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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Batf3

Z-value: 0.75

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Transcription factors associated with Batf3

Gene Symbol Gene ID Gene Info
Batf3
ENSMUSG00000026630.10 Batf3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Batf3mm39_v1_chr1_+_190830522_1908306330.464.7e-03Click!

Activity profile of Batf3 motif

Sorted Z-values of Batf3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Batf3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_-_67682312 4.20 ENSMUST00000224799.2
Spire1
spire type actin nucleation factor 1
chr6_-_86646118 2.60 ENSMUST00000001184.10
Mxd1
MAX dimerization protein 1
chr3_+_134918298 2.15 ENSMUST00000062893.12
Cenpe
centromere protein E
chr14_-_87378641 1.72 ENSMUST00000168889.3
ENSMUST00000022599.14
Diaph3
diaphanous related formin 3
chr12_+_73333641 1.72 ENSMUST00000153941.8
ENSMUST00000122920.8
ENSMUST00000101313.4
Slc38a6
solute carrier family 38, member 6
chr4_+_130253925 1.70 ENSMUST00000105994.4
Snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr15_+_79231720 1.65 ENSMUST00000096350.11
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr15_+_79232137 1.61 ENSMUST00000163691.3
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr7_+_3706992 1.59 ENSMUST00000006496.15
ENSMUST00000108623.8
ENSMUST00000139818.2
ENSMUST00000108625.8
Rps9
ribosomal protein S9
chr6_-_83030759 1.49 ENSMUST00000134606.8
Htra2
HtrA serine peptidase 2
chr14_+_51045298 1.47 ENSMUST00000036126.7
Parp2
poly (ADP-ribose) polymerase family, member 2
chr12_-_69205882 1.43 ENSMUST00000037023.9
Rps29
ribosomal protein S29
chr13_-_22227114 1.37 ENSMUST00000091741.6
H2ac11
H2A clustered histone 11
chr17_-_71833752 1.33 ENSMUST00000232863.2
ENSMUST00000024851.10
Ndc80
NDC80 kinetochore complex component
chr14_-_51045182 1.24 ENSMUST00000227614.2
Ccnb1ip1
cyclin B1 interacting protein 1
chr2_-_124965537 1.16 ENSMUST00000142718.8
ENSMUST00000152367.8
ENSMUST00000067780.10
ENSMUST00000147105.8
Myef2
myelin basic protein expression factor 2, repressor
chr6_-_83031358 1.12 ENSMUST00000113962.8
ENSMUST00000089645.13
ENSMUST00000113963.8
Htra2
HtrA serine peptidase 2
chr7_+_97437709 1.12 ENSMUST00000206984.2
Pak1
p21 (RAC1) activated kinase 1
chr13_+_22227359 1.08 ENSMUST00000110452.2
H2bc11
H2B clustered histone 11
chr4_-_41275091 0.93 ENSMUST00000030143.13
ENSMUST00000108068.8
Ubap2
ubiquitin-associated protein 2
chr3_+_40754489 0.91 ENSMUST00000203295.3
Plk4
polo like kinase 4
chr2_+_120439858 0.86 ENSMUST00000124187.8
Haus2
HAUS augmin-like complex, subunit 2
chr12_+_4132567 0.85 ENSMUST00000020986.15
ENSMUST00000049584.6
Dnajc27
DnaJ heat shock protein family (Hsp40) member C27
chr5_+_142946098 0.83 ENSMUST00000031565.15
ENSMUST00000198017.5
Fscn1
fascin actin-bundling protein 1
chr19_-_61215743 0.83 ENSMUST00000237386.2
Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr6_-_124441731 0.83 ENSMUST00000008297.5
Clstn3
calsyntenin 3
chr16_+_38383154 0.73 ENSMUST00000171687.8
ENSMUST00000002924.15
Tmem39a
transmembrane protein 39a
chr4_-_130253703 0.58 ENSMUST00000134159.3
Zcchc17
zinc finger, CCHC domain containing 17
chr17_-_26727437 0.54 ENSMUST00000236661.2
ENSMUST00000025025.7
Dusp1
dual specificity phosphatase 1
chr7_-_79974166 0.46 ENSMUST00000047362.11
ENSMUST00000121882.8
Rccd1
RCC1 domain containing 1
chr8_-_61407760 0.39 ENSMUST00000110302.8
Clcn3
chloride channel, voltage-sensitive 3
chr5_+_25427860 0.39 ENSMUST00000045737.14
Galnt11
polypeptide N-acetylgalactosaminyltransferase 11
chr7_-_103778992 0.38 ENSMUST00000053743.6
Ubqln5
ubiquilin 5
chr1_-_126758369 0.38 ENSMUST00000112583.8
ENSMUST00000094609.10
Nckap5
NCK-associated protein 5
chr5_+_107645626 0.36 ENSMUST00000152474.8
ENSMUST00000060553.8
Btbd8
BTB (POZ) domain containing 8
chr11_+_83553400 0.35 ENSMUST00000019074.4
Ccl4
chemokine (C-C motif) ligand 4
chr7_+_90091937 0.34 ENSMUST00000061767.5
Crebzf
CREB/ATF bZIP transcription factor
chr9_+_106048116 0.33 ENSMUST00000020490.13
Wdr82
WD repeat domain containing 82
chr8_+_106738105 0.32 ENSMUST00000034375.11
Dus2
dihydrouridine synthase 2
chr2_-_120439981 0.29 ENSMUST00000133612.2
ENSMUST00000102498.8
ENSMUST00000102499.8
Lrrc57
leucine rich repeat containing 57
chrX_+_73352694 0.27 ENSMUST00000130581.2
Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr2_-_120439826 0.22 ENSMUST00000102497.10
Lrrc57
leucine rich repeat containing 57
chr5_-_130284366 0.18 ENSMUST00000026387.11
Sbds
SBDS ribosome maturation factor
chr17_-_24926589 0.17 ENSMUST00000126319.8
Tbl3
transducin (beta)-like 3
chr2_-_120439764 0.17 ENSMUST00000102496.8
Lrrc57
leucine rich repeat containing 57
chr4_+_32238712 0.16 ENSMUST00000108180.9
Bach2
BTB and CNC homology, basic leucine zipper transcription factor 2
chr16_+_38383182 0.16 ENSMUST00000163948.8
Tmem39a
transmembrane protein 39a
chr11_-_69214593 0.14 ENSMUST00000092973.6
Cntrob
centrobin, centrosomal BRCA2 interacting protein
chr11_+_93935021 0.13 ENSMUST00000075695.13
ENSMUST00000092777.11
Spag9
sperm associated antigen 9
chrX_-_8042129 0.08 ENSMUST00000143984.2
Tbc1d25
TBC1 domain family, member 25
chr1_+_75145275 0.07 ENSMUST00000162768.8
ENSMUST00000160439.8
ENSMUST00000027394.12
Zfand2b
zinc finger, AN1 type domain 2B
chr1_-_126758520 0.07 ENSMUST00000162646.8
Nckap5
NCK-associated protein 5
chr7_+_16716989 0.06 ENSMUST00000206129.3
Gm42372
predicted gene, 42372
chr15_-_76906150 0.06 ENSMUST00000230031.2
Mb
myoglobin
chr11_+_19874354 0.06 ENSMUST00000093299.13
Spred2
sprouty-related EVH1 domain containing 2
chr5_-_124170305 0.05 ENSMUST00000040967.9
Vps37b
vacuolar protein sorting 37B
chr11_+_93934940 0.04 ENSMUST00000132079.8
Spag9
sperm associated antigen 9
chr10_-_17823736 0.04 ENSMUST00000037879.8
Heca
hdc homolog, cell cycle regulator
chr14_-_55950939 0.03 ENSMUST00000168729.8
ENSMUST00000228123.2
ENSMUST00000178034.9
Tgm1
transglutaminase 1, K polypeptide
chr9_-_119151428 0.03 ENSMUST00000040853.11
Oxsr1
oxidative-stress responsive 1
chr11_-_70128462 0.03 ENSMUST00000100950.10
0610010K14Rik
RIKEN cDNA 0610010K14 gene
chr7_+_138448061 0.02 ENSMUST00000041097.13
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta
chr17_-_36291087 0.01 ENSMUST00000055454.14
Prr3
proline-rich polypeptide 3
chr11_+_93935066 0.00 ENSMUST00000103168.10
Spag9
sperm associated antigen 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.2 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.9 2.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.5 1.5 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.3 0.9 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 2.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 1.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 1.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 1.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 0.4 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.9 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.8 GO:0030035 microspike assembly(GO:0030035)
0.1 0.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 1.2 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.8 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.4 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.8 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0 3.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.5 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 2.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.2 0.8 GO:0044393 microspike(GO:0044393)
0.2 2.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.9 GO:0098536 deuterosome(GO:0098536)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 4.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.7 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.1 GO:0071437 invadopodium(GO:0071437)
0.0 3.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0042581 specific granule(GO:0042581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.3 2.1 GO:0043515 kinetochore binding(GO:0043515)
0.3 0.8 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.2 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 3.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 4.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.7 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 3.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase