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Results for RDS1

Z-value: 0.73

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Transcription factors associated with RDS1

Gene Symbol Gene ID Gene Info
RDS1
S000000703 Putative zinc cluster transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RDS1YCR106W-0.145.0e-01Click!

Activity profile of RDS1 motif

Sorted Z-values of RDS1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YCL025C 3.54
AGP1
Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)
YKL217W 2.90
JEN1
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose
YML089C 2.36 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage
YJL089W 2.35
SIP4
C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus
YBR230C 2.16
OM14
Integral mitochondrial outer membrane protein; abundance is decreased in cells grown in glucose relative to other carbon sources; appears to contain 3 alpha-helical transmembrane segments; ORF encodes a 97-basepair intron
YDL210W 2.12
UGA4
Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane
YDR536W 2.11
STL1
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock
YJL133C-A 1.99 Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YOL131W 1.89 Putative protein of unknown function
YGR236C 1.75
SPG1
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YML042W 1.55
CAT2
Carnitine acetyl-CoA transferase present in both mitochondria and peroxisomes, transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes
YAL054C 1.53
ACS1
Acetyl-coA synthetase isoform which, along with Acs2p, is the nuclear source of acetyl-coA for histone acetlyation; expressed during growth on nonfermentable carbon sources and under aerobic conditions
YML090W 1.52 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YML089C; exhibits growth defect on a non-fermentable (respiratory) carbon source
YNL144C 1.52 Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YNL144C is not an essential gene
YPR065W 1.48
ROX1
Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity
YNL179C 1.46 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; deletion in cyr1 mutant results in loss of stress resistance
YLR296W 1.44 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPR127W 1.41 Putative protein of unknown function; expression is activated by transcription factor YRM1/YOR172W; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus
YKL016C 1.39
ATP7
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
YNL180C 1.37
RHO5
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity
YPR036W-A 1.37 Protein of unknown function; transcription is regulated by Pdr1p
YBL015W 1.34
ACH1
Acetyl-coA hydrolase, primarily localized to mitochondria; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth
YNR002C 1.30
ATO2
Putative transmembrane protein involved in export of ammonia, a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Ady2p and Y. lipolytica Gpr1p
YLR295C 1.27
ATP14
Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
YJR078W 1.25
BNA2
Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p and Aft2p
YML091C 1.25
RPM2
Protein subunit of mitochondrial RNase P, has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus
YMR194C-B 1.20 Putative protein of unknown function
YAL039C 1.18
CYC3
Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)
YKL031W 1.15 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species
YNL305C 1.12 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL305C is not an essential gene
YLR327C 1.09
TMA10
Protein of unknown function that associates with ribosomes
YPL017C 1.06
IRC15
Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family, required for accurate meiotic chromosome segregation; null mutant displays increased levels of spontaneous Rad52 foci
YMR272C 1.03
SCS7
Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth
YNL142W 1.02
MEP2
Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation
YBR201C-A 1.00 Putative protein of unknown function
YGL184C 0.99
STR3
Cystathionine beta-lyase, converts cystathionine into homocysteine
YMR107W 0.99
SPG4
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources
YNL143C 0.97 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPR030W 0.96
CSR2
Nuclear protein with a potential regulatory role in utilization of galactose and nonfermentable carbon sources; overproduction suppresses the lethality at high temperature of a chs5 spa2 double null mutation; potential Cdc28p substrate
YOR152C 0.94 Putative protein of unknown function; has no similarity to any known protein; YOR152C is not an essential gene
YDR530C 0.93
APA2
Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase II (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa1p
YKL109W 0.92
HAP4
Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex
YAR035W 0.92
YAT1
Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated
YJL088W 0.90
ARG3
Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the sixth step in the biosynthesis of the arginine precursor ornithine
YDR379C-A 0.89 Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
YJL045W 0.89 Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner
YFL024C 0.88
EPL1
Component of NuA4, which is an essential histone H4/H2A acetyltransferase complex; homologous to Drosophila Enhancer of Polycomb
YKR009C 0.83
FOX2
Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities
YKR049C 0.81
FMP46
Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YHR217C 0.79 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; located in the telomeric region TEL08R.
YDR059C 0.79
UBC5
Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins, central component of the cellular stress response; expression is heat inducible
YJR077C 0.77
MIR1
Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2p under normal conditions; phosphorylated
YPL018W 0.77
CTF19
Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly
YFL021W 0.77
GAT1
Transcriptional activator of genes involved in nitrogen catabolite repression; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p
YNL055C 0.76
POR1
Mitochondrial porin (voltage-dependent anion channel), outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability; phosphorylated
YOR072W-A 0.75 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR072W; originally identified by fungal homology and RT-PCR
YDR231C 0.75
COX20
Mitochondrial inner membrane protein, required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase
YBR230W-A 0.75 Putative protein of unknown function
YOR065W 0.74
CYT1
Cytochrome c1, component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex
YMR195W 0.73
ICY1
Protein of unknown function, required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation
YPL054W 0.71
LEE1
Zinc-finger protein of unknown function
YOR072W 0.71 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOR072W-A; diploid deletion strains are methotrexate, paraquat and wortmannin sensitive
YFL062W 0.70
COS4
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
YLR004C 0.70
THI73
Putative plasma membrane permease proposed to be involved in carboxylic acid uptake and repressed by thiamine; substrate of Dbf2p/Mob1p kinase; transcription is altered if mitochondrial dysfunction occurs
YOR071C 0.69
NRT1
High-affinity nicotinamide riboside transporter; also transports thiamine with low affinity; shares sequence similarity with Thi7p and Thi72p; proposed to be involved in 5-fluorocytosine sensitivity
YLR297W 0.69 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YLR297W is not an essential gene; induced by treatment with 8-methoxypsoralen and UVA irradiation
YFL064C 0.69 Putative protein of unknown function
YPR192W 0.69
AQY1
Spore-specific water channel that mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance
YGR067C 0.68 Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p
YMR280C 0.67
CAT8
Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements
YHL036W 0.66
MUP3
Low affinity methionine permease, similar to Mup1p
YER053C 0.66
PIC2
Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Mir1p but less abundant than Mir1p under normal conditions; expression is induced at high temperature
YFL063W 0.66 Dubious open reading frame, based on available experimental and comparative sequence data
YDR406W 0.66
PDR15
Plasma membrane ATP binding cassette (ABC) transporter, multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element
YPL201C 0.65
YIG1
Protein that interacts with glycerol 3-phosphatase and plays a role in anaerobic glycerol production; localizes to the nucleus and cytosol
YJR045C 0.65
SSC1
Mitochondrial matrix ATPase, subunit of the presequence translocase-associated protein import motor (PAM) and of SceI endonuclease; involved in protein folding and translocation into the matrix; phosphorylated; member of HSP70 family
YOR140W 0.65
SFL1
Transcriptional repressor and activator; involved in repression of flocculation-related genes, and activation of stress responsive genes; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p
YDR374C 0.65 Putative protein of unknown function
YNL336W 0.62
COS1
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
YPR007C 0.62
REC8
Meiosis-specific component of sister chromatid cohesion complex; maintains cohesion between sister chromatids during meiosis I; maintains cohesion between centromeres of sister chromatids until meiosis II; homolog of S. pombe Rec8p
YBR050C 0.61
REG2
Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease
YHR009C 0.61 Putative protein of unknown function; not an essential gene
YIL125W 0.61
KGD1
Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA
YER091C-A 0.61 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YGL258W-A 0.61 Putative protein of unknown function
YOR211C 0.61
MGM1
Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required for normal morphology of cristae and for stability of Tim11p; homolog of human OPA1 involved in autosomal dominant optic atrophy
YPL061W 0.60
ALD6
Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress
YPL135W 0.60
ISU1
Conserved protein of the mitochondrial matrix, performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable
YOR139C 0.60 Hypothetical protein
YPR027C 0.60 Putative protein of unknown function
YOR084W 0.59
LPX1
Oleic acid-inducible, peroxisomal matrix localized lipase; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance; peroxisomal import is dependent on the PTS1 receptor, Pex5p and on self-interaction
YBR051W 0.59 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partiallly overlaps the REG2/YBR050C regulatory subunit of the Glc7p type-1 protein phosphatase
YHR139C 0.59
SPS100
Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall
YNL013C 0.58 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF HEF3/YNL014W
YML132W 0.58
COS3
Protein involved in salt resistance; interacts with sodium:hydrogen antiporter Nha1p; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
YKL032C 0.56
IXR1
Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b
YKL177W 0.56 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene STE3
YER162C 0.56
RAD4
Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human XPC protein
YOR338W 0.55 Putative protein of unknown function; YOR338W transcription is regulated by Azf1p and its transcript is a specific target of the G protein effector Scp160p; identified as being required for sporulation in a high-throughput mutant screen
YBL078C 0.55
ATG8
Conserved protein that is a component of autophagosomes and Cvt vesicles; undergoes C-terminal conjugation to phosphatidylethanolamine (PE), Atg8p-PE is anchored to membranes and may mediate membrane fusion during autophagosome formation
YDR247W 0.55
VHS1
Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p
YDR259C 0.54
YAP6
Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance
YBR224W 0.54 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TDP1
YGL208W 0.54
SIP2
One of three beta subunits of the Snf1 serine/threonine protein kinase complex involved in the response to glucose starvation; null mutants exhibit accelerated aging; N-myristoylprotein localized to the cytoplasm and the plasma membrane
YDR232W 0.53
HEM1
5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p
YER101C 0.53
AST2
Protein that may have a role in targeting of plasma membrane [H+]ATPase (Pma1p) to the plasma membrane, as suggested by analysis of genetic interactions
YHL024W 0.53
RIM4
Putative RNA-binding protein required for the expression of early and middle sporulation genes
YBL094C 0.53 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YBL095W
YEL009C-A 0.52 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YMR017W 0.52
SPO20
Meiosis-specific subunit of the t-SNARE complex, required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; SNAP-25 homolog
YOL025W 0.52
LAG2
Protein involved in determination of longevity; LAG2 gene is preferentially expressed in young cells; overexpression extends the mean and maximum life span of cells
YOR100C 0.51
CRC1
Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation
YNL036W 0.51
NCE103
Carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; involved in non-classical protein export pathway
YDR010C 0.51 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YOR138C 0.50
RUP1
Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin ligase; required for binding of Rsp5p to Ubp2p; contains an UBA domain
YNL160W 0.50
YGP1
Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p
YLL019C 0.50
KNS1
Nonessential putative protein kinase of unknown cellular role; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues
YPL200W 0.50
CSM4
Protein required for accurate chromosome segregation during meiosis
YBR105C 0.50
VID24
Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; involved in proteasome-dependent catabolite degradation of FBPase
YLR193C 0.49
UPS1
Mitochondrial intermembrane space protein that regulates alternative processing and sorting of Mgm1p and other proteins; required for normal mitochondrial morphology; ortholog of human PRELI
YJR048W 0.49
CYC1
Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration
YOR220W 0.48
RCN2
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS
YFR034W-A 0.48 Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YFR035C; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching
YAR019W-A 0.48 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YKL093W 0.47
MBR1
Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants
YDL199C 0.47 Putative transporter, member of the sugar porter family
YDR269C 0.47 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YEL010W 0.47 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YPR064W 0.47 Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data
YIL059C 0.47 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YIL060W
YKL178C 0.47
STE3
Receptor for a factor receptor, transcribed in alpha cells and required for mating by alpha cells, couples to MAP kinase cascade to mediate pheromone response; ligand bound receptors are endocytosed and recycled to the plasma membrane; GPCR
YIL033C 0.46
BCY1
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation
YKL163W 0.46
PIR3
O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway
YBR250W 0.46
SPO23
Protein of unknown function; associates with meiosis-specific protein Spo1p
YHR218W 0.46 Helicase-like protein encoded within the telomeric Y' element
YDL174C 0.46
DLD1
D-lactate dehydrogenase, oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane
YIR027C 0.45
DAL1
Allantoinase, converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression
YLR394W 0.45
CST9
SUMO E3 ligase; required for synaptonemal complex formation; localizes to synapsis initiation sites on meiotic chromosomes; potential Cdc28p substrate
YBR117C 0.45
TKL2
Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
YER015W 0.45
FAA2
Long chain fatty acyl-CoA synthetase; accepts a wider range of acyl chain lengths than Faa1p, preferring C9:0-C13:0; involved in the activation of endogenous pools of fatty acids
YOR316C-A 0.45 Putative protein of unknown function; identified by fungal homology and RT-PCR
YBR223C 0.45
TDP1
Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3'-phosphotyrosyl bonds to generate 3'-phosphate DNA and tyrosine, involved in the repair of DNA lesions created by topoisomerase I
YEL072W 0.44
RMD6
Protein required for sporulation
YBR183W 0.43
YPC1
Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance
YDL181W 0.42
INH1
Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase; inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p; has similarity to Stf1p; has a calmodulin-binding motif and binds calmodulin in vitro
YKL067W 0.42
YNK1
Nucleoside diphosphate kinase, catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate
YDR359C 0.42
EAF1
Component of the NuA4 histone acetyltransferase complex; required for initiation of pre-meiotic DNA replication, probably due to its requirement for significant expression of IME1
YML133C 0.42 Putative protein of unknown function with similarity to helicases; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YML133C contains an intron
YBR225W 0.42 Putative protein of unknown function; non-essential gene identified in a screen for mutants affected in mannosylphophorylation of cell wall components
YGL163C 0.41
RAD54
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family
YJL163C 0.41 Putative protein of unknown function
YOR345C 0.41 Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene REV1; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2
YDR461C-A 0.41 Putative protein of unknown function
YOR346W 0.41
REV1
Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA
YFR053C 0.41
HXK1
Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p
YPL089C 0.40
RLM1
MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p
YMR056C 0.40
AAC1
Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; phosphorylated; Aac1p is a minor isoform while Pet9p is the major ADP/ATP translocator
YNL125C 0.40
ESBP6
Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane
YJL152W 0.40 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDR270W 0.39
CCC2
Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytosolic compartment; has similarity to human proteins involved in Menkes and Wilsons diseases
YAR019C 0.39
CDC15
Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p
YBR280C 0.39
SAF1
F-Box protein involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1
YKL133C 0.39 Putative protein of unknown function
YHR198C 0.39
AIM18
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
YAR023C 0.39 Putative integral membrane protein, member of DUP240 gene family
YBR035C 0.39
PDX3
Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism
YLL029W 0.38
FRA1
Protein involved in negative regulation of transcription of iron regulon; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; cytosolic; mutant fails to repress transcription of iron regulon and is defective in spore formation
YMR256C 0.38
COX7
Subunit VII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
YNL339C 0.38
YRF1-6
Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
YGR243W 0.38
FMP43
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YHR199C 0.38
AIM46
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
YLR047C 0.37
FRE8
Protein with sequence similarity to iron/copper reductases, involved in iron homeostasis; deletion mutant has iron deficiency/accumulation growth defects; expression increased in the absence of copper-responsive transcription factor Mac1p
YDR360W 0.37
OPI7
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene VID21/YDR359C.
YFL052W 0.37 Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity
YLR184W 0.37 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDL222C 0.36
FMP45
Integral membrane protein localized to mitochondria (untagged protein) and eisosomes, immobile patches at the cortex associated with endocytosis; sporulation and sphingolipid content are altered in mutants; has homologs SUR7 and YNL194C
YPL230W 0.36
USV1
Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis
YDR092W 0.36
UBC13
Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus
YLL055W 0.36
YCT1
High-affinity cysteine-specific transporter with similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene
YOR064C 0.36
YNG1
Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3, has similarity to the human tumor suppressor ING1
YKL171W 0.36 Putative protein of unknown function; predicted protein kinase; implicated in proteasome function; epitope-tagged protein localizes to the cytoplasm
YHR082C 0.36
KSP1
Nonessential putative serine/threonine protein kinase of unknown cellular role; overproduction causes allele-specific suppression of the prp20-10 mutation
YEL020C 0.35 Hypothetical protein with low sequence identity to Pdc1p
YPL262W 0.35
FUM1
Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation; phosphorylated in mitochondria
YBR019C 0.34
GAL10
UDP-glucose-4-epimerase, catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes the conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers
YGL180W 0.34
ATG1
Protein serine/threonine kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for pre-autophagosome formation; during autophagy forms a complex with Atg13p and Atg17p
YPR124W 0.34
CTR1
High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels
YOR010C 0.34
TIR2
Putative cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; transcription is induced by cold shock and anaerobiosis
YBR016W 0.34 Plasma membrane protein of unknown function; has similarity to hydrophilins, which are hydrophilic, glycine-rich proteins involved in the adaptive response to hyperosmotic conditions
YDL196W 0.34 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame is located in promoter region of essential gene SEC31
YIL086C 0.33 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YIL087C 0.33
LRC2
Putative protein of unknown function; protein is detected in purified mitochondria in high-throughput studies; null mutant displays decreased mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
YNL196C 0.33
SLZ1
Sporulation-specific protein with a leucine zipper motif
YFL036W 0.33
RPO41
Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition
YJR115W 0.33 Putative protein of unknown function
YGR194C 0.33
XKS1
Xylulokinase, converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains
YBL099W 0.33
ATP1
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated
YLL046C 0.32
RNP1
Ribonucleoprotein that contains two RNA recognition motifs (RRM)
YIL058W 0.32 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YPL147W 0.32
PXA1
Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins

Network of associatons between targets according to the STRING database.

First level regulatory network of RDS1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0061414 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061413) positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061414)
0.8 2.5 GO:0009437 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.8 3.3 GO:0006848 pyruvate transport(GO:0006848)
0.5 2.0 GO:0015847 putrescine transport(GO:0015847)
0.5 1.5 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.4 1.2 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.4 1.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.4 2.7 GO:0006083 acetate metabolic process(GO:0006083)
0.3 1.6 GO:0015793 glycerol transport(GO:0015793)
0.3 0.9 GO:0015888 thiamine transport(GO:0015888)
0.3 1.6 GO:0042407 cristae formation(GO:0042407)
0.3 1.1 GO:0032079 positive regulation of deoxyribonuclease activity(GO:0032077) positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.3 0.8 GO:1900460 negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter(GO:1900460)
0.3 1.3 GO:0034627 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627)
0.2 1.0 GO:0019346 transsulfuration(GO:0019346)
0.2 0.7 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.2 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883) sodium ion homeostasis(GO:0055078)
0.2 0.8 GO:0015976 carbon utilization(GO:0015976)
0.2 1.0 GO:0006673 inositolphosphoceramide metabolic process(GO:0006673)
0.2 0.6 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.2 0.4 GO:0000101 sulfur amino acid transport(GO:0000101) neutral amino acid transport(GO:0015804)
0.2 0.7 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.2 0.7 GO:0015886 heme transport(GO:0015886)
0.2 0.5 GO:0051469 vesicle fusion with vacuole(GO:0051469)
0.2 0.3 GO:0006171 cAMP biosynthetic process(GO:0006171) cyclic nucleotide biosynthetic process(GO:0009190) cyclic purine nucleotide metabolic process(GO:0052652)
0.2 1.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 0.2 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.2 1.2 GO:0006591 ornithine metabolic process(GO:0006591)
0.1 0.7 GO:0044070 regulation of anion transport(GO:0044070)
0.1 0.6 GO:0045980 negative regulation of nucleotide metabolic process(GO:0045980)
0.1 0.4 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.1 1.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 2.7 GO:0019740 nitrogen utilization(GO:0019740)
0.1 0.9 GO:0009164 nucleoside catabolic process(GO:0009164) glycosyl compound catabolic process(GO:1901658)
0.1 0.4 GO:0046039 GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039)
0.1 1.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.4 GO:0051180 vitamin transport(GO:0051180)
0.1 1.8 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.4 GO:0010039 response to iron ion(GO:0010039) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) cellular response to iron ion(GO:0071281)
0.1 0.9 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.1 0.5 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.1 1.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.5 GO:0043200 response to amino acid(GO:0043200)
0.1 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.4 GO:0061416 regulation of transcription from RNA polymerase II promoter in response to salt stress(GO:0061416)
0.1 0.4 GO:0010994 free ubiquitin chain polymerization(GO:0010994)
0.1 0.2 GO:0008272 sulfate transport(GO:0008272)
0.1 0.7 GO:0000501 flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501)
0.1 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513)
0.1 0.5 GO:0051303 meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.1 0.2 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) regulation of membrane lipid metabolic process(GO:1905038)
0.1 3.4 GO:0098656 anion transmembrane transport(GO:0098656)
0.1 0.3 GO:0070583 spore membrane bending pathway(GO:0070583)
0.1 0.6 GO:0000255 allantoin metabolic process(GO:0000255) allantoin catabolic process(GO:0000256)
0.1 0.2 GO:0072353 cellular age-dependent response to reactive oxygen species(GO:0072353)
0.1 0.6 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.4 GO:0032105 negative regulation of macroautophagy(GO:0016242) negative regulation of response to external stimulus(GO:0032102) negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108)
0.1 0.6 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1 1.5 GO:0006101 tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101)
0.1 0.3 GO:2000911 positive regulation of lipid transport(GO:0032370) regulation of sterol transport(GO:0032371) positive regulation of sterol transport(GO:0032373) positive regulation of transmembrane transport(GO:0034764) regulation of sterol import by regulation of transcription from RNA polymerase II promoter(GO:0035968) positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter(GO:0035969) regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) regulation of sterol import(GO:2000909) positive regulation of sterol import(GO:2000911)
0.1 0.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.4 GO:0006279 premeiotic DNA replication(GO:0006279)
0.1 0.2 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.1 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.1 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061395) cellular response to arsenic-containing substance(GO:0071243)
0.1 0.3 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.8 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.1 0.4 GO:0046184 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) aldehyde biosynthetic process(GO:0046184)
0.1 0.1 GO:0071475 cellular response to salt stress(GO:0071472) cellular hyperosmotic salinity response(GO:0071475)
0.1 1.2 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 0.4 GO:0033313 meiotic cell cycle checkpoint(GO:0033313) meiotic recombination checkpoint(GO:0051598)
0.1 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 0.3 GO:0070096 mitochondrial outer membrane translocase complex assembly(GO:0070096)
0.1 0.2 GO:0015755 fructose transport(GO:0015755)
0.1 0.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.1 GO:0051222 positive regulation of protein transport(GO:0051222) positive regulation of establishment of protein localization(GO:1904951)
0.0 0.5 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.8 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0 0.1 GO:0061412 cellular response to amino acid starvation(GO:0034198) positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation(GO:0061412)
0.0 0.2 GO:0006771 riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231)
0.0 0.2 GO:0015851 nucleobase transport(GO:0015851)
0.0 0.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.2 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 1.2 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957)
0.0 0.0 GO:0018410 C-terminal protein amino acid modification(GO:0018410) post-translational protein modification(GO:0043687)
0.0 0.3 GO:0006638 neutral lipid metabolic process(GO:0006638) acylglycerol metabolic process(GO:0006639) triglyceride metabolic process(GO:0006641)
0.0 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.1 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.0 0.3 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.4 GO:0007121 bipolar cellular bud site selection(GO:0007121)
0.0 0.3 GO:0031321 ascospore-type prospore assembly(GO:0031321)
0.0 0.1 GO:0031055 chromatin remodeling at centromere(GO:0031055)
0.0 0.1 GO:0051101 positive regulation of DNA binding(GO:0043388) regulation of DNA binding(GO:0051101)
0.0 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.0 0.0 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0051292 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:0051322 anaphase(GO:0051322)
0.0 1.2 GO:0070726 cell wall assembly(GO:0070726)
0.0 0.2 GO:0000755 cytogamy(GO:0000755)
0.0 0.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.1 GO:0019543 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) short-chain fatty acid catabolic process(GO:0019626) propionate catabolic process, 2-methylcitrate cycle(GO:0019629)
0.0 0.1 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062) regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.2 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0033108 mitochondrial respiratory chain complex assembly(GO:0033108)
0.0 0.4 GO:0005978 glycogen biosynthetic process(GO:0005978)
0.0 0.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0009065 glutamine family amino acid catabolic process(GO:0009065)
0.0 0.1 GO:0000820 regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0 0.1 GO:0019320 hexose catabolic process(GO:0019320)
0.0 0.1 GO:0035459 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0001113 transcriptional open complex formation at RNA polymerase II promoter(GO:0001113)
0.0 0.1 GO:0000114 obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0006567 glycine biosynthetic process(GO:0006545) threonine catabolic process(GO:0006567)
0.0 0.2 GO:0019878 lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 0.1 GO:0006768 biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102)
0.0 0.1 GO:0016036 cellular response to phosphate starvation(GO:0016036)
0.0 0.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.2 GO:1902532 negative regulation of intracellular signal transduction(GO:1902532)
0.0 0.1 GO:0000272 polysaccharide catabolic process(GO:0000272)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.0 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.2 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.0 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 1.5 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0006598 polyamine catabolic process(GO:0006598)
0.0 0.2 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 0.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.0 GO:0097035 lipid translocation(GO:0034204) regulation of membrane lipid distribution(GO:0097035)
0.0 0.1 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0007323 peptide pheromone maturation(GO:0007323)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:0032048 cardiolipin metabolic process(GO:0032048)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0015758 glucose transport(GO:0015758)
0.0 0.3 GO:0022900 electron transport chain(GO:0022900)
0.0 0.2 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.1 GO:0009099 valine metabolic process(GO:0006573) valine biosynthetic process(GO:0009099)
0.0 0.0 GO:2001025 cellular response to drug(GO:0035690) regulation of response to drug(GO:2001023) positive regulation of response to drug(GO:2001025) regulation of cellular response to drug(GO:2001038) positive regulation of cellular response to drug(GO:2001040)
0.0 0.8 GO:0007005 mitochondrion organization(GO:0007005)
0.0 0.1 GO:0001558 regulation of cell growth(GO:0001558)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0045265 mitochondrial proton-transporting ATP synthase, stator stalk(GO:0000274) proton-transporting ATP synthase, stator stalk(GO:0045265)
0.3 1.6 GO:0045263 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.3 0.8 GO:0046930 pore complex(GO:0046930)
0.2 1.4 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.2 0.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 0.6 GO:0030061 mitochondrial crista(GO:0030061)
0.2 0.8 GO:0000817 COMA complex(GO:0000817)
0.2 0.6 GO:0000111 nucleotide-excision repair factor 2 complex(GO:0000111)
0.1 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 2.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.7 GO:0072380 ER membrane insertion complex(GO:0072379) TRC complex(GO:0072380)
0.1 1.2 GO:0030677 ribonuclease P complex(GO:0030677)
0.1 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0034657 GID complex(GO:0034657)
0.1 0.8 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.5 GO:0070469 respiratory chain(GO:0070469)
0.1 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.4 GO:0033100 NuA3 histone acetyltransferase complex(GO:0033100) H3 histone acetyltransferase complex(GO:0070775)
0.1 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 3.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 3.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.2 GO:0033309 SBF transcription complex(GO:0033309)
0.1 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0031422 RecQ helicase-Topo III complex(GO:0031422)
0.0 0.1 GO:0097042 extrinsic component of fungal-type vacuolar membrane(GO:0097042)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.6 GO:0005619 ascospore wall(GO:0005619)
0.0 0.1 GO:0000148 1,3-beta-D-glucan synthase complex(GO:0000148)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.0 GO:0042763 prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764)
0.0 4.8 GO:0000329 fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0000112 nucleotide-excision repair factor 3 complex(GO:0000112)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0000113 nucleotide-excision repair factor 4 complex(GO:0000113)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 2.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.0 GO:0005825 half bridge of spindle pole body(GO:0005825)
0.0 0.3 GO:0044455 mitochondrial membrane part(GO:0044455)
0.0 0.3 GO:0033698 Rpd3L complex(GO:0033698)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 10.4 GO:0005739 mitochondrion(GO:0005739)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0070274 RES complex(GO:0070274)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.0 GO:0070211 Snt2C complex(GO:0070211)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.8 GO:0005874 microtubule(GO:0005874)
0.0 0.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128) endocytic vesicle(GO:0030139) endocytic vesicle membrane(GO:0030666) clathrin-coated endocytic vesicle membrane(GO:0030669) clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0016514 SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.0 GO:0015295 solute:proton symporter activity(GO:0015295)
0.8 2.5 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406)
0.5 1.6 GO:0016208 AMP binding(GO:0016208)
0.5 2.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.4 1.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.3 3.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 0.8 GO:0015288 anion channel activity(GO:0005253) voltage-gated anion channel activity(GO:0008308) porin activity(GO:0015288) wide pore channel activity(GO:0022829)
0.2 0.8 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 0.5 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458)
0.2 1.6 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.2 0.5 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.2 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 0.6 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.2 1.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 0.6 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 2.5 GO:0046906 heme binding(GO:0020037) tetrapyrrole binding(GO:0046906)
0.1 0.6 GO:0005537 mannose binding(GO:0005537)
0.1 2.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.6 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.5 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.1 0.2 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.1 1.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.3 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.1 5.2 GO:0001228 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.4 GO:0004396 hexokinase activity(GO:0004396)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.3 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.4 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.1 0.2 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.7 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.7 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.1 1.0 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.1 0.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.2 GO:0008897 holo-[acyl-carrier-protein] synthase activity(GO:0008897)
0.1 1.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.5 GO:0015293 symporter activity(GO:0015293)
0.1 0.5 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.1 0.7 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.1 GO:0019903 phosphatase binding(GO:0019902) protein phosphatase binding(GO:0019903)
0.1 0.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.2 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.2 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.1 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 1.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0015440 peptide-transporting ATPase activity(GO:0015440) oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.4 GO:0016723 ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.4 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.9 GO:0016298 lipase activity(GO:0016298)
0.0 0.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.0 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0003843 1,3-beta-D-glucan synthase activity(GO:0003843)
0.0 0.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0003916 DNA topoisomerase activity(GO:0003916)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.1 GO:0001097 TFIIH-class transcription factor binding(GO:0001097)
0.0 0.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.0 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 0.0 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0004402 histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.0 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 0.2 PID FOXO PATHWAY FoxO family signaling
0.1 0.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID P73PATHWAY p73 transcription factor network
0.0 25.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.1 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 0.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 0.4 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 0.4 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 25.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis