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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Sox21

Z-value: 1.31

Motif logo

Transcription factors associated with Sox21

Gene Symbol Gene ID Gene Info
ENSRNOG00000052579 Sox21

Activity profile of Sox21 motif

Sorted Z-values of Sox21 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_17889972 96.28 ENSRNOT00000073021

chr8_-_114617466 73.44 ENSRNOT00000082992
ENSRNOT00000038160
collagen type VI alpha 5 chain
chr2_-_173668555 59.00 ENSRNOT00000013452
serpin family I member 2
chr4_+_14109864 57.84 ENSRNOT00000076349
similar to fatty acid translocase/CD36
chr6_-_138536321 56.59 ENSRNOT00000077743

chr6_-_138249382 52.78 ENSRNOT00000085678
ENSRNOT00000006912
immunoglobulin heavy constant mu
chr6_+_139177200 48.45 ENSRNOT00000084131

chr6_-_140715174 47.46 ENSRNOT00000085345

chr6_+_139209936 43.06 ENSRNOT00000087620

chr3_+_16846412 40.82 ENSRNOT00000074266

chr4_+_98481520 38.04 ENSRNOT00000078381
ENSRNOT00000048493

chr1_+_22332090 37.32 ENSRNOT00000091252
trace amine-associated receptor 8c (Taar8c), mRNA
chr3_+_17546566 36.90 ENSRNOT00000050825

chr9_+_8054466 36.23 ENSRNOT00000081513
adhesion G protein-coupled receptor E4
chr7_-_14418950 34.73 ENSRNOT00000066722
RAS protein activator like 3
chr5_+_157222636 32.93 ENSRNOT00000022579
phospholipase A2, group IID
chr6_+_139345486 32.81 ENSRNOT00000081540

chr13_+_92264231 32.49 ENSRNOT00000066509
ENSRNOT00000004716
spectrin, alpha, erythrocytic 1
chr3_+_20007192 32.39 ENSRNOT00000075229

chr6_-_138550576 30.61 ENSRNOT00000075284

chr4_-_163762434 30.09 ENSRNOT00000081854
immunoreceptor Ly49si1
chr8_+_5768811 29.42 ENSRNOT00000013936
matrix metallopeptidase 8
chr6_-_138536162 29.18 ENSRNOT00000083031

chr6_-_139654508 26.65 ENSRNOT00000082576

chr6_-_138909105 25.89 ENSRNOT00000087855

chr6_-_138948583 25.85 ENSRNOT00000084614

chr14_+_108826831 25.37 ENSRNOT00000083146
ENSRNOT00000009421
B-cell CLL/lymphoma 11A
chr6_-_138852571 24.72 ENSRNOT00000081803

chr17_-_43776460 23.67 ENSRNOT00000089055
histone cluster 2, H3c2
chr19_-_37796089 23.57 ENSRNOT00000024891
RAN binding protein 10
chr6_-_138679665 22.31 ENSRNOT00000086777

chr6_-_142372031 21.88 ENSRNOT00000063929

chr10_+_30038709 21.15 ENSRNOT00000005898
interleukin 12B
chr1_+_242959488 19.88 ENSRNOT00000015668
dedicator of cytokinesis 8
chr17_-_86657473 19.45 ENSRNOT00000078827

chr3_+_17139670 18.76 ENSRNOT00000073316

chr3_+_16590244 18.27 ENSRNOT00000073229

chr3_+_172550258 18.08 ENSRNOT00000075148
tubulin, beta 1 class VI
chrX_+_104684676 18.06 ENSRNOT00000083229
tenomodulin
chr20_-_45260119 18.02 ENSRNOT00000000718
solute carrier family 16 member 10
chr1_+_253221812 17.20 ENSRNOT00000085880
ENSRNOT00000054753
kinesin family member 20B
chr6_-_86914883 16.29 ENSRNOT00000091202
MIS18 binding protein 1
chr20_-_4792283 16.10 ENSRNOT00000061027
RT1 class I, locus1
chr4_+_93959152 16.02 ENSRNOT00000058437

chr5_-_12172009 14.43 ENSRNOT00000061903
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr8_+_48665652 13.75 ENSRNOT00000059715
H2A histone family, member X
chr1_-_118826977 13.64 ENSRNOT00000079274

chr4_-_13878126 13.14 ENSRNOT00000007032
G protein subunit alpha transducin 3
chr2_-_127710448 11.72 ENSRNOT00000093733
major facilitator superfamily domain containing 8
chr6_-_125723732 11.52 ENSRNOT00000084815
fibulin 5
chr4_-_168517177 11.48 ENSRNOT00000009151
dual specificity phosphatase 16
chr6_+_135513650 11.27 ENSRNOT00000010676
REST corepressor 1
chr4_-_164899041 11.08 ENSRNOT00000090316
Ly49 inhibitory receptor 2
chr1_+_75428027 10.41 ENSRNOT00000058334
phospholipase A2, group IVC
chr20_-_4792450 10.19 ENSRNOT00000091344
RT1 class I, locus CE6
chr1_-_64090017 9.70 ENSRNOT00000086622
ENSRNOT00000091654
ribosomal protein S9
chr13_-_61306939 9.69 ENSRNOT00000086610
regulator of G-protein signaling 21
chr4_+_153217782 9.11 ENSRNOT00000015499
CECR2, histone acetyl-lysine reader
chr1_-_53152866 9.04 ENSRNOT00000085501
Fgfr1 oncogene partner
chr15_+_80040842 8.71 ENSRNOT00000043065
similar to RIKEN cDNA 4921530L21
chr15_-_27968358 8.61 ENSRNOT00000040616
ribonuclease A family member 9
chr8_-_104155775 8.38 ENSRNOT00000042885
60S ribosomal protein L31-like
chr1_-_141504111 8.33 ENSRNOT00000040164
small nuclear ribonucleoprotein polypeptide E pseudogene 2
chr17_-_51912496 8.30 ENSRNOT00000019272
inhibin beta A subunit
chr15_-_82581916 7.96 ENSRNOT00000057891
similar to ribosomal protein L27
chr2_-_248484100 7.91 ENSRNOT00000040856
guanylate binding protein 3
chr10_-_35187416 7.82 ENSRNOT00000084509
CCR4-NOT transcription complex, subunit 6
chr3_-_111080705 7.57 ENSRNOT00000079339
ras homolog family member V
chrX_-_10031167 7.54 ENSRNOT00000060988
G protein-coupled receptor 34
chr2_-_118882562 7.48 ENSRNOT00000058860
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr18_-_1828606 7.35 ENSRNOT00000033312
establishment of sister chromatid cohesion N-acetyltransferase 1
chr4_-_165118062 7.32 ENSRNOT00000087219
Ly49s8
chr6_+_12179227 7.26 ENSRNOT00000061693
forkhead box N2
chr20_+_4329811 6.97 ENSRNOT00000000513
notch 4
chr3_+_47439076 6.94 ENSRNOT00000011794
TRAF family member-associated NFKB activator
chr4_-_147122060 6.86 ENSRNOT00000047694

chr3_+_94585873 6.82 ENSRNOT00000076762
cleavage stimulation factor subunit 3
chr11_+_2645865 6.60 ENSRNOT00000000905
POU class 1 homeobox 1
chr13_-_91228901 6.54 ENSRNOT00000071728
ENSRNOT00000073643
ENSRNOT00000071897
low affinity immunoglobulin gamma Fc region receptor III-like
chr7_-_104541392 6.54 ENSRNOT00000078116
family with sequence similarity 49, member B
chr3_-_132282879 6.51 ENSRNOT00000042040
high-mobility group nucleosomal binding domain 2-like
chr10_-_1461216 6.47 ENSRNOT00000083125
ENSRNOT00000084447
ENSRNOT00000078421
poly(A)-specific ribonuclease
chr13_-_52413681 6.34 ENSRNOT00000037100
ENSRNOT00000011801
neuron navigator 1
chr10_-_103619083 6.23 ENSRNOT00000029092
Cd300e molecule
chr12_-_21450204 5.95 ENSRNOT00000065866
zinc finger CW-type PWWP domain protein 1-like
chr5_-_120083904 5.79 ENSRNOT00000064542
Janus kinase 1
chr10_+_65552897 5.57 ENSRNOT00000056217
sperm associated antigen 5
chr3_+_22964230 5.50 ENSRNOT00000041813
ribosomal protein S20-like
chr10_-_66873948 5.47 ENSRNOT00000039261
ecotropic viral integration site 2A
chr4_+_88026033 5.37 ENSRNOT00000074905
vomeronasal 1 receptor 80
chr1_-_219544328 5.33 ENSRNOT00000025847
G protein-coupled receptor kinase 2
chrY_-_1398030 5.31 ENSRNOT00000088719
ubiquitin specific peptidase 9, Y-linked
chr15_-_57651041 5.09 ENSRNOT00000072138
spermatid associated
chr7_-_60122805 5.04 ENSRNOT00000037946
chaperonin containing TCP1 subunit 2
chr6_-_12997817 5.03 ENSRNOT00000022802
follicle stimulating hormone receptor
chr1_-_102845083 5.03 ENSRNOT00000082289
serum amyloid A4
chr3_-_60023913 5.00 ENSRNOT00000064662
corepressor interacting with RBPJ, 1
chr4_+_136078391 4.93 ENSRNOT00000048672

chr1_+_102924059 4.82 ENSRNOT00000078137

chr3_+_98695503 4.79 ENSRNOT00000042764

chr7_+_38900593 4.69 ENSRNOT00000072166
epiphycan
chr5_+_131915382 4.66 ENSRNOT00000087012
selection and upkeep of intraepithelial T cells 1
chr12_+_8725517 4.65 ENSRNOT00000001243
solute carrier family 46, member 3
chr1_-_172567846 4.62 ENSRNOT00000012974
olfactory receptor 259
chr10_-_87286387 4.62 ENSRNOT00000044206
keratin 28
chr13_+_110372164 4.48 ENSRNOT00000049634
similar to ribosomal protein L37
chr5_+_150787043 4.42 ENSRNOT00000082945
EYA transcriptional coactivator and phosphatase 3
chr2_+_54466280 4.28 ENSRNOT00000033112
complement C6
chr1_+_88955135 4.00 ENSRNOT00000083550
proline dehydrogenase 2
chr11_+_47061354 3.99 ENSRNOT00000039997
PEST proteolytic signal containing nuclear protein
chr15_-_27140657 3.97 ENSRNOT00000016727
olfactory receptor 1612
chrX_+_54062935 3.75 ENSRNOT00000004854
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr1_+_88955440 3.75 ENSRNOT00000091101
proline dehydrogenase 2
chr5_+_121952977 3.72 ENSRNOT00000008278
phosphodiesterase 4B
chr16_+_50152008 3.71 ENSRNOT00000019237
kallikrein B1
chr3_+_43255567 3.69 ENSRNOT00000044419
glycerol-3-phosphate dehydrogenase 2
chr4_-_119131202 3.68 ENSRNOT00000011675
anthrax toxin receptor 1
chrX_-_122062799 3.53 ENSRNOT00000086852
predicted gene 4907
chr1_-_256914260 3.51 ENSRNOT00000020620
FRA10A associated CGG repeat 1
chr18_-_58081096 3.37 ENSRNOT00000059276
serine peptidase inhibitor, Kazal type 13 (putative)
chr1_+_281863918 3.35 ENSRNOT00000030108
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
chr17_-_76281660 3.28 ENSRNOT00000058070
UPF2 regulator of nonsense transcripts homolog (yeast)
chr2_-_27343998 3.24 ENSRNOT00000091418
DNA polymerase kappa
chr8_-_21224737 3.18 ENSRNOT00000067321
olfactory receptor, family 7, subfamily E, member 24
chr3_-_48604097 3.06 ENSRNOT00000009620
interferon induced with helicase C domain 1
chr3_-_102996314 2.99 ENSRNOT00000046265
olfactory receptor 774
chr3_-_75576520 2.99 ENSRNOT00000083330
olfactory receptor 567
chr10_+_82032656 2.93 ENSRNOT00000067751
ankyrin repeat domain 40
chr2_+_100677411 2.88 ENSRNOT00000067556
YTH N(6)-methyladenosine RNA binding protein 3
chr4_+_146598413 2.85 ENSRNOT00000067532
autophagy related 7
chr4_+_52235811 2.76 ENSRNOT00000060478
hyaluronoglucosaminidase 5
chr1_+_227892956 2.66 ENSRNOT00000028483

chr10_+_10457320 2.60 ENSRNOT00000003832
RNA binding motif protein 25-like 1
chr20_-_34679779 2.53 ENSRNOT00000078420
centrosomal protein 85-like
chr9_-_121972055 2.50 ENSRNOT00000089735
clusterin-like protein 1
chr3_-_78271875 2.49 ENSRNOT00000008475
olfactory receptor 701
chr10_-_74388787 2.40 ENSRNOT00000008107
SMG8 nonsense mediated mRNA decay factor
chr7_-_8810649 2.31 ENSRNOT00000050023
olfactory receptor 937
chr3_-_111587151 2.23 ENSRNOT00000007299
RNA polymerase II associated protein 1
chr10_-_58771908 2.19 ENSRNOT00000018808
similar to 4933427D14Rik protein
chr1_-_37957400 2.17 ENSRNOT00000085560
ENSRNOT00000079626
ENSRNOT00000071889
zinc finger protein 91-like
chr7_-_145062956 2.16 ENSRNOT00000055274
similar to CDNA sequence BC048502
chr1_-_167992529 2.13 ENSRNOT00000067344
similar to olfactory receptor 566
chr8_-_77398156 2.13 ENSRNOT00000091858
ENSRNOT00000085349
ENSRNOT00000082763
lipase C, hepatic type
chr1_-_22452301 2.06 ENSRNOT00000043436
trace amine-associated receptor 7h
chr1_+_168005316 2.03 ENSRNOT00000020678
olfactory receptor 51
chr1_+_222844144 2.03 ENSRNOT00000032879
phospholipase A2, group XVI
chr14_-_66771750 2.02 ENSRNOT00000005587
PARK2 co-regulated-like
chr7_+_5324469 2.00 ENSRNOT00000071164
olfactory receptor 901
chrX_-_143558521 1.99 ENSRNOT00000056598
hypothetical protein LOC688842
chr15_+_27207645 1.95 ENSRNOT00000011549
olfactory receptor 1614
chr9_-_117867557 1.93 ENSRNOT00000056321

chr3_+_76237607 1.93 ENSRNOT00000067444
olfactory receptor 606
chr2_-_61698007 1.92 ENSRNOT00000049559
LRRGT00045
chr17_+_53965562 1.83 ENSRNOT00000090387
geranylgeranyl diphosphate synthase 1
chr9_+_42945358 1.64 ENSRNOT00000059806
fer-1-like family member 5
chr13_-_83457888 1.37 ENSRNOT00000076289
ENSRNOT00000004065
SFT2 domain containing 2
chr10_-_63240332 1.30 ENSRNOT00000005125
bleomycin hydrolase
chr1_-_173456488 1.28 ENSRNOT00000044753
olfactory receptor 282
chr19_+_32770655 1.22 ENSRNOT00000071471
Sm protein F-like
chr3_-_102826379 1.19 ENSRNOT00000073423
olfactory receptor 769
chr9_-_105282292 1.17 ENSRNOT00000071358
solute carrier organic anion transporter family member 6A1-like
chr3_-_73523043 1.10 ENSRNOT00000012959
olfactory receptor 484
chr12_+_48677905 1.08 ENSRNOT00000083196
RIKEN cDNA 1700069L16 gene
chr7_+_116671948 1.08 ENSRNOT00000077773
ENSRNOT00000029711
GLI family zinc finger 4
chr3_-_76289390 1.05 ENSRNOT00000051968
olfactory receptor 609
chr10_-_12777245 1.03 ENSRNOT00000041708
olfactory receptor 1380
chr3_+_16117228 1.00 ENSRNOT00000049590
olfactory receptor 404
chr4_+_1566448 0.99 ENSRNOT00000088227
olfactory receptor 1243
chrX_-_120521871 0.93 ENSRNOT00000080863
LRRGT00025-like
chr5_+_162351001 0.92 ENSRNOT00000065471
hypothetical protein LOC691162
chr19_+_22699808 0.90 ENSRNOT00000023169
similar to RIKEN cDNA 4921524J17
chr7_-_101214630 0.89 ENSRNOT00000042213
Ac2-224
chr1_-_22404002 0.82 ENSRNOT00000044098
trace amine-associated receptor 8a
chr13_-_34251650 0.80 ENSRNOT00000068524
translin
chr1_+_42121636 0.79 ENSRNOT00000025616
myc target 1
chr6_+_29061618 0.75 ENSRNOT00000092223
ATPase family, AAA domain containing 2B
chr3_-_61488696 0.75 ENSRNOT00000083045
lunapark, ER junction formation factor
chr1_+_229722768 0.60 ENSRNOT00000017126
olfactory receptor 339
chr8_+_118525682 0.56 ENSRNOT00000028288
elongator acetyltransferase complex subunit 6
chr17_+_39509516 0.56 ENSRNOT00000022797
prolactin family 8, subfamily a, member 7
chr10_-_98544447 0.50 ENSRNOT00000073149
ATP binding cassette subfamily A member 6
chr1_-_84950210 0.47 ENSRNOT00000083050

chr8_+_128577080 0.45 ENSRNOT00000024172
WD repeat domain 48
chr8_+_40258985 0.44 ENSRNOT00000044652
olfactory receptor 1196
chr16_-_84406538 0.39 ENSRNOT00000051980
LRRG00131
chr7_+_6068010 0.39 ENSRNOT00000044587
olfactory receptor 1007
chr2_+_149899538 0.33 ENSRNOT00000065365
similar to hypothetical protein C130079G13
chr9_-_8899144 0.28 ENSRNOT00000051043

chr2_-_3124543 0.27 ENSRNOT00000036547
family with sequence similarity 81, member B
chr8_+_18926418 0.22 ENSRNOT00000044686
olfactory receptor 1128
chr13_-_34251942 0.15 ENSRNOT00000044095
translin
chr7_+_73273985 0.14 ENSRNOT00000077730
POP1 homolog, ribonuclease P/MRP subunit
chr3_-_103090390 0.12 ENSRNOT00000045645
olfactory receptor 777
chr3_+_76052230 0.07 ENSRNOT00000039963
olfactory receptor 5W2-like
chr3_+_31802999 0.02 ENSRNOT00000041305

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.0 55.9 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
8.5 25.4 GO:1903860 negative regulation of dendrite extension(GO:1903860)
5.7 17.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
3.6 18.0 GO:0015801 aromatic amino acid transport(GO:0015801)
3.0 18.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
2.6 7.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.4 9.7 GO:0045903 positive regulation of translational fidelity(GO:0045903)
2.4 32.9 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
2.3 6.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
2.2 13.1 GO:0050917 sensory perception of umami taste(GO:0050917)
2.2 6.5 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
2.2 8.6 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
2.1 8.3 GO:0060279 positive regulation of ovulation(GO:0060279)
1.8 7.3 GO:0034421 post-translational protein acetylation(GO:0034421)
1.7 7.0 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
1.7 5.0 GO:0001545 primary ovarian follicle growth(GO:0001545)
1.6 6.6 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
1.6 7.8 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.4 4.3 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
1.3 5.0 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
1.2 29.4 GO:0030574 collagen catabolic process(GO:0030574)
1.2 5.8 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.2 11.5 GO:0048251 elastic fiber assembly(GO:0048251)
1.1 11.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.0 19.9 GO:0001771 immunological synapse formation(GO:0001771)
1.0 32.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.9 2.8 GO:0080144 amino acid homeostasis(GO:0080144)
0.9 23.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.8 9.1 GO:0001842 neural fold formation(GO:0001842)
0.8 5.3 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.7 3.7 GO:0019563 glycerol catabolic process(GO:0019563)
0.7 3.7 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.7 2.1 GO:0010034 response to acetate(GO:0010034)
0.6 3.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.6 1.8 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.5 3.7 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.5 4.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.5 3.4 GO:0060467 negative regulation of fertilization(GO:0060467)
0.5 3.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.5 3.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.4 4.7 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.4 7.5 GO:0005513 detection of calcium ion(GO:0005513)
0.4 2.8 GO:0007341 penetration of zona pellucida(GO:0007341)
0.4 3.1 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.3 5.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 13.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.3 9.0 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 6.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.3 1.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.2 18.1 GO:0051225 spindle assembly(GO:0051225)
0.2 11.7 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2 55.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.2 5.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 2.0 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.2 5.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.4 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.1 1.8 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 7.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 2.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 43.9 GO:0006955 immune response(GO:0006955)
0.0 0.1 GO:0016078 tRNA 5'-leader removal(GO:0001682) tRNA catabolic process(GO:0016078)
0.0 3.8 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 1.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 3.9 GO:0008380 RNA splicing(GO:0008380)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 32.5 GO:0014731 spectrin(GO:0008091) spectrin-associated cytoskeleton(GO:0014731) cuticular plate(GO:0032437)
2.8 8.3 GO:0043511 inhibin complex(GO:0043511)
2.3 11.5 GO:0071953 elastic fiber(GO:0071953)
2.0 34.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
1.3 16.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
1.2 17.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.8 9.1 GO:0031010 ISWI-type complex(GO:0031010)
0.7 3.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.7 13.7 GO:0001741 XY body(GO:0001741)
0.6 4.3 GO:0005579 membrane attack complex(GO:0005579)
0.5 3.3 GO:0001651 dense fibrillar component(GO:0001651)
0.4 7.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.4 5.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.3 6.3 GO:0043194 axon initial segment(GO:0043194)
0.3 17.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 7.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 11.3 GO:1990391 DNA repair complex(GO:1990391)
0.2 13.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 7.8 GO:0034451 centriolar satellite(GO:0034451)
0.2 90.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 3.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 3.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 9.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 2.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 23.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 76.3 GO:0005615 extracellular space(GO:0005615)
0.1 5.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.4 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 49.1 GO:0009986 cell surface(GO:0009986)
0.0 4.6 GO:0005882 intermediate filament(GO:0005882)
0.0 10.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 23.5 GO:0016604 nuclear body(GO:0016604)
0.0 2.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 7.6 GO:0010008 endosome membrane(GO:0010008)
0.0 2.6 GO:0005681 spliceosomal complex(GO:0005681)
0.0 2.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.2 GO:0031252 cell leading edge(GO:0031252)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 23.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
3.6 14.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
3.0 18.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
2.6 7.7 GO:0004657 proline dehydrogenase activity(GO:0004657)
2.5 5.0 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
2.3 6.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
2.2 6.5 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
2.1 8.3 GO:0070699 type II activin receptor binding(GO:0070699)
1.9 9.7 GO:1990932 5.8S rRNA binding(GO:1990932)
1.5 35.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.2 3.7 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
1.2 5.8 GO:0005131 growth hormone receptor binding(GO:0005131)
1.1 9.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
1.1 3.3 GO:0034512 box C/D snoRNA binding(GO:0034512)
1.1 17.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.9 5.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.8 14.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.7 11.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 6.5 GO:0019864 IgG binding(GO:0019864)
0.5 62.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 2.0 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 1.8 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.4 2.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 2.8 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.3 7.0 GO:0005112 Notch binding(GO:0005112)
0.3 2.8 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 36.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 17.0 GO:0003684 damaged DNA binding(GO:0003684)
0.2 25.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 6.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 3.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 21.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.2 6.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 5.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 2.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 18.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 7.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 4.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 31.3 GO:0005096 GTPase activator activity(GO:0005096)
0.1 3.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 8.7 GO:0004540 ribonuclease activity(GO:0004540)
0.1 9.9 GO:0005178 integrin binding(GO:0005178)
0.1 27.5 GO:0030246 carbohydrate binding(GO:0030246)
0.1 46.9 GO:0005509 calcium ion binding(GO:0005509)
0.1 3.7 GO:0005518 collagen binding(GO:0005518)
0.1 2.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 3.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 14.3 GO:0045296 cadherin binding(GO:0045296)
0.0 1.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 6.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.3 GO:0003924 GTPase activity(GO:0003924)
0.0 3.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.5 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 73.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.9 26.9 PID IL27 PATHWAY IL27-mediated signaling events
0.4 11.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.4 3.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 84.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 13.7 PID ATM PATHWAY ATM pathway
0.3 8.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 12.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 7.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 7.0 PID NOTCH PATHWAY Notch signaling pathway
0.1 4.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 6.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 5.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 45.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
1.2 23.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.2 33.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.9 30.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.8 5.0 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.8 8.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.7 30.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.6 14.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.6 7.0 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.5 3.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.5 10.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.5 18.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 5.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 9.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.3 6.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.3 7.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 9.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 2.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 4.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 3.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 5.7 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 9.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 3.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 3.7 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism