Results for SWI5
Z-value: 0.84
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Transcription factors associated with SWI5
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SWI5
|
S000002553 | Transcription factor that recruits Mediator and Swi/Snf complexes |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YFR055W Show fit | 8.43 |
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner |
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| YFR056C Show fit | 8.12 |
Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W |
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| YER124C Show fit | 5.91 |
Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall |
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| YDL055C Show fit | 5.78 |
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure |
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| YLR154C Show fit | 4.64 |
Ribonuclease H2 subunit, required for RNase H2 activity |
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| YNL178W Show fit | 3.79 |
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins |
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| YIR021W Show fit | 3.69 |
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA |
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| YLR154W-C Show fit | 3.54 |
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand |
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| YBR158W Show fit | 3.46 |
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN) |
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| YNL327W Show fit | 3.43 |
Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner |
Network of associatons between targets according to the STRING database.
First level regulatory network of SWI5
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 41.3 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 1.4 | 15.1 | GO:0007109 | obsolete cytokinesis, completion of separation(GO:0007109) |
| 0.5 | 8.7 | GO:0006407 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
| 2.8 | 8.4 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 1.5 | 6.2 | GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461) |
| 1.9 | 5.8 | GO:0019673 | GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673) |
| 0.8 | 5.4 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.5 | 3.9 | GO:0000372 | Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376) |
| 0.3 | 3.9 | GO:0090529 | barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529) |
| 0.2 | 3.7 | GO:0001100 | negative regulation of exit from mitosis(GO:0001100) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 35.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.4 | 25.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 14.3 | GO:0005933 | cellular bud(GO:0005933) |
| 0.1 | 6.5 | GO:0005576 | extracellular region(GO:0005576) |
| 2.1 | 6.2 | GO:0030428 | cell septum(GO:0030428) |
| 1.8 | 5.3 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.1 | 3.7 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.2 | 3.2 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.1 | 2.8 | GO:0005844 | polysome(GO:0005844) |
| 0.1 | 2.2 | GO:0005811 | lipid particle(GO:0005811) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 43.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.3 | 13.0 | GO:0019843 | rRNA binding(GO:0019843) |
| 1.5 | 9.2 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 1.9 | 5.8 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
| 1.3 | 5.3 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 1.0 | 3.8 | GO:0042973 | glucan endo-1,3-beta-D-glucosidase activity(GO:0042973) |
| 0.6 | 3.8 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.2 | 3.7 | GO:0015926 | glucosidase activity(GO:0015926) |
| 0.2 | 3.6 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 0.2 | 3.3 | GO:0004520 | endodeoxyribonuclease activity(GO:0004520) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.7 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.3 | 1.0 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.2 | 0.9 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.2 | 0.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.3 | 0.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.6 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.2 | 0.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 0.3 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 0.2 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 0.2 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 15.7 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.9 | 2.7 | REACTOME INSULIN RECEPTOR SIGNALLING CASCADE | Genes involved in Insulin receptor signalling cascade |
| 0.4 | 1.1 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.2 | 0.8 | REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
| 0.2 | 0.7 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.2 | 0.7 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.2 | 0.7 | REACTOME SIGNALING BY GPCR | Genes involved in Signaling by GPCR |
| 0.0 | 0.5 | REACTOME M G1 TRANSITION | Genes involved in M/G1 Transition |
| 0.1 | 0.4 | REACTOME METABOLISM OF RNA | Genes involved in Metabolism of RNA |
| 0.2 | 0.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |