Gene Symbol | Gene ID | Gene Info |
---|---|---|
HAP5
|
S000005885 | Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
YDR536W | 17.20 |
STL1
|
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock |
|
YKL148C | 16.45 |
SDH1
|
Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone |
|
YAL062W | 14.36 |
GDH3
|
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources |
|
YML089C | 13.94 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage |
||
YEL008W | 12.54 |
Hypothetical protein predicted to be involved in metabolism |
||
YEL009C | 11.60 |
GCN4
|
Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels |
|
YDL204W | 11.00 |
RTN2
|
Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily |
|
YBL015W | 9.88 |
ACH1
|
Acetyl-coA hydrolase, primarily localized to mitochondria; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth |
|
YOR343C | 9.46 |
Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data |
||
YPR036W-A | 9.20 |
Protein of unknown function; transcription is regulated by Pdr1p |
||
YJR078W | 8.94 |
BNA2
|
Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p and Aft2p |
|
YML090W | 8.56 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YML089C; exhibits growth defect on a non-fermentable (respiratory) carbon source |
||
YOR378W | 8.24 |
Putative protein of unknown function; belongs to the DHA2 family of drug:H+ antiporters; YOR378W is not an essential gene |
||
YDR231C | 8.00 |
COX20
|
Mitochondrial inner membrane protein, required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase |
|
YOL047C | 7.95 |
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern |
||
YER065C | 7.65 |
ICL1
|
Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose |
|
YAR053W | 7.60 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YKL141W | 7.53 |
SDH3
|
Cytochrome b subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone |
|
YBR117C | 7.50 |
TKL2
|
Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids |
|
YKL146W | 7.47 |
AVT3
|
Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters |
|
YKL147C | 7.33 |
Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene AVT3 |
||
YGL062W | 7.10 |
PYC1
|
Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis |
|
YBL030C | 7.10 |
PET9
|
Major ADP/ATP carrier of the mitochondrial inner membrane, exchanges cytosolic ADP for mitochondrially synthesized ATP; phosphorylated; required for viability in many common lab strains carrying a mutation in the polymorphic SAL1 gene |
|
YLR122C | 6.80 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR123C |
||
YDL181W | 6.76 |
INH1
|
Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase; inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p; has similarity to Stf1p; has a calmodulin-binding motif and binds calmodulin in vitro |
|
YER158C | 6.70 |
Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p |
||
YMR256C | 6.59 |
COX7
|
Subunit VII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain |
|
YMR107W | 6.50 |
SPG4
|
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
|
YDR232W | 6.36 |
HEM1
|
5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p |
|
YCR005C | 6.24 |
CIT2
|
Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle; expression is controlled by Rtg1p and Rtg2p transcription factors |
|
YBR230C | 6.10 |
OM14
|
Integral mitochondrial outer membrane protein; abundance is decreased in cells grown in glucose relative to other carbon sources; appears to contain 3 alpha-helical transmembrane segments; ORF encodes a 97-basepair intron |
|
YDL067C | 6.09 |
COX9
|
Subunit VIIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain |
|
YGL191W | 6.06 |
COX13
|
Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP |
|
YML091C | 6.06 |
RPM2
|
Protein subunit of mitochondrial RNase P, has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus |
|
YFR053C | 5.95 |
HXK1
|
Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p |
|
YKL085W | 5.84 |
MDH1
|
Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated |
|
YAR060C | 5.81 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YGL187C | 5.71 |
COX4
|
Subunit IV of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; N-terminal 25 residues of precursor are cleaved during mitochondrial import; phosphorylated |
|
YLR123C | 5.54 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR122C; contains characteristic aminoacyl-tRNA motif |
||
YLR004C | 5.47 |
THI73
|
Putative plasma membrane permease proposed to be involved in carboxylic acid uptake and repressed by thiamine; substrate of Dbf2p/Mob1p kinase; transcription is altered if mitochondrial dysfunction occurs |
|
YER033C | 5.38 |
ZRG8
|
Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; GFP-fusion protein is localized to the cytoplasm; transcription induced under conditions of zinc deficiency |
|
YJR077C | 5.23 |
MIR1
|
Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2p under normal conditions; phosphorylated |
|
YBR039W | 5.13 |
ATP3
|
Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis |
|
YJL166W | 5.07 |
QCR8
|
Subunit 8 of ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p |
|
YNL052W | 5.05 |
COX5A
|
Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth |
|
YPL201C | 4.93 |
YIG1
|
Protein that interacts with glycerol 3-phosphatase and plays a role in anaerobic glycerol production; localizes to the nucleus and cytosol |
|
YNR002C | 4.75 |
ATO2
|
Putative transmembrane protein involved in export of ammonia, a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Ady2p and Y. lipolytica Gpr1p |
|
YBL099W | 4.73 |
ATP1
|
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated |
|
YJL116C | 4.72 |
NCA3
|
Protein that functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase; member of the SUN family |
|
YLL041C | 4.69 |
SDH2
|
Iron-sulfur protein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone |
|
YBL100C | 4.68 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the 5' end of ATP1 |
||
YDR529C | 4.62 |
QCR7
|
Subunit 7 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the mitochondrial matrix; N-terminus appears to play a role in complex assembly |
|
YJL103C | 4.61 |
GSM1
|
Putative zinc cluster protein of unknown function; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis |
|
YCL001W-B | 4.52 |
Putative protein of unknown function; identified by homology |
||
YPL078C | 4.51 |
ATP4
|
Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated |
|
YCL057C-A | 4.50 |
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
||
YHL040C | 4.49 |
ARN1
|
Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to ferrirubin, ferrirhodin, and related siderophores |
|
YIL055C | 4.43 |
Putative protein of unknown function |
||
YDR342C | 4.38 |
HXT7
|
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels |
|
YBR105C | 4.22 |
VID24
|
Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; involved in proteasome-dependent catabolite degradation of FBPase |
|
YOL084W | 4.18 |
PHM7
|
Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole |
|
YGL248W | 4.16 |
PDE1
|
Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation |
|
YGR183C | 4.14 |
QCR9
|
Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex |
|
YKL016C | 4.14 |
ATP7
|
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis |
|
YPR015C | 4.04 |
Putative protein of unknown function |
||
YDR322C-A | 3.96 |
TIM11
|
Subunit e of mitochondrial F1F0-ATPase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; essential for the dimeric and oligomeric state of ATP synthase |
|
YIL059C | 3.95 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YIL060W |
||
YHR199C | 3.92 |
AIM46
|
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss (petite formation) |
|
YDR277C | 3.87 |
MTH1
|
Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation |
|
YPL262W | 3.77 |
FUM1
|
Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation; phosphorylated in mitochondria |
|
YDR377W | 3.74 |
ATP17
|
Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis |
|
YLR023C | 3.72 |
IZH3
|
Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity |
|
YHR145C | 3.70 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YAL063C | 3.67 |
FLO9
|
Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation |
|
YEL065W | 3.66 |
SIT1
|
Ferrioxamine B transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; transcription is induced during iron deprivation and diauxic shift; potentially phosphorylated by Cdc28p |
|
YHR211W | 3.66 |
FLO5
|
Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p |
|
YLR125W | 3.58 |
Putative protein of unknown function; mutant has decreased Ty3 transposition; YLR125W is not an essential gene |
||
YML081C-A | 3.55 |
ATP18
|
Subunit of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms |
|
YPL200W | 3.54 |
CSM4
|
Protein required for accurate chromosome segregation during meiosis |
|
YOL077W-A | 3.51 |
ATP19
|
Subunit k of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase |
|
YPR010C-A | 3.50 |
Putative protein of unknown function; conserved among Saccharomyces sensu stricto species |
||
YOR186C-A | 3.47 |
Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching |
||
YLR124W | 3.45 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YEL007W | 3.45 |
Putative protein with sequence similarity to S. pombe gti1+ (gluconate transport inducer 1) |
||
YNL074C | 3.44 |
MLF3
|
Serine-rich protein of unknown function; overproduction suppresses the growth inhibition caused by exposure to the immunosuppressant leflunomide |
|
YIL162W | 3.44 |
SUC2
|
Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively |
|
YMR118C | 3.42 |
Protein of unknown function with similarity to succinate dehydrogenase cytochrome b subunit; YMR118C is not an essential gene |
||
YMR271C | 3.39 |
URA10
|
Minor orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; major OPRTase encoded by URA5 |
|
YDL170W | 3.36 |
UGA3
|
Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus |
|
YPL111W | 3.31 |
CAR1
|
Arginase, responsible for arginine degradation, expression responds to both induction by arginine and nitrogen catabolite repression; disruption enhances freeze tolerance |
|
YGR121C | 3.30 |
MEP1
|
Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation |
|
YPL135W | 3.29 |
ISU1
|
Conserved protein of the mitochondrial matrix, performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable |
|
YHR212C | 3.26 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YOR192C | 3.24 |
THI72
|
Transporter of thiamine or related compound; shares sequence similarity with Thi7p |
|
YDR476C | 3.22 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR476C is not an essential gene |
||
YGL219C | 3.22 |
MDM34
|
Mitochondrial outer membrane protein, required for normal mitochondrial morphology and inheritance; localizes to dots on the mitochondrial surface near mtDNA nucleoids; interacts genetically with MDM31 and MDM32 |
|
YJL102W | 3.18 |
MEF2
|
Mitochondrial elongation factor involved in translational elongation |
|
YOR382W | 3.12 |
FIT2
|
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
|
YLR236C | 3.11 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YNL333W | 3.09 |
SNZ2
|
Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p |
|
YHR139C | 3.04 |
SPS100
|
Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall |
|
YDR247W | 3.03 |
VHS1
|
Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p |
|
YLR174W | 3.02 |
IDP2
|
Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose |
|
YFR033C | 2.95 |
QCR6
|
Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1 |
|
YLL056C | 2.94 |
Putative protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in pleiotropic drug resistance (PDR) phenomenon; YLL056C is not an essential gene |
||
YML120C | 2.92 |
NDI1
|
NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in the respiratory chain but does not pump protons, in contrast to the higher eukaryotic multisubunit respiratory complex I; phosphorylated; homolog of human AMID |
|
YLR237W | 2.90 |
THI7
|
Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia |
|
YFL019C | 2.89 |
Dubious open reading frame unlikely to encode a protein; YFL019C is not an essential gene |
||
YLL055W | 2.89 |
YCT1
|
High-affinity cysteine-specific transporter with similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene |
|
YLR235C | 2.85 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TOP3 |
||
YPL183W-A | 2.84 |
RTC6
|
Homolog of the prokaryotic ribosomal protein L36, likely to be a mitochondrial ribosomal protein coded in the nuclear genome; null mutation suppresses cdc13-1 temperature sensitivity |
|
YPR151C | 2.82 |
SUE1
|
Mitochondrial protein required for degradation of unstable forms of cytochrome c |
|
YAL039C | 2.80 |
CYC3
|
Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS) |
|
YNL242W | 2.79 |
ATG2
|
Peripheral membrane protein required for vesicle formation during autophagy, pexophagy, and the cytoplasm-to-vaucole targeting (Cvt) pathway; involved in Atg9p cycling between the pre-autophagosomal structure and mitochondria |
|
YBR147W | 2.77 |
RTC2
|
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays fluconazole resistance and suppresses cdc13-1 temperature sensitivity |
|
YBR218C | 2.74 |
PYC2
|
Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis |
|
YOR192C-C | 2.74 |
Putative protein of unknown function; identified by expression profiling and mass spectrometry |
||
YPL230W | 2.70 |
USV1
|
Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis |
|
YOR072W | 2.68 |
Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOR072W-A; diploid deletion strains are methotrexate, paraquat and wortmannin sensitive |
||
YHR212W-A | 2.68 |
Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching |
||
YHR008C | 2.68 |
SOD2
|
Mitochondrial superoxide dismutase, protects cells against oxygen toxicity; phosphorylated |
|
YNL101W | 2.66 |
AVT4
|
Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters |
|
YER053C | 2.66 |
PIC2
|
Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Mir1p but less abundant than Mir1p under normal conditions; expression is induced at high temperature |
|
YGR149W | 2.65 |
Putative protein of unknown function; predicted to be an integal membrane protein |
||
YBL045C | 2.62 |
COR1
|
Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain |
|
YNR034W-A | 2.58 |
Putative protein of unknown function; expression is regulated by Msn2p/Msn4p |
||
YER101C | 2.55 |
AST2
|
Protein that may have a role in targeting of plasma membrane [H+]ATPase (Pma1p) to the plasma membrane, as suggested by analysis of genetic interactions |
|
YDR173C | 2.54 |
ARG82
|
Inositol polyphosphate multikinase (IPMK), sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes |
|
YJR154W | 2.52 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm |
||
YBR230W-A | 2.50 |
Putative protein of unknown function |
||
YJL043W | 2.42 |
Putative protein of unknown function; YJL043W is a non-essential gene |
||
YOL081W | 2.41 |
IRA2
|
GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin |
|
YOR376W | 2.40 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YOR376W is not an essential gene. |
||
YNL088W | 2.40 |
TOP2
|
Essential type II topoisomerase, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis |
|
YGR236C | 2.39 |
SPG1
|
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
|
YHR092C | 2.39 |
HXT4
|
High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose |
|
YAR023C | 2.37 |
Putative integral membrane protein, member of DUP240 gene family |
||
YOR071C | 2.36 |
NRT1
|
High-affinity nicotinamide riboside transporter; also transports thiamine with low affinity; shares sequence similarity with Thi7p and Thi72p; proposed to be involved in 5-fluorocytosine sensitivity |
|
YER066W | 2.32 |
Putative protein of unknown function; YER066W is not an essential gene |
||
YOR072W-A | 2.28 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR072W; originally identified by fungal homology and RT-PCR |
||
YOR100C | 2.28 |
CRC1
|
Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation |
|
YNL334C | 2.27 |
SNO2
|
Protein of unknown function, nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin |
|
YDR405W | 2.24 |
MRP20
|
Mitochondrial ribosomal protein of the large subunit |
|
YKL151C | 2.22 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm |
||
YPL240C | 2.21 |
HSP82
|
Hsp90 chaperone required for pheromone signaling and negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding and nucleotide addition; interacts with Cns1p, Cpr6p, Cpr7p, Sti1p |
|
YDR298C | 2.17 |
ATP5
|
Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase, which is an evolutionarily conserved enzyme complex required for ATP synthesis; homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein); phosphorylated |
|
YBR209W | 2.16 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR209W is not an essential gene |
||
YPL181W | 2.16 |
CTI6
|
Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain |
|
YJL100W | 2.14 |
LSB6
|
Type II phosphatidylinositol 4-kinase that binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization |
|
YNL190W | 2.11 |
Cell wall protein of unknown function; proposed role as a hydrophilin induced by osmotic stress; contains a putative GPI-attachment site |
||
YKL163W | 1.99 |
PIR3
|
O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway |
|
YFL044C | 1.98 |
OTU1
|
Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p; may contribute to regulation of protein degradation by deubiquitylating substrates that have been ubiquitylated by Ufd2p; member of the Ovarian Tumor (OTU) family |
|
YPL182C | 1.98 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CTI6/YPL181W |
||
YDL214C | 1.97 |
PRR2
|
Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor |
|
YHR048W | 1.96 |
YHK8
|
Presumed antiporter of the DHA1 family of multidrug resistance transporters; contains 12 predicted transmembrane spans; expression of gene is up-regulated in cells exhibiting reduced susceptibility to azoles |
|
YFR007W | 1.93 |
YFH7
|
Putative kinase with similarity to the phosphoribulokinase/uridine kinase/bacterial pantothenate kinase (PRK/URK/PANK) subfamily of P-loop kinases; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) |
|
YKR102W | 1.92 |
FLO10
|
Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation |
|
YER175C | 1.92 |
TMT1
|
Trans-aconitate methyltransferase, cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle |
|
YOR228C | 1.92 |
Protein of unknown function, localized to the mitochondrial outer membrane |
||
YMR145C | 1.90 |
NDE1
|
Mitochondrial external NADH dehydrogenase, a type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain |
|
YLR228C | 1.88 |
ECM22
|
Sterol regulatory element binding protein, regulates transcription of the sterol biosynthetic genes ERG2 and ERG3; member of the fungus-specific Zn[2]-Cys[6] binuclear cluster family of transcription factors; homologous to Upc2p |
|
YHR051W | 1.88 |
COX6
|
Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; expression is regulated by oxygen levels |
|
YLR395C | 1.87 |
COX8
|
Subunit VIII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain |
|
YDR148C | 1.87 |
KGD2
|
Dihydrolipoyl transsuccinylase, component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated |
|
YFL020C | 1.85 |
PAU5
|
Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme |
|
YHL046W-A | 1.84 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YOL154W | 1.83 |
ZPS1
|
Putative GPI-anchored protein; transcription is induced under low-zinc conditions, as mediated by the Zap1p transcription factor, and at alkaline pH |
|
YOL085W-A | 1.82 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YOL085C |
||
YLR307C-A | 1.82 |
Putative protein of unknown function |
||
YMR306W | 1.81 |
FKS3
|
Protein involved in spore wall assembly, has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
|
YMR148W | 1.78 |
Putative protein of unknown function; predicted to contain a transmembrane domain; YMR148W is not an essential gene |
||
YFR017C | 1.77 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YFR017C is not an essential gene |
||
YKL067W | 1.76 |
YNK1
|
Nucleoside diphosphate kinase, catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate |
|
YDR223W | 1.74 |
CRF1
|
Transcriptional corepressor involved in the regulation of ribosomal protein gene transcription via the TOR signaling pathway and protein kinase A, phosphorylated by activated Yak1p which promotes accumulation of Crf1p in the nucleus |
|
YHL047C | 1.72 |
ARN2
|
Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to the siderophore triacetylfusarinine C |
|
YBL066C | 1.72 |
SEF1
|
Putative transcription factor, has homolog in Kluyveromyces lactis |
|
YKR062W | 1.71 |
TFA2
|
TFIIE small subunit, involved in RNA polymerase II transcription initiation |
|
YKL107W | 1.69 |
Putative protein of unknown function |
||
YPR084W | 1.66 |
Putative protein of unknown function |
||
YPL187W | 1.65 |
MF(ALPHA)1
|
Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor |
|
YPL224C | 1.65 |
MMT2
|
Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt1p |
|
YLR375W | 1.65 |
STP3
|
Zinc-finger protein of unknown function, possibly involved in pre-tRNA splicing and in uptake of branched-chain amino acids |
|
YMR103C | 1.64 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YJL045W | 1.63 |
Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner |
||
YKL197C | 1.61 |
PEX1
|
AAA-peroxin that heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis |
|
YDR453C | 1.59 |
TSA2
|
Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants |
|
YOL053W | 1.59 |
AIM39
|
Putative protein of unknown function; YOL053W is not an essential gene; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) |
|
YJR151C | 1.58 |
DAN4
|
Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth |
|
YLR374C | 1.57 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF STP3/YLR375W |
||
YBL065W | 1.56 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF SEF1/YBL066C; YBL065W is a non-essential gene |
||
YPL278C | 1.56 |
Putative protein of unknown function; gene expression regulated by copper levels |
||
YLR378C | 1.56 |
SEC61
|
Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER |
|
YCL040W | 1.54 |
GLK1
|
Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources |
|
YMR018W | 1.54 |
Putative protein of unknown function with similarity to human PEX5Rp (peroxin protein 5 related protein); transcription increases during colony development similar to genes involved in peroxisome biogenesis; YMR018W is not an essential gene |
||
YFR045W | 1.51 |
Putative mitochondrial transport protein; null mutant is viable, exhibits decreased levels of chitin and normal resistance to calcofluor white |
||
YLR327C | 1.50 |
TMA10
|
Protein of unknown function that associates with ribosomes |
|
YPR193C | 1.49 |
HPA2
|
Tetrameric histone acetyltransferase with similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p; acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity |
|
YML087C | 1.49 |
AIM33
|
Putative protein of unknown function; highly conserved across species and orthologous to human CYB5R4; null mutant shows increased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media |
|
YNL240C | 1.47 |
NAR1
|
Nuclear architecture related protein; component of the cytosolic iron-sulfur (FeS) protein assembly machinery, required for maturation of cytosolic and nuclear FeS proteins; homologous to human Narf |
|
YHR210C | 1.47 |
Putative protein of unknown function; non-essential gene; highly expressed under anaeorbic conditions; sequence similarity to aldose 1-epimerases such as GAL10 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.7 | 28.7 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
3.3 | 13.3 | GO:0010688 | negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0010688) |
3.1 | 15.7 | GO:0015793 | glycerol transport(GO:0015793) |
3.0 | 27.2 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
2.9 | 8.7 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
2.8 | 8.5 | GO:0015888 | thiamine transport(GO:0015888) |
2.8 | 8.5 | GO:0035786 | protein complex oligomerization(GO:0035786) |
2.6 | 28.5 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
2.6 | 12.9 | GO:0034486 | amino acid transmembrane export from vacuole(GO:0032974) vacuolar transmembrane transport(GO:0034486) vacuolar amino acid transmembrane transport(GO:0034487) amino acid transmembrane export(GO:0044746) |
2.3 | 9.2 | GO:0045980 | negative regulation of nucleotide metabolic process(GO:0045980) |
2.2 | 24.3 | GO:0006119 | oxidative phosphorylation(GO:0006119) |
2.2 | 11.0 | GO:0043954 | cellular component maintenance(GO:0043954) |
2.2 | 8.6 | GO:0046323 | glucose import(GO:0046323) |
2.0 | 18.1 | GO:0006097 | glyoxylate cycle(GO:0006097) |
2.0 | 9.9 | GO:0034627 | 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627) |
1.9 | 5.8 | GO:0006108 | malate metabolic process(GO:0006108) |
1.9 | 7.5 | GO:0015886 | heme transport(GO:0015886) |
1.6 | 11.4 | GO:0006083 | acetate metabolic process(GO:0006083) |
1.4 | 8.6 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
1.4 | 4.2 | GO:0051469 | vesicle fusion with vacuole(GO:0051469) |
1.4 | 4.2 | GO:0046058 | cAMP metabolic process(GO:0046058) |
1.3 | 10.2 | GO:0015891 | siderophore transport(GO:0015891) |
1.2 | 3.7 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
1.2 | 3.6 | GO:0019627 | urea metabolic process(GO:0019627) |
1.1 | 4.3 | GO:0009448 | gamma-aminobutyric acid metabolic process(GO:0009448) gamma-aminobutyric acid catabolic process(GO:0009450) |
1.0 | 3.9 | GO:0045141 | meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) |
0.9 | 2.8 | GO:0017003 | protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063) |
0.9 | 2.7 | GO:0072353 | cellular age-dependent response to reactive oxygen species(GO:0072353) |
0.9 | 6.9 | GO:0042816 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819) |
0.9 | 2.6 | GO:0000101 | sulfur amino acid transport(GO:0000101) |
0.8 | 2.4 | GO:0031055 | chromatin remodeling at centromere(GO:0031055) |
0.8 | 3.0 | GO:2000911 | positive regulation of lipid transport(GO:0032370) regulation of sterol transport(GO:0032371) positive regulation of sterol transport(GO:0032373) positive regulation of transmembrane transport(GO:0034764) regulation of sterol import by regulation of transcription from RNA polymerase II promoter(GO:0035968) positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter(GO:0035969) regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) regulation of sterol import(GO:2000909) positive regulation of sterol import(GO:2000911) |
0.7 | 1.5 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
0.7 | 2.9 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
0.7 | 9.5 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
0.7 | 2.1 | GO:0045950 | negative regulation of mitotic recombination(GO:0045950) |
0.7 | 0.7 | GO:0006538 | glutamate catabolic process(GO:0006538) |
0.6 | 4.5 | GO:0015758 | glucose transport(GO:0015758) |
0.6 | 2.5 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
0.6 | 2.4 | GO:0006075 | (1->3)-beta-D-glucan biosynthetic process(GO:0006075) |
0.6 | 1.8 | GO:0046039 | GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039) |
0.6 | 3.4 | GO:0044205 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) 'de novo' UMP biosynthetic process(GO:0044205) |
0.5 | 2.0 | GO:0031138 | negative regulation of conjugation(GO:0031135) negative regulation of conjugation with cellular fusion(GO:0031138) negative regulation of multi-organism process(GO:0043901) |
0.5 | 3.5 | GO:0006101 | tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101) |
0.5 | 3.9 | GO:0005985 | sucrose metabolic process(GO:0005985) sucrose catabolic process(GO:0005987) |
0.5 | 0.9 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
0.5 | 1.8 | GO:0000949 | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway(GO:0000949) |
0.4 | 1.8 | GO:0009229 | thiamine diphosphate biosynthetic process(GO:0009229) thiamine diphosphate metabolic process(GO:0042357) |
0.4 | 0.4 | GO:0006740 | NADPH regeneration(GO:0006740) |
0.4 | 0.4 | GO:0034225 | cellular response to zinc ion starvation(GO:0034224) regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation(GO:0034225) |
0.4 | 1.2 | GO:0070199 | establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) |
0.4 | 1.6 | GO:0015976 | carbon utilization(GO:0015976) |
0.4 | 10.3 | GO:0006094 | gluconeogenesis(GO:0006094) |
0.4 | 1.6 | GO:1903513 | retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513) |
0.4 | 5.0 | GO:0019682 | pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) |
0.4 | 1.1 | GO:0005993 | trehalose catabolic process(GO:0005993) |
0.4 | 2.2 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
0.4 | 0.4 | GO:0043902 | positive regulation of multi-organism process(GO:0043902) |
0.4 | 4.7 | GO:0015749 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
0.4 | 1.1 | GO:0015847 | putrescine transport(GO:0015847) |
0.3 | 4.4 | GO:0000436 | carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) |
0.3 | 1.6 | GO:0043112 | receptor recycling(GO:0001881) protein import into peroxisome matrix, receptor recycling(GO:0016562) receptor metabolic process(GO:0043112) |
0.3 | 0.9 | GO:0042743 | hydrogen peroxide metabolic process(GO:0042743) hydrogen peroxide catabolic process(GO:0042744) |
0.3 | 0.9 | GO:0042407 | cristae formation(GO:0042407) |
0.3 | 0.9 | GO:0042843 | D-xylose catabolic process(GO:0042843) |
0.3 | 9.9 | GO:0009060 | aerobic respiration(GO:0009060) |
0.3 | 3.3 | GO:0015893 | drug transport(GO:0015893) |
0.3 | 0.9 | GO:0001111 | promoter clearance during DNA-templated transcription(GO:0001109) promoter clearance from RNA polymerase II promoter(GO:0001111) |
0.3 | 1.2 | GO:0046688 | response to copper ion(GO:0046688) |
0.3 | 1.2 | GO:0043388 | positive regulation of DNA binding(GO:0043388) regulation of DNA binding(GO:0051101) |
0.3 | 1.4 | GO:0033683 | nucleotide-excision repair, DNA incision(GO:0033683) |
0.3 | 0.6 | GO:0006343 | establishment of chromatin silencing(GO:0006343) |
0.3 | 2.2 | GO:0061188 | negative regulation of chromatin silencing at rDNA(GO:0061188) |
0.3 | 1.1 | GO:0032048 | cardiolipin metabolic process(GO:0032048) |
0.3 | 0.3 | GO:0097035 | lipid translocation(GO:0034204) regulation of membrane lipid distribution(GO:0097035) |
0.3 | 2.3 | GO:0006882 | cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069) |
0.3 | 0.5 | GO:0051228 | mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230) |
0.2 | 1.5 | GO:0051260 | protein homooligomerization(GO:0051260) |
0.2 | 1.1 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) |
0.2 | 0.9 | GO:0019184 | glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184) |
0.2 | 0.9 | GO:0019405 | alditol catabolic process(GO:0019405) glycerol catabolic process(GO:0019563) |
0.2 | 2.1 | GO:0015802 | basic amino acid transport(GO:0015802) |
0.2 | 4.8 | GO:0000422 | mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726) |
0.2 | 2.9 | GO:0019740 | nitrogen utilization(GO:0019740) |
0.2 | 1.2 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
0.2 | 1.6 | GO:0009228 | thiamine biosynthetic process(GO:0009228) thiamine-containing compound biosynthetic process(GO:0042724) |
0.2 | 0.8 | GO:0032056 | positive regulation of translation in response to stress(GO:0032056) |
0.2 | 0.4 | GO:0042148 | strand invasion(GO:0042148) |
0.2 | 0.2 | GO:1900182 | positive regulation of protein localization to nucleus(GO:1900182) positive regulation of cellular protein localization(GO:1903829) |
0.2 | 0.7 | GO:0051654 | establishment of mitochondrion localization(GO:0051654) |
0.2 | 0.9 | GO:0070124 | mitochondrial translational initiation(GO:0070124) |
0.2 | 0.5 | GO:0006000 | fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.2 | 0.7 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
0.2 | 3.5 | GO:0015914 | phospholipid transport(GO:0015914) |
0.2 | 2.2 | GO:0006081 | cellular aldehyde metabolic process(GO:0006081) |
0.2 | 2.4 | GO:0042493 | response to drug(GO:0042493) |
0.2 | 3.4 | GO:0016579 | protein deubiquitination(GO:0016579) |
0.2 | 2.0 | GO:0046854 | lipid phosphorylation(GO:0046834) phosphatidylinositol phosphorylation(GO:0046854) |
0.2 | 0.2 | GO:0061187 | regulation of chromatin silencing at rDNA(GO:0061187) |
0.1 | 4.3 | GO:0098660 | inorganic ion transmembrane transport(GO:0098660) |
0.1 | 0.4 | GO:0030491 | heteroduplex formation(GO:0030491) |
0.1 | 1.4 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
0.1 | 1.9 | GO:0000147 | actin cortical patch assembly(GO:0000147) actin cortical patch organization(GO:0044396) |
0.1 | 0.1 | GO:0000709 | meiotic joint molecule formation(GO:0000709) |
0.1 | 0.9 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
0.1 | 1.2 | GO:0009651 | response to salt stress(GO:0009651) |
0.1 | 0.8 | GO:0046686 | response to cadmium ion(GO:0046686) |
0.1 | 0.3 | GO:0051156 | glucose 6-phosphate metabolic process(GO:0051156) |
0.1 | 0.3 | GO:0072530 | cytosine transport(GO:0015856) purine-containing compound transmembrane transport(GO:0072530) |
0.1 | 0.6 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
0.1 | 0.3 | GO:0042173 | regulation of sporulation resulting in formation of a cellular spore(GO:0042173) |
0.1 | 0.2 | GO:0042710 | biofilm formation(GO:0042710) |
0.1 | 1.4 | GO:0000753 | cell morphogenesis involved in conjugation with cellular fusion(GO:0000753) |
0.1 | 0.9 | GO:0072348 | sulfur compound transport(GO:0072348) |
0.1 | 1.2 | GO:0030952 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) establishment or maintenance of cytoskeleton polarity(GO:0030952) |
0.1 | 0.3 | GO:0071825 | lipid tube assembly(GO:0060988) protein-lipid complex assembly(GO:0065005) protein-lipid complex subunit organization(GO:0071825) |
0.1 | 0.3 | GO:0072479 | cellular response to biotic stimulus(GO:0071216) response to cell cycle checkpoint signaling(GO:0072396) response to mitotic cell cycle checkpoint signaling(GO:0072414) response to spindle checkpoint signaling(GO:0072417) response to mitotic spindle checkpoint signaling(GO:0072476) response to mitotic cell cycle spindle assembly checkpoint signaling(GO:0072479) response to spindle assembly checkpoint signaling(GO:0072485) negative regulation of protein import into nucleus during spindle assembly checkpoint(GO:1901925) |
0.1 | 2.5 | GO:0006312 | mitotic recombination(GO:0006312) |
0.1 | 0.8 | GO:0051181 | cofactor transport(GO:0051181) |
0.1 | 1.3 | GO:0006885 | regulation of pH(GO:0006885) |
0.1 | 0.3 | GO:0046466 | sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466) |
0.1 | 0.8 | GO:0031167 | rRNA methylation(GO:0031167) |
0.1 | 0.3 | GO:0019748 | secondary metabolic process(GO:0019748) |
0.1 | 0.2 | GO:0009415 | response to water(GO:0009415) cellular response to water stimulus(GO:0071462) |
0.1 | 1.7 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
0.1 | 0.3 | GO:0018206 | N-terminal peptidyl-methionine acetylation(GO:0017196) peptidyl-methionine modification(GO:0018206) |
0.1 | 0.2 | GO:0044209 | AMP salvage(GO:0044209) |
0.1 | 0.7 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
0.1 | 0.6 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.1 | 0.7 | GO:0071709 | ascospore-type prospore membrane assembly(GO:0032120) membrane biogenesis(GO:0044091) membrane assembly(GO:0071709) |
0.1 | 0.2 | GO:0032874 | positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304) |
0.1 | 0.9 | GO:0000272 | polysaccharide catabolic process(GO:0000272) |
0.1 | 0.9 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
0.1 | 0.6 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) copper ion homeostasis(GO:0055070) |
0.1 | 0.6 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
0.1 | 0.6 | GO:0006078 | (1->6)-beta-D-glucan biosynthetic process(GO:0006078) |
0.1 | 0.3 | GO:0009395 | phospholipid catabolic process(GO:0009395) |
0.1 | 0.1 | GO:0070932 | histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933) |
0.1 | 0.4 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
0.1 | 0.1 | GO:0042732 | D-xylose metabolic process(GO:0042732) |
0.1 | 1.2 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.1 | 0.3 | GO:0031333 | negative regulation of protein complex assembly(GO:0031333) |
0.1 | 5.7 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.1 | 0.3 | GO:0000023 | maltose metabolic process(GO:0000023) |
0.1 | 5.5 | GO:0007005 | mitochondrion organization(GO:0007005) |
0.1 | 1.4 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.9 | GO:0048278 | vesicle docking(GO:0048278) |
0.0 | 0.9 | GO:0001300 | chronological cell aging(GO:0001300) |
0.0 | 0.4 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.3 | GO:0030042 | actin filament depolymerization(GO:0030042) |
0.0 | 0.1 | GO:0034059 | response to anoxia(GO:0034059) cellular response to anoxia(GO:0071454) |
0.0 | 0.2 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
0.0 | 0.3 | GO:0010526 | negative regulation of transposition, RNA-mediated(GO:0010526) negative regulation of transposition(GO:0010529) |
0.0 | 0.2 | GO:0007532 | regulation of mating-type specific transcription, DNA-templated(GO:0007532) |
0.0 | 0.5 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
0.0 | 1.6 | GO:0044843 | G1/S transition of mitotic cell cycle(GO:0000082) cell cycle G1/S phase transition(GO:0044843) |
0.0 | 0.2 | GO:0006661 | phosphatidylinositol biosynthetic process(GO:0006661) |
0.0 | 0.5 | GO:0009267 | cellular response to starvation(GO:0009267) |
0.0 | 0.1 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
0.0 | 0.1 | GO:0019933 | cAMP-mediated signaling(GO:0019933) cyclic-nucleotide-mediated signaling(GO:0019935) |
0.0 | 0.0 | GO:1900544 | positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544) |
0.0 | 0.1 | GO:0006531 | aspartate metabolic process(GO:0006531) |
0.0 | 0.3 | GO:0000742 | karyogamy involved in conjugation with cellular fusion(GO:0000742) |
0.0 | 0.1 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.0 | 0.1 | GO:0043605 | allantoin metabolic process(GO:0000255) allantoin catabolic process(GO:0000256) cellular amide catabolic process(GO:0043605) |
0.0 | 0.1 | GO:0006048 | UDP-N-acetylglucosamine metabolic process(GO:0006047) UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
0.0 | 0.5 | GO:0006200 | obsolete ATP catabolic process(GO:0006200) |
0.0 | 0.3 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
0.0 | 0.1 | GO:0009756 | cellular glucose homeostasis(GO:0001678) carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333) |
0.0 | 0.2 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.0 | 0.2 | GO:0032509 | endosome transport via multivesicular body sorting pathway(GO:0032509) |
0.0 | 0.1 | GO:0010528 | regulation of transposition(GO:0010528) |
0.0 | 1.4 | GO:0031505 | fungal-type cell wall organization(GO:0031505) |
0.0 | 0.1 | GO:0046341 | CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341) |
0.0 | 0.1 | GO:0016925 | protein sumoylation(GO:0016925) |
0.0 | 0.0 | GO:0006086 | acetyl-CoA biosynthetic process(GO:0006085) acetyl-CoA biosynthetic process from pyruvate(GO:0006086) |
0.0 | 0.1 | GO:0007039 | protein catabolic process in the vacuole(GO:0007039) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.7 | 28.7 | GO:0045257 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
3.9 | 34.7 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277) |
3.6 | 10.8 | GO:0045265 | mitochondrial proton-transporting ATP synthase, stator stalk(GO:0000274) proton-transporting ATP synthase, stator stalk(GO:0045265) |
2.5 | 14.8 | GO:0045263 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
2.3 | 11.4 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
2.2 | 19.4 | GO:0098803 | mitochondrial respiratory chain(GO:0005746) respiratory chain complex(GO:0098803) |
1.4 | 8.2 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
1.0 | 2.9 | GO:0031166 | integral component of vacuolar membrane(GO:0031166) |
0.6 | 3.2 | GO:0044233 | ERMES complex(GO:0032865) ER-mitochondrion membrane contact site(GO:0044233) |
0.6 | 2.5 | GO:0000148 | 1,3-beta-D-glucan synthase complex(GO:0000148) |
0.6 | 4.2 | GO:0034657 | GID complex(GO:0034657) |
0.6 | 2.4 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.5 | 8.7 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.5 | 5.1 | GO:0030677 | ribonuclease P complex(GO:0030677) |
0.5 | 1.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.4 | 5.2 | GO:0005619 | ascospore wall(GO:0005619) |
0.4 | 7.0 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307) |
0.4 | 6.4 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
0.3 | 3.0 | GO:0000795 | synaptonemal complex(GO:0000795) |
0.3 | 2.3 | GO:0000112 | nucleotide-excision repair factor 3 complex(GO:0000112) |
0.3 | 2.0 | GO:0009277 | fungal-type cell wall(GO:0009277) |
0.3 | 0.9 | GO:0005784 | Sec61 translocon complex(GO:0005784) |
0.3 | 1.2 | GO:0032116 | SMC loading complex(GO:0032116) |
0.3 | 0.9 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.3 | 0.9 | GO:0031422 | RecQ helicase-Topo III complex(GO:0031422) |
0.3 | 0.9 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
0.3 | 1.1 | GO:0030287 | cell wall-bounded periplasmic space(GO:0030287) |
0.3 | 0.5 | GO:0032126 | eisosome(GO:0032126) |
0.2 | 1.4 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.2 | 0.7 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.2 | 10.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.2 | 10.8 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.2 | 1.2 | GO:0031932 | TORC2 complex(GO:0031932) |
0.2 | 0.6 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.2 | 20.7 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.2 | 2.2 | GO:0098552 | side of membrane(GO:0098552) cytoplasmic side of membrane(GO:0098562) |
0.2 | 0.6 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 2.2 | GO:0033698 | Rpd3L complex(GO:0033698) |
0.1 | 2.5 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.1 | 0.5 | GO:0005825 | half bridge of spindle pole body(GO:0005825) |
0.1 | 0.8 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.1 | 0.3 | GO:0000813 | ESCRT I complex(GO:0000813) |
0.1 | 0.2 | GO:0016363 | nuclear matrix(GO:0016363) |
0.1 | 4.3 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.1 | 3.5 | GO:0005576 | extracellular region(GO:0005576) |
0.1 | 1.0 | GO:0005769 | early endosome(GO:0005769) |
0.1 | 0.4 | GO:0016587 | Isw1 complex(GO:0016587) |
0.1 | 0.5 | GO:0035361 | Cul8-RING ubiquitin ligase complex(GO:0035361) |
0.1 | 53.4 | GO:0005739 | mitochondrion(GO:0005739) |
0.1 | 0.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.1 | 1.1 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.1 | 22.9 | GO:0005886 | plasma membrane(GO:0005886) |
0.1 | 0.4 | GO:0005775 | fungal-type vacuole lumen(GO:0000328) vacuolar lumen(GO:0005775) |
0.1 | 1.4 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
0.1 | 6.6 | GO:0098852 | fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852) |
0.1 | 2.5 | GO:0030479 | actin cortical patch(GO:0030479) endocytic patch(GO:0061645) |
0.1 | 0.2 | GO:0070210 | Rpd3L-Expanded complex(GO:0070210) |
0.1 | 0.6 | GO:0034399 | nuclear periphery(GO:0034399) |
0.1 | 0.1 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.0 | 0.8 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
0.0 | 0.1 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 0.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.4 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 0.4 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 0.4 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
0.0 | 0.1 | GO:0000812 | Swr1 complex(GO:0000812) |
0.0 | 0.1 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
0.0 | 0.5 | GO:0043332 | mating projection tip(GO:0043332) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.7 | 28.7 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
3.7 | 18.3 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
3.5 | 34.7 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
3.4 | 10.1 | GO:0005302 | L-tyrosine transmembrane transporter activity(GO:0005302) L-glutamine transmembrane transporter activity(GO:0015186) L-isoleucine transmembrane transporter activity(GO:0015188) branched-chain amino acid transmembrane transporter activity(GO:0015658) |
3.3 | 9.9 | GO:0016289 | CoA hydrolase activity(GO:0016289) |
2.6 | 28.5 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
2.6 | 7.7 | GO:0004108 | citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440) |
2.5 | 10.1 | GO:0005537 | mannose binding(GO:0005537) |
2.5 | 9.9 | GO:0015603 | siderophore transmembrane transporter activity(GO:0015343) iron chelate transmembrane transporter activity(GO:0015603) siderophore transporter activity(GO:0042927) |
2.4 | 9.8 | GO:0016885 | ligase activity, forming carbon-carbon bonds(GO:0016885) |
2.4 | 19.4 | GO:0016679 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
2.2 | 8.7 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
2.1 | 6.2 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
1.9 | 5.8 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
1.9 | 7.6 | GO:0004396 | hexokinase activity(GO:0004396) |
1.7 | 6.8 | GO:0005347 | ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217) |
1.7 | 6.8 | GO:0015146 | pentose transmembrane transporter activity(GO:0015146) |
1.4 | 4.2 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
1.4 | 6.9 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
1.3 | 3.9 | GO:0016872 | intramolecular lyase activity(GO:0016872) |
1.1 | 3.4 | GO:0004564 | beta-fructofuranosidase activity(GO:0004564) sucrose alpha-glucosidase activity(GO:0004575) |
1.1 | 3.3 | GO:1901474 | azole transmembrane transporter activity(GO:1901474) |
1.1 | 7.6 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
1.1 | 6.5 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
1.0 | 8.4 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
1.0 | 4.2 | GO:0004112 | cyclic-nucleotide phosphodiesterase activity(GO:0004112) |
0.9 | 2.8 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.9 | 10.8 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
0.8 | 2.5 | GO:0003843 | 1,3-beta-D-glucan synthase activity(GO:0003843) |
0.7 | 1.5 | GO:0004448 | isocitrate dehydrogenase activity(GO:0004448) |
0.7 | 6.0 | GO:0015205 | nucleobase transmembrane transporter activity(GO:0015205) |
0.7 | 3.3 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.6 | 8.2 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.6 | 4.2 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
0.6 | 3.6 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.6 | 1.8 | GO:0008972 | hydroxymethylpyrimidine kinase activity(GO:0008902) phosphomethylpyrimidine kinase activity(GO:0008972) |
0.6 | 2.2 | GO:0003916 | DNA topoisomerase activity(GO:0003916) |
0.6 | 2.2 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.5 | 2.6 | GO:0018456 | aryl-alcohol dehydrogenase (NAD+) activity(GO:0018456) |
0.5 | 2.6 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.5 | 5.1 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.5 | 1.9 | GO:0016417 | S-acyltransferase activity(GO:0016417) |
0.5 | 1.4 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.5 | 1.8 | GO:0004737 | pyruvate decarboxylase activity(GO:0004737) |
0.4 | 1.7 | GO:0000772 | mating pheromone activity(GO:0000772) pheromone activity(GO:0005186) |
0.4 | 1.1 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
0.4 | 1.1 | GO:0015927 | alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927) |
0.4 | 1.1 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) |
0.3 | 0.3 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
0.3 | 0.9 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.3 | 1.5 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
0.3 | 1.4 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.3 | 0.8 | GO:0004629 | phospholipase C activity(GO:0004629) |
0.3 | 1.6 | GO:0004030 | aldehyde dehydrogenase (NAD) activity(GO:0004029) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.3 | 1.3 | GO:0070403 | NAD+ binding(GO:0070403) |
0.3 | 7.0 | GO:0004857 | enzyme inhibitor activity(GO:0004857) |
0.2 | 2.0 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.2 | 0.9 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
0.2 | 1.6 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.2 | 2.2 | GO:0035064 | methylated histone binding(GO:0035064) |
0.2 | 2.1 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
0.2 | 1.4 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.2 | 0.8 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.2 | 0.6 | GO:0032139 | dinucleotide insertion or deletion binding(GO:0032139) |
0.2 | 0.8 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
0.2 | 3.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
0.2 | 1.1 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.2 | 1.2 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.2 | 0.9 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
0.2 | 0.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.2 | 1.2 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.2 | 1.3 | GO:0000149 | SNARE binding(GO:0000149) |
0.2 | 0.7 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.2 | 1.6 | GO:0015238 | drug transmembrane transporter activity(GO:0015238) |
0.2 | 0.5 | GO:0055106 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) ubiquitin-protein transferase activator activity(GO:0097027) |
0.2 | 0.8 | GO:0005354 | galactose transmembrane transporter activity(GO:0005354) |
0.2 | 2.4 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
0.1 | 1.8 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
0.1 | 0.9 | GO:1901682 | sulfur compound transmembrane transporter activity(GO:1901682) |
0.1 | 1.1 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
0.1 | 6.4 | GO:0016410 | N-acyltransferase activity(GO:0016410) |
0.1 | 2.5 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.1 | 0.4 | GO:0000150 | recombinase activity(GO:0000150) |
0.1 | 0.3 | GO:0042947 | alpha-glucoside transmembrane transporter activity(GO:0015151) glucoside transmembrane transporter activity(GO:0042947) |
0.1 | 0.1 | GO:0000104 | succinate dehydrogenase activity(GO:0000104) |
0.1 | 2.1 | GO:0015297 | antiporter activity(GO:0015297) |
0.1 | 0.6 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
0.1 | 1.2 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
0.1 | 0.5 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.1 | 0.5 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
0.1 | 1.6 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.1 | 0.6 | GO:0017022 | myosin binding(GO:0017022) |
0.1 | 0.3 | GO:0008897 | holo-[acyl-carrier-protein] synthase activity(GO:0008897) |
0.1 | 0.3 | GO:0001129 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) |
0.1 | 1.3 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.1 | 0.5 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
0.1 | 1.3 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.1 | 0.9 | GO:0016684 | peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684) |
0.1 | 0.4 | GO:0004338 | glucan exo-1,3-beta-glucosidase activity(GO:0004338) |
0.1 | 0.8 | GO:0010181 | FMN binding(GO:0010181) |
0.1 | 0.2 | GO:0008106 | aldo-keto reductase (NADP) activity(GO:0004033) alcohol dehydrogenase (NADP+) activity(GO:0008106) |
0.1 | 0.3 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.1 | 0.8 | GO:0051184 | cofactor transporter activity(GO:0051184) |
0.1 | 5.7 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.1 | 0.8 | GO:0015662 | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662) |
0.1 | 1.4 | GO:0016836 | hydro-lyase activity(GO:0016836) |
0.1 | 0.5 | GO:0098847 | single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847) |
0.1 | 1.4 | GO:0015399 | primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) |
0.1 | 0.2 | GO:0004026 | alcohol O-acetyltransferase activity(GO:0004026) alcohol O-acyltransferase activity(GO:0034318) |
0.1 | 0.4 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.1 | 0.7 | GO:0038023 | transmembrane signaling receptor activity(GO:0004888) signaling receptor activity(GO:0038023) transmembrane receptor activity(GO:0099600) |
0.1 | 0.7 | GO:0005507 | copper ion binding(GO:0005507) |
0.1 | 0.1 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
0.1 | 1.5 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.0 | 0.1 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.0 | 0.8 | GO:0008374 | O-acyltransferase activity(GO:0008374) |
0.0 | 0.1 | GO:0032183 | SUMO binding(GO:0032183) |
0.0 | 0.5 | GO:0045182 | translation regulator activity(GO:0045182) |
0.0 | 0.1 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) TFIIIC-class transcription factor binding(GO:0001156) |
0.0 | 0.1 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.0 | 0.4 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.1 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
0.0 | 0.1 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.0 | 0.4 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
0.0 | 0.1 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H3-K9 specific)(GO:0032129) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970) NAD-dependent histone deacetylase activity (H3-K18 specific)(GO:0097372) |
0.0 | 0.1 | GO:0005102 | receptor binding(GO:0005102) |
0.0 | 0.2 | GO:0003713 | transcription coactivator activity(GO:0003713) |
0.0 | 0.1 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
0.0 | 0.6 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 0.0 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.0 | 0.3 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
0.0 | 0.2 | GO:0005509 | calcium ion binding(GO:0005509) |
0.0 | 0.1 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
0.0 | 0.3 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
0.0 | 0.3 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.1 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.0 | 0.1 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.7 | PID FOXO PATHWAY | FoxO family signaling |
0.3 | 1.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.3 | 0.9 | PID NOTCH PATHWAY | Notch signaling pathway |
0.1 | 0.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.1 | 0.2 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
0.1 | 127.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.1 | 0.2 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
0.1 | 0.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 0.2 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 0.1 | PID ATR PATHWAY | ATR signaling pathway |
0.0 | 0.1 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 5.0 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
0.7 | 6.5 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.3 | 0.8 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
0.2 | 0.6 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
0.2 | 0.6 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.1 | 0.7 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
0.1 | 126.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.1 | 0.2 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
0.1 | 0.2 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
0.0 | 0.5 | REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | Genes involved in Post-translational protein modification |
0.0 | 0.2 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |