Results for RCS1
Z-value: 3.75
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YOR382W Show fit | 67.57 |
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
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| YOR383C Show fit | 58.99 |
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
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| YDR536W Show fit | 49.64 |
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock |
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| YKL217W Show fit | 43.19 |
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose |
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| YIL057C Show fit | 41.84 |
Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose |
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| YDL210W Show fit | 36.77 |
Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane |
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| YHR139C Show fit | 36.75 |
Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall |
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| YLR327C Show fit | 36.61 |
Protein of unknown function that associates with ribosomes |
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| YMR175W Show fit | 32.97 |
Protein of unknown function whose expression is induced by osmotic stress |
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| YBL049W Show fit | 29.53 |
Protein of unknown function, has homology to kinase Snf7p; not required for growth on nonfermentable carbon sources; essential for viability in stationary phase |
Network of associatons between targets according to the STRING database.
First level regulatory network of RCS1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 27.1 | 216.5 | GO:0015891 | siderophore transport(GO:0015891) |
| 13.1 | 52.4 | GO:0006848 | pyruvate transport(GO:0006848) |
| 9.9 | 49.6 | GO:0015793 | glycerol transport(GO:0015793) |
| 4.6 | 41.0 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 1.0 | 38.4 | GO:0070591 | ascospore wall assembly(GO:0030476) spore wall assembly(GO:0042244) spore wall biogenesis(GO:0070590) ascospore wall biogenesis(GO:0070591) fungal-type cell wall assembly(GO:0071940) |
| 7.9 | 31.7 | GO:0015847 | putrescine transport(GO:0015847) |
| 7.5 | 30.1 | GO:0071462 | response to water(GO:0009415) cellular response to water stimulus(GO:0071462) |
| 1.1 | 29.8 | GO:0055072 | iron ion homeostasis(GO:0055072) |
| 6.6 | 26.3 | GO:0000949 | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway(GO:0000949) |
| 1.7 | 26.2 | GO:0031321 | ascospore-type prospore assembly(GO:0031321) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 124.4 | GO:0005886 | plasma membrane(GO:0005886) |
| 0.9 | 101.8 | GO:0098852 | fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852) |
| 1.9 | 90.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.5 | 72.1 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 1.0 | 71.8 | GO:0010008 | endosome membrane(GO:0010008) |
| 4.6 | 60.2 | GO:0005619 | ascospore wall(GO:0005619) |
| 0.1 | 41.3 | GO:0005739 | mitochondrion(GO:0005739) |
| 3.2 | 28.9 | GO:0045277 | mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277) |
| 1.3 | 28.7 | GO:0042763 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
| 5.4 | 27.1 | GO:0005640 | nuclear outer membrane(GO:0005640) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 25.9 | 129.6 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 17.9 | 71.6 | GO:0015343 | siderophore transmembrane transporter activity(GO:0015343) iron chelate transmembrane transporter activity(GO:0015603) siderophore transporter activity(GO:0042927) |
| 6.7 | 60.1 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
| 0.5 | 32.5 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 2.9 | 28.9 | GO:0016675 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 2.6 | 28.8 | GO:0015293 | symporter activity(GO:0015293) |
| 0.5 | 28.4 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.5 | 27.1 | GO:0000982 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) |
| 6.6 | 26.3 | GO:0004737 | pyruvate decarboxylase activity(GO:0004737) |
| 1.0 | 24.2 | GO:0003684 | damaged DNA binding(GO:0003684) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 770.8 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 4.8 | 14.3 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 3.5 | 13.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 1.2 | 9.5 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 3.1 | 9.4 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 3.1 | 6.2 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 1.9 | 5.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.9 | 5.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.9 | 1.8 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.7 | 1.4 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 770.8 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.9 | 10.7 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 3.4 | 10.1 | REACTOME PI3K EVENTS IN ERBB2 SIGNALING | Genes involved in PI3K events in ERBB2 signaling |
| 2.5 | 10.0 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.9 | 8.1 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.5 | 4.7 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.6 | 3.8 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 1.2 | 3.7 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.2 | 2.9 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.7 | 2.2 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |