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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Arid5a

Z-value: 0.84

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Transcription factors associated with Arid5a

Gene Symbol Gene ID Gene Info
Arid5a
ENSMUSG00000037447.17 Arid5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Arid5amm39_v1_chr1_+_36346824_36346850-0.733.9e-07Click!

Activity profile of Arid5a motif

Sorted Z-values of Arid5a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid5a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_87074380 6.03 ENSMUST00000031183.3
Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
chr2_+_58645189 5.72 ENSMUST00000102755.4
ENSMUST00000230627.2
ENSMUST00000229923.2
Upp2
uridine phosphorylase 2
chr2_+_58644922 5.09 ENSMUST00000059102.13
Upp2
uridine phosphorylase 2
chr10_-_115198093 3.82 ENSMUST00000219890.2
ENSMUST00000218731.2
ENSMUST00000217887.2
ENSMUST00000092170.7
Tmem19
transmembrane protein 19
chr7_-_105249308 3.16 ENSMUST00000210531.2
ENSMUST00000033185.10
Hpx
hemopexin
chr10_-_115197775 2.95 ENSMUST00000217848.2
Tmem19
transmembrane protein 19
chr15_-_55421144 1.02 ENSMUST00000172387.8
Mrpl13
mitochondrial ribosomal protein L13
chr14_+_58313964 0.73 ENSMUST00000166770.2
Fgf9
fibroblast growth factor 9
chr3_+_122298308 0.65 ENSMUST00000199358.2
Bcar3
breast cancer anti-estrogen resistance 3
chr1_-_171885140 0.62 ENSMUST00000059794.4
Nhlh1
nescient helix loop helix 1
chr17_-_35265702 0.60 ENSMUST00000097338.11
Msh5
mutS homolog 5
chrM_+_8603 0.59 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr2_+_105505823 0.46 ENSMUST00000167211.9
ENSMUST00000111083.10
Pax6
paired box 6
chr11_-_58425662 0.39 ENSMUST00000213188.3
Olfr330
olfactory receptor 330
chr2_+_61876956 0.39 ENSMUST00000112480.3
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chrM_+_7779 0.35 ENSMUST00000082408.1
mt-Atp6
mitochondrially encoded ATP synthase 6
chrM_+_7758 0.32 ENSMUST00000082407.1
mt-Atp8
mitochondrially encoded ATP synthase 8
chr2_+_61876923 0.25 ENSMUST00000054484.15
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr10_-_129530155 0.19 ENSMUST00000204641.3
Olfr803
olfactory receptor 803
chr10_+_52267702 0.18 ENSMUST00000067085.7
Nepn
nephrocan
chr3_-_146487102 0.17 ENSMUST00000005164.12
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr17_-_37627945 0.12 ENSMUST00000217590.2
Olfr102
olfactory receptor 102
chrX_-_156198282 0.11 ENSMUST00000079945.11
ENSMUST00000138396.3
Phex
phosphate regulating endopeptidase homolog, X-linked
chr16_-_58583539 0.08 ENSMUST00000214139.2
Olfr172
olfactory receptor 172
chr2_-_79959802 0.06 ENSMUST00000102653.8
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr4_+_43384320 0.05 ENSMUST00000136360.2
Rusc2
RUN and SH3 domain containing 2
chr10_+_69369854 0.03 ENSMUST00000182557.8
Ank3
ankyrin 3, epithelial
chr2_+_61876806 0.01 ENSMUST00000102735.10
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0018879 biphenyl metabolic process(GO:0018879)
0.5 3.2 GO:0060335 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) heme transport(GO:0015886) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.5 GO:1904937 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.1 10.9 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.7 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.6 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.8 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.6 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 1.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 10.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.5 3.2 GO:0015232 heme transporter activity(GO:0015232)
0.1 6.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680) co-SMAD binding(GO:0070410)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination