ISMARA results: Ubp1

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Ubp1

Z-value: 0.88

Motif logo

Transcription factors associated with Ubp1

Gene Symbol	Gene ID	Gene Info
Ubp1 NCBI RGD Ensembl	ENSRNOG00000009729	upstream binding protein 1 (LBP-1a)

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Ubp1	rn6_v1_chr8_+_122197027_122197027	0.26	2.7e-06	Click!

Activity profile of Ubp1 motif

Sorted Z-values of Ubp1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_+_98457810 Show fit	28.96	ENSRNOT00000074175	AABR07060872.1 NCBI RGD Ensembl Show fit
chr7_+_120153184 Show fit	22.81	ENSRNOT00000013538	Lgals1 NCBI RGD Ensembl Show fit	galectin 1
chr4_+_98370797 Show fit	21.27	ENSRNOT00000031991	AABR07060872.1 NCBI RGD Ensembl Show fit
chr2_+_223029559 Show fit	20.56	ENSRNOT00000045584	AABR07013111.1 NCBI RGD Ensembl Show fit
chr11_+_86092468 Show fit	20.43	ENSRNOT00000057971	LOC100361706 NCBI RGD Ensembl Show fit	lambda-chain C1-region-like
chrX_+_28539158 Show fit	19.16	ENSRNOT00000073535	Tlr8 NCBI RGD Ensembl Show fit	toll-like receptor 8
chr3_+_19274273 Show fit	18.19	ENSRNOT00000040102	AABR07051684.1 NCBI RGD Ensembl Show fit
chr4_+_106323089 Show fit	17.38	ENSRNOT00000091402	AABR07061134.1 NCBI RGD Ensembl Show fit
chr1_-_227441442 Show fit	17.12	ENSRNOT00000028433	Ms4a1 NCBI RGD Ensembl Show fit	membrane spanning 4-domains A1
chr3_-_2853272 Show fit	16.62	ENSRNOT00000023022	Fcna NCBI RGD Ensembl Show fit	ficolin A
chr6_-_138508753 Show fit	16.41	ENSRNOT00000006888	Ighm NCBI RGD Ensembl Show fit	immunoglobulin heavy constant mu
chr4_+_69403735 Show fit	15.96	ENSRNOT00000082012	Trbv13-1 NCBI RGD Ensembl Show fit	T cell receptor beta, variable 13-1
chr4_+_14151343 Show fit	15.90	ENSRNOT00000061687 ENSRNOT00000076573 ENSRNOT00000077219 ENSRNOT00000008319	Cd36 NCBI RGD Ensembl Show fit	CD36 molecule
chr3_-_17081510 Show fit	15.78	ENSRNOT00000063862	AABR07051562.1 NCBI RGD Ensembl Show fit
chr3_-_16752353 Show fit	15.37	ENSRNOT00000046489	AABR07051548.1 NCBI RGD Ensembl Show fit
chr4_-_103258134 Show fit	14.05	ENSRNOT00000086827	AABR07061052.1 NCBI RGD Ensembl Show fit
chr6_-_125723944 Show fit	13.83	ENSRNOT00000007004	Fbln5 NCBI RGD Ensembl Show fit	fibulin 5
chr3_+_17107861 Show fit	13.56	ENSRNOT00000043097	AABR07051563.1 NCBI RGD Ensembl Show fit
chr15_+_57241968 Show fit	13.39	ENSRNOT00000082191	Lcp1 NCBI RGD Ensembl Show fit	lymphocyte cytosolic protein 1
chr10_+_45258887 Show fit	13.36	ENSRNOT00000048642	Btnl10 NCBI RGD Ensembl Show fit	butyrophilin like 10
chr4_+_70828894 Show fit	12.73	ENSRNOT00000064892	Trbc2 NCBI RGD Ensembl Show fit	T cell receptor beta, constant 2
chr6_-_142060032 Show fit	12.62	ENSRNOT00000064717	AABR07065811.1 NCBI RGD Ensembl Show fit
chr5_+_173288447 Show fit	12.24	ENSRNOT00000091205 ENSRNOT00000067252	Mxra8 NCBI RGD Ensembl Show fit	matrix remodeling associated 8
chr3_+_17139670 Show fit	12.16	ENSRNOT00000073316	AABR07051564.1 NCBI RGD Ensembl Show fit
chr4_-_98305173 Show fit	11.71	ENSRNOT00000010151	Il23r NCBI RGD Ensembl Show fit	interleukin 23 receptor
chr3_+_19174027 Show fit	11.60	ENSRNOT00000074445	AABR07051678.1 NCBI RGD Ensembl Show fit
chr2_-_60683451 Show fit	11.06	ENSRNOT00000046215	Rai14 NCBI RGD Ensembl Show fit	retinoic acid induced 14
chr8_+_49282460 Show fit	11.05	ENSRNOT00000021488	Cd3d NCBI RGD Ensembl Show fit	CD3d molecule
chr1_+_199555722 Show fit	10.90	ENSRNOT00000054983	Itgax NCBI RGD Ensembl Show fit	integrin subunit alpha X
chr5_+_144308611 Show fit	10.80	ENSRNOT00000014388	Col8a2 NCBI RGD Ensembl Show fit	collagen type VIII alpha 2 chain
chr20_-_32353677 Show fit	10.65	ENSRNOT00000035355	Stox1 NCBI RGD Ensembl Show fit	storkhead box 1
chr8_+_55603968 Show fit	10.58	ENSRNOT00000066848	Pou2af1 NCBI RGD Ensembl Show fit	POU class 2 associating factor 1
chr3_+_20375699 Show fit	10.58	ENSRNOT00000088492	AABR07051731.1 NCBI RGD Ensembl Show fit
chr6_-_143195143 Show fit	10.53	ENSRNOT00000081337	AABR07065837.1 NCBI RGD Ensembl Show fit
chr6_-_125723732 Show fit	10.43	ENSRNOT00000084815	Fbln5 NCBI RGD Ensembl Show fit	fibulin 5
chr6_-_142993147 Show fit	10.36	ENSRNOT00000044381	LOC100359978 NCBI RGD Ensembl Show fit	mCG1038839-like
chr1_-_73682247 Show fit	10.23	ENSRNOT00000079498	Lilra5 NCBI RGD Ensembl Show fit	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr3_+_17180411 Show fit	10.20	ENSRNOT00000058260	AABR07051565.1 NCBI RGD Ensembl Show fit
chr7_-_18793289 Show fit	10.11	ENSRNOT00000036375	AABR07056026.1 NCBI RGD Ensembl Show fit
chr8_-_125544427 Show fit	10.02	ENSRNOT00000041548 ENSRNOT00000039904 ENSRNOT00000036642	Rbms3 NCBI RGD Ensembl Show fit	RNA binding motif, single stranded interacting protein 3
chr3_-_14643897 Show fit	9.92	ENSRNOT00000082008 ENSRNOT00000025983	Ggta1 NCBI RGD Ensembl Show fit	glycoprotein, alpha-galactosyltransferase 1
chr3_-_110517163 Show fit	9.70	ENSRNOT00000078037	Plcb2 NCBI RGD Ensembl Show fit	phospholipase C, beta 2
chr5_-_79691258 Show fit	9.56	ENSRNOT00000072920	Tnfsf8 NCBI RGD Ensembl Show fit	tumor necrosis factor superfamily member 8
chr9_-_14668297 Show fit	9.52	ENSRNOT00000042404	Treml2 NCBI RGD Ensembl Show fit	triggering receptor expressed on myeloid cells-like 2
chr6_-_141488290 Show fit	9.31	ENSRNOT00000067336	AABR07065792.1 NCBI RGD Ensembl Show fit
chr12_+_19714324 Show fit	9.30	ENSRNOT00000072303	RGD1559588 NCBI RGD Ensembl Show fit	similar to cell surface receptor FDFACT
chr19_-_10976396 Show fit	9.25	ENSRNOT00000073239	Nlrc5 NCBI RGD Ensembl Show fit	NLR family, CARD domain containing 5
chr3_+_16817051 Show fit	9.09	ENSRNOT00000071666	AABR07051550.1 NCBI RGD Ensembl Show fit
chr4_+_14109864 Show fit	9.06	ENSRNOT00000076349	RGD1565355 NCBI RGD Ensembl Show fit	similar to fatty acid translocase/CD36
chr6_-_139997537 Show fit	9.06	ENSRNOT00000073207	AABR07065740.1 NCBI RGD Ensembl Show fit
chr3_-_20695952 Show fit	9.01	ENSRNOT00000072306	AABR07051746.1 NCBI RGD Ensembl Show fit
chr15_-_34603819 Show fit	8.91	ENSRNOT00000067539	Cma1 NCBI RGD Ensembl Show fit	chymase 1
chr17_+_15814132 Show fit	8.87	ENSRNOT00000032997	Susd3 NCBI RGD Ensembl Show fit	sushi domain containing 3
chr4_-_163227242 Show fit	8.83	ENSRNOT00000091552 ENSRNOT00000077793	Clec7a NCBI RGD Ensembl Show fit	C-type lectin domain family 7, member A
chr3_-_20479999 Show fit	8.81	ENSRNOT00000050573	AABR07051733.2 NCBI RGD Ensembl Show fit
chr12_-_20486276 Show fit	8.80	ENSRNOT00000074057	LOC680910 NCBI RGD Ensembl Show fit	similar to paired immunoglobin-like type 2 receptor beta
chr12_+_25498198 Show fit	8.68	ENSRNOT00000076916	Ncf1 NCBI RGD Ensembl Show fit	neutrophil cytosolic factor 1
chr10_-_56506446 Show fit	8.53	ENSRNOT00000021357	Acap1 NCBI RGD Ensembl Show fit	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr3_+_19441604 Show fit	8.48	ENSRNOT00000090581	AABR07051692.1 NCBI RGD Ensembl Show fit
chr4_+_90990088 Show fit	8.39	ENSRNOT00000030320	Mmrn1 NCBI RGD Ensembl Show fit	multimerin 1
chr14_-_17225389 Show fit	8.30	ENSRNOT00000052035	Art3 NCBI RGD Ensembl Show fit	ADP-ribosyltransferase 3
chr4_+_144192989 Show fit	8.22	ENSRNOT00000007523	Lmcd1 NCBI RGD Ensembl Show fit	LIM and cysteine-rich domains 1
chr3_+_16495748 Show fit	8.19	ENSRNOT00000045492	AABR07051533.1 NCBI RGD Ensembl Show fit
chrX_-_1346181 Show fit	8.19	ENSRNOT00000042736	LOC102555453 NCBI RGD Ensembl Show fit	60S ribosomal protein L12-like
chr12_+_48577905 Show fit	8.17	ENSRNOT00000000888	Selplg NCBI RGD Ensembl Show fit	selectin P ligand
chr6_-_142372031 Show fit	8.09	ENSRNOT00000063929	AABR07065814.3 NCBI RGD Ensembl Show fit
chr9_+_92618352 Show fit	8.02	ENSRNOT00000034603	Sp140 NCBI RGD Ensembl Show fit	SP140 nuclear body protein
chr4_-_70996395 Show fit	8.00	ENSRNOT00000021485	Kel NCBI RGD Ensembl Show fit	Kell blood group, metallo-endopeptidase
chr6_-_140880070 Show fit	7.99	ENSRNOT00000073779	LOC691828 NCBI RGD Ensembl Show fit	uncharacterized LOC691828
chr8_-_63092009 Show fit	7.97	ENSRNOT00000034300	Loxl1 NCBI RGD Ensembl Show fit	lysyl oxidase-like 1
chr1_+_47231093 Show fit	7.91	ENSRNOT00000024967	Sytl3 NCBI RGD Ensembl Show fit	synaptotagmin-like 3
chr4_+_179398621 Show fit	7.87	ENSRNOT00000049474 ENSRNOT00000067506	Lrmp NCBI RGD Ensembl Show fit	lymphoid-restricted membrane protein
chr1_-_101236065 Show fit	7.86	ENSRNOT00000066834	Cd37 NCBI RGD Ensembl Show fit	CD37 molecule
chr6_-_140642221 Show fit	7.86	ENSRNOT00000081996	AABR07065772.2 NCBI RGD Ensembl Show fit
chr3_-_20419417 Show fit	7.84	ENSRNOT00000077772	AABR07051733.3 NCBI RGD Ensembl Show fit
chr10_-_63491279 Show fit	7.65	ENSRNOT00000082301	Tusc5 NCBI RGD Ensembl Show fit	tumor suppressor candidate 5
chr1_-_213650247 Show fit	7.64	ENSRNOT00000019679	Cox8b NCBI RGD Ensembl Show fit	cytochrome c oxidase, subunit VIIIb
chr10_+_12046701 Show fit	7.59	ENSRNOT00000011073 ENSRNOT00000084004	Mefv NCBI RGD Ensembl Show fit	MEFV, pyrin innate immunity regulator
chr8_+_117694605 Show fit	7.57	ENSRNOT00000027994	Col7a1 NCBI RGD Ensembl Show fit	collagen type VII alpha 1 chain
chr5_+_133865331 Show fit	7.56	ENSRNOT00000035409	Tal1 NCBI RGD Ensembl Show fit	TAL bHLH transcription factor 1, erythroid differentiation factor
chr15_-_34612432 Show fit	7.53	ENSRNOT00000090206	Mcpt1l1 NCBI RGD Ensembl Show fit	mast cell protease 1-like 1
chr6_-_75874235 Show fit	7.46	ENSRNOT00000009080	Baz1a NCBI RGD Ensembl Show fit	bromodomain adjacent to zinc finger domain, 1A
chr19_+_24456976 Show fit	7.45	ENSRNOT00000004900	Ucp1 NCBI RGD Ensembl Show fit	uncoupling protein 1
chr2_-_149325913 Show fit	7.45	ENSRNOT00000036690	Gpr171 NCBI RGD Ensembl Show fit	G protein-coupled receptor 171
chr4_+_101909389 Show fit	7.43	ENSRNOT00000086458	AABR07060963.2 NCBI RGD Ensembl Show fit
chr7_-_29152442 Show fit	7.42	ENSRNOT00000079774	Mybpc1 NCBI RGD Ensembl Show fit	myosin binding protein C, slow type
chr14_-_18849258 Show fit	7.40	ENSRNOT00000033406	Pf4 NCBI RGD Ensembl Show fit	platelet factor 4
chr17_-_54808483 Show fit	7.32	ENSRNOT00000075683	AABR07028049.1 NCBI RGD Ensembl Show fit
chr11_+_17538063 Show fit	7.23	ENSRNOT00000031889 ENSRNOT00000090878	Chodl NCBI RGD Ensembl Show fit	chondrolectin
chr16_-_48437223 Show fit	7.17	ENSRNOT00000013005 ENSRNOT00000059401	Enpp6 NCBI RGD Ensembl Show fit	ectonucleotide pyrophosphatase/phosphodiesterase 6
chr8_-_133128290 Show fit	7.15	ENSRNOT00000008783	Ccr1l1 NCBI RGD Ensembl Show fit	chemokine (C-C motif) receptor 1-like 1
chr7_+_144623555 Show fit	7.13	ENSRNOT00000022217	Hoxc6 NCBI RGD Ensembl Show fit	homeo box C6
chr4_-_145390447 Show fit	6.96	ENSRNOT00000091965 ENSRNOT00000012136	Cidec NCBI RGD Ensembl Show fit	cell death-inducing DFFA-like effector c
chrX_-_105390580 Show fit	6.94	ENSRNOT00000077547	Btk NCBI RGD Ensembl Show fit	Bruton tyrosine kinase
chr6_-_141062581 Show fit	6.94	ENSRNOT00000073446	AABR07065778.3 NCBI RGD Ensembl Show fit
chr6_-_143131118 Show fit	6.90	ENSRNOT00000074930	AABR07065834.1 NCBI RGD Ensembl Show fit
chr1_+_168957460 Show fit	6.87	ENSRNOT00000090745	LOC103694857 NCBI RGD Ensembl Show fit	hemoglobin subunit beta-2
chr10_+_45893018 Show fit	6.79	ENSRNOT00000004280 ENSRNOT00000086710	Nlrp3 NCBI RGD Ensembl Show fit	NLR family, pyrin domain containing 3
chr4_-_156276304 Show fit	6.78	ENSRNOT00000078725	Clec4e NCBI RGD Ensembl Show fit	C-type lectin domain family 4, member E
chr6_-_140485913 Show fit	6.76	ENSRNOT00000048463	AABR07065768.1 NCBI RGD Ensembl Show fit
chr19_-_39267928 Show fit	6.68	ENSRNOT00000027686	Tmed6 NCBI RGD Ensembl Show fit	transmembrane p24 trafficking protein 6
chr10_-_75171774 Show fit	6.64	ENSRNOT00000011735	Epx NCBI RGD Ensembl Show fit	eosinophil peroxidase
chr15_+_32817343 Show fit	6.64	ENSRNOT00000073853	AABR07017902.1 NCBI RGD Ensembl Show fit
chr12_-_21362205 Show fit	6.52	ENSRNOT00000064787	LOC108348155 NCBI RGD Ensembl Show fit	paired immunoglobulin-like type 2 receptor beta-2
chr4_+_44597123 Show fit	6.49	ENSRNOT00000078250	Cav1 NCBI RGD Ensembl Show fit	caveolin 1
chr9_+_67774150 Show fit	6.48	ENSRNOT00000091060	Icos NCBI RGD Ensembl Show fit	inducible T-cell co-stimulator
chr4_+_78694447 Show fit	6.44	ENSRNOT00000011945	Gpnmb NCBI RGD Ensembl Show fit	glycoprotein nmb
chr12_-_21670269 Show fit	6.43	ENSRNOT00000074863	LOC100910801 NCBI RGD Ensembl Show fit	paired immunoglobulin-like type 2 receptor alpha-like
chr14_-_72122158 Show fit	6.33	ENSRNOT00000064495	C1qtnf7 NCBI RGD Ensembl Show fit	C1q and tumor necrosis factor related protein 7
chr7_-_12424367 Show fit	6.32	ENSRNOT00000060698	Midn NCBI RGD Ensembl Show fit	midnolin
chr20_-_3374344 Show fit	6.30	ENSRNOT00000082999	Ppp1r18 NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory subunit 18
chr10_+_88326337 Show fit	6.30	ENSRNOT00000022029 ENSRNOT00000076461	Fkbp10 NCBI RGD Ensembl Show fit	FK506 binding protein 10
chr6_-_138640187 Show fit	6.28	ENSRNOT00000087983	AABR07065651.6 NCBI RGD Ensembl Show fit
chr15_+_57221292 Show fit	6.26	ENSRNOT00000014502	Lcp1 NCBI RGD Ensembl Show fit	lymphocyte cytosolic protein 1
chr4_+_69457472 Show fit	6.26	ENSRNOT00000067597	Trbv19 NCBI RGD Ensembl Show fit	T cell receptor beta, variable 19
chr4_+_14070553 Show fit	6.25	ENSRNOT00000077505	Cd36 NCBI RGD Ensembl Show fit	CD36 molecule
chrX_+_71174699 Show fit	6.20	ENSRNOT00000076957 ENSRNOT00000090192 ENSRNOT00000040334	Med12 NCBI RGD Ensembl Show fit	mediator complex subunit 12
chr10_-_87067456 Show fit	6.20	ENSRNOT00000014163	Ccr7 NCBI RGD Ensembl Show fit	C-C motif chemokine receptor 7
chr1_-_175796040 Show fit	6.10	ENSRNOT00000024060	Mrvi1 NCBI RGD Ensembl Show fit	murine retrovirus integration site 1 homolog
chr6_-_122239614 Show fit	6.04	ENSRNOT00000005015	Galc NCBI RGD Ensembl Show fit	galactosylceramidase
chr18_-_55859333 Show fit	6.02	ENSRNOT00000025989	Myoz3 NCBI RGD Ensembl Show fit	myozenin 3
chr6_-_138772736 Show fit	6.01	ENSRNOT00000071492	AABR07065651.1 NCBI RGD Ensembl Show fit
chr1_+_84304228 Show fit	5.90	ENSRNOT00000024771	Prx NCBI RGD Ensembl Show fit	periaxin
chr8_+_67753279 Show fit	5.89	ENSRNOT00000009716	Calml4 NCBI RGD Ensembl Show fit	calmodulin-like 4
chr1_-_127337882 Show fit	5.88	ENSRNOT00000085158	Aldh1a3 NCBI RGD Ensembl Show fit	aldehyde dehydrogenase 1 family, member A3
chr10_+_75087892 Show fit	5.76	ENSRNOT00000065910	Mpo NCBI RGD Ensembl Show fit	myeloperoxidase
chr1_-_89045586 Show fit	5.75	ENSRNOT00000063808	Zbtb32 NCBI RGD Ensembl Show fit	zinc finger and BTB domain containing 32
chr12_-_16126953 Show fit	5.72	ENSRNOT00000001682	Lfng NCBI RGD Ensembl Show fit	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr20_+_5040337 Show fit	5.71	ENSRNOT00000068435	Clic1 NCBI RGD Ensembl Show fit	chloride intracellular channel 1
chr2_-_186515135 Show fit	5.61	ENSRNOT00000077375	Kirrel NCBI RGD Ensembl Show fit	kin of IRRE like (Drosophila)
chr3_-_166994286 Show fit	5.60	ENSRNOT00000081593	Zfp217 NCBI RGD Ensembl Show fit	zinc finger protein 217
chr6_-_33738825 Show fit	5.57	ENSRNOT00000039492	Slc7a15 NCBI RGD Ensembl Show fit	solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chr7_+_143060597 Show fit	5.57	ENSRNOT00000087481	Krt7 NCBI RGD Ensembl Show fit	keratin 7
chrX_+_75382598 Show fit	5.54	ENSRNOT00000033494	Uprt NCBI RGD Ensembl Show fit	uracil phosphoribosyltransferase homolog
chr2_+_208749996 Show fit	5.54	ENSRNOT00000086321	Chia NCBI RGD Ensembl Show fit	chitinase, acidic
chr6_-_141008427 Show fit	5.52	ENSRNOT00000074472	AABR07065778.2 NCBI RGD Ensembl Show fit
chrX_-_157331204 Show fit	5.50	ENSRNOT00000085201	Bgn NCBI RGD Ensembl Show fit	biglycan
chr17_-_79676499 Show fit	5.45	ENSRNOT00000022711	Itga8 NCBI RGD Ensembl Show fit	integrin subunit alpha 8
chrX_-_138435391 Show fit	5.43	ENSRNOT00000043258	Mbnl3 NCBI RGD Ensembl Show fit	muscleblind-like splicing regulator 3
chr6_+_93281408 Show fit	5.41	ENSRNOT00000009610	Frmd6 NCBI RGD Ensembl Show fit	FERM domain containing 6
chr17_-_43614844 Show fit	5.32	ENSRNOT00000023054	Hist1h1a NCBI RGD Ensembl Show fit	histone cluster 1 H1 family member a
chr1_-_174495258 Show fit	5.31	ENSRNOT00000052377 ENSRNOT00000086349	Scube2 NCBI RGD Ensembl Show fit	signal peptide, CUB domain and EGF like domain containing 2
chr4_-_165192647 Show fit	5.31	ENSRNOT00000086461	Klra5 NCBI RGD Ensembl Show fit	killer cell lectin-like receptor, subfamily A, member 5
chr19_+_61332351 Show fit	5.29	ENSRNOT00000014492	Nrp1 NCBI RGD Ensembl Show fit	neuropilin 1
chr1_-_8751198 Show fit	5.23	ENSRNOT00000030511	Adgrg6 NCBI RGD Ensembl Show fit	adhesion G protein-coupled receptor G6
chr1_-_47307488 Show fit	5.23	ENSRNOT00000090033	Ezr NCBI RGD Ensembl Show fit	ezrin
chr3_-_146470293 Show fit	5.17	ENSRNOT00000009627	Acss1 NCBI RGD Ensembl Show fit	acyl-CoA synthetase short-chain family member 1
chr6_-_140418831 Show fit	5.16	ENSRNOT00000086301	AABR07065768.2 NCBI RGD Ensembl Show fit
chr17_+_90696019 Show fit	5.11	ENSRNOT00000003438	Gpr137b NCBI RGD Ensembl Show fit	G protein-coupled receptor 137B
chr4_-_78342863 Show fit	5.11	ENSRNOT00000049038	Gimap6 NCBI RGD Ensembl Show fit	GTPase, IMAP family member 6
chr3_-_119611136 Show fit	5.03	ENSRNOT00000016157	Ncaph NCBI RGD Ensembl Show fit	non-SMC condensin I complex, subunit H
chr17_-_9762813 Show fit	4.97	ENSRNOT00000033749	Slc34a1 NCBI RGD Ensembl Show fit	solute carrier family 34 member 1
chr1_+_81230612 Show fit	4.96	ENSRNOT00000026489	Kcnn4 NCBI RGD Ensembl Show fit	potassium calcium-activated channel subfamily N member 4
chr12_+_19680712 Show fit	4.93	ENSRNOT00000081310	AABR07035561.2 NCBI RGD Ensembl Show fit
chr6_-_140266507 Show fit	4.92	ENSRNOT00000082865	AABR07065753.1 NCBI RGD Ensembl Show fit
chr6_+_24163026 Show fit	4.92	ENSRNOT00000061284	Lbh NCBI RGD Ensembl Show fit	limb bud and heart development
chr3_+_112242270 Show fit	4.92	ENSRNOT00000080533 ENSRNOT00000082876	Capn3 NCBI RGD Ensembl Show fit	calpain 3
chr1_-_169534896 Show fit	4.92	ENSRNOT00000082645	Trim30c NCBI RGD Ensembl Show fit	tripartite motif-containing 30C
chr3_+_18787606 Show fit	4.90	ENSRNOT00000090508	AABR07051658.1 NCBI RGD Ensembl Show fit
chr20_-_5227620 Show fit	4.87	ENSRNOT00000086240	RT1-DMb NCBI RGD Ensembl Show fit	RT1 class II, locus DMb
chr11_+_60383431 Show fit	4.86	ENSRNOT00000093295	Cd200 NCBI RGD Ensembl Show fit	Cd200 molecule
chr8_-_116045954 Show fit	4.84	ENSRNOT00000020065	Mapkapk3 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase-activated protein kinase 3
chr8_+_118392773 Show fit	4.82	ENSRNOT00000066305	LOC100911725 NCBI RGD Ensembl Show fit	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4-like
chr1_+_32221636 Show fit	4.82	ENSRNOT00000022346 ENSRNOT00000089941	Slc6a18 NCBI RGD Ensembl Show fit	solute carrier family 6 member 18
chr13_+_89826254 Show fit	4.81	ENSRNOT00000006141	F11r NCBI RGD Ensembl Show fit	F11 receptor
chr1_+_140601791 Show fit	4.78	ENSRNOT00000091588	Isg20 NCBI RGD Ensembl Show fit	interferon stimulated exonuclease gene 20
chr4_-_123713319 Show fit	4.78	ENSRNOT00000012875 ENSRNOT00000086982	Slc6a6 NCBI RGD Ensembl Show fit	solute carrier family 6 member 6
chr19_-_37448067 Show fit	4.75	ENSRNOT00000092844	Zdhhc1 NCBI RGD Ensembl Show fit	zinc finger, DHHC-type containing 1
chr19_-_55300403 Show fit	4.74	ENSRNOT00000018591	Rnf166 NCBI RGD Ensembl Show fit	ring finger protein 166
chr1_+_216293087 Show fit	4.74	ENSRNOT00000027875 ENSRNOT00000087153	Kcnq1 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily Q member 1
chr7_+_114997103 Show fit	4.73	ENSRNOT00000010224	Ptp4a3 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase type IVA, member 3
chr6_-_142299996 Show fit	4.73	ENSRNOT00000086580	Ighv8-2 NCBI RGD Ensembl Show fit	immunoglobulin heavy variable V8-2
chr5_+_118541979 Show fit	4.69	ENSRNOT00000013089	Efcab7 NCBI RGD Ensembl Show fit	EF-hand calcium binding domain 7
chr2_+_198388809 Show fit	4.68	ENSRNOT00000083087	Hist2h2aa3 NCBI RGD Ensembl Show fit	histone cluster 2, H2aa3
chr4_-_149988295 Show fit	4.62	ENSRNOT00000019649	Fxyd4 NCBI RGD Ensembl Show fit	FXYD domain-containing ion transport regulator 4
chr17_-_89163113 Show fit	4.61	ENSRNOT00000050445	LOC100360843 NCBI RGD Ensembl Show fit	ribosomal protein S19-like
chr10_+_56193856 Show fit	4.59	ENSRNOT00000080584 ENSRNOT00000091216 ENSRNOT00000083458	Tp53 NCBI RGD Ensembl Show fit	tumor protein p53
chr10_+_29165577 Show fit	4.57	ENSRNOT00000078415	Ccnjl NCBI RGD Ensembl Show fit	cyclin J-like
chr10_-_4257868 Show fit	4.56	ENSRNOT00000035886	Tnfrsf17 NCBI RGD Ensembl Show fit	TNF receptor superfamily member 17
chr13_+_50103189 Show fit	4.56	ENSRNOT00000004078	Atp2b4 NCBI RGD Ensembl Show fit	ATPase plasma membrane Ca2+ transporting 4
chr13_+_88995316 Show fit	4.56	ENSRNOT00000004117	Olfml2b NCBI RGD Ensembl Show fit	olfactomedin-like 2B
chr3_-_20050486 Show fit	4.55	ENSRNOT00000088887	AABR07051718.1 NCBI RGD Ensembl Show fit
chr12_-_6879154 Show fit	4.51	ENSRNOT00000001207	Alox5ap NCBI RGD Ensembl Show fit	arachidonate 5-lipoxygenase activating protein
chr1_-_101086198 Show fit	4.45	ENSRNOT00000027917	Rcn3 NCBI RGD Ensembl Show fit	reticulocalbin 3
chr12_-_9990284 Show fit	4.43	ENSRNOT00000001264	Rasl11a NCBI RGD Ensembl Show fit	RAS-like family 11 member A
chr16_-_47207487 Show fit	4.41	ENSRNOT00000059459	Dctd NCBI RGD Ensembl Show fit	dCMP deaminase
chr5_-_118541928 Show fit	4.40	ENSRNOT00000012947	Itgb3bp NCBI RGD Ensembl Show fit	integrin subunit beta 3 binding protein
chr3_+_148541909 Show fit	4.39	ENSRNOT00000012187	Ccm2l NCBI RGD Ensembl Show fit	CCM2 like scaffolding protein
chr8_-_112884062 Show fit	4.37	ENSRNOT00000016222 ENSRNOT00000085585	Acpp NCBI RGD Ensembl Show fit	acid phosphatase, prostate
chr11_-_64853692 Show fit	4.34	ENSRNOT00000002089	Cd80 NCBI RGD Ensembl Show fit	Cd80 molecule
chr20_+_1809078 Show fit	4.34	ENSRNOT00000084853	Olr1739 NCBI RGD Ensembl Show fit	olfactory receptor 1739
chr10_-_89088993 Show fit	4.34	ENSRNOT00000027458	Ccr10 NCBI RGD Ensembl Show fit	C-C motif chemokine receptor 10
chr6_-_30187337 Show fit	4.28	ENSRNOT00000074150	Itsn2 NCBI RGD Ensembl Show fit	intersectin 2
chr11_-_38088753 Show fit	4.28	ENSRNOT00000002713	Tmprss2 NCBI RGD Ensembl Show fit	transmembrane protease, serine 2
chr5_+_104698040 Show fit	4.27	ENSRNOT00000009127	Adamtsl1 NCBI RGD Ensembl Show fit	ADAMTS-like 1
chr1_+_157701089 Show fit	4.24	ENSRNOT00000014271	Prcp NCBI RGD Ensembl Show fit	prolylcarboxypeptidase
chr8_-_132189388 Show fit	4.22	ENSRNOT00000005817	Zdhhc3 NCBI RGD Ensembl Show fit	zinc finger, DHHC-type containing 3
chr6_+_50528823 Show fit	4.21	ENSRNOT00000008321	Lamb1 NCBI RGD Ensembl Show fit	laminin subunit beta 1
chr10_+_17261541 Show fit	4.21	ENSRNOT00000005478	Sh3pxd2b NCBI RGD Ensembl Show fit	SH3 and PX domains 2B
chr17_+_78879058 Show fit	4.20	ENSRNOT00000022043	Olah NCBI RGD Ensembl Show fit	oleoyl-ACP hydrolase

Network of associatons between targets according to the STRING database.

First level regulatory network of Ubp1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.4	19.2	GO:2001183	negative regulation of interleukin-12 secretion(GO:2001183)
4.3	21.6	GO:0002317	plasma cell differentiation(GO:0002317)
4.2	16.6	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
3.9	15.8	GO:0071226	cellular response to molecule of fungal origin(GO:0071226)
3.7	22.2	GO:2000334	blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
3.7	11.0	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
3.4	3.4	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
3.3	9.9	GO:0042125	protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
3.2	9.6	GO:0070946	neutrophil mediated killing of gram-positive bacterium(GO:0070946)
3.1	12.2	GO:0060857	establishment of glial blood-brain barrier(GO:0060857)
2.5	7.6	GO:0045799	positive regulation of chromatin assembly or disassembly(GO:0045799)
2.4	24.3	GO:0048251	elastic fiber assembly(GO:0048251)
2.3	9.2	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
2.2	6.5	GO:2000286	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) regulation of inward rectifier potassium channel activity(GO:1901979) positive regulation of gap junction assembly(GO:1903598) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
2.1	6.2	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
2.0	5.9	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
2.0	7.9	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
2.0	5.9	GO:0060166	olfactory pit development(GO:0060166)
1.9	5.8	GO:0002148	hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
1.9	7.6	GO:0071640	regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
1.8	7.4	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
1.8	5.4	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
1.8	5.4	GO:0002215	defense response to nematode(GO:0002215)
1.8	3.5	GO:1903849	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
1.8	5.3	GO:1904835	vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
1.7	5.2	GO:1902965	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
1.7	5.2	GO:0019541	acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
1.7	6.8	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713) positive regulation of T-helper 17 type immune response(GO:2000318)
1.7	5.0	GO:2000118	dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
1.6	4.9	GO:1990091	sodium-dependent self proteolysis(GO:1990091)
1.6	4.8	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
1.5	3.1	GO:0032752	regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
1.5	10.6	GO:0071500	cellular response to nitrosative stress(GO:0071500)
1.5	4.6	GO:0045763	regulation of arginine metabolic process(GO:0000821) negative regulation of cellular amino acid metabolic process(GO:0045763)
1.5	4.4	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
1.5	4.4	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
1.4	5.7	GO:0007386	compartment pattern specification(GO:0007386)
1.4	4.2	GO:0002353	kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
1.4	4.2	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.4	4.1	GO:0036486	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
1.3	4.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
1.3	8.0	GO:0031133	cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133)
1.3	6.3	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
1.3	3.8	GO:0042891	antibiotic transport(GO:0042891)
1.2	9.9	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
1.2	4.9	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
1.2	6.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
1.2	3.5	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
1.1	4.6	GO:1904024	negative regulation of fermentation(GO:1901003) negative regulation of NAD metabolic process(GO:1902689) negative regulation of glucose catabolic process to lactate via pyruvate(GO:1904024)
1.1	4.5	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
1.1	6.7	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
1.1	5.5	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.1	4.4	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.1	23.5	GO:0071803	positive regulation of podosome assembly(GO:0071803)
1.1	5.3	GO:1902732	positive regulation of chondrocyte proliferation(GO:1902732)
1.1	3.2	GO:2000612	thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
1.0	5.0	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.9	2.8	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.9	5.4	GO:0003383	apical constriction(GO:0003383)
0.9	2.6	GO:0006649	phospholipid transfer to membrane(GO:0006649)
0.8	4.2	GO:1904179	positive regulation of adipose tissue development(GO:1904179)
0.8	11.7	GO:0002827	positive regulation of T-helper 1 type immune response(GO:0002827)
0.8	3.3	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.8	4.9	GO:1904674	positive regulation of somatic stem cell population maintenance(GO:1904674)
0.8	11.3	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.8	9.6	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.8	5.5	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.8	4.7	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.8	11.0	GO:0045059	positive thymic T cell selection(GO:0045059)
0.8	2.3	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.7	7.4	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.7	2.2	GO:0048210	Golgi vesicle fusion to target membrane(GO:0048210)
0.7	2.9	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.7	7.2	GO:0019695	choline metabolic process(GO:0019695)
0.7	9.9	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
0.7	8.4	GO:0046541	saliva secretion(GO:0046541)
0.7	5.5	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.6	10.8	GO:0031295	T cell costimulation(GO:0031295)
0.6	2.5	GO:0031179	peptide modification(GO:0031179)
0.6	2.5	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.6	3.8	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.6	7.4	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.6	6.1	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.6	4.8	GO:0044351	macropinocytosis(GO:0044351)
0.6	3.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.6	4.2	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.6	6.6	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.6	1.8	GO:0040009	regulation of growth rate(GO:0040009)
0.6	2.3	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.6	7.4	GO:0002024	diet induced thermogenesis(GO:0002024)
0.5	4.9	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.5	2.6	GO:1901656	glycoside transport(GO:1901656)
0.5	1.5	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.5	3.6	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.5	2.0	GO:0009597	detection of virus(GO:0009597)
0.5	5.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.5	1.5	GO:0032218	riboflavin transport(GO:0032218)
0.5	2.9	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.5	1.0	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
0.5	3.9	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.5	2.4	GO:1904177	regulation of adipose tissue development(GO:1904177)
0.5	3.9	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.5	4.3	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.5	1.4	GO:0002333	transitional stage B cell differentiation(GO:0002332) transitional one stage B cell differentiation(GO:0002333) positive regulation of actin filament binding(GO:1904531) positive regulation of actin binding(GO:1904618)
0.5	1.9	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) protein K29-linked ubiquitination(GO:0035519)
0.5	7.0	GO:0034389	lipid particle organization(GO:0034389)
0.5	2.3	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.5	6.9	GO:0015671	oxygen transport(GO:0015671)
0.5	1.4	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.4	3.5	GO:0097461	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.4	3.5	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4	1.7	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.4	7.2	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.4	0.4	GO:0043132	NAD transport(GO:0043132)
0.4	5.8	GO:0060347	heart trabecula formation(GO:0060347)
0.4	6.9	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.4	1.2	GO:0018343	protein farnesylation(GO:0018343)
0.4	2.4	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.4	2.0	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.4	9.7	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.4	3.5	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.4	1.9	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.4	5.7	GO:0043486	histone exchange(GO:0043486)
0.4	4.8	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4	1.8	GO:1904717	regulation of AMPA glutamate receptor clustering(GO:1904717)
0.4	2.6	GO:0043615	astrocyte cell migration(GO:0043615)
0.4	2.2	GO:0010587	miRNA catabolic process(GO:0010587)
0.4	1.1	GO:0002143	tRNA wobble position uridine thiolation(GO:0002143)
0.4	3.2	GO:0099638	endosome to plasma membrane protein transport(GO:0099638)
0.4	2.1	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3	9.4	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.3	1.3	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.3	1.0	GO:1902499	positive regulation of protein autoubiquitination(GO:1902499)
0.3	1.6	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3	1.0	GO:0046380	N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
0.3	2.2	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.3	1.9	GO:0015074	DNA integration(GO:0015074)
0.3	1.5	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.3	1.8	GO:0034059	response to anoxia(GO:0034059)
0.3	1.5	GO:0010819	regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820)
0.3	1.2	GO:0010446	response to alkaline pH(GO:0010446)
0.3	11.6	GO:0050798	activated T cell proliferation(GO:0050798)
0.3	1.9	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.3	6.6	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.3	0.8	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.3	2.2	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.3	9.0	GO:0018345	protein palmitoylation(GO:0018345)
0.3	2.4	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.3	1.8	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3	6.4	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.3	3.8	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
0.3	1.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.2	1.0	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.2	0.7	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.2	1.9	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2	2.7	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.2	1.3	GO:2000819	regulation of nucleotide-excision repair(GO:2000819)
0.2	2.5	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.2	2.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2	3.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.2	0.8	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.2	1.4	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2	3.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2	4.4	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.2	0.6	GO:1901367	response to L-cysteine(GO:1901367)
0.2	9.3	GO:0035904	aorta development(GO:0035904)
0.2	5.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	0.2	GO:0036334	epidermal stem cell homeostasis(GO:0036334)
0.2	2.7	GO:0006910	phagocytosis, recognition(GO:0006910)
0.2	1.1	GO:0090367	negative regulation of mRNA modification(GO:0090367)
0.2	1.4	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.2	1.6	GO:2000210	positive regulation of anoikis(GO:2000210)
0.2	1.0	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.2	2.8	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2	7.6	GO:0035987	endodermal cell differentiation(GO:0035987)
0.2	2.9	GO:0048266	behavioral response to pain(GO:0048266)
0.2	1.3	GO:0001927	exocyst assembly(GO:0001927)
0.2	4.4	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.2	2.9	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.2	2.4	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.2	0.6	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2	6.5	GO:0015804	neutral amino acid transport(GO:0015804)
0.2	6.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	2.2	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.1	0.4	GO:0071221	response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1	0.3	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1	2.4	GO:0006152	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.1	3.2	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.1	1.0	GO:0060346	bone trabecula formation(GO:0060346)
0.1	2.2	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.1	5.1	GO:0030101	natural killer cell activation(GO:0030101)
0.1	1.5	GO:0002507	tolerance induction(GO:0002507)
0.1	3.1	GO:0048240	sperm capacitation(GO:0048240)
0.1	0.2	GO:0098759	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1	3.8	GO:0006730	one-carbon metabolic process(GO:0006730)
0.1	2.9	GO:0070932	histone H3 deacetylation(GO:0070932)
0.1	1.9	GO:0019236	response to pheromone(GO:0019236)
0.1	3.6	GO:0006220	pyrimidine nucleotide metabolic process(GO:0006220)
0.1	3.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	0.5	GO:0071926	endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	1.3	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	1.3	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.9	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.1	0.4	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1	3.2	GO:0006972	hyperosmotic response(GO:0006972)
0.1	1.1	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1	0.6	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1	1.2	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.1	0.6	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	1.7	GO:0060037	pharyngeal system development(GO:0060037)
0.1	1.6	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1	10.5	GO:0045727	positive regulation of translation(GO:0045727)
0.1	2.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.3	GO:0014908	myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.1	3.0	GO:0030199	collagen fibril organization(GO:0030199)
0.1	4.6	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.1	0.6	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.1	4.3	GO:0007004	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1	4.1	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.1	0.7	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1	0.8	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1	1.0	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	3.3	GO:1901998	toxin transport(GO:1901998)
0.1	1.9	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.1	2.1	GO:0015701	bicarbonate transport(GO:0015701)
0.1	5.8	GO:0042098	T cell proliferation(GO:0042098)
0.1	0.5	GO:0071680	response to indole-3-methanol(GO:0071680)
0.1	2.6	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.1	0.8	GO:0008298	intracellular mRNA localization(GO:0008298)
0.1	3.5	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1	1.3	GO:0001556	oocyte maturation(GO:0001556)
0.1	3.5	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	3.1	GO:0006284	base-excision repair(GO:0006284)
0.1	0.2	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	7.5	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.1	0.3	GO:0071684	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1	0.8	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	3.3	GO:0033045	regulation of sister chromatid segregation(GO:0033045)
0.1	2.6	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.1	1.0	GO:0001675	acrosome assembly(GO:0001675)
0.1	2.1	GO:0060074	synapse maturation(GO:0060074)
0.1	0.9	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.1	7.7	GO:0043484	regulation of RNA splicing(GO:0043484)
0.1	2.0	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	1.1	GO:0006020	inositol metabolic process(GO:0006020)
0.1	0.6	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.4	GO:0001865	NK T cell differentiation(GO:0001865)
0.1	0.5	GO:0060028	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) convergent extension involved in axis elongation(GO:0060028) convergent extension involved in organogenesis(GO:0060029)
0.1	2.7	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1	2.0	GO:0002181	cytoplasmic translation(GO:0002181)
0.1	5.0	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052)
0.1	1.1	GO:0014002	astrocyte development(GO:0014002)
0.1	3.9	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.1	1.4	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	0.7	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.1	1.6	GO:0090280	positive regulation of calcium ion import(GO:0090280)
0.0	2.0	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.0	1.4	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.3	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	2.8	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	2.0	GO:0030279	negative regulation of ossification(GO:0030279)
0.0	1.2	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0	4.2	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	2.8	GO:0006342	chromatin silencing(GO:0006342)
0.0	3.3	GO:0007127	meiosis I(GO:0007127)
0.0	1.9	GO:0000077	DNA damage checkpoint(GO:0000077)
0.0	1.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	2.8	GO:0048706	embryonic skeletal system development(GO:0048706)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.2	GO:0007398	ectoderm development(GO:0007398)
0.0	0.3	GO:0090169	regulation of spindle assembly(GO:0090169) regulation of mitotic spindle assembly(GO:1901673)
0.0	2.0	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.5	GO:0006308	DNA catabolic process(GO:0006308)
0.0	1.2	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.2	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.9	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.7	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.7	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.0	0.8	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.1	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.0	0.4	GO:1902850	mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0	0.5	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	1.7	GO:0042110	T cell activation(GO:0042110) T cell aggregation(GO:0070489)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.9	24.3	GO:0071953	elastic fiber(GO:0071953)
3.2	9.7	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
1.4	16.6	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
1.4	11.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
1.3	5.2	GO:0036398	TCR signalosome(GO:0036398) microspike(GO:0044393)
1.2	8.6	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
1.1	4.2	GO:0005607	laminin-1 complex(GO:0005606) laminin-2 complex(GO:0005607) laminin-10 complex(GO:0043259)
1.0	9.6	GO:0043020	NADPH oxidase complex(GO:0043020)
0.9	11.5	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.8	19.7	GO:0001891	phagocytic cup(GO:0001891)
0.7	6.5	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.7	2.1	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.7	7.5	GO:0031010	ISWI-type complex(GO:0031010)
0.6	5.1	GO:0097443	sorting endosome(GO:0097443)
0.6	5.0	GO:0000796	condensin complex(GO:0000796)
0.6	6.9	GO:0005833	hemoglobin complex(GO:0005833)
0.6	7.4	GO:0005859	muscle myosin complex(GO:0005859)
0.6	2.9	GO:0043293	apoptosome(GO:0043293)
0.5	20.7	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.5	3.7	GO:0030991	intraciliary transport particle A(GO:0030991)
0.5	1.5	GO:0033557	Slx1-Slx4 complex(GO:0033557)
0.5	3.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.5	2.0	GO:0097427	microtubule bundle(GO:0097427)
0.5	4.8	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.5	2.4	GO:0033553	rDNA heterochromatin(GO:0033553)
0.4	3.1	GO:0036128	CatSper complex(GO:0036128)
0.4	36.5	GO:0031526	brush border membrane(GO:0031526)
0.4	3.6	GO:0032437	cuticular plate(GO:0032437)
0.3	5.8	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3	7.4	GO:0031091	platelet alpha granule(GO:0031091)
0.3	1.2	GO:0044299	C-fiber(GO:0044299)
0.3	3.3	GO:0005915	zonula adherens(GO:0005915)
0.3	4.9	GO:0042613	MHC class II protein complex(GO:0042613)
0.3	2.4	GO:0032584	growth cone membrane(GO:0032584)
0.3	1.1	GO:0071203	WASH complex(GO:0071203)
0.3	4.7	GO:0042589	zymogen granule membrane(GO:0042589)
0.3	7.2	GO:0042629	mast cell granule(GO:0042629)
0.3	2.2	GO:0016282	eukaryotic 43S preinitiation complex(GO:0016282)
0.3	0.8	GO:0044609	DBIRD complex(GO:0044609)
0.3	1.3	GO:1990130	Iml1 complex(GO:1990130)
0.2	0.7	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.2	17.7	GO:0000118	histone deacetylase complex(GO:0000118)
0.2	1.6	GO:0033010	paranodal junction(GO:0033010)
0.2	4.4	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.2	2.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.2	34.1	GO:0001650	fibrillar center(GO:0001650)
0.2	2.8	GO:0032593	insulin-responsive compartment(GO:0032593)
0.2	1.7	GO:0031931	TORC1 complex(GO:0031931)
0.2	0.4	GO:0032807	DNA ligase IV complex(GO:0032807)
0.2	5.9	GO:0005719	nuclear euchromatin(GO:0005719)
0.2	2.5	GO:0000812	Swr1 complex(GO:0000812)
0.2	15.2	GO:0005581	collagen trimer(GO:0005581)
0.2	1.4	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.2	1.4	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.2	17.5	GO:0031985	Golgi cisterna(GO:0031985)
0.2	15.5	GO:0005604	basement membrane(GO:0005604)
0.2	0.9	GO:0035061	interchromatin granule(GO:0035061)
0.2	10.6	GO:0005876	spindle microtubule(GO:0005876)
0.2	2.3	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.2	1.4	GO:0031209	SCAR complex(GO:0031209)
0.2	6.8	GO:0002102	podosome(GO:0002102)
0.2	7.2	GO:0016592	mediator complex(GO:0016592)
0.2	3.4	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2	2.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	1.4	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	3.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	5.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	1.1	GO:0097452	CRD-mediated mRNA stability complex(GO:0070937) GAIT complex(GO:0097452)
0.1	4.6	GO:0005669	transcription factor TFIID complex(GO:0005669) site of double-strand break(GO:0035861)
0.1	11.0	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.1	1.3	GO:0043034	costamere(GO:0043034)
0.1	1.1	GO:0005796	Golgi lumen(GO:0005796)
0.1	3.9	GO:0008180	COP9 signalosome(GO:0008180)
0.1	1.5	GO:0032426	stereocilium tip(GO:0032426)
0.1	7.7	GO:0045178	basal part of cell(GO:0045178)
0.1	0.5	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.1	29.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	3.2	GO:0030131	clathrin adaptor complex(GO:0030131)
0.1	4.8	GO:0015030	Cajal body(GO:0015030)
0.1	1.1	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.1	5.7	GO:0034707	chloride channel complex(GO:0034707)
0.1	7.0	GO:0005811	lipid particle(GO:0005811)
0.1	1.9	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	5.6	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.1	4.4	GO:0016235	aggresome(GO:0016235)
0.1	14.1	GO:0001726	ruffle(GO:0001726)
0.1	2.0	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.5	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	1.4	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1	5.6	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.1	5.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	2.9	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	1.3	GO:0000145	exocyst(GO:0000145)
0.1	2.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	3.2	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	5.2	GO:0030018	Z disc(GO:0030018)
0.1	7.6	GO:0042383	sarcolemma(GO:0042383)
0.1	0.6	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	5.8	GO:0098802	plasma membrane receptor complex(GO:0098802)
0.1	1.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	2.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	1.2	GO:0030686	90S preribosome(GO:0030686)
0.0	4.4	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	2.7	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	9.6	GO:0005840	ribosome(GO:0005840)
0.0	0.7	GO:0001533	cornified envelope(GO:0001533)
0.0	1.7	GO:0005657	replication fork(GO:0005657)
0.0	1.7	GO:0045095	keratin filament(GO:0045095)
0.0	1.6	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.4	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	9.5	GO:0000228	nuclear chromosome(GO:0000228)
0.0	0.9	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.7	GO:0016459	myosin complex(GO:0016459)
0.0	3.4	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.8	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.8	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	6.5	GO:0005813	centrosome(GO:0005813)
0.0	9.4	GO:0005730	nucleolus(GO:0005730)
0.0	2.0	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	2.5	GO:0016607	nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.4	22.2	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
3.8	22.8	GO:0048030	disaccharide binding(GO:0048030)
2.9	11.7	GO:0005143	interleukin-12 receptor binding(GO:0005143)
2.5	9.9	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
2.2	6.7	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
2.0	25.5	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
1.9	7.4	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
1.8	11.0	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.6	4.8	GO:0030977	taurine binding(GO:0030977)
1.5	7.4	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
1.4	13.8	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.4	4.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
1.3	5.3	GO:0097108	hedgehog family protein binding(GO:0097108)
1.3	5.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
1.3	19.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
1.3	3.8	GO:0042895	antibiotic transporter activity(GO:0042895)
1.2	31.0	GO:0042288	MHC class I protein binding(GO:0042288)
1.2	9.7	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.2	4.7	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
1.1	5.5	GO:0004849	uridine kinase activity(GO:0004849)
1.0	22.0	GO:0023026	MHC class II protein complex binding(GO:0023026)
1.0	5.0	GO:0044547	DNA topoisomerase binding(GO:0044547)
1.0	5.0	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.0	2.9	GO:0016882	cyclo-ligase activity(GO:0016882)
1.0	4.8	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.9	5.5	GO:0004568	chitinase activity(GO:0004568)
0.9	3.5	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.8	6.4	GO:0045545	syndecan binding(GO:0045545)
0.8	3.1	GO:0019863	IgE binding(GO:0019863)
0.8	3.9	GO:0042731	PH domain binding(GO:0042731)
0.8	3.8	GO:0000700	mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.7	7.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.7	5.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.7	7.4	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.7	5.3	GO:0038085	vascular endothelial growth factor-activated receptor activity(GO:0005021) vascular endothelial growth factor binding(GO:0038085)
0.7	5.9	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.6	3.9	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.6	1.9	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.6	3.7	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.6	7.9	GO:0042043	neurexin family protein binding(GO:0042043)
0.6	4.8	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.6	3.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.6	7.4	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.6	3.9	GO:0003896	DNA primase activity(GO:0003896)
0.6	3.9	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5	2.6	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.5	2.6	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.5	2.1	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.5	4.6	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.5	3.5	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.5	1.5	GO:0032217	riboflavin transporter activity(GO:0032217)
0.5	2.0	GO:0042610	CD8 receptor binding(GO:0042610)
0.5	6.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.5	3.4	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.5	4.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.5	6.9	GO:0005344	oxygen transporter activity(GO:0005344)
0.4	4.9	GO:0031432	titin binding(GO:0031432)
0.4	4.8	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.4	4.4	GO:0033265	choline binding(GO:0033265)
0.4	2.5	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.4	2.1	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.4	2.4	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4	4.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.4	2.7	GO:0016936	galactoside binding(GO:0016936)
0.4	1.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.4	5.1	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.4	1.1	GO:0000827	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827)
0.4	7.1	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.4	2.8	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.3	5.2	GO:0044548	S100 protein binding(GO:0044548)
0.3	8.0	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3	3.1	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.3	16.8	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.3	7.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3	16.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3	0.6	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.3	2.8	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3	3.0	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.3	3.0	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.3	4.1	GO:0045499	chemorepellent activity(GO:0045499)
0.3	3.8	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.3	2.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.3	1.7	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.3	2.6	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3	11.2	GO:0004601	peroxidase activity(GO:0004601)
0.3	1.4	GO:0031404	chloride ion binding(GO:0031404)
0.3	4.2	GO:0004312	fatty acid synthase activity(GO:0004312)
0.3	21.9	GO:0003725	double-stranded RNA binding(GO:0003725)
0.3	2.2	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.3	2.7	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.3	14.8	GO:0050840	extracellular matrix binding(GO:0050840)
0.3	1.8	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.3	0.8	GO:0016509	long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.3	3.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.3	2.1	GO:0001055	RNA polymerase II activity(GO:0001055)
0.3	1.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.3	1.5	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.2	0.7	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.2	1.0	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2	3.2	GO:0042301	phosphate ion binding(GO:0042301)
0.2	3.4	GO:0015250	water channel activity(GO:0015250)
0.2	0.7	GO:1990763	arrestin family protein binding(GO:1990763)
0.2	20.5	GO:0005178	integrin binding(GO:0005178)
0.2	3.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.2	7.6	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2	2.9	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2	1.5	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.2	3.7	GO:0017160	Ral GTPase binding(GO:0017160)
0.2	8.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.2	16.3	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2	0.8	GO:0032190	acrosin binding(GO:0032190)
0.2	1.2	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.2	1.2	GO:0017040	ceramidase activity(GO:0017040)
0.2	0.8	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.2	0.8	GO:0005333	norepinephrine transmembrane transporter activity(GO:0005333)
0.2	0.6	GO:0003921	GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
0.2	2.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.2	1.5	GO:0034511	U3 snoRNA binding(GO:0034511)
0.2	4.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.2	4.4	GO:0019239	deaminase activity(GO:0019239)
0.2	1.8	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2	4.8	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.2	2.4	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.2	1.9	GO:0008097	5S rRNA binding(GO:0008097)
0.2	0.6	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.2	1.4	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	3.8	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.1	2.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	1.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	3.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	3.7	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	2.7	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	4.7	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	7.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.1	2.5	GO:0042169	SH2 domain binding(GO:0042169)
0.1	6.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	0.5	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.9	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	5.7	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.1	2.7	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.1	1.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.1	4.7	GO:0019843	rRNA binding(GO:0019843)
0.1	0.8	GO:0004445	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1	1.6	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	2.2	GO:0031489	myosin V binding(GO:0031489)
0.1	1.6	GO:0033558	histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1	1.1	GO:0003796	lysozyme activity(GO:0003796)
0.1	0.4	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	12.0	GO:0003714	transcription corepressor activity(GO:0003714)
0.1	0.4	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.2	GO:0004918	interleukin-8 receptor activity(GO:0004918)
0.1	2.0	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	3.7	GO:0017022	myosin binding(GO:0017022)
0.1	2.8	GO:0042605	peptide antigen binding(GO:0042605)
0.1	0.7	GO:0035497	cAMP response element binding(GO:0035497)
0.1	1.9	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	1.9	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	2.1	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.1	8.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	1.8	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	7.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	3.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	5.3	GO:0031490	chromatin DNA binding(GO:0031490)
0.1	2.7	GO:0015485	cholesterol binding(GO:0015485)
0.1	1.9	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.1	6.9	GO:0030165	PDZ domain binding(GO:0030165)
0.1	0.4	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.1	1.9	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.1	2.3	GO:0051119	sugar transmembrane transporter activity(GO:0051119)
0.0	0.2	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	0.6	GO:0019213	deacetylase activity(GO:0019213)
0.0	1.7	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	1.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248)
0.0	6.0	GO:0030695	GTPase regulator activity(GO:0030695)
0.0	0.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	2.1	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	1.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	7.8	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	2.1	GO:0035064	methylated histone binding(GO:0035064)
0.0	2.9	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	2.4	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0	0.6	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.7	GO:0003785	actin monomer binding(GO:0003785)
0.0	4.7	GO:0003712	transcription cofactor activity(GO:0003712)
0.0	0.7	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	9.6	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.5	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	1.3	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	1.9	GO:0004519	endonuclease activity(GO:0004519)
0.0	3.6	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	1.5	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	2.3	GO:0019902	phosphatase binding(GO:0019902)
0.0	4.7	GO:0051020	GTPase binding(GO:0051020)
0.0	10.5	GO:0043565	sequence-specific DNA binding(GO:0043565)
0.0	0.2	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	1.5	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.1	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0	0.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	17.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.5	17.5	PID IL23 PATHWAY	IL23-mediated signaling events
0.5	9.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5	5.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.5	7.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.5	17.9	PID RAS PATHWAY	Regulation of Ras family activation
0.5	15.9	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.4	6.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.4	14.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.4	8.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.3	4.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.3	16.4	NABA COLLAGENS	Genes encoding collagen proteins
0.3	11.0	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.3	9.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.3	15.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.3	4.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.3	5.6	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.2	3.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	32.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2	5.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.2	6.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	0.7	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.2	2.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.2	1.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.2	5.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.2	3.6	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	3.2	PID EPO PATHWAY	EPO signaling pathway
0.1	4.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	5.8	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	3.4	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	0.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	4.7	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	6.1	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	5.0	PID AURORA B PATHWAY	Aurora B signaling
0.1	3.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	4.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	1.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	1.8	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.1	2.1	PID RHOA PATHWAY	RhoA signaling pathway
0.1	2.2	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	2.8	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.1	1.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	2.0	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	0.5	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	2.4	PID PLK1 PATHWAY	PLK1 signaling events
0.1	0.6	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	9.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	2.0	PID ATM PATHWAY	ATM pathway
0.1	3.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	1.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	2.0	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.7	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.8	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	1.3	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.2	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	19.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.4	11.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
1.2	14.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
1.0	9.7	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.6	5.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.6	5.8	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.6	28.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.5	5.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.5	6.8	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.4	5.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.4	6.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4	2.8	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.4	28.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.3	2.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.3	6.3	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.3	19.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	4.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.3	12.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.3	28.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3	4.4	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.3	10.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3	5.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.3	3.8	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3	3.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.3	3.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.3	6.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3	6.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.2	6.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	1.4	REACTOME DEFENSINS	Genes involved in Defensins
0.2	4.6	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.2	2.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.2	2.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.2	4.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.2	3.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.2	11.5	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.2	5.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.2	5.7	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2	7.0	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.2	4.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	2.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2	6.5	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.2	0.5	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.2	2.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	2.5	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	3.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	3.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.1	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	2.1	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	2.2	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	5.6	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	4.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	2.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	0.4	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	2.3	REACTOME KINESINS	Genes involved in Kinesins
0.1	1.8	REACTOME INTERFERON SIGNALING	Genes involved in Interferon Signaling
0.1	6.7	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	2.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.7	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	1.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	0.4	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.1	1.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	0.8	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	1.3	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1	1.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	1.9	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	1.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.7	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	1.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.8	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.8	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.2	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation

Results for Ubp1

Z-value: 0.88

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Transcription factors associated with Ubp1

Activity-expression correlation:

Activity profile of Ubp1 motif

Sorted Z-values of Ubp1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ubp1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: