Results for CAD1
Z-value: 1.61
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Transcription factors associated with CAD1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
CAD1
|
S000002831 | AP-1-like basic leucine zipper (bZIP) transcriptional activator |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YPL171C Show fit | 15.22 |
Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism |
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| YFL055W Show fit | 10.04 |
Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition |
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| YNL195C Show fit | 8.88 |
Putative protein of unknown function; shares a promoter with YNL194C; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
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| YAR050W Show fit | 8.45 |
Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p |
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| YHR139C Show fit | 8.00 |
Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall |
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| YOR382W Show fit | 7.82 |
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
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| YOR100C Show fit | 7.74 |
Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation |
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| YLR296W Show fit | 7.67 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YHL040C Show fit | 7.51 |
Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to ferrirubin, ferrirhodin, and related siderophores |
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| YCR007C Show fit | 7.39 |
Putative integral membrane protein, member of DUP240 gene family; YCR007C is not an essential gene |
Network of associatons between targets according to the STRING database.
First level regulatory network of CAD1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 16.7 | GO:0042244 | ascospore wall assembly(GO:0030476) spore wall assembly(GO:0042244) spore wall biogenesis(GO:0070590) ascospore wall biogenesis(GO:0070591) fungal-type cell wall assembly(GO:0071940) |
| 1.9 | 15.5 | GO:0015891 | siderophore transport(GO:0015891) |
| 1.8 | 10.8 | GO:0000501 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 0.4 | 10.3 | GO:0006119 | oxidative phosphorylation(GO:0006119) |
| 0.4 | 9.3 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 1.1 | 6.6 | GO:0060963 | positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0060963) |
| 0.2 | 6.5 | GO:0008219 | apoptotic process(GO:0006915) cell death(GO:0008219) programmed cell death(GO:0012501) |
| 1.0 | 5.9 | GO:0042407 | cristae formation(GO:0042407) |
| 1.8 | 5.3 | GO:0042843 | D-xylose catabolic process(GO:0042843) |
| 1.7 | 5.1 | GO:0015888 | thiamine transport(GO:0015888) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 22.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 12.0 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.6 | 8.4 | GO:0005619 | ascospore wall(GO:0005619) |
| 0.8 | 7.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.1 | 6.9 | GO:0044440 | endosome membrane(GO:0010008) endosomal part(GO:0044440) |
| 0.3 | 4.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 1.1 | 4.3 | GO:0097042 | extrinsic component of fungal-type vacuolar membrane(GO:0097042) |
| 0.7 | 4.2 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.2 | 4.2 | GO:0005628 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
| 0.5 | 3.4 | GO:0000112 | nucleotide-excision repair factor 3 complex(GO:0000112) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 15.3 | GO:0015293 | symporter activity(GO:0015293) |
| 0.7 | 12.6 | GO:0015297 | antiporter activity(GO:0015297) |
| 0.4 | 12.4 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 2.8 | 11.2 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 9.9 | GO:0000982 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) |
| 2.4 | 9.7 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
| 0.9 | 9.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.1 | 7.7 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 1.9 | 7.5 | GO:0015603 | siderophore transmembrane transporter activity(GO:0015343) iron chelate transmembrane transporter activity(GO:0015603) siderophore transporter activity(GO:0042927) |
| 0.7 | 5.4 | GO:0015205 | nucleobase transmembrane transporter activity(GO:0015205) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 124.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 1.5 | 4.5 | PID FOXO PATHWAY | FoxO family signaling |
| 0.6 | 1.9 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.4 | 1.6 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.4 | 0.7 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.3 | 0.6 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.2 | 0.5 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.4 | 0.4 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.1 | 0.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 0.4 | PID CMYB PATHWAY | C-MYB transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 124.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.3 | 2.5 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.3 | 2.4 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.4 | 1.3 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.2 | 1.2 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.1 | 0.7 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.1 | 0.6 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.2 | 0.5 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.1 | 0.4 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 0.3 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |