Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Atf4

Z-value: 2.09

Motif logo

logo of

Transcription factors associated with Atf4

Gene Symbol Gene ID Gene Info
Atf4
ENSMUSG00000042406.9 Atf4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atf4mm39_v1_chr15_+_80139371_801393860.633.8e-05Click!

Activity profile of Atf4 motif

Sorted Z-values of Atf4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr16_-_36188086 13.96 ENSMUST00000096089.3
Cstdc5
cystatin domain containing 5
chr5_-_148336711 12.22 ENSMUST00000048116.15
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr14_-_56339915 11.95 ENSMUST00000015583.2
Ctsg
cathepsin G
chr16_+_36097505 11.18 ENSMUST00000042097.11
Stfa1
stefin A1
chr14_-_69522431 9.97 ENSMUST00000183882.2
ENSMUST00000037064.5
Slc25a37
solute carrier family 25, member 37
chr9_-_44255456 9.63 ENSMUST00000077353.15
Hmbs
hydroxymethylbilane synthase
chr7_+_78563964 9.38 ENSMUST00000120331.4
Isg20
interferon-stimulated protein
chr4_+_43957677 9.21 ENSMUST00000107855.2
Glipr2
GLI pathogenesis-related 2
chr5_-_129856237 9.20 ENSMUST00000118268.9
Psph
phosphoserine phosphatase
chr5_-_129856267 9.13 ENSMUST00000201394.4
Psph
phosphoserine phosphatase
chr11_-_120534469 7.36 ENSMUST00000141254.8
ENSMUST00000170556.8
ENSMUST00000151876.8
ENSMUST00000026133.15
ENSMUST00000139706.2
Pycr1
pyrroline-5-carboxylate reductase 1
chr14_+_55777807 6.94 ENSMUST00000226352.2
Pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr6_-_83294526 6.41 ENSMUST00000005810.9
Mthfd2
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr7_+_44117444 6.13 ENSMUST00000206887.2
ENSMUST00000117324.8
ENSMUST00000120852.8
ENSMUST00000134398.3
ENSMUST00000118628.8
Josd2
Josephin domain containing 2
chr4_+_46450892 5.90 ENSMUST00000102926.5
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr4_+_117692583 5.74 ENSMUST00000169885.8
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr7_+_44117511 5.53 ENSMUST00000121922.3
ENSMUST00000208117.2
Josd2
Josephin domain containing 2
chr19_-_40576897 5.46 ENSMUST00000025979.13
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr7_+_44117475 5.36 ENSMUST00000118493.8
Josd2
Josephin domain containing 2
chr19_-_40576782 5.34 ENSMUST00000176939.8
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr7_+_44117404 5.25 ENSMUST00000035844.11
Josd2
Josephin domain containing 2
chr16_-_36154692 5.04 ENSMUST00000114850.3
Cstdc6
cystatin domain containing 6
chr4_+_126915104 4.88 ENSMUST00000030623.8
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr2_+_148640705 4.79 ENSMUST00000028931.10
ENSMUST00000109947.2
Cst8
cystatin 8 (cystatin-related epididymal spermatogenic)
chr14_-_54655079 4.43 ENSMUST00000226753.2
ENSMUST00000197440.5
Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr19_-_40576817 4.39 ENSMUST00000175932.2
ENSMUST00000176955.8
ENSMUST00000149476.3
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr12_+_105996961 4.08 ENSMUST00000220629.2
Vrk1
vaccinia related kinase 1
chr5_-_148336574 3.88 ENSMUST00000202457.4
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_+_55014973 3.47 ENSMUST00000003572.10
Gars
glycyl-tRNA synthetase
chr7_-_3551003 3.45 ENSMUST00000065703.9
ENSMUST00000203020.3
ENSMUST00000203821.3
Tarm1
T cell-interacting, activating receptor on myeloid cells 1
chr3_+_88523440 3.35 ENSMUST00000177498.8
ENSMUST00000176500.8
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr14_-_54655237 3.32 ENSMUST00000195999.2
Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr19_+_53128901 3.29 ENSMUST00000235754.2
ENSMUST00000237301.2
ENSMUST00000238130.2
Add3
adducin 3 (gamma)
chr19_-_8690330 3.28 ENSMUST00000206598.2
Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr12_+_73333641 3.00 ENSMUST00000153941.8
ENSMUST00000122920.8
ENSMUST00000101313.4
Slc38a6
solute carrier family 38, member 6
chr4_+_129083553 2.98 ENSMUST00000106054.4
Yars
tyrosyl-tRNA synthetase
chr2_-_3513783 2.93 ENSMUST00000124331.8
ENSMUST00000140494.2
ENSMUST00000027961.12
Gm45902
Hspa14
predicted gene 45902
heat shock protein 14
chr6_-_16898440 2.82 ENSMUST00000031533.11
Tfec
transcription factor EC
chr11_-_20282684 2.68 ENSMUST00000004634.7
ENSMUST00000109594.8
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr12_+_85645801 2.64 ENSMUST00000177587.9
Jdp2
Jun dimerization protein 2
chr9_-_45896663 2.58 ENSMUST00000214179.2
Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr13_+_49835576 2.49 ENSMUST00000165316.8
ENSMUST00000047363.14
Iars
isoleucine-tRNA synthetase
chr12_+_85646162 2.37 ENSMUST00000050687.14
Jdp2
Jun dimerization protein 2
chr19_+_53128861 2.35 ENSMUST00000111741.10
Add3
adducin 3 (gamma)
chr18_-_42395207 2.34 ENSMUST00000097590.5
Lars
leucyl-tRNA synthetase
chr4_+_124635635 2.32 ENSMUST00000094782.10
ENSMUST00000153837.8
ENSMUST00000154229.2
Inpp5b
inositol polyphosphate-5-phosphatase B
chr2_+_172235702 2.24 ENSMUST00000099061.9
ENSMUST00000103073.9
Cass4
Cas scaffolding protein family member 4
chr3_+_88523730 2.24 ENSMUST00000175779.8
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr11_+_100211363 2.20 ENSMUST00000152521.2
Eif1
eukaryotic translation initiation factor 1
chr15_-_76594723 2.14 ENSMUST00000036852.9
Recql4
RecQ protein-like 4
chr10_+_127126643 2.11 ENSMUST00000026475.15
ENSMUST00000139091.2
ENSMUST00000230446.2
Ddit3
Ddit3
DNA-damage inducible transcript 3
DNA-damage inducible transcript 3
chr2_+_172235820 2.10 ENSMUST00000109136.3
ENSMUST00000228775.2
Cass4
Cas scaffolding protein family member 4
chr18_-_64649497 2.05 ENSMUST00000237351.2
ENSMUST00000236186.2
ENSMUST00000235325.2
Nars
asparaginyl-tRNA synthetase
chr7_-_143153785 2.03 ENSMUST00000105909.4
ENSMUST00000010899.14
Cars
cysteinyl-tRNA synthetase
chr18_-_64649620 2.00 ENSMUST00000025483.11
ENSMUST00000237400.2
Nars
asparaginyl-tRNA synthetase
chr7_+_125202653 1.96 ENSMUST00000206103.2
ENSMUST00000033000.8
Il21r
interleukin 21 receptor
chr18_-_42395131 1.95 ENSMUST00000236102.2
Lars
leucyl-tRNA synthetase
chr3_-_105839980 1.86 ENSMUST00000098758.5
I830077J02Rik
RIKEN cDNA I830077J02 gene
chr15_-_76594625 1.86 ENSMUST00000230544.2
Recql4
RecQ protein-like 4
chr13_+_49835667 1.69 ENSMUST00000172254.3
Iars
isoleucine-tRNA synthetase
chr6_-_129484070 1.56 ENSMUST00000183258.8
ENSMUST00000182784.4
ENSMUST00000032265.13
ENSMUST00000162815.2
Olr1
oxidized low density lipoprotein (lectin-like) receptor 1
chr3_-_96170627 1.56 ENSMUST00000171473.3
H4c14
H4 clustered histone 14
chr1_-_78465479 1.47 ENSMUST00000190441.2
ENSMUST00000170217.8
ENSMUST00000188247.7
ENSMUST00000068333.14
Farsb
phenylalanyl-tRNA synthetase, beta subunit
chr5_-_31337193 1.46 ENSMUST00000201428.2
ENSMUST00000201468.4
ENSMUST00000101411.6
Gtf3c2
Gm29609
general transcription factor IIIC, polypeptide 2, beta
predicted gene 29609
chr2_+_163837423 1.40 ENSMUST00000131288.2
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr7_-_126101484 1.33 ENSMUST00000166682.9
Atxn2l
ataxin 2-like
chr8_-_106427696 1.31 ENSMUST00000042608.8
Acd
adrenocortical dysplasia
chr2_+_87853118 1.22 ENSMUST00000214438.2
Olfr1161
olfactory receptor 1161
chr11_-_98291278 1.16 ENSMUST00000090827.12
Pgap3
post-GPI attachment to proteins 3
chr12_-_108859123 1.16 ENSMUST00000161154.2
ENSMUST00000161410.8
Wars
tryptophanyl-tRNA synthetase
chr7_-_126101555 1.16 ENSMUST00000167759.8
Atxn2l
ataxin 2-like
chr7_-_126101245 1.16 ENSMUST00000179818.3
Atxn2l
ataxin 2-like
chr15_+_82031382 1.14 ENSMUST00000023100.8
ENSMUST00000229336.2
Srebf2
sterol regulatory element binding factor 2
chr11_+_67061908 0.98 ENSMUST00000018641.8
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr11_+_67061837 0.96 ENSMUST00000170159.8
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr14_-_36857083 0.94 ENSMUST00000042564.17
Ghitm
growth hormone inducible transmembrane protein
chr5_-_31337453 0.92 ENSMUST00000202639.4
ENSMUST00000088010.12
Gtf3c2
general transcription factor IIIC, polypeptide 2, beta
chr14_-_32407203 0.91 ENSMUST00000096038.4
3425401B19Rik
RIKEN cDNA 3425401B19 gene
chr3_-_59038031 0.83 ENSMUST00000091112.6
ENSMUST00000065220.13
P2ry14
purinergic receptor P2Y, G-protein coupled, 14
chr3_-_89905927 0.83 ENSMUST00000197725.5
ENSMUST00000197767.5
ENSMUST00000197786.5
ENSMUST00000079724.9
Hax1
HCLS1 associated X-1
chr4_+_42735912 0.83 ENSMUST00000107984.2
4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr10_+_101994841 0.80 ENSMUST00000020039.13
Mgat4c
MGAT4 family, member C
chr1_+_156666485 0.76 ENSMUST00000111720.2
Angptl1
angiopoietin-like 1
chr7_-_126224848 0.70 ENSMUST00000032961.4
Nupr1
nuclear protein transcription regulator 1
chr9_-_15023396 0.69 ENSMUST00000159985.2
Hephl1
hephaestin-like 1
chr3_-_123029745 0.69 ENSMUST00000106426.8
Synpo2
synaptopodin 2
chr3_-_123029782 0.68 ENSMUST00000106427.8
ENSMUST00000198584.2
Synpo2
synaptopodin 2
chr5_+_145077172 0.67 ENSMUST00000162594.8
ENSMUST00000162308.8
ENSMUST00000159018.8
ENSMUST00000160075.2
Bud31
BUD31 homolog
chr11_-_98291220 0.62 ENSMUST00000128897.2
Pgap3
post-GPI attachment to proteins 3
chr14_-_50538979 0.61 ENSMUST00000216195.2
ENSMUST00000214372.2
ENSMUST00000214756.2
Olfr733
olfactory receptor 733
chr11_-_115167775 0.57 ENSMUST00000021078.3
Fdxr
ferredoxin reductase
chr13_-_101829132 0.56 ENSMUST00000035532.13
Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
chr3_-_127202635 0.52 ENSMUST00000182959.8
Ank2
ankyrin 2, brain
chr17_+_48769383 0.50 ENSMUST00000162132.8
Unc5cl
unc-5 family C-terminal like
chr6_+_65019558 0.48 ENSMUST00000204801.3
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr3_-_89905547 0.45 ENSMUST00000199740.2
ENSMUST00000198782.2
Hax1
HCLS1 associated X-1
chr3_-_59038539 0.44 ENSMUST00000198838.2
P2ry14
purinergic receptor P2Y, G-protein coupled, 14
chr3_-_127202693 0.42 ENSMUST00000182078.9
Ank2
ankyrin 2, brain
chr15_+_99590098 0.41 ENSMUST00000228185.2
Asic1
acid-sensing (proton-gated) ion channel 1
chr14_-_55108384 0.39 ENSMUST00000146642.2
Homez
homeodomain leucine zipper-encoding gene
chr14_-_50521663 0.38 ENSMUST00000213701.2
Olfr732
olfactory receptor 732
chr7_-_126165530 0.38 ENSMUST00000180459.3
ENSMUST00000032992.7
Eif3c
eukaryotic translation initiation factor 3, subunit C
chr4_+_138606671 0.37 ENSMUST00000105804.2
Pla2g2e
phospholipase A2, group IIE
chr4_+_42293921 0.37 ENSMUST00000238203.2
Gm21953
predicted gene, 21953
chr2_+_118877610 0.37 ENSMUST00000153300.8
ENSMUST00000028799.12
Knl1
kinetochore scaffold 1
chr4_+_42735545 0.36 ENSMUST00000068158.10
4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr10_+_101994719 0.34 ENSMUST00000138522.8
ENSMUST00000163753.8
ENSMUST00000138016.8
Mgat4c
MGAT4 family, member C
chr4_-_118036827 0.34 ENSMUST00000097911.9
Kdm4a
lysine (K)-specific demethylase 4A
chr3_-_127202663 0.33 ENSMUST00000182008.8
ENSMUST00000182547.8
Ank2
ankyrin 2, brain
chr3_+_93227047 0.32 ENSMUST00000090856.10
ENSMUST00000093774.4
Hrnr
hornerin
chr19_-_50667079 0.31 ENSMUST00000209413.2
ENSMUST00000072685.13
ENSMUST00000164039.9
Sorcs1
sortilin-related VPS10 domain containing receptor 1
chr1_-_190915441 0.29 ENSMUST00000027941.14
Atf3
activating transcription factor 3
chr11_-_79418500 0.29 ENSMUST00000154415.2
Evi2a
ecotropic viral integration site 2a
chr5_-_145077048 0.27 ENSMUST00000031627.9
Pdap1
PDGFA associated protein 1
chr3_-_59038160 0.26 ENSMUST00000197841.2
P2ry14
purinergic receptor P2Y, G-protein coupled, 14
chr6_+_65019574 0.26 ENSMUST00000031984.9
ENSMUST00000205118.3
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_175526152 0.26 ENSMUST00000094288.10
ENSMUST00000171939.8
Wdr64
WD repeat domain 64
chr13_-_101829070 0.23 ENSMUST00000187009.7
Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
chrX_+_102465616 0.22 ENSMUST00000182089.2
Gm26992
predicted gene, 26992
chr2_-_65955338 0.22 ENSMUST00000028378.4
Galnt3
polypeptide N-acetylgalactosaminyltransferase 3
chrX_+_163221035 0.21 ENSMUST00000033755.6
Asb11
ankyrin repeat and SOCS box-containing 11
chr9_+_32283779 0.20 ENSMUST00000047334.10
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
chr8_-_123202774 0.17 ENSMUST00000014614.4
Rnf166
ring finger protein 166
chr2_-_89423470 0.14 ENSMUST00000217254.2
ENSMUST00000217192.2
ENSMUST00000213221.2
Olfr1246
olfactory receptor 1246
chr10_-_127358300 0.13 ENSMUST00000026470.6
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr5_+_93241287 0.13 ENSMUST00000074733.11
ENSMUST00000201700.4
ENSMUST00000202196.4
ENSMUST00000202308.4
Septin11
septin 11
chr16_-_29363671 0.08 ENSMUST00000039090.9
Atp13a4
ATPase type 13A4
chr10_-_127358231 0.06 ENSMUST00000219239.2
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_-_92412835 0.05 ENSMUST00000214928.3
Olfr1416
olfactory receptor 1416
chr13_-_118523760 0.02 ENSMUST00000022245.10
Mrps30
mitochondrial ribosomal protein S30

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.2 GO:0006592 ornithine biosynthetic process(GO:0006592)
3.2 9.6 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
2.3 18.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.9 5.7 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.6 9.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.5 7.4 GO:0006561 proline biosynthetic process(GO:0006561)
1.4 4.3 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
1.4 4.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
1.2 11.9 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
1.2 6.9 GO:0006116 NADH oxidation(GO:0006116)
1.0 4.1 GO:0072355 histone H3-T3 phosphorylation(GO:0072355)
1.0 7.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.9 16.1 GO:0015809 arginine transport(GO:0015809)
0.9 2.7 GO:0015825 L-serine transport(GO:0015825)
0.8 4.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.7 5.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.7 3.5 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.7 3.3 GO:0060356 leucine import(GO:0060356)
0.6 4.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.5 2.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.4 1.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.4 4.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 1.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3 1.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 1.1 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.2 5.9 GO:0043486 histone exchange(GO:0043486)
0.2 5.7 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.2 2.2 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 3.6 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.2 1.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 5.0 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.2 1.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 10.0 GO:0006826 iron ion transport(GO:0006826)
0.1 22.3 GO:0016579 protein deubiquitination(GO:0016579)
0.1 1.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 9.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 1.9 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 2.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.8 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 2.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.7 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 2.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 1.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 1.4 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 2.2 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 5.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.4 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.6 9.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.5 1.5 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.5 4.9 GO:0042382 paraspeckles(GO:0042382)
0.2 1.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 0.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 9.4 GO:0015030 Cajal body(GO:0015030)
0.2 14.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.3 GO:0070187 telosome(GO:0070187)
0.1 5.6 GO:0002102 podosome(GO:0002102)
0.1 15.6 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 4.1 GO:0005795 Golgi stack(GO:0005795)
0.0 17.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 4.0 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.1 GO:0031430 M band(GO:0031430)
0.0 8.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.6 GO:0001650 fibrillar center(GO:0001650)
0.0 1.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.0 GO:0005840 ribosome(GO:0005840)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.2 GO:0019202 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
3.2 9.6 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
3.1 18.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
2.3 6.9 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.9 9.4 GO:0008859 exoribonuclease II activity(GO:0008859)
1.8 16.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
1.5 7.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.4 4.3 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
1.4 4.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
1.4 4.1 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
1.1 6.4 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.0 4.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.8 2.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.7 4.0 GO:0032357 oxidized purine DNA binding(GO:0032357)
0.7 10.0 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.6 7.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.6 5.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.4 2.7 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.4 2.6 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.3 1.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 1.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 2.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 22.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 3.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 4.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.4 GO:0050815 phosphoserine binding(GO:0050815)
0.1 1.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.8 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 1.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 3.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
0.1 1.8 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 11.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.4 GO:0031005 filamin binding(GO:0031005)
0.0 1.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 4.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 4.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 6.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.4 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.6 GO:0070402 NADPH binding(GO:0070402)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 4.1 GO:0002020 protease binding(GO:0002020)
0.0 4.7 GO:0042393 histone binding(GO:0042393)
0.0 2.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 6.4 PID REELIN PATHWAY Reelin signaling pathway
0.1 7.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 2.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 6.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 3.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 23.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.5 16.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.5 11.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 5.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.5 29.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 9.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 1.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 6.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 9.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 1.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 4.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS