ISMARA results: Tfap2a

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Tfap2a

Z-value: 0.98

Motif logo

Transcription factors associated with Tfap2a

Gene Symbol	Gene ID	Gene Info
Tfap2a NCBI RGD Ensembl	ENSRNOG00000015522	transcription factor AP-2 alpha

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Tfap2a	rn6_v1_chr17_+_24654902_24654902	0.32	3.0e-09	Click!

Activity profile of Tfap2a motif

Sorted Z-values of Tfap2a motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr14_-_60276794 Show fit	21.12	ENSRNOT00000048509	Slc34a2 NCBI RGD Ensembl Show fit	solute carrier family 34 member 2
chr17_+_22619891 Show fit	20.92	ENSRNOT00000060403	Adtrp NCBI RGD Ensembl Show fit	androgen-dependent TFPI-regulating protein
chr2_+_60920257 Show fit	18.84	ENSRNOT00000025170	C1qtnf3 NCBI RGD Ensembl Show fit	C1q and tumor necrosis factor related protein 3
chr2_-_195935878 Show fit	18.62	ENSRNOT00000028440	Cgn NCBI RGD Ensembl Show fit	cingulin
chr1_-_84145916 Show fit	18.45	ENSRNOT00000081796	Ltbp4 NCBI RGD Ensembl Show fit	latent transforming growth factor beta binding protein 4
chr1_-_80716143 Show fit	18.19	ENSRNOT00000092048 ENSRNOT00000025829	Cblc NCBI RGD Ensembl Show fit	Cbl proto-oncogene C
chr10_-_88060561 Show fit	17.65	ENSRNOT00000019133	Krt19 NCBI RGD Ensembl Show fit	keratin 19
chr10_+_104368247 Show fit	15.51	ENSRNOT00000006519	Llgl2 NCBI RGD Ensembl Show fit	LLGL2, scribble cell polarity complex component
chr4_+_120133713 Show fit	15.23	ENSRNOT00000017240	Gata2 NCBI RGD Ensembl Show fit	GATA binding protein 2
chr4_+_72718458 Show fit	14.68	ENSRNOT00000044780	Arhgef5 NCBI RGD Ensembl Show fit	Rho guanine nucleotide exchange factor 5
chr13_-_80745347 Show fit	13.92	ENSRNOT00000041908	Fmo1 NCBI RGD Ensembl Show fit	flavin containing monooxygenase 1
chr8_-_72836159 Show fit	13.88	ENSRNOT00000024617	Tpm1 NCBI RGD Ensembl Show fit	tropomyosin 1, alpha
chr4_+_168832910 Show fit	12.82	ENSRNOT00000011134	Gprc5a NCBI RGD Ensembl Show fit	G protein-coupled receptor, class C, group 5, member A
chr5_+_152559577 Show fit	12.44	ENSRNOT00000082245	Slc30a2 NCBI RGD Ensembl Show fit	solute carrier family 30 member 2
chr15_-_48670257 Show fit	12.36	ENSRNOT00000071464	Fzd3 NCBI RGD Ensembl Show fit	frizzled class receptor 3
chr11_-_57993548 Show fit	12.27	ENSRNOT00000002957	Nectin3 NCBI RGD Ensembl Show fit	nectin cell adhesion molecule 3
chr5_-_169331163 Show fit	12.20	ENSRNOT00000042301	Espn NCBI RGD Ensembl Show fit	espin
chr11_+_46009322 Show fit	12.09	ENSRNOT00000002233	Tmem45a NCBI RGD Ensembl Show fit	transmembrane protein 45A
chr7_-_49250953 Show fit	11.71	ENSRNOT00000066975 ENSRNOT00000082141	Acss3 NCBI RGD Ensembl Show fit	acyl-CoA synthetase short-chain family member 3
chr14_-_2032593 Show fit	11.67	ENSRNOT00000000037	Fgfrl1 NCBI RGD Ensembl Show fit	fibroblast growth factor receptor-like 1
chr1_-_199377035 Show fit	11.51	ENSRNOT00000026572	Prss8 NCBI RGD Ensembl Show fit	protease, serine, 8
chr10_-_105668593 Show fit	11.46	ENSRNOT00000016622	St6galnac2 NCBI RGD Ensembl Show fit	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr3_-_55822551 Show fit	11.38	ENSRNOT00000082624	Lrp2 NCBI RGD Ensembl Show fit	LDL receptor related protein 2
chr9_+_88357556 Show fit	11.13	ENSRNOT00000020669	Col4a3 NCBI RGD Ensembl Show fit	collagen type IV alpha 3 chain
chr2_+_242882306 Show fit	11.04	ENSRNOT00000013661	Ddit4l NCBI RGD Ensembl Show fit	DNA-damage-inducible transcript 4-like
chr1_+_219233750 Show fit	10.92	ENSRNOT00000024112	Acy3 NCBI RGD Ensembl Show fit	aminoacylase 3
chr7_-_117679219 Show fit	10.91	ENSRNOT00000071522	Slc39a4 NCBI RGD Ensembl Show fit	solute carrier family 39 member 4
chr1_+_178636544 Show fit	10.85	ENSRNOT00000092099	Spon1 NCBI RGD Ensembl Show fit	spondin 1
chr2_+_188543137 Show fit	10.82	ENSRNOT00000027850	Muc1 NCBI RGD Ensembl Show fit	mucin 1, cell surface associated
chr13_-_80775230 Show fit	10.77	ENSRNOT00000091389 ENSRNOT00000004762	Fmo2 NCBI RGD Ensembl Show fit	flavin containing monooxygenase 2
chr2_+_242634399 Show fit	10.76	ENSRNOT00000035700	Emcn NCBI RGD Ensembl Show fit	endomucin
chr1_-_72461547 Show fit	10.45	ENSRNOT00000022480	Ssc5d NCBI RGD Ensembl Show fit	scavenger receptor cysteine rich family member with 5 domains
chr9_+_98073038 Show fit	10.32	ENSRNOT00000026795	Mlph NCBI RGD Ensembl Show fit	melanophilin
chr20_+_41266566 Show fit	10.18	ENSRNOT00000000653	Frk NCBI RGD Ensembl Show fit	fyn-related Src family tyrosine kinase
chr2_+_199162745 Show fit	10.15	ENSRNOT00000023488	Gja5 NCBI RGD Ensembl Show fit	gap junction protein, alpha 5
chr8_+_54925607 Show fit	10.04	ENSRNOT00000059210	Plet1 NCBI RGD Ensembl Show fit	placenta expressed transcript 1
chr11_-_38088753 Show fit	9.83	ENSRNOT00000002713	Tmprss2 NCBI RGD Ensembl Show fit	transmembrane protease, serine 2
chr3_+_109862117 Show fit	9.69	ENSRNOT00000083351 ENSRNOT00000070912	Thbs1 NCBI RGD Ensembl Show fit	thrombospondin 1
chr19_-_25134055 Show fit	9.50	ENSRNOT00000007519	Misp3 NCBI RGD Ensembl Show fit	MISP family member 3
chr6_-_147172022 Show fit	9.31	ENSRNOT00000080675	Itgb8 NCBI RGD Ensembl Show fit	integrin subunit beta 8
chr5_+_58855773 Show fit	9.21	ENSRNOT00000072869	Rusc2 NCBI RGD Ensembl Show fit	RUN and SH3 domain containing 2
chr1_+_78933372 Show fit	9.18	ENSRNOT00000029810	Ccdc8 NCBI RGD Ensembl Show fit	coiled-coil domain containing 8
chr4_+_175431904 Show fit	9.13	ENSRNOT00000032843	Pde3a NCBI RGD Ensembl Show fit	phosphodiesterase 3A
chr5_+_159967839 Show fit	8.88	ENSRNOT00000051317	Hspb7 NCBI RGD Ensembl Show fit	heat shock protein family B (small) member 7
chr5_+_2813131 Show fit	8.87	ENSRNOT00000009530	Sbspon NCBI RGD Ensembl Show fit	somatomedin B and thrombospondin, type 1 domain containing
chr8_-_40078165 Show fit	8.77	ENSRNOT00000014866	Spa17 NCBI RGD Ensembl Show fit	sperm autoantigenic protein 17
chr14_+_86922223 Show fit	8.68	ENSRNOT00000086468	Ramp3 NCBI RGD Ensembl Show fit	receptor activity modifying protein 3
chr9_+_119353840 Show fit	8.67	ENSRNOT00000085362	Myom1 NCBI RGD Ensembl Show fit	myomesin 1
chr14_+_86101277 Show fit	8.62	ENSRNOT00000018846	Aebp1 NCBI RGD Ensembl Show fit	AE binding protein 1
chr7_+_141249044 Show fit	8.58	ENSRNOT00000084911	Aqp5 NCBI RGD Ensembl Show fit	aquaporin 5
chr19_+_52647070 Show fit	8.57	ENSRNOT00000068389 ENSRNOT00000087857	Crispld2 NCBI RGD Ensembl Show fit	cysteine-rich secretory protein LCCL domain containing 2
chr1_+_264504591 Show fit	8.41	ENSRNOT00000050076	Pax2 NCBI RGD Ensembl Show fit	paired box 2
chr6_+_105364668 Show fit	8.29	ENSRNOT00000009513 ENSRNOT00000087090	Ttc9 NCBI RGD Ensembl Show fit	tetratricopeptide repeat domain 9
chr2_+_114423533 Show fit	7.87	ENSRNOT00000091221	Slc2a2 NCBI RGD Ensembl Show fit	solute carrier family 2 member 2
chr9_+_99998275 Show fit	7.74	ENSRNOT00000074395	Gpc1 NCBI RGD Ensembl Show fit	glypican 1
chr8_-_50531423 Show fit	7.67	ENSRNOT00000090985 ENSRNOT00000074942	Apoc3 NCBI RGD Ensembl Show fit	apolipoprotein C3
chr1_+_166433109 Show fit	7.67	ENSRNOT00000026428	Stard10 NCBI RGD Ensembl Show fit	StAR-related lipid transfer domain containing 10
chr9_+_111028824 Show fit	7.58	ENSRNOT00000041418 ENSRNOT00000056457	Pam NCBI RGD Ensembl Show fit	peptidylglycine alpha-amidating monooxygenase
chr2_-_142885604 Show fit	7.56	ENSRNOT00000031487	Frem2 NCBI RGD Ensembl Show fit	Fras1 related extracellular matrix protein 2
chr1_-_189960073 Show fit	7.54	ENSRNOT00000088482	Crym NCBI RGD Ensembl Show fit	crystallin, mu
chr9_+_68414339 Show fit	7.52	ENSRNOT00000040778	Pard3b NCBI RGD Ensembl Show fit	par-3 family cell polarity regulator beta
chr18_+_53609214 Show fit	7.48	ENSRNOT00000077443	Slc27a6 NCBI RGD Ensembl Show fit	solute carrier family 27 member 6
chr8_-_47404010 Show fit	7.39	ENSRNOT00000038647	Tmem136 NCBI RGD Ensembl Show fit	transmembrane protein 136
chr17_+_11953552 Show fit	7.29	ENSRNOT00000090782	Ror2 NCBI RGD Ensembl Show fit	receptor tyrosine kinase-like orphan receptor 2
chr8_+_22189600 Show fit	7.23	ENSRNOT00000061100	Pde4a NCBI RGD Ensembl Show fit	phosphodiesterase 4A
chr10_-_39228090 Show fit	7.21	ENSRNOT00000011340 ENSRNOT00000086644	LOC303140 NCBI RGD Ensembl Show fit	up-regulator of carnitine transporter, OCTN2
chr7_+_126619196 Show fit	7.17	ENSRNOT00000030082	Ppara NCBI RGD Ensembl Show fit	peroxisome proliferator activated receptor alpha
chr5_-_168123030 Show fit	7.10	ENSRNOT00000092747	Per3 NCBI RGD Ensembl Show fit	period circadian clock 3
chr18_-_40716686 Show fit	7.08	ENSRNOT00000000172	Cdo1 NCBI RGD Ensembl Show fit	cysteine dioxygenase type 1
chrX_+_72684329 Show fit	6.93	ENSRNOT00000057644	Dmrtc1c1 NCBI RGD Ensembl Show fit	DMRT-like family C1c1
chr13_+_80125391 Show fit	6.90	ENSRNOT00000044190	Mir199a2 NCBI RGD Ensembl Show fit	microRNA 199a-2
chr1_+_134699299 Show fit	6.88	ENSRNOT00000068766	Rgma NCBI RGD Ensembl Show fit	repulsive guidance molecule family member A
chr16_-_18757918 Show fit	6.86	ENSRNOT00000084172	Sftpd NCBI RGD Ensembl Show fit	surfactant protein D
chr11_+_75434197 Show fit	6.85	ENSRNOT00000032569	Mb21d2 NCBI RGD Ensembl Show fit	Mab-21 domain containing 2
chr6_+_2969333 Show fit	6.84	ENSRNOT00000047356	Morn2 NCBI RGD Ensembl Show fit	MORN repeat containing 2
chr4_+_100166863 Show fit	6.83	ENSRNOT00000014505	Sftpb NCBI RGD Ensembl Show fit	surfactant protein B
chr13_+_75175254 Show fit	6.81	ENSRNOT00000044008	Sec16b NCBI RGD Ensembl Show fit	SEC16 homolog B, endoplasmic reticulum export factor
chr13_-_72890841 Show fit	6.81	ENSRNOT00000093726	RGD1304622 NCBI RGD Ensembl Show fit	similar to 6820428L09 protein
chr15_-_88036354 Show fit	6.80	ENSRNOT00000014747	Ednrb NCBI RGD Ensembl Show fit	endothelin receptor type B
chr1_+_245237736 Show fit	6.76	ENSRNOT00000035814	Vldlr NCBI RGD Ensembl Show fit	very low density lipoprotein receptor
chr2_-_21437193 Show fit	6.75	ENSRNOT00000084002	Ckmt2 NCBI RGD Ensembl Show fit	creatine kinase, mitochondrial 2
chrX_-_37705263 Show fit	6.74	ENSRNOT00000043666	Map3k15 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase kinase kinase 15
chr7_-_120026755 Show fit	6.70	ENSRNOT00000077677	Card10 NCBI RGD Ensembl Show fit	caspase recruitment domain family, member 10
chr1_-_216920625 Show fit	6.69	ENSRNOT00000028119	Osbpl5 NCBI RGD Ensembl Show fit	oxysterol binding protein-like 5
chr1_-_72632185 Show fit	6.66	ENSRNOT00000066383	Tmem190 NCBI RGD Ensembl Show fit	transmembrane protein 190
chr3_+_119015412 Show fit	6.64	ENSRNOT00000013605	Slc27a2 NCBI RGD Ensembl Show fit	solute carrier family 27 member 2
chr16_+_19097391 Show fit	6.61	ENSRNOT00000018018	Calr3 NCBI RGD Ensembl Show fit	calreticulin 3
chr1_+_80321585 Show fit	6.59	ENSRNOT00000022895	Ckm NCBI RGD Ensembl Show fit	creatine kinase, M-type
chr4_-_45332420 Show fit	6.58	ENSRNOT00000083039	Wnt2 NCBI RGD Ensembl Show fit	wingless-type MMTV integration site family member 2
chr6_-_65319527 Show fit	6.58	ENSRNOT00000005618	Stxbp6 NCBI RGD Ensembl Show fit	syntaxin binding protein 6
chr9_-_115382445 Show fit	6.56	ENSRNOT00000091316	Ptprm NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type, M
chr7_-_120027026 Show fit	6.54	ENSRNOT00000011215	Card10 NCBI RGD Ensembl Show fit	caspase recruitment domain family, member 10
chr4_+_121612332 Show fit	6.54	ENSRNOT00000077374 ENSRNOT00000084494	Txnrd3 NCBI RGD Ensembl Show fit	thioredoxin reductase 3
chr6_-_127127413 Show fit	6.53	ENSRNOT00000011906	Prima1 NCBI RGD Ensembl Show fit	proline rich membrane anchor 1
chr11_+_34557679 Show fit	6.53	ENSRNOT00000002289	Ripply3 NCBI RGD Ensembl Show fit	ripply transcriptional repressor 3
chr3_-_156905892 Show fit	6.51	ENSRNOT00000022424	Emilin3 NCBI RGD Ensembl Show fit	elastin microfibril interfacer 3
chr3_-_120106697 Show fit	6.48	ENSRNOT00000020354	Prom2 NCBI RGD Ensembl Show fit	prominin 2
chr5_-_77248563 Show fit	6.44	ENSRNOT00000052243	LOC259245 NCBI RGD Ensembl Show fit	alpha-2u globulin PGCL5
chr3_-_11417546 Show fit	6.43	ENSRNOT00000018776	Lcn2 NCBI RGD Ensembl Show fit	lipocalin 2
chr1_+_101704746 Show fit	6.42	ENSRNOT00000028564	Fam83e NCBI RGD Ensembl Show fit	family with sequence similarity 83, member E
chr1_-_164307084 Show fit	6.40	ENSRNOT00000086091	Serpinh1 NCBI RGD Ensembl Show fit	serpin family H member 1
chrX_+_152999016 Show fit	6.38	ENSRNOT00000088234	Zfp185 NCBI RGD Ensembl Show fit	zinc finger protein 185
chr17_-_56909992 Show fit	6.31	ENSRNOT00000021801	Bambi NCBI RGD Ensembl Show fit	BMP and activin membrane-bound inhibitor
chr6_-_25616995 Show fit	6.29	ENSRNOT00000077894	Fosl2 NCBI RGD Ensembl Show fit	FOS like 2, AP-1 transcription factor subunit
chr10_+_89578212 Show fit	6.28	ENSRNOT00000028178	Arl4d NCBI RGD Ensembl Show fit	ADP-ribosylation factor like GTPase 4D
chr8_+_59278262 Show fit	6.26	ENSRNOT00000017053	Dnaja4 NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member A4
chr10_+_59743544 Show fit	6.21	ENSRNOT00000093497 ENSRNOT00000056460	Tax1bp3 NCBI RGD Ensembl Show fit	Tax1 binding protein 3
chrX_+_152196129 Show fit	6.16	ENSRNOT00000087679	Magea4 NCBI RGD Ensembl Show fit	melanoma antigen, family A, 4
chr10_+_65448950 Show fit	6.13	ENSRNOT00000082348 ENSRNOT00000037016	Rab34 NCBI RGD Ensembl Show fit	RAB34, member RAS oncogene family
chr1_+_81456984 Show fit	6.05	ENSRNOT00000027075	Ethe1 NCBI RGD Ensembl Show fit	ETHE1, persulfide dioxygenase
chr3_+_143172686 Show fit	6.00	ENSRNOT00000006869	Cst9l NCBI RGD Ensembl Show fit	cystatin 9-like
chr5_-_168123395 Show fit	5.94	ENSRNOT00000024932	Per3 NCBI RGD Ensembl Show fit	period circadian clock 3
chr2_-_188672226 Show fit	5.93	ENSRNOT00000027970 ENSRNOT00000050868	Adam15 NCBI RGD Ensembl Show fit	ADAM metallopeptidase domain 15
chr1_-_7480825 Show fit	5.92	ENSRNOT00000048754	Phactr2 NCBI RGD Ensembl Show fit	phosphatase and actin regulator 2
chr1_-_90520012 Show fit	5.89	ENSRNOT00000028698	Kctd15 NCBI RGD Ensembl Show fit	potassium channel tetramerization domain containing 15
chr10_-_98018014 Show fit	5.88	ENSRNOT00000005367	Fam20a NCBI RGD Ensembl Show fit	FAM20A, golgi associated secretory pathway pseudokinase
chr6_+_122920317 Show fit	5.88	ENSRNOT00000068595 ENSRNOT00000082856	Ttc8 NCBI RGD Ensembl Show fit	tetratricopeptide repeat domain 8
chr13_-_86671515 Show fit	5.85	ENSRNOT00000082869	AABR07021704.1 NCBI RGD Ensembl Show fit
chr10_-_91186054 Show fit	5.84	ENSRNOT00000004140	Plcd3 NCBI RGD Ensembl Show fit	phospholipase C, delta 3
chr1_+_236031988 Show fit	5.79	ENSRNOT00000016164	Pcsk5 NCBI RGD Ensembl Show fit	proprotein convertase subtilisin/kexin type 5
chr6_+_26797126 Show fit	5.78	ENSRNOT00000010586	Cgref1 NCBI RGD Ensembl Show fit	cell growth regulator with EF hand domain 1
chrX_+_15035569 Show fit	5.70	ENSRNOT00000006491 ENSRNOT00000078392	Porcn NCBI RGD Ensembl Show fit	porcupine homolog (Drosophila)
chr10_+_49231730 Show fit	5.68	ENSRNOT00000065335	Trim16 NCBI RGD Ensembl Show fit	tripartite motif-containing 16
chr1_+_220446425 Show fit	5.63	ENSRNOT00000027339	LOC100911932 NCBI RGD Ensembl Show fit	endosialin-like
chr20_+_28078500 Show fit	5.61	ENSRNOT00000030005	Ccdc138 NCBI RGD Ensembl Show fit	coiled-coil domain containing 138
chr3_-_160891190 Show fit	5.55	ENSRNOT00000019386	Sdc4 NCBI RGD Ensembl Show fit	syndecan 4
chr12_+_40553741 Show fit	5.51	ENSRNOT00000057396	LOC100360238 NCBI RGD Ensembl Show fit	rCG21419-like
chr18_-_11858744 Show fit	5.49	ENSRNOT00000061417 ENSRNOT00000082891	Dsc2 NCBI RGD Ensembl Show fit	desmocollin 2
chr19_+_23389375 Show fit	5.49	ENSRNOT00000018629	Sall1 NCBI RGD Ensembl Show fit	spalt-like transcription factor 1
chr1_-_90520344 Show fit	5.48	ENSRNOT00000078598	Kctd15 NCBI RGD Ensembl Show fit	potassium channel tetramerization domain containing 15
chr6_-_108596446 Show fit	5.47	ENSRNOT00000031331 ENSRNOT00000077458 ENSRNOT00000082792	Ltbp2 NCBI RGD Ensembl Show fit	latent transforming growth factor beta binding protein 2
chr18_+_47740328 Show fit	5.46	ENSRNOT00000025119	Sncaip NCBI RGD Ensembl Show fit	synuclein, alpha interacting protein
chr7_+_27174882 Show fit	5.42	ENSRNOT00000051181	Glt8d2 NCBI RGD Ensembl Show fit	glycosyltransferase 8 domain containing 2
chr19_-_11302938 Show fit	5.40	ENSRNOT00000038212	AC128848.1 NCBI RGD Ensembl Show fit
chr4_-_120467932 Show fit	5.40	ENSRNOT00000018454	Sec61a1 NCBI RGD Ensembl Show fit	Sec61 translocon alpha 1 subunit
chr1_+_220353356 Show fit	5.39	ENSRNOT00000080189	Cd248 NCBI RGD Ensembl Show fit	CD248 molecule
chr2_+_251863069 Show fit	5.37	ENSRNOT00000036282	Syde2 NCBI RGD Ensembl Show fit	synapse defective Rho GTPase homolog 2
chr1_-_198794947 Show fit	5.36	ENSRNOT00000024639	Znf768 NCBI RGD Ensembl Show fit	zinc finger protein 768
chr6_+_26399950 Show fit	5.32	ENSRNOT00000085424	Ift172 NCBI RGD Ensembl Show fit	intraflagellar transport 172
chr19_+_50246402 Show fit	5.29	ENSRNOT00000018795	Hsd17b2 NCBI RGD Ensembl Show fit	hydroxysteroid (17-beta) dehydrogenase 2
chr8_-_22625959 Show fit	5.26	ENSRNOT00000012138	Yipf2 NCBI RGD Ensembl Show fit	Yip1 domain family, member 2
chr18_+_56364620 Show fit	5.24	ENSRNOT00000068535 ENSRNOT00000086033	Pdgfrb NCBI RGD Ensembl Show fit	platelet derived growth factor receptor beta
chr1_+_82419947 Show fit	5.20	ENSRNOT00000027964	B3gnt8 NCBI RGD Ensembl Show fit	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr13_+_75059927 Show fit	5.17	ENSRNOT00000080801	LOC680254 NCBI RGD Ensembl Show fit	hypothetical protein LOC680254
chr7_+_144052061 Show fit	5.14	ENSRNOT00000020103 ENSRNOT00000091378	Amhr2 NCBI RGD Ensembl Show fit	anti-Mullerian hormone receptor type 2
chr4_+_130172727 Show fit	5.12	ENSRNOT00000051121	Mitf NCBI RGD Ensembl Show fit	melanogenesis associated transcription factor
chr16_-_19097329 Show fit	5.12	ENSRNOT00000030617	RGD1311847 NCBI RGD Ensembl Show fit	similar to 1700030K09Rik protein
chr1_+_266530477 Show fit	5.10	ENSRNOT00000054699	Cnnm2 NCBI RGD Ensembl Show fit	cyclin and CBS domain divalent metal cation transport mediator 2
chr7_-_63578490 Show fit	5.09	ENSRNOT00000007295	Rassf3 NCBI RGD Ensembl Show fit	Ras association domain family member 3
chr11_+_70967439 Show fit	5.05	ENSRNOT00000032518	Iqcg NCBI RGD Ensembl Show fit	IQ motif containing G
chr3_-_94686989 Show fit	5.04	ENSRNOT00000016677	Depdc7 NCBI RGD Ensembl Show fit	DEP domain containing 7
chr5_-_172769421 Show fit	5.03	ENSRNOT00000021285	Prkcz NCBI RGD Ensembl Show fit	protein kinase C, zeta
chr8_-_108777717 Show fit	5.03	ENSRNOT00000034188	Il20rb NCBI RGD Ensembl Show fit	interleukin 20 receptor subunit beta
chr8_-_63350269 Show fit	5.01	ENSRNOT00000042681	Cd276 NCBI RGD Ensembl Show fit	Cd276 molecule
chr6_+_43234526 Show fit	5.01	ENSRNOT00000086808	Asap2 NCBI RGD Ensembl Show fit	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr19_-_58399816 Show fit	5.00	ENSRNOT00000026843	Sipa1l2 NCBI RGD Ensembl Show fit	signal-induced proliferation-associated 1 like 2
chr11_-_61748768 Show fit	4.95	ENSRNOT00000078879	Ccdc191 NCBI RGD Ensembl Show fit	coiled-coil domain containing 191
chr7_+_12619774 Show fit	4.94	ENSRNOT00000015257	Med16 NCBI RGD Ensembl Show fit	mediator complex subunit 16
chr10_-_105771972 Show fit	4.94	ENSRNOT00000074286 ENSRNOT00000066137	Mxra7 NCBI RGD Ensembl Show fit	matrix remodeling associated 7
chr4_-_179700130 Show fit	4.94	ENSRNOT00000021306	Lmntd1 NCBI RGD Ensembl Show fit	lamin tail domain containing 1
chr5_-_77492013 Show fit	4.93	ENSRNOT00000012293	LOC259245 NCBI RGD Ensembl Show fit	alpha-2u globulin PGCL5
chr7_-_51353068 Show fit	4.90	ENSRNOT00000008222	Pawr NCBI RGD Ensembl Show fit	pro-apoptotic WT1 regulator
chr1_+_128924966 Show fit	4.89	ENSRNOT00000019267	Igf1r NCBI RGD Ensembl Show fit	insulin-like growth factor 1 receptor
chr11_-_61748583 Show fit	4.86	ENSRNOT00000093431	Ccdc191 NCBI RGD Ensembl Show fit	coiled-coil domain containing 191
chr6_+_127766470 Show fit	4.82	ENSRNOT00000013138	Serpina5 NCBI RGD Ensembl Show fit	serpin family A member 5
chr15_+_23665202 Show fit	4.80	ENSRNOT00000089226	Samd4a NCBI RGD Ensembl Show fit	sterile alpha motif domain containing 4A
chr13_-_81214494 Show fit	4.77	ENSRNOT00000004950 ENSRNOT00000082385	Prrx1 NCBI RGD Ensembl Show fit	paired related homeobox 1
chr10_+_36099263 Show fit	4.75	ENSRNOT00000083568	Adamts2 NCBI RGD Ensembl Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr3_+_95233874 Show fit	4.74	ENSRNOT00000079743	LOC691083 NCBI RGD Ensembl Show fit	hypothetical protein LOC691083
chr4_+_42202838 Show fit	4.68	ENSRNOT00000082453	Mdfic NCBI RGD Ensembl Show fit	MyoD family inhibitor domain containing
chr2_-_186480278 Show fit	4.68	ENSRNOT00000031743	Kirrel NCBI RGD Ensembl Show fit	kin of IRRE like (Drosophila)
chr6_-_7961207 Show fit	4.67	ENSRNOT00000007174	Abcg5 NCBI RGD Ensembl Show fit	ATP binding cassette subfamily G member 5
chr4_+_44597123 Show fit	4.63	ENSRNOT00000078250	Cav1 NCBI RGD Ensembl Show fit	caveolin 1
chr8_-_65587658 Show fit	4.61	ENSRNOT00000091982	Lrrc49 NCBI RGD Ensembl Show fit	leucine rich repeat containing 49
chr1_+_15642153 Show fit	4.59	ENSRNOT00000079845	Map7 NCBI RGD Ensembl Show fit	microtubule-associated protein 7
chr8_+_116332796 Show fit	4.57	ENSRNOT00000021408	Hyal1 NCBI RGD Ensembl Show fit	hyaluronoglucosaminidase 1
chr10_-_47857326 Show fit	4.57	ENSRNOT00000085703 ENSRNOT00000091963	Epn2 NCBI RGD Ensembl Show fit	epsin 2
chr10_+_63662986 Show fit	4.56	ENSRNOT00000088722	Scarf1 NCBI RGD Ensembl Show fit	scavenger receptor class F, member 1
chr9_+_111649631 Show fit	4.56	ENSRNOT00000056430	Fer NCBI RGD Ensembl Show fit	FER tyrosine kinase
chr19_+_26173771 Show fit	4.55	ENSRNOT00000005581	Fbxw9 NCBI RGD Ensembl Show fit	F-box and WD repeat domain containing 9
chr6_+_137288810 Show fit	4.52	ENSRNOT00000030246	Cep170b NCBI RGD Ensembl Show fit	centrosomal protein 170B
chr10_-_56403188 Show fit	4.48	ENSRNOT00000019947	Chrnb1 NCBI RGD Ensembl Show fit	cholinergic receptor nicotinic beta 1 subunit
chr12_+_19599834 Show fit	4.47	ENSRNOT00000092039 ENSRNOT00000042006	Stag3 NCBI RGD Ensembl Show fit	stromal antigen 3
chr5_-_77342299 Show fit	4.44	ENSRNOT00000075994	RGD1566134 NCBI RGD Ensembl Show fit	similar to alpha-2u-globulin
chr8_+_28352772 Show fit	4.42	ENSRNOT00000012391	Igsf9b NCBI RGD Ensembl Show fit	immunoglobulin superfamily, member 9B
chr6_-_99870024 Show fit	4.41	ENSRNOT00000010043	Rab15 NCBI RGD Ensembl Show fit	RAB15, member RAS oncogene family
chr10_+_55138633 Show fit	4.35	ENSRNOT00000057223	Mfsd6l NCBI RGD Ensembl Show fit	major facilitator superfamily domain containing 6-like
chr1_-_222178725 Show fit	4.35	ENSRNOT00000028697	Esrra NCBI RGD Ensembl Show fit	estrogen related receptor, alpha
chr1_+_65576535 Show fit	4.31	ENSRNOT00000026575	Slc27a5 NCBI RGD Ensembl Show fit	solute carrier family 27 member 5
chr18_-_31071371 Show fit	4.29	ENSRNOT00000060432	Diaph1 NCBI RGD Ensembl Show fit	diaphanous-related formin 1
chr1_-_143535583 Show fit	4.29	ENSRNOT00000087785	Homer2 NCBI RGD Ensembl Show fit	homer scaffolding protein 2
chr1_+_83711251 Show fit	4.25	ENSRNOT00000028237 ENSRNOT00000092008	Cyp2a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily a, polypeptide 1
chr2_+_188844073 Show fit	4.24	ENSRNOT00000028117	Kcnn3 NCBI RGD Ensembl Show fit	potassium calcium-activated channel subfamily N member 3
chr13_-_75059326 Show fit	4.20	ENSRNOT00000089062	Rasal2 NCBI RGD Ensembl Show fit	RAS protein activator like 2
chr14_-_8432195 Show fit	4.18	ENSRNOT00000089800	Arhgap24 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 24
chr7_-_3342491 Show fit	4.17	ENSRNOT00000081756	Rdh5 NCBI RGD Ensembl Show fit	retinol dehydrogenase 5
chr2_+_203200427 Show fit	4.13	ENSRNOT00000020566	Vtcn1 NCBI RGD Ensembl Show fit	V-set domain containing T cell activation inhibitor 1
chr5_-_137372993 Show fit	4.11	ENSRNOT00000092823	Tmem125 NCBI RGD Ensembl Show fit	transmembrane protein 125
chr9_-_15582556 Show fit	4.10	ENSRNOT00000020516	RGD1561662 NCBI RGD Ensembl Show fit	similar to AI661453 protein
chr5_-_77433847 Show fit	4.07	ENSRNOT00000076906 ENSRNOT00000043056	LOC500473 NCBI RGD Ensembl Show fit Mup4 NCBI RGD Ensembl Show fit	similar to alpha-2u globulin PGCL2 major urinary protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.1	15.2	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725)
4.6	13.9	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
3.9	15.5	GO:0016332	establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
3.6	10.9	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
3.4	10.2	GO:0010643	cell communication by chemical coupling(GO:0010643)
3.2	9.7	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
3.0	21.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
2.9	14.7	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
