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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Barhl1

Z-value: 0.81

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Transcription factors associated with Barhl1

Gene Symbol Gene ID Gene Info
Barhl1
ENSMUSG00000026805.15 Barhl1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Barhl1mm39_v1_chr2_-_28806639_28806680-0.363.0e-02Click!

Activity profile of Barhl1 motif

Sorted Z-values of Barhl1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Barhl1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_90638580 9.76 ENSMUST00000042755.7
ENSMUST00000200693.2
Afp
alpha fetoprotein
chr16_-_16681839 4.26 ENSMUST00000100136.4
Igll1
immunoglobulin lambda-like polypeptide 1
chr18_-_32692967 2.98 ENSMUST00000174000.2
ENSMUST00000174459.2
Gypc
glycophorin C
chr11_+_61967821 2.63 ENSMUST00000092415.9
ENSMUST00000201015.4
ENSMUST00000202744.4
ENSMUST00000201723.4
ENSMUST00000202179.2
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr15_-_100579450 2.08 ENSMUST00000230740.2
Cela1
chymotrypsin-like elastase family, member 1
chr15_-_100579813 1.85 ENSMUST00000230572.2
Cela1
chymotrypsin-like elastase family, member 1
chr11_+_116089678 1.63 ENSMUST00000021130.7
Ten1
TEN1 telomerase capping complex subunit
chr4_-_117013396 1.49 ENSMUST00000102696.5
Rps8
ribosomal protein S8
chr5_+_149601688 1.38 ENSMUST00000100404.6
B3glct
beta-3-glucosyltransferase
chr8_-_85567256 1.32 ENSMUST00000003911.13
ENSMUST00000109761.9
ENSMUST00000128035.2
Rad23a
RAD23 homolog A, nucleotide excision repair protein
chr6_+_123100382 1.30 ENSMUST00000032248.8
Clec4a2
C-type lectin domain family 4, member a2
chr17_+_7292967 1.22 ENSMUST00000097422.6
Gm1604b
predicted gene 1604b
chr3_-_75177378 1.14 ENSMUST00000039047.5
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chrX_+_162694397 1.03 ENSMUST00000140845.2
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr3_-_88317601 0.84 ENSMUST00000193338.6
ENSMUST00000056370.13
Pmf1
polyamine-modulated factor 1
chr7_+_97492124 0.82 ENSMUST00000033040.12
Pak1
p21 (RAC1) activated kinase 1
chr18_-_42395207 0.74 ENSMUST00000097590.5
Lars
leucyl-tRNA synthetase
chr12_-_54842488 0.68 ENSMUST00000005798.9
Snx6
sorting nexin 6
chr18_-_42395131 0.68 ENSMUST00000236102.2
Lars
leucyl-tRNA synthetase
chr10_+_58207229 0.67 ENSMUST00000238939.2
Lims1
LIM and senescent cell antigen-like domains 1
chr6_-_129853617 0.65 ENSMUST00000014687.11
ENSMUST00000122219.2
Klra17
killer cell lectin-like receptor, subfamily A, member 17
chr19_-_34143437 0.61 ENSMUST00000025686.9
Ankrd22
ankyrin repeat domain 22
chr3_-_130503041 0.58 ENSMUST00000043937.9
Ostc
oligosaccharyltransferase complex subunit (non-catalytic)
chr15_-_58261093 0.57 ENSMUST00000227274.3
Anxa13
annexin A13
chr5_-_23988696 0.52 ENSMUST00000119946.8
Pus7
pseudouridylate synthase 7
chr11_+_78717398 0.52 ENSMUST00000147875.9
ENSMUST00000141321.2
Lyrm9
LYR motif containing 9
chr2_-_104680104 0.51 ENSMUST00000028593.11
Prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr11_+_96209093 0.50 ENSMUST00000049241.9
Hoxb4
homeobox B4
chr3_-_19319155 0.48 ENSMUST00000091314.11
Pde7a
phosphodiesterase 7A
chr10_+_128583734 0.48 ENSMUST00000163377.10
Pym1
PYM homolog 1, exon junction complex associated factor
chr11_+_101473062 0.45 ENSMUST00000039581.14
ENSMUST00000100403.9
ENSMUST00000107194.8
ENSMUST00000128614.2
Tmem106a
transmembrane protein 106A
chr5_-_23988551 0.44 ENSMUST00000148618.8
Pus7
pseudouridylate synthase 7
chr17_-_25334879 0.44 ENSMUST00000024987.6
ENSMUST00000115181.9
Telo2
telomere maintenance 2
chr6_+_113023419 0.44 ENSMUST00000138278.2
Thumpd3
THUMP domain containing 3
chr10_-_126866682 0.43 ENSMUST00000040560.11
Tsfm
Ts translation elongation factor, mitochondrial
chr14_+_64097739 0.43 ENSMUST00000022528.6
Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr2_+_122256913 0.43 ENSMUST00000110525.8
Slc28a2
solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chr2_-_73284262 0.42 ENSMUST00000102679.8
Wipf1
WAS/WASL interacting protein family, member 1
chrX_+_41241049 0.42 ENSMUST00000128799.3
Stag2
stromal antigen 2
chr6_+_88879233 0.41 ENSMUST00000055022.15
ENSMUST00000204765.3
ENSMUST00000153874.8
Tpra1
transmembrane protein, adipocyte asscociated 1
chr3_-_146476331 0.37 ENSMUST00000106138.8
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr10_+_101994841 0.36 ENSMUST00000020039.13
Mgat4c
MGAT4 family, member C
chr6_-_41613322 0.33 ENSMUST00000031902.7
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chrX_+_108240356 0.33 ENSMUST00000139259.2
ENSMUST00000060013.4
Gm6377
predicted gene 6377
chr2_-_86944911 0.28 ENSMUST00000216088.3
Olfr259
olfactory receptor 259
chr14_-_26256025 0.28 ENSMUST00000139075.8
ENSMUST00000102956.8
Slmap
sarcolemma associated protein
chr15_+_25752963 0.28 ENSMUST00000022882.12
ENSMUST00000135173.8
Myo10
myosin X
chr6_+_42885812 0.28 ENSMUST00000216408.2
Olfr447
olfactory receptor 447
chr11_+_54486925 0.27 ENSMUST00000218995.2
Rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr6_+_129568745 0.27 ENSMUST00000032268.14
ENSMUST00000112063.9
ENSMUST00000119520.8
Klrd1
killer cell lectin-like receptor, subfamily D, member 1
chr3_-_146475974 0.26 ENSMUST00000106137.8
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr16_+_92089268 0.24 ENSMUST00000047383.10
Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr1_-_75254989 0.23 ENSMUST00000039534.11
Resp18
regulated endocrine-specific protein 18
chr11_-_79418500 0.22 ENSMUST00000154415.2
Evi2a
ecotropic viral integration site 2a
chr15_+_102240134 0.19 ENSMUST00000113682.9
ENSMUST00000001331.13
ENSMUST00000171244.2
Myg1
melanocyte proliferating gene 1
chr2_-_111965322 0.19 ENSMUST00000213696.2
Olfr1316
olfactory receptor 1316
chr2_-_85632888 0.18 ENSMUST00000217410.3
ENSMUST00000216425.3
Olfr1016
olfactory receptor 1016
chr8_+_31579499 0.18 ENSMUST00000036631.14
Dusp26
dual specificity phosphatase 26 (putative)
chr2_-_45000389 0.18 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
Zeb2
zinc finger E-box binding homeobox 2
chr5_-_87630117 0.17 ENSMUST00000079811.13
ENSMUST00000144144.3
Ugt2a2
UDP glucuronosyltransferase 2 family, polypeptide A2
chr9_+_19533374 0.17 ENSMUST00000213725.2
ENSMUST00000208694.2
Zfp317
zinc finger protein 317
chr14_+_25980463 0.16 ENSMUST00000173155.8
Duxbl1
double homeobox B-like 1
chr8_+_72635863 0.15 ENSMUST00000188685.7
Zfp709
zinc finger protein 709
chr14_+_53599724 0.13 ENSMUST00000196105.2
Trav13n-4
T cell receptor alpha variable 13N-4
chr17_+_37710293 0.12 ENSMUST00000216844.2
ENSMUST00000215974.2
ENSMUST00000215894.2
Olfr107
olfactory receptor 107
chrX_-_74621828 0.11 ENSMUST00000033545.6
Rab39b
RAB39B, member RAS oncogene family
chr3_+_32490300 0.11 ENSMUST00000029201.14
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr17_-_32491339 0.10 ENSMUST00000237008.2
Brd4
bromodomain containing 4
chr8_+_31579633 0.10 ENSMUST00000170204.8
Dusp26
dual specificity phosphatase 26 (putative)
chr18_+_46730765 0.09 ENSMUST00000238168.2
ENSMUST00000078079.11
ENSMUST00000168382.2
ENSMUST00000235849.2
ENSMUST00000235973.2
ENSMUST00000235455.2
ENSMUST00000237478.2
Eif1a
eukaryotic translation initiation factor 1A
chr16_+_32002750 0.09 ENSMUST00000231512.2
Bex6
brain expressed family member 6
chr10_+_69623262 0.09 ENSMUST00000183240.2
Ank3
ankyrin 3, epithelial
chr10_+_33913593 0.08 ENSMUST00000095758.3
Trappc3l
trafficking protein particle complex 3 like
chr4_+_112089442 0.07 ENSMUST00000038455.12
ENSMUST00000170945.2
Skint3
selection and upkeep of intraepithelial T cells 3
chr14_-_9015639 0.06 ENSMUST00000112656.4
Synpr
synaptoporin
chr10_+_101994719 0.06 ENSMUST00000138522.8
ENSMUST00000163753.8
ENSMUST00000138016.8
Mgat4c
MGAT4 family, member C
chr15_+_28203872 0.05 ENSMUST00000067048.8
Dnah5
dynein, axonemal, heavy chain 5
chr3_+_37402495 0.05 ENSMUST00000138563.9
Fgf2
fibroblast growth factor 2
chr6_-_130044234 0.04 ENSMUST00000119096.2
Klra4
killer cell lectin-like receptor, subfamily A, member 4
chr10_-_5019044 0.04 ENSMUST00000095899.5
Syne1
spectrin repeat containing, nuclear envelope 1
chr6_+_90078412 0.03 ENSMUST00000089417.8
ENSMUST00000226577.2
Vmn1r50
vomeronasal 1 receptor 50
chr3_+_37402795 0.03 ENSMUST00000200585.5
ENSMUST00000038885.10
Fgf2
fibroblast growth factor 2
chr11_-_102076028 0.02 ENSMUST00000107156.9
ENSMUST00000021297.6
Lsm12
LSM12 homolog
chr19_-_11816583 0.02 ENSMUST00000214887.2
Olfr1417
olfactory receptor 1417
chr2_-_79959178 0.00 ENSMUST00000102654.11
ENSMUST00000102655.10
Pde1a
phosphodiesterase 1A, calmodulin-dependent

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.6 3.9 GO:0060309 elastin catabolic process(GO:0060309)
0.5 1.4 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.2 0.8 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.2 1.4 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.4 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.4 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.1 1.6 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 1.0 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.0 1.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 3.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 4.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 1.3 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.3 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 1.0 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1990879 CST complex(GO:1990879)
0.2 0.8 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 1.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.7 GO:0097422 tubular endosome(GO:0097422)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 4.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.8 GO:0071437 invadopodium(GO:0071437)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.3 GO:0000502 proteasome complex(GO:0000502)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.8 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.5 1.4 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.1 0.4 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.1 0.7 GO:0034452 dynactin binding(GO:0034452)
0.1 0.3 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.1 1.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.6 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 4.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 3.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 4.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase