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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zbtb18

Z-value: 1.47

Motif logo

Transcription factors associated with Zbtb18

Gene Symbol Gene ID Gene Info

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp238rn6_v1_chr13_+_95589668_95589668-0.526.2e-24Click!

Activity profile of Zbtb18 motif

Sorted Z-values of Zbtb18 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_128046780 130.12 ENSRNOT00000078064
Ab1-233
chr16_+_6970342 92.96 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr2_+_252452269 79.62 ENSRNOT00000021970
urate oxidase
chr16_+_18690246 71.25 ENSRNOT00000081484
methionine adenosyltransferase 1A
chr13_+_78805347 68.61 ENSRNOT00000003748
serpin family C member 1
chr1_-_170431073 66.43 ENSRNOT00000024710
hemopexin
chr3_+_28416954 65.45 ENSRNOT00000043533
kynureninase
chr16_+_18690649 63.27 ENSRNOT00000015190
methionine adenosyltransferase 1A
chr4_+_65110746 60.11 ENSRNOT00000017675
aldo-keto reductase family 1, member D1
chr1_+_83714347 55.88 ENSRNOT00000085245
cytochrome P450, family 2, subfamily a, polypeptide 1
chr5_-_134484839 54.14 ENSRNOT00000045571
ENSRNOT00000012681
cytochrome P450, family 4, subfamily a, polypeptide 2
chr1_+_83163079 53.83 ENSRNOT00000077725
ENSRNOT00000034845
cytochrome P450, family 2, subfamily b, polypeptide 3
chrX_+_143097525 51.48 ENSRNOT00000004559
coagulation factor IX
chr17_+_8489266 50.59 ENSRNOT00000016252
leukocyte cell-derived chemotaxin 2
chr2_+_114413410 49.76 ENSRNOT00000015866
solute carrier family 2 member 2
chr4_+_122244711 46.97 ENSRNOT00000038251
urocanate hydratase 1
chr16_-_7007287 44.57 ENSRNOT00000041216
inter-alpha trypsin inhibitor, heavy chain 3
chr20_+_28989491 44.50 ENSRNOT00000074524
phospholipase A2, group XIIB
chr16_-_7007051 44.43 ENSRNOT00000023984
inter-alpha trypsin inhibitor, heavy chain 3
chr1_+_48273611 44.17 ENSRNOT00000022254
ENSRNOT00000022068
solute carrier family 22 member 1
chr19_-_43911057 43.86 ENSRNOT00000026017
chymotrypsinogen B1
chr6_-_127816055 42.37 ENSRNOT00000013175
serine (or cysteine) proteinase inhibitor, clade A, member 3M
chr5_-_19368431 41.89 ENSRNOT00000012819
cytochrome P450, family 7, subfamily a, polypeptide 1
chr10_+_90085559 41.31 ENSRNOT00000028332
N-acetylglutamate synthase
chr5_+_61425746 41.13 ENSRNOT00000064113
hypothetical LOC298077
chr8_-_85645718 41.02 ENSRNOT00000032185
glutathione S-transferase alpha 2
chr14_+_22724399 39.25 ENSRNOT00000002724
UDP glucuronosyltransferase 2 family, polypeptide B10
chr14_+_77067503 37.98 ENSRNOT00000085275
solute carrier family 2 member 9
chr2_+_243550627 37.45 ENSRNOT00000085067
ENSRNOT00000083682
alcohol dehydrogenase 1 (class I)
chr7_+_93975451 37.41 ENSRNOT00000011379
collectin subfamily member 10
chr11_-_66034573 35.91 ENSRNOT00000003645
homogentisate 1, 2-dioxygenase
chr14_+_22142364 35.53 ENSRNOT00000002699
sulfotransferase family 1B member 1
chr3_+_159902441 34.66 ENSRNOT00000089893
ENSRNOT00000011978
hepatocyte nuclear factor 4, alpha
chr1_+_189364288 34.36 ENSRNOT00000080338
acyl-CoA synthetase medium-chain family member 1
chr4_+_65112944 31.94 ENSRNOT00000083672
aldo-keto reductase family 1, member D1
chr8_-_50539331 31.02 ENSRNOT00000088997

chr1_+_263554453 31.00 ENSRNOT00000070861
ATP binding cassette subfamily C member 2
chr10_-_62254287 30.92 ENSRNOT00000004313
serpin family F member 1
chr1_-_163328591 29.78 ENSRNOT00000034843
tsukushi, small leucine rich proteoglycan
chr20_-_5806097 29.57 ENSRNOT00000000611
colipase
chr13_+_83073544 28.77 ENSRNOT00000066119
ENSRNOT00000079796
ENSRNOT00000077070
dermatopontin
chr13_+_83073866 28.61 ENSRNOT00000075996
dermatopontin
chr13_-_56958549 28.58 ENSRNOT00000017293
ENSRNOT00000083912
similar to complement factor H-related protein
chr4_-_176679815 28.11 ENSRNOT00000090122
glycogen synthase 2
chr17_-_35958077 27.78 ENSRNOT00000038532
angiotensin II receptor, type 1a
chr20_-_12820466 27.60 ENSRNOT00000001699
formimidoyltransferase cyclodeaminase
chr13_-_89433815 27.54 ENSRNOT00000091541
Fc fragment of IgG receptor IIb
chr20_-_5805627 27.16 ENSRNOT00000085996
colipase
chr1_+_279896973 27.09 ENSRNOT00000068119
pancreatic lipase related protein 2
chr17_+_43458553 27.06 ENSRNOT00000088939
solute carrier family 17, member 4
chr9_+_4269160 26.80 ENSRNOT00000050420
sulfotransferase family 1C member 2
chr19_-_57333433 25.63 ENSRNOT00000024917
angiotensinogen
chr7_+_95074236 24.02 ENSRNOT00000067649
collagen type XIV alpha 1 chain
chr6_-_7961207 23.96 ENSRNOT00000007174
ATP binding cassette subfamily G member 5
chr1_-_260638816 23.51 ENSRNOT00000065632
ENSRNOT00000017938
ENSRNOT00000077962
phosphoinositide-3-kinase adaptor protein 1
chr19_-_37907714 23.25 ENSRNOT00000026361
chymotrypsin-like
chr5_+_60528997 22.57 ENSRNOT00000051445
glyoxylate and hydroxypyruvate reductase
chr1_+_167937026 22.45 ENSRNOT00000020655
olfactory receptor 57
chrX_+_15669191 22.21 ENSRNOT00000013553
MAGI family member, X-linked
chr14_+_22417206 21.52 ENSRNOT00000052369
UDP-glucuronosyltransferase 2 family, member 37
chr20_-_27117663 21.30 ENSRNOT00000000434
phenazine biosynthesis-like protein domain containing 1
chr1_-_252849756 21.25 ENSRNOT00000025845
ENSRNOT00000078279
lipase A, lysosomal acid type
chr19_-_43848937 21.05 ENSRNOT00000044844
lactate dehydrogenase D
chr2_-_195423787 19.98 ENSRNOT00000071603
selenium-binding protein 1
chr4_-_23135354 19.90 ENSRNOT00000011432
STEAP4 metalloreductase
chr13_-_98478327 19.47 ENSRNOT00000030135
coenzyme Q8A
chr8_+_112594691 19.39 ENSRNOT00000038383
ENSRNOT00000081281
acyl-CoA dehydrogenase family, member 11
chr1_+_201981357 19.37 ENSRNOT00000027999
acyl-CoA dehydrogenase, short/branched chain
chr6_-_26828972 19.33 ENSRNOT00000010932
elastin microfibril interfacer 1
chr3_-_46361092 18.96 ENSRNOT00000008987
CD302 molecule
chr4_-_22192474 18.91 ENSRNOT00000043822
ATP binding cassette subfamily B member 1A
chr2_-_196113149 17.93 ENSRNOT00000088465
selenium binding protein 1
chr1_+_252589785 17.80 ENSRNOT00000025928
Fas cell surface death receptor
chr10_+_83655460 17.58 ENSRNOT00000008011
G protein subunit gamma transducin 2
chr1_-_275882444 17.28 ENSRNOT00000083215
glycerol-3-phosphate acyltransferase, mitochondrial
chr1_+_21613148 17.10 ENSRNOT00000018695
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr7_-_15225309 16.82 ENSRNOT00000075589
ENSRNOT00000066095
cytochrome P450, family 4, subfamily f, polypeptide 6
chr10_+_104377748 16.73 ENSRNOT00000080714
LLGL2, scribble cell polarity complex component
chr5_+_159845774 16.58 ENSRNOT00000012328
Eph receptor A2
chr3_-_2853272 16.46 ENSRNOT00000023022
ficolin A
chr14_+_2050483 15.87 ENSRNOT00000000047
solute carrier family 26 member 1
chr2_+_200793571 15.69 ENSRNOT00000091444
hydroxyacid oxidase 2
chr10_+_58776792 15.65 ENSRNOT00000019574
thioredoxin domain containing 17
chr1_+_247238798 15.65 ENSRNOT00000083511
RNA terminal phosphate cyclase-like 1
chr10_-_98388637 15.61 ENSRNOT00000005665
ATP-binding cassette, subfamily A (ABC1), member 8a
chr7_+_26522314 15.35 ENSRNOT00000011572
solute carrier family 41 member 2
chr9_+_52023295 15.10 ENSRNOT00000004956
collagen type III alpha 1 chain
chr17_+_81352700 15.10 ENSRNOT00000024736
mannose receptor, C type 1
chr5_+_152290084 15.08 ENSRNOT00000089849
absent in melanoma 1-like
chr8_+_22750336 15.02 ENSRNOT00000013496
low density lipoprotein receptor
chr13_+_91481461 14.96 ENSRNOT00000012103
olfactory receptor 1576
chr1_+_217173199 14.91 ENSRNOT00000075078
SH3 and multiple ankyrin repeat domains 2
chr17_+_18059382 14.64 ENSRNOT00000031656
NHL repeat containing E3 ubiquitin protein ligase 1
chr6_+_107517668 14.42 ENSRNOT00000013753
acyl-CoA thioesterase 4
chr4_-_119188251 14.39 ENSRNOT00000057350
gastrokine 3
chr13_-_53870428 14.27 ENSRNOT00000000812
nuclear receptor subfamily 5, group A, member 2
chr18_+_70739492 14.23 ENSRNOT00000085601
acetyl-CoA acyltransferase 2
chr8_+_119261747 14.22 ENSRNOT00000079648

chr8_+_71168097 14.12 ENSRNOT00000081375
RNA binding protein with multiple splicing 2
chr6_+_7961413 14.08 ENSRNOT00000007638
ENSRNOT00000061871
ATP binding cassette subfamily G member 8
chr1_-_164671577 14.01 ENSRNOT00000091807
solute carrier organic anion transporter family, member 2b1
chr14_+_59611434 14.00 ENSRNOT00000065366
cholecystokinin A receptor
chr15_-_49505553 13.96 ENSRNOT00000028974
ADAM-like, decysin 1
chrX_-_6620722 13.96 ENSRNOT00000066674
monoamine oxidase A
chr4_+_156752082 13.59 ENSRNOT00000084588
ENSRNOT00000068407
CD163 molecule
chr9_-_71900044 13.37 ENSRNOT00000020322
isocitrate dehydrogenase (NADP(+)) 1, cytosolic
chr1_-_164659992 13.32 ENSRNOT00000024281
solute carrier organic anion transporter family, member 2b1
chrX_+_110818716 13.24 ENSRNOT00000086308
ring finger protein 128, E3 ubiquitin protein ligase
chr10_-_104564480 13.03 ENSRNOT00000008525
galactokinase 1
chr10_-_98018014 12.79 ENSRNOT00000005367
FAM20A, golgi associated secretory pathway pseudokinase
chr11_-_77593171 12.69 ENSRNOT00000002645
ENSRNOT00000043498
interleukin 1 receptor accessory protein
chr11_+_44192940 12.65 ENSRNOT00000002255
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr13_-_108460362 12.63 ENSRNOT00000048200
Da2-20
chr4_+_157126935 12.43 ENSRNOT00000056051
complement C1r
chr10_+_84718824 12.38 ENSRNOT00000055464
coatomer protein complex, subunit zeta 2
chr11_-_90406797 12.33 ENSRNOT00000073049
snail family transcriptional repressor 2
chr19_-_43841795 12.24 ENSRNOT00000079539
lactate dehydrogenase D
chr11_-_62451149 11.99 ENSRNOT00000093686
ENSRNOT00000081443
zinc finger and BTB domain containing 20
chr16_+_54332660 11.67 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr8_-_78233430 11.60 ENSRNOT00000083220
cingulin-like 1
chr1_-_146289465 11.56 ENSRNOT00000017362
abhydrolase domain containing 17C
chr3_+_2288667 11.54 ENSRNOT00000012289
ectonucleoside triphosphate diphosphohydrolase 8
chr1_-_169856727 11.50 ENSRNOT00000047978
olfactory receptor 180
chr1_+_184301493 11.40 ENSRNOT00000078096
inscuteable homolog (Drosophila)
chr13_+_41883137 11.39 ENSRNOT00000004581
solute carrier family 35, member F5
chr1_+_72810545 11.32 ENSRNOT00000092117
protein tyrosine phosphatase, receptor type, H
chr9_+_100156154 11.29 ENSRNOT00000005935
aquaporin 12A
chr15_+_4554603 11.25 ENSRNOT00000075153
potassium two pore domain channel subfamily K member 5
chr10_+_4719713 11.24 ENSRNOT00000003412
lipopolysaccharide-induced TNF factor
chr5_+_137356801 10.98 ENSRNOT00000027432
similar to RIKEN cDNA 2610528J11
chr13_+_99221013 10.90 ENSRNOT00000083608
transmembrane protein 63a
chr1_-_153740905 10.68 ENSRNOT00000023239
protease, serine, 23
chr15_+_29073755 10.55 ENSRNOT00000075409

chr18_-_25314047 10.32 ENSRNOT00000079778

chr1_+_203160323 10.31 ENSRNOT00000027919

chr3_+_2642531 10.00 ENSRNOT00000081798
fucosyltransferase 7
chr13_-_80702315 9.95 ENSRNOT00000004577
flavin containing monooxygenase 4
chr1_-_215451156 9.59 ENSRNOT00000066317

chr3_+_72460889 9.59 ENSRNOT00000012209
tankyrase 1 binding protein 1
chr8_+_71167305 9.45 ENSRNOT00000021337
RNA binding protein with multiple splicing 2
chrX_-_111942749 9.33 ENSRNOT00000087583

chr17_+_72209373 9.18 ENSRNOT00000064802
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr10_+_14105750 9.12 ENSRNOT00000090552
methionine sulfoxide reductase B1
chr11_+_61661724 9.06 ENSRNOT00000079423
zinc finger, DHHC-type containing 23
chr20_+_6877091 8.99 ENSRNOT00000093654
similar to GI:13385412-like protein splice form I
chr4_-_64981384 8.95 ENSRNOT00000017338
cAMP responsive element binding protein 3-like 2
chr8_+_70994563 8.82 ENSRNOT00000051504
ENSRNOT00000077163
spastic paraplegia 21 homolog (human)
chr3_+_119805941 8.78 ENSRNOT00000018584
adrenoceptor alpha 2B
chr11_+_66713888 8.71 ENSRNOT00000003340
F-box protein 40
chr8_-_21995806 8.64 ENSRNOT00000028034
sphingosine-1-phosphate receptor 2
chr1_-_137359072 8.62 ENSRNOT00000014553
kelch-like family member 25
chr11_+_70967439 8.58 ENSRNOT00000032518
IQ motif containing G
chrX_-_26376467 8.55 ENSRNOT00000051655
ENSRNOT00000036502
Rho GTPase activating protein 6
chr1_+_100199057 8.45 ENSRNOT00000025831
kallikrein 1
chr11_+_61662270 8.42 ENSRNOT00000079521
zinc finger, DHHC-type containing 23
chr10_+_14656812 8.41 ENSRNOT00000024904
protease, serine, 34
chr18_+_12008759 8.29 ENSRNOT00000022665
ENSRNOT00000061344
ENSRNOT00000038635
desmoglein 1
chr3_+_138024508 8.28 ENSRNOT00000007794
destrin, actin depolymerizing factor
chr5_-_155264143 8.24 ENSRNOT00000017385
complement C1q A chain
chr20_+_14101659 8.17 ENSRNOT00000072696
guanylyl cyclase domain containing 1
chr4_-_117631716 8.01 ENSRNOT00000057475
RNA/RNP complex-1-interacting phosphatase
chr10_-_40805941 7.92 ENSRNOT00000017588
antioxidant 1 copper chaperone
chr13_-_50514151 7.90 ENSRNOT00000003951
renin
chr19_-_23554594 7.88 ENSRNOT00000004590
interleukin 15
chr16_-_68936869 7.86 ENSRNOT00000058643
testis expressed gene 24
chr8_+_90304148 7.81 ENSRNOT00000001195

chr1_+_217018916 7.77 ENSRNOT00000028195
ENSRNOT00000078979
7-dehydrocholesterol reductase
chr4_-_78458179 7.72 ENSRNOT00000078473
ENSRNOT00000011327
transmembrane protein 176B
chr5_-_139864393 7.71 ENSRNOT00000030016
zinc finger protein 69
chr19_-_9765484 7.65 ENSRNOT00000016626
SET domain containing 6
chr1_-_141188031 7.64 ENSRNOT00000044567
DNA polymerase gamma, catalytic subunit
chr20_+_3178250 7.59 ENSRNOT00000082116
RT1 class Ib, locus S3
chr7_+_136037230 7.43 ENSRNOT00000071423

chr10_+_69737328 7.38 ENSRNOT00000055999
ENSRNOT00000076773
transmembrane protein 132E
chr7_+_120202601 7.37 ENSRNOT00000082862

chr13_+_42008842 7.21 ENSRNOT00000038811
G protein-coupled receptor 39
chr1_-_168283863 7.17 ENSRNOT00000021115
olfactory receptor 80
chr5_-_58917822 7.16 ENSRNOT00000082554

chr3_+_11679530 7.16 ENSRNOT00000074562
ENSRNOT00000071801
endoglin
chr18_-_64061472 7.15 ENSRNOT00000022519
family with sequence similarity 210, member A
chr8_+_14060394 7.15 ENSRNOT00000014827
single-pass membrane protein with coiled-coil domains 4
chr3_-_48604097 7.12 ENSRNOT00000009620
interferon induced with helicase C domain 1
chr12_+_41155497 7.09 ENSRNOT00000041741
2'-5' oligoadenylate synthetase 1G
chr2_-_248484100 7.07 ENSRNOT00000040856
guanylate binding protein 3
chr17_+_77176716 7.07 ENSRNOT00000083342
ENSRNOT00000024162
optineurin
chr5_+_158042587 7.04 ENSRNOT00000090593
taste 1 receptor member 2
chr10_+_87774552 7.03 ENSRNOT00000044342
keratin associated protein 9-1
chr1_+_167956337 6.98 ENSRNOT00000090675

chr1_-_252116971 6.95 ENSRNOT00000035013
lipase, member O1
chr4_+_7257752 6.91 ENSRNOT00000088357
transmembrane and ubiquitin-like domain containing 1
chr2_+_112914375 6.89 ENSRNOT00000092737
neutral cholesterol ester hydrolase 1
chr5_+_154552195 6.88 ENSRNOT00000072864
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr1_-_101054851 6.85 ENSRNOT00000027849
proline rich and Gla domain 2
chr10_-_35716260 6.83 ENSRNOT00000004308
ENSRNOT00000059255
sequestosome 1
chr4_-_29092753 6.80 ENSRNOT00000014810
Bet1 golgi vesicular membrane trafficking protein
chr1_+_172264473 6.75 ENSRNOT00000050651
olfactory receptor 246
chr7_+_118692851 6.71 ENSRNOT00000091911
apolipoprotein L3-like
chr13_-_104080631 6.66 ENSRNOT00000032865
lysophospholipase-like 1
chr5_-_56536772 6.65 ENSRNOT00000060765
DEXD/H-box helicase 58
chr6_+_48866601 6.64 ENSRNOT00000077321
ENSRNOT00000079891
peroxidasin

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
26.9 134.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
17.2 68.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
16.6 66.4 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
16.4 65.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
14.9 74.6 GO:0006548 histidine catabolic process(GO:0006548)
14.4 57.6 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
13.7 41.1 GO:0046865 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
13.5 54.1 GO:0048252 lauric acid metabolic process(GO:0048252)
12.5 37.5 GO:0006117 acetaldehyde metabolic process(GO:0006117)
10.0 49.8 GO:0009758 carbohydrate utilization(GO:0009758) fructose transport(GO:0015755)
9.8 137.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
8.7 34.7 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
8.3 41.3 GO:0006526 arginine biosynthetic process(GO:0006526)
8.1 81.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
8.0 55.9 GO:0009804 coumarin metabolic process(GO:0009804)
7.8 31.0 GO:0050787 detoxification of mercury ion(GO:0050787)
7.5 15.0 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899)
7.1 21.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
6.9 27.5 GO:0002434 immune complex clearance(GO:0002434)
6.8 27.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
6.3 38.0 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
6.0 29.8 GO:0061073 ciliary body morphogenesis(GO:0061073)
5.9 35.5 GO:0009812 flavonoid metabolic process(GO:0009812)
5.8 189.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
5.7 17.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
5.2 15.7 GO:0018924 mandelate metabolic process(GO:0018924)
5.1 46.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
4.9 19.5 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
4.8 14.4 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
4.7 18.9 GO:0043215 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) response to cyclosporin A(GO:1905237) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
4.6 18.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
4.5 35.9 GO:1902222 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
4.4 53.4 GO:0042738 exogenous drug catabolic process(GO:0042738)
4.4 44.2 GO:0015697 quaternary ammonium group transport(GO:0015697)
4.4 13.1 GO:0035483 gastric emptying(GO:0035483)
4.3 13.0 GO:0006059 hexitol metabolic process(GO:0006059)
4.2 12.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
4.2 16.7 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
4.1 16.6 GO:1901491 notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319) negative regulation of lymphangiogenesis(GO:1901491)
4.1 16.5 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
3.9 27.1 GO:0019374 galactolipid metabolic process(GO:0019374)
3.7 41.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
3.6 25.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
3.6 14.3 GO:0061113 pancreas morphogenesis(GO:0061113)
3.6 14.2 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
3.5 14.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
3.3 13.4 GO:0060696 regulation of phospholipid catabolic process(GO:0060696)
3.0 9.1 GO:0030091 protein repair(GO:0030091)
2.9 5.7 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
2.8 5.7 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
2.7 8.0 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
2.6 7.9 GO:0015680 intracellular copper ion transport(GO:0015680)
2.6 7.9 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
2.6 15.6 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
2.6 7.8 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
2.6 12.8 GO:0044691 tooth eruption(GO:0044691)
2.5 7.6 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
2.4 38.0 GO:0046415 urate metabolic process(GO:0046415)
2.2 8.8 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
2.2 4.3 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
2.1 8.3 GO:0030043 actin filament fragmentation(GO:0030043)
2.0 4.1 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
2.0 14.0 GO:0042420 dopamine catabolic process(GO:0042420)
2.0 19.9 GO:0015677 copper ion import(GO:0015677)
2.0 9.9 GO:0042737 drug catabolic process(GO:0042737)
1.9 9.7 GO:0045297 mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
1.9 7.7 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.9 17.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
1.8 5.5 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
1.8 9.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
1.8 5.4 GO:1902953 endoplasmic reticulum membrane organization(GO:0090158) positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
1.8 80.0 GO:0030199 collagen fibril organization(GO:0030199)
1.8 19.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.7 6.7 GO:0002084 protein depalmitoylation(GO:0002084)
1.7 6.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
1.6 4.9 GO:0006567 threonine catabolic process(GO:0006567)
1.6 6.3 GO:1990375 baculum development(GO:1990375)
1.6 6.3 GO:0009597 detection of virus(GO:0009597)
1.6 4.7 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
1.5 100.6 GO:0032094 response to food(GO:0032094)
1.5 3.0 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
1.4 8.6 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.4 7.0 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
1.4 42.1 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
1.4 4.2 GO:0019401 fumarate metabolic process(GO:0006106) glycerol biosynthetic process(GO:0006114) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)
1.3 17.5 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.3 3.9 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
1.3 11.5 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
1.3 20.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.3 3.8 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
1.2 3.7 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) positive regulation of interleukin-10 biosynthetic process(GO:0045082)
1.2 2.4 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
1.2 15.6 GO:0099562 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
1.2 7.1 GO:0039530 MDA-5 signaling pathway(GO:0039530)
1.1 3.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
1.1 8.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.0 3.1 GO:1900756 protein processing in phagocytic vesicle(GO:1900756) regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
1.0 19.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
1.0 3.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
1.0 9.0 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
1.0 15.9 GO:1902358 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.9 4.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.9 3.7 GO:0060701 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.9 2.7 GO:0009644 response to high light intensity(GO:0009644)
0.9 7.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.9 2.6 GO:0033123 positive regulation of purine nucleotide catabolic process(GO:0033123)
0.9 4.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.8 4.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.8 4.8 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.8 4.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.8 1.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.8 7.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.8 0.8 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.7 3.7 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.7 3.6 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.7 10.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.7 12.6 GO:0097503 sialylation(GO:0097503)
0.7 4.1 GO:0002001 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.7 6.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.7 6.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.7 16.8 GO:0006691 leukotriene metabolic process(GO:0006691)
0.7 4.6 GO:0010587 miRNA catabolic process(GO:0010587) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.7 2.0 GO:1990790 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
0.6 2.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.6 13.2 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.6 3.1 GO:0015793 glycerol transport(GO:0015793)
0.6 49.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.6 3.1 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.6 2.5 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.6 3.0 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.6 9.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.6 5.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.6 4.6 GO:0060482 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.6 2.3 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.6 11.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.5 2.2 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.5 1.6 GO:0010446 response to alkaline pH(GO:0010446)
0.5 12.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.5 4.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.5 8.5 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.5 1.4 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.5 4.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.5 4.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 21.7 GO:0006956 complement activation(GO:0006956)
0.4 11.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.4 17.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.4 15.1 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.4 8.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.4 4.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.4 1.5 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.4 13.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.4 6.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.4 1.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.4 2.8 GO:0016584 nucleosome positioning(GO:0016584)
0.3 3.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.3 1.7 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 3.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.3 1.6 GO:0035983 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.3 1.0 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.3 1.3 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3 3.2 GO:0060290 transdifferentiation(GO:0060290)
0.3 3.6 GO:0097264 self proteolysis(GO:0097264)
0.3 4.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.3 413.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3 38.1 GO:0031638 zymogen activation(GO:0031638)
0.3 5.3 GO:0001945 lymph vessel development(GO:0001945)
0.3 1.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 1.5 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.3 3.6 GO:0022904 respiratory electron transport chain(GO:0022904)
0.3 11.4 GO:0060479 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.3 1.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 5.6 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.3 2.0 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.3 5.0 GO:0006020 inositol metabolic process(GO:0006020)
0.3 5.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3 3.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 2.4 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.3 4.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.3 3.4 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.3 4.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.3 1.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 2.9 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.2 3.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 1.0 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.2 5.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.2 0.7 GO:0032197 transposition, RNA-mediated(GO:0032197)
0.2 1.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 3.3 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.2 0.9 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.2 12.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.2 5.4 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.2 15.7 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.2 26.1 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.2 2.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.2 3.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 1.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 9.2 GO:0006119 oxidative phosphorylation(GO:0006119)
0.2 38.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.2 14.4 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.2 2.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 2.5 GO:0019236 response to pheromone(GO:0019236)
0.2 1.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 0.6 GO:0031053 primary miRNA processing(GO:0031053)
0.1 3.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 5.1 GO:0016925 protein sumoylation(GO:0016925)
0.1 5.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 5.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 6.2 GO:0032570 response to progesterone(GO:0032570)
0.1 8.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 1.6 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.2 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 2.5 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.1 2.3 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 7.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 8.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 3.9 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 9.4 GO:0042742 defense response to bacterium(GO:0042742)
0.1 0.3 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.1 5.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 1.0 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 2.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.3 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 2.0 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 1.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0035745 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 3.6 GO:0009408 response to heat(GO:0009408)
0.0 2.9 GO:0051282 sequestering of calcium ion(GO:0051208) release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 2.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.5 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.8 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.7 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.8 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 1.2 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
12.7 38.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
5.5 27.6 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
4.0 79.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
3.9 30.9 GO:0043203 axon hillock(GO:0043203)
3.8 49.9 GO:0046581 intercellular canaliculus(GO:0046581)
3.6 17.8 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
2.9 389.5 GO:0072562 blood microparticle(GO:0072562)
2.5 7.6 GO:0005760 gamma DNA polymerase complex(GO:0005760)
2.5 7.6 GO:0032398 MHC class Ib protein complex(GO:0032398)
2.3 32.0 GO:0031983 vesicle lumen(GO:0031983)
2.2 58.0 GO:0005640 nuclear outer membrane(GO:0005640)
2.1 15.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
2.0 3.9 GO:0097342 ripoptosome(GO:0097342)
1.5 27.1 GO:0042589 zymogen granule membrane(GO:0042589)
1.4 7.0 GO:1903767 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
1.3 15.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.1 9.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
1.0 20.0 GO:0005614 interstitial matrix(GO:0005614)
1.0 114.5 GO:0016363 nuclear matrix(GO:0016363)
0.8 50.0 GO:0005581 collagen trimer(GO:0005581)
0.8 33.0 GO:0005902 microvillus(GO:0005902)
0.8 8.6 GO:0002177 manchette(GO:0002177)
0.8 12.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.8 3.1 GO:0097513 myosin II filament(GO:0097513)
0.7 36.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.6 2.6 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.6 6.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.6 6.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.6 6.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.6 38.0 GO:0055037 recycling endosome(GO:0055037)
0.6 3.9 GO:0070449 elongin complex(GO:0070449)
0.5 9.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.5 1.8 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4 17.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 3.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 4.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 6.1 GO:0044754 autolysosome(GO:0044754)
0.4 17.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.4 1.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 15.6 GO:0060170 ciliary membrane(GO:0060170)
0.4 8.3 GO:0030057 desmosome(GO:0030057)
0.4 2.9 GO:0043202 lysosomal lumen(GO:0043202)
0.4 2.8 GO:0016589 NURF complex(GO:0016589)
0.3 4.8 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 5.1 GO:0035102 PRC1 complex(GO:0035102)
0.3 2.3 GO:0005683 U7 snRNP(GO:0005683)
0.3 1.0 GO:0000814 ESCRT II complex(GO:0000814)
0.3 8.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 47.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 5.5 GO:0043196 varicosity(GO:0043196)
0.3 1.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.3 211.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.3 3.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.3 1.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 5.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 1.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.3 17.6 GO:0045095 keratin filament(GO:0045095)
0.2 3.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 1.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 107.7 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 0.9 GO:0000938 GARP complex(GO:0000938)
0.2 3.6 GO:0036038 MKS complex(GO:0036038)
0.2 257.1 GO:0005615 extracellular space(GO:0005615)
0.2 3.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 40.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 2.5 GO:0001533 cornified envelope(GO:0001533)
0.2 2.2 GO:0060077 inhibitory synapse(GO:0060077)
0.2 4.3 GO:0001772 immunological synapse(GO:0001772)
0.2 1.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 9.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.7 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 4.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 2.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 10.1 GO:0030027 lamellipodium(GO:0030027)
0.1 4.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.8 GO:0005916 fascia adherens(GO:0005916)
0.1 9.6 GO:0016324 apical plasma membrane(GO:0016324)
0.1 5.0 GO:0031594 neuromuscular junction(GO:0031594)
0.1 37.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 7.2 GO:0010008 endosome membrane(GO:0010008)
0.1 11.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 4.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 4.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 5.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.7 GO:0043195 terminal bouton(GO:0043195)
0.1 95.1 GO:0005739 mitochondrion(GO:0005739)
0.1 0.5 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 2.2 GO:0000502 proteasome complex(GO:0000502)
0.1 1.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 3.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.9 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 2.3 GO:0005811 lipid particle(GO:0005811)
0.1 87.0 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.6 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 12.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 142.0 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 1.8 GO:0031252 cell leading edge(GO:0031252)
0.0 0.3 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
44.8 134.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
30.7 92.0 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
21.8 65.4 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
18.0 54.1 GO:0008405 arachidonic acid 11,12-epoxygenase activity(GO:0008405)
14.7 44.2 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
11.7 81.8 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
10.3 41.3 GO:0034618 arginine binding(GO:0034618)
9.3 27.8 GO:0031711 bradykinin receptor binding(GO:0031711)
7.4 66.4 GO:0015232 heme transporter activity(GO:0015232)
6.5 19.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
6.4 19.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
6.2 37.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
5.7 17.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
5.5 49.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
5.5 27.6 GO:0016841 ammonia-lyase activity(GO:0016841)
5.3 21.2 GO:0004771 sterol esterase activity(GO:0004771)
5.2 15.7 GO:0052853 very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
5.1 35.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
4.7 37.9 GO:0008430 selenium binding(GO:0008430)
4.5 13.4 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
4.3 13.0 GO:0004335 galactokinase activity(GO:0004335)
4.3 34.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
4.2 12.7 GO:0002114 interleukin-33 receptor activity(GO:0002114)
4.1 109.7 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
4.0 28.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
3.8 38.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
3.8 18.9 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
3.6 17.8 GO:0043120 tumor necrosis factor binding(GO:0043120)
3.4 27.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
3.3 93.0 GO:0005540 hyaluronic acid binding(GO:0005540)
3.3 19.9 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
3.0 15.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
2.9 35.2 GO:0019864 IgG binding(GO:0019864)
2.9 8.8 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
2.9 34.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
2.9 17.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
2.8 55.5 GO:0005537 mannose binding(GO:0005537)
2.7 8.0 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
2.6 25.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
2.4 2.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
2.4 7.2 GO:0005534 galactose binding(GO:0005534)
2.3 9.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.3 41.0 GO:0043295 glutathione binding(GO:0043295)
2.2 6.5 GO:0038100 nodal binding(GO:0038100)
2.1 64.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
2.1 6.2 GO:0031765 galanin receptor binding(GO:0031763) type 2 galanin receptor binding(GO:0031765) type 3 galanin receptor binding(GO:0031766)
2.0 231.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
2.0 14.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
2.0 41.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
2.0 15.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.9 19.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
1.9 5.6 GO:0047708 biotinidase activity(GO:0047708)
1.8 5.4 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
1.8 23.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
1.8 7.0 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
1.7 39.1 GO:0017127 cholesterol transporter activity(GO:0017127)
1.7 5.0 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.6 27.1 GO:0004806 triglyceride lipase activity(GO:0004806)
1.6 7.9 GO:0032767 copper-dependent protein binding(GO:0032767)
1.6 6.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
1.6 4.7 GO:0001847 opsonin receptor activity(GO:0001847)
1.5 9.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.5 3.1 GO:0031762 follicle-stimulating hormone receptor binding(GO:0031762)
1.5 29.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.4 5.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.4 14.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
1.4 7.1 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
1.4 4.2 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.3 6.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.3 7.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.3 5.0 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829)
1.3 11.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.2 34.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.2 15.6 GO:0098879 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
1.2 22.6 GO:0070402 NADPH binding(GO:0070402)
1.1 5.7 GO:0042289 MHC class II protein binding(GO:0042289)
1.1 35.6 GO:0004623 phospholipase A2 activity(GO:0004623)
1.1 12.1 GO:0008131 primary amine oxidase activity(GO:0008131)
1.1 15.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.1 3.2 GO:0034186 apolipoprotein A-I binding(GO:0034186) high-density lipoprotein particle receptor activity(GO:0070506)
1.1 15.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.0 4.2 GO:0004945 angiotensin type II receptor activity(GO:0004945)
1.0 22.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
1.0 3.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
1.0 3.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.9 11.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.9 44.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.9 3.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.9 31.5 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.9 8.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.9 2.6 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.8 5.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.8 5.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.8 2.3 GO:0071209 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.8 6.1 GO:0043495 protein anchor(GO:0043495)
0.8 17.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.7 11.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.7 8.5 GO:0016004 phospholipase activator activity(GO:0016004)
0.7 4.2 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.7 11.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.7 6.9 GO:0042301 phosphate ion binding(GO:0042301)
0.6 142.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.6 7.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.6 2.9 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.6 4.6 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.6 9.0 GO:0035497 cAMP response element binding(GO:0035497)
0.6 8.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.6 1.7 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.5 3.8 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.5 31.6 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.5 12.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.5 9.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.4 2.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.4 1.7 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 7.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.4 1.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.4 3.9 GO:0070513 death domain binding(GO:0070513)
0.4 17.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.3 2.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 11.2 GO:0050699 WW domain binding(GO:0050699)
0.3 3.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 6.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.3 39.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.3 1.5 GO:0048019 receptor antagonist activity(GO:0048019)
0.3 3.0 GO:0019808 polyamine binding(GO:0019808)
0.3 381.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.3 24.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.3 4.9 GO:0008301 DNA binding, bending(GO:0008301)
0.3 1.6 GO:0017040 ceramidase activity(GO:0017040)
0.2 6.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 1.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 3.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 1.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 2.2 GO:0070878 primary miRNA binding(GO:0070878)
0.2 2.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 3.1 GO:0015250 water channel activity(GO:0015250)
0.2 3.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 16.7 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2 3.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.2 23.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 6.6 GO:0004601 peroxidase activity(GO:0004601)
0.2 3.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 1.1 GO:0034235 GPI-anchor transamidase activity(GO:0003923) GPI anchor binding(GO:0034235)
0.2 2.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 3.6 GO:0031005 filamin binding(GO:0031005)
0.2 3.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 5.4 GO:0042605 peptide antigen binding(GO:0042605)
0.2 23.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 0.5 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.2 2.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 4.6 GO:0043531 ADP binding(GO:0043531)
0.2 4.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 5.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 5.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 5.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 6.6 GO:0009055 electron carrier activity(GO:0009055)
0.1 3.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 3.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 7.6 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 1.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 6.7 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 1.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.7 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 1.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 2.1 GO:0043394 proteoglycan binding(GO:0043394)
0.1 5.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 6.5 GO:0002020 protease binding(GO:0002020)
0.1 1.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.6 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 10.7 GO:0005179 hormone activity(GO:0005179)
0.1 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 7.8 GO:0016853 isomerase activity(GO:0016853)
0.1 13.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 2.2 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1 11.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 2.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.6 GO:0051087 chaperone binding(GO:0051087)
0.0 1.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.0 GO:0046332 SMAD binding(GO:0046332)
0.0 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.7 GO:0019843 rRNA binding(GO:0019843)
0.0 6.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 377.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
1.5 82.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.9 9.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.9 21.1 PID IL1 PATHWAY IL1-mediated signaling events
0.7 35.9 NABA COLLAGENS Genes encoding collagen proteins
0.7 61.3 PID CMYB PATHWAY C-MYB transcription factor network
0.6 49.3 PID BCR 5PATHWAY BCR signaling pathway
0.6 11.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.6 8.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.6 9.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.5 14.6 PID CONE PATHWAY Visual signal transduction: Cones
0.5 76.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4 3.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.4 89.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 6.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 15.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 4.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 5.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 15.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 4.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 3.2 PID IL27 PATHWAY IL27-mediated signaling events
0.1 5.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 2.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 133.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
7.3 65.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
5.3 63.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
5.1 51.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
5.0 85.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
4.9 44.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
4.8 62.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
4.8 138.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
3.0 27.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
2.8 139.3 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
2.4 12.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
2.1 39.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
2.0 13.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
1.9 75.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
1.8 27.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.8 1.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
1.4 53.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
1.4 11.0 REACTOME DEFENSINS Genes involved in Defensins
1.3 36.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
1.1 19.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
1.1 14.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.0 34.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.9 138.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.9 13.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.8 5.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.7 8.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.7 42.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.7 36.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.7 9.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.7 12.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.6 6.8 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.6 8.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.6 17.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.5 15.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.4 13.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.4 6.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.4 7.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.4 25.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.3 14.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.3 7.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 16.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 6.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 2.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 8.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 3.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 6.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 1.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 0.9 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.2 4.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 6.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 13.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.0 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 3.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 3.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 5.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.7 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation