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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Alx4

Z-value: 1.68

Motif logo

Transcription factors associated with Alx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000040310.13 Alx4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Alx4mm39_v1_chr2_+_93472657_934727330.601.0e-04Click!

Activity profile of Alx4 motif

Sorted Z-values of Alx4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Alx4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_87684299 16.19 ENSMUST00000020779.11
myeloperoxidase
chr5_-_138169253 9.54 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr13_-_100922910 9.31 ENSMUST00000174038.2
ENSMUST00000091295.14
ENSMUST00000072119.15
cyclin B1
chr7_+_44221791 7.52 ENSMUST00000002274.10
napsin A aspartic peptidase
chr15_+_89218601 7.22 ENSMUST00000023282.9
myo-inositol oxygenase
chr11_-_11920540 6.66 ENSMUST00000109653.8
growth factor receptor bound protein 10
chr6_-_41354538 6.60 ENSMUST00000096003.7
protease, serine 3
chr5_-_138169509 6.57 ENSMUST00000153867.8
minichromosome maintenance complex component 7
chr16_+_48692976 6.57 ENSMUST00000065666.6
resistin like gamma
chr4_+_135899678 6.47 ENSMUST00000061721.6
E2F transcription factor 2
chr10_-_62215631 6.40 ENSMUST00000143236.8
ENSMUST00000133429.8
ENSMUST00000132926.8
ENSMUST00000116238.9
hexokinase 1
chr11_-_106205320 6.24 ENSMUST00000167143.2
CD79B antigen
chr16_-_16687119 5.87 ENSMUST00000075017.5
pre-B lymphocyte gene 1
chr9_-_20871081 5.65 ENSMUST00000177754.9
DNA methyltransferase (cytosine-5) 1
chr7_-_142209755 5.53 ENSMUST00000178921.2
insulin-like growth factor 2
chr19_-_46033353 5.00 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
LIM domain binding 1
chr6_+_41498716 4.96 ENSMUST00000070380.5
protease, serine 2
chr2_-_131001916 4.66 ENSMUST00000103188.10
ENSMUST00000133602.8
ENSMUST00000028800.12
RIKEN cDNA 1700037H04 gene
chr3_+_87989278 4.28 ENSMUST00000071812.11
IQ motif containing GTPase activating protein 3
chr6_-_41423004 4.27 ENSMUST00000095999.7
predicted gene 10334
chr9_-_14292453 4.20 ENSMUST00000167549.2
endonuclease domain containing 1
chr6_-_115014777 3.89 ENSMUST00000174848.8
ENSMUST00000032461.12
TAM41 mitochondrial translocator assembly and maintenance homolog
chr10_+_75399920 3.86 ENSMUST00000141062.8
ENSMUST00000152657.8
gamma-glutamyltransferase 1
chr7_-_24705320 3.83 ENSMUST00000102858.10
ENSMUST00000196684.2
ENSMUST00000080882.11
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr8_-_86091946 3.50 ENSMUST00000034133.14
myosin light chain kinase 3
chr4_-_131802561 3.49 ENSMUST00000105970.8
ENSMUST00000105975.8
erythrocyte membrane protein band 4.1
chr8_-_4829519 3.49 ENSMUST00000022945.9
Shc SH2-domain binding protein 1
chr5_-_138169476 3.38 ENSMUST00000147920.2
minichromosome maintenance complex component 7
chr5_-_44139099 3.32 ENSMUST00000061299.9
fibroblast growth factor binding protein 1
chr9_+_118892497 3.30 ENSMUST00000141185.8
ENSMUST00000126251.8
ENSMUST00000136561.2
villin-like
chr4_-_156340713 3.20 ENSMUST00000219393.2
sterile alpha motif domain containing 11
chr12_-_75678092 3.11 ENSMUST00000238938.2
ribosomal protein, large P2, pseudogene 1
chr8_+_23901506 3.07 ENSMUST00000033952.8
secreted frizzled-related protein 1
chr3_-_113325938 2.88 ENSMUST00000132353.2
amylase 2a1
chr4_-_131802606 2.87 ENSMUST00000146021.8
erythrocyte membrane protein band 4.1
chr11_-_58059293 2.85 ENSMUST00000172035.8
ENSMUST00000035604.13
ENSMUST00000102711.9
gem nuclear organelle associated protein 5
chr6_-_68609426 2.76 ENSMUST00000103328.3
immunoglobulin kappa variable 10-96
chr2_+_124910037 2.73 ENSMUST00000070353.4
solute carrier family 24, member 5
chr1_+_40478787 2.72 ENSMUST00000097772.10
interleukin 1 receptor-like 1
chr2_+_91376650 2.70 ENSMUST00000099716.11
ENSMUST00000046769.16
ENSMUST00000111337.3
cytoskeleton associated protein 5
chr12_-_79054050 2.67 ENSMUST00000056660.13
ENSMUST00000174721.8
transmembrane protein 229B
chr5_-_44139121 2.64 ENSMUST00000199894.2
fibroblast growth factor binding protein 1
chr10_-_128462616 2.63 ENSMUST00000026420.7
ribosomal protein S26
chr7_-_83304698 2.61 ENSMUST00000145610.8
interleukin 16
chr6_+_123239076 2.55 ENSMUST00000032240.4
C-type lectin domain family 4, member d
chr12_+_117807224 2.54 ENSMUST00000021592.16
cell division cycle associated 7 like
chr19_+_5524701 2.53 ENSMUST00000165485.8
ENSMUST00000166253.8
ENSMUST00000167371.8
ENSMUST00000167855.8
ENSMUST00000070118.14
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr9_+_21437440 2.50 ENSMUST00000086361.12
ENSMUST00000173769.3
cDNA sequence AB124611
chr7_-_142253247 2.40 ENSMUST00000105934.8
insulin II
chr11_+_58839716 2.39 ENSMUST00000078267.5
H2B.U histone 2
chr14_+_62529924 2.32 ENSMUST00000166879.8
ribonuclease H2, subunit B
chr5_-_114911548 2.27 ENSMUST00000178440.8
ENSMUST00000043283.14
ENSMUST00000112185.9
ENSMUST00000155908.8
GIT ArfGAP 2
chr11_+_97917520 2.27 ENSMUST00000092425.11
ribosomal protein L19
chrX_+_139857640 2.25 ENSMUST00000112971.2
autophagy related 4A, cysteine peptidase
chr11_+_97917746 2.24 ENSMUST00000017548.7
ribosomal protein L19
chr8_+_85415935 2.24 ENSMUST00000125370.10
ENSMUST00000175784.2
tRNA methyltransferase 1
chr10_-_30076543 2.20 ENSMUST00000099985.6
centromere protein W
chr5_+_136023649 2.19 ENSMUST00000111142.9
ENSMUST00000111145.10
ENSMUST00000111144.8
ENSMUST00000199239.5
ENSMUST00000005072.10
ENSMUST00000130345.2
deltex 2, E3 ubiquitin ligase
chr17_+_28547445 2.14 ENSMUST00000042334.16
ribosomal protein L10A
chr6_+_142244145 2.12 ENSMUST00000041993.3
islet amyloid polypeptide
chr4_-_136329953 2.11 ENSMUST00000105847.8
ENSMUST00000116273.9
lysine (K)-specific demethylase 1A
chr4_+_34893772 2.03 ENSMUST00000029975.10
ENSMUST00000135871.8
ENSMUST00000108130.2
glycoprotein hormones, alpha subunit
chr1_+_160898283 2.03 ENSMUST00000028035.14
ENSMUST00000111620.10
ENSMUST00000111618.8
centromere protein L
chr5_-_151574620 1.97 ENSMUST00000038131.10
replication factor C (activator 1) 3
chr10_-_37014859 1.96 ENSMUST00000092584.6
myristoylated alanine rich protein kinase C substrate
chr19_-_39875192 1.93 ENSMUST00000168838.3
cytochrome P450, family 2, subfamily c, polypeptide 69
chr3_-_88317601 1.92 ENSMUST00000193338.6
ENSMUST00000056370.13
polyamine-modulated factor 1
chrX_+_139857688 1.91 ENSMUST00000239541.1
autophagy related 4A, cysteine peptidase
chr1_-_152262425 1.85 ENSMUST00000015124.15
tRNA splicing endonuclease subunit 15
chr8_+_85415876 1.81 ENSMUST00000109767.9
ENSMUST00000177084.8
ENSMUST00000109768.9
ENSMUST00000152301.9
ENSMUST00000177423.8
tRNA methyltransferase 1
chr1_+_40478926 1.80 ENSMUST00000173514.8
interleukin 1 receptor-like 1
chr3_-_86827640 1.79 ENSMUST00000195561.6
doublecortin-like kinase 2
chr15_+_80017315 1.75 ENSMUST00000023050.9
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr19_-_11582207 1.75 ENSMUST00000025582.11
membrane-spanning 4-domains, subfamily A, member 6D
chr7_+_89814713 1.71 ENSMUST00000207084.2
phosphatidylinositol binding clathrin assembly protein
chr14_-_99337137 1.71 ENSMUST00000042471.11
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
chr10_+_79832313 1.69 ENSMUST00000132517.8
ATP-binding cassette, sub-family A (ABC1), member 7
chr3_-_86827664 1.68 ENSMUST00000194452.2
ENSMUST00000191752.6
doublecortin-like kinase 2
chr9_-_22028370 1.66 ENSMUST00000213233.2
ELF1 homolog, elongation factor 1
chr2_-_85966272 1.66 ENSMUST00000216566.3
ENSMUST00000214364.2
olfactory receptor 1039
chr17_-_56343531 1.63 ENSMUST00000233803.2
SH3-domain GRB2-like 1
chr10_+_97315465 1.62 ENSMUST00000105287.11
decorin
chr19_+_12647803 1.62 ENSMUST00000207341.3
ENSMUST00000208494.3
ENSMUST00000208657.3
olfactory receptor 1442
chr2_+_32253016 1.61 ENSMUST00000132028.8
ENSMUST00000136079.8
CDKN1A interacting zinc finger protein 1
chr2_-_144112700 1.59 ENSMUST00000110030.10
sorting nexin 5
chr17_-_56343625 1.58 ENSMUST00000003268.11
SH3-domain GRB2-like 1
chr17_+_66418525 1.58 ENSMUST00000072383.14
WASH complex subunit 1
chr7_+_45219766 1.57 ENSMUST00000120864.10
branched chain aminotransferase 2, mitochondrial
chr5_-_104261285 1.54 ENSMUST00000199947.2
SPARC-like 1
chr4_-_70328659 1.53 ENSMUST00000144099.8
CDK5 regulatory subunit associated protein 2
chr6_-_122317484 1.52 ENSMUST00000112600.9
polyhomeotic 1
chr6_-_87510200 1.50 ENSMUST00000113637.9
ENSMUST00000071024.7
Rho GTPase activating protein 25
chr9_-_56151334 1.46 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr4_-_135714465 1.44 ENSMUST00000105851.9
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr14_+_19801333 1.44 ENSMUST00000022340.5
nidogen 2
chr14_-_104760051 1.43 ENSMUST00000022716.4
ENSMUST00000228448.2
ENSMUST00000227640.2
ORC ubiquitin ligase 1
chr1_-_88205233 1.43 ENSMUST00000065420.12
ENSMUST00000054674.15
Holliday junction recognition protein
chr2_+_32253692 1.41 ENSMUST00000113331.8
ENSMUST00000113338.9
CDKN1A interacting zinc finger protein 1
chr4_-_106536063 1.40 ENSMUST00000106772.10
ENSMUST00000135676.2
ENSMUST00000026480.13
tetratricopeptide repeat domain 4
chr5_-_114911509 1.39 ENSMUST00000086564.11
GIT ArfGAP 2
chr9_-_22028419 1.39 ENSMUST00000214394.2
ENSMUST00000013966.8
ELF1 homolog, elongation factor 1
chr19_-_7688628 1.36 ENSMUST00000025666.8
solute carrier family 22 (organic anion transporter), member 19
chr14_+_32043944 1.35 ENSMUST00000022480.8
ENSMUST00000228529.2
oxoglutarate dehydrogenase-like
chr1_-_152262339 1.34 ENSMUST00000162371.2
tRNA splicing endonuclease subunit 15
chr10_-_75946790 1.34 ENSMUST00000120757.2
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr10_-_129107354 1.33 ENSMUST00000204573.3
olfactory receptor 777
chr6_-_57827328 1.32 ENSMUST00000203310.3
ENSMUST00000203488.3
vomeronasal 1 receptor 21
chr14_+_51366512 1.32 ENSMUST00000095923.4
ribonuclease, RNase A family, 6
chr2_-_13496624 1.30 ENSMUST00000091436.7
cubilin (intrinsic factor-cobalamin receptor)
chr2_+_32253204 1.28 ENSMUST00000048964.14
ENSMUST00000113332.8
CDKN1A interacting zinc finger protein 1
chr6_+_122490534 1.27 ENSMUST00000032210.14
ENSMUST00000148517.8
microfibrillar associated protein 5
chr6_-_69282389 1.26 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr11_+_102080446 1.25 ENSMUST00000070334.10
glucose 6 phosphatase, catalytic, 3
chr13_+_21995906 1.24 ENSMUST00000104941.4
H4 clustered histone 17
chr3_-_72875187 1.22 ENSMUST00000167334.8
sucrase isomaltase (alpha-glucosidase)
chr9_+_19828161 1.22 ENSMUST00000217347.2
ENSMUST00000057596.10
olfactory receptor 77
chr5_-_114911432 1.20 ENSMUST00000112183.8
GIT ArfGAP 2
chr11_+_102080489 1.20 ENSMUST00000078975.8
glucose 6 phosphatase, catalytic, 3
chr14_+_119025306 1.20 ENSMUST00000047761.13
ENSMUST00000071546.14
claudin 10
chr19_+_34078333 1.19 ENSMUST00000025685.8
lipase, family member M
chr17_+_66418598 1.18 ENSMUST00000116556.4
ENSMUST00000233354.2
WASH complex subunit 1
chr9_+_65368207 1.15 ENSMUST00000034955.8
ENSMUST00000213957.2
SPG21, maspardin
chr3_-_105839980 1.15 ENSMUST00000098758.5
RIKEN cDNA I830077J02 gene
chr12_-_69939762 1.14 ENSMUST00000110567.8
ENSMUST00000171211.8
mitogen-activated protein kinase kinase kinase kinase 5
chr5_-_116162415 1.13 ENSMUST00000031486.14
ENSMUST00000111999.8
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr4_+_19818718 1.13 ENSMUST00000035890.8
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr2_-_73284262 1.12 ENSMUST00000102679.8
WAS/WASL interacting protein family, member 1
chr7_+_128346655 1.12 ENSMUST00000042942.10
Sec23 interacting protein
chr2_+_22785534 1.11 ENSMUST00000053729.14
prenyl (solanesyl) diphosphate synthase, subunit 1
chr2_-_29677634 1.08 ENSMUST00000177467.8
ENSMUST00000113807.10
TruB pseudouridine (psi) synthase family member 2
chr7_+_101545547 1.06 ENSMUST00000035395.14
ENSMUST00000106973.8
ENSMUST00000144207.9
anaphase promoting complex C subunit 15
chr7_+_126376099 1.06 ENSMUST00000038614.12
ENSMUST00000170882.8
ENSMUST00000106359.2
ENSMUST00000106357.8
ENSMUST00000145762.8
yippee like 3
chr6_-_87312743 1.06 ENSMUST00000042025.12
ENSMUST00000205033.2
anthrax toxin receptor 1
chr12_-_113790741 1.06 ENSMUST00000103457.3
ENSMUST00000192877.2
immunoglobulin heavy variable 5-15
chr11_-_51497665 1.05 ENSMUST00000074669.10
ENSMUST00000101249.9
ENSMUST00000109103.4
heterogeneous nuclear ribonucleoprotein A/B
chr15_-_77840856 1.03 ENSMUST00000117725.2
ENSMUST00000016696.13
FAD-dependent oxidoreductase domain containing 2
chr19_-_32173824 1.02 ENSMUST00000151822.2
sphingomyelin synthase 1
chr19_-_24178000 1.02 ENSMUST00000233658.3
tight junction protein 2
chr2_+_85838122 1.01 ENSMUST00000062166.2
olfactory receptor 1032
chr12_-_80690573 1.01 ENSMUST00000166931.2
ENSMUST00000218364.2
ERH mRNA splicing and mitosis factor
chr10_+_85858050 0.99 ENSMUST00000120344.8
ENSMUST00000117597.2
F-box protein 7
chr8_+_31640332 0.98 ENSMUST00000209851.2
ENSMUST00000098842.3
ENSMUST00000210129.2
TELO2 interacting protein 2
chr13_+_51562675 0.98 ENSMUST00000087978.5
sphingosine-1-phosphate receptor 3
chr7_+_45271229 0.97 ENSMUST00000033100.5
izumo sperm-egg fusion 1
chr2_-_88590813 0.96 ENSMUST00000124021.3
olfactory receptor 1199
chr2_+_24257576 0.96 ENSMUST00000140547.2
ENSMUST00000102942.8
pleckstrin and Sec7 domain containing 4
chr7_-_30259025 0.95 ENSMUST00000043975.11
ENSMUST00000156241.2
lin-37 homolog (C. elegans)
chr1_-_88205185 0.95 ENSMUST00000147393.2
Holliday junction recognition protein
chr15_-_82678490 0.95 ENSMUST00000006094.6
cytochrome P450, family 2, subfamily d, polypeptide 26
chr8_+_107757847 0.94 ENSMUST00000034388.10
vacuolar protein sorting 4A
chr5_+_136145485 0.93 ENSMUST00000111127.8
ENSMUST00000041366.14
ENSMUST00000111129.2
polymerase (RNA) II (DNA directed) polypeptide J
chr14_-_69945022 0.93 ENSMUST00000118374.8
R3H domain and coiled-coil containing 1
chrX_+_20529137 0.93 ENSMUST00000001989.9
ubiquitin-like modifier activating enzyme 1
chr17_-_57338468 0.93 ENSMUST00000007814.10
ENSMUST00000233480.2
KH-type splicing regulatory protein
chr15_-_79658608 0.92 ENSMUST00000229644.2
ENSMUST00000023055.8
dynein, axonemal, light chain 4
chr14_-_54923517 0.92 ENSMUST00000125265.2
apoptotic chromatin condensation inducer 1
chr4_-_43710231 0.92 ENSMUST00000217544.2
ENSMUST00000107862.3
olfactory receptor 71
chr3_-_66204228 0.91 ENSMUST00000029419.8
ventricular zone expressed PH domain-containing 1
chr1_-_127605660 0.91 ENSMUST00000160616.8
transmembrane protein 163
chr13_+_76727787 0.91 ENSMUST00000126960.8
ENSMUST00000109583.9
multiple C2 domains, transmembrane 1
chr12_-_114710326 0.89 ENSMUST00000103507.2
immunoglobulin heavy variable 1-22
chr1_+_135768595 0.89 ENSMUST00000112087.9
ENSMUST00000178854.8
ENSMUST00000027671.12
ENSMUST00000179863.8
ENSMUST00000112085.9
ENSMUST00000112086.3
troponin T2, cardiac
chrX_-_105264751 0.87 ENSMUST00000113495.9
TATA-box binding protein associated factor 9B
chr6_-_118456198 0.87 ENSMUST00000161170.2
zinc finger protein 9
chr12_-_46863726 0.85 ENSMUST00000219330.2
NOVA alternative splicing regulator 1
chr14_-_69944942 0.85 ENSMUST00000121142.4
R3H domain and coiled-coil containing 1
chr11_+_62442502 0.84 ENSMUST00000136938.2
ubiquitin B
chr7_-_110673269 0.82 ENSMUST00000163014.2
eukaryotic translation initiation factor 4, gamma 2
chr2_-_126342551 0.82 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr6_-_30936013 0.81 ENSMUST00000101589.5
Kruppel-like factor 14
chr2_+_65451100 0.78 ENSMUST00000144254.6
ENSMUST00000028377.14
sodium channel, voltage-gated, type II, alpha
chr9_-_123507937 0.78 ENSMUST00000040960.13
solute carrier family 6 (neurotransmitter transporter), member 20A
chr3_+_32762656 0.78 ENSMUST00000029214.14
actin-like 6A
chr8_+_22224506 0.78 ENSMUST00000080533.6
defensin, alpha, 24
chr7_-_30259253 0.78 ENSMUST00000108164.8
lin-37 homolog (C. elegans)
chr9_+_123902143 0.78 ENSMUST00000168841.3
ENSMUST00000055918.7
chemokine (C-C motif) receptor 2
chr8_-_70963202 0.77 ENSMUST00000125184.8
ubiquitin A-52 residue ribosomal protein fusion product 1
chr11_-_99134885 0.77 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chr9_-_89586960 0.77 ENSMUST00000058488.9
transmembrane p24 trafficking protein 3
chr5_-_118293443 0.77 ENSMUST00000049474.9
F-box and WD-40 domain protein 8
chr6_+_68279392 0.77 ENSMUST00000103322.3
immunoglobulin kappa variable 2-109
chr12_+_38833454 0.75 ENSMUST00000161980.8
ENSMUST00000160701.8
ets variant 1
chrX_-_9123138 0.75 ENSMUST00000115553.3
predicted gene 14862
chr2_-_88519531 0.74 ENSMUST00000213545.2
olfactory receptor 1195
chr13_-_103911092 0.74 ENSMUST00000074616.7
splicing regulatory glutamine/lysine-rich protein 1
chr2_+_87696836 0.72 ENSMUST00000213308.3
olfactory receptor 1152
chr2_-_111843053 0.72 ENSMUST00000213559.3
olfactory receptor 1310
chr18_+_37898633 0.72 ENSMUST00000044851.8
protocadherin gamma subfamily A, 12
chr7_+_101546059 0.71 ENSMUST00000143835.8
anaphase promoting complex C subunit 15
chr5_+_3593811 0.71 ENSMUST00000197082.5
ENSMUST00000115527.8
family with sequence similarity 133, member B
chr6_-_68887957 0.71 ENSMUST00000200454.2
immunoglobulin kappa variable 4-86
chr11_+_106107752 0.70 ENSMUST00000021046.6
DEAD box helicase 42
chr9_+_98873831 0.69 ENSMUST00000185472.2
Fas apoptotic inhibitory molecule
chr15_-_79658584 0.69 ENSMUST00000069877.12
dynein, axonemal, light chain 4
chr2_-_86109346 0.67 ENSMUST00000217294.2
ENSMUST00000217245.2
ENSMUST00000216432.2
olfactory receptor 1051
chr4_-_147894245 0.67 ENSMUST00000105734.10
ENSMUST00000176201.2
zinc finger protein 984
predicted gene 20707
chr8_-_70962972 0.66 ENSMUST00000140679.8
ENSMUST00000129909.8
ENSMUST00000081940.11
ubiquitin A-52 residue ribosomal protein fusion product 1
chr1_+_134333720 0.66 ENSMUST00000173908.8
cytochrome b5 reductase 1
chr3_+_90200470 0.66 ENSMUST00000199754.5
GATA zinc finger domain containing 2B
chr7_-_103094646 0.66 ENSMUST00000215417.2
olfactory receptor 605

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.2 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
2.3 9.3 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
1.7 5.0 GO:0043973 histone H3-K4 acetylation(GO:0043973)
1.6 6.6 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
1.6 19.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.4 5.6 GO:0090116 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.3 4.0 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
1.1 4.3 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
1.0 3.1 GO:2000040 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.8 6.5 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.8 6.4 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.8 2.4 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
0.7 2.7 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.7 6.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.6 6.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.6 4.2 GO:0051697 protein delipidation(GO:0051697)
0.6 3.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.6 1.7 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.6 7.2 GO:0006020 inositol metabolic process(GO:0006020)
0.5 2.1 GO:0046098 guanine metabolic process(GO:0046098)
0.5 1.6 GO:0006550 isoleucine catabolic process(GO:0006550)
0.5 3.9 GO:1901748 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.5 5.5 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.5 2.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 7.5 GO:0043129 surfactant homeostasis(GO:0043129)
0.4 1.7 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.4 2.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.4 2.8 GO:2000911 positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911)
0.4 4.5 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.4 1.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.4 3.9 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.4 6.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 2.5 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.3 0.9 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.3 1.7 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3 1.9 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.3 3.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.3 2.1 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3 0.8 GO:1902567 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.3 3.8 GO:0036376 sodium ion export from cell(GO:0036376)
0.2 2.4 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 3.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 5.0 GO:0031000 response to caffeine(GO:0031000)
0.2 4.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 2.0 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 1.3 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.4 GO:0061346 dichotomous subdivision of terminal units involved in lung branching(GO:0060448) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.2 1.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 0.6 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.2 1.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 1.4 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.2 1.0 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 1.6 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 3.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.0 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 2.0 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.1 0.4 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1 2.6 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.5 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.9 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 4.9 GO:0048266 behavioral response to pain(GO:0048266)
0.1 1.0 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 2.2 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 2.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 1.1 GO:0035878 nail development(GO:0035878)
0.1 0.5 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.8 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 2.8 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 1.3 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.8 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.3 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.2 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 1.0 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.1 2.2 GO:0097435 fibril organization(GO:0097435)
0.1 0.9 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.8 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 2.0 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.1 2.1 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 2.1 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 2.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) negative regulation of neutrophil activation(GO:1902564)
0.1 8.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.2 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.1 7.7 GO:0007586 digestion(GO:0007586)
0.1 7.0 GO:0042100 B cell proliferation(GO:0042100)
0.1 1.1 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.5 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 2.6 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 1.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 1.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.6 GO:0006907 pinocytosis(GO:0006907)
0.0 3.3 GO:0051693 actin filament capping(GO:0051693)
0.0 0.7 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726) cellular response to hyperoxia(GO:0071455)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.6 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 3.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.8 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 1.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.0 GO:0060003 copper ion export(GO:0060003)
0.0 0.1 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.6 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 2.9 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.2 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.8 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.2 19.5 GO:0042555 MCM complex(GO:0042555)
1.0 16.2 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.6 7.5 GO:0097208 alveolar lamellar body(GO:0097208)
0.6 6.2 GO:0019815 B cell receptor complex(GO:0019815)
0.4 2.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 1.9 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.3 3.8 GO:0044326 dendritic spine neck(GO:0044326)
0.3 2.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 2.0 GO:0042585 germinal vesicle(GO:0042585)
0.3 1.3 GO:0043202 lysosomal lumen(GO:0043202)
0.2 1.0 GO:1990037 Lewy body core(GO:1990037)
0.2 1.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 2.8 GO:0032797 SMN complex(GO:0032797)
0.2 1.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313) tubular endosome(GO:0097422)
0.2 2.8 GO:0071203 WASH complex(GO:0071203)
0.2 1.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 5.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 1.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 5.8 GO:0097228 sperm principal piece(GO:0097228)
0.1 2.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.8 GO:1990393 3M complex(GO:1990393)
0.1 1.5 GO:0001739 sex chromatin(GO:0001739)
0.1 4.8 GO:0035371 microtubule plus-end(GO:0035371)
0.1 8.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0061574 ASAP complex(GO:0061574)
0.1 2.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 1.0 GO:0034709 methylosome(GO:0034709)
0.1 2.4 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.6 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124)
0.1 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.3 GO:0070820 tertiary granule(GO:0070820)
0.1 1.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 3.0 GO:0099738 cell cortex region(GO:0099738)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 1.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 2.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 4.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.0 2.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 7.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.8 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.2 GO:0030286 dynein complex(GO:0030286)
0.0 1.3 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 10.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 4.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 2.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.1 GO:0019814 immunoglobulin complex(GO:0019814)
0.0 5.8 GO:0016607 nuclear speck(GO:0016607)
0.0 5.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.5 4.5 GO:0002113 interleukin-33 binding(GO:0002113)
1.3 3.9 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
1.1 4.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.9 2.8 GO:0030622 U4atac snRNA binding(GO:0030622)
0.8 4.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.8 6.4 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.8 3.2 GO:0032093 SAM domain binding(GO:0032093)
0.6 2.4 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.6 4.3 GO:0032027 myosin light chain binding(GO:0032027)
0.6 1.7 GO:0034188 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.6 2.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.6 7.2 GO:0008199 ferric iron binding(GO:0008199)
0.5 3.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.5 5.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.5 2.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 19.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 3.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 2.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3 5.0 GO:0030274 LIM domain binding(GO:0030274)
0.3 2.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 3.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.3 3.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 1.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.3 1.1 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.3 3.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.3 0.8 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.2 8.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 7.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 8.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 1.6 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.3 GO:0030492 hemoglobin binding(GO:0030492)
0.2 2.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 11.9 GO:0004601 peroxidase activity(GO:0004601)
0.2 1.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 2.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 6.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 6.7 GO:0005158 insulin receptor binding(GO:0005158)
0.1 3.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.9 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.4 GO:0003696 satellite DNA binding(GO:0003696)
0.1 1.4 GO:0019534 toxin transporter activity(GO:0019534)
0.1 1.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 3.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.8 GO:0034452 dynactin binding(GO:0034452)
0.1 10.3 GO:0005179 hormone activity(GO:0005179)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 4.3 GO:0030332 cyclin binding(GO:0030332)
0.1 0.8 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.1 15.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 3.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 1.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 4.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 3.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 4.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0035478 chylomicron binding(GO:0035478)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.8 GO:0070330 aromatase activity(GO:0070330)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 3.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 5.8 GO:0005549 odorant binding(GO:0005549)
0.0 5.9 GO:0001047 core promoter binding(GO:0001047)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.3 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 2.4 GO:0004519 endonuclease activity(GO:0004519)
0.0 6.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.0 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.1 GO:0004620 phospholipase activity(GO:0004620)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 21.9 PID ATR PATHWAY ATR signaling pathway
0.4 6.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 16.2 PID IL23 PATHWAY IL23-mediated signaling events
0.2 9.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 6.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 6.7 PID IGF1 PATHWAY IGF1 pathway
0.1 8.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.7 PID AURORA A PATHWAY Aurora A signaling
0.1 6.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 3.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.5 PID BCR 5PATHWAY BCR signaling pathway
0.1 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 4.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 4.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 1.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 10.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 7.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 3.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 19.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.1 6.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.8 9.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.5 6.8 REACTOME DEFENSINS Genes involved in Defensins
0.3 3.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3 6.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.3 5.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.0 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 1.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 2.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 8.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 6.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.0 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 2.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 4.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 9.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 6.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 3.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade