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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Cebpb

Z-value: 3.45

Motif logo

Transcription factors associated with Cebpb

Gene Symbol Gene ID Gene Info
ENSMUSG00000056501.4 Cebpb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cebpbmm39_v1_chr2_+_167530835_167530894-0.077.0e-01Click!

Activity profile of Cebpb motif

Sorted Z-values of Cebpb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Cebpb

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_109678685 28.41 ENSMUST00000112022.5
cathelicidin antimicrobial peptide
chr7_+_13467422 26.09 ENSMUST00000086148.8
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr9_+_110248815 23.01 ENSMUST00000035061.9
neutrophilic granule protein
chrX_-_161747552 19.67 ENSMUST00000038769.3
S100 calcium binding protein G
chr10_+_23727325 18.30 ENSMUST00000020190.8
vanin 3
chr2_-_32277773 15.94 ENSMUST00000050785.14
lipocalin 2
chr2_-_32278245 15.71 ENSMUST00000192241.2
lipocalin 2
chr11_-_99383938 14.85 ENSMUST00000006969.8
keratin 23
chr8_-_46664321 14.55 ENSMUST00000034049.5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr10_+_79722081 13.96 ENSMUST00000046091.7
elastase, neutrophil expressed
chr9_+_110867807 11.93 ENSMUST00000197575.2
lactotransferrin
chr7_-_44181477 10.69 ENSMUST00000098483.9
ENSMUST00000035323.6
Spi-B transcription factor (Spi-1/PU.1 related)
chr7_+_13357892 10.33 ENSMUST00000108525.4
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
chr19_-_11618165 10.20 ENSMUST00000186023.7
membrane-spanning 4-domains, subfamily A, member 3
chr16_+_22710785 10.12 ENSMUST00000023583.7
ENSMUST00000232098.2
alpha-2-HS-glycoprotein
chrX_-_137985960 10.01 ENSMUST00000033626.15
ENSMUST00000060824.4
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr16_+_22877000 9.77 ENSMUST00000039492.14
ENSMUST00000023589.15
ENSMUST00000089902.8
kininogen 1
chr19_-_11618192 9.19 ENSMUST00000112984.4
membrane-spanning 4-domains, subfamily A, member 3
chrX_-_137985979 8.89 ENSMUST00000152457.2
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr7_-_13988795 8.53 ENSMUST00000184731.8
ENSMUST00000076576.7
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
chr2_+_24235300 8.48 ENSMUST00000114485.9
ENSMUST00000114482.3
interleukin 1 receptor antagonist
chr19_-_15902292 7.55 ENSMUST00000025542.10
phosphoserine aminotransferase 1
chr9_-_71070506 7.47 ENSMUST00000074465.9
aquaporin 9
chr14_+_40827108 7.09 ENSMUST00000224514.2
methionine adenosyltransferase I, alpha
chr9_+_7558449 6.59 ENSMUST00000018765.4
matrix metallopeptidase 8
chr1_+_134110142 6.45 ENSMUST00000082060.10
ENSMUST00000153856.8
ENSMUST00000133701.8
ENSMUST00000132873.8
chitinase-like 1
chr7_+_78563150 6.31 ENSMUST00000118867.8
interferon-stimulated protein
chr7_+_78563964 6.22 ENSMUST00000120331.4
interferon-stimulated protein
chr2_+_117942357 6.11 ENSMUST00000039559.9
thrombospondin 1
chr4_-_133694543 6.00 ENSMUST00000123234.8
high mobility group nucleosomal binding domain 2
chr11_+_115353290 5.82 ENSMUST00000106532.4
ENSMUST00000092445.12
ENSMUST00000153466.2
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr2_+_158148413 5.78 ENSMUST00000109491.8
ENSMUST00000016168.9
lipopolysaccharide binding protein
chr8_-_120567236 5.51 ENSMUST00000211873.2
ENSMUST00000168698.2
ENSMUST00000034285.14
coactosin-like 1 (Dictyostelium)
chr12_-_81014755 5.37 ENSMUST00000218342.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr7_+_78563184 5.34 ENSMUST00000121645.8
interferon-stimulated protein
chr15_-_103161237 5.30 ENSMUST00000154510.8
nuclear factor, erythroid derived 2
chr7_+_78563513 5.29 ENSMUST00000038142.15
interferon-stimulated protein
chr8_+_75820240 5.22 ENSMUST00000005548.8
heme oxygenase 1
chr7_-_13856967 5.04 ENSMUST00000098809.4
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3
chr7_-_45264908 4.99 ENSMUST00000033099.6
fibroblast growth factor 21
chr14_+_40826970 4.86 ENSMUST00000225720.2
methionine adenosyltransferase I, alpha
chr3_+_20011405 4.82 ENSMUST00000108325.9
ceruloplasmin
chr12_-_81014849 4.81 ENSMUST00000095572.5
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr10_+_97318223 4.72 ENSMUST00000163448.4
decorin
chr12_-_101784727 4.71 ENSMUST00000222587.2
fibulin 5
chr11_+_53410552 4.58 ENSMUST00000108987.8
ENSMUST00000121334.8
ENSMUST00000117061.8
septin 8
chr3_+_20011251 4.54 ENSMUST00000108328.8
ceruloplasmin
chr14_+_40827317 4.50 ENSMUST00000047286.7
methionine adenosyltransferase I, alpha
chr17_+_57665691 4.45 ENSMUST00000086763.13
ENSMUST00000233376.2
ENSMUST00000233840.2
ENSMUST00000232808.2
ENSMUST00000004850.8
adhesion G protein-coupled receptor E1
chr3_+_82933383 4.41 ENSMUST00000029630.15
ENSMUST00000166581.4
fibrinogen alpha chain
chr2_+_22664094 4.24 ENSMUST00000014290.15
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr3_+_20011201 4.15 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr4_-_43558386 4.11 ENSMUST00000130353.2
talin 1
chr15_+_57849269 4.01 ENSMUST00000050374.3
family with sequence similarity 83, member A
chr10_+_80765900 4.00 ENSMUST00000015456.10
ENSMUST00000220246.2
growth arrest and DNA-damage-inducible 45 beta
chr2_-_164198427 3.92 ENSMUST00000109367.10
secretory leukocyte peptidase inhibitor
chr1_+_164624200 3.80 ENSMUST00000027861.6
dermatopontin
chr3_+_82915031 3.75 ENSMUST00000048486.13
ENSMUST00000194175.2
fibrinogen gamma chain
chr14_+_22069877 3.54 ENSMUST00000161249.8
ENSMUST00000159777.8
ENSMUST00000162540.2
leucine rich melanocyte differentiation associated
chr3_-_89820451 3.54 ENSMUST00000029559.7
ENSMUST00000197679.5
interleukin 6 receptor, alpha
chr17_+_48653429 3.52 ENSMUST00000024791.15
triggering receptor expressed on myeloid cells 2
chr1_+_74414354 3.46 ENSMUST00000187516.7
ENSMUST00000027368.6
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr12_-_101785307 3.34 ENSMUST00000021603.9
fibulin 5
chr4_+_126915104 3.27 ENSMUST00000030623.8
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr15_-_37459570 3.27 ENSMUST00000119730.8
ENSMUST00000120746.8
neurocalcin delta
chr10_-_88192852 3.15 ENSMUST00000020249.2
DNA-damage regulated autophagy modulator 1
chr17_+_47908025 3.15 ENSMUST00000183206.2
cyclin D3
chr18_-_36859732 3.12 ENSMUST00000061829.8
CD14 antigen
chr13_+_25127127 3.09 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr13_-_61084358 3.01 ENSMUST00000225859.2
ENSMUST00000225167.2
ENSMUST00000021880.10
predicted gene, 49391
cytotoxic T lymphocyte-associated protein 2 alpha
chrX_-_56384089 2.95 ENSMUST00000033468.11
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr14_+_51328534 2.89 ENSMUST00000022428.13
ENSMUST00000171688.9
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr19_-_3979723 2.82 ENSMUST00000051803.8
aldehyde dehydrogenase 3 family, member B1
chr9_-_103107460 2.79 ENSMUST00000165296.8
ENSMUST00000112645.8
transferrin
chr4_-_148172423 2.74 ENSMUST00000030865.9
angiotensin II, type I receptor-associated protein
chr7_-_45480200 2.70 ENSMUST00000107723.9
ENSMUST00000131384.3
glutamate-rich WD repeat containing 1
chr1_-_164281344 2.67 ENSMUST00000193367.2
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr8_-_123202774 2.60 ENSMUST00000014614.4
ring finger protein 166
chr14_+_22069709 2.60 ENSMUST00000075639.11
leucine rich melanocyte differentiation associated
chr12_+_37291728 2.59 ENSMUST00000160768.8
alkylglycerol monooxygenase
chr16_-_22848153 2.59 ENSMUST00000232459.2
kininogen 2
chr11_-_72441054 2.58 ENSMUST00000021154.7
spinster homolog 3
chr5_-_104125226 2.53 ENSMUST00000048118.15
hydroxysteroid (17-beta) dehydrogenase 13
chr9_+_5298669 2.52 ENSMUST00000238505.2
caspase 1
chr19_+_34268053 2.51 ENSMUST00000025691.13
Fas (TNF receptor superfamily member 6)
chr7_+_30450896 2.49 ENSMUST00000182229.8
ENSMUST00000080518.14
ENSMUST00000182227.8
ENSMUST00000182721.8
suprabasin
chr6_-_56878854 2.48 ENSMUST00000101367.9
5'-nucleotidase, cytosolic III
chr14_+_3576275 2.44 ENSMUST00000151926.8
ubiquitin-conjugating enzyme E2E 2
chr19_+_34268071 2.41 ENSMUST00000112472.4
ENSMUST00000235232.2
Fas (TNF receptor superfamily member 6)
chr4_-_136626073 2.40 ENSMUST00000046285.6
complement component 1, q subcomponent, alpha polypeptide
chr9_-_123768720 2.38 ENSMUST00000026911.6
chemokine (C-C motif) receptor 1
chr3_+_109030419 2.35 ENSMUST00000029477.11
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24
chr11_+_49141410 2.34 ENSMUST00000129588.2
mannoside acetylglucosaminyltransferase 1
chr4_-_151129020 2.34 ENSMUST00000103204.11
period circadian clock 3
chr2_+_32766126 2.32 ENSMUST00000028135.15
niban apoptosis regulator 2
chr5_-_104125270 2.30 ENSMUST00000112803.3
hydroxysteroid (17-beta) dehydrogenase 13
chr16_-_22847760 2.30 ENSMUST00000039338.13
kininogen 2
chr2_-_118378020 2.29 ENSMUST00000110859.3
BCL2 modifying factor
chr11_-_115968745 2.24 ENSMUST00000156545.2
ENSMUST00000075036.9
ENSMUST00000106451.8
unc-13 homolog D
chr16_-_22847829 2.22 ENSMUST00000100046.9
kininogen 2
chr4_+_125918333 2.22 ENSMUST00000106162.8
colony stimulating factor 3 receptor (granulocyte)
chr7_+_45084257 2.22 ENSMUST00000003964.17
glycogen synthase 1, muscle
chr17_+_48653493 2.19 ENSMUST00000113237.4
triggering receptor expressed on myeloid cells 2
chr17_+_29333116 2.17 ENSMUST00000233717.2
ENSMUST00000141239.2
RAB44, member RAS oncogene family
chr2_+_155593030 2.16 ENSMUST00000029140.12
ENSMUST00000132608.2
protein C receptor, endothelial
chr9_-_103107495 2.13 ENSMUST00000035158.16
transferrin
chr5_-_104125192 2.12 ENSMUST00000120320.8
hydroxysteroid (17-beta) dehydrogenase 13
chr12_+_76884182 2.12 ENSMUST00000041008.10
farnesyltransferase, CAAX box, beta
chr19_+_55240357 2.10 ENSMUST00000225551.2
acyl-CoA synthetase long-chain family member 5
chr7_+_126461117 2.08 ENSMUST00000037248.10
HIRA interacting protein 3
chr18_-_38734389 2.06 ENSMUST00000025295.8
sprouty RTK signaling antagonist 4
chr16_-_22847808 2.03 ENSMUST00000115349.9
kininogen 2
chr3_+_84573499 2.00 ENSMUST00000107682.2
transmembrane protein 154
chr8_-_34419826 1.98 ENSMUST00000033995.14
ENSMUST00000033994.15
ENSMUST00000191473.7
ENSMUST00000053251.12
RNA binding protein gene with multiple splicing
chr1_+_40123858 1.97 ENSMUST00000027243.13
interleukin 1 receptor, type II
chr3_+_123240562 1.95 ENSMUST00000029603.10
protease, serine 12 neurotrypsin (motopsin)
chr11_+_49141339 1.90 ENSMUST00000101293.11
mannoside acetylglucosaminyltransferase 1
chr5_+_8010445 1.87 ENSMUST00000115421.3
STEAP family member 4
chr16_-_93726399 1.84 ENSMUST00000177648.8
ENSMUST00000142083.2
claudin 14
chr6_+_136509922 1.78 ENSMUST00000187429.4
activating transcription factor 7 interacting protein
chr7_+_126461601 1.77 ENSMUST00000132808.2
HIRA interacting protein 3
chr1_-_79838897 1.76 ENSMUST00000190724.2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr14_-_55950545 1.74 ENSMUST00000002389.9
ENSMUST00000226907.2
transglutaminase 1, K polypeptide
chr15_-_103218876 1.72 ENSMUST00000079824.6
G protein-coupled receptor 84
chr16_+_57173456 1.70 ENSMUST00000159816.8
filamin A interacting protein 1-like
chr6_+_115398996 1.70 ENSMUST00000000450.5
peroxisome proliferator activated receptor gamma
chr10_-_111829393 1.69 ENSMUST00000161870.3
GLI pathogenesis-related 1 (glioma)
chr11_-_120534469 1.68 ENSMUST00000141254.8
ENSMUST00000170556.8
ENSMUST00000151876.8
ENSMUST00000026133.15
ENSMUST00000139706.2
pyrroline-5-carboxylate reductase 1
chr12_-_113843161 1.62 ENSMUST00000103451.5
immunoglobulin heavy variable 2-9
chr6_-_87786736 1.60 ENSMUST00000032134.9
RAB43, member RAS oncogene family
chr9_-_42035560 1.59 ENSMUST00000060989.9
sortilin-related receptor, LDLR class A repeats-containing
chr5_-_123126550 1.56 ENSMUST00000086200.11
ENSMUST00000156474.8
lysine (K)-specific demethylase 2B
chr13_+_95460110 1.54 ENSMUST00000221807.2
zinc finger, BED type containing 3
chr14_-_55950939 1.54 ENSMUST00000168729.8
ENSMUST00000228123.2
ENSMUST00000178034.9
transglutaminase 1, K polypeptide
chr7_+_45084300 1.53 ENSMUST00000211150.2
glycogen synthase 1, muscle
chr1_-_162726234 1.51 ENSMUST00000111510.8
ENSMUST00000045902.13
flavin containing monooxygenase 2
chr17_-_57501170 1.50 ENSMUST00000005976.8
tumor necrosis factor (ligand) superfamily, member 14
chr7_-_109201859 1.50 ENSMUST00000208583.2
DENN domain containing 2B
chr4_+_150572847 1.50 ENSMUST00000105680.9
arginine glutamic acid dipeptide (RE) repeats
chr10_-_80269436 1.44 ENSMUST00000105346.10
ENSMUST00000020377.13
ENSMUST00000105340.8
ENSMUST00000020379.13
ENSMUST00000105344.8
ENSMUST00000105342.8
ENSMUST00000105345.10
ENSMUST00000105343.8
transcription factor 3
chr13_+_49835667 1.42 ENSMUST00000172254.3
isoleucine-tRNA synthetase
chr17_+_27276262 1.33 ENSMUST00000049308.9
inositol 1,4,5-triphosphate receptor 3
chr2_-_129213050 1.33 ENSMUST00000028881.14
interleukin 1 beta
chr12_+_37291632 1.32 ENSMUST00000049874.14
alkylglycerol monooxygenase
chr16_+_57369595 1.32 ENSMUST00000159414.2
filamin A interacting protein 1-like
chr4_+_152123772 1.30 ENSMUST00000084116.13
ENSMUST00000103197.5
nucleolar protein 9
chr17_+_87270504 1.28 ENSMUST00000024956.15
ras homolog family member Q
chr5_+_75312939 1.25 ENSMUST00000202681.4
ENSMUST00000000476.15
platelet derived growth factor receptor, alpha polypeptide
chr7_-_13723513 1.25 ENSMUST00000165167.8
ENSMUST00000108520.4
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4
chr8_-_37419567 1.21 ENSMUST00000163663.3
deleted in liver cancer 1
chr11_-_101442663 1.19 ENSMUST00000017290.11
breast cancer 1, early onset
chr9_+_107957621 1.19 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr5_-_137531413 1.19 ENSMUST00000168746.8
guanine nucleotide binding protein (G protein), beta 2
chr18_-_52662917 1.16 ENSMUST00000171470.8
lysyl oxidase
chr5_-_124003553 1.16 ENSMUST00000057145.7
hydroxycarboxylic acid receptor 2
chr16_+_45044678 1.13 ENSMUST00000102802.10
ENSMUST00000063654.6
B and T lymphocyte associated
chr9_+_107957640 1.11 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr15_+_59520199 1.11 ENSMUST00000067543.8
tribbles pseudokinase 1
chr2_-_152185901 1.10 ENSMUST00000040312.7
tribbles pseudokinase 3
chr8_+_95055829 1.07 ENSMUST00000034218.5
ENSMUST00000212134.2
solute carrier family 12, member 3
chr7_-_45084012 0.94 ENSMUST00000107771.12
ENSMUST00000211666.2
RuvB-like protein 2
chr12_+_37292029 0.91 ENSMUST00000160390.2
alkylglycerol monooxygenase
chr6_+_34686543 0.91 ENSMUST00000031775.13
caldesmon 1
chr4_+_124635635 0.90 ENSMUST00000094782.10
ENSMUST00000153837.8
ENSMUST00000154229.2
inositol polyphosphate-5-phosphatase B
chr17_-_32503689 0.89 ENSMUST00000127893.8
bromodomain containing 4
chr10_-_6930376 0.86 ENSMUST00000105617.8
interaction protein for cytohesin exchange factors 1
chr19_+_12438125 0.85 ENSMUST00000081035.9
macrophage expressed gene 1
chr13_-_117161921 0.85 ENSMUST00000223949.2
poly (ADP-ribose) polymerase family, member 8
chrX_-_166047275 0.85 ENSMUST00000112170.2
toll-like receptor 8
chr3_+_31150982 0.82 ENSMUST00000118204.2
SKI-like
chr18_-_52662728 0.81 ENSMUST00000025409.9
lysyl oxidase
chr15_-_37458768 0.79 ENSMUST00000116445.9
neurocalcin delta
chr13_+_91071077 0.79 ENSMUST00000051955.9
ribosomal protein S23
chr7_-_126461522 0.79 ENSMUST00000206968.2
INO80 complex subunit E
chr12_+_8027767 0.78 ENSMUST00000037520.14
apolipoprotein B
chr14_-_54647647 0.74 ENSMUST00000228488.2
ENSMUST00000195970.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr15_+_25940859 0.74 ENSMUST00000226750.2
reticulophagy regulator 1
chr13_+_49835576 0.73 ENSMUST00000165316.8
ENSMUST00000047363.14
isoleucine-tRNA synthetase
chr11_+_69983531 0.72 ENSMUST00000124721.2
asialoglycoprotein receptor 2
chr17_-_29226700 0.71 ENSMUST00000233441.2
serine/threonine kinase 38
chr7_-_45083688 0.70 ENSMUST00000210439.2
RuvB-like protein 2
chr8_+_95113066 0.69 ENSMUST00000161576.8
ENSMUST00000034220.8
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr19_-_34724689 0.68 ENSMUST00000009522.4
solute carrier family 16 (monocarboxylic acid transporters), member 12
chr11_-_3321307 0.68 ENSMUST00000101640.10
ENSMUST00000101642.10
LIM motif-containing protein kinase 2
chr7_-_3551003 0.66 ENSMUST00000065703.9
ENSMUST00000203020.3
ENSMUST00000203821.3
T cell-interacting, activating receptor on myeloid cells 1
chrX_+_7630182 0.62 ENSMUST00000144900.2
ENSMUST00000115677.8
ENSMUST00000101695.9
ENSMUST00000115678.3
transcription factor E3
chr10_+_127126643 0.62 ENSMUST00000026475.15
ENSMUST00000139091.2
ENSMUST00000230446.2
DNA-damage inducible transcript 3
DNA-damage inducible transcript 3
chr13_-_117162041 0.62 ENSMUST00000022239.8
poly (ADP-ribose) polymerase family, member 8
chr15_+_59520493 0.60 ENSMUST00000118228.2
tribbles pseudokinase 1
chr9_-_55190902 0.60 ENSMUST00000164721.8
neuregulin 4
chr6_+_141194886 0.58 ENSMUST00000043259.10
phosphodiesterase 3A, cGMP inhibited
chr1_-_52839530 0.57 ENSMUST00000159725.2
inositol polyphosphate-1-phosphatase
chr4_+_124880223 0.55 ENSMUST00000030687.8
R-spondin 1
chr1_-_87501548 0.54 ENSMUST00000068681.12
neuronal guanine nucleotide exchange factor
chr1_-_171173168 0.54 ENSMUST00000156856.8
ENSMUST00000111296.8
nitrilase 1
chr11_+_69983479 0.52 ENSMUST00000143772.8
asialoglycoprotein receptor 2
chr11_-_115968576 0.52 ENSMUST00000106450.8
unc-13 homolog D
chr18_+_4994600 0.51 ENSMUST00000140448.8
supervillin
chr11_+_106107752 0.50 ENSMUST00000021046.6
DEAD box helicase 42
chr8_+_46924074 0.50 ENSMUST00000034046.13
ENSMUST00000211644.2
acyl-CoA synthetase long-chain family member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.5 31.6 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
6.3 18.9 GO:0033189 response to vitamin A(GO:0033189)
5.8 23.0 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
5.5 16.4 GO:0009087 methionine catabolic process(GO:0009087)
4.7 14.0 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780) neutrophil mediated killing of fungus(GO:0070947)
3.9 23.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.6 14.5 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
3.0 11.9 GO:1900190 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
2.9 5.7 GO:0032499 detection of peptidoglycan(GO:0032499)
2.6 28.4 GO:0002227 innate immune response in mucosa(GO:0002227)
2.1 10.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
2.0 6.1 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
1.9 5.8 GO:0015920 lipopolysaccharide transport(GO:0015920)
1.9 7.5 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
1.7 5.2 GO:0006788 heme oxidation(GO:0006788)
1.6 4.9 GO:0031104 dendrite regeneration(GO:0031104)
1.2 3.5 GO:0070839 divalent metal ion export(GO:0070839)
1.1 4.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.1 4.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.9 2.7 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.9 3.5 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.8 10.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.8 3.1 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.8 3.1 GO:0006507 GPI anchor release(GO:0006507) regulation of high-density lipoprotein particle clearance(GO:0010982)
0.8 2.3 GO:1904092 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.7 2.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.6 2.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.6 5.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.6 4.9 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.6 17.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.6 1.8 GO:0044704 mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297) seminal vesicle development(GO:0061107)
0.6 1.7 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.5 1.6 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.5 1.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.5 2.9 GO:0006651 diacylglycerol biosynthetic process(GO:0006651) positive regulation of phospholipase A2 activity(GO:0032430)
0.5 4.2 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.4 18.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.4 1.3 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.4 1.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.4 15.1 GO:0006825 copper ion transport(GO:0006825)
0.4 1.7 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.4 2.1 GO:0018343 protein farnesylation(GO:0018343)
0.4 2.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.4 1.6 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.4 1.6 GO:2001137 protein retention in Golgi apparatus(GO:0045053) positive regulation of endocytic recycling(GO:2001137)
0.4 1.2 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.4 4.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 25.8 GO:0050819 negative regulation of coagulation(GO:0050819)
0.4 1.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.4 2.3 GO:0015867 ATP transport(GO:0015867)
0.4 1.5 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.4 4.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.4 2.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.3 10.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 6.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.3 4.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 2.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 2.4 GO:0002432 granuloma formation(GO:0002432)
0.3 1.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.3 6.6 GO:0030574 collagen catabolic process(GO:0030574)
0.3 3.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.3 3.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 1.3 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.3 1.6 GO:0072592 oxygen metabolic process(GO:0072592)
0.3 2.3 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.2 0.7 GO:0015881 creatine transport(GO:0015881)
0.2 10.7 GO:0030225 macrophage differentiation(GO:0030225)
0.2 3.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.2 1.7 GO:0006561 proline biosynthetic process(GO:0006561)
0.2 6.0 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.2 5.5 GO:0050832 defense response to fungus(GO:0050832)
0.2 1.4 GO:0002326 B cell lineage commitment(GO:0002326)
0.2 2.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 0.6 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 1.0 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 2.7 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 3.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 2.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 2.8 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 2.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.3 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 1.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.7 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.7 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.1 5.9 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 0.6 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 2.0 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 3.8 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.3 GO:1903936 response to diamide(GO:0072737) cellular response to diamide(GO:0072738) cellular response to sodium arsenite(GO:1903936)
0.1 0.3 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.1 1.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 2.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.8 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.5 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 2.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 1.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.5 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 1.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 3.0 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 3.8 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 4.3 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.5 GO:0002934 desmosome organization(GO:0002934)
0.0 0.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 2.4 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 3.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 2.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 6.8 GO:0008202 steroid metabolic process(GO:0008202)
0.0 0.3 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 2.8 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 1.7 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 3.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0045066 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) regulatory T cell differentiation(GO:0045066)
0.0 0.7 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 10.9 GO:0051726 regulation of cell cycle(GO:0051726)
0.0 2.1 GO:0000209 protein polyubiquitination(GO:0000209)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 11.9 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.8 14.3 GO:0005577 fibrinogen complex(GO:0005577)
1.7 3.5 GO:0070820 tertiary granule(GO:0070820)
1.6 8.1 GO:0071953 elastic fiber(GO:0071953)
1.3 28.4 GO:0042581 specific granule(GO:0042581)
1.0 2.9 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.9 3.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.7 2.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.6 2.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.5 4.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.5 6.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.4 1.3 GO:0034359 mature chylomicron(GO:0034359)
0.4 23.2 GO:0015030 Cajal body(GO:0015030)
0.4 3.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 3.3 GO:0042382 paraspeckles(GO:0042382)
0.3 2.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 2.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 4.7 GO:0098644 complex of collagen trimers(GO:0098644)
0.2 0.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 1.6 GO:0097255 R2TP complex(GO:0097255)
0.2 0.7 GO:1990037 Lewy body core(GO:1990037)
0.1 10.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 4.2 GO:0042101 T cell receptor complex(GO:0042101)
0.1 2.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0033193 Lsd1/2 complex(GO:0033193)
0.1 15.8 GO:0016363 nuclear matrix(GO:0016363)
0.1 17.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 1.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 10.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 29.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 9.0 GO:0005882 intermediate filament(GO:0005882)
0.1 2.0 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 14.4 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.1 6.4 GO:0005901 caveola(GO:0005901)
0.1 13.3 GO:0072562 blood microparticle(GO:0072562)
0.1 4.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0031011 Ino80 complex(GO:0031011)
0.0 3.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 3.3 GO:0016234 inclusion body(GO:0016234)
0.0 2.9 GO:0005811 lipid particle(GO:0005811)
0.0 4.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 6.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 11.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.1 GO:0030027 lamellipodium(GO:0030027)
0.0 2.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 5.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 4.1 GO:0001726 ruffle(GO:0001726)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.0 1.8 GO:0005884 actin filament(GO:0005884)
0.0 4.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 17.6 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 4.7 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 23.2 GO:0008859 exoribonuclease II activity(GO:0008859)
4.1 16.4 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
3.6 25.1 GO:0050656 alcohol sulfotransferase activity(GO:0004027) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
2.8 8.5 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
2.5 19.7 GO:0005499 vitamin D binding(GO:0005499)
1.7 5.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.7 10.1 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
1.6 14.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.6 4.8 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
1.5 16.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
1.5 6.1 GO:0070052 collagen V binding(GO:0070052)
1.5 7.5 GO:0015254 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
1.3 10.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.2 3.7 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.2 4.9 GO:0043120 tumor necrosis factor binding(GO:0043120)
1.2 13.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.2 3.5 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
1.1 4.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.7 2.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.7 2.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.7 2.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.7 4.9 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.5 2.7 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.5 11.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.5 6.5 GO:0008061 chitin binding(GO:0008061)
0.4 2.6 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.4 1.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.4 2.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.4 2.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.4 40.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 3.1 GO:0004630 phospholipase D activity(GO:0004630)
0.4 22.5 GO:0008146 sulfotransferase activity(GO:0008146)
0.3 1.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.3 1.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 1.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 2.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 3.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 2.8 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.3 0.9 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.3 1.7 GO:0004966 galanin receptor activity(GO:0004966)
0.3 4.1 GO:0030274 LIM domain binding(GO:0030274)
0.2 2.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 11.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 1.9 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 2.5 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.7 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.2 2.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 3.5 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 4.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 1.6 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 1.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 1.7 GO:0050692 DBD domain binding(GO:0050692)
0.2 18.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.2 18.8 GO:0042562 hormone binding(GO:0042562)
0.2 1.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 2.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.1 2.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 9.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 2.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 21.8 GO:0002020 protease binding(GO:0002020)
0.1 0.3 GO:0034632 retinol transporter activity(GO:0034632)
0.1 5.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.5 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 5.3 GO:0050699 WW domain binding(GO:0050699)
0.1 2.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.8 GO:0005522 profilin binding(GO:0005522)
0.1 5.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.3 GO:0035473 lipase binding(GO:0035473)
0.1 2.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 4.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.2 GO:0017166 vinculin binding(GO:0017166)
0.1 3.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 7.6 GO:0005178 integrin binding(GO:0005178)
0.1 4.7 GO:0005518 collagen binding(GO:0005518)
0.1 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 3.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 2.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 1.3 GO:0008483 transaminase activity(GO:0008483)
0.0 2.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 5.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 3.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 5.4 GO:0003924 GTPase activity(GO:0003924)
0.0 10.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 28.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.5 17.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 17.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 4.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 12.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 14.3 PID IL1 PATHWAY IL1-mediated signaling events
0.2 9.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 5.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 12.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 6.8 PID BMP PATHWAY BMP receptor signaling
0.1 29.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 2.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 5.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 4.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 0.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 17.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 3.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 7.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 10.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.9 43.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.8 16.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.7 18.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.7 20.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.5 7.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 16.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 4.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 14.5 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.3 23.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 2.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 4.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 11.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 2.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 4.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 5.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 3.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 2.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 4.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 6.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 3.1 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.1 1.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 3.0 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.2 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 3.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4