Navigation
Downloads

Results for REI1

Z-value: 1.34

Motif logo

logo of

Transcription factors associated with REI1

Gene Symbol Gene ID Gene Info
REI1
S000000471 Cytoplasmic pre-60S factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
REI1YBR267W-0.203.3e-01Click!

Activity profile of REI1 motif

Sorted Z-values of REI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YDR133C 10.31 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C
YNR001W-A 9.11 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YFR055W 8.59
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YFR056C 8.57 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YPL014W 5.61 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus
YGR249W 5.37
MGA1
Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants
YBR126C 5.27
TPS1
Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway
YOL086C 5.18
ADH1
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
YGL179C 5.10
TOS3
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
YIL162W 4.94
SUC2
Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively
YOL085C 4.77 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOL085W-A
YBR126W-A 4.62 Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YBR126W-B; identified by gene-trapping, microarray analysis, and genome-wide homology searches
YHL021C 4.00
AIM17
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)
YPR160W 3.91
GPH1
Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway
YBR183W 3.86
YPC1
Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance
YKL096W-A 3.74
CWP2
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored
YDR516C 3.53
EMI2
Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1; required for sporulation; expression is regulated by glucose-repression transcription factors Mig1/2p
YER066C-A 3.48 Dubious open reading frame unlikely to encode a protein, partially overlaps uncharacterized ORF YER067W
YGR138C 3.45
TPO2
Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily
YHL003C 3.38
LAG1
Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p
YBR182C-A 3.25 Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
YNL160W 3.23
YGP1
Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p
YOL154W 3.02
ZPS1
Putative GPI-anchored protein; transcription is induced under low-zinc conditions, as mediated by the Zap1p transcription factor, and at alkaline pH
YGR192C 3.02
TDH3
Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall
YGR254W 2.96
ENO1
Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose
YJL158C 2.95
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
YNL028W 2.83 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YJL048C 2.76
UBX6
UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, transcription is repressed when cells are grown in media containing inositol and choline
YJR073C 2.74
OPI3
Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis
YGR139W 2.70 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YFL015W-A 2.69 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YFL015C 2.68 Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene
YBR092C 2.61
PHO3
Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin
YHR094C 2.55
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YER067W 2.54 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YER067W is not an essential gene
YDR044W 2.54
HEM13
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
YDR095C 2.51 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YLR258W 2.49
GSY2
Glycogen synthase, similar to Gsy1p; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase
YGR052W 2.47
FMP48
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation
YGL253W 2.45
HXK2
Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene
YPR119W 2.44
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YDL205C 2.41
HEM3
Phorphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p
YER066W 2.32 Putative protein of unknown function; YER066W is not an essential gene
YNR014W 2.26 Putative protein of unknown function; expression is cell-cycle regulated, Azf1p-dependent, and heat-inducible
YMR290C 2.24
HAS1
ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles
YDR345C 2.23
HXT3
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
YDR033W 2.18
MRH1
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p
YFR015C 2.18
GSY1
Glycogen synthase with similarity to Gsy2p, the more highly expressed yeast homolog; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase
YKL091C 2.14 Putative homolog of Sec14p, which is a phosphatidylinositol/phosphatidylcholine transfer protein involved in lipid metabolism; localizes to the nucleus
YIL111W 2.14
COX5B
Subunit Vb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during anaerobic growth while its isoform Va (Cox5Ap) is expressed during aerobic growth
YGR108W 2.11
CLB1
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YML103C 2.07
NUP188
Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex and of the nuclear envelope, also involved in nuclear envelope permeability, interacts with Pom152p and Nic96p
YOR273C 1.99
TPO4
Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily
YLR286C 1.97
CTS1
Endochitinase, required for cell separation after mitosis; transcriptional activation during late G and early M cell cycle phases is mediated by transcription factor Ace2p
YER124C 1.96
DSE1
Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall
YLR150W 1.96
STM1
Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations
YPR074C 1.96
TKL1
Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
YLR109W 1.94
AHP1
Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p
YNL178W 1.94
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YMR290W-A 1.93 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YJL153C 1.91
INO1
Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
YER131W 1.85
RPS26B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
YMR261C 1.84
TPS3
Regulatory subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway
YNL300W 1.83 Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid
YDR517W 1.83
GRH1
Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes
YLR177W 1.81 Putative protein of unknown function; phosphorylated by Dbf2p-Mob1p in vitro; some strains contain microsatellite polymophisms at this locus; YLR177W is not an essential gene
YDL055C 1.80
PSA1
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure
YPL037C 1.75
EGD1
Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b
YGR234W 1.75
YHB1
Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses
YPR157W 1.73 Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation
YGR086C 1.73
PIL1
Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria
YJR094W-A 1.71
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YBR206W 1.70 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene KTR3
YGL202W 1.69
ARO8
Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis
YHR180W-A 1.67 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious ORF YHR180C-B and long terminal repeat YHRCsigma3
YML052W 1.65
SUR7
Putative integral membrane protein; component of eisosomes; associated with endocytosis, along with Pil1p and Lsp1p; sporulation and plasma membrane sphingolipid content are altered in mutants
YDL023C 1.63 Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance
YBR158W 1.63
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YKL008C 1.63
LAC1
Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p
YOL101C 1.61
IZH4
Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism
YJL196C 1.58
ELO1
Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids
YEL001C 1.57
IRC22
Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci
YPR149W 1.56
NCE102
Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs)
YMR266W 1.55
RSN1
Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant
YHR181W 1.55
SVP26
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment
YLR154C 1.53
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YNL066W 1.53
SUN4
Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family
YPR196W 1.52 Putative maltose activator
YMR297W 1.52
PRC1
Vacuolar carboxypeptidase Y (proteinase C), broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family
YER001W 1.49
MNN1
Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family
YER088C-A 1.49 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YMR082C 1.48 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGL012W 1.48
ERG4
C-24(28) sterol reductase, catalyzes the final step in ergosterol biosynthesis; mutants are viable, but lack ergosterol
YLR257W 1.47 Putative protein of unknown function
YCR009C 1.42
RVS161
Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress
YDR541C 1.42 Putative dihydrokaempferol 4-reductase
YJR103W 1.42
URA8
Minor CTP synthase isozyme (see also URA7), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis
YDL022W 1.42
GPD1
NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
YMR262W 1.41 Protein of unknown function; interacts weakly with Knr4p; YMR262W is not an essential gene
YOR317W 1.40
FAA1
Long chain fatty acyl-CoA synthetase with a preference for C12:0-C16:0 fatty acids; involved in the activation of imported fatty acids; localized to both lipid particles and mitochondrial outer membrane; essential for stationary phase
YEL056W 1.40
HAT2
Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing
YHR163W 1.37
SOL3
6-phosphogluconolactonase, catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p
YDR185C 1.37 Mitochondrial protein of unknown function; has similarity to Ups1p, which is involved in regulation of alternative topogenesis of the dynamin-related GTPase Mgm1p
YDR344C 1.37 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YAL033W 1.37
POP5
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
YJR074W 1.36
MOG1
Conserved nuclear protein that interacts with GTP-Gsp1p, which is a Ran homolog of the Ras GTPase family, and stimulates nucleotide release, involved in nuclear protein import, nucleotide release is inhibited by Yrb1p
YPL247C 1.35 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; similar to the petunia WD repeat protein an11; YPL247C is not an essential gene
YGR279C 1.34
SCW4
Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating
YNL029C 1.34
KTR5
Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
YBL044W 1.34 Putative protein of unknown function; YBL044W is not an essential protein
YKL182W 1.33
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YER130C 1.33 Hypothetical protein
YKL090W 1.29
CUE2
Protein of unknown function; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination
YOR226C 1.26
ISU2
Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable
YDR309C 1.23
GIC2
Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region
YGL148W 1.23
ARO2
Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids
YIL051C 1.21
MMF1
Mitochondrial protein involved in maintenance of the mitochondrial genome
YHR162W 1.21 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion
YER083C 1.21
GET2
Subunit of the GET complex; required for meiotic nuclear division and for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion; may be involved in cell wall function
YGL199C 1.20 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YIP4/YGL198W
YHR010W 1.20
RPL27A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein
YBR085C-A 1.20 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus
YLR437C 1.19 Putative protein of unknown function; epitope tagged protein localizes to the cytoplasm
YDR276C 1.19
PMP3
Small plasma membrane protein related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature, not essential for viability, deletion causes hyperpolarization of the plasma membrane potential
YGL225W 1.19
VRG4
Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi
YJR113C 1.19
RSM7
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S7 ribosomal protein
YNL193W 1.18 Putative protein of unknown function; exhibits a two-hybrid interaction with Yhr151cp in a large-scale analysis
YPL263C 1.17
KEL3
Cytoplasmic protein of unknown function
YFR054C 1.17 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDR094W 1.16 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2
YLL050C 1.14
COF1
Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds both actin monomers and filaments and severs filaments; thought to be regulated by phosphorylation at SER4; ubiquitous and essential in eukaryotes
YJR102C 1.14
VPS25
Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome
YPL274W 1.14
SAM3
High-affinity S-adenosylmethionine permease, required for utilization of S-adenosylmethionine as a sulfur source; has similarity to S-methylmethionine permease Mmp1p
YDL022C-A 1.14 Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene DIA3; identified by fungal homology and RT-PCR
YMR205C 1.13
PFK2
Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
YKL128C 1.13
PMU1
Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant
YHL028W 1.13
WSC4
ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3
YGR127W 1.13 Putative protein of unknown function; expression is regulated by Msn2p/Msn4p, indicating a possible role in stress response
YKR074W 1.12
AIM29
Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
YHR190W 1.12
ERG9
Farnesyl-diphosphate farnesyl transferase (squalene synthase), joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway
YPL087W 1.10
YDC1
Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroceramide to a free fatty acid and dihydrosphingosine; has a minor reverse activity
YLR154W-B 1.10 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YEL073C 1.10 Putative protein of unknown function; located adjacent to ARS503 and the telomere on the left arm of chromosome V; regulated by inositol/choline
YDR279W 1.08
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YBR177C 1.08
EHT1
Acyl-coenzymeA:ethanol O-acyltransferase that plays a minor role in medium-chain fatty acid ethyl ester biosynthesis; possesses short-chain esterase activity; localizes to lipid particles and the mitochondrial outer membrane
YDR074W 1.07
TPS2
Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway
YER177W 1.07
BMH1
14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling
YOL155C 1.06
HPF1
Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines
YGR242W 1.05 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C
YGR107W 1.04 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YGR241C 1.03
YAP1802
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family
YEL038W 1.03
UTR4
Protein of unknown function with sequence similarity to 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatases, found in both the cytoplasm and nucleus
YDL125C 1.02
HNT1
Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint
YPR063C 1.02 ER-localized protein of unknown function
YAL038W 1.02
CDC19
Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
YHR141C 1.00
RPL42B
Protein component of the large (60S) ribosomal subunit, identical to Rpl42Ap and has similarity to rat L44; required for propagation of the killer toxin-encoding M1 double-stranded RNA satellite of the L-A double-stranded RNA virus
YMR246W 1.00
FAA4
Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids
YGR020C 1.00
VMA7
Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane
YGR050C 0.99 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YGL037C 0.98
PNC1
Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span
YJL007C 0.98 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YNR013C 0.98
PHO91
Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YLR312W-A 0.97
MRPL15
Mitochondrial ribosomal protein of the large subunit
YJR114W 0.97 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RSM7/YJR113C
YFL022C 0.96
FRS2
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YKR066C 0.95
CCP1
Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress
YML004C 0.95
GLO1
Monomeric glyoxalase I, catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress
YDR245W 0.94
MNN10
Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family
YOR013W 0.94
IRC11
Dubious opening reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YOR012C; null mutant displays increased levels of spontaneous Rad52 foci
YNL030W 0.93
HHF2
One of two identical histone H4 proteins (see also HHF1); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity
YDR002W 0.93
YRB1
Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1
YOR320C 0.93
GNT1
N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus
YGR131W 0.93 Protein of unknown function; expression induced in response to ketoconazole; promoter region contains a sterol regulatory element motif, which has been identified as a Upc2p-binding site
YDR385W 0.93
EFT2
Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
YHR025W 0.90
THR1
Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by the GCN4-mediated general amino acid control pathway
YPR148C 0.90 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YER182W 0.90
FMP10
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YNL301C 0.90
RPL18B
Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein
YML102W 0.90
CAC2
Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans
YLR012C 0.89 Putative protein of unknown function; YLR012C is not an essential gene
YLR029C 0.89
RPL15A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Bp and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
YLR206W 0.89
ENT2
Epsin-like protein required for endocytosis and actin patch assembly and functionally redundant with Ent1p; contains clathrin-binding motif at C-terminus
YDR381W 0.89
YRA1
Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function
YGL040C 0.88
HEM2
Delta-aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen, the second step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus
YMR194C-A 0.87 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YER019C-A 0.87
SBH2
Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p
YGR264C 0.86
MES1
Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs
YMR083W 0.86
ADH3
Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production
YOL030W 0.85
GAS5
1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
YOR376W-A 0.84 Putative protein of unknown function; identified by fungal homology and RT-PCR
YOR047C 0.83
STD1
Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p
YGL082W 0.82 Putative protein of unknown function; predicted prenylation/proteolysis target of Afc1p and Rce1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YGL082W is not an essential gene
YAL029C 0.82
MYO4
One of two type V myosin motors (along with MYO2) involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p
YCR031C 0.81
RPS14A
Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins
YKL127W 0.80
PGM1
Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism
YPL015C 0.79
HST2
Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro
YGR266W 0.78 Protein of unknown function, predicted to contain a single transmembrane domain; localized to both the mitochondrial outer membrane and the plasma membrane
YJR009C 0.78
TDH2
Glyceraldehyde-3-phosphate dehydrogenase, isozyme 2, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall
YDL101C 0.78
DUN1
Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair
YOR293W 0.77
RPS10A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Bp and has similarity to rat ribosomal protein S10

Network of associatons between targets according to the STRING database.

First level regulatory network of REI1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
1.7 5.0 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
1.5 6.2 GO:0000296 spermine transport(GO:0000296)
1.3 9.2 GO:0009312 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
1.3 5.1 GO:0046513 ceramide metabolic process(GO:0006672) ceramide biosynthetic process(GO:0046513)
0.9 6.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.7 5.1 GO:0019655 glucose catabolic process(GO:0006007) glycolytic fermentation to ethanol(GO:0019655) glycolytic fermentation(GO:0019660) hexose catabolic process to ethanol(GO:1902707)
0.7 2.0 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.7 4.6 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
0.6 2.4 GO:0035337 long-chain fatty acid transport(GO:0015909) fatty-acyl-CoA metabolic process(GO:0035337)
0.6 1.8 GO:0060548 negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069) negative regulation of cell death(GO:0060548)
0.6 1.1 GO:0015848 spermidine transport(GO:0015848)
0.6 1.7 GO:1902223 tyrosine biosynthetic process(GO:0006571) L-phenylalanine biosynthetic process(GO:0009094) erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process(GO:1902223)
0.6 2.2 GO:0046323 mannose metabolic process(GO:0006013) glucose import(GO:0046323)
0.5 4.2 GO:0005987 sucrose metabolic process(GO:0005985) sucrose catabolic process(GO:0005987)
0.5 2.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.5 2.9 GO:0070941 eisosome assembly(GO:0070941)
0.5 1.4 GO:0065005 lipid tube assembly(GO:0060988) protein-lipid complex assembly(GO:0065005) protein-lipid complex subunit organization(GO:0071825)
0.5 11.8 GO:0006757 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.5 1.8 GO:0030497 fatty acid elongation(GO:0030497)
0.4 1.8 GO:0014070 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
0.4 1.3 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.4 1.7 GO:0019748 secondary metabolic process(GO:0019748)
0.4 2.4 GO:0006491 N-glycan processing(GO:0006491)
0.4 2.0 GO:1901072 aminoglycan catabolic process(GO:0006026) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.4 1.9 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4 1.9 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.4 2.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.4 1.9 GO:0006021 inositol biosynthetic process(GO:0006021)
0.4 2.1 GO:0007030 Golgi organization(GO:0007030)
0.3 1.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.3 2.0 GO:0006116 NADH oxidation(GO:0006116)
0.3 5.9 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.3 1.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3 0.9 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.3 1.2 GO:0046417 chorismate biosynthetic process(GO:0009423) chorismate metabolic process(GO:0046417)
0.3 1.4 GO:0009208 CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036)
0.3 0.8 GO:0070637 nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637)
0.3 0.8 GO:0006531 aspartate metabolic process(GO:0006531)
0.3 1.6 GO:0030042 actin filament depolymerization(GO:0030042)
0.3 1.8 GO:0010969 regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion(GO:0010969) regulation of signal transduction involved in conjugation with cellular fusion(GO:0060238)
0.3 0.8 GO:0009438 methylglyoxal metabolic process(GO:0009438) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.3 3.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 2.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.7 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.2 1.2 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.2 0.5 GO:0043097 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.2 1.0 GO:0019357 nicotinate nucleotide biosynthetic process(GO:0019357) nicotinate nucleotide salvage(GO:0019358) pyridine nucleotide salvage(GO:0019365) nicotinate nucleotide metabolic process(GO:0046497)
0.2 0.6 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.2 1.7 GO:0006563 L-serine metabolic process(GO:0006563)
0.2 2.3 GO:0006549 isoleucine metabolic process(GO:0006549)
0.2 1.0 GO:0006829 zinc II ion transport(GO:0006829)
0.2 1.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.2 3.0 GO:0006999 nuclear pore organization(GO:0006999)
0.2 0.9 GO:0045338 terpenoid metabolic process(GO:0006721) terpenoid biosynthetic process(GO:0016114) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
0.2 1.7 GO:0008299 isoprenoid metabolic process(GO:0006720) isoprenoid biosynthetic process(GO:0008299)
0.2 0.4 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
0.2 1.8 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.2 1.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 4.4 GO:0006885 regulation of pH(GO:0006885)
0.2 1.8 GO:0000917 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529)
0.2 1.4 GO:0006797 polyphosphate metabolic process(GO:0006797)
0.2 0.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 0.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.2 3.6 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.2 0.5 GO:0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674)
0.1 1.3 GO:0034965 intronic snoRNA processing(GO:0031070) intronic box C/D snoRNA processing(GO:0034965)
0.1 0.4 GO:0033241 regulation of cellular amine catabolic process(GO:0033241)
0.1 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 1.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 1.0 GO:0048309 endoplasmic reticulum inheritance(GO:0048309)
0.1 0.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.9 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 0.5 GO:0098610 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.1 0.3 GO:0016320 endoplasmic reticulum membrane fusion(GO:0016320)
0.1 0.6 GO:1901070 GMP biosynthetic process(GO:0006177) guanosine-containing compound biosynthetic process(GO:1901070)
0.1 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.7 GO:0051031 tRNA transport(GO:0051031)
0.1 1.2 GO:0009636 response to toxic substance(GO:0009636)
0.1 1.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.6 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.1 0.2 GO:0008216 spermidine metabolic process(GO:0008216)
0.1 0.9 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 0.4 GO:0007009 plasma membrane organization(GO:0007009)
0.1 1.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.3 GO:0010922 positive regulation of phosphatase activity(GO:0010922)
0.1 0.3 GO:0031684 heterotrimeric G-protein complex cycle(GO:0031684)
0.1 0.4 GO:1900434 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
0.1 1.7 GO:0044108 ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
0.1 0.3 GO:0018216 peptidyl-arginine modification(GO:0018195) peptidyl-arginine methylation(GO:0018216)
0.1 0.2 GO:0072369 regulation of lipid transport(GO:0032368) positive regulation of lipid transport(GO:0032370) regulation of sterol transport(GO:0032371) positive regulation of sterol transport(GO:0032373) positive regulation of transmembrane transport(GO:0034764) regulation of sterol import by regulation of transcription from RNA polymerase II promoter(GO:0035968) positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter(GO:0035969) regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) regulation of sterol import(GO:2000909) positive regulation of sterol import(GO:2000911)
0.1 1.2 GO:0007120 axial cellular bud site selection(GO:0007120)
0.1 0.5 GO:0070096 mitochondrial outer membrane translocase complex assembly(GO:0070096)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.7 GO:0018410 C-terminal protein amino acid modification(GO:0018410) post-translational protein modification(GO:0043687)
0.1 2.6 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.3 GO:0034473 U1 snRNA 3'-end processing(GO:0034473)
0.1 0.2 GO:0006734 NADH metabolic process(GO:0006734)
0.1 2.5 GO:0045047 protein targeting to ER(GO:0045047)
0.1 0.2 GO:0015908 fatty acid transport(GO:0015908)
0.1 0.3 GO:0006598 polyamine catabolic process(GO:0006598)
0.1 0.3 GO:0034354 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627)
0.1 0.2 GO:0046083 adenine metabolic process(GO:0046083)
0.1 9.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.2 GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.1 0.3 GO:0044070 regulation of anion transport(GO:0044070)
0.1 0.2 GO:0051469 vesicle fusion with vacuole(GO:0051469)
0.1 0.5 GO:0001009 transcription from RNA polymerase III type 2 promoter(GO:0001009) transcription from a RNA polymerase III hybrid type promoter(GO:0001041)
0.1 0.4 GO:0097502 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.1 0.2 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.6 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.2 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 2.0 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.6 GO:0006857 oligopeptide transport(GO:0006857)
0.1 1.2 GO:0042797 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.5 GO:0051278 fungal-type cell wall chitin biosynthetic process(GO:0034221) fungal-type cell wall polysaccharide biosynthetic process(GO:0051278) fungal-type cell wall polysaccharide metabolic process(GO:0071966)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.4 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.1 0.7 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.1 0.3 GO:0045116 protein neddylation(GO:0045116)
0.1 0.5 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 0.1 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.4 GO:0000372 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.1 0.2 GO:1900542 regulation of purine nucleotide metabolic process(GO:1900542)
0.1 0.7 GO:0006826 iron ion transport(GO:0006826)
0.1 1.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.1 GO:0009409 response to cold(GO:0009409) cellular response to cold(GO:0070417)
0.1 1.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0032365 intracellular lipid transport(GO:0032365)
0.0 0.1 GO:0009411 response to UV(GO:0009411)
0.0 1.6 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593)
0.0 0.0 GO:0032956 regulation of actin cytoskeleton organization(GO:0032956) regulation of actin filament-based process(GO:0032970)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.2 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0007535 donor selection(GO:0007535)
0.0 0.7 GO:0042723 thiamine-containing compound metabolic process(GO:0042723)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.5 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.6 GO:0001100 negative regulation of exit from mitosis(GO:0001100)
0.0 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.3 GO:1901661 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.3 GO:0032120 ascospore-type prospore membrane assembly(GO:0032120) membrane biogenesis(GO:0044091) membrane assembly(GO:0071709)
0.0 0.1 GO:0036257 multivesicular body organization(GO:0036257)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0000743 nuclear migration involved in conjugation with cellular fusion(GO:0000743)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0043173 purine nucleotide salvage(GO:0032261) purine-containing compound salvage(GO:0043101) nucleotide salvage(GO:0043173)
0.0 0.1 GO:0030541 plasmid partitioning(GO:0030541)
0.0 0.6 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.4 GO:0007121 bipolar cellular bud site selection(GO:0007121)
0.0 0.1 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.1 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0040001 establishment of mitotic spindle orientation(GO:0000132) establishment of mitotic spindle localization(GO:0040001) establishment of spindle orientation(GO:0051294)
0.0 2.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:0015940 pantothenate metabolic process(GO:0015939) pantothenate biosynthetic process(GO:0015940)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.1 GO:0010695 regulation of spindle pole body separation(GO:0010695)
0.0 0.2 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 1.1 GO:0007015 actin filament organization(GO:0007015)
0.0 0.1 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.3 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0000084 mitotic S phase(GO:0000084) S phase(GO:0051320)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.0 0.1 GO:0000161 MAPK cascade involved in osmosensory signaling pathway(GO:0000161)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0051598 meiotic cell cycle checkpoint(GO:0033313) meiotic recombination checkpoint(GO:0051598)
0.0 2.4 GO:0006364 rRNA processing(GO:0006364)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0046839 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0035753 maintenance of DNA trinucleotide repeats(GO:0035753)
0.0 0.0 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.0 1.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.0 GO:0048024 regulation of RNA splicing(GO:0043484) regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.0 GO:0034762 regulation of transmembrane transport(GO:0034762)
0.0 0.0 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0 0.0 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.0 0.1 GO:0072668 obsolete tubulin complex biogenesis(GO:0072668)
0.0 0.1 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.0 GO:0042743 hydrogen peroxide metabolic process(GO:0042743) hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.0 GO:0009090 homoserine biosynthetic process(GO:0009090)
0.0 0.2 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0000105 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020) microtubule polymerization(GO:0046785)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.6 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.9 2.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.6 1.9 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.5 2.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.5 1.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 1.3 GO:0043529 GET complex(GO:0043529)
0.4 2.4 GO:0032126 eisosome(GO:0032126)
0.4 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.4 1.1 GO:0000814 ESCRT II complex(GO:0000814)
0.3 1.4 GO:0030287 cell wall-bounded periplasmic space(GO:0030287)
0.3 1.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 2.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.3 0.9 GO:0033186 CAF-1 complex(GO:0033186)
0.3 22.3 GO:0005576 extracellular region(GO:0005576)
0.3 0.9 GO:0071261 Ssh1 translocon complex(GO:0071261)
0.3 0.9 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.3 0.8 GO:0070545 PeBoW complex(GO:0070545)
0.3 3.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.3 1.8 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 6.5 GO:0009277 fungal-type cell wall(GO:0009277)
0.2 2.1 GO:0000328 fungal-type vacuole lumen(GO:0000328)
0.2 0.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 1.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.2 1.7 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.2 2.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 2.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 1.1 GO:0005884 actin filament(GO:0005884)
0.2 0.5 GO:0000930 gamma-tubulin small complex, spindle pole body(GO:0000928) gamma-tubulin complex(GO:0000930) gamma-tubulin small complex(GO:0008275)
0.2 0.9 GO:0000136 alpha-1,6-mannosyltransferase complex(GO:0000136)
0.2 0.6 GO:0000938 GARP complex(GO:0000938)
0.2 0.9 GO:0035339 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
0.1 1.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681)
0.1 11.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.5 GO:0032432 actin filament bundle(GO:0032432)
0.1 0.9 GO:0000346 transcription export complex(GO:0000346)
0.1 2.0 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 7.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.5 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.4 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.1 1.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.8 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.3 GO:0046930 pore complex(GO:0046930)
0.1 0.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 2.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 3.4 GO:0005811 lipid particle(GO:0005811)
0.1 1.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 8.8 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.4 GO:0030478 actin cap(GO:0030478)
0.1 3.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.3 GO:0044697 HICS complex(GO:0044697)
0.1 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.8 GO:0030118 clathrin coat(GO:0030118)
0.1 1.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.2 GO:0005827 polar microtubule(GO:0005827) tubulin complex(GO:0045298)
0.1 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.3 GO:0045254 mitochondrial pyruvate dehydrogenase complex(GO:0005967) pyruvate dehydrogenase complex(GO:0045254)
0.1 0.2 GO:0070860 RNA polymerase I core factor complex(GO:0070860)
0.1 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.5 GO:0035097 histone methyltransferase complex(GO:0035097) Set1C/COMPASS complex(GO:0048188)
0.1 1.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 11.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 0.4 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0033101 cellular bud membrane(GO:0033101)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 3.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0034456 UTP-C complex(GO:0034456)
0.0 0.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.7 GO:0005815 microtubule organizing center(GO:0005815) spindle pole body(GO:0005816)
0.0 0.1 GO:0033597 mitotic checkpoint complex(GO:0033597)
0.0 0.1 GO:0000148 1,3-beta-D-glucan synthase complex(GO:0000148)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 3.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.0 GO:0005840 ribosome(GO:0005840)
0.0 0.1 GO:0072380 ER membrane insertion complex(GO:0072379) TRC complex(GO:0072380)
0.0 0.1 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0036452 ESCRT complex(GO:0036452)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.7 GO:0030479 actin cortical patch(GO:0030479) endocytic patch(GO:0061645)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.0 GO:0030907 MBF transcription complex(GO:0030907) SBF transcription complex(GO:0033309)
0.0 0.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity(GO:0003825)
2.2 9.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.6 4.9 GO:0004564 beta-fructofuranosidase activity(GO:0004564) sucrose alpha-glucosidase activity(GO:0004575)
1.5 6.2 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
1.5 9.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.4 5.8 GO:0004396 hexokinase activity(GO:0004396)
1.3 3.8 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.1 6.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
1.1 1.1 GO:0004805 trehalose-phosphatase activity(GO:0004805)
1.0 3.9 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.7 2.7 GO:0015146 pentose transmembrane transporter activity(GO:0015146)
0.7 2.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.6 1.9 GO:0016872 intramolecular lyase activity(GO:0016872)
0.6 2.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.6 2.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.6 3.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.6 1.8 GO:0009922 fatty acid elongase activity(GO:0009922)
0.6 1.8 GO:0070568 guanylyltransferase activity(GO:0070568)
0.6 1.1 GO:0015606 spermidine transmembrane transporter activity(GO:0015606)
0.5 6.6 GO:0005199 structural constituent of cell wall(GO:0005199)
0.5 4.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.5 1.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 1.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.4 2.0 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.4 1.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.4 1.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 1.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.4 1.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.3 2.1 GO:0016408 C-acyltransferase activity(GO:0016408)
0.3 3.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.3 1.0 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.3 1.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.3 1.9 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.3 1.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 1.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 0.9 GO:0019202 amino acid kinase activity(GO:0019202)
0.3 1.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 1.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.3 0.9 GO:0019003 GDP binding(GO:0019003)
0.3 2.6 GO:0005216 ion channel activity(GO:0005216)
0.3 1.3 GO:0004026 alcohol O-acetyltransferase activity(GO:0004026) alcohol O-acyltransferase activity(GO:0034318)
0.2 1.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.2 1.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 1.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 1.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 0.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 2.8 GO:0051015 actin filament binding(GO:0051015)
0.2 1.2 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.2 0.7 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.2 1.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2 1.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.2 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.2 1.1 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.2 1.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 1.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.9 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 1.8 GO:0030276 clathrin binding(GO:0030276)
0.1 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 2.8 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.8 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 2.4 GO:0015926 glucosidase activity(GO:0015926)
0.1 1.4 GO:0043495 protein anchor(GO:0043495)
0.1 1.3 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.8 GO:0042124 glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124)
0.1 0.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 3.0 GO:0019901 protein kinase binding(GO:0019901)
0.1 0.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 3.7 GO:0008237 metallopeptidase activity(GO:0008237)
0.1 3.1 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 0.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.7 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 1.0 GO:0010181 FMN binding(GO:0010181)
0.1 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.7 GO:0051287 NAD binding(GO:0051287)
0.1 0.9 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.1 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0008137 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 1.0 GO:0008194 UDP-glycosyltransferase activity(GO:0008194)
0.1 20.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.7 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.1 2.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.6 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 0.2 GO:0016972 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) thiol oxidase activity(GO:0016972)
0.1 1.4 GO:0019843 rRNA binding(GO:0019843)
0.1 0.3 GO:0016725 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0015188 L-tyrosine transmembrane transporter activity(GO:0005302) L-glutamine transmembrane transporter activity(GO:0015186) L-isoleucine transmembrane transporter activity(GO:0015188) branched-chain amino acid transmembrane transporter activity(GO:0015658)
0.1 1.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 2.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.1 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 1.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.6 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.2 GO:0016615 malate dehydrogenase activity(GO:0016615) L-malate dehydrogenase activity(GO:0030060)
0.1 1.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 0.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.5 GO:0019239 deaminase activity(GO:0019239)
0.1 0.5 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 0.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.2 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.1 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0015151 alpha-glucoside transmembrane transporter activity(GO:0015151) glucoside transmembrane transporter activity(GO:0042947)
0.0 2.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0043812 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0019201 nucleotide kinase activity(GO:0019201)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.0 1.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0004619 phosphoglycerate mutase activity(GO:0004619)
0.0 1.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:1901474 azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0035591 MAP-kinase scaffold activity(GO:0005078) signaling adaptor activity(GO:0035591)
0.0 0.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.2 GO:0099516 ion antiporter activity(GO:0099516)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.0 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.3 GO:0008092 cytoskeletal protein binding(GO:0008092)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.7 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0008144 drug binding(GO:0008144)
0.0 0.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.0 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.2 0.6 PID SHP2 PATHWAY SHP2 signaling
0.1 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 36.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.0 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.7 2.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.7 2.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.4 1.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.3 2.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.2 3.8 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.2 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 0.6 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
0.1 0.4 REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM Genes involved in Cytokine Signaling in Immune system
0.1 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.2 REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES Genes involved in Transmembrane transport of small molecules
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 38.5 REACTOME GLYCOSAMINOGLYCAN METABOLISM Genes involved in Glycosaminoglycan metabolism
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME REGULATION OF MITOTIC CELL CYCLE Genes involved in Regulation of mitotic cell cycle
0.0 0.3 REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS Genes involved in Metabolism of lipids and lipoproteins
0.0 0.0 REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT Genes involved in The citric acid (TCA) cycle and respiratory electron transport