2.8	31.0	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
2.8	8.4	GO:0035566	regulation of metanephros size(GO:0035566)
2.7	13.7	GO:0050828	regulation of liquid surface tension(GO:0050828)
2.7	18.9	GO:0033278	cell proliferation in midbrain(GO:0033278)
2.7	10.8	GO:0072592	oxygen metabolic process(GO:0072592)
2.7	18.8	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
2.6	10.5	GO:0042494	detection of bacterial lipoprotein(GO:0042494)
2.6	7.7	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
2.6	10.3	GO:0014826	vein smooth muscle contraction(GO:0014826)
2.6	7.7	GO:0010982	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) regulation of high-density lipoprotein particle clearance(GO:0010982)
2.4	2.4	GO:0071579	regulation of zinc ion transport(GO:0071579)
2.4	7.1	GO:0042412	taurine biosynthetic process(GO:0042412)
2.2	11.1	GO:0048550	negative regulation of pinocytosis(GO:0048550)
2.2	6.6	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
2.1	6.4	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
2.0	9.9	GO:0009758	carbohydrate utilization(GO:0009758)
2.0	5.9	GO:0048560	establishment of anatomical structure orientation(GO:0048560)
1.9	3.9	GO:0007172	signal complex assembly(GO:0007172)
1.9	7.6	GO:0031179	peptide modification(GO:0031179)
1.8	5.5	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
1.8	9.1	GO:0060282	positive regulation of oocyte development(GO:0060282)
1.8	7.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
1.8	7.2	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
1.7	12.2	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
1.7	6.8	GO:0034436	glycoprotein transport(GO:0034436)
1.7	5.0	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
1.7	5.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
1.6	4.9	GO:0043133	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of neuronal action potential(GO:1904457)
1.6	4.9	GO:1904193	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
1.6	3.2	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
1.5	13.9	GO:0070995	NADPH oxidation(GO:0070995)
1.5	6.1	GO:0070813	hydrogen sulfide metabolic process(GO:0070813)
1.5	1.5	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
1.4	5.6	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887) positive regulation of extracellular exosome assembly(GO:1903553)
1.4	12.3	GO:1902414	protein localization to cell junction(GO:1902414)
1.4	4.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
1.4	10.8	GO:0090240	negative regulation of cell adhesion mediated by integrin(GO:0033629) positive regulation of histone H4 acetylation(GO:0090240)
1.3	4.0	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.3	5.2	GO:0072277	cell migration involved in vasculogenesis(GO:0035441) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.3	3.8	GO:0046078	dUMP metabolic process(GO:0046078)
1.3	3.8	GO:0072156	distal tubule morphogenesis(GO:0072156)
1.2	8.7	GO:0002074	extraocular skeletal muscle development(GO:0002074)
1.2	8.6	GO:0015670	carbon dioxide transport(GO:0015670)
1.2	3.6	GO:0016107	sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
1.2	4.8	GO:0061107	seminal vesicle development(GO:0061107)
1.2	3.6	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
1.2	5.9	GO:0044691	tooth eruption(GO:0044691)
1.2	2.4	GO:0046379	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
1.2	3.5	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
1.1	4.6	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.1	4.6	GO:0050904	Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
1.1	12.4	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
1.1	3.4	GO:0051695	actin filament uncapping(GO:0051695)
1.1	3.4	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.1	8.9	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
1.1	3.3	GO:1901873	regulation of post-translational protein modification(GO:1901873)
1.1	4.4	GO:1902606	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
1.1	5.4	GO:0039019	pronephric nephron development(GO:0039019)
1.1	4.3	GO:0046951	ketone body biosynthetic process(GO:0046951)
1.1	11.7	GO:0060539	diaphragm development(GO:0060539)
1.1	3.2	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
1.0	3.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
1.0	5.2	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.0	6.1	GO:0044351	macropinocytosis(GO:0044351)
1.0	5.0	GO:2000664	positive regulation of T-helper 2 cell cytokine production(GO:2000553) positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
1.0	3.0	GO:0006114	glycerol biosynthetic process(GO:0006114)
1.0	6.9	GO:0009804	coumarin metabolic process(GO:0009804)
1.0	5.8	GO:0002001	renin secretion into blood stream(GO:0002001)
0.9	4.7	GO:0030300	regulation of intestinal cholesterol absorption(GO:0030300)
0.9	5.7	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.9	11.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.9	9.8	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.9	5.1	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.8	2.5	GO:0021577	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) response to methamphetamine hydrochloride(GO:1904313)
0.8	2.4	GO:0006083	acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
0.8	2.4	GO:0006574	valine catabolic process(GO:0006574)
0.8	4.0	GO:0033026	negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.8	6.4	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.8	1.6	GO:0002930	trabecular meshwork development(GO:0002930)
0.8	6.3	GO:0001661	conditioned taste aversion(GO:0001661)
0.8	5.5	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.8	9.4	GO:0086103	G-protein coupled receptor signaling pathway involved in heart process(GO:0086103)
0.8	13.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.8	3.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.8	3.8	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.8	2.3	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.8	6.8	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.8	2.3	GO:0060490	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.7	11.5	GO:0070633	transepithelial transport(GO:0070633)
0.7	7.2	GO:0060033	anatomical structure regression(GO:0060033)
0.7	2.9	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.7	4.9	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.7	1.4	GO:0038183	bile acid signaling pathway(GO:0038183)
0.7	4.1	GO:0072602	interleukin-4 secretion(GO:0072602)
0.7	7.5	GO:0070327	thyroid hormone transport(GO:0070327)
0.7	2.0	GO:0098749	cerebellar neuron development(GO:0098749)
0.7	10.2	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.7	11.4	GO:0045056	transcytosis(GO:0045056)
0.7	5.3	GO:0061525	hindgut development(GO:0061525)
0.7	9.3	GO:0001573	ganglioside metabolic process(GO:0001573)
0.7	7.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.7	2.0	GO:0051012	microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.6	2.6	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6	8.9	GO:0015693	magnesium ion transport(GO:0015693)
0.6	6.3	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.6	8.8	GO:0051601	exocyst localization(GO:0051601)
0.6	3.7	GO:0072675	osteoclast fusion(GO:0072675)
0.6	6.5	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.6	5.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.6	1.7	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.5	1.1	GO:0046066	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.5	6.5	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.5	1.6	GO:0006788	heme oxidation(GO:0006788)
0.5	11.5	GO:0097503	sialylation(GO:0097503)
0.5	1.6	GO:1990401	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling(GO:0060683) embryonic lung development(GO:1990401)
0.5	3.5	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.5	5.5	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.5	6.4	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.5	3.4	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.5	2.4	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.5	14.2	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313)
0.5	1.4	GO:0071934	thiamine transmembrane transport(GO:0071934)
0.5	6.4	GO:0007288	sperm axoneme assembly(GO:0007288)
0.5	5.0	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.5	3.2	GO:0046959	habituation(GO:0046959)
0.5	3.2	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.4	4.5	GO:0035095	behavioral response to nicotine(GO:0035095)
0.4	1.3	GO:0006589	octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.4	2.2	GO:0001579	medium-chain fatty acid transport(GO:0001579)
0.4	4.8	GO:0048664	neuron fate determination(GO:0048664)
0.4	10.3	GO:0032400	melanosome localization(GO:0032400)
0.4	2.5	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.4	3.3	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.4	14.2	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.4	0.8	GO:0033092	positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.4	1.9	GO:0001552	ovarian follicle atresia(GO:0001552)
0.4	1.1	GO:0046356	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.4	1.1	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.4	10.8	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.4	1.4	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.3	14.5	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.3	5.8	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.3	2.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	1.4	GO:1904975	response to bleomycin(GO:1904975)
0.3	8.4	GO:0010842	retina layer formation(GO:0010842)
0.3	2.3	GO:0000103	sulfate assimilation(GO:0000103)
0.3	1.3	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.3	1.0	GO:1901526	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3	1.6	GO:0001582	detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
0.3	4.3	GO:0071420	cellular response to histamine(GO:0071420)
0.3	1.4	GO:0000706	meiotic DNA double-strand break processing(GO:0000706)
0.3	3.2	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.3	3.4	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.3	1.7	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.3	4.4	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.3	6.5	GO:0060037	pharyngeal system development(GO:0060037)
0.3	1.1	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.3	2.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.3	3.4	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3	1.6	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.3	8.8	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.3	7.1	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.3	4.3	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.2	4.6	GO:0033327	Leydig cell differentiation(GO:0033327)
0.2	10.3	GO:0006749	glutathione metabolic process(GO:0006749)
0.2	2.9	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.2	0.9	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.2	1.4	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2	0.7	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.2	0.9	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.2	2.4	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2	4.8	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2	0.6	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2	3.9	GO:0006828	manganese ion transport(GO:0006828)
0.2	2.8	GO:0031507	heterochromatin assembly(GO:0031507)
0.2	1.8	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.2	1.0	GO:0006102	isocitrate metabolic process(GO:0006102)
0.2	3.9	GO:0002385	organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.2	4.3	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.2	2.1	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.2	1.6	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2	0.4	GO:0030186	melatonin metabolic process(GO:0030186)
0.2	0.4	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2	2.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.2	1.0	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.2	2.8	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.2	1.5	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.2	2.3	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.2	4.9	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.2	0.5	GO:2001034	histone H3-K36 dimethylation(GO:0097676) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1	1.7	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	3.2	GO:0097435	fibril organization(GO:0097435)
0.1	4.8	GO:0030199	collagen fibril organization(GO:0030199)
0.1	1.8	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	0.3	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.1	1.6	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1	5.3	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	3.5	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1	1.4	GO:0033622	integrin activation(GO:0033622)
0.1	0.7	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.1	0.9	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	4.9	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580)
0.1	3.9	GO:0033627	cell adhesion mediated by integrin(GO:0033627)
0.1	0.6	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1	5.9	GO:0015914	phospholipid transport(GO:0015914)
0.1	4.4	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.1	0.9	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	7.4	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.1	0.6	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.1	2.2	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1	1.0	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.1	4.5	GO:0007129	synapsis(GO:0007129)
0.1	2.3	GO:0044030	regulation of DNA methylation(GO:0044030)
0.1	0.1	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1	1.7	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	2.1	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.1	1.5	GO:0043248	proteasome assembly(GO:0043248)
0.1	1.4	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	1.0	GO:0097264	self proteolysis(GO:0097264)
0.1	0.8	GO:0015732	prostaglandin transport(GO:0015732)
0.1	0.3	GO:0015684	ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.1	2.3	GO:1901998	toxin transport(GO:1901998)
0.1	1.0	GO:0045116	protein neddylation(GO:0045116)
0.1	0.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1	1.8	GO:0019730	antimicrobial humoral response(GO:0019730)
0.1	7.1	GO:0009408	response to heat(GO:0009408)
0.1	3.1	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.1	1.4	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1	1.4	GO:0035864	response to potassium ion(GO:0035864)
0.1	2.0	GO:0007032	endosome organization(GO:0007032)
0.1	2.4	GO:0048662	negative regulation of smooth muscle cell proliferation(GO:0048662)
0.1	6.1	GO:0006457	protein folding(GO:0006457)
0.1	3.9	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1	0.3	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973) regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0	4.1	GO:0006497	protein lipidation(GO:0006497)
0.0	3.9	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0	0.4	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.0	3.9	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.0	0.4	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.1	GO:0033386	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0	1.3	GO:1904377	positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.7	GO:0042304	regulation of fatty acid biosynthetic process(GO:0042304)
0.0	0.6	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.0	0.7	GO:0009251	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0	1.2	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.0	2.6	GO:0001676	long-chain fatty acid metabolic process(GO:0001676)
0.0	0.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.3	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	1.4	GO:0070206	protein trimerization(GO:0070206)
0.0	0.1	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0	1.0	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	0.8	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.3	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.3	GO:0042574	retinal metabolic process(GO:0042574)
0.0	2.0	GO:0006694	steroid biosynthetic process(GO:0006694)
0.0	0.5	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.3	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	1.2	GO:0009062	fatty acid catabolic process(GO:0009062)
0.0	0.2	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.7	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.7	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	1.7	GO:0046546	male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0	0.5	GO:1902652	cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.5	GO:0007422	peripheral nervous system development(GO:0007422)
0.0	0.0	GO:0051461	negative regulation of histone deacetylation(GO:0031064) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	9.3	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
2.5	7.6	GO:0000802	transverse filament(GO:0000802)
2.5	17.7	GO:1990357	terminal web(GO:1990357)
2.0	13.9	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
1.7	6.7	GO:0002079	inner acrosomal membrane(GO:0002079)
1.6	6.5	GO:0071914	microspike(GO:0044393) prominosome(GO:0071914)
1.5	9.2	GO:1990393	3M complex(GO:1990393)
1.5	4.6	GO:0036117	hyaluranon cable(GO:0036117)
1.4	11.1	GO:0098645	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
1.3	7.7	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
1.2	4.9	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
1.2	9.7	GO:0005577	fibrinogen complex(GO:0005577)
1.2	16.5	GO:0032426	stereocilium tip(GO:0032426)
1.1	10.3	GO:0016461	unconventional myosin complex(GO:0016461)
1.1	21.1	GO:0031528	microvillus membrane(GO:0031528)
0.9	3.8	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.9	12.8	GO:0032433	filopodium tip(GO:0032433)
0.9	5.3	GO:0097598	sperm cytoplasmic droplet(GO:0097598)
0.8	2.4	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.6	5.0	GO:0043203	axon hillock(GO:0043203)
0.6	6.2	GO:0034464	BBSome(GO:0034464)
0.6	8.7	GO:0043202	lysosomal lumen(GO:0043202)
0.6	7.7	GO:0046581	intercellular canaliculus(GO:0046581)
0.6	2.9	GO:0045252	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) oxoglutarate dehydrogenase complex(GO:0045252)
0.6	8.8	GO:0035686	sperm fibrous sheath(GO:0035686)
0.6	6.4	GO:0002177	manchette(GO:0002177)
0.6	5.8	GO:1990635	proximal dendrite(GO:1990635)
0.6	5.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6	3.9	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.5	6.8	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.5	6.8	GO:0097208	alveolar lamellar body(GO:0097208)
0.5	43.9	GO:0044291	cell-cell contact zone(GO:0044291)
0.4	8.0	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.4	2.8	GO:0031094	platelet dense tubular network(GO:0031094)
0.4	2.0	GO:0070695	FHF complex(GO:0070695)
0.4	8.7	GO:0031430	M band(GO:0031430)
0.4	17.4	GO:0016459	myosin complex(GO:0016459)
0.4	4.0	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.4	5.7	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3	23.8	GO:0005581	collagen trimer(GO:0005581)
0.3	3.4	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.3	14.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.3	3.5	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3	2.8	GO:0005677	chromatin silencing complex(GO:0005677)
0.3	1.6	GO:1903767	sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
0.3	18.3	GO:0031225	anchored component of membrane(GO:0031225)
0.3	1.2	GO:0072487	MSL complex(GO:0072487)
0.3	1.7	GO:0005608	laminin-3 complex(GO:0005608)
0.3	5.6	GO:0043034	costamere(GO:0043034)
0.3	12.9	GO:0009925	basal plasma membrane(GO:0009925)
0.3	19.3	GO:0031526	brush border membrane(GO:0031526)
0.3	3.5	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3	6.7	GO:0034451	centriolar satellite(GO:0034451)
0.3	0.8	GO:1902560	GMP reductase complex(GO:1902560)
0.3	6.6	GO:0000145	exocyst(GO:0000145)
0.3	12.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.2	1.7	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2	3.9	GO:0030061	mitochondrial crista(GO:0030061)
0.2	6.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.2	2.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.2	2.7	GO:0030008	TRAPP complex(GO:0030008)
0.2	4.5	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.2	4.0	GO:0005614	interstitial matrix(GO:0005614)
0.2	0.6	GO:1990462	omegasome membrane(GO:1903349) omegasome(GO:1990462)
0.2	1.4	GO:0001651	dense fibrillar component(GO:0001651)
0.2	1.4	GO:0031105	septin complex(GO:0031105) sperm annulus(GO:0097227)
0.2	1.5	GO:0031931	TORC1 complex(GO:0031931)
0.2	2.0	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2	50.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.2	0.7	GO:0000938	GARP complex(GO:0000938) EARP complex(GO:1990745)
0.2	1.5	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	2.8	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	9.1	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	1.5	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	6.1	GO:0045171	intercellular bridge(GO:0045171)
0.1	6.9	GO:0015030	Cajal body(GO:0015030)
0.1	3.6	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	0.7	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.6	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	5.6	GO:0016592	mediator complex(GO:0016592)
0.1	2.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	2.0	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	6.6	GO:0031594	neuromuscular junction(GO:0031594)
0.1	1.6	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	4.3	GO:0005903	brush border(GO:0005903)
0.1	3.2	GO:0035869	ciliary transition zone(GO:0035869)
0.1	0.4	GO:0097165	nuclear stress granule(GO:0097165)
0.1	0.5	GO:0033268	node of Ranvier(GO:0033268)
0.1	1.7	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.7	GO:0031595	nuclear proteasome complex(GO:0031595)
0.1	25.0	GO:0016324	apical plasma membrane(GO:0016324)
0.1	6.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	12.2	GO:0001650	fibrillar center(GO:0001650)
0.1	3.0	GO:0005902	microvillus(GO:0005902)
0.1	1.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	4.1	GO:0005884	actin filament(GO:0005884)
0.1	5.7	GO:0030018	Z disc(GO:0030018)
0.1	11.1	GO:0005770	late endosome(GO:0005770)
0.1	7.3	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	0.7	GO:0042555	MCM complex(GO:0042555)
0.1	1.4	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1	0.9	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	3.1	GO:0030175	filopodium(GO:0030175)
0.0	7.4	GO:0031012	extracellular matrix(GO:0031012)
0.0	2.1	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	3.0	GO:0045095	keratin filament(GO:0045095)
0.0	0.3	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.7	GO:0032420	stereocilium(GO:0032420)
0.0	0.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	2.0	GO:0030016	myofibril(GO:0030016)
0.0	7.5	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	0.5	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	1.2	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	16.2	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	2.0	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.9	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.2	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	2.4	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.5	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	21.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
3.6	10.9	GO:0004046	aminoacylase activity(GO:0004046)
3.5	17.4	GO:0070052	collagen V binding(GO:0070052)
2.6	5.1	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
2.6	7.7	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
2.5	10.2	GO:0086077	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
2.3	6.8	GO:0034437	glycoprotein transporter activity(GO:0034437)
2.1	24.7	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
2.0	20.3	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
2.0	11.7	GO:0042954	lipoprotein transporter activity(GO:0042954)
1.9	7.6	GO:0016842	amidine-lyase activity(GO:0016842)
1.7	5.2	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
1.6	7.9	GO:0005550	pheromone binding(GO:0005550)
1.5	11.7	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
1.4	6.9	GO:0050501	hyaluronan synthase activity(GO:0050501)
1.3	4.0	GO:0033823	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.3	3.9	GO:0042015	interleukin-20 binding(GO:0042015)
1.2	8.6	GO:0004111	creatine kinase activity(GO:0004111)
1.2	3.6	GO:0045550	geranylgeranyl reductase activity(GO:0045550)
1.2	4.8	GO:0032190	acrosin binding(GO:0032190)
1.2	3.6	GO:0035939	microsatellite binding(GO:0035939)
1.2	3.5	GO:0004956	prostaglandin D receptor activity(GO:0004956)
1.2	3.5	GO:0031708	endothelin B receptor binding(GO:0031708)
1.1	23.7	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
1.1	3.3	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
1.0	5.2	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.0	29.2	GO:0017147	Wnt-protein binding(GO:0017147)
1.0	5.0	GO:0004962	endothelin receptor activity(GO:0004962)
1.0	15.6	GO:0015026	coreceptor activity(GO:0015026)
0.9	7.9	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.8	3.3	GO:0050610	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.8	23.7	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.8	2.3	GO:0004779	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.8	2.3	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.8	13.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.8	5.3	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.7	2.2	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.7	2.2	GO:0016414	carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
0.7	6.6	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.7	6.5	GO:0043495	protein anchor(GO:0043495)
0.7	5.7	GO:0051525	NFAT protein binding(GO:0051525)
0.7	31.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.7	18.5	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.6	5.7	GO:0019966	interleukin-1 binding(GO:0019966)
0.6	7.5	GO:0070324	thyroid hormone binding(GO:0070324)
0.6	6.3	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.6	3.7	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.6	8.6	GO:0015250	water channel activity(GO:0015250)
0.6	2.4	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.6	4.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.6	4.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.6	1.7	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.6	3.9	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.6	4.4	GO:0004966	galanin receptor activity(GO:0004966)
0.5	4.9	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.5	4.9	GO:0043559	insulin binding(GO:0043559)
0.5	1.6	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.5	3.2	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.5	3.7	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.5	4.7	GO:0030957	Tat protein binding(GO:0030957)
0.5	1.5	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.5	3.0	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.5	11.5	GO:0008373	sialyltransferase activity(GO:0008373)
0.5	16.0	GO:0001968	fibronectin binding(GO:0001968)
0.5	4.7	GO:0017127	cholesterol transporter activity(GO:0017127)
0.5	1.4	GO:0015234	thiamine transmembrane transporter activity(GO:0015234)
0.5	6.6	GO:0051787	misfolded protein binding(GO:0051787)
0.5	6.5	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.5	15.3	GO:0005109	frizzled binding(GO:0005109)
0.5	5.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.5	6.8	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.4	1.3	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.4	8.9	GO:0031005	filamin binding(GO:0031005)
0.4	10.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4	2.4	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.4	3.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.4	1.6	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.4	8.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.4	6.9	GO:0017160	Ral GTPase binding(GO:0017160)
0.4	1.5	GO:0001156	TFIIIC-class transcription factor binding(GO:0001156)
0.4	1.1	GO:0044715	8-oxo-dGDP phosphatase activity(GO:0044715)
0.4	3.9	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4	4.6	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.4	4.6	GO:0045295	gamma-catenin binding(GO:0045295)
0.3	1.4	GO:0005499	vitamin D binding(GO:0005499) bile acid receptor activity(GO:0038181) vitamin D response element binding(GO:0070644)
0.3	3.8	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.3	3.4	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.3	4.6	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.3	1.0	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
0.3	3.9	GO:0008432	JUN kinase binding(GO:0008432)
0.3	8.7	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3	2.3	GO:0008430	selenium binding(GO:0008430)
0.3	13.2	GO:0015485	cholesterol binding(GO:0015485)
0.3	6.6	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3	2.4	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3	2.1	GO:0004065	arylsulfatase activity(GO:0004065)
0.3	12.6	GO:0001784	phosphotyrosine binding(GO:0001784)
0.3	5.8	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.3	1.4	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.3	1.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.3	4.8	GO:0005522	profilin binding(GO:0005522)
0.3	0.8	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3	4.5	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.3	7.6	GO:0030371	translation repressor activity(GO:0030371)
0.3	6.9	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.3	4.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.3	2.5	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3	1.3	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.2	3.0	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.2	3.0	GO:0004000	adenosine deaminase activity(GO:0004000)
0.2	6.6	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.2	3.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.2	3.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	4.0	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.2	1.4	GO:0030274	LIM domain binding(GO:0030274)
0.2	5.9	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.2	0.2	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2	2.0	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.2	3.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.2	3.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.2	4.3	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.2	3.5	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2	0.7	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	2.9	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	4.3	GO:0071837	HMG box domain binding(GO:0071837)
0.2	11.0	GO:0051082	unfolded protein binding(GO:0051082)
0.2	5.3	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.2	1.0	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2	0.9	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2	1.6	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	2.0	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2	1.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	2.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	12.3	GO:0008013	beta-catenin binding(GO:0008013)
0.1	2.1	GO:0097602	cullin family protein binding(GO:0097602)
0.1	0.7	GO:0071253	connexin binding(GO:0071253)
0.1	1.7	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	2.5	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.1	6.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	3.9	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.9	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	1.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	1.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.9	GO:0016421	CoA carboxylase activity(GO:0016421)
0.1	10.6	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	0.7	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.1	1.6	GO:0016805	dipeptidase activity(GO:0016805)
0.1	1.3	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	18.9	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	8.1	GO:0002039	p53 binding(GO:0002039)
0.1	6.5	GO:0048029	monosaccharide binding(GO:0048029)
0.1	1.6	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	1.4	GO:0003796	lysozyme activity(GO:0003796)
0.1	0.6	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	11.5	GO:0008201	heparin binding(GO:0008201)
0.1	0.7	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	2.4	GO:0005158	insulin receptor binding(GO:0005158)
0.1	0.3	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1	0.4	GO:0034452	dynactin binding(GO:0034452)
0.1	4.9	GO:0043621	protein self-association(GO:0043621)
0.1	1.6	GO:0008199	ferric iron binding(GO:0008199)
0.1	7.7	GO:0002020	protease binding(GO:0002020)
0.1	3.4	GO:0005496	steroid binding(GO:0005496)
0.1	3.9	GO:0043022	ribosome binding(GO:0043022)
0.1	3.4	GO:0051018	protein kinase A binding(GO:0051018)
0.1	2.6	GO:0070888	E-box binding(GO:0070888)
0.1	12.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	0.9	GO:0051378	serotonin binding(GO:0051378)
0.1	5.6	GO:0017124	SH3 domain binding(GO:0017124)
0.1	4.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.7	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	2.3	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.5	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	4.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	11.3	GO:0045296	cadherin binding(GO:0045296)
0.0	1.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.4	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	2.3	GO:0030674	protein binding, bridging(GO:0030674)
0.0	0.5	GO:0031402	sodium ion binding(GO:0031402)
0.0	1.1	GO:0030145	manganese ion binding(GO:0030145)
0.0	1.5	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	6.0	GO:0016757	transferase activity, transferring glycosyl groups(GO:0016757)
0.0	4.8	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.1	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0	3.3	GO:0005179	hormone activity(GO:0005179)
0.0	0.8	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.4	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.7	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	2.4	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	80.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.5	13.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.5	9.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5	10.7	PID NECTIN PATHWAY	Nectin adhesion pathway
0.4	1.7	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.4	6.8	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.4	20.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.4	7.7	ST G ALPHA S PATHWAY	G alpha s Pathway
0.4	14.7	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.4	21.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.3	4.6	PID ALK2 PATHWAY	ALK2 signaling events
0.3	64.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.3	9.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.3	3.9	PID EPO PATHWAY	EPO signaling pathway
0.3	12.7	PID BMP PATHWAY	BMP receptor signaling
0.3	4.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.3	14.0	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.3	21.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.3	11.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.2	0.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	6.8	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.2	56.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	2.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.2	1.6	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.2	10.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.2	8.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2	4.2	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.2	2.3	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.1	7.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	3.0	PID ENDOTHELIN PATHWAY	Endothelins
0.1	2.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	5.3	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	1.0	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	2.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	2.2	PID BARD1 PATHWAY	BARD1 signaling events
0.1	0.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	1.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.7	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.0	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.8	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	23.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
1.0	5.8	REACTOME SIGNALLING BY NGF	Genes involved in Signalling by NGF
0.9	10.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.9	17.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.9	16.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.8	11.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.7	8.6	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.7	5.4	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.6	10.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.6	15.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.6	10.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.5	4.6	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.5	22.8	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.5	11.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.5	28.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.5	7.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.5	6.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.5	13.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.4	4.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.4	2.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.4	2.9	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.3	4.0	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.3	1.3	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.3	3.9	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.3	23.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.3	4.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3	4.7	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.3	3.8	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.3	26.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.3	4.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.3	7.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	3.9	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	2.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2	2.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	2.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.2	20.4	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2	3.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	2.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	17.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	2.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.8	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	2.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.1	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	2.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	0.5	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.1	1.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	4.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	3.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	2.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	1.6	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	5.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	3.3	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	0.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	1.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.9	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	3.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	1.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	1.0	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	2.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	0.8	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	7.1	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.9	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.9	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	2.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.8	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.9	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	2.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.6	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	1.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.6	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation

Results for Tfap2a

Z-value: 0.98

Motif logo

Transcription factors associated with Tfap2a

Activity-expression correlation:

Activity profile of Tfap2a motif

Sorted Z-values of Tfap2a motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: