Results for RIM101
Z-value: 2.50
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Transcription factors associated with RIM101
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RIM101
|
S000001019 | Cys2His2 zinc-finger transcriptional repressor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YAL062W Show fit | 47.04 |
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources |
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| YJR095W Show fit | 31.15 |
Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization |
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| YDR536W Show fit | 30.71 |
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock |
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| YKL163W Show fit | 24.44 |
O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway |
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| YKL217W Show fit | 22.60 |
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose |
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| YOR383C Show fit | 22.47 |
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
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| YOR382W Show fit | 21.03 |
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
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| YMR244W Show fit | 20.26 |
Putative protein of unknown function |
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| YMR017W Show fit | 16.47 |
Meiosis-specific subunit of the t-SNARE complex, required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; SNAP-25 homolog |
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| YAL063C Show fit | 14.82 |
Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation |
Network of associatons between targets according to the STRING database.
First level regulatory network of RIM101
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.1 | 48.5 | GO:0015891 | siderophore transport(GO:0015891) |
| 15.4 | 46.2 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
| 2.2 | 43.8 | GO:0008645 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
| 10.4 | 31.2 | GO:0015740 | C4-dicarboxylate transport(GO:0015740) |
| 5.9 | 29.3 | GO:0015793 | glycerol transport(GO:0015793) |
| 5.7 | 22.6 | GO:0006848 | pyruvate transport(GO:0006848) |
| 3.4 | 20.5 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 1.3 | 19.5 | GO:0031321 | ascospore-type prospore assembly(GO:0031321) |
| 2.0 | 18.2 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
| 5.9 | 17.8 | GO:0015888 | thiamine transport(GO:0015888) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 83.3 | GO:0005886 | plasma membrane(GO:0005886) |
| 0.1 | 53.0 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.3 | 44.5 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.7 | 33.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.2 | 24.1 | GO:0000324 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 0.9 | 20.4 | GO:0005628 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
| 1.1 | 18.0 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 4.4 | 13.2 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 1.5 | 12.0 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.5 | 11.7 | GO:0070469 | respiratory chain(GO:0070469) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 13.0 | 64.8 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 11.5 | 46.2 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 7.8 | 31.2 | GO:0015556 | C4-dicarboxylate transmembrane transporter activity(GO:0015556) |
| 0.6 | 26.0 | GO:0001228 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 2.2 | 22.3 | GO:0015205 | nucleobase transmembrane transporter activity(GO:0015205) |
| 0.6 | 19.2 | GO:0008234 | cysteine-type peptidase activity(GO:0008234) |
| 1.2 | 18.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 4.5 | 18.0 | GO:0005537 | mannose binding(GO:0005537) |
| 0.6 | 15.0 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 1.6 | 14.5 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 304.7 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 2.7 | 10.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 1.4 | 7.0 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.9 | 6.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 1.4 | 4.3 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 1.1 | 3.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.9 | 2.6 | PID FOXO PATHWAY | FoxO family signaling |
| 2.3 | 2.3 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.7 | 2.2 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.4 | 0.7 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 304.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 2.4 | 7.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.7 | 6.4 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 3.0 | 6.0 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.4 | 3.9 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.9 | 3.7 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 1.0 | 2.9 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 1.4 | 2.7 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.3 | 2.4 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.2 | 1.2 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |