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Results for YLL054C

Z-value: 0.84

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Transcription factors associated with YLL054C

Gene Symbol Gene ID Gene Info
S000003977 Putative protein of unknown function with similarity to Pip2p

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
YLL054C-0.854.5e-08Click!

Activity profile of YLL054C motif

Sorted Z-values of YLL054C motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YLR154W-A 7.60 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154W-B 7.34 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154C 6.52
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YLR349W 5.34 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified ORF DIC1/YLR348C
YJR094W-A 5.07
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YLR348C 5.00
DIC1
Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix
YLL045C 4.78
RPL8B
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
YLR154W-C 4.53
TAR1
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
YPL250W-A 4.38 Identified by fungal homology and RT-PCR
YKR092C 4.11
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YOR101W 3.81
RAS1
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes
YNR013C 3.76
PHO91
Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YNL178W 3.73
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YOR063W 3.63
RPL3
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
YHR141C 3.31
RPL42B
Protein component of the large (60S) ribosomal subunit, identical to Rpl42Ap and has similarity to rat L44; required for propagation of the killer toxin-encoding M1 double-stranded RNA satellite of the L-A double-stranded RNA virus
YDR037W 3.28
KRS1
Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis
YLR413W 3.21 Putative protein of unknown function; YLR413W is not an essential gene
YLR301W 2.87 Protein of unknown function that interacts with Sec72p
YIR021W 2.83
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YGR280C 2.83
PXR1
Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain
YJL136C 2.80
RPS21B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein
YER131W 2.77
RPS26B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
YHR216W 2.75
IMD2
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
YGR148C 2.75
RPL24B
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YHR136C 2.73
SPL2
Protein with similarity to cyclin-dependent kinase inhibitors, overproduction suppresses a plc1 null mutation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YFL022C 2.48
FRS2
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YPL249C-A 2.42
RPL36B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Ap and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA
YPR148C 2.41 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YMR108W 2.34
ILV2
Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control
YNL090W 2.29
RHO2
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involved in the establishment of cell polarity and in microtubule assembly
YDR418W 2.24
RPL12B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins
YPR074C 2.21
TKL1
Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
YBR158W 2.18
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YGR118W 2.10
RPS23A
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal
YLR048W 2.08
RPS0B
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
YIL056W 2.08
VHR1
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations
YJL153C 2.05
INO1
Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
YGL209W 1.94
MIG2
Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
YIL133C 1.93
RPL16A
N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p
YFL015W-A 1.92 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YFL015C 1.91 Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene
YDL075W 1.90
RPL31A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YOR234C 1.90
RPL33B
Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable
YOL014W 1.89 Putative protein of unknown function
YMR102C 1.86 Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
YMR099C 1.86 Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase), likely involved in carbohydrate metabolism; GFP-fusion protein localizes to both the nucleus and cytoplasm and is induced in response to the DNA-damaging agent MMS
YIL118W 1.81
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YHR137W 1.76
ARO9
Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism
YIL121W 1.62
QDR2
Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake
YMR009W 1.60
ADI1
Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions
YKL110C 1.59
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YPL062W 1.54 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation
YKL120W 1.53
OAC1
Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and thiosulfate; member of the mitochondrial carrier family
YER146W 1.53
LSM5
Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA
YGL035C 1.51
MIG1
Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase
YOL101C 1.47
IZH4
Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism
YKR093W 1.44
PTR2
Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p
YPL263C 1.43
KEL3
Cytoplasmic protein of unknown function
YNL302C 1.36
RPS19B
Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Ap
YKL106W 1.36
AAT1
Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis
YPL137C 1.35
GIP3
Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments
YKL218C 1.34
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YJL212C 1.33
OPT1
Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family
YOL127W 1.32
RPL25
Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif
YJL115W 1.32
ASF1
Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition
YMR100W 1.31
MUB1
Protein of unknown function, deletion causes multi-budding phenotype; has similarity to Aspergillus nidulans samB gene
YER102W 1.27
RPS8B
Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and has similarity to rat S8 ribosomal protein
YIL069C 1.27
RPS24B
Protein component of the small (40S) ribosomal subunit; identical to Rps24Ap and has similarity to rat S24 ribosomal protein
YDR144C 1.25
MKC7
GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p
YNL153C 1.25
GIM3
Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
YDL173W 1.24 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDL173W is not an essential gene
YGR138C 1.21
TPO2
Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily
YPL220W 1.18
RPL1A
N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Bp and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal
YLR344W 1.15
RPL26A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Bp and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA
YFL016C 1.14
MDJ1
Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones
YGL201C 1.14
MCM6
Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
YHR020W 1.14 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to proline-tRNA ligase; YHR020W is an essential gene
YDL055C 1.13
PSA1
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure
YKL068W-A 1.11 Putative protein of unknown function; identified by homology to Ashbya gossypii
YGR017W 1.11 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm
YGR052W 1.09
FMP48
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation
YNL089C 1.08 Dubious open reading frame unlikely to encode a functional protein; almost completely overlaps YNL090W/RHO2 which encodes a small GTPase of the Rho/Rac subfamily of Ras-like proteins
YKL096W-A 1.08
CWP2
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored
YML024W 1.06
RPS17A
Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Bp and has similarity to rat S17 ribosomal protein
YMR267W 1.06
PPA2
Mitochondrial inorganic pyrophosphatase, required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate
YLR448W 1.06
RPL6B
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA
YLL043W 1.05
FPS1
Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glycerol and in uptake of acetic acid and the trivalent metalloids arsenite and antimonite; phosphorylated by Hog1p MAPK under acetate stress
YAL038W 1.05
CDC19
Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
YMR121C 1.04
RPL15B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
YEL054C 1.03
RPL12A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Bp; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins
YLL028W 1.03
TPO1
Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane
YJL190C 1.02
RPS22A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins
YJR047C 1.02
ANB1
Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions
YOR254C 1.00
SEC63
Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER
YBL063W 1.00
KIP1
Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p
YPR063C 0.99 ER-localized protein of unknown function
YOR320C 0.99
GNT1
N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus
YGR140W 0.98
CBF2
Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
YCR099C 0.98 Putative protein of unknown function
YGL034C 0.96 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YER036C 0.95
ARB1
ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome biogenesis, has similarity to Gcn20p; shuttles from nucleus to cytoplasm, physically interacts with Tif6p, Lsg1p
YGR242W 0.94 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C
YPL004C 0.93
LSP1
Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways
YGR050C 0.93 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YBR048W 0.90
RPS11B
Protein component of the small (40S) ribosomal subunit; identical to Rps11Ap and has similarity to E. coli S17 and rat S11 ribosomal proteins
YPL136W 0.90 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene GIP3/YPL137C
YBR106W 0.88
PHO88
Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations
YOR163W 0.88
DDP1
Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases
YML063W 0.87
RPS1B
Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein
YCL024W 0.87
KCC4
Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p
YPL003W 0.86
ULA1
Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation
YHR181W 0.86
SVP26
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment
YKR075C 0.85 Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YHR019C 0.85
DED81
Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA
YGR097W 0.85
ASK10
Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes
YPL170W 0.85
DAP1
Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis
YHR142W 0.84
CHS7
Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER
YGR241C 0.84
YAP1802
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family
YKR074W 0.83
AIM29
Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
YDR450W 0.83
RPS18A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Bp and has similarity to E. coli S13 and rat S18 ribosomal proteins
YER130C 0.83 Hypothetical protein
YDL137W 0.81
ARF2
ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf1p
YJR123W 0.80
RPS5
Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins
YKR038C 0.79
KAE1
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
YPR074W-A 0.79 Hypothetical protein identified by homology
YCL023C 0.78 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF KCC4
YFR036W-A 0.78 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene RSC8
YOL125W 0.78
TRM13
2'-O-methyltransferase responsible for modification of tRNA at position 4; exhibits no obvious similarity to other known methyltransferases
YDR215C 0.77 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein
YNL189W 0.76
SRP1
Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation
YER045C 0.76
ACA1
Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources
YGR128C 0.76
UTP8
Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
YOR092W 0.75
ECM3
Non-essential protein of unknown function; involved in signal transduction and the genotoxic response; induced rapidly in response to treatment with 8-methoxypsoralen and UVA irradiation
YOL005C 0.75
RPB11
RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit
YER049W 0.74
TPA1
Protein of unknown function; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; has a role in translation termination efficiency, mRNA poly(A) tail length and mRNA stability
YMR208W 0.72
ERG12
Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
YJL222W 0.71
VTH2
Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in vacuolar protein sorting
YER046W 0.71
SPO73
Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensible for both nuclear divisions during meiosis
YGR004W 0.71
PEX31
Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p
YDR297W 0.71
SUR2
Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis
YGR051C 0.70 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene
YLR025W 0.70
SNF7
One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes
YGR034W 0.69
RPL26B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA
YOR119C 0.69
RIO1
Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA
YGR055W 0.68
MUP1
High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake
YHR162W 0.68 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion
YDR156W 0.67
RPA14
RNA polymerase I subunit A14
YEL020C-B 0.67 Dubious open reading frame unlikely to encode a protein; partially overlaps verified gene YEL020W-A; identified by fungal homology and RT-PCR
YFL014W 0.65
HSP12
Plasma membrane localized protein that protects membranes from desiccation; induced by heat shock, oxidative stress, osmostress, stationary phase entry, glucose depletion, oleate and alcohol; regulated by the HOG and Ras-Pka pathways
YOR273C 0.64
TPO4
Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily
YOR340C 0.64
RPA43
RNA polymerase I subunit A43
YJL173C 0.64
RFA3
Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination
YBR096W 0.62 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER
YHR127W 0.62 Protein of unknown function; localizes to the nucleus
YNL065W 0.62
AQR1
Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids
YKL190W 0.61
CNB1
Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1
YML126C 0.61
ERG13
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis
YNL118C 0.61
DCP2
Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family
YDL241W 0.61 Putative protein of unknown function; YDL241W is not an essential gene
YBL032W 0.61
HEK2
RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length
YPR025C 0.60
CCL1
Cyclin associated with protein kinase Kin28p, which is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters
YKL001C 0.59
MET14
Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism
YDR451C 0.59
YHP1
One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval
YGR271C-A 0.59
EFG1
Protein of unknown function; null mutant is sensitive to hydroxyurea and is delayed in recovering from alpha-factor arrest; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus
YGR139W 0.59 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YNL304W 0.58
YPT11
Rab-type small GTPase that interacts with the C-terminal tail domain of Myo2p to mediate distribution of mitochondria to daughter cells
YIL009W 0.58
FAA3
Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YMR012W 0.57
CLU1
eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant
YHR045W 0.57 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum
YLR110C 0.56
CCW12
Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor
YCR101C 0.56 Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene
YJR094C 0.56
IME1
Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p
YGR014W 0.55
MSB2
Mucin family member involved in the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; also functions as an osmosensor in parallel to the Sho1p-mediated pathway; potential Cdc28p substrate
YCR090C 0.55 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YCR090C is not an essential gene
YOL086C 0.54
ADH1
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
YBR011C 0.53
IPP1
Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase
YOR274W 0.52
MOD5
Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms
YKL063C 0.52 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
YEL062W 0.51
NPR2
Protein with a possible role in regulating expression of nitrogen permeases; transcription is induced in response to proline and urea; contains two PEST sequences; null mutant is resistant to cisplatin and doxorubicin
YPR195C 0.50 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YEL056W 0.50
HAT2
Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing
YGL172W 0.49
NUP49
Subunit of the Nsp1p-Nup57p-Nup49p-Nic96p subcomplex of the nuclear pore complex (NPC), required for nuclear export of ribosomes
YJL223C 0.49
PAU1
Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
YGL253W 0.49
HXK2
Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene
YGL031C 0.47
RPL24A
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YAR002W 0.47
NUP60
Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; potential Cdc28p substrate; involved in telomere maintenance
YLL027W 0.47
ISA1
Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources
YDR074W 0.46
TPS2
Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway
YDL047W 0.46
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YOR306C 0.46
MCH5
Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport
YDL023C 0.45 Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance
YGR180C 0.45
RNR4
Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
YPL081W 0.44
RPS9A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Bp and has similarity to E. coli S4 and rat S9 ribosomal proteins
YMR122W-A 0.44 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and endoplasmic reticulum
YJR145C 0.43
RPS4A
Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
YKL143W 0.43
LTV1
Component of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; required for ribosomal small subunit export from nucleus; required for growth at low temperature
YIL009C-A 0.42
EST3
Component of the telomerase holoenzyme, involved in telomere replication
YEL063C 0.41
CAN1
Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance
YIR019C 0.41
MUC1
GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)
YGL030W 0.40
RPL30
Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript

Network of associatons between targets according to the STRING database.

First level regulatory network of YLL054C

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
1.2 4.9 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
1.0 6.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
1.0 6.7 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.9 2.8 GO:0046039 GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039)
0.9 0.9 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.9 3.5 GO:0036170 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
0.8 3.3 GO:0014070 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
0.8 2.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.7 2.9 GO:0000296 spermine transport(GO:0000296)
0.7 2.8 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.6 9.5 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.6 1.8 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.5 4.6 GO:0006817 phosphate ion transport(GO:0006817)
0.5 1.4 GO:0006531 asparagine biosynthetic process(GO:0006529) aspartate metabolic process(GO:0006531)
0.4 2.3 GO:0009099 valine biosynthetic process(GO:0009099)
0.4 2.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.4 1.5 GO:0090338 regulation of formin-nucleated actin cable assembly(GO:0090337) positive regulation of formin-nucleated actin cable assembly(GO:0090338)
0.4 1.9 GO:0015793 glycerol transport(GO:0015793)
0.4 2.7 GO:0043457 regulation of cellular respiration(GO:0043457)
0.4 1.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.4 2.8 GO:0000376 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.3 1.0 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.3 1.0 GO:0030541 plasmid partitioning(GO:0030541)
0.3 1.6 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.3 44.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.3 1.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.3 1.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.3 2.8 GO:0006857 oligopeptide transport(GO:0006857)
0.2 0.2 GO:0032231 regulation of actin filament bundle assembly(GO:0032231) positive regulation of actin filament bundle assembly(GO:0032233)
0.2 0.9 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
0.2 0.7 GO:0034059 response to anoxia(GO:0034059) cellular response to anoxia(GO:0071454)
0.2 1.1 GO:0050810 regulation of steroid metabolic process(GO:0019218) regulation of ergosterol biosynthetic process(GO:0032443) regulation of steroid biosynthetic process(GO:0050810)
0.2 1.6 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.2 1.2 GO:0045116 protein neddylation(GO:0045116)
0.2 0.6 GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.2 1.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 1.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.2 0.9 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.2 3.7 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.2 0.7 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.2 2.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 0.5 GO:0032006 regulation of TOR signaling(GO:0032006)
0.2 1.5 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.2 0.5 GO:0015755 fructose transport(GO:0015755)
0.2 4.0 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.2 0.2 GO:1902931 negative regulation of alcohol biosynthetic process(GO:1902931)
0.2 0.8 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.1 0.4 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.1 2.2 GO:0001100 negative regulation of exit from mitosis(GO:0001100)
0.1 0.6 GO:0048313 Golgi inheritance(GO:0048313)
0.1 0.1 GO:1901799 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799)
0.1 0.6 GO:0098740 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.1 0.1 GO:0033239 negative regulation of cellular amine metabolic process(GO:0033239)
0.1 1.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:0034030 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1 1.3 GO:0006116 NADH oxidation(GO:0006116)
0.1 1.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.6 GO:0007155 cell adhesion(GO:0007155) biological adhesion(GO:0022610)
0.1 1.1 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 1.0 GO:0000921 septin ring assembly(GO:0000921)
0.1 0.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.5 GO:0060188 regulation of protein desumoylation(GO:0060188)
0.1 0.6 GO:0007232 osmosensory signaling pathway via Sho1 osmosensor(GO:0007232)
0.1 0.6 GO:0032973 amino acid export(GO:0032973)
0.1 0.4 GO:0015809 arginine transport(GO:0015809)
0.1 0.2 GO:1901351 regulation of phosphatidylglycerol biosynthetic process(GO:1901351) negative regulation of phosphatidylglycerol biosynthetic process(GO:1901352)
0.1 0.8 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1 1.1 GO:0006415 translational termination(GO:0006415)
0.1 1.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.3 GO:0042710 biofilm formation(GO:0042710)
0.1 1.0 GO:0007004 telomere maintenance via telomerase(GO:0007004)
0.1 1.0 GO:0051278 fungal-type cell wall chitin biosynthetic process(GO:0034221) fungal-type cell wall polysaccharide biosynthetic process(GO:0051278) fungal-type cell wall polysaccharide metabolic process(GO:0071966)
0.1 0.9 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.2 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.1 1.9 GO:0009267 cellular response to starvation(GO:0009267)
0.1 0.2 GO:1900062 regulation of cell aging(GO:0090342) regulation of replicative cell aging(GO:1900062)
0.1 1.0 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.5 GO:0009102 biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102)
0.1 1.2 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.1 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.5 GO:0000080 mitotic G1 phase(GO:0000080) G1 phase(GO:0051318)
0.1 1.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 0.6 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.2 GO:0009097 isoleucine biosynthetic process(GO:0009097)
0.1 0.2 GO:0015833 peptide transport(GO:0015833)
0.1 0.6 GO:0008299 isoprenoid metabolic process(GO:0006720) isoprenoid biosynthetic process(GO:0008299)
0.1 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.4 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.1 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 0.4 GO:0000032 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506)
0.1 1.4 GO:0046939 nucleotide phosphorylation(GO:0046939)
0.0 1.1 GO:0006885 regulation of pH(GO:0006885)
0.0 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.5 GO:0006547 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.0 0.2 GO:0001402 signal transduction involved in filamentous growth(GO:0001402)
0.0 0.4 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.1 GO:0001933 negative regulation of protein phosphorylation(GO:0001933)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0007119 budding cell isotropic bud growth(GO:0007119)
0.0 0.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.0 2.0 GO:0007015 actin filament organization(GO:0007015)
0.0 0.1 GO:0000092 mitotic anaphase B(GO:0000092)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344) maintenance of chromatin silencing at telomere(GO:0035392)
0.0 0.5 GO:0031929 TOR signaling(GO:0031929)
0.0 0.3 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0071043 CUT catabolic process(GO:0071034) nuclear polyadenylation-dependent CUT catabolic process(GO:0071039) CUT metabolic process(GO:0071043)
0.0 3.7 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 1.9 GO:0051302 regulation of cell division(GO:0051302)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.5 GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion(GO:0000754) adaptation of signaling pathway(GO:0023058)
0.0 0.2 GO:0007009 plasma membrane organization(GO:0007009)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0009312 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
0.0 0.2 GO:0007323 peptide pheromone maturation(GO:0007323)
0.0 0.1 GO:0036498 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) IRE1-mediated unfolded protein response(GO:0036498) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:0000162 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.0 0.6 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0000743 nuclear migration involved in conjugation with cellular fusion(GO:0000743)
0.0 0.1 GO:0071709 ascospore-type prospore membrane assembly(GO:0032120) membrane biogenesis(GO:0044091) membrane assembly(GO:0071709)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.8 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.5 GO:0006413 translational initiation(GO:0006413)
0.0 0.5 GO:0006348 chromatin silencing at telomere(GO:0006348)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.5 39.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 24.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 1.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 1.0 GO:0031207 endoplasmic reticulum Sec complex(GO:0031205) Sec62/Sec63 complex(GO:0031207)
0.2 1.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 1.0 GO:0031518 CBF3 complex(GO:0031518)
0.2 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.6 GO:0070985 TFIIK complex(GO:0070985)
0.2 1.1 GO:0042555 MCM complex(GO:0042555)
0.2 1.1 GO:0005871 kinesin complex(GO:0005871)
0.2 1.5 GO:0005688 U6 snRNP(GO:0005688)
0.2 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.2 1.2 GO:0016272 prefoldin complex(GO:0016272)
0.2 4.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.2 0.8 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.2 GO:0033101 cellular bud membrane(GO:0033101)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.5 GO:0097042 extrinsic component of fungal-type vacuolar membrane(GO:0097042)
0.1 0.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.8 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.4 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.4 GO:0034448 EGO complex(GO:0034448)
0.1 1.4 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.1 GO:0005940 septin ring(GO:0005940)
0.1 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 8.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0032126 eisosome(GO:0032126)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827) tubulin complex(GO:0045298)
0.0 0.1 GO:0035649 Nrd1 complex(GO:0035649)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0034967 Set3 complex(GO:0034967)
0.0 0.7 GO:0030118 clathrin coat(GO:0030118)
0.0 0.5 GO:0070210 Rpd3L-Expanded complex(GO:0070210)
0.0 0.1 GO:0034518 RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0044426 cell wall part(GO:0044426) external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0045254 mitochondrial pyruvate dehydrogenase complex(GO:0005967) pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 3.9 GO:0005933 cellular bud(GO:0005933)
0.0 0.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0016586 RSC complex(GO:0016586)
0.0 2.2 GO:0005840 ribosome(GO:0005840)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.5 GO:0043332 mating projection tip(GO:0043332)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.3 3.8 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.9 2.8 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.9 2.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.8 2.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.7 6.5 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.7 2.9 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.7 2.1 GO:0016872 intramolecular lyase activity(GO:0016872)
0.6 3.2 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.6 3.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.6 3.6 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.4 1.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.4 1.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.4 1.2 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.4 1.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.3 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 1.3 GO:0016854 ammonia-lyase activity(GO:0016841) racemase and epimerase activity(GO:0016854)
0.3 0.3 GO:0051213 dioxygenase activity(GO:0051213)
0.3 1.5 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.3 2.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 0.9 GO:0072341 modified amino acid binding(GO:0072341)
0.3 60.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 1.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 0.2 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.2 3.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 0.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2 0.8 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.2 0.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 2.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 1.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.9 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:0005034 osmosensor activity(GO:0005034)
0.1 1.1 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 4.0 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.9 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 0.5 GO:0004396 hexokinase activity(GO:0004396)
0.1 2.3 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 8.4 GO:0003924 GTPase activity(GO:0003924)
0.1 0.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.2 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 1.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.2 GO:0000049 tRNA binding(GO:0000049)
0.1 0.8 GO:0031072 heat shock protein binding(GO:0031072)
0.1 1.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.8 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.2 GO:0000287 magnesium ion binding(GO:0000287)
0.1 0.4 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
0.1 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.2 GO:0004805 trehalose-phosphatase activity(GO:0004805)
0.1 0.2 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864) phosphatase inhibitor activity(GO:0019212)
0.1 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.4 GO:0031386 protein tag(GO:0031386)
0.1 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.9 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.3 GO:0005354 galactose transmembrane transporter activity(GO:0005354)
0.0 0.2 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.0 0.1 GO:0004691 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.3 GO:0015631 tubulin binding(GO:0015631)
0.0 0.2 GO:0008144 drug binding(GO:0008144)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 1.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.5 GO:0008289 lipid binding(GO:0008289)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 0.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.3 GO:0051287 NAD binding(GO:0051287)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.0 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.1 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 PID SHP2 PATHWAY SHP2 signaling
0.1 0.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 0.4 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 0.2 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 REACTOME SIGNALING BY INSULIN RECEPTOR Genes involved in Signaling by Insulin receptor
0.6 4.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.5 1.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.5 0.9 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.3 4.7 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.2 1.5 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.2 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 1.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 0.4 REACTOME GPCR LIGAND BINDING Genes involved in GPCR ligand binding
0.0 0.1 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.0 REACTOME RNA POL II TRANSCRIPTION Genes involved in RNA Polymerase II Transcription