Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Zfp423

Z-value: 0.44

Motif logo

logo of

Transcription factors associated with Zfp423

Gene Symbol Gene ID Gene Info
Zfp423
ENSRNOG00000014658 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp423rn6_v1_chr19_+_20147037_201470370.254.3e-06Click!

Activity profile of Zfp423 motif

Sorted Z-values of Zfp423 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_142453013 21.13 ENSRNOT00000056573
AABR07061755.1

chr1_-_226152524 15.90 ENSRNOT00000027756
Fads2
fatty acid desaturase 2
chr6_-_39363367 13.60 ENSRNOT00000088687
ENSRNOT00000065531
Fam84a
family with sequence similarity 84, member A
chr1_-_70235091 12.54 ENSRNOT00000075745
Apeg3
antisense paternally expressed gene 3
chr3_+_56868167 9.93 ENSRNOT00000087134
Gad1
glutamate decarboxylase 1
chr13_-_90710148 9.56 ENSRNOT00000010113
ENSRNOT00000080638
Kcnj9
potassium voltage-gated channel subfamily J member 9
chr12_-_47793534 8.50 ENSRNOT00000001588
Fam222a
family with sequence similarity 222, member A
chr1_-_226924244 7.33 ENSRNOT00000028971
Tmem132a
transmembrane protein 132A
chr7_-_107009330 6.83 ENSRNOT00000074573
Kcnq3
potassium voltage-gated channel subfamily Q member 3
chr15_-_28733513 6.17 ENSRNOT00000078180
Sall2
spalt-like transcription factor 2
chr1_+_224800252 6.11 ENSRNOT00000024488
Slc22a8
solute carrier family 22 member 8
chr7_-_124041594 5.95 ENSRNOT00000064700
Cyb5r3
cytochrome b5 reductase 3
chr10_+_80790168 5.74 ENSRNOT00000073315
ENSRNOT00000075163
Car10
carbonic anhydrase 10
chr1_+_87248489 5.72 ENSRNOT00000028091
Dpf1
double PHD fingers 1
chr6_-_44361908 5.31 ENSRNOT00000009491
Id2
inhibitor of DNA binding 2, HLH protein
chr1_+_100224401 4.88 ENSRNOT00000025846
Fv1
Friend virus susceptibility 1
chr1_-_170464341 4.10 ENSRNOT00000024850
Trim3
tripartite motif-containing 3
chr9_+_117538346 4.01 ENSRNOT00000022849
Epb41l3
erythrocyte membrane protein band 4.1-like 3
chr7_+_120067379 3.96 ENSRNOT00000011270
Cdc42ep1
CDC42 effector protein 1
chr1_+_101688297 3.80 ENSRNOT00000091606
Dbp
D-box binding PAR bZIP transcription factor
chr4_+_7282948 3.40 ENSRNOT00000011052
Cdk5
cyclin-dependent kinase 5
chr1_+_266953139 3.35 ENSRNOT00000054696
Neurl1
neuralized E3 ubiquitin protein ligase 1
chr4_+_32373641 2.76 ENSRNOT00000076086
Dlx6
distal-less homeobox 6
chr5_+_172648950 2.74 ENSRNOT00000055361
Faap20
Fanconi anemia core complex associated protein 20
chr1_-_131454689 2.71 ENSRNOT00000014152
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr7_-_70926903 2.68 ENSRNOT00000031005
Lrp1
LDL receptor related protein 1
chr4_-_157009674 2.55 ENSRNOT00000071625
Pex5
peroxisomal biogenesis factor 5
chr4_-_156427755 2.55 ENSRNOT00000085675
ENSRNOT00000014030
LOC103690024
peroxisomal targeting signal 1 receptor-like
chr4_-_157008947 2.47 ENSRNOT00000073341
Pex5
peroxisomal biogenesis factor 5
chr2_-_48501436 2.40 ENSRNOT00000017305
Isl1
ISL LIM homeobox 1
chr11_+_86890585 1.83 ENSRNOT00000002579
Ranbp1
RAN binding protein 1
chr1_-_259484569 1.81 ENSRNOT00000021289
ENSRNOT00000021114
ENSRNOT00000021229
ENSRNOT00000021347
ENSRNOT00000021226
Sorbs1
sorbin and SH3 domain containing 1
chr1_-_198316882 1.51 ENSRNOT00000085304
ENSRNOT00000064985
Taok2
TAO kinase 2
chr19_+_43163129 1.40 ENSRNOT00000073721
Clec18a
C-type lectin domain family 18, member A
chr3_+_161252723 1.29 ENSRNOT00000084283
Snx21
sorting nexin family member 21
chr5_+_138279506 0.98 ENSRNOT00000084651
P3h1
prolyl 3-hydroxylase 1
chr13_+_51384562 0.97 ENSRNOT00000077928
Kdm5b
lysine demethylase 5B
chr2_-_61949926 0.96 ENSRNOT00000025966
Npr3
natriuretic peptide receptor 3
chr7_+_130532435 0.92 ENSRNOT00000092672
ENSRNOT00000092535
Shank3
SH3 and multiple ankyrin repeat domains 3
chr10_-_18131562 0.86 ENSRNOT00000006676
Tlx3
T-cell leukemia, homeobox 3
chrX_+_140878216 0.84 ENSRNOT00000075840
ENSRNOT00000077026
Zic3
Zic family member 3
chr8_+_82038967 0.70 ENSRNOT00000079535
Myo5a
myosin VA
chr17_-_21353134 0.68 ENSRNOT00000067898
Smim13
small integral membrane protein 13
chr5_-_138279285 0.66 ENSRNOT00000009044
RGD1564804
similar to chromosome 1 open reading frame 50
chr9_+_94178221 0.63 ENSRNOT00000033487
Alppl2
alkaline phosphatase, placental-like 2
chr13_+_51384389 0.62 ENSRNOT00000087025
Kdm5b
lysine demethylase 5B
chr3_-_122920684 0.61 ENSRNOT00000028818
Cpxm1
carboxypeptidase X (M14 family), member 1
chr7_-_144960527 0.56 ENSRNOT00000086554
Zfp385a
zinc finger protein 385A
chr19_-_11057254 0.41 ENSRNOT00000025559
Herpud1
homocysteine inducible ER protein with ubiquitin like domain 1
chr2_-_210413985 0.30 ENSRNOT00000025036
Strip1
striatin interacting protein 1
chr11_-_86890390 0.29 ENSRNOT00000046183
Trmt2a
tRNA methyltransferase 2 homolog A
chr5_-_171312026 0.25 ENSRNOT00000063779
Smim1
small integral membrane protein 1
chr1_-_8878136 0.04 ENSRNOT00000064836
ENSRNOT00000075850
Vta1
vesicle trafficking 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp423

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
2.0 9.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.8 5.3 GO:0001966 thigmotaxis(GO:0001966)
1.1 7.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.9 15.9 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.9 2.7 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.8 2.4 GO:0071657 visceral motor neuron differentiation(GO:0021524) sensory system development(GO:0048880) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.7 2.7 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.7 4.0 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.6 1.8 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.4 1.6 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.4 3.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.4 1.8 GO:1904008 response to monosodium glutamate(GO:1904008)
0.3 1.0 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.3 6.8 GO:0061548 membrane hyperpolarization(GO:0060081) ganglion development(GO:0061548)
0.3 9.6 GO:0010107 potassium ion import(GO:0010107)
0.3 4.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 4.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2 2.7 GO:0019985 translesion synthesis(GO:0019985)
0.2 0.7 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.6 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 5.9 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.1 0.8 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 1.0 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.9 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 2.8 GO:0060021 palate development(GO:0060021)
0.0 1.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 6.2 GO:0001654 eye development(GO:0001654)
0.0 3.8 GO:0001889 liver development(GO:0001889)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.6 1.8 GO:0005899 insulin receptor complex(GO:0005899)
0.4 5.7 GO:0071565 nBAF complex(GO:0071565)
0.3 6.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 4.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 6.8 GO:0033268 node of Ranvier(GO:0033268)
0.3 9.9 GO:0060077 inhibitory synapse(GO:0060077)
0.2 0.7 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.2 2.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 2.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 3.3 GO:0097440 apical dendrite(GO:0097440)
0.1 5.0 GO:0044439 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1 5.9 GO:0005811 lipid particle(GO:0005811)
0.0 1.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 4.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 6.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.1 GO:0005769 early endosome(GO:0005769)
0.0 18.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.9 GO:0060170 ciliary membrane(GO:0060170)
0.0 10.4 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 15.9 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
2.0 9.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.9 9.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.5 7.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
1.0 5.9 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.8 6.1 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.7 3.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 1.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.3 1.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 1.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 4.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 2.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 2.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 2.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 2.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 3.3 GO:0045182 translation regulator activity(GO:0045182)
0.1 1.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 11.5 GO:0044325 ion channel binding(GO:0044325)
0.1 1.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 4.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 4.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 5.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.8 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 15.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.6 6.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.4 9.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 9.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 6.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 3.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 2.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 5.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 3.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.8 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4