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Results for CAT8

Z-value: 1.24

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Transcription factors associated with CAT8

Gene Symbol Gene ID Gene Info
CAT8
S000004893 Zinc cluster transcriptional activator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CAT8YMR280C-0.911.7e-10Click!

Activity profile of CAT8 motif

Sorted Z-values of CAT8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YFR055W 38.64
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YFR056C 32.28 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YLR154W-A 28.29 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154W-B 27.22 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154C 26.63
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YNL178W 20.79
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YLR154W-C 18.95
TAR1
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
YDR098C 16.03
GRX3
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
YER131W 13.44
RPS26B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
YDR345C 11.10
HXT3
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
YOL086C 10.53
ADH1
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
YPL250W-A 10.46 Identified by fungal homology and RT-PCR
YDL047W 10.19
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YFL022C 9.73
FRS2
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YFR054C 9.24 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOR226C 8.28
ISU2
Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable
YGR251W 8.02 Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene
YHR208W 7.79
BAT1
Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase
YBL063W 7.77
KIP1
Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p
YBR158W 7.69
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YJL153C 7.61
INO1
Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
YDR344C 7.57 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGL055W 7.32
OLE1
Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
YER146W 7.08
LSM5
Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA
YFL015C 7.05 Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene
YFL015W-A 6.98 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOL124C 6.78
TRM11
Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain
YGR138C 6.76
TPO2
Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily
YMR290C 6.72
HAS1
ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles
YNR001W-A 6.72 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YMR290W-A 6.57 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YMR001C-A 6.42 Putative protein of unknown function
YNR016C 6.36
ACC1
Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids
YNL065W 6.34
AQR1
Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids
YPL075W 6.32
GCR1
Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p
YDR033W 6.18
MRH1
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p
YKL110C 6.14
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YOR272W 6.05
YTM1
Constituent of 66S pre-ribosomal particles, required for maturation of the large ribosomal subunit
YDR133C 5.80 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C
YDL023C 5.69 Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance
YAL038W 5.67
CDC19
Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
YOR376W-A 5.53 Putative protein of unknown function; identified by fungal homology and RT-PCR
YLL045C 5.45
RPL8B
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
YGR140W 5.41
CBF2
Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
YDR095C 5.38 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YKL096W-A 5.38
CWP2
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored
YGR052W 5.37
FMP48
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation
YJR094W-A 5.35
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YIL118W 5.31
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YDL022C-A 5.25 Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene DIA3; identified by fungal homology and RT-PCR
YIL009W 5.19
FAA3
Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YOR271C 5.09
FSF1
Putative protein, predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis
YDL007W 4.99
RPT2
One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle
YKR041W 4.94 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YDR094W 4.91 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2
YMR205C 4.85
PFK2
Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
YDL048C 4.84
STP4
Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p
YKR038C 4.83
KAE1
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
YMR011W 4.79
HXT2
High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose
YDL022W 4.74
GPD1
NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
YKR075C 4.71 Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YDL241W 4.61 Putative protein of unknown function; YDL241W is not an essential gene
YDR279W 4.59
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YOR375C 4.59
GDH1
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources
YOR063W 4.58
RPL3
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
YGR050C 4.56 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YKL063C 4.48 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
YER130C 4.46 Hypothetical protein
YIR021W 4.40
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YOL085C 4.35 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOL085W-A
YHR128W 4.33
FUR1
Uracil phosphoribosyltransferase, synthesizes UMP from uracil; involved in the pyrimidine salvage pathway
YGL031C 4.29
RPL24A
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YPR157W 4.26 Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation
YHR094C 4.25
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YDL085C-A 4.20 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YGR139W 4.12 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDL211C 4.12 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
YOL123W 4.09
HRP1
Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences
YNL118C 4.03
DCP2
Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family
YEL053W-A 4.02 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YEL054C
YCR031C 4.01
RPS14A
Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins
YIL009C-A 3.98
EST3
Component of the telomerase holoenzyme, involved in telomere replication
YER012W 3.96
PRE1
Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle
YHR216W 3.89
IMD2
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
YIL148W 3.86
RPL40A
Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes
YPL263C 3.84
KEL3
Cytoplasmic protein of unknown function
YMR108W 3.84
ILV2
Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control
YGL030W 3.82
RPL30
Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript
YJL158C 3.80
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
YBR106W 3.78
PHO88
Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations
YGL009C 3.74
LEU1
Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway
YNR054C 3.73
ESF2
Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome
YEL054C 3.69
RPL12A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Bp; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins
YBL077W 3.68 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene ILS1/YBL076C
YDL075W 3.64
RPL31A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YDR144C 3.63
MKC7
GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p
YGR051C 3.61 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene
YOR096W 3.53
RPS7A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins
YJL145W 3.51
SFH5
Putative phosphatidylinositol transfer protein (PITP), exhibits phosphatidylinositol- but not phosphatidylcholine-transfer activity, localized to cytosol and microsomes, similar to Sec14p; may be PITP regulator rather than actual PITP
YPR074C 3.50
TKL1
Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
YDR146C 3.48
SWI5
Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase
YLR325C 3.43
RPL38
Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein
YFR025C 3.42
HIS2
Histidinolphosphatase, catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control
YMR123W 3.41
PKR1
V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0); overproduction confers resistance to Pichia farinosa killer toxin
YLR355C 3.41
ILV5
Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA and found in mitochondrial nucleoids
YJR016C 3.40
ILV3
Dihydroxyacid dehydratase, catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids
YMR217W 3.36
GUA1
GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation
YNL289W 3.35
PCL1
Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth
YLR257W 3.34 Putative protein of unknown function
YFL016C 3.34
MDJ1
Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones
YGL097W 3.29
SRM1
Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p
YPL062W 3.27 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation
YLR328W 3.27
NMA1
Nicotinic acid mononucleotide adenylyltransferase, involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways
YMR102C 3.26 Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
YHR163W 3.26
SOL3
6-phosphogluconolactonase, catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p
YNL162W 3.26
RPL42A
Protein component of the large (60S) ribosomal subunit, identical to Rpl42Bp and has similarity to rat L44 ribosomal protein
YGR060W 3.23
ERG25
C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol
YMR183C 3.22
SSO2
Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p
YEL068C 3.21 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YKL119C 3.21
VPH2
Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER)
YDR385W 3.19
EFT2
Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
YDR044W 3.19
HEM13
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
YJR145C 3.18
RPS4A
Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
YER055C 3.16
HIS1
ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control
YKL008C 3.16
LAC1
Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p
YNL111C 3.14
CYB5
Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation
YHR181W 3.13
SVP26
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment
YOL101C 3.13
IZH4
Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism
YBR032W 3.12 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data
YGR218W 3.10
CRM1
Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus
YLR344W 3.04
RPL26A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Bp and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA
YOL038W 2.94
PRE6
Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress
YGL202W 2.93
ARO8
Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis
YPR043W 2.93
RPL43A
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Bp and has similarity to rat L37a ribosomal protein; null mutation confers a dominant lethal phenotype
YLR109W 2.93
AHP1
Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p
YDR215C 2.92 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein
YEL020C-B 2.90 Dubious open reading frame unlikely to encode a protein; partially overlaps verified gene YEL020W-A; identified by fungal homology and RT-PCR
YPR102C 2.89
RPL11A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Bp; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11
YKL218C 2.88
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YOR293W 2.85
RPS10A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Bp and has similarity to rat ribosomal protein S10
YLR312W-A 2.83
MRPL15
Mitochondrial ribosomal protein of the large subunit
YDR037W 2.80
KRS1
Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis
YGL120C 2.79
PRP43
RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript metabolism, involved in release of the lariat-intron from the spliceosome
YPL197C 2.78 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the ribosomal gene RPB7B
YER091C 2.74
MET6
Cobalamin-independent methionine synthase, involved in amino acid biosynthesis; requires a minimum of two glutamates on the methyltetrahydrofolate substrate, similar to bacterial metE homologs
YMR263W 2.72
SAP30
Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is involved in silencing at telomeres, rDNA, and silent mating-type loci; involved in telomere maintenance
YMR012W 2.70
CLU1
eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant
YJR105W 2.69
ADO1
Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle
YKL182W 2.68
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YBL085W 2.66
BOI1
Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
YKL120W 2.64
OAC1
Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and thiosulfate; member of the mitochondrial carrier family
YKL081W 2.62
TEF4
Translation elongation factor EF-1 gamma
YML127W 2.61
RSC9
Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway
YER177W 2.58
BMH1
14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling
YOR029W 2.57 Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data
YBR182C-A 2.57 Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
YLL008W 2.56
DRS1
Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles
YBR257W 2.55
POP4
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in Rnase P
YDR047W 2.53
HEM12
Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; activity inhibited by Cu2+, Zn2+, Fe2+, Fe3+ and sulfhydryl-specific reagents
YLR249W 2.53
YEF3
Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP
YNR017W 2.52
TIM23
Essential protein of the mitochondrial inner membrane, component of the mitochondrial import system
YGL209W 2.52
MIG2
Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
YEL066W 2.51
HPA3
D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro
YMR303C 2.51
ADH2
Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1
YPR029C 2.48
APL4
Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport
YOR320C 2.48
GNT1
N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus
YMR106C 2.48
YKU80
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
YGR108W 2.48
CLB1
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YPR063C 2.48 ER-localized protein of unknown function
YLR212C 2.46
TUB4
Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body
YDR101C 2.43
ARX1
Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit biogenesis; interacts directly with Alb1; responsible for Tif6 recycling defects in absence of Rei1; associated with the ribosomal export complex
YBR206W 2.42 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene KTR3
YJR047C 2.42
ANB1
Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions
YER137C 2.41 Putative protein of unknown function
YGR264C 2.40
MES1
Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs
YDR450W 2.40
RPS18A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Bp and has similarity to E. coli S13 and rat S18 ribosomal proteins
YOR273C 2.40
TPO4
Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily
YBL070C 2.39 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YCL018W 2.38
LEU2
Beta-isopropylmalate dehydrogenase (IMDH), catalyzes the third step in the leucine biosynthesis pathway
YLR132C 2.36 Protein of unknown function; green fluorescent protein (GFP)-tagged protein localizes to mitochondria and nucleus; YLR132C is an essential gene
YDL134C 2.33
PPH21
Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis
YGR265W 2.32 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MES1/YGR264C, which encodes methionyl-tRNA synthetase
YBR210W 2.32
ERV15
Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p
YOR269W 2.32
PAC1
Protein involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; synthetic lethal with bni1; homolog of human LIS1
YMR037C 2.31
MSN2
Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
YOR342C 2.30 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus
YKL009W 2.30
MRT4
Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus
YOR108W 2.30
LEU9
Alpha-isopropylmalate synthase II (2-isopropylmalate synthase), catalyzes the first step in the leucine biosynthesis pathway; the minor isozyme, responsible for the residual alpha-IPMS activity detected in a leu4 null mutant
YGR020C 2.28
VMA7
Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane
YGL158W 2.27
RCK1
Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations
YKL219W 2.24
COS9
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
YLR262C 2.24
YPT6
GTPase, Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi, maturation of the vacuolar carboxypeptidase Y; has similarity to the human GTPase, Rab6
YHR007C 2.23
ERG11
Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family
YOR028C 2.22
CIN5
Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus
YHR180W-A 2.21 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious ORF YHR180C-B and long terminal repeat YHRCsigma3
YIL133C 2.21
RPL16A
N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p
YPL090C 2.20
RPS6A
Protein component of the small (40S) ribosomal subunit; identical to Rps6Bp and has similarity to rat S6 ribosomal protein
YKR092C 2.19
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YLR108C 2.16 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene
YKL118W 2.16 Dubious open reading frame, unlikely to encode a protein; partially overlaps the verified gene VPH2

Network of associatons between targets according to the STRING database.

First level regulatory network of CAT8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.9 38.6 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
4.5 31.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
3.2 9.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
2.9 11.8 GO:0000296 spermine transport(GO:0000296)
2.9 17.4 GO:0009099 valine biosynthetic process(GO:0009099)
2.7 48.5 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
2.6 7.8 GO:0030541 plasmid partitioning(GO:0030541)
2.4 7.3 GO:0033559 unsaturated fatty acid biosynthetic process(GO:0006636) unsaturated fatty acid metabolic process(GO:0033559)
2.1 6.3 GO:0072363 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
1.9 5.6 GO:0045901 positive regulation of translational elongation(GO:0045901)
1.9 9.3 GO:0017157 regulation of exocytosis(GO:0017157) regulation of secretion(GO:0051046) regulation of secretion by cell(GO:1903530)
1.8 12.7 GO:0043457 regulation of cellular respiration(GO:0043457)
1.7 8.7 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
1.7 6.6 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
1.6 14.4 GO:0000947 amino acid catabolic process to alcohol via Ehrlich pathway(GO:0000947)
1.6 3.1 GO:0070417 response to cold(GO:0009409) cellular response to cold(GO:0070417)
1.6 1.6 GO:0035950 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
1.5 7.7 GO:0006177 GMP biosynthetic process(GO:0006177)
1.4 5.7 GO:0043097 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
1.4 6.9 GO:0009098 leucine biosynthetic process(GO:0009098)
1.4 8.2 GO:0006021 inositol biosynthetic process(GO:0006021)
1.3 3.8 GO:0043484 regulation of RNA splicing(GO:0043484) regulation of mRNA splicing, via spliceosome(GO:0048024)
1.2 4.7 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
1.0 3.0 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.0 7.0 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
1.0 2.9 GO:1902223 tyrosine biosynthetic process(GO:0006571) L-phenylalanine biosynthetic process(GO:0009094) erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process(GO:1902223)
0.9 22.3 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.9 3.5 GO:1900434 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
0.9 2.6 GO:0008272 sulfate transport(GO:0008272)
0.9 6.2 GO:0006855 drug transmembrane transport(GO:0006855)
0.8 0.8 GO:0032447 protein urmylation(GO:0032447)
0.8 0.8 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.8 4.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.8 5.7 GO:0043171 peptide catabolic process(GO:0043171)
0.8 3.3 GO:0014070 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
0.8 2.4 GO:0044209 AMP salvage(GO:0044209)
0.8 4.7 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.8 2.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.8 3.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.8 3.9 GO:0045896 regulation of transcription during mitosis(GO:0045896)
0.8 2.3 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.7 3.5 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.7 9.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.7 6.7 GO:0000105 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.7 7.4 GO:0006817 phosphate ion transport(GO:0006817)
0.7 85.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.7 2.0 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.6 11.0 GO:0030488 tRNA methylation(GO:0030488)
0.6 0.6 GO:0090342 regulation of cell aging(GO:0090342) regulation of replicative cell aging(GO:1900062)
0.6 1.9 GO:0046677 response to antibiotic(GO:0046677)
0.6 5.4 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.6 8.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.6 2.2 GO:0048313 Golgi inheritance(GO:0048313)
0.5 1.6 GO:0006673 inositolphosphoceramide metabolic process(GO:0006673)
0.5 8.2 GO:0001100 negative regulation of exit from mitosis(GO:0001100)
0.5 1.6 GO:1901976 regulation of cell cycle checkpoint(GO:1901976) negative regulation of cell cycle checkpoint(GO:1901977) regulation of DNA damage checkpoint(GO:2000001) negative regulation of DNA damage checkpoint(GO:2000002)
0.5 1.5 GO:0023021 termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.5 4.0 GO:0000372 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.5 2.5 GO:0007535 donor selection(GO:0007535)
0.5 1.9 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.5 2.4 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.5 12.7 GO:0097384 ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
0.4 2.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.4 0.4 GO:0046037 GMP metabolic process(GO:0046037)
0.4 0.9 GO:0031384 regulation of initiation of mating projection growth(GO:0031384)
0.4 2.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4 3.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.4 1.3 GO:0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674)
0.4 8.8 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.4 2.1 GO:0072668 obsolete tubulin complex biogenesis(GO:0072668)
0.4 1.6 GO:0071406 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.4 3.3 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.4 2.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4 2.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4 1.2 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.4 1.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.4 3.8 GO:0016126 steroid biosynthetic process(GO:0006694) sterol biosynthetic process(GO:0016126)
0.4 1.5 GO:0019184 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.4 2.2 GO:0006672 ceramide metabolic process(GO:0006672) ceramide biosynthetic process(GO:0046513)
0.4 4.4 GO:0006415 translational termination(GO:0006415)
0.4 2.9 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.4 2.2 GO:0006491 N-glycan processing(GO:0006491)
0.4 0.7 GO:0048211 Golgi vesicle docking(GO:0048211)
0.4 0.4 GO:0000751 mitotic cell cycle arrest in response to pheromone(GO:0000751) mitotic cell cycle arrest(GO:0071850)
0.3 0.7 GO:0015691 cadmium ion transport(GO:0015691)
0.3 3.1 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.3 2.1 GO:0030042 actin filament depolymerization(GO:0030042)
0.3 1.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.3 5.5 GO:0010833 telomere maintenance via telomerase(GO:0007004) telomere maintenance via telomere lengthening(GO:0010833)
0.3 0.7 GO:0032006 regulation of TOR signaling(GO:0032006)
0.3 2.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.3 3.0 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.3 1.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.3 14.2 GO:0055072 iron ion homeostasis(GO:0055072)
0.3 1.3 GO:0015867 ATP transport(GO:0015867)
0.3 1.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.3 1.9 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.3 0.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.3 1.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.3 7.4 GO:0006885 regulation of pH(GO:0006885)
0.3 4.0 GO:0030473 establishment of localization by movement along microtubule(GO:0010970) nuclear migration along microtubule(GO:0030473) organelle transport along microtubule(GO:0072384)
0.3 1.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 3.3 GO:0006448 regulation of translational elongation(GO:0006448)
0.3 2.7 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.3 0.3 GO:0033239 negative regulation of cellular amine metabolic process(GO:0033239)
0.3 3.8 GO:0007009 plasma membrane organization(GO:0007009)
0.3 7.2 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.3 3.4 GO:0007120 axial cellular bud site selection(GO:0007120)
0.3 1.1 GO:0034398 telomere tethering at nuclear periphery(GO:0034398)
0.3 1.1 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.3 2.7 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.3 0.8 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.2 6.6 GO:0006379 mRNA cleavage(GO:0006379)
0.2 3.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 0.7 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 5.9 GO:0009303 rRNA transcription(GO:0009303)
0.2 5.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 11.4 GO:0008033 tRNA processing(GO:0008033)
0.2 1.4 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 1.6 GO:0006771 riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231)
0.2 1.3 GO:0097502 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.2 1.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 0.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.2 1.1 GO:0015698 inorganic anion transport(GO:0015698)
0.2 2.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 2.1 GO:0019682 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.2 2.3 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.2 1.5 GO:0001402 signal transduction involved in filamentous growth(GO:0001402)
0.2 1.9 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.2 1.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.2 0.2 GO:0030811 regulation of glycolytic process(GO:0006110) regulation of nucleoside metabolic process(GO:0009118) regulation of nucleotide catabolic process(GO:0030811) regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196) regulation of ATP metabolic process(GO:1903578)
0.2 0.6 GO:0000011 vacuole inheritance(GO:0000011)
0.2 0.2 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 6.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.2 0.8 GO:0009097 isoleucine biosynthetic process(GO:0009097)
0.2 8.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 0.6 GO:0048279 vesicle fusion with endoplasmic reticulum(GO:0048279)
0.2 2.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 3.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 1.2 GO:0048017 inositol lipid-mediated signaling(GO:0048017)
0.2 0.6 GO:0000304 response to singlet oxygen(GO:0000304)
0.2 0.6 GO:0015809 arginine transport(GO:0015809)
0.2 3.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.2 0.6 GO:0045981 positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544)
0.2 2.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.2 2.3 GO:0006414 translational elongation(GO:0006414)
0.2 1.6 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.2 1.4 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.2 3.9 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.2 1.1 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.2 0.6 GO:0031167 rRNA methylation(GO:0031167)
0.2 2.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 1.4 GO:0090151 protein import into mitochondrial inner membrane(GO:0045039) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.2 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.2 0.3 GO:0042992 negative regulation of transcription factor import into nucleus(GO:0042992)
0.1 1.0 GO:0016559 peroxisome fission(GO:0016559)
0.1 2.3 GO:0016075 rRNA catabolic process(GO:0016075) ncRNA catabolic process(GO:0034661)
0.1 1.7 GO:0043094 cellular metabolic compound salvage(GO:0043094)
0.1 2.8 GO:0009266 response to temperature stimulus(GO:0009266)
0.1 0.6 GO:0015883 FAD transport(GO:0015883)
0.1 13.0 GO:0006364 rRNA processing(GO:0006364)
0.1 0.8 GO:0042991 transcription factor import into nucleus(GO:0042991)
0.1 0.4 GO:0033875 coenzyme A metabolic process(GO:0015936) nucleoside bisphosphate metabolic process(GO:0033865) ribonucleoside bisphosphate metabolic process(GO:0033875) purine nucleoside bisphosphate metabolic process(GO:0034032)
0.1 0.4 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 4.5 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.1 0.3 GO:0042710 biofilm formation(GO:0042710)
0.1 1.3 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.1 0.2 GO:0009090 homoserine biosynthetic process(GO:0009090)
0.1 0.5 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 1.3 GO:0051320 mitotic S phase(GO:0000084) S phase(GO:0051320)
0.1 1.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.2 GO:0051322 anaphase(GO:0051322)
0.1 0.5 GO:0046656 folic acid metabolic process(GO:0046655) folic acid biosynthetic process(GO:0046656)
0.1 2.6 GO:0006413 translational initiation(GO:0006413)
0.1 1.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.8 GO:0055070 cellular copper ion homeostasis(GO:0006878) copper ion homeostasis(GO:0055070)
0.1 1.0 GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion(GO:0000754) adaptation of signaling pathway(GO:0023058)
0.1 1.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.4 GO:0042435 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.1 1.5 GO:0006541 glutamine metabolic process(GO:0006541)
0.1 2.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.3 GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.1 1.7 GO:0015918 sterol transport(GO:0015918)
0.1 0.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.9 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.1 1.5 GO:0051668 localization within membrane(GO:0051668)
0.1 0.6 GO:0051278 cell wall chitin biosynthetic process(GO:0006038) fungal-type cell wall chitin biosynthetic process(GO:0034221) fungal-type cell wall polysaccharide biosynthetic process(GO:0051278) fungal-type cell wall polysaccharide metabolic process(GO:0071966)
0.1 1.0 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.6 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.1 0.2 GO:0007030 Golgi organization(GO:0007030)
0.1 0.3 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 1.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613) SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244) spliceosomal snRNP assembly(GO:0000387)
0.1 1.7 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 0.2 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1 0.2 GO:0034517 endoplasmic reticulum membrane fusion(GO:0016320) sister chromatid biorientation(GO:0031134) ribophagy(GO:0034517)
0.1 0.2 GO:1901658 nucleoside catabolic process(GO:0009164) glycosyl compound catabolic process(GO:1901658)
0.1 0.4 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.1 0.2 GO:0035434 copper ion import(GO:0015677) copper ion transmembrane transport(GO:0035434)
0.1 0.1 GO:0031684 heterotrimeric G-protein complex cycle(GO:0031684)
0.1 0.1 GO:0000087 mitotic M phase(GO:0000087) M phase(GO:0000279)
0.1 0.9 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.1 0.2 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.1 0.8 GO:0051666 actin cortical patch localization(GO:0051666)
0.1 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0031047 gene silencing involved in chronological cell aging(GO:0010978) gene silencing by RNA(GO:0031047)
0.1 0.6 GO:1901661 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.1 0.4 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889) regulation of vacuole organization(GO:0044088)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0006037 cell wall chitin metabolic process(GO:0006037) cell wall polysaccharide metabolic process(GO:0010383)
0.0 0.2 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.0 0.7 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
0.0 0.7 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.3 GO:0000147 actin cortical patch assembly(GO:0000147) actin cortical patch organization(GO:0044396)
0.0 0.1 GO:0006567 threonine catabolic process(GO:0006567)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0042176 regulation of protein catabolic process(GO:0042176)
0.0 0.0 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.0 0.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.1 GO:0019748 secondary metabolic process(GO:0019748)
0.0 0.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.1 GO:0034249 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 31.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
2.2 6.6 GO:0070545 PeBoW complex(GO:0070545)
1.8 21.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.6 4.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.4 5.4 GO:0031518 CBF3 complex(GO:0031518)
1.3 7.8 GO:0005871 kinesin complex(GO:0005871)
1.2 7.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
1.0 3.1 GO:0045298 polar microtubule(GO:0005827) tubulin complex(GO:0045298)
1.0 4.9 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.9 79.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.9 7.4 GO:0005688 U6 snRNP(GO:0005688)
0.8 2.5 GO:0008275 gamma-tubulin small complex, spindle pole body(GO:0000928) gamma-tubulin complex(GO:0000930) gamma-tubulin small complex(GO:0008275)
0.8 48.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.8 2.4 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.7 2.0 GO:0070939 Dsl1p complex(GO:0070939)
0.6 2.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.6 4.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.6 4.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.6 2.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.6 1.7 GO:0031417 NatC complex(GO:0031417)
0.6 3.9 GO:0072686 mitotic spindle(GO:0072686)
0.5 3.7 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.5 2.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.5 1.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.5 1.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.5 2.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.5 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.5 1.5 GO:0030869 RENT complex(GO:0030869)
0.5 1.9 GO:0070860 RNA polymerase I core factor complex(GO:0070860)
0.5 1.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 7.5 GO:0022626 cytosolic ribosome(GO:0022626)
0.4 3.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4 3.0 GO:0005884 actin filament(GO:0005884)
0.4 2.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.4 2.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 4.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.4 2.0 GO:0034518 RNA cap binding complex(GO:0034518)
0.4 20.3 GO:0030686 90S preribosome(GO:0030686)
0.4 0.8 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.4 1.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 2.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.4 1.1 GO:0070985 TFIIK complex(GO:0070985)
0.4 0.7 GO:0016363 nuclear matrix(GO:0016363)
0.4 1.1 GO:0071261 Ssh1 translocon complex(GO:0071261)
0.3 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.3 1.3 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.3 2.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 15.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.3 5.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 0.9 GO:0051286 cell tip(GO:0051286)
0.3 4.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.3 1.9 GO:0031933 nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933)
0.3 1.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 0.8 GO:0000417 HIR complex(GO:0000417)
0.3 2.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 3.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.2 1.0 GO:0032432 actin filament bundle(GO:0032432)
0.2 2.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 3.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 0.7 GO:0033186 CAF-1 complex(GO:0033186)
0.2 9.1 GO:0044445 cytosolic part(GO:0044445)
0.2 0.9 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 1.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 2.0 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681)
0.2 2.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2 3.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2 1.3 GO:0042555 MCM complex(GO:0042555)
0.2 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 1.6 GO:0017119 Golgi transport complex(GO:0017119)
0.2 1.7 GO:0000243 commitment complex(GO:0000243)
0.2 0.6 GO:0071561 nucleus-vacuole junction(GO:0071561)
0.2 3.3 GO:0016586 RSC complex(GO:0016586)
0.2 2.2 GO:0030118 clathrin coat(GO:0030118)
0.2 1.0 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 2.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 0.3 GO:0000786 nucleosome(GO:0000786)
0.2 2.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 0.6 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.2 0.9 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.2 0.5 GO:0042729 DASH complex(GO:0042729)
0.2 0.9 GO:0008278 nuclear cohesin complex(GO:0000798) cohesin complex(GO:0008278)
0.1 0.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 25.6 GO:0005933 cellular bud(GO:0005933)
0.1 1.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 4.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.4 GO:0000131 incipient cellular bud site(GO:0000131)
0.1 4.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 2.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 2.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.5 GO:0045254 mitochondrial pyruvate dehydrogenase complex(GO:0005967) pyruvate dehydrogenase complex(GO:0045254)
0.1 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.3 GO:0035649 Nrd1 complex(GO:0035649)
0.1 1.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.6 GO:0034044 exomer complex(GO:0034044)
0.1 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.1 0.9 GO:0090544 SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544)
0.1 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.3 GO:0000818 MIS12/MIND type complex(GO:0000444) nuclear MIS12/MIND complex(GO:0000818)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 0.3 GO:0034448 EGO complex(GO:0034448)
0.1 0.2 GO:0000837 Doa10p ubiquitin ligase complex(GO:0000837) VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.9 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.2 GO:0070823 HDA1 complex(GO:0070823)
0.1 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.4 GO:0005791 rough endoplasmic reticulum(GO:0005791) rough endoplasmic reticulum membrane(GO:0030867)
0.1 5.6 GO:0005730 nucleolus(GO:0005730)
0.1 0.2 GO:0033597 mitotic checkpoint complex(GO:0033597)
0.1 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.8 GO:0000502 proteasome complex(GO:0000502)
0.0 0.3 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.2 GO:0000817 COMA complex(GO:0000817)
0.0 0.2 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.0 0.2 GO:0031391 Elg1 RFC-like complex(GO:0031391)
0.0 3.4 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 9.0 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.1 GO:0016587 Isw1 complex(GO:0016587)
0.0 0.3 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.9 GO:0005816 microtubule organizing center(GO:0005815) spindle pole body(GO:0005816)
0.0 2.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.6 GO:0030479 actin cortical patch(GO:0030479) endocytic patch(GO:0061645)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 31.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
5.3 31.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
3.5 20.9 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
3.2 9.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
3.1 9.4 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
2.9 11.8 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
2.5 7.6 GO:0016872 intramolecular lyase activity(GO:0016872)
2.4 14.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
2.3 6.8 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
1.5 4.5 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
1.5 4.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
1.4 5.7 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
1.4 18.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.3 4.0 GO:0016504 peptidase activator activity(GO:0016504)
1.3 3.9 GO:0051219 phosphoprotein binding(GO:0051219)
1.3 6.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
1.2 4.6 GO:0015146 pentose transmembrane transporter activity(GO:0015146)
1.0 6.2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
1.0 5.1 GO:0008443 phosphofructokinase activity(GO:0008443)
1.0 5.7 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.9 3.6 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.9 2.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.9 2.6 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.8 3.3 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.8 10.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.8 4.0 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.8 3.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.8 2.3 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.8 2.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.8 5.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.8 2.3 GO:0019003 GDP binding(GO:0019003)
0.8 3.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.8 7.6 GO:0003777 microtubule motor activity(GO:0003777)
0.7 2.9 GO:0019206 nucleoside kinase activity(GO:0019206)
0.7 3.5 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.7 2.1 GO:0008097 5S rRNA binding(GO:0008097)
0.7 2.8 GO:0016854 racemase and epimerase activity(GO:0016854)
0.7 3.5 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.7 2.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.7 4.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.7 2.0 GO:0000339 RNA cap binding(GO:0000339)
0.7 2.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.6 3.8 GO:0016408 C-acyltransferase activity(GO:0016408)
0.6 117.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.6 5.5 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.5 4.4 GO:0031072 heat shock protein binding(GO:0031072)
0.5 6.3 GO:0005199 structural constituent of cell wall(GO:0005199)
0.5 2.5 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.5 1.5 GO:0004691 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.5 14.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.5 6.9 GO:0008483 transaminase activity(GO:0008483) transferase activity, transferring nitrogenous groups(GO:0016769)
0.5 4.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.5 14.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.5 1.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.5 5.6 GO:0030276 clathrin binding(GO:0030276)
0.5 1.8 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.5 1.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.4 3.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.4 7.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.4 1.9 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.4 3.1 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.4 1.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 3.8 GO:0005516 calmodulin binding(GO:0005516)
0.4 1.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 3.7 GO:0001671 ATPase activator activity(GO:0001671)
0.4 4.8 GO:0042803 protein homodimerization activity(GO:0042803)
0.4 5.1 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.4 1.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3 1.0 GO:0016972 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) thiol oxidase activity(GO:0016972)
0.3 4.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 3.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 1.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.3 3.1 GO:0005216 ion channel activity(GO:0005216)
0.3 3.7 GO:0019843 rRNA binding(GO:0019843)
0.3 1.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.3 3.2 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.3 0.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.3 3.1 GO:0051015 actin filament binding(GO:0051015)
0.3 1.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 8.4 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.3 6.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 4.4 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.3 2.3 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.2 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 1.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 1.8 GO:0032934 steroid binding(GO:0005496) sterol binding(GO:0032934)
0.2 1.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 8.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 3.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.2 0.6 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.2 3.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 1.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 1.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 2.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.2 2.2 GO:0000049 tRNA binding(GO:0000049)
0.2 1.0 GO:0008312 7S RNA binding(GO:0008312)
0.2 0.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 0.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 4.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 0.8 GO:0019201 nucleotide kinase activity(GO:0019201)
0.2 1.3 GO:0015266 protein channel activity(GO:0015266)
0.2 1.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 5.9 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.7 GO:0005354 galactose transmembrane transporter activity(GO:0005354)
0.1 1.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.6 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.4 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 2.4 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.8 GO:0042124 glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124)
0.1 1.3 GO:0010181 FMN binding(GO:0010181)
0.1 0.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 4.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 6.7 GO:0003924 GTPase activity(GO:0003924)
0.1 1.1 GO:0019239 deaminase activity(GO:0019239)
0.1 4.0 GO:0042393 histone binding(GO:0042393)
0.1 1.5 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.9 GO:0015079 potassium ion transmembrane transporter activity(GO:0015079)
0.1 0.3 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.1 1.5 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 3.4 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 0.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.8 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 1.0 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.2 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.1 1.0 GO:0051087 chaperone binding(GO:0051087)
0.1 1.3 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.1 0.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.2 GO:0019202 amino acid kinase activity(GO:0019202)
0.1 0.7 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.4 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) cyclohydrolase activity(GO:0019238)
0.1 0.1 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.1 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.7 GO:0005048 signal sequence binding(GO:0005048)
0.1 0.3 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0019904 protein domain specific binding(GO:0019904)
0.0 1.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 1.2 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.4 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.2 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.6 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.8 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 2.3 GO:0003723 RNA binding(GO:0003723)
0.0 0.0 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.0 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 PID SHP2 PATHWAY SHP2 signaling
0.6 1.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.6 0.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.4 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.4 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.3 1.2 PID E2F PATHWAY E2F transcription factor network
0.3 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 1.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 0.5 PID MYC PATHWAY C-MYC pathway
0.1 0.6 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 0.7 PID ATR PATHWAY ATR signaling pathway
0.1 0.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 0.2 PID FGF PATHWAY FGF signaling pathway
0.1 0.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 0.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 REACTOME SIGNALLING TO ERKS Genes involved in Signalling to ERKs
3.1 24.5 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
2.1 4.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.2 4.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
1.1 18.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
1.0 7.2 REACTOME METABOLISM OF MRNA Genes involved in Metabolism of mRNA
0.6 1.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.5 1.5 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.4 2.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 1.7 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR
0.2 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 1.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.3 REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION Genes involved in Platelet activation, signaling and aggregation
0.1 0.2 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1 1.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.4 REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION Genes involved in Post-translational protein modification
0.1 0.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 0.2 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.1 REACTOME TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 18.4 REACTOME GLYCOSAMINOGLYCAN METABOLISM Genes involved in Glycosaminoglycan metabolism