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Results for AZF1

Z-value: 2.59

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Transcription factors associated with AZF1

Gene Symbol Gene ID Gene Info
AZF1
S000005639 Zinc-finger transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
AZF1YOR113W-0.367.5e-02Click!

Activity profile of AZF1 motif

Sorted Z-values of AZF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YFR055W 62.25
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YFR056C 53.57 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YIL053W 28.03
RHR2
Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress
YPR119W 26.16
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YDR033W 24.84
MRH1
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p
YDR044W 23.10
HEM13
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
YHR094C 22.40
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YDL055C 20.74
PSA1
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure
YJR094W-A 20.17
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YMR290W-A 19.64 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YMR290C 19.15
HAS1
ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles
YFR054C 18.57 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YKL182W 16.65
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YGR108W 16.55
CLB1
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YIR021W 16.33
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YJL115W 15.19
ASF1
Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition
YOL124C 14.59
TRM11
Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain
YKL218C 14.53
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YOR101W 14.47
RAS1
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes
YAL003W 14.08
EFB1
Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site
YOR315W 13.72
SFG1
Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate
YNL178W 13.61
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YMR011W 13.13
HXT2
High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose
YDR509W 13.11 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YLR154C 13.06
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YIL118W 12.90
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YDR508C 12.83
GNP1
High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids
YGL148W 12.58
ARO2
Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids
YLR154W-A 12.53 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YMR296C 11.97
LCB1
Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine
YKL110C 11.71
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YAL038W 11.54
CDC19
Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
YLR154W-B 11.53 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR150W 11.37
STM1
Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations
YMR083W 11.31
ADH3
Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production
YBR158W 11.27
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YNR013C 11.17
PHO91
Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YOR107W 10.81
RGS2
Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p
YCR018C 10.57
SRD1
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
YDL211C 10.54 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
YKR092C 10.44
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YIL056W 10.22
VHR1
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations
YPL037C 10.19
EGD1
Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b
YOL123W 9.83
HRP1
Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences
YGR052W 9.82
FMP48
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation
YDL022C-A 9.73 Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene DIA3; identified by fungal homology and RT-PCR
YGL179C 9.63
TOS3
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
YBR106W 9.60
PHO88
Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations
YKR075C 9.59 Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YEL068C 9.42 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGR050C 9.40 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPR010C 9.25
RPA135
RNA polymerase I subunit A135
YJR145C 9.23
RPS4A
Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
YDL047W 9.22
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YMR217W 9.20
GUA1
GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation
YHR127W 9.17 Protein of unknown function; localizes to the nucleus
YLR432W 9.16
IMD3
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed
YOL086C 9.15
ADH1
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
YDL023C 9.12 Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance
YMR049C 9.05
ERB1
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
YDR279W 8.96
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YDR098C 8.80
GRX3
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
YMR102C 8.78 Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
YNL112W 8.54
DBP2
Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing
YKL164C 8.45
PIR1
O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle
YML043C 8.42
RRN11
Protein required for rDNA transcription by RNA polymerase I, component of the core factor (CF) of rDNA transcription factor, which also contains Rrn6p and Rrn7p
YLR249W 8.41
YEF3
Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP
YGR051C 8.32 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene
YEL029C 8.30
BUD16
Putative pyridoxal kinase, key enzyme in vitamin B6 metabolism; involved in maintaining levels of pyridoxal 5'-phosphate, the active form of vitamin B6; required for genome integrity; homolog of E. coli PdxK; involved in bud-site selection
YBR112C 8.26
CYC8
General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters
YPR157W 8.25 Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation
YJR123W 8.19
RPS5
Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins
YOR376W-A 8.09 Putative protein of unknown function; identified by fungal homology and RT-PCR
YHR010W 8.05
RPL27A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein
YOR355W 7.95
GDS1
Protein of unknown function, required for growth on glycerol as a carbon source; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YLR154W-C 7.92
TAR1
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
YNL065W 7.91
AQR1
Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids
YFR031C-A 7.85
RPL2A
Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins
YNL141W 7.79
AAH1
Adenine deaminase (adenine aminohydrolase), converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome
YDR037W 7.75
KRS1
Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis
YGR152C 7.69
RSR1
GTP-binding protein of the ras superfamily required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases
YLR449W 7.68
FPR4
Peptidyl-prolyl cis-trans isomerase (PPIase) (proline isomerase) localized to the nucleus; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones
YFR032C 7.67 Putative protein of unknown function; transcribed during sporulation; YFR032C is not an essential gene
YDL075W 7.66
RPL31A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YOR375C 7.65
GDH1
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources
YJL158C 7.64
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
YLL045C 7.61
RPL8B
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
YDL022W 7.61
GPD1
NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
YGR176W 7.58 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDR344C 7.58 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YER131W 7.46
RPS26B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
YEL027W 7.43
CUP5
Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide binding subunit); required for vacuolar acidification and important for copper and iron metal ion homeostasis
YLR413W 7.37 Putative protein of unknown function; YLR413W is not an essential gene
YBR238C 7.33 Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span
YER137C 7.32 Putative protein of unknown function
YGR060W 7.31
ERG25
C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol
YER001W 7.23
MNN1
Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family
YPR008W 7.20
HAA1
Transcriptional activator involved in the transcription of TPO2, HSP30 and other genes encoding membrane stress proteins; involved in adaptation to weak acid stress
YPR148C 7.20 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YDR041W 7.17
RSM10
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins
YPL198W 7.16
RPL7B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)
YGL097W 7.15
SRM1
Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p
YFL015W-A 7.12 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YBR113W 7.10 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CYC8
YNR001W-A 7.08 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YKL063C 7.06 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
YDR094W 7.06 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2
YDR471W 7.02
RPL27B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Ap and has similarity to rat L27 ribosomal protein
YER177W 6.97
BMH1
14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling
YGR229C 6.91
SMI1
Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity
YDR040C 6.87
ENA1
P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
YNL066W 6.82
SUN4
Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family
YBL092W 6.77
RPL32
Protein component of the large (60S) ribosomal subunit, has similarity to rat L32 ribosomal protein; overexpression disrupts telomeric silencing
YHR216W 6.76
IMD2
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
YHR201C 6.74
PPX1
Exopolyphosphatase, hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix
YLR075W 6.71
RPL10
Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family
YGR040W 6.66
KSS1
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
YOL155C 6.66
HPF1
Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines
YHR181W 6.63
SVP26
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment
YIL158W 6.62
AIM20
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
YLR018C 6.61
POM34
Integral membrane protein of the nuclear pore; has an important role in maintaining the architecture of the pore complex
YJL107C 6.60 Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi
YCR031C 6.60
RPS14A
Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins
YKR038C 6.57
KAE1
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
YML063W 6.55
RPS1B
Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein
YOR234C 6.52
RPL33B
Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable
YER074W 6.52
RPS24A
Protein component of the small (40S) ribosomal subunit; identical to Rps24Bp and has similarity to rat S24 ribosomal protein
YLR076C 6.49 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the essential gene RPL10 which encodes the ribosomal protein L10
YEL001C 6.49
IRC22
Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci
YGR085C 6.46
RPL11B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Ap; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11
YFL015C 6.40 Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene
YDR345C 6.40
HXT3
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
YOR063W 6.31
RPL3
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
YDR002W 6.24
YRB1
Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1
YDL241W 6.20 Putative protein of unknown function; YDL241W is not an essential gene
YEL067C 6.13 Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YOR047C 6.09
STD1
Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p
YEL053W-A 6.08 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YEL054C
YDR095C 6.08 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YLL012W 6.07
YEH1
Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes
YPR163C 6.07
TIF3
Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif and binds to single-stranded RNA
YGL039W 6.01 Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)
YEL066W 5.97
HPA3
D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro
YJL105W 5.91
SET4
Protein of unknown function, contains a SET domain
YKL219W 5.88
COS9
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
YDL101C 5.85
DUN1
Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair
YJL177W 5.84
RPL17B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins
YER043C 5.83
SAH1
S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor
YLL028W 5.82
TPO1
Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane
YNL189W 5.80
SRP1
Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation
YIL009W 5.78
FAA3
Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YCL024W 5.75
KCC4
Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p
YEL056W 5.73
HAT2
Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing
YGL189C 5.68
RPS26A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Bp and has similarity to rat S26 ribosomal protein
YBR087W 5.64
RFC5
Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
YML075C 5.63
HMG1
One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae
YER073W 5.61
ALD5
Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed
YBL085W 5.57
BOI1
Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
YOR313C 5.55
SPS4
Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage
YER045C 5.49
ACA1
Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources
YOR029W 5.48 Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data
YJL153C 5.47
INO1
Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
YPR063C 5.45 ER-localized protein of unknown function
YOR050C 5.45 Hypothetical protein
YOR051C 5.44 Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
YGR195W 5.39
SKI6
3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs
YDR101C 5.36
ARX1
Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit biogenesis; interacts directly with Alb1; responsible for Tif6 recycling defects in absence of Rei1; associated with the ribosomal export complex
YER046W 5.33
SPO73
Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensible for both nuclear divisions during meiosis
YJL106W 5.31
IME2
Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p
YOR314W 5.28 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YOL127W 5.27
RPL25
Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif
YGR242W 5.26 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C
YER049W 5.25
TPA1
Protein of unknown function; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; has a role in translation termination efficiency, mRNA poly(A) tail length and mRNA stability
YMR006C 5.24
PLB2
Phospholipase B (lysophospholipase) involved in phospholipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine
YLR110C 5.23
CCW12
Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor
YLR022C 5.20
SDO1
Essential protein involved in 60S ribosome maturation; ortholog of the human protein (SBDS) responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome; highly conserved across archae and eukaryotes
YNR054C 5.19
ESF2
Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome
YOR342C 5.12 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus
YNL114C 5.09 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF RPC19/YNL113W, an RNA polymerase subunit
YNR016C 5.08
ACC1
Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids
YKL096W-A 5.06
CWP2
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored
YEL033W 5.05
MTC7
Predicted metabolic role based on network analysis derived from ChIP experiments, a large-scale deletion study and localization of transcription factor binding sites; null mutant is sensitive to temperature oscillation in a cdc13-1 mutant
YOR028C 4.95
CIN5
Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus
YGR090W 4.94
UTP22
Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
YPL062W 4.92 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation
YLL044W 4.92 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLL044W and the overlapping gene RPL8B is reduced in the gcr1 null mutant
YDL048C 4.89
STP4
Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p
YGR140W 4.84
CBF2
Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
YKL030W 4.84 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene MAE1
YOR008C-A 4.82 Putative protein of unknown function, includes a potential transmembrane domain; deletion results in slightly lengthened telomeres
YLR190W 4.81
MMR1
Phosphorylated protein of the mitochondrial outer membrane, localizes only to mitochondria of the bud; interacts with Myo2p to mediate mitochondrial distribution to buds; mRNA is targeted to the bud via the transport system involving She2p
YNR072W 4.81
HXT17
Hexose transporter, up-regulated in media containing raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose
YKR013W 4.81
PRY2
Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins
YCL023C 4.79 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF KCC4
YBR092C 4.76
PHO3
Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin
YER124C 4.73
DSE1
Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall
YPR014C 4.69 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPR014C is not an essential gene
YNL113W 4.68
RPC19
RNA polymerase subunit, common to RNA polymerases I and III
YMR037C 4.66
MSN2
Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
YOR293W 4.66
RPS10A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Bp and has similarity to rat ribosomal protein S10

Network of associatons between targets according to the STRING database.

First level regulatory network of AZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
20.4 61.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
9.6 28.8 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
7.8 23.5 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
6.6 46.3 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
6.3 31.5 GO:0006177 GMP biosynthetic process(GO:0006177)
5.9 17.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
4.8 9.6 GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187) adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
4.6 18.3 GO:0009423 chorismate biosynthetic process(GO:0009423)
4.3 13.0 GO:0035952 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
4.2 29.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
3.7 25.7 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
3.6 10.9 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
3.6 3.6 GO:0046898 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
3.6 10.7 GO:0043069 negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069) negative regulation of cell death(GO:0060548)
3.4 17.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
3.3 16.6 GO:0051046 regulation of exocytosis(GO:0017157) regulation of secretion(GO:0051046) regulation of secretion by cell(GO:1903530)
3.3 16.5 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
3.3 58.6 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
3.0 12.2 GO:0000296 spermine transport(GO:0000296)
2.7 27.5 GO:0006797 polyphosphate metabolic process(GO:0006797)
2.7 8.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
2.6 13.2 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
2.6 7.9 GO:0046083 adenine metabolic process(GO:0046083)
2.6 10.3 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
2.6 7.7 GO:0009176 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
2.6 10.3 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
2.5 7.6 GO:0046495 nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637)
2.4 4.8 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
2.4 7.2 GO:0045901 positive regulation of translational elongation(GO:0045901)
2.4 9.5 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
2.3 6.8 GO:1900062 regulation of cell aging(GO:0090342) regulation of replicative cell aging(GO:1900062)
2.2 313.5 GO:0002181 cytoplasmic translation(GO:0002181)
2.2 21.9 GO:0006116 NADH oxidation(GO:0006116)
2.1 4.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
2.1 6.3 GO:0043171 peptide catabolic process(GO:0043171)
2.1 2.1 GO:0033239 negative regulation of cellular amine metabolic process(GO:0033239)
2.1 8.3 GO:0031057 negative regulation of histone modification(GO:0031057)
2.0 2.0 GO:0046417 chorismate metabolic process(GO:0046417)
2.0 5.9 GO:0006567 threonine catabolic process(GO:0006567)
1.9 17.5 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
1.9 5.8 GO:0046677 response to antibiotic(GO:0046677)
1.9 9.5 GO:0007535 donor selection(GO:0007535)
1.9 7.6 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
1.9 9.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
1.9 5.7 GO:0046416 D-amino acid metabolic process(GO:0046416)
1.9 1.9 GO:0046037 GMP metabolic process(GO:0046037)
1.9 7.4 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
1.8 7.4 GO:0098740 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
1.8 14.6 GO:0000376 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
1.8 7.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
1.8 5.3 GO:0034310 ethanol catabolic process(GO:0006068) acetate biosynthetic process(GO:0019413) primary alcohol catabolic process(GO:0034310)
1.7 19.0 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
1.7 5.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
1.7 20.1 GO:0006415 translational termination(GO:0006415)
1.7 25.1 GO:0071047 nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
1.7 6.7 GO:0042256 mature ribosome assembly(GO:0042256)
1.7 1.7 GO:0071482 cellular response to radiation(GO:0071478) cellular response to light stimulus(GO:0071482)
1.7 9.9 GO:0007329 positive regulation of transcription from RNA polymerase II promoter by pheromones(GO:0007329) positive regulation of transcription by pheromones(GO:0009371)
1.6 6.5 GO:0006021 inositol biosynthetic process(GO:0006021)
1.5 9.3 GO:0009099 valine biosynthetic process(GO:0009099)
1.5 6.2 GO:0030497 fatty acid elongation(GO:0030497)
1.5 4.4 GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
1.5 5.8 GO:0036170 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
1.4 4.3 GO:1902931 negative regulation of alcohol biosynthetic process(GO:1902931)
1.4 5.7 GO:0009090 homoserine biosynthetic process(GO:0009090)
1.4 5.7 GO:0042990 regulation of transcription factor import into nucleus(GO:0042990)
1.4 4.2 GO:0018195 peptidyl-arginine modification(GO:0018195) peptidyl-arginine methylation(GO:0018216)
1.4 6.9 GO:1903338 regulation of cell wall organization or biogenesis(GO:1903338)
1.4 8.2 GO:0006491 N-glycan processing(GO:0006491)
1.4 4.1 GO:0032006 regulation of TOR signaling(GO:0032006)
1.4 1.4 GO:0071902 positive regulation of protein serine/threonine kinase activity(GO:0071902)
1.3 6.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.3 9.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.3 6.7 GO:0042780 tRNA 3'-end processing(GO:0042780)
1.3 6.6 GO:0090158 regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158)
1.3 3.9 GO:0048194 Golgi vesicle budding(GO:0048194)
1.3 15.2 GO:0007120 axial cellular bud site selection(GO:0007120)
1.3 12.5 GO:0006272 leading strand elongation(GO:0006272)
1.2 26.2 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
1.2 2.5 GO:0070814 hydrogen sulfide metabolic process(GO:0070813) hydrogen sulfide biosynthetic process(GO:0070814)
1.2 17.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
1.2 4.8 GO:0045947 negative regulation of translational initiation(GO:0045947)
1.2 6.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
1.2 7.2 GO:0043489 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
1.2 8.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
1.2 21.3 GO:0030488 tRNA methylation(GO:0030488)
1.2 8.2 GO:0034501 protein localization to kinetochore(GO:0034501)
1.2 1.2 GO:0034471 rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
1.1 2.2 GO:0036213 actomyosin contractile ring contraction(GO:0000916) contractile ring contraction(GO:0036213)
1.1 5.5 GO:0000162 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
1.1 8.7 GO:0001402 signal transduction involved in filamentous growth(GO:0001402)
1.1 6.5 GO:0034063 stress granule assembly(GO:0034063)
1.1 8.6 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
1.1 2.1 GO:0031384 regulation of initiation of mating projection growth(GO:0031384)
1.0 10.5 GO:0007021 tubulin complex assembly(GO:0007021)
1.0 3.1 GO:0000092 mitotic anaphase B(GO:0000092)
1.0 19.6 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.0 24.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
1.0 14.3 GO:0001100 negative regulation of exit from mitosis(GO:0001100)
1.0 1.0 GO:0032186 cellular bud neck septin ring organization(GO:0032186)
1.0 5.1 GO:0046656 folic acid metabolic process(GO:0046655) folic acid biosynthetic process(GO:0046656)
1.0 25.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
1.0 18.0 GO:0042797 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.0 3.9 GO:0015883 FAD transport(GO:0015883)
1.0 21.3 GO:0006633 fatty acid biosynthetic process(GO:0006633)
1.0 4.8 GO:0051125 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) regulation of actin nucleation(GO:0051125)
0.9 5.6 GO:0048478 replication fork protection(GO:0048478)
0.9 13.0 GO:0010383 cell wall polysaccharide metabolic process(GO:0010383)
0.9 5.6 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.9 6.5 GO:0006855 drug transmembrane transport(GO:0006855)
0.9 3.7 GO:0090220 meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.9 2.8 GO:0015693 magnesium ion transport(GO:0015693)
0.9 4.6 GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay(GO:0070481)
0.9 4.5 GO:0006110 regulation of glycolytic process(GO:0006110)
0.9 0.9 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.9 3.5 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.9 7.8 GO:0006817 phosphate ion transport(GO:0006817)
0.9 0.9 GO:1902223 L-phenylalanine biosynthetic process(GO:0009094) erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process(GO:1902223)
0.8 6.8 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.8 8.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.8 27.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.8 23.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.8 2.5 GO:1900101 regulation of endoplasmic reticulum unfolded protein response(GO:1900101)
0.8 3.3 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.8 11.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.8 4.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.8 3.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.8 4.8 GO:0019933 cAMP-mediated signaling(GO:0019933) cyclic-nucleotide-mediated signaling(GO:0019935)
0.8 3.1 GO:0051597 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.8 0.8 GO:0043065 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.8 2.3 GO:1901976 regulation of cell cycle checkpoint(GO:1901976) negative regulation of cell cycle checkpoint(GO:1901977) regulation of DNA damage checkpoint(GO:2000001) negative regulation of DNA damage checkpoint(GO:2000002) negative regulation of response to DNA damage stimulus(GO:2001021)
0.7 11.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.7 2.2 GO:0034517 ribophagy(GO:0034517)
0.7 1.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.7 2.2 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.7 2.9 GO:0015809 arginine transport(GO:0015809)
0.7 1.4 GO:0007050 cell cycle arrest(GO:0007050)
0.7 10.6 GO:0043094 cellular metabolic compound salvage(GO:0043094)
0.7 3.5 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.7 7.0 GO:0016574 histone ubiquitination(GO:0016574)
0.7 4.9 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.7 1.4 GO:0000080 mitotic G1 phase(GO:0000080) G1 phase(GO:0051318)
0.7 0.7 GO:1901352 regulation of phosphatidylglycerol biosynthetic process(GO:1901351) negative regulation of phosphatidylglycerol biosynthetic process(GO:1901352)
0.7 6.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.7 24.5 GO:1902593 protein import into nucleus(GO:0006606) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593)
0.7 14.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
0.7 7.4 GO:0032508 DNA duplex unwinding(GO:0032508)
0.7 1.3 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111) regulation of microtubule depolymerization(GO:0031114)
0.7 2.0 GO:0000101 sulfur amino acid transport(GO:0000101)
0.7 1.3 GO:0070868 heterochromatin organization involved in chromatin silencing(GO:0070868) chromatin organization involved in negative regulation of transcription(GO:0097549)
0.7 3.3 GO:0033313 meiotic cell cycle checkpoint(GO:0033313) meiotic recombination checkpoint(GO:0051598)
0.6 7.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.6 1.9 GO:1902707 glucose catabolic process(GO:0006007) glycolytic fermentation to ethanol(GO:0019655) glycolytic fermentation(GO:0019660) hexose catabolic process to ethanol(GO:1902707)
0.6 1.2 GO:0006734 NADH metabolic process(GO:0006734)
0.6 1.2 GO:0031684 heterotrimeric G-protein complex cycle(GO:0031684)
0.6 3.7 GO:0030042 actin filament depolymerization(GO:0030042)
0.6 1.8 GO:0009164 nucleoside catabolic process(GO:0009164) glycosyl compound catabolic process(GO:1901658)
0.6 1.8 GO:0090527 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.6 17.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.6 11.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.6 1.7 GO:0016584 nucleosome positioning(GO:0016584)
0.6 56.9 GO:0006364 rRNA processing(GO:0006364)
0.6 0.6 GO:0007232 osmosensory signaling pathway via Sho1 osmosensor(GO:0007232)
0.6 2.9 GO:0043007 maintenance of rDNA(GO:0043007)
0.6 3.4 GO:0007030 Golgi organization(GO:0007030)
0.6 2.8 GO:0035376 sterol import(GO:0035376)
0.6 2.3 GO:0061572 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.6 1.7 GO:0008272 sulfate transport(GO:0008272)
0.6 8.3 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.5 1.1 GO:0000433 negative regulation of transcription from RNA polymerase II promoter by glucose(GO:0000433) negative regulation of transcription by glucose(GO:0045014)
0.5 3.8 GO:0007009 plasma membrane organization(GO:0007009)
0.5 2.1 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.5 6.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.5 1.6 GO:0051668 localization within membrane(GO:0051668)
0.5 2.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.5 1.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.5 4.7 GO:0000917 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529)
0.5 4.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.5 1.0 GO:0030541 plasmid partitioning(GO:0030541)
0.5 7.6 GO:0000011 vacuole inheritance(GO:0000011)
0.5 2.0 GO:0030030 cell projection organization(GO:0030030) cell projection assembly(GO:0030031)
0.5 1.9 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.5 1.4 GO:0006566 threonine metabolic process(GO:0006566)
0.5 0.5 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.5 1.4 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.5 2.8 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.5 6.5 GO:0016125 steroid metabolic process(GO:0008202) sterol metabolic process(GO:0016125)
0.5 0.5 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.5 0.9 GO:0034059 response to anoxia(GO:0034059) cellular response to anoxia(GO:0071454)
0.5 10.6 GO:0045047 protein targeting to ER(GO:0045047)
0.5 4.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.4 4.5 GO:0009303 rRNA transcription(GO:0009303)
0.4 4.9 GO:0030011 maintenance of cell polarity(GO:0030011)
0.4 4.0 GO:0000105 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.4 0.9 GO:0000957 mitochondrial RNA catabolic process(GO:0000957)
0.4 2.6 GO:0070941 eisosome assembly(GO:0070941)
0.4 1.7 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.4 3.0 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.4 4.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.4 1.3 GO:0044070 regulation of anion transport(GO:0044070)
0.4 7.7 GO:0006414 translational elongation(GO:0006414)
0.4 1.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.4 0.8 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.4 8.3 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.4 0.8 GO:0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674)
0.4 0.4 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin structure organization(GO:0031032) actomyosin contractile ring organization(GO:0044837)
0.4 0.8 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.4 6.5 GO:0000096 sulfur amino acid metabolic process(GO:0000096)
0.4 0.8 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.4 0.8 GO:0009847 spore germination(GO:0009847)
0.4 1.5 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.4 3.8 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.4 8.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.4 1.5 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.4 10.8 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.4 2.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.4 1.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.4 2.1 GO:0046040 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.4 5.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.4 0.4 GO:0051093 negative regulation of developmental process(GO:0051093)
0.3 1.4 GO:0045833 negative regulation of lipid metabolic process(GO:0045833)
0.3 18.5 GO:0016311 dephosphorylation(GO:0016311)
0.3 2.7 GO:0015833 peptide transport(GO:0015833)
0.3 1.4 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.3 1.0 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.3 5.6 GO:0006400 tRNA modification(GO:0006400)
0.3 3.2 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.3 0.6 GO:0046136 regulation of vitamin metabolic process(GO:0030656) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of sulfur metabolic process(GO:0051176) regulation of thiamine biosynthetic process(GO:0070623) positive regulation of thiamine biosynthetic process(GO:0090180)
0.3 0.6 GO:0071046 polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.3 0.3 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.3 2.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.3 1.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 1.5 GO:0009306 protein secretion(GO:0009306)
0.3 0.9 GO:0000348 mRNA branch site recognition(GO:0000348)
0.3 7.6 GO:0045859 regulation of protein kinase activity(GO:0045859)
0.3 1.5 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3 0.9 GO:0097502 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.3 0.6 GO:0007234 osmosensory signaling via phosphorelay pathway(GO:0007234)
0.3 0.3 GO:0006952 defense response(GO:0006952)
0.3 0.6 GO:0071027 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027)
0.3 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.3 0.9 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.3 1.7 GO:0051028 mRNA transport(GO:0051028)
0.3 0.3 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.3 0.9 GO:0043937 regulation of sporulation resulting in formation of a cellular spore(GO:0042173) regulation of sporulation(GO:0043937)
0.3 2.0 GO:0005992 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
0.3 1.4 GO:0006874 cellular calcium ion homeostasis(GO:0006874) calcium ion homeostasis(GO:0055074)
0.3 1.4 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.3 2.7 GO:0007020 microtubule nucleation(GO:0007020) microtubule polymerization or depolymerization(GO:0031109) microtubule polymerization(GO:0046785)
0.3 0.8 GO:0045595 positive regulation of cell fate commitment(GO:0010455) positive regulation of mating type switching(GO:0031496) regulation of cell differentiation(GO:0045595) positive regulation of cell differentiation(GO:0045597) positive regulation of developmental process(GO:0051094)
0.3 1.9 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 5.1 GO:0007015 actin filament organization(GO:0007015)
0.3 1.1 GO:0016074 snoRNA metabolic process(GO:0016074)
0.3 0.8 GO:0015886 heme transport(GO:0015886)
0.3 3.2 GO:0008033 tRNA processing(GO:0008033)
0.3 0.5 GO:0006816 calcium ion transport(GO:0006816)
0.3 1.8 GO:0015791 polyol transport(GO:0015791)
0.3 2.9 GO:0006334 nucleosome assembly(GO:0006334)
0.3 0.8 GO:0015867 ATP transport(GO:0015867)
0.3 0.5 GO:0051664 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.2 1.2 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.2 0.2 GO:0006571 tyrosine biosynthetic process(GO:0006571)
0.2 2.2 GO:0006999 nuclear pore organization(GO:0006999)
0.2 1.7 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 6.0 GO:0000910 cytokinesis(GO:0000910)
0.2 0.5 GO:0001109 promoter clearance during DNA-templated transcription(GO:0001109) promoter clearance from RNA polymerase II promoter(GO:0001111)
0.2 5.4 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.2 0.2 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.2 1.2 GO:0051666 actin cortical patch localization(GO:0051666)
0.2 5.8 GO:0006913 nucleocytoplasmic transport(GO:0006913)
0.2 0.9 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.2 5.1 GO:0006413 translational initiation(GO:0006413)
0.2 1.1 GO:0055075 cellular potassium ion homeostasis(GO:0030007) potassium ion homeostasis(GO:0055075)
0.2 3.8 GO:0009267 cellular response to starvation(GO:0009267)
0.2 0.7 GO:0006032 aminoglycan catabolic process(GO:0006026) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.2 0.9 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 0.7 GO:0035753 maintenance of DNA trinucleotide repeats(GO:0035753)
0.2 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.2 0.6 GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148)
0.2 0.2 GO:0006721 terpenoid metabolic process(GO:0006721) terpenoid biosynthetic process(GO:0016114) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
0.2 1.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.2 2.0 GO:0030474 spindle pole body duplication(GO:0030474)
0.2 0.2 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.8 GO:0015680 intracellular copper ion transport(GO:0015680)
0.2 1.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 0.2 GO:0006399 tRNA metabolic process(GO:0006399)
0.2 3.0 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.2 4.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 0.8 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.2 0.7 GO:0019184 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.2 1.6 GO:0000001 mitochondrion inheritance(GO:0000001) mitochondrion distribution(GO:0048311)
0.2 0.7 GO:0007000 nucleolus organization(GO:0007000) rDNA condensation(GO:0070550)
0.2 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.2 0.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 1.3 GO:0055070 cellular copper ion homeostasis(GO:0006878) copper ion homeostasis(GO:0055070)
0.1 1.2 GO:0015940 pantothenate metabolic process(GO:0015939) pantothenate biosynthetic process(GO:0015940)
0.1 0.8 GO:0016233 telomere capping(GO:0016233)
0.1 0.8 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.4 GO:0045727 positive regulation of translation(GO:0045727)
0.1 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.1 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 1.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.2 GO:0043549 regulation of kinase activity(GO:0043549)
0.1 0.5 GO:0045116 protein neddylation(GO:0045116)
0.1 0.4 GO:0034508 centromere complex assembly(GO:0034508) kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.1 1.5 GO:0006915 apoptotic process(GO:0006915) cell death(GO:0008219) programmed cell death(GO:0012501)
0.1 1.5 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.1 3.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 0.5 GO:0006862 nucleotide transport(GO:0006862)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0035690 cellular response to drug(GO:0035690) regulation of response to drug(GO:2001023) positive regulation of response to drug(GO:2001025) regulation of cellular response to drug(GO:2001038) positive regulation of cellular response to drug(GO:2001040)
0.1 0.1 GO:0016320 endoplasmic reticulum membrane fusion(GO:0016320)
0.1 0.5 GO:0007323 peptide pheromone maturation(GO:0007323)
0.1 0.2 GO:0006056 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506)
0.1 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) isoleucine biosynthetic process(GO:0009097)
0.1 0.8 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 0.3 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 0.2 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 0.2 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)(GO:0000388)
0.1 0.5 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.1 GO:0019348 polyprenol metabolic process(GO:0016093) polyprenol biosynthetic process(GO:0016094) dolichol metabolic process(GO:0019348) dolichol biosynthetic process(GO:0019408)
0.1 0.5 GO:0044774 mitotic DNA integrity checkpoint(GO:0044774)
0.1 0.7 GO:0048193 Golgi vesicle transport(GO:0048193)
0.1 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0035065 regulation of histone acetylation(GO:0035065) regulation of protein acetylation(GO:1901983) regulation of peptidyl-lysine acetylation(GO:2000756)
0.0 0.0 GO:0072595 maintenance of protein localization in organelle(GO:0072595)
0.0 0.0 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0015918 sterol transport(GO:0015918)
0.0 0.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.2 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.3 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:0009416 response to light stimulus(GO:0009416)
0.0 0.1 GO:0006771 riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231)
0.0 0.1 GO:0031047 gene silencing involved in chronological cell aging(GO:0010978) gene silencing by RNA(GO:0031047)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.1 GO:0007118 budding cell apical bud growth(GO:0007118)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 22.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
6.8 6.8 GO:0044427 chromosomal part(GO:0044427)
4.2 12.5 GO:0070545 PeBoW complex(GO:0070545)
4.1 12.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
3.4 16.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
2.8 232.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
2.7 8.2 GO:0030428 cell septum(GO:0030428)
2.6 10.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
2.6 15.3 GO:0043527 tRNA methyltransferase complex(GO:0043527)
2.4 9.8 GO:0017053 transcriptional repressor complex(GO:0017053)
2.4 9.6 GO:0070860 RNA polymerase I core factor complex(GO:0070860)
2.2 135.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
2.2 6.6 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
2.1 6.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
2.0 28.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
2.0 12.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
1.9 5.7 GO:0005827 polar microtubule(GO:0005827) tubulin complex(GO:0045298)
1.7 1.7 GO:0005828 kinetochore microtubule(GO:0005828)
1.7 10.1 GO:0016272 prefoldin complex(GO:0016272)
1.7 8.4 GO:0032545 CURI complex(GO:0032545)
1.6 6.6 GO:0005797 Golgi medial cisterna(GO:0005797)
1.6 6.4 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
1.6 7.8 GO:0030689 Noc complex(GO:0030689)
1.5 26.2 GO:0022626 cytosolic ribosome(GO:0022626)
1.5 1.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
1.5 6.0 GO:0044426 cell wall part(GO:0044426) external encapsulating structure part(GO:0044462)
1.5 4.5 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
1.4 10.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
1.4 5.7 GO:0042788 polysomal ribosome(GO:0042788)
1.4 4.2 GO:0070985 TFIIK complex(GO:0070985)
1.4 6.8 GO:0005663 DNA replication factor C complex(GO:0005663)
1.4 8.1 GO:0042555 MCM complex(GO:0042555)
1.3 20.2 GO:0005940 septin ring(GO:0005940)
1.3 5.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
1.3 18.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.3 6.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
1.3 3.8 GO:0097344 Rix1 complex(GO:0097344)
1.2 9.7 GO:0051233 spindle midzone(GO:0051233)
1.2 6.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.2 3.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.2 5.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.1 4.6 GO:0034990 mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990)
1.1 4.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.1 6.6 GO:0000136 alpha-1,6-mannosyltransferase complex(GO:0000136)
1.1 3.2 GO:0005845 mRNA cap binding complex(GO:0005845)
1.1 4.3 GO:0005641 nuclear envelope lumen(GO:0005641)
1.1 40.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.1 2.1 GO:0034518 RNA cap binding complex(GO:0034518)
1.0 3.1 GO:0000131 incipient cellular bud site(GO:0000131)
1.0 3.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.0 5.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
1.0 3.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.9 15.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.9 3.7 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.9 5.6 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.9 10.2 GO:0030867 rough endoplasmic reticulum(GO:0005791) rough endoplasmic reticulum membrane(GO:0030867)
0.9 2.8 GO:0000262 cytoplasmic chromosome(GO:0000229) mitochondrial chromosome(GO:0000262)
0.9 10.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.9 11.6 GO:0000786 nucleosome(GO:0000786)
0.9 6.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.9 7.0 GO:0031933 nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933)
0.8 149.3 GO:0005933 cellular bud(GO:0005933)
0.8 30.6 GO:0005811 lipid particle(GO:0005811)
0.8 3.1 GO:0000938 GARP complex(GO:0000938)
0.8 5.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.8 5.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.7 3.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.7 3.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.7 2.2 GO:0043529 GET complex(GO:0043529)
0.7 2.8 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.7 2.0 GO:0033186 CAF-1 complex(GO:0033186)
0.7 7.4 GO:0034399 nuclear periphery(GO:0034399)
0.7 2.0 GO:0008275 gamma-tubulin small complex, spindle pole body(GO:0000928) gamma-tubulin complex(GO:0000930) gamma-tubulin small complex(GO:0008275)
0.7 2.0 GO:0034456 protein kinase CK2 complex(GO:0005956) UTP-C complex(GO:0034456)
0.7 4.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.7 7.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.7 2.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.7 6.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.6 63.7 GO:0005730 nucleolus(GO:0005730)
0.6 0.6 GO:0071561 nucleus-vacuole junction(GO:0071561)
0.6 5.1 GO:0005688 U6 snRNP(GO:0005688)
0.6 34.6 GO:0030684 preribosome(GO:0030684)
0.6 1.9 GO:0000814 ESCRT II complex(GO:0000814)
0.6 2.4 GO:0097042 extrinsic component of fungal-type vacuolar membrane(GO:0097042)
0.6 2.4 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.6 1.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.6 5.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.6 2.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.6 3.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.5 3.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.5 3.2 GO:0072686 mitotic spindle(GO:0072686)
0.5 3.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.5 14.4 GO:0005840 ribosome(GO:0005840)
0.5 2.1 GO:0000818 MIS12/MIND type complex(GO:0000444) nuclear MIS12/MIND complex(GO:0000818)
0.5 2.1 GO:0033176 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) vacuolar proton-transporting V-type ATPase complex(GO:0016471) proton-transporting V-type ATPase complex(GO:0033176) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.5 2.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.5 2.1 GO:0030907 MBF transcription complex(GO:0030907)
0.5 1.0 GO:0008278 nuclear cohesin complex(GO:0000798) cohesin complex(GO:0008278)
0.5 1.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.5 3.5 GO:0000346 transcription export complex(GO:0000346)
0.5 7.5 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.5 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 1.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.5 0.5 GO:0070209 ASTRA complex(GO:0070209)
0.5 2.4 GO:0005871 kinesin complex(GO:0005871)
0.5 1.4 GO:0000113 nucleotide-excision repair factor 4 complex(GO:0000113)
0.5 0.5 GO:0005884 actin filament(GO:0005884)
0.4 4.0 GO:0000243 commitment complex(GO:0000243)
0.4 0.4 GO:0032153 cell division site(GO:0032153) cell division site part(GO:0032155)
0.4 1.7 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.4 2.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.4 4.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.4 0.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.4 1.7 GO:0000811 GINS complex(GO:0000811)
0.4 8.0 GO:0005844 polysome(GO:0005844)
0.4 3.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 3.2 GO:0030008 TRAPP complex(GO:0030008)
0.4 1.2 GO:0005796 Golgi lumen(GO:0005796)
0.4 6.2 GO:0036464 cytoplasmic mRNA processing body(GO:0000932) ribonucleoprotein granule(GO:0035770) cytoplasmic ribonucleoprotein granule(GO:0036464)
0.4 1.1 GO:0031417 NatC complex(GO:0031417)
0.4 1.1 GO:0046930 pore complex(GO:0046930)
0.4 1.1 GO:0070939 Dsl1p complex(GO:0070939)
0.4 2.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 10.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.4 1.4 GO:0030286 dynein complex(GO:0030286)
0.4 1.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 3.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 0.3 GO:0035859 Seh1-associated complex(GO:0035859)
0.3 3.5 GO:0061695 transferase complex, transferring phosphorus-containing groups(GO:0061695)
0.3 6.1 GO:0016586 RSC complex(GO:0016586)
0.3 1.0 GO:0097255 R2TP complex(GO:0097255)
0.3 0.6 GO:1990904 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.3 1.2 GO:0000815 ESCRT III complex(GO:0000815)
0.3 0.6 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.3 0.8 GO:0005823 central plaque of spindle pole body(GO:0005823)
0.3 0.8 GO:0005825 half bridge of spindle pole body(GO:0005825)
0.3 2.2 GO:0017119 Golgi transport complex(GO:0017119)
0.3 4.1 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.3 1.6 GO:0070772 PAS complex(GO:0070772)
0.3 1.0 GO:0033597 mitotic checkpoint complex(GO:0033597)
0.2 9.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.2 0.2 GO:0000133 polarisome(GO:0000133)
0.2 7.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 0.7 GO:0035649 Nrd1 complex(GO:0035649)
0.2 1.2 GO:0034044 exomer complex(GO:0034044)
0.2 0.5 GO:0032126 eisosome(GO:0032126)
0.2 6.9 GO:0005643 nuclear pore(GO:0005643)
0.2 0.9 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 0.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.7 GO:0042597 periplasmic space(GO:0042597)
0.2 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 0.2 GO:0031391 Elg1 RFC-like complex(GO:0031391)
0.2 0.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 2.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 3.7 GO:0005802 trans-Golgi network(GO:0005802)
0.2 2.1 GO:0034708 methyltransferase complex(GO:0034708)
0.2 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 0.7 GO:0070775 NuA3 histone acetyltransferase complex(GO:0033100) H3 histone acetyltransferase complex(GO:0070775)
0.2 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 0.5 GO:0000417 HIR complex(GO:0000417)
0.2 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 1.3 GO:0090544 SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544)
0.2 0.6 GO:0055087 Ski complex(GO:0055087)
0.1 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.4 GO:0097196 Shu complex(GO:0097196)
0.1 1.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 2.8 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.1 1.0 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.3 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 2.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 3.8 GO:0030479 actin cortical patch(GO:0030479) endocytic patch(GO:0061645)
0.1 1.6 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.6 GO:0031248 protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493)
0.1 1.6 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 1.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.9 GO:0071782 cortical endoplasmic reticulum(GO:0032541) endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.2 GO:0000792 heterochromatin(GO:0000792)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.3 GO:0045254 mitochondrial pyruvate dehydrogenase complex(GO:0005967) pyruvate dehydrogenase complex(GO:0045254)
0.1 0.1 GO:0000145 exocyst(GO:0000145)
0.1 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 8.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 55.7 GO:0005634 nucleus(GO:0005634)
0.1 0.6 GO:0000151 ubiquitin ligase complex(GO:0000151)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 50.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
6.9 20.8 GO:0070568 guanylyltransferase activity(GO:0070568)
6.1 18.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
5.9 23.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
5.5 22.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
5.0 19.9 GO:0016841 ammonia-lyase activity(GO:0016841)
4.8 14.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
4.7 28.0 GO:0016408 C-acyltransferase activity(GO:0016408)
4.6 18.3 GO:0015146 pentose transmembrane transporter activity(GO:0015146)
4.3 12.8 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
3.9 11.8 GO:0051219 phosphoprotein binding(GO:0051219)
3.4 10.1 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
3.0 12.2 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
3.0 9.1 GO:0001169 transcription factor activity, RNA polymerase I CORE element sequence-specific binding(GO:0001169) transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting(GO:0001187)
2.9 11.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
2.7 16.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
2.7 8.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
2.4 23.9 GO:0005216 ion channel activity(GO:0005216)
2.3 14.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
2.3 59.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
2.2 13.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
2.1 6.4 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
2.0 6.1 GO:0019003 GDP binding(GO:0019003)
2.0 8.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
2.0 28.3 GO:0001054 RNA polymerase I activity(GO:0001054)
2.0 6.0 GO:0072341 modified amino acid binding(GO:0072341)
1.8 5.4 GO:0009922 fatty acid elongase activity(GO:0009922)
1.8 9.0 GO:0004707 MAP kinase activity(GO:0004707)
1.8 7.1 GO:0004622 lysophospholipase activity(GO:0004622)
1.7 7.0 GO:0004771 sterol esterase activity(GO:0004771)
1.7 8.6 GO:0008536 Ran GTPase binding(GO:0008536)
1.7 22.0 GO:0003746 translation elongation factor activity(GO:0003746)
1.7 346.8 GO:0003735 structural constituent of ribosome(GO:0003735)
1.6 1.6 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
1.6 4.7 GO:0033592 RNA strand annealing activity(GO:0033592) annealing activity(GO:0097617)
1.6 4.7 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.6 4.7 GO:0016872 intramolecular lyase activity(GO:0016872)
1.5 4.6 GO:0004100 chitin synthase activity(GO:0004100)
1.5 4.6 GO:0019202 amino acid kinase activity(GO:0019202)
1.5 15.2 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
1.4 5.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
1.4 5.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
1.4 7.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
1.4 4.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
1.4 4.2 GO:0016504 peptidase activator activity(GO:0016504)
1.4 8.3 GO:0003993 acid phosphatase activity(GO:0003993)
1.3 8.1 GO:0015248 sterol transporter activity(GO:0015248)
1.3 6.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
1.3 7.5 GO:0008143 poly(A) binding(GO:0008143) poly-purine tract binding(GO:0070717)
1.3 41.3 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
1.3 12.5 GO:0019239 deaminase activity(GO:0019239)
1.2 2.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
1.2 5.0 GO:0009378 four-way junction helicase activity(GO:0009378)
1.2 3.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
1.2 1.2 GO:0001082 transcription factor activity, RNA polymerase I transcription factor binding(GO:0001082)
1.2 3.7 GO:0010521 telomerase inhibitor activity(GO:0010521)
1.2 4.9 GO:0001055 RNA polymerase II activity(GO:0001055)
1.2 3.7 GO:0000339 RNA cap binding(GO:0000339)
1.2 75.4 GO:0003924 GTPase activity(GO:0003924)
1.2 4.6 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
1.1 11.5 GO:0030295 protein kinase activator activity(GO:0030295)
1.1 6.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.1 6.8 GO:0019201 nucleotide kinase activity(GO:0019201)
1.1 3.4 GO:0051010 microtubule plus-end binding(GO:0051010)
1.1 7.7 GO:0030145 manganese ion binding(GO:0030145)
1.1 3.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.0 4.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
1.0 10.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
1.0 4.9 GO:0032934 steroid binding(GO:0005496) sterol binding(GO:0032934)
1.0 4.9 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
1.0 3.9 GO:0004497 monooxygenase activity(GO:0004497)
1.0 3.9 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.9 1.9 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.9 16.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.9 3.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.9 0.9 GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity(GO:0003825)
0.9 2.6 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.9 2.6 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.8 26.3 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.8 3.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.8 2.5 GO:0016972 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) thiol oxidase activity(GO:0016972)
0.8 7.4 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.8 11.3 GO:0042803 protein homodimerization activity(GO:0042803)
0.8 4.0 GO:0008312 7S RNA binding(GO:0008312)
0.8 3.1 GO:1904680 peptide transmembrane transporter activity(GO:1904680)
0.8 6.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.8 3.0 GO:0008252 nucleotidase activity(GO:0008252)
0.8 2.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.7 2.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.7 2.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.7 18.7 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.7 56.6 GO:0016791 phosphatase activity(GO:0016791)
0.7 3.5 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.7 3.5 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.7 9.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.7 3.4 GO:0042123 glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124)
0.7 2.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033) alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.7 2.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.7 3.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.7 3.4 GO:0008443 phosphofructokinase activity(GO:0008443)
0.7 8.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.7 4.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.7 2.0 GO:0030695 GTPase regulator activity(GO:0030695)
0.7 6.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.6 22.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.6 3.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.6 23.1 GO:0042393 histone binding(GO:0042393)
0.6 2.5 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
0.6 15.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.6 8.2 GO:0001671 ATPase activator activity(GO:0001671)
0.6 2.9 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.6 6.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 4.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.6 1.7 GO:0004691 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.6 3.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.6 1.7 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.5 6.5 GO:0005199 structural constituent of cell wall(GO:0005199)
0.5 1.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.5 3.7 GO:0008422 beta-glucosidase activity(GO:0008422)
0.5 3.7 GO:0031386 protein tag(GO:0031386)
0.5 7.9 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.5 2.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.5 2.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.5 4.6 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.5 2.0 GO:0005034 osmosensor activity(GO:0005034)
0.5 1.5 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.5 5.0 GO:0030276 clathrin binding(GO:0030276)
0.5 3.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.5 2.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.5 6.0 GO:0051015 actin filament binding(GO:0051015)
0.5 1.5 GO:0003680 AT DNA binding(GO:0003680)
0.5 3.9 GO:0000049 tRNA binding(GO:0000049)
0.5 1.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.5 4.2 GO:0015079 potassium ion transmembrane transporter activity(GO:0015079)
0.5 1.4 GO:0070336 flap-structured DNA binding(GO:0070336)
0.5 5.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.5 4.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 3.1 GO:0017069 snRNA binding(GO:0017069)
0.4 2.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.4 5.7 GO:0019843 rRNA binding(GO:0019843)
0.4 2.1 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.4 3.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.4 14.0 GO:0030674 protein binding, bridging(GO:0030674)
0.4 2.1 GO:0003777 microtubule motor activity(GO:0003777)
0.4 12.2 GO:0046982 protein heterodimerization activity(GO:0046982)
0.4 7.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.4 3.3 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4 3.3 GO:1901681 sulfur compound binding(GO:1901681)
0.4 1.2 GO:0008242 omega peptidase activity(GO:0008242)
0.4 5.7 GO:0030515 snoRNA binding(GO:0030515)
0.4 5.2 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.4 0.8 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.4 0.8 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.4 2.7 GO:0042054 histone-lysine N-methyltransferase activity(GO:0018024) histone methyltransferase activity(GO:0042054)
0.4 2.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.4 1.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.4 1.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4 10.0 GO:0015631 tubulin binding(GO:0015631)
0.4 3.3 GO:0019904 protein domain specific binding(GO:0019904)
0.4 14.5 GO:0005096 GTPase activator activity(GO:0005096)
0.4 0.7 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.3 2.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602) phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.3 1.4 GO:0017022 myosin binding(GO:0017022)
0.3 6.7 GO:0008092 cytoskeletal protein binding(GO:0008092)
0.3 7.0 GO:0016835 carbon-oxygen lyase activity(GO:0016835)
0.3 2.7 GO:0003774 motor activity(GO:0003774)
0.3 56.3 GO:0003723 RNA binding(GO:0003723)
0.3 3.6 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.3 3.2 GO:0043495 protein anchor(GO:0043495)
0.3 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 1.0 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.3 14.6 GO:0008565 protein transporter activity(GO:0008565)
0.3 0.6 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.3 3.8 GO:0016866 intramolecular transferase activity(GO:0016866)
0.3 1.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 1.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 2.1 GO:0008170 N-methyltransferase activity(GO:0008170)
0.3 1.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.3 3.5 GO:0003678 DNA helicase activity(GO:0003678)
0.3 0.9 GO:0019901 protein kinase binding(GO:0019901)
0.3 2.6 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.3 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 2.2 GO:0005516 calmodulin binding(GO:0005516)
0.3 1.4 GO:0034318 alcohol O-acetyltransferase activity(GO:0004026) alcohol O-acyltransferase activity(GO:0034318)
0.3 1.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3 0.8 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.3 6.0 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.2 0.5 GO:0004529 exodeoxyribonuclease activity(GO:0004529)
0.2 1.0 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.2 0.7 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.2 1.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.2 0.9 GO:0008169 C-methyltransferase activity(GO:0008169)
0.2 0.9 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 12.9 GO:0003682 chromatin binding(GO:0003682)
0.2 1.9 GO:0000182 rDNA binding(GO:0000182)
0.2 0.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 1.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.2 2.2 GO:0015616 DNA translocase activity(GO:0015616)
0.2 18.1 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.2 1.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 0.9 GO:0001139 transcription factor activity, core RNA polymerase II recruiting(GO:0001139)
0.2 0.4 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.2 0.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.2 0.3 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 0.9 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 0.9 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 2.3 GO:0050661 NADP binding(GO:0050661)
0.2 1.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 0.2 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
0.2 0.5 GO:0042736 NAD+ kinase activity(GO:0003951) NADH kinase activity(GO:0042736)
0.2 0.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 0.6 GO:0001168 transcription factor activity, RNA polymerase I upstream control element sequence-specific binding(GO:0001168)
0.1 0.9 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.4 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.2 GO:0099516 ion antiporter activity(GO:0099516)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.2 GO:0016624 pyruvate dehydrogenase activity(GO:0004738) oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.1 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 0.1 GO:0008144 drug binding(GO:0008144)
0.1 0.5 GO:0019207 kinase regulator activity(GO:0019207)
0.1 0.8 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.2 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0 0.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.0 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 1.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
1.4 4.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
1.2 4.7 PID E2F PATHWAY E2F transcription factor network
1.0 3.1 PID SHP2 PATHWAY SHP2 signaling
1.0 3.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.0 2.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.9 1.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.9 1.8 PID FGF PATHWAY FGF signaling pathway
0.9 8.1 PID ATR PATHWAY ATR signaling pathway
0.9 3.5 PID P73PATHWAY p73 transcription factor network
0.7 2.7 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.5 5.4 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.3 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.3 0.3 PID NOTCH PATHWAY Notch signaling pathway
0.2 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 0.5 PID MYC PATHWAY C-MYC pathway
0.2 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.0 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 29.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
3.0 48.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
2.4 2.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
2.4 19.1 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR
2.3 4.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.9 7.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
1.5 5.9 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
1.3 2.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.2 8.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.1 3.3 REACTOME SIGNALLING TO ERKS Genes involved in Signalling to ERKs
1.0 3.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.9 1.9 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.9 6.4 REACTOME METABOLISM OF MRNA Genes involved in Metabolism of mRNA
0.8 2.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.7 2.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.6 3.6 REACTOME TRANSLATION Genes involved in Translation
0.6 2.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.5 5.5 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
0.5 2.2 REACTOME M G1 TRANSITION Genes involved in M/G1 Transition
0.5 1.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.5 3.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.5 3.0 REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM Genes involved in Cytokine Signaling in Immune system
0.4 0.4 REACTOME METABOLISM OF RNA Genes involved in Metabolism of RNA
0.2 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 0.4 REACTOME S PHASE Genes involved in S Phase
0.2 0.2 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.2 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 0.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.6 REACTOME TRANSCRIPTION Genes involved in Transcription
0.1 0.1 REACTOME DEVELOPMENTAL BIOLOGY Genes involved in Developmental Biology
0.1 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.1 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1 0.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.1 REACTOME CELL CYCLE MITOTIC Genes involved in Cell Cycle, Mitotic
0.0 0.0 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription