Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Sp2

Z-value: 0.81

Motif logo

Transcription factors associated with Sp2

Gene Symbol Gene ID Gene Info
ENSRNOG00000010492 Sp2 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sp2rn6_v1_chr10_-_84920886_84920886-0.612.4e-34Click!

Activity profile of Sp2 motif

Sorted Z-values of Sp2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_80195532 53.95 ENSRNOT00000022528
reticulon 2
chr6_+_137184820 31.03 ENSRNOT00000073796
adenylosuccinate synthase like 1
chr13_-_90602365 30.65 ENSRNOT00000009344
calsequestrin 1
chr10_-_8498422 27.83 ENSRNOT00000082332
RNA binding protein, fox-1 homolog 1
chr1_-_80609836 20.58 ENSRNOT00000091647
ENSRNOT00000046169
apolipoprotein C1
chr13_+_104284660 20.39 ENSRNOT00000005400
dual specificity phosphatase 10
chr12_+_45905371 20.10 ENSRNOT00000039275
heat shock protein family B (small) member 8
chr15_+_34251606 19.87 ENSRNOT00000025725
fat storage-inducing transmembrane protein 1
chr2_-_53413638 18.81 ENSRNOT00000021081
growth hormone receptor
chr1_-_198232344 17.52 ENSRNOT00000080988
aldolase, fructose-bisphosphate A
chr8_-_53146953 16.63 ENSRNOT00000045356
zinc finger and BTB domain containing 16
chr8_-_25904564 16.60 ENSRNOT00000082744
ENSRNOT00000064783
T-box 20
chr9_+_74124016 16.42 ENSRNOT00000019023
carbamoyl-phosphate synthase 1
chr1_-_215836641 16.19 ENSRNOT00000080246
insulin-like growth factor 2
chr3_+_111160205 15.79 ENSRNOT00000019392
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
chr7_+_117759083 14.48 ENSRNOT00000050556
glutamic--pyruvic transaminase
chr7_+_26375866 14.45 ENSRNOT00000059639
aldehyde dehydrogenase 1 family, member L2
chr10_+_56445647 13.70 ENSRNOT00000056870
transmembrane protein 256
chr18_-_28444880 11.93 ENSRNOT00000060696
proline rich basic protein 1
chrX_-_134866210 11.09 ENSRNOT00000005331
apelin
chr19_+_31524671 10.69 ENSRNOT00000024616
Hedgehog-interacting protein
chr8_+_91464229 10.47 ENSRNOT00000013249
branched chain keto acid dehydrogenase E1 subunit beta
chr11_-_83867203 10.42 ENSRNOT00000002394
chordin
chr20_-_7397448 10.22 ENSRNOT00000059426
similar to chromosome 6 open reading frame 106 isoform a
chr20_-_29199224 9.72 ENSRNOT00000071477
mitochondrial calcium uniporter
chr17_-_78735324 9.22 ENSRNOT00000036299
cerebral dopamine neurotrophic factor
chr9_-_9985630 9.22 ENSRNOT00000071780
crumbs 3, cell polarity complex component
chr19_+_37226186 8.90 ENSRNOT00000075933
ENSRNOT00000065013
heat shock transcription factor 4
chr9_-_17698569 8.89 ENSRNOT00000087528
mitochondrial ribosomal protein L14
chr9_+_65478496 8.77 ENSRNOT00000016060
NADH:ubiquinone oxidoreductase subunit B3
chr3_-_163935617 8.76 ENSRNOT00000074023
potassium voltage-gated channel subfamily B member 1
chr10_-_97896525 8.28 ENSRNOT00000005172
WD repeat domain, phosphoinositide interacting 1
chr2_+_95045034 8.17 ENSRNOT00000081305
mitochondrial ribosomal protein S28
chr9_-_99651813 7.66 ENSRNOT00000022089
NADH:ubiquinone oxidoreductase subunit A10
chr19_-_38321528 7.62 ENSRNOT00000031977
sphingomyelin phosphodiesterase 3
chrX_-_142131545 7.51 ENSRNOT00000077402
fibroblast growth factor 13
chr1_-_64099277 7.24 ENSRNOT00000084846
tRNA splicing endonuclease subunit 34
chr3_+_80362858 7.02 ENSRNOT00000021353
ENSRNOT00000086242
LDL receptor related protein 4
chr13_+_52588917 6.82 ENSRNOT00000011999
pleckstrin homology-like domain, family A, member 3
chr15_-_3435888 6.74 ENSRNOT00000016709
adenosine kinase
chr1_+_141832774 6.65 ENSRNOT00000073302
fucose mutarotase
chr10_-_16689321 6.64 ENSRNOT00000028173
BCL2/adenovirus E1B interacting protein 1
chr10_-_89084885 6.55 ENSRNOT00000027452
pleckstrin homology, MyTH4 and FERM domain containing H3
chrX_-_34794589 6.34 ENSRNOT00000008703
retinoic acid induced 2
chr20_-_5533448 6.33 ENSRNOT00000000568
cutA divalent cation tolerance homolog
chr8_-_85720790 6.32 ENSRNOT00000071049
oocyte expressed protein
chr8_-_22937909 6.21 ENSRNOT00000015684
transmembrane protein 205
chr13_-_91872954 6.16 ENSRNOT00000004613
ENSRNOT00000079263
cell adhesion molecule 3
chr6_-_55647665 5.91 ENSRNOT00000007414
basic leucine zipper and W2 domains 2
chr1_+_101405314 5.85 ENSRNOT00000028194
neurotrophin 4
chr1_-_64030175 5.82 ENSRNOT00000089950
tRNA splicing endonuclease subunit 34-like 1
chr15_+_344360 5.70 ENSRNOT00000077671
potassium calcium-activated channel subfamily M alpha 1
chr15_+_344685 5.69 ENSRNOT00000065542
ENSRNOT00000066928
potassium calcium-activated channel subfamily M alpha 1
chr1_+_126523169 5.67 ENSRNOT00000051000
threonyl-tRNA synthetase-like 2
chr1_+_238843338 5.56 ENSRNOT00000024583
zinc finger AN1-type containing 5
chr17_-_55709740 5.52 ENSRNOT00000033359
similar to OTTHUMP00000046255
chr8_+_36625733 5.47 ENSRNOT00000016248
cell adhesion associated, oncogene regulated
chr1_-_241460868 5.30 ENSRNOT00000054776
similar to RIKEN cDNA 1700028P14
chr2_+_205592182 5.29 ENSRNOT00000081050
DENN domain containing 2C
chr4_-_113610243 5.21 ENSRNOT00000008813
hexokinase 2
chrX_+_157150655 5.15 ENSRNOT00000090795
pregnancy up-regulated nonubiquitous CaM kinase
chr1_-_54748763 5.10 ENSRNOT00000074549
protein MAL2-like
chr3_+_172385672 5.09 ENSRNOT00000090989
GNAS complex locus
chr10_+_12929471 5.06 ENSRNOT00000036563
zinc finger and SCAN domain containing 10
chr2_+_188844073 5.06 ENSRNOT00000028117
potassium calcium-activated channel subfamily N member 3
chr7_+_94130852 5.00 ENSRNOT00000011485
mal, T-cell differentiation protein 2
chr1_-_192025350 4.65 ENSRNOT00000071946
glutamyl-tRNA synthetase 2, mitochondrial
chr7_-_77162148 4.58 ENSRNOT00000008350
Kruppel-like factor 10
chr13_+_103300932 4.57 ENSRNOT00000085214
ENSRNOT00000038264
glutamyl-prolyl-tRNA synthetase
chr8_-_111850393 4.56 ENSRNOT00000044956
CDV3 homolog
chr1_-_264756546 4.53 ENSRNOT00000020020
mitochondrial ribosomal protein L43
chr4_-_152380184 4.52 ENSRNOT00000091473
ELKS/RAB6-interacting/CAST family member 1
chr7_-_98709649 4.48 ENSRNOT00000077440
transmembrane protein 65
chr8_+_115155470 4.46 ENSRNOT00000017139
poly(rC) binding protein 4
chr6_-_55001464 4.43 ENSRNOT00000006618
aryl hydrocarbon receptor
chr7_+_2752680 4.32 ENSRNOT00000033726
citrate synthase
chr8_-_127782070 4.20 ENSRNOT00000045493
phospholipase C, delta 1
chr12_-_25638797 4.18 ENSRNOT00000002033
GATS protein-like 2
chr3_+_151032952 4.17 ENSRNOT00000064013
acyl-CoA synthetase short-chain family member 2
chr1_-_101351879 4.16 ENSRNOT00000028142
PTPRF interacting protein alpha 3
chr16_+_19051965 4.04 ENSRNOT00000016399
solute carrier family 35, member E1
chr9_-_9702306 3.93 ENSRNOT00000082341
thyroid hormone receptor interactor 10
chr13_+_48607308 3.89 ENSRNOT00000063882
solute carrier family 41 member 1
chrX_-_10630281 3.89 ENSRNOT00000080651
ENSRNOT00000048980
ubiquitin specific peptidase 9, X-linked
chrX_+_20484517 3.88 ENSRNOT00000093701
family with sequence similarity 120C
chr2_+_187322416 3.88 ENSRNOT00000025183
cellular retinoic acid binding protein 2
chr9_+_43889473 3.82 ENSRNOT00000024330
inositol polyphosphate-4-phosphatase type I A
chr10_+_46783979 3.74 ENSRNOT00000005237
GID complex subunit 4
chr16_-_71809925 3.70 ENSRNOT00000022425
TM2 domain containing 2
chr6_-_72462657 3.61 ENSRNOT00000088720
ENSRNOT00000077578
striatin 3
chr1_-_221420115 3.60 ENSRNOT00000028475
mitochondrial ribosomal protein L49
chr2_+_233615739 3.59 ENSRNOT00000051009
paired-like homeodomain 2
chr1_+_219759183 3.42 ENSRNOT00000026316
pyruvate carboxylase
chr16_+_71810377 3.42 ENSRNOT00000041330
ADAM metallopeptidase domain 9
chr10_-_59743315 3.41 ENSRNOT00000093646
ER membrane protein complex subunit 6
chr5_-_151768123 3.38 ENSRNOT00000079380
nuclear distribution C, dynein complex regulator
chr5_+_136406308 3.35 ENSRNOT00000072492
ERI1 exoribonuclease family member 3
chr10_-_86004096 3.32 ENSRNOT00000091978
ENSRNOT00000066855
SH3 and cysteine rich domain 2
chr1_+_264756499 3.32 ENSRNOT00000031018
progressive external ophthalmoplegia 1
chr8_+_64364741 3.27 ENSRNOT00000082840
CUGBP, Elav-like family member 6
chr17_+_82065937 3.21 ENSRNOT00000051349
ADP-ribosylation factor like GTPase 5B
chr7_+_144531814 3.20 ENSRNOT00000033300
homeobox C13
chr4_+_77211692 3.10 ENSRNOT00000007620
cullin 1
chr5_+_136406130 3.10 ENSRNOT00000093099
ERI1 exoribonuclease family member 3
chr9_+_45672157 3.05 ENSRNOT00000017882
phosducin-like 3
chr17_+_49610548 3.01 ENSRNOT00000017955
Yae1 domain containing 1
chr1_+_192025357 2.97 ENSRNOT00000025072
ubiquitin family domain containing 1
chr1_+_249574954 2.94 ENSRNOT00000074100
cleavage stimulation factor subunit 2, tau variant
chr8_-_1450138 2.91 ENSRNOT00000008062
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr8_-_111850075 2.87 ENSRNOT00000082097
CDV3 homolog
chr1_-_198120061 2.87 ENSRNOT00000026231
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr6_+_137243185 2.87 ENSRNOT00000030879
zinc finger and BTB domain containing 42
chr5_-_151397603 2.83 ENSRNOT00000076866
G protein-coupled receptor 3
chr5_+_171472273 2.81 ENSRNOT00000055386
multiple epidermal growth factor-like domains protein 6-like
chr4_+_342302 2.81 ENSRNOT00000009233
insulin induced gene 1
chr12_+_38274297 2.80 ENSRNOT00000087905
ENSRNOT00000057788
arginine and serine rich coiled-coil 2
chr2_+_211050360 2.79 ENSRNOT00000026928
proteasome subunit alpha 5
chr1_-_218810118 2.78 ENSRNOT00000065950
ENSRNOT00000020886
protein phosphatase 6, regulatory subunit 3
chr6_+_92568975 2.78 ENSRNOT00000036933
abhydrolase domain containing 12B
chr1_+_165625058 2.76 ENSRNOT00000025104
RAB6A, member RAS oncogene family
chr15_-_33775109 2.70 ENSRNOT00000033722
junctophilin 4
chr16_-_7758189 2.70 ENSRNOT00000026588
2-hydroxyacyl-CoA lyase 1
chr1_-_229639187 2.65 ENSRNOT00000016804
zinc finger protein 91
chr8_+_132441285 2.65 ENSRNOT00000087488
ENSRNOT00000068233
leucyl-tRNA synthetase 2
chrX_-_154722220 2.62 ENSRNOT00000089743
ENSRNOT00000087893
fragile X mental retardation 1
chr5_-_165918445 2.61 ENSRNOT00000018167
peroxisomal biogenesis factor 14
chr19_-_43149210 2.58 ENSRNOT00000038452
pyruvate dehydrogenase phosphatase regulatory subunit
chr17_+_9830332 2.57 ENSRNOT00000021946
RAB24, member RAS oncogene family
chr20_-_10680283 2.55 ENSRNOT00000001579
salt-inducible kinase 1
chr2_+_218951451 2.51 ENSRNOT00000019190
exostosin-like glycosyltransferase 2
chr6_+_104718512 2.31 ENSRNOT00000007947
SPARC related modular calcium binding 1
chr13_+_100817359 2.27 ENSRNOT00000004330
tumor protein p53 binding protein, 2
chrX_-_20070537 2.25 ENSRNOT00000093602
ENSRNOT00000003397
G protein nucleolar 3 like
chr8_+_12994155 2.25 ENSRNOT00000011855
CWC15 spliceosome-associated protein
chr3_+_134413170 2.25 ENSRNOT00000074338

chr2_-_187786700 2.20 ENSRNOT00000092257
ENSRNOT00000092612
ENSRNOT00000068360
solute carrier family 25, member 44
chr8_+_116054465 2.19 ENSRNOT00000040056
cytokine inducible SH2-containing protein
chr5_-_172623899 2.17 ENSRNOT00000080591
SKI proto-oncogene
chr13_+_76942928 2.12 ENSRNOT00000040505
ring finger and WD repeat domain 2
chr10_-_88307132 2.11 ENSRNOT00000040845
junction plakoglobin
chr19_+_55197704 2.05 ENSRNOT00000045657
zinc finger CCCH-type containing 18
chr12_+_22259713 2.00 ENSRNOT00000001913
POP7 homolog, ribonuclease P/MRP subunit
chr1_+_221710670 1.89 ENSRNOT00000064798
mitogen activated protein kinase kinase kinase kinase 2
chr10_-_88307412 1.86 ENSRNOT00000089933
junction plakoglobin
chr5_+_106409456 1.83 ENSRNOT00000058387
focadhesin
chrX_+_156863754 1.81 ENSRNOT00000083611
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr13_-_35048444 1.80 ENSRNOT00000009963
GLI family zinc finger 2
chr8_-_49075892 1.79 ENSRNOT00000082687
archain 1
chr1_-_57489727 1.75 ENSRNOT00000002037
proteasome subunit beta 1
chr10_-_59743037 1.75 ENSRNOT00000026168
ER membrane protein complex subunit 6
chr17_-_67904674 1.74 ENSRNOT00000078532
Kruppel-like factor 6
chr15_+_106257650 1.73 ENSRNOT00000014859
ENSRNOT00000072538
importin 5
chr1_-_100559942 1.73 ENSRNOT00000026862
nuclear receptor subfamily 1, group H, member 2
chr13_+_76943633 1.68 ENSRNOT00000076908
ring finger and WD repeat domain 2
chr20_+_11972381 1.66 ENSRNOT00000001642
adenosine deaminase, RNA-specific, B1
chr2_+_218951141 1.62 ENSRNOT00000091001
exostosin-like glycosyltransferase 2
chr3_+_2676296 1.61 ENSRNOT00000020497
chloride intracellular channel 3
chr16_+_36116258 1.57 ENSRNOT00000017652
Sin3A associated protein 30
chr11_+_46009322 1.57 ENSRNOT00000002233
transmembrane protein 45A
chr14_-_10749120 1.55 ENSRNOT00000003046
COP9 signalosome subunit 4
chr3_+_176989672 1.51 ENSRNOT00000020373
tumor protein D52-like 2
chr20_-_3822754 1.51 ENSRNOT00000000541
ENSRNOT00000077357
solute carrier family 39 member 7
chr9_-_82514399 1.49 ENSRNOT00000026799
aspartyl aminopeptidase
chrX_-_157139291 1.46 ENSRNOT00000092123
solute carrier family 6 member 8
chr10_+_56591292 1.44 ENSRNOT00000023379
CTD nuclear envelope phosphatase 1
chr15_-_93667355 1.44 ENSRNOT00000093571
ENSRNOT00000089876
F-box and leucine-rich repeat protein 3
chr10_-_14324170 1.36 ENSRNOT00000035513
ENSRNOT00000090587
hematological and neurological expressed 1-like
chr3_-_60795951 1.32 ENSRNOT00000002174
activating transcription factor 2
chr5_+_58995249 1.31 ENSRNOT00000023411
coiled-coil domain containing 107
chr7_-_143863186 1.30 ENSRNOT00000017096
retinoic acid receptor, gamma
chr2_+_22427474 1.27 ENSRNOT00000061761
metaxin 3
chr7_+_41114697 1.27 ENSRNOT00000041354
ATPase plasma membrane Ca2+ transporting 1
chr4_-_82141385 1.24 ENSRNOT00000008447
homeobox A3
chr1_+_193076430 1.24 ENSRNOT00000086492
ENSRNOT00000017885
trinucleotide repeat containing 6a
chr17_+_82066152 1.22 ENSRNOT00000083034
ADP-ribosylation factor like GTPase 5B
chr1_+_226742343 1.21 ENSRNOT00000074079
VPS37C, ESCRT-I subunit
chr18_-_6587080 1.20 ENSRNOT00000040815
60S ribosomal protein L39
chr10_-_54467956 1.19 ENSRNOT00000065383
ubiquitin specific peptidase 43
chr4_+_180887182 1.17 ENSRNOT00000042270
ENSRNOT00000002476
FGFR1 oncogene partner 2
chr3_+_56861396 1.13 ENSRNOT00000000008
ENSRNOT00000084375
glutamate decarboxylase 1
chr17_+_86199623 1.12 ENSRNOT00000022727
pancreas specific transcription factor, 1a
chr17_-_18421861 1.11 ENSRNOT00000060500
ENSRNOT00000036560
family with sequence similarity 8, member A1
chr1_+_225163391 1.10 ENSRNOT00000027305
eukaryotic translation elongation factor 1 gamma
chrX_-_152641679 1.10 ENSRNOT00000080277
gamma-aminobutyric acid type A receptor alpha3 subunit
chr5_-_33182147 1.05 ENSRNOT00000080358
MAGE family member D2
chr18_+_65155685 1.01 ENSRNOT00000081797
transcription factor 4
chr3_+_33641616 0.99 ENSRNOT00000051953
enhancer of polycomb homolog 2
chr1_+_198120099 0.97 ENSRNOT00000073652
bolA family member 2
chr14_+_44479614 0.94 ENSRNOT00000003691
UDP-glucose 6-dehydrogenase
chr4_+_153217782 0.83 ENSRNOT00000015499
CECR2, histone acetyl-lysine reader
chr12_+_37923528 0.82 ENSRNOT00000045223
ATP binding cassette subfamily B member 9
chr1_-_214511529 0.78 ENSRNOT00000026390
chitinase domain containing 1
chr19_-_25955371 0.74 ENSRNOT00000004042
ENSRNOT00000084123
RAD23 homolog A, nucleotide excision repair protein
chr10_-_46783889 0.70 ENSRNOT00000004948
ATP synthase mitochondrial F1 complex assembly factor 2
chr16_-_14210449 0.67 ENSRNOT00000016494
coiled-coil serine-rich protein 2
chr5_+_156668712 0.66 ENSRNOT00000067228
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr10_-_82326771 0.66 ENSRNOT00000004673
acyl-CoA synthetase family member 2
chr5_+_136112417 0.61 ENSRNOT00000025990
transmembrane protein 53
chr5_+_47853818 0.59 ENSRNOT00000009228
ENSRNOT00000079656
caspase 8 associated protein 2
chr1_-_92119951 0.51 ENSRNOT00000018153
ENSRNOT00000092121
zinc finger protein 507

Network of associatons between targets according to the STRING database.

First level regulatory network of Sp2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 31.0 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
7.7 30.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
6.7 20.2 GO:0060577 pulmonary vein morphogenesis(GO:0060577)
5.1 20.6 GO:0010916 regulation of phosphatidylcholine catabolic process(GO:0010899) regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
5.1 20.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
4.8 14.4 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
3.8 11.4 GO:0060082 eye blink reflex(GO:0060082)
3.6 14.5 GO:0042853 L-alanine catabolic process(GO:0042853)
3.4 10.2 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
3.3 16.6 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
3.3 16.4 GO:0071400 cellular response to oleic acid(GO:0071400)
3.3 13.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
2.8 19.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
2.8 11.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
2.2 6.7 GO:0044209 purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) AMP salvage(GO:0044209) adenosine biosynthetic process(GO:0046086)
2.2 13.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
2.1 18.8 GO:0006600 allantoin metabolic process(GO:0000255) isoleucine metabolic process(GO:0006549) creatine metabolic process(GO:0006600) creatinine metabolic process(GO:0046449)
2.1 10.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
2.0 15.8 GO:0006751 glutathione catabolic process(GO:0006751)
2.0 13.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.8 7.0 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
1.7 5.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
1.7 6.7 GO:0006004 fucose metabolic process(GO:0006004)
1.5 5.9 GO:0048865 stem cell fate commitment(GO:0048865)
1.4 4.2 GO:0019541 acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
1.4 4.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
1.3 5.2 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.3 3.9 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.3 7.6 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
1.3 17.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.2 27.8 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
1.1 3.4 GO:0051088 positive regulation of macrophage fusion(GO:0034241) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.1 10.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
1.1 4.4 GO:0040009 regulation of growth rate(GO:0040009)
1.1 5.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
1.1 7.5 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
1.0 9.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.9 4.6 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.9 56.6 GO:0065002 intracellular protein transmembrane transport(GO:0065002)
0.9 6.5 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.9 4.5 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.9 2.6 GO:1905244 negative regulation of long term synaptic depression(GO:1900453) regulation of intracellular transport of viral material(GO:1901252) regulation of modification of synaptic structure(GO:1905244)
0.9 10.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.9 3.5 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.9 3.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.8 4.0 GO:0002159 desmosome assembly(GO:0002159)
0.7 2.9 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.7 2.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.6 3.9 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.6 1.8 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.6 2.9 GO:0006553 lysine metabolic process(GO:0006553)
0.5 2.7 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.5 7.5 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.5 3.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.5 2.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.4 1.3 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.4 2.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.4 1.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.4 5.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.4 1.2 GO:0010159 specification of organ position(GO:0010159)
0.4 3.2 GO:0043587 tongue morphogenesis(GO:0043587)
0.4 4.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.4 3.0 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.4 10.7 GO:0045879 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036) negative regulation of smoothened signaling pathway(GO:0045879)
0.4 2.9 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.4 2.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.3 1.7 GO:0048550 negative regulation of pinocytosis(GO:0048550) positive regulation of pancreatic juice secretion(GO:0090187)
0.3 7.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3 0.9 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.3 2.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 3.9 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.3 5.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 1.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 3.4 GO:0007097 nuclear migration(GO:0007097)
0.2 1.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 4.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.2 3.9 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.2 1.7 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.2 3.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 1.3 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.2 1.0 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.2 5.6 GO:0048745 smooth muscle tissue development(GO:0048745)
0.2 2.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 4.5 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.2 1.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.2 1.5 GO:0015871 choline transport(GO:0015871)
0.2 2.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 0.7 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.2 4.6 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.2 1.6 GO:0000338 protein deneddylation(GO:0000338)
0.1 6.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 8.9 GO:0022900 electron transport chain(GO:0022900)
0.1 6.8 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 2.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 6.3 GO:0035088 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.1 2.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.6 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 5.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 1.4 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 6.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 3.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.3 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 0.3 GO:0032258 CVT pathway(GO:0032258)
0.1 0.3 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.8 GO:0001842 neural fold formation(GO:0001842)
0.1 2.8 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 0.8 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 1.0 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.1 0.4 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 1.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 2.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.9 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.1 5.1 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 3.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.5 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 2.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.5 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 1.1 GO:0006414 translational elongation(GO:0006414)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 2.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 3.9 GO:0016236 macroautophagy(GO:0016236)
0.0 0.7 GO:0031648 protein destabilization(GO:0031648)
0.0 2.2 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.2 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 1.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 2.9 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 30.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
3.8 18.8 GO:0070195 growth hormone receptor complex(GO:0070195)
2.6 13.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
2.1 10.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.6 9.7 GO:1990246 uniplex complex(GO:1990246)
1.6 45.2 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
1.3 7.9 GO:0000137 Golgi cis cisterna(GO:0000137)
1.1 20.6 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
1.0 5.2 GO:1903349 omegasome membrane(GO:1903349) omegasome(GO:1990462)
1.0 17.5 GO:0035686 sperm fibrous sheath(GO:0035686)
1.0 4.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
1.0 2.9 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.9 2.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.9 9.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.9 4.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.9 2.6 GO:0097444 spine apparatus(GO:0097444)
0.9 2.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.8 8.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.7 10.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.6 7.0 GO:0016600 flotillin complex(GO:0016600)
0.6 8.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.6 3.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.4 19.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.4 4.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 2.7 GO:0030314 junctional membrane complex(GO:0030314)
0.3 16.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 2.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 17.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 8.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 0.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 1.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 10.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 2.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 19.4 GO:0016605 PML body(GO:0016605)
0.2 39.5 GO:0005802 trans-Golgi network(GO:0005802)
0.2 3.9 GO:0001891 phagocytic cup(GO:0001891)
0.2 3.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 6.6 GO:0031201 SNARE complex(GO:0031201)
0.2 17.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.2 1.8 GO:0097542 ciliary tip(GO:0097542)
0.1 0.9 GO:0031415 NatA complex(GO:0031415)
0.1 3.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.8 GO:0005839 proteasome core complex(GO:0005839)
0.1 5.3 GO:0048786 presynaptic active zone(GO:0048786)
0.1 5.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 5.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 4.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 7.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 21.9 GO:0016607 nuclear speck(GO:0016607)
0.1 10.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.3 GO:0005604 basement membrane(GO:0005604)
0.0 1.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 15.5 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 2.6 GO:0005776 autophagosome(GO:0005776)
0.0 45.6 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 1.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 6.3 GO:0045177 apical part of cell(GO:0045177)
0.0 1.7 GO:0034399 nuclear periphery(GO:0034399)
0.0 12.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.5 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
4.7 18.8 GO:0004903 growth hormone receptor activity(GO:0004903)
3.9 15.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
3.4 10.2 GO:0004827 proline-tRNA ligase activity(GO:0004827)
3.2 9.7 GO:0015292 uniporter activity(GO:0015292)
2.8 11.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
2.7 10.7 GO:0097108 hedgehog family protein binding(GO:0097108)
2.6 13.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
2.5 17.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.3 20.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
1.8 14.4 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
1.7 6.7 GO:0042806 fucose binding(GO:0042806)
1.5 4.4 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
1.4 4.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
1.4 16.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
1.3 10.4 GO:0045545 syndecan binding(GO:0045545)
1.3 20.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.3 3.8 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
1.2 16.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.2 10.5 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
1.1 3.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
1.1 7.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.0 4.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
1.0 21.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.9 2.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.9 5.2 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.9 4.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8 10.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.7 5.9 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.7 5.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.7 31.0 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.6 2.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.6 15.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.5 21.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 6.7 GO:0019206 nucleoside kinase activity(GO:0019206)
0.4 8.8 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.4 1.7 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.4 3.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.4 7.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 2.9 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.4 1.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 3.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.4 2.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.4 3.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 1.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.3 1.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 4.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 1.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 0.9 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.3 2.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.3 11.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 4.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3 3.9 GO:0019841 retinol binding(GO:0019841)
0.3 1.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 7.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 1.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 3.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 3.3 GO:0070410 co-SMAD binding(GO:0070410)
0.2 2.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 8.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 2.6 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 4.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 0.8 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.2 6.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 5.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.9 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 1.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 2.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 11.3 GO:0043130 ubiquitin binding(GO:0043130)
0.1 3.4 GO:0043236 laminin binding(GO:0043236)
0.1 22.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 2.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.8 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 2.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.8 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 1.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 4.4 GO:0005507 copper ion binding(GO:0005507)
0.1 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 9.2 GO:0008083 growth factor activity(GO:0008083)
0.1 1.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 15.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 3.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 6.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 22.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 7.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 2.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0008061 chitin binding(GO:0008061)
0.0 1.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.9 GO:0051287 NAD binding(GO:0051287)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 18.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.5 20.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 19.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 21.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 12.6 PID BMP PATHWAY BMP receptor signaling
0.2 2.2 ST STAT3 PATHWAY STAT3 Pathway
0.2 10.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 4.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 3.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 7.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 4.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 6.0 PID SHP2 PATHWAY SHP2 signaling
0.1 3.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.9 PID TNF PATHWAY TNF receptor signaling pathway
0.1 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 6.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.0 PID FOXO PATHWAY FoxO family signaling
0.0 1.4 PID INSULIN PATHWAY Insulin Pathway
0.0 1.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 6.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 31.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.0 21.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.8 14.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.8 16.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.6 10.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.6 20.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.5 4.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 6.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 7.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.3 16.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 4.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 2.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 10.6 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.2 5.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 7.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 2.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 4.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 6.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 8.2 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 1.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 17.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 5.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 4.0 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 2.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 5.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 14.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 0.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 5.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 3.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.4 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.7 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication