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Results for STB1

Z-value: 0.82

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Transcription factors associated with STB1

Gene Symbol Gene ID Gene Info
STB1
S000005253 Protein involved in regulating MBF-specific transcription at Start

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STB1YNL309W-0.174.1e-01Click!

Activity profile of STB1 motif

Sorted Z-values of STB1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YFR055W 10.61
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YFR056C 9.41 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YNL301C 8.21
RPL18B
Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein
YKL096W-A 7.74
CWP2
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored
YNL030W 6.76
HHF2
One of two identical histone H4 proteins (see also HHF1); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity
YNL289W 6.31
PCL1
Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth
YGR108W 5.69
CLB1
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YDL055C 5.26
PSA1
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure
YGL097W 5.02
SRM1
Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p
YNL300W 4.33 Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid
YDL211C 4.27 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
YPL256C 3.86
CLN2
G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
YHL015W 3.85
RPS20
Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; has similarity to E. coli S10 and rat S20 ribosomal proteins
YGL179C 3.82
TOS3
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
YDR044W 3.68
HEM13
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
YNL031C 3.60
HHT2
One of two identical histone H3 proteins (see also HHT1); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation
YGL147C 3.49
RPL9A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins
YEL040W 3.34
UTR2
Cell wall protein that functions in the transfer of chitin to beta(1-6)glucan; putative chitin transglycosidase; glycosylphosphatidylinositol (GPI)-anchored protein localized to the bud neck; has a role in cell wall maintenance
YGR148C 3.29
RPL24B
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YOR226C 3.15
ISU2
Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable
YKR013W 2.89
PRY2
Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins
YBR210W 2.82
ERV15
Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p
YOR376W-A 2.81 Putative protein of unknown function; identified by fungal homology and RT-PCR
YGL039W 2.79 Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)
YIL009W 2.70
FAA3
Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YIR021W 2.61
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YDL003W 2.58
MCD1
Essential protein required for sister chromatid cohesion in mitosis and meiosis; subunit of the cohesin complex; expression is cell cycle regulated and peaks in S phase
YHR010W 2.50
RPL27A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein
YJR145C 2.41
RPS4A
Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
YLR333C 2.40
RPS25B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein
YML088W 2.40
UFO1
F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation
YBR088C 2.36
POL30
Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair
YOR375C 2.35
GDH1
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources
YOR342C 2.30 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus
YKR012C 2.28 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene PRY2
YPL163C 2.21
SVS1
Cell wall and vacuolar protein, required for wild-type resistance to vanadate
YMR307W 2.17
GAS1
Beta-1,3-glucanosyltransferase, required for cell wall assembly; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor
YOL086C 2.16
ADH1
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
YLR110C 2.14
CCW12
Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor
YGL225W 2.13
VRG4
Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi
YFL045C 2.11
SEC53
Phosphomannomutase, involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen
YPR157W 2.08 Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation
YJR043C 2.07
POL32
Third subunit of DNA polymerase delta, involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; interacts with Hys2p, PCNA (Pol30p), and Pol1p
YBL085W 2.06
BOI1
Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
YDR385W 2.06
EFT2
Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
YDR345C 2.05
HXT3
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
YIL009C-A 2.04
EST3
Component of the telomerase holoenzyme, involved in telomere replication
YLR437C 2.03 Putative protein of unknown function; epitope tagged protein localizes to the cytoplasm
YKL218C 2.02
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YNL231C 1.98
PDR16
Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p, localizes to lipid particles and microsomes, controls levels of various lipids, may regulate lipid synthesis, homologous to Pdr17p
YMR049C 1.95
ERB1
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
YGR138C 1.92
TPO2
Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily
YLR180W 1.92
SAM1
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)
YLR183C 1.90
TOS4
Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF
YHR144C 1.90
DCD1
Deoxycytidine monophosphate (dCMP) deaminase required for dCTP and dTTP synthesis; expression is NOT cell cycle regulated
YDR002W 1.89
YRB1
Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1
YGL040C 1.87
HEM2
Delta-aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen, the second step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus
YER156C 1.85 Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YLR185W 1.84
RPL37A
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein
YFR054C 1.84 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YBR106W 1.83
PHO88
Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations
YLR432W 1.82
IMD3
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed
YCR034W 1.81
FEN1
Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway
YEL053W-A 1.80 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YEL054C
YFL015C 1.78 Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene
YDR382W 1.78
RPP2B
Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
YER049W 1.77
TPA1
Protein of unknown function; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; has a role in translation termination efficiency, mRNA poly(A) tail length and mRNA stability
YKR092C 1.76
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YCL024W 1.74
KCC4
Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p
YBL003C 1.73
HTA2
One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
YIL169C 1.73 Putative protein of unknown function; serine/threonine rich and highly similar to YOL155C, a putative glucan alpha-1,4-glucosidase; transcript is induced in both high and low pH environments; YIL169C is a non-essential gene
YDR224C 1.73
HTB1
One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
YJL107C 1.72 Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi
YOL007C 1.72
CSI2
Protein of unknown function; green fluorescent protein (GFP)- fusion protein localizes to the mother side of the bud neck and the vacuole; YOL007C is not an essential gene
YCR099C 1.71 Putative protein of unknown function
YDR098C 1.70
GRX3
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
YFL015W-A 1.69 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YKL081W 1.68
TEF4
Translation elongation factor EF-1 gamma
YLR257W 1.67 Putative protein of unknown function
YKL128C 1.66
PMU1
Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant
YOL124C 1.66
TRM11
Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain
YMR144W 1.63 Putative protein of unknown function; localized to the nucleus; YMR144W is not an essential gene
YGR140W 1.63
CBF2
Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
YLR411W 1.61
CTR3
High-affinity copper transporter of the plasma membrane, acts as a trimer; gene is disrupted by a Ty2 transposon insertion in many laboratory strains of S. cerevisiae
YKL097C 1.61 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species
YPR119W 1.60
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YDR023W 1.59
SES1
Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p
YGR159C 1.59
NSR1
Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis
YDL219W 1.59
DTD1
D-Tyr-tRNA(Tyr) deacylase, functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes
YDL201W 1.56
TRM8
Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA
YCL023C 1.53 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF KCC4
YKL164C 1.53
PIR1
O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle
YDR450W 1.52
RPS18A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Bp and has similarity to E. coli S13 and rat S18 ribosomal proteins
YDR399W 1.49
HPT1
Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
YPL267W 1.49
ACM1
Cell cycle regulated protein of unknown function; associated with Cdh1p and may supress the APC/C[Cdh1]-mediated proteolysis of mitotic cyclins
YPL227C 1.48
ALG5
UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum
YGR040W 1.48
KSS1
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
YLR406C 1.46
RPL31B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YDL192W 1.45
ARF1
ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p
YPR063C 1.44 ER-localized protein of unknown function
YBR244W 1.44
GPX2
Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress
YGR157W 1.44
CHO2
Phosphatidylethanolamine methyltransferase (PEMT), catalyzes the first step in the conversion of phosphatidylethanolamine to phosphatidylcholine during the methylation pathway of phosphatidylcholine biosynthesis
YGL031C 1.44
RPL24A
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YNL162W 1.43
RPL42A
Protein component of the large (60S) ribosomal subunit, identical to Rpl42Bp and has similarity to rat L44 ribosomal protein
YBR023C 1.42
CHS3
Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan
YMR083W 1.41
ADH3
Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production
YBL002W 1.41
HTB2
One of two nearly identical (see HTB1) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
YDL189W 1.40
RBS1
Protein of unknown function, identified as a high copy suppressor of psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization; proposed to bind single-stranded nucleic acids via its R3H domain
YMR121C 1.40
RPL15B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
YDR509W 1.39 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGR152C 1.39
RSR1
GTP-binding protein of the ras superfamily required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases
YPL081W 1.38
RPS9A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Bp and has similarity to E. coli S4 and rat S9 ribosomal proteins
YBR084C-A 1.38
RPL19A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Bp and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal
YDR508C 1.37
GNP1
High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids
YER001W 1.36
MNN1
Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family
YLL035W 1.36
GRC3
Protein of unknown function, required for cell growth and possibly involved in rRNA processing; mRNA is cell cycle regulated
YMR106C 1.36
YKU80
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
YDR225W 1.34
HTA1
One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
YBL031W 1.34
SHE1
Cytoskeletal protein of unknown function; overexpression causes growth arrest
YBR202W 1.32
MCM7
Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase
YMR241W 1.31
YHM2
Mitochondrial DNA-binding protein, component of the mitochondrial nucleoid structure, involved in mtDNA replication and segregation of mitochondrial genomes; member of the mitochondrial carrier protein family
YHR141C 1.31
RPL42B
Protein component of the large (60S) ribosomal subunit, identical to Rpl42Ap and has similarity to rat L44; required for propagation of the killer toxin-encoding M1 double-stranded RNA satellite of the L-A double-stranded RNA virus
YJL158C 1.30
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
YJL115W 1.30
ASF1
Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition
YEL068C 1.30 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YJL162C 1.29
JJJ2
Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein
YLR388W 1.28
RPS29A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Bp and has similarity to rat S29 and E. coli S14 ribosomal proteins
YDR064W 1.25
RPS13
Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins
YOL039W 1.25
RPP2A
Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
YBL009W 1.25
ALK2
Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk1p and to mammalian haspins
YMR305C 1.25
SCW10
Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p
YJL106W 1.24
IME2
Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p
YKL096W 1.23
CWP1
Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization
YGR090W 1.23
UTP22
Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
YGL030W 1.23
RPL30
Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript
YBR112C 1.23
CYC8
General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters
YJL080C 1.23
SCP160
Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins
YGR106C 1.22
VOA1
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar memebrane
YHR071C-A 1.22 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF ERG7/YHR072W
YER070W 1.22
RNR1
One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits
YMR296C 1.21
LCB1
Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine
YDR344C 1.21 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YHR216W 1.21
IMD2
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
YOL101C 1.21
IZH4
Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism
YLR109W 1.20
AHP1
Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p
YOR025W 1.19
HST3
Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
YEL001C 1.19
IRC22
Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci
YDR384C 1.18
ATO3
Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters
YHR149C 1.17
SKG6
Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p
YOL040C 1.17
RPS15
Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S19 and rat S15 ribosomal proteins
YDL136W 1.16
RPL35B
Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein
YER003C 1.16
PMI40
Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation
YJL212C 1.14
OPT1
Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family
YFL037W 1.14
TUB2
Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules
YGR187C 1.13
HGH1
Nonessential protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; similar to mammalian BRP16 (Brain protein 16)
YBR009C 1.13
HHF1
One of two identical histone H4 proteins (see also HHF2); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity
YOL123W 1.10
HRP1
Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences
YPR170W-B 1.10 Putative protein of unknown function, conserved in fungi; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C
YPL255W 1.08
BBP1
Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p
YIL118W 1.08
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YNR018W 1.07
AIM38
Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
YAR002W 1.07
NUP60
Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; potential Cdc28p substrate; involved in telomere maintenance
YMR208W 1.05
ERG12
Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
YJR143C 1.05
PMT4
Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; appears to form homodimers in vivo and does not complex with other Pmt proteins; target for new antifungals
YIL069C 1.04
RPS24B
Protein component of the small (40S) ribosomal subunit; identical to Rps24Ap and has similarity to rat S24 ribosomal protein
YPL265W 1.04
DIP5
Dicarboxylic amino acid permease, mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly
YMR125W 1.04
STO1
Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80
YKL068W-A 1.03 Putative protein of unknown function; identified by homology to Ashbya gossypii
YLR108C 1.02 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene
YCR018C 1.02
SRD1
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
YOR216C 1.02
RUD3
Golgi matrix protein involved in the structural organization of the cis-Golgi; interacts genetically with COG3 and USO1
YNR016C 1.02
ACC1
Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids
YGR139W 1.02 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDL084W 1.01
SUB2
Component of the TREX complex required for nuclear mRNA export; member of the DEAD-box RNA helicase superfamily and is involved in early and late steps of spliceosome assembly; homolog of the human splicing factor hUAP56
YCL018W 1.01
LEU2
Beta-isopropylmalate dehydrogenase (IMDH), catalyzes the third step in the leucine biosynthesis pathway
YGL201C 1.01
MCM6
Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
YMR108W 1.01
ILV2
Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control
YIL015W 1.00
BAR1
Aspartyl protease secreted into the periplasmic space of mating type a cells, helps cells find mating partners, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest
YCR006C 1.00 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YNL302C 1.00
RPS19B
Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Ap
YDR279W 0.99
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YKL127W 0.99
PGM1
Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism
YGL116W 0.98
CDC20
Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate
YOL005C 0.98
RPB11
RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit
YML036W 0.98
CGI121
Protein involved in telomere uncapping and elongation as component of the KEOPS protein complex with Bud32p, Kae1p, Pcc1p, and Gon7p; also shown to be a component of the EKC protein complex; homolog of human CGI-121
YDR324C 0.98
UTP4
Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
YPL055C 0.98
LGE1
Protein of unknown function; null mutant forms abnormally large cells, and homozygous diploid null mutant displays delayed premeiotic DNA synthesis and reduced efficiency of meiotic nuclear division
YOR094W 0.97
ARF3
Glucose-repressible ADP-ribosylation factor, GTPase of the Ras superfamily involved in development of polarity
YNL016W 0.96
PUB1
Poly(A)+ RNA-binding protein, abundant mRNP-component protein that binds mRNA and is required for stability of a number of mRNAs; not reported to associate with polyribosomes
YNR054C 0.96
ESF2
Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome
YKL156W 0.95
RPS27A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Bp and has similarity to rat S27 ribosomal protein
YPL254W 0.95
HFI1
Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions
YDR094W 0.95 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2
YDL019C 0.95
OSH2
Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability
YIL123W 0.93
SIM1
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated
YAL033W 0.93
POP5
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
YLR042C 0.92 Protein of unknown function; localizes to the cytoplasm; YLL042C is not an essential gene
YHR072W 0.91
ERG7
Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide, a step in ergosterol biosynthesis
YMR308C 0.91
PSE1
Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p
YDR047W 0.91
HEM12
Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; activity inhibited by Cu2+, Zn2+, Fe2+, Fe3+ and sulfhydryl-specific reagents

Network of associatons between targets according to the STRING database.

First level regulatory network of STB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
2.8 8.5 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
1.1 7.8 GO:0034729 histone H3-K79 methylation(GO:0034729)
1.1 7.6 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
0.9 6.5 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.9 4.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.9 4.4 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.9 2.6 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.8 2.5 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.8 4.0 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.8 4.0 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.8 2.3 GO:0009177 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.8 3.0 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
0.8 3.0 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.7 2.9 GO:0014070 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
0.7 2.1 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.6 2.6 GO:0000296 spermine transport(GO:0000296)
0.6 1.8 GO:2000877 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.5 2.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.5 9.8 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.5 2.2 GO:0030497 fatty acid elongation(GO:0030497)
0.5 2.1 GO:0000771 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.5 4.5 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.5 2.0 GO:0060188 regulation of protein desumoylation(GO:0060188)
0.5 2.4 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.5 1.4 GO:1900101 regulation of endoplasmic reticulum unfolded protein response(GO:1900101)
0.5 5.5 GO:0006272 leading strand elongation(GO:0006272)
0.5 5.9 GO:0006037 cell wall chitin metabolic process(GO:0006037)
0.5 1.8 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.4 0.4 GO:0033239 negative regulation of cellular amine metabolic process(GO:0033239)
0.4 1.3 GO:0043171 peptide catabolic process(GO:0043171)
0.4 1.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.4 5.0 GO:0007120 axial cellular bud site selection(GO:0007120)
0.4 2.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 1.2 GO:0048024 regulation of RNA splicing(GO:0043484) regulation of mRNA splicing, via spliceosome(GO:0048024)
0.4 6.5 GO:0006334 nucleosome assembly(GO:0006334)
0.4 1.6 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.4 2.4 GO:0051597 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.4 54.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.4 1.2 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.4 1.2 GO:0009094 L-phenylalanine biosynthetic process(GO:0009094) erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process(GO:1902223)
0.4 1.5 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.4 1.1 GO:0046677 response to antibiotic(GO:0046677)
0.4 1.1 GO:0097549 heterochromatin organization involved in chromatin silencing(GO:0070868) chromatin organization involved in negative regulation of transcription(GO:0097549)
0.4 1.5 GO:0007535 donor selection(GO:0007535)
0.4 0.7 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.4 1.4 GO:0051046 regulation of exocytosis(GO:0017157) regulation of secretion(GO:0051046) regulation of secretion by cell(GO:1903530)
0.3 0.7 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.3 0.7 GO:0031384 regulation of initiation of mating projection growth(GO:0031384)
0.3 3.3 GO:0006116 NADH oxidation(GO:0006116)
0.3 1.0 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.3 1.0 GO:1904668 positive regulation of mitotic nuclear division(GO:0045840) positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.3 1.6 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.3 0.6 GO:0030541 plasmid partitioning(GO:0030541)
0.3 0.6 GO:1903313 positive regulation of mRNA metabolic process(GO:1903313)
0.3 2.8 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.3 8.2 GO:0006885 regulation of pH(GO:0006885)
0.3 0.6 GO:0000092 mitotic anaphase B(GO:0000092)
0.3 0.9 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.3 2.4 GO:0000372 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.3 3.3 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.3 2.6 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.3 0.9 GO:0043207 immune effector process(GO:0002252) immune system process(GO:0002376) response to virus(GO:0009615) response to external biotic stimulus(GO:0043207) defense response to virus(GO:0051607) response to other organism(GO:0051707) defense response to other organism(GO:0098542)
0.3 0.8 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.3 2.9 GO:0051320 mitotic S phase(GO:0000084) S phase(GO:0051320)
0.3 1.0 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.3 0.3 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2 1.5 GO:0006491 N-glycan processing(GO:0006491)
0.2 1.2 GO:0009098 leucine biosynthetic process(GO:0009098)
0.2 2.7 GO:0006817 phosphate ion transport(GO:0006817)
0.2 1.4 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.2 0.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 1.8 GO:0006857 oligopeptide transport(GO:0006857)
0.2 0.9 GO:0006279 premeiotic DNA replication(GO:0006279)
0.2 0.9 GO:0048313 Golgi inheritance(GO:0048313)
0.2 1.3 GO:0009099 valine biosynthetic process(GO:0009099)
0.2 0.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054) negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 3.5 GO:0030488 tRNA methylation(GO:0030488)
0.2 0.9 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.2 0.4 GO:0001015 snoRNA transcription from an RNA polymerase II promoter(GO:0001015)
0.2 0.8 GO:0001111 promoter clearance during DNA-templated transcription(GO:0001109) promoter clearance from RNA polymerase II promoter(GO:0001111)
0.2 0.6 GO:0006624 vacuolar protein processing(GO:0006624)
0.2 1.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 2.4 GO:0006415 translational termination(GO:0006415)
0.2 5.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.2 0.6 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.2 0.4 GO:0006048 UDP-N-acetylglucosamine metabolic process(GO:0006047) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 0.7 GO:0031032 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin structure organization(GO:0031032) actomyosin contractile ring organization(GO:0044837)
0.2 1.0 GO:0045292 7-methylguanosine mRNA capping(GO:0006370) mRNA cis splicing, via spliceosome(GO:0045292)
0.2 0.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.2 0.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 3.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 2.7 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.2 2.0 GO:0010970 establishment of localization by movement along microtubule(GO:0010970) nuclear migration along microtubule(GO:0030473) organelle transport along microtubule(GO:0072384)
0.2 0.6 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.2 1.9 GO:0006284 base-excision repair(GO:0006284)
0.2 0.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.2 0.6 GO:0019184 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.2 0.5 GO:0006567 threonine catabolic process(GO:0006567)
0.2 0.5 GO:0006311 meiotic gene conversion(GO:0006311)
0.2 0.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.4 GO:2000221 negative regulation of cell growth(GO:0030308) negative regulation of pseudohyphal growth(GO:2000221)
0.1 0.7 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.7 GO:0007329 positive regulation of transcription from RNA polymerase II promoter by pheromones(GO:0007329) positive regulation of transcription by pheromones(GO:0009371)
0.1 0.6 GO:0045141 meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.1 0.7 GO:0035392 maintenance of chromatin silencing(GO:0006344) maintenance of chromatin silencing at telomere(GO:0035392)
0.1 0.3 GO:0031385 regulation of termination of mating projection growth(GO:0031385)
0.1 0.7 GO:0007232 osmosensory signaling pathway via Sho1 osmosensor(GO:0007232)
0.1 0.3 GO:0030952 establishment or maintenance of actin cytoskeleton polarity(GO:0030950) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.1 1.0 GO:0034063 stress granule assembly(GO:0034063)
0.1 2.0 GO:0030474 spindle pole body duplication(GO:0030474)
0.1 1.5 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 0.3 GO:0031684 heterotrimeric G-protein complex cycle(GO:0031684)
0.1 1.7 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 1.6 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 1.0 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 2.1 GO:0015918 sterol transport(GO:0015918)
0.1 3.9 GO:0016126 steroid biosynthetic process(GO:0006694) sterol biosynthetic process(GO:0016126)
0.1 2.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.6 GO:0006783 porphyrin-containing compound biosynthetic process(GO:0006779) heme biosynthetic process(GO:0006783) tetrapyrrole biosynthetic process(GO:0033014)
0.1 0.7 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.6 GO:0072668 obsolete tubulin complex biogenesis(GO:0072668)
0.1 1.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 1.5 GO:0000011 vacuole inheritance(GO:0000011)
0.1 0.1 GO:0031382 mating projection assembly(GO:0031382)
0.1 2.7 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.1 3.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.5 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.3 GO:0015886 heme transport(GO:0015886)
0.1 0.8 GO:0006797 polyphosphate metabolic process(GO:0006797)
0.1 0.4 GO:1900436 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
0.1 1.2 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 1.8 GO:0006379 mRNA cleavage(GO:0006379)
0.1 1.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 1.0 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.1 GO:0015691 cadmium ion transport(GO:0015691)
0.1 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 0.4 GO:0015867 ATP transport(GO:0015867)
0.1 0.9 GO:0009636 response to toxic substance(GO:0009636)
0.1 1.2 GO:0034963 box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963)
0.1 0.1 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 0.4 GO:0046417 chorismate biosynthetic process(GO:0009423) chorismate metabolic process(GO:0046417)
0.1 0.2 GO:0071902 positive regulation of protein serine/threonine kinase activity(GO:0071902)
0.1 0.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.5 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.1 0.7 GO:0044091 ascospore-type prospore membrane assembly(GO:0032120) membrane biogenesis(GO:0044091) membrane assembly(GO:0071709)
0.1 0.3 GO:0090180 regulation of vitamin metabolic process(GO:0030656) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of sulfur metabolic process(GO:0051176) regulation of thiamine biosynthetic process(GO:0070623) positive regulation of thiamine biosynthetic process(GO:0090180)
0.1 1.5 GO:0042797 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 3.2 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 1.2 GO:0046839 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.1 GO:0043065 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.1 0.4 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.7 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 0.3 GO:0015833 peptide transport(GO:0015833)
0.1 0.3 GO:0016036 cellular response to phosphate starvation(GO:0016036)
0.1 0.3 GO:0043007 maintenance of rDNA(GO:0043007)
0.1 1.4 GO:0006414 translational elongation(GO:0006414)
0.1 0.1 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.1 0.1 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.1 0.4 GO:0044205 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.9 GO:0071028 nuclear mRNA surveillance(GO:0071028)
0.1 0.2 GO:0008216 spermidine metabolic process(GO:0008216)
0.1 1.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.2 GO:0046901 tetrahydrofolylpolyglutamate metabolic process(GO:0046900) tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.1 1.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.6 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 4.4 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 0.3 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 0.5 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.1 1.0 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 0.2 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.1 0.4 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.2 GO:0031134 sister chromatid biorientation(GO:0031134)
0.1 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.2 GO:0000080 mitotic G1 phase(GO:0000080) G1 phase(GO:0051318)
0.1 0.5 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.1 0.2 GO:0045896 regulation of transcription during mitosis(GO:0045896)
0.1 1.1 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 0.1 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.1 0.1 GO:0036213 actomyosin contractile ring contraction(GO:0000916) contractile ring contraction(GO:0036213)
0.1 0.6 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 0.2 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.1 0.8 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.6 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.0 GO:0061422 positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH(GO:0061422)
0.0 0.1 GO:0043244 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) negative regulation of protein complex disassembly(GO:0043242) regulation of protein complex disassembly(GO:0043244) barbed-end actin filament capping(GO:0051016) actin filament capping(GO:0051693)
0.0 0.7 GO:0033260 nuclear DNA replication(GO:0033260) cell cycle DNA replication(GO:0044786)
0.0 0.5 GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay(GO:0070481)
0.0 0.5 GO:0051666 actin cortical patch localization(GO:0051666)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680) iron ion transmembrane transport(GO:0034755)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.3 GO:1903338 regulation of cell wall organization or biogenesis(GO:1903338)
0.0 0.2 GO:0031138 negative regulation of conjugation(GO:0031135) negative regulation of conjugation with cellular fusion(GO:0031138) negative regulation of multi-organism process(GO:0043901)
0.0 1.0 GO:0051783 regulation of nuclear division(GO:0051783)
0.0 0.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.5 GO:0031929 TOR signaling(GO:0031929)
0.0 0.1 GO:0071454 response to anoxia(GO:0034059) intralumenal vesicle formation(GO:0070676) cellular response to anoxia(GO:0071454)
0.0 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0045744 termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032) negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559)
0.0 0.0 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0032973 amino acid export(GO:0032973)
0.0 0.3 GO:0006862 nucleotide transport(GO:0006862)
0.0 2.4 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.1 GO:1901658 nucleoside catabolic process(GO:0009164) glycosyl compound catabolic process(GO:1901658)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.2 GO:0009231 riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231)
0.0 0.1 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.1 GO:0034661 rRNA catabolic process(GO:0016075) ncRNA catabolic process(GO:0034661)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0010182 cellular glucose homeostasis(GO:0001678) carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593) cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939) pantothenate biosynthetic process(GO:0015940)
0.0 0.0 GO:0031055 chromatin remodeling at centromere(GO:0031055)
0.0 0.1 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0007009 plasma membrane organization(GO:0007009)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.7 GO:0051726 regulation of cell cycle(GO:0051726)
0.0 0.1 GO:0009416 response to UV(GO:0009411) response to light stimulus(GO:0009416)
0.0 0.1 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.0 GO:0033241 regulation of cellular amine catabolic process(GO:0033241)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.8 GO:0000747 conjugation with cellular fusion(GO:0000747)
0.0 0.3 GO:0007105 cytokinesis, site selection(GO:0007105)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0051193 regulation of glycolytic process(GO:0006110) regulation of nucleoside metabolic process(GO:0009118) regulation of nucleotide catabolic process(GO:0030811) regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196) regulation of ATP metabolic process(GO:1903578)
0.0 0.0 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0009312 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
0.0 0.5 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.0 0.1 GO:0006057 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.1 GO:0000162 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:0043038 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0043687 C-terminal protein amino acid modification(GO:0018410) post-translational protein modification(GO:0043687)
0.0 0.0 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0007323 peptide pheromone maturation(GO:0007323)
0.0 0.0 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 17.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.8 14.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.8 2.5 GO:0030428 cell septum(GO:0030428)
0.7 2.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.7 2.7 GO:0030892 mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990)
0.7 2.0 GO:0070545 PeBoW complex(GO:0070545)
0.6 1.7 GO:0005827 polar microtubule(GO:0005827) tubulin complex(GO:0045298)
0.5 3.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.5 42.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 2.6 GO:0042555 MCM complex(GO:0042555)
0.4 2.5 GO:0035339 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
0.4 1.6 GO:0031518 CBF3 complex(GO:0031518)
0.4 3.6 GO:0000144 cellular bud neck septin ring(GO:0000144)
0.4 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.4 1.6 GO:0044462 cell wall part(GO:0044426) external encapsulating structure part(GO:0044462)
0.4 2.2 GO:0005940 septin ring(GO:0005940)
0.4 1.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.4 1.4 GO:0005880 nuclear microtubule(GO:0005880)
0.4 1.1 GO:0030874 nucleolar chromatin(GO:0030874)
0.3 21.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 1.4 GO:0000811 GINS complex(GO:0000811)
0.3 1.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 1.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 1.3 GO:0033597 mitotic checkpoint complex(GO:0033597)
0.3 2.5 GO:0042597 periplasmic space(GO:0042597)
0.3 1.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 0.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 1.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 0.8 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.3 0.8 GO:0033186 CAF-1 complex(GO:0033186)
0.3 1.3 GO:0005871 kinesin complex(GO:0005871)
0.2 1.2 GO:0032545 CURI complex(GO:0032545)
0.2 1.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 1.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 0.9 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.2 0.5 GO:0000786 nucleosome(GO:0000786)
0.2 1.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 0.9 GO:0055087 Ski complex(GO:0055087)
0.2 0.8 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.2 1.5 GO:0034455 t-UTP complex(GO:0034455)
0.2 1.0 GO:0034518 RNA cap binding complex(GO:0034518)
0.2 1.4 GO:0000346 transcription export complex(GO:0000346)
0.2 1.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 1.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 2.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 0.4 GO:0033309 SBF transcription complex(GO:0033309)
0.2 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 0.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 1.9 GO:0000792 heterochromatin(GO:0000792)
0.2 1.1 GO:0016459 myosin complex(GO:0016459)
0.2 1.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 0.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 0.5 GO:0032301 MutSalpha complex(GO:0032301)
0.2 0.8 GO:0005823 central plaque of spindle pole body(GO:0005823)
0.2 0.9 GO:0000136 alpha-1,6-mannosyltransferase complex(GO:0000136)
0.2 0.5 GO:0043529 GET complex(GO:0043529)
0.1 0.3 GO:0030869 RENT complex(GO:0030869)
0.1 5.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.6 GO:0035361 Cul8-RING ubiquitin ligase complex(GO:0035361)
0.1 0.9 GO:0000133 polarisome(GO:0000133)
0.1 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 1.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.4 GO:0000262 cytoplasmic chromosome(GO:0000229) mitochondrial chromosome(GO:0000262)
0.1 1.2 GO:0042729 DASH complex(GO:0042729)
0.1 0.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 2.1 GO:0070210 Rpd3L-Expanded complex(GO:0070210)
0.1 0.8 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 3.3 GO:0005844 polysome(GO:0005844)
0.1 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 1.7 GO:0005657 replication fork(GO:0005657)
0.1 6.8 GO:0005576 extracellular region(GO:0005576)
0.1 0.9 GO:0000243 commitment complex(GO:0000243)
0.1 1.8 GO:0009277 fungal-type cell wall(GO:0009277)
0.1 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.6 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 9.4 GO:0005935 cellular bud neck(GO:0005935)
0.1 0.3 GO:0097196 Shu complex(GO:0097196)
0.1 0.1 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.2 GO:0031415 NatA complex(GO:0031415)
0.1 1.0 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 0.2 GO:0097255 R2TP complex(GO:0097255)
0.1 0.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.5 GO:0030659 vesicle membrane(GO:0012506) cytoplasmic vesicle membrane(GO:0030659)
0.1 0.7 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.3 GO:0000500 RNA polymerase I upstream activating factor complex(GO:0000500)
0.1 0.3 GO:0034448 EGO complex(GO:0034448)
0.1 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 1.8 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.7 GO:0016586 RSC complex(GO:0016586)
0.0 5.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.5 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 2.2 GO:0000785 chromatin(GO:0000785)
0.0 0.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0030135 coated vesicle(GO:0030135)
0.0 0.1 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.0 0.0 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.0 GO:0031391 Elg1 RFC-like complex(GO:0031391)
0.0 0.0 GO:0005824 outer plaque of spindle pole body(GO:0005824)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.0 GO:0000417 HIR complex(GO:0000417)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.8 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.2 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0070568 guanylyltransferase activity(GO:0070568)
1.5 9.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.0 4.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
1.0 3.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
1.0 2.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.7 2.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.7 17.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.6 2.6 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.6 7.6 GO:0005199 structural constituent of cell wall(GO:0005199)
0.6 2.5 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.6 2.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.6 19.1 GO:0046982 protein heterodimerization activity(GO:0046982)
0.6 4.6 GO:0031406 carboxylic acid binding(GO:0031406) organic acid binding(GO:0043177)
0.6 2.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.6 1.7 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.5 1.6 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.5 2.1 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.5 3.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.5 2.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.5 2.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.5 1.4 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.4 1.3 GO:0004100 chitin synthase activity(GO:0004100)
0.4 2.6 GO:0016408 C-acyltransferase activity(GO:0016408)
0.4 1.7 GO:1904680 peptide transmembrane transporter activity(GO:1904680)
0.4 2.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.4 3.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.4 2.4 GO:0042124 glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124)
0.4 3.8 GO:0032934 steroid binding(GO:0005496) sterol binding(GO:0032934)
0.4 1.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.4 16.1 GO:0019843 rRNA binding(GO:0019843)
0.3 1.0 GO:0000339 RNA cap binding(GO:0000339)
0.3 1.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.3 3.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 0.6 GO:0000403 Y-form DNA binding(GO:0000403)
0.3 0.8 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.3 0.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.3 1.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 48.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 2.6 GO:0019239 deaminase activity(GO:0019239)
0.3 1.0 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.2 GO:0070403 NAD+ binding(GO:0070403)
0.2 0.7 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.2 1.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 0.9 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.2 1.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 0.7 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 0.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 1.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 1.0 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.2 1.0 GO:0000146 microfilament motor activity(GO:0000146)
0.2 1.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 1.0 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 0.8 GO:0008312 7S RNA binding(GO:0008312)
0.2 0.7 GO:0005034 osmosensor activity(GO:0005034)
0.2 0.5 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.2 0.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 0.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 0.9 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 0.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 0.5 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.7 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.2 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 11.2 GO:0003924 GTPase activity(GO:0003924)
0.2 0.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 1.5 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 0.6 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.7 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.8 GO:0001139 transcription factor activity, core RNA polymerase II recruiting(GO:0001139)
0.1 1.2 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 5.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) fatty acid ligase activity(GO:0015645)
0.1 0.4 GO:0004338 glucan exo-1,3-beta-glucosidase activity(GO:0004338)
0.1 1.1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.8 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.1 GO:0019003 GDP binding(GO:0019003)
0.1 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.6 GO:0016866 intramolecular transferase activity(GO:0016866)
0.1 0.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 2.1 GO:0008017 microtubule binding(GO:0008017)
0.1 1.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.3 GO:0042973 beta-glucosidase activity(GO:0008422) glucan endo-1,3-beta-D-glucosidase activity(GO:0042973)
0.1 4.1 GO:0030674 protein binding, bridging(GO:0030674)
0.1 1.7 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 1.4 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 3.3 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.9 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.1 0.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.1 0.3 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 1.4 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.5 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.6 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.6 GO:0051920 thioredoxin peroxidase activity(GO:0008379) peroxiredoxin activity(GO:0051920)
0.1 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 1.6 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 0.4 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 0.3 GO:0001168 transcription factor activity, RNA polymerase I upstream control element sequence-specific binding(GO:0001168)
0.1 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 1.2 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 0.2 GO:0019901 protein kinase binding(GO:0019901)
0.1 0.2 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.1 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.6 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.5 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 0.9 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
0.1 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.4 GO:0000049 tRNA binding(GO:0000049)
0.1 0.7 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 2.0 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 0.2 GO:0005253 anion channel activity(GO:0005253) voltage-gated anion channel activity(GO:0008308)
0.1 0.5 GO:0015266 protein channel activity(GO:0015266)
0.1 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.4 GO:0051015 actin filament binding(GO:0051015)
0.1 1.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.7 GO:0005048 signal sequence binding(GO:0005048)
0.1 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 2.0 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 1.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.1 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0000149 SNARE binding(GO:0000149)
0.0 1.6 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0018456 aryl-alcohol dehydrogenase (NAD+) activity(GO:0018456)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.7 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.0 0.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004805 trehalose-phosphatase activity(GO:0004805)
0.0 0.3 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0015038 glutathione-disulfide reductase activity(GO:0004362) peptide disulfide oxidoreductase activity(GO:0015037) glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 2.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.4 GO:0032561 GTP binding(GO:0005525) guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.2 GO:0003779 actin binding(GO:0003779)
0.0 0.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0005506 iron ion binding(GO:0005506)
0.0 0.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0008289 lipid binding(GO:0008289)
0.0 0.2 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.1 GO:0017069 snRNA binding(GO:0017069)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.8 0.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 1.8 PID ATR PATHWAY ATR signaling pathway
0.2 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.2 0.7 PID E2F PATHWAY E2F transcription factor network
0.2 0.5 PID SHP2 PATHWAY SHP2 signaling
0.2 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 0.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 0.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.3 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 0.2 PID P73PATHWAY p73 transcription factor network
0.1 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.1 PID MYC PATHWAY C-MYC pathway
0.0 0.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.6 2.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.5 1.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.5 1.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.5 7.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.4 2.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 2.3 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.3 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 1.5 REACTOME TRANSLATION Genes involved in Translation
0.2 0.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 0.6 REACTOME SIGNALLING TO ERKS Genes involved in Signalling to ERKs
0.2 0.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 0.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME CELL CYCLE MITOTIC Genes involved in Cell Cycle, Mitotic
0.0 0.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR