosome(GO:0002102)
0.4	9.0	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.4	3.0	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.4	5.5	GO:0044666	MLL3/4 complex(GO:0044666)
0.4	4.7	GO:0016600	flotillin complex(GO:0016600)
0.4	4.2	GO:0034464	BBSome(GO:0034464)
0.4	10.1	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.4	3.8	GO:0000813	ESCRT I complex(GO:0000813)
0.4	10.9	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.4	1.7	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.4	2.9	GO:0005579	membrane attack complex(GO:0005579)
0.4	1.2	GO:0034774	secretory granule lumen(GO:0034774)
0.4	92.5	GO:0060076	excitatory synapse(GO:0060076)
0.4	10.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.4	33.8	GO:0043195	terminal bouton(GO:0043195)
0.4	5.1	GO:0005686	U2 snRNP(GO:0005686)
0.4	31.9	GO:0005604	basement membrane(GO:0005604)
0.4	5.4	GO:0097440	apical dendrite(GO:0097440)
0.4	9.7	GO:0046930	pore complex(GO:0046930)
0.4	7.4	GO:0005614	interstitial matrix(GO:0005614)
0.4	22.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4	5.8	GO:0042612	MHC class I protein complex(GO:0042612)
0.4	41.5	GO:0030027	lamellipodium(GO:0030027)
0.4	6.1	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3	5.9	GO:0002080	acrosomal membrane(GO:0002080)
0.3	3.7	GO:0005685	U1 snRNP(GO:0005685)
0.3	16.9	GO:0034707	chloride channel complex(GO:0034707)
0.3	1.0	GO:0034706	sodium channel complex(GO:0034706)
0.3	5.9	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.3	2.6	GO:0031616	spindle pole centrosome(GO:0031616)
0.3	1.9	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.3	1.5	GO:0031501	mannosyltransferase complex(GO:0031501)
0.3	0.9	GO:0061574	ASAP complex(GO:0061574)
0.3	101.2	GO:0005813	centrosome(GO:0005813)
0.3	5.2	GO:0071011	precatalytic spliceosome(GO:0071011)
0.3	25.4	GO:0031514	motile cilium(GO:0031514)
0.3	20.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.3	5.6	GO:0045120	pronucleus(GO:0045120)
0.3	11.2	GO:0045335	phagocytic vesicle(GO:0045335)
0.3	59.3	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.3	2.3	GO:0045178	basal part of cell(GO:0045178)
0.3	4.8	GO:0000145	exocyst(GO:0000145)
0.3	1.9	GO:0030914	STAGA complex(GO:0030914)
0.3	6.0	GO:0060170	ciliary membrane(GO:0060170)
0.3	0.8	GO:0005642	annulate lamellae(GO:0005642)
0.3	6.2	GO:0032420	stereocilium(GO:0032420)
0.3	2.7	GO:0017119	Golgi transport complex(GO:0017119)
0.3	2.6	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3	17.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.2	9.1	GO:0000779	condensed chromosome, centromeric region(GO:0000779)
0.2	7.3	GO:0000776	kinetochore(GO:0000776)
0.2	1.6	GO:0000815	ESCRT III complex(GO:0000815)
0.2	2.5	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.2	14.0	GO:0005811	lipid particle(GO:0005811)
0.2	20.4	GO:0005815	microtubule organizing center(GO:0005815)
0.2	172.2	GO:0005887	integral component of plasma membrane(GO:0005887)
0.2	1.6	GO:0031931	TORC1 complex(GO:0031931)
0.2	1.7	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.2	2.7	GO:0035145	exon-exon junction complex(GO:0035145)
0.2	1.5	GO:0005638	lamin filament(GO:0005638)
0.2	22.0	GO:0005681	spliceosomal complex(GO:0005681)
0.2	8.1	GO:0015030	Cajal body(GO:0015030)
0.2	4.2	GO:0032040	small-subunit processome(GO:0032040)
0.2	10.3	GO:0043204	perikaryon(GO:0043204)
0.2	22.0	GO:0043209	myelin sheath(GO:0043209)
0.2	2.9	GO:0042629	mast cell granule(GO:0042629)
0.2	3.9	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.2	3.0	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.2	1.2	GO:0034709	methylosome(GO:0034709)
0.2	4.5	GO:0016235	aggresome(GO:0016235)
0.1	3.3	GO:0035861	site of double-strand break(GO:0035861)
0.1	5.3	GO:0043596	nuclear replication fork(GO:0043596)
0.1	4.1	GO:0043197	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1	1.6	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.1	8.7	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	7.4	GO:0016363	nuclear matrix(GO:0016363)
0.1	0.6	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	6.8	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	8.3	GO:0031253	cell projection membrane(GO:0031253)
0.1	7.7	GO:0048475	membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1	2.1	GO:0043679	axon terminus(GO:0043679)
0.1	7.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	4.0	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	1.7	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.1	0.9	GO:1902555	endoribonuclease complex(GO:1902555)
0.1	1.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	8.5	GO:0005938	cell cortex(GO:0005938)
0.1	20.8	GO:0005925	focal adhesion(GO:0005925)
0.1	7.4	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1	12.3	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	4.9	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1	10.4	GO:0031012	extracellular matrix(GO:0031012)
0.1	0.3	GO:0032389	MutLalpha complex(GO:0032389)
0.1	0.3	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.1	0.9	GO:0005845	mRNA cap binding complex(GO:0005845)
0.1	12.9	GO:0016607	nuclear speck(GO:0016607)
0.1	40.4	GO:0005730	nucleolus(GO:0005730)
0.1	0.3	GO:0001772	immunological synapse(GO:0001772)
0.1	9.2	GO:0000790	nuclear chromatin(GO:0000790)
0.0	1.8	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.7	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.7	GO:0016592	mediator complex(GO:0016592)
0.0	0.5	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.3	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.7	45.7	GO:1990430	extracellular matrix protein binding(GO:1990430)
5.5	27.3	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
5.2	62.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
5.1	41.0	GO:0035374	chondroitin sulfate binding(GO:0035374)
4.8	19.3	GO:0042610	CD8 receptor binding(GO:0042610)
4.8	19.0	GO:0032896	stearoyl-CoA 9-desaturase activity(GO:0004768) palmitoyl-CoA 9-desaturase activity(GO:0032896)
4.6	32.4	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
4.3	25.8	GO:0032051	clathrin light chain binding(GO:0032051)
4.3	17.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
4.2	20.9	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
4.1	12.2	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
3.8	19.2	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
3.8	19.0	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
3.7	66.7	GO:0005522	profilin binding(GO:0005522)
3.7	14.8	GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
3.5	14.0	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
3.1	9.3	GO:0016403	dimethylargininase activity(GO:0016403)
3.1	15.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
3.1	15.4	GO:0022841	potassium ion leak channel activity(GO:0022841)
2.9	11.7	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
2.9	8.7	GO:0031762	follicle-stimulating hormone receptor binding(GO:0031762)
2.8	8.4	GO:0015489	polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
2.7	8.2	GO:0008481	sphinganine kinase activity(GO:0008481)
2.7	8.0	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
2.5	7.5	GO:0070976	TIR domain binding(GO:0070976)
2.5	7.4	GO:0031997	N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
2.5	14.8	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.4	14.6	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
2.4	9.6	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
2.4	7.2	GO:0001565	phorbol ester receptor activity(GO:0001565)
2.4	9.5	GO:0015265	urea channel activity(GO:0015265)
2.3	9.4	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
2.3	7.0	GO:0044736	acid-sensing ion channel activity(GO:0044736)
2.2	9.0	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
2.2	11.1	GO:0070052	collagen V binding(GO:0070052)
2.1	17.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
2.1	6.3	GO:0004020	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
2.1	26.8	GO:0070097	delta-catenin binding(GO:0070097)
2.1	6.2	GO:0033142	progesterone receptor binding(GO:0033142)
2.1	10.3	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
2.0	8.0	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.9	18.9	GO:0034190	apolipoprotein receptor binding(GO:0034190)
1.8	12.7	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
1.7	5.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
1.7	6.8	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
1.7	20.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
1.7	5.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
1.6	9.6	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
1.6	9.5	GO:0005030	neurotrophin receptor activity(GO:0005030)
1.6	6.3	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
1.6	6.3	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733)
1.5	18.4	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
1.5	16.8	GO:0042577	lipid phosphatase activity(GO:0042577)
1.5	10.5	GO:0045504	dynein heavy chain binding(GO:0045504)
1.5	6.0	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.5	5.9	GO:0035614	snRNA stem-loop binding(GO:0035614)
1.4	17.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
1.4	4.3	GO:0005113	patched binding(GO:0005113)
1.4	12.6	GO:0043515	kinetochore binding(GO:0043515)
1.4	11.0	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
1.4	4.1	GO:1990460	leptin receptor binding(GO:1990460)
1.4	4.1	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
1.3	9.4	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.3	15.7	GO:0003774	motor activity(GO:0003774)
1.3	23.5	GO:0031005	filamin binding(GO:0031005)
1.3	36.2	GO:0005540	hyaluronic acid binding(GO:0005540)
1.3	46.0	GO:0046875	ephrin receptor binding(GO:0046875)
1.2	8.6	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
1.2	20.9	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
1.2	7.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.2	8.3	GO:1904047	S-adenosyl-L-methionine binding(GO:1904047)
1.2	18.8	GO:0008179	adenylate cyclase binding(GO:0008179)
1.1	9.1	GO:0017070	U6 snRNA binding(GO:0017070) U4 snRNA binding(GO:0030621)
1.1	8.9	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.1	7.6	GO:0045505	dynein intermediate chain binding(GO:0045505)
1.1	59.2	GO:0005080	protein kinase C binding(GO:0005080)
1.1	9.6	GO:0045499	chemorepellent activity(GO:0045499)
1.1	9.5	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
1.0	18.6	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
1.0	8.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.0	3.1	GO:0004832	valine-tRNA ligase activity(GO:0004832)
1.0	4.8	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
1.0	13.4	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.9	8.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.9	14.9	GO:0035174	histone serine kinase activity(GO:0035174)
0.9	2.8	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.9	16.7	GO:0051010	microtubule plus-end binding(GO:0051010)
0.9	16.6	GO:0032794	GTPase activating protein binding(GO:0032794)
0.9	17.5	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.9	11.0	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.9	4.5	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.9	2.7	GO:0097677	STAT family protein binding(GO:0097677)
0.9	4.5	GO:0036033	mediator complex binding(GO:0036033)
0.9	6.1	GO:0004111	creatine kinase activity(GO:0004111)
0.9	223.4	GO:0008017	microtubule binding(GO:0008017)
0.9	2.6	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.8	3.4	GO:0001884	pyrimidine nucleoside binding(GO:0001884) deoxynucleoside kinase activity(GO:0019136)
0.8	13.2	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.8	11.5	GO:0005243	gap junction channel activity(GO:0005243)
0.8	11.4	GO:0050811	GABA receptor binding(GO:0050811)
0.8	7.9	GO:0003680	AT DNA binding(GO:0003680)
0.8	3.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.8	4.6	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.8	9.9	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.8	7.6	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.7	12.6	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.7	76.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.7	35.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.7	4.4	GO:0045503	dynein light chain binding(GO:0045503)
0.7	3.7	GO:0045322	unmethylated CpG binding(GO:0045322)
0.7	6.4	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.7	42.2	GO:0019003	GDP binding(GO:0019003)
0.7	10.4	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.7	2.7	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.7	2.7	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.7	10.1	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.7	5.4	GO:0070990	snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446)
0.7	5.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.7	9.9	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.6	5.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.6	2.5	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.6	7.5	GO:0008417	fucosyltransferase activity(GO:0008417)
0.6	11.8	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.6	8.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.6	3.7	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.6	10.4	GO:0001848	complement binding(GO:0001848)
0.6	6.6	GO:0005372	water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.6	12.4	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.6	3.5	GO:1990226	histone methyltransferase binding(GO:1990226)
0.6	8.1	GO:0051400	BH domain binding(GO:0051400)
0.6	5.8	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.6	2.9	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.6	8.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6	2.3	GO:1990254	keratin filament binding(GO:1990254)
0.6	2.8	GO:0005042	netrin receptor activity(GO:0005042)
0.6	11.2	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.5	8.2	GO:0048156	tau protein binding(GO:0048156)
0.5	46.2	GO:0015631	tubulin binding(GO:0015631)
0.5	3.3	GO:0050786	RAGE receptor binding(GO:0050786)
0.5	1.6	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.5	2.7	GO:0061133	endopeptidase activator activity(GO:0061133)
0.5	4.8	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.5	4.2	GO:0004565	beta-galactosidase activity(GO:0004565)
0.5	2.6	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.5	3.1	GO:0036310	annealing helicase activity(GO:0036310)
0.5	2.6	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.5	35.6	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.5	7.7	GO:0017049	GTP-Rho binding(GO:0017049)
0.5	2.5	GO:0089720	caspase binding(GO:0089720)
0.5	2.5	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5	22.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.5	9.5	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.5	3.0	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.5	6.0	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.5	4.9	GO:0001222	transcription corepressor binding(GO:0001222)
0.5	3.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.5	6.4	GO:0000400	four-way junction DNA binding(GO:0000400)
0.5	3.8	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.5	11.4	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.5	4.2	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.5	8.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.5	9.3	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.5	8.8	GO:0070628	proteasome binding(GO:0070628)
0.5	4.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.5	1.4	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.5	22.0	GO:0042805	actinin binding(GO:0042805)
0.5	10.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.4	11.6	GO:0017091	AU-rich element binding(GO:0017091)
0.4	4.4	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.4	1.8	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.4	20.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.4	2.2	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.4	16.5	GO:0048365	Rac GTPase binding(GO:0048365)
0.4	5.6	GO:0017154	semaphorin receptor activity(GO:0017154)
0.4	3.8	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.4	10.4	GO:0003785	actin monomer binding(GO:0003785)
0.4	2.1	GO:0001515	opioid peptide activity(GO:0001515)
0.4	2.9	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.4	8.5	GO:0017075	syntaxin-1 binding(GO:0017075)
0.4	2.4	GO:0019976	interleukin-2 binding(GO:0019976)
0.4	1.6	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.4	11.0	GO:0051183	vitamin transporter activity(GO:0051183)
0.4	7.8	GO:0004890	GABA-A receptor activity(GO:0004890)
0.4	5.7	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.4	4.1	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.4	8.1	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.4	2.9	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.4	8.7	GO:0070412	R-SMAD binding(GO:0070412)
0.4	5.0	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.4	7.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.3	2.8	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.3	2.7	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.3	3.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.3	4.9	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.3	1.6	GO:0004974	leukotriene receptor activity(GO:0004974)
0.3	5.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3	0.6	GO:0017166	vinculin binding(GO:0017166)
0.3	29.9	GO:0017124	SH3 domain binding(GO:0017124)
0.3	18.0	GO:0035064	methylated histone binding(GO:0035064)
0.3	1.5	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.3	1.8	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.3	2.4	GO:0070300	phosphatidic acid binding(GO:0070300)
0.3	0.9	GO:0005119	smoothened binding(GO:0005119)
0.3	3.3	GO:0019789	SUMO transferase activity(GO:0019789)
0.3	10.1	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.3	1.7	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.3	0.9	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.3	3.7	GO:0003688	DNA replication origin binding(GO:0003688)
0.3	1.7	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.3	0.8	GO:0003921	GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
0.3	2.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.3	5.8	GO:0005112	Notch binding(GO:0005112)
0.3	5.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.3	5.2	GO:0004622	lysophospholipase activity(GO:0004622)
0.3	0.8	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3	1.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.3	10.5	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.3	4.1	GO:0017160	Ral GTPase binding(GO:0017160)
0.3	7.3	GO:0015485	cholesterol binding(GO:0015485)
0.3	2.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	4.0	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2	2.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2	1.9	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2	2.7	GO:0042043	neurexin family protein binding(GO:0042043)
0.2	52.7	GO:0005096	GTPase activator activity(GO:0005096)
0.2	4.3	GO:0070402	NADPH binding(GO:0070402)
0.2	2.6	GO:0030955	potassium ion binding(GO:0030955)
0.2	3.0	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.2	5.7	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.2	2.7	GO:0008097	5S rRNA binding(GO:0008097)
0.2	4.7	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2	1.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.2	0.8	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2	1.5	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2	1.9	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.2	3.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2	8.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2	6.6	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2	1.0	GO:0004144	2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.2	1.8	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.2	3.3	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.2	0.4	GO:0070573	metallodipeptidase activity(GO:0070573)
0.2	4.7	GO:0061733	histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.2	4.8	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.2	6.8	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2	0.8	GO:0045502	dynein binding(GO:0045502)
0.2	1.1	GO:0030274	LIM domain binding(GO:0030274)
0.2	3.4	GO:0003777	microtubule motor activity(GO:0003777)
0.2	14.6	GO:0004386	helicase activity(GO:0004386)
0.2	0.6	GO:0070568	guanylyltransferase activity(GO:0070568)
0.2	4.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.2	8.2	GO:0002039	p53 binding(GO:0002039)
0.1	1.6	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	9.0	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1	2.9	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	4.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	13.2	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	5.0	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.1	35.1	GO:0003779	actin binding(GO:0003779)
0.1	2.5	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	1.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	4.5	GO:0042162	telomeric DNA binding(GO:0042162)
0.1	2.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	1.8	GO:0071837	HMG box domain binding(GO:0071837)
0.1	5.3	GO:0034062	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1	1.9	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	3.5	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	5.6	GO:1990782	protein tyrosine kinase binding(GO:1990782)
0.1	1.8	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	4.3	GO:0003684	damaged DNA binding(GO:0003684)
0.1	1.0	GO:0022839	ion gated channel activity(GO:0022839)
0.1	1.9	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	12.4	GO:0016503	pheromone receptor activity(GO:0016503)
0.1	5.8	GO:0070888	E-box binding(GO:0070888)
0.1	3.0	GO:0030544	Hsp70 protein binding(GO:0030544)
0.1	14.4	GO:0042393	histone binding(GO:0042393)
0.1	4.3	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.1	7.0	GO:0001948	glycoprotein binding(GO:0001948)
0.1	1.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	52.4	GO:0005509	calcium ion binding(GO:0005509)
0.1	1.7	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	2.2	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.1	3.4	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	4.7	GO:0008146	sulfotransferase activity(GO:0008146)
0.1	3.2	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	1.1	GO:0008061	chitin binding(GO:0008061)
0.1	4.0	GO:0019887	protein kinase regulator activity(GO:0019887)
0.1	0.7	GO:0034511	U3 snoRNA binding(GO:0034511)
0.1	4.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	1.5	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.1	5.4	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.1	2.6	GO:0005109	frizzled binding(GO:0005109)
0.1	2.1	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1	3.5	GO:0005262	calcium channel activity(GO:0005262)
0.1	1.5	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.9	GO:0033558	histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1	0.5	GO:0070403	NAD+ binding(GO:0070403)
0.1	1.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	3.2	GO:0051082	unfolded protein binding(GO:0051082)
0.1	1.2	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.9	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	2.2	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0052870	leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.0	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.3	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	3.2	GO:0005267	potassium channel activity(GO:0005267)
0.0	0.3	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	6.7	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.0	5.0	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.8	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.0	0.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0016936	galactoside binding(GO:0016936)
0.0	0.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	35.6	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
2.2	48.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
2.2	86.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
2.0	75.1	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
1.6	33.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.1	47.5	PID AURORA B PATHWAY	Aurora B signaling
1.0	1.9	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
1.0	47.0	NABA COLLAGENS	Genes encoding collagen proteins
0.9	9.6	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.8	9.7	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.8	17.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.7	7.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.7	25.9	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.6	31.7	PID EPHB FWD PATHWAY	EPHB forward signaling
0.6	8.2	PID S1P S1P1 PATHWAY	S1P1 pathway
0.6	4.9	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.6	24.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.6	34.0	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.6	5.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.6	5.7	PID IL5 PATHWAY	IL5-mediated signaling events
0.6	13.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.6	20.0	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.5	28.2	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.5	13.0	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.5	12.8	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.4	7.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.4	2.4	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.4	22.0	PID CDC42 PATHWAY	CDC42 signaling events
0.4	5.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.4	6.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.4	3.7	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.4	6.3	PID ARF6 PATHWAY	Arf6 signaling events
0.4	3.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.4	4.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.3	3.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	1.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.3	2.6	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.3	5.8	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.3	8.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.3	5.0	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.3	20.6	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.3	6.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.3	2.4	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.3	12.1	PID LKB1 PATHWAY	LKB1 signaling events
0.3	9.9	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.2	2.7	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2	6.5	PID TNF PATHWAY	TNF receptor signaling pathway
0.2	39.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	9.7	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.2	10.3	PID BMP PATHWAY	BMP receptor signaling
0.2	5.0	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.2	12.6	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.2	3.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.2	4.1	PID RHOA PATHWAY	RhoA signaling pathway
0.2	2.5	ST ADRENERGIC	Adrenergic Pathway
0.2	2.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.2	3.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2	0.8	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	5.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.1	3.3	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	3.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	4.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	1.6	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	3.6	PID ENDOTHELIN PATHWAY	Endothelins
0.1	1.9	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	2.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	4.1	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	1.2	PID AURORA A PATHWAY	Aurora A signaling
0.1	1.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	3.3	PID ATM PATHWAY	ATM pathway
0.1	1.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	2.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	1.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	2.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	0.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	0.5	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	0.7	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.1	0.6	PID SHP2 PATHWAY	SHP2 signaling
0.0	2.2	PID E2F PATHWAY	E2F transcription factor network
0.0	6.1	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.6	PID NOTCH PATHWAY	Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	58.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
2.6	21.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
2.3	41.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
2.1	20.5	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
2.0	23.8	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
1.8	3.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
1.6	26.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.6	43.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
1.4	17.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
1.3	10.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
1.2	49.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
1.2	24.7	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
1.2	17.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.2	21.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
1.2	18.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
1.2	19.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
1.1	9.9	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
1.1	11.8	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
1.1	24.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
1.0	5.2	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.0	31.8	REACTOME KINESINS	Genes involved in Kinesins
1.0	8.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.9	7.6	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.9	37.1	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.9	10.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.9	5.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.9	11.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.9	11.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.8	3.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.8	2.4	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.8	1.6	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.8	8.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.7	7.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.7	10.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.7	1.5	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.7	10.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.7	5.0	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.7	18.0	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.7	13.1	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.7	7.8	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.7	37.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.6	18.8	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.6	2.6	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.6	41.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.6	8.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.6	10.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.6	47.2	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.6	9.2	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.6	5.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.6	33.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.6	18.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.6	33.5	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.6	8.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.6	6.8	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.6	4.0	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.6	12.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.6	6.6	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.5	8.7	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.5	21.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.5	15.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.5	24.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.5	5.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.5	9.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.5	5.4	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.5	9.2	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.5	7.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.4	7.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.4	7.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.4	5.2	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.4	6.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.4	2.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.4	3.4	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.4	8.2	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.4	5.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.4	45.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.3	8.0	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.3	6.3	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.3	5.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.3	2.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.3	3.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.3	3.8	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.3	3.9	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.3	10.6	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
0.3	2.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.3	1.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	6.8	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.2	5.8	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	6.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.2	1.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.2	1.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.2	25.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.2	3.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	5.0	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.2	2.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	3.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	2.9	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.2	1.2	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.2	6.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.2	4.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	2.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.2	3.5	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	7.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	0.9	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.2	2.8	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.1	5.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	3.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	5.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	4.6	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.1	8.3	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	1.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	3.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	1.5	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.1	1.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	4.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	3.5	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.1	0.7	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	3.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	1.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	2.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	1.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	1.5	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	0.5	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.1	1.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.8	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.8	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.1	0.3	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	2.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	0.9	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	1.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	1.4	REACTOME TRANSLATION	Genes involved in Translation
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.4	REACTOME MEIOSIS	Genes involved in Meiosis

Results for Sox2

Z-value: 1.57

Motif logo

Transcription factors associated with Sox2

Activity-expression correlation:

Activity profile of Sox2 motif

Sorted Z-values of Sox2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: