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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Clock

Z-value: 0.63

Motif logo

Transcription factors associated with Clock

Gene Symbol Gene ID Gene Info
ENSMUSG00000029238.12 Clock

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Clockmm39_v1_chr5_-_76452365_764523980.325.6e-02Click!

Activity profile of Clock motif

Sorted Z-values of Clock motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Clock

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_22549688 1.98 ENSMUST00000062372.14
ENSMUST00000161356.8
reelin
chrX_+_8137372 1.98 ENSMUST00000127103.8
ENSMUST00000115591.8
solute carrier family 38, member 5
chr1_+_59724108 1.90 ENSMUST00000027174.10
ENSMUST00000190231.7
ENSMUST00000191142.7
ENSMUST00000185772.7
NOP58 ribonucleoprotein
chr2_+_164611812 1.79 ENSMUST00000088248.13
ENSMUST00000001439.7
ubiquitin-conjugating enzyme E2C
chrX_+_8137620 1.75 ENSMUST00000033512.11
solute carrier family 38, member 5
chr15_+_103148824 1.71 ENSMUST00000036004.16
ENSMUST00000087351.9
ENSMUST00000231141.2
heterogeneous nuclear ribonucleoprotein A1
chr2_+_160487801 1.68 ENSMUST00000109468.3
topoisomerase (DNA) I
chrX_+_8137881 1.66 ENSMUST00000115590.2
solute carrier family 38, member 5
chr4_+_123176570 1.64 ENSMUST00000106243.8
ENSMUST00000106241.8
ENSMUST00000080178.13
poly(A) binding protein, cytoplasmic 4
chr18_+_35686424 1.57 ENSMUST00000235679.2
ENSMUST00000235176.2
ENSMUST00000235801.2
ENSMUST00000237592.2
ENSMUST00000237230.2
ENSMUST00000237589.2
small nucleolar RNA host gene 4
small nucleolar RNA host gene 4
chr3_+_51131868 1.44 ENSMUST00000023849.15
ENSMUST00000167780.2
nocturnin
chr4_-_131802561 1.25 ENSMUST00000105970.8
ENSMUST00000105975.8
erythrocyte membrane protein band 4.1
chr4_-_131802606 1.17 ENSMUST00000146021.8
erythrocyte membrane protein band 4.1
chr11_+_68986043 1.16 ENSMUST00000101004.9
period circadian clock 1
chr18_+_42644552 1.13 ENSMUST00000237602.2
ENSMUST00000236088.2
ENSMUST00000025375.15
transcription elongation regulator 1 (CA150)
chr11_+_101207743 1.12 ENSMUST00000151385.2
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr6_-_49191891 1.11 ENSMUST00000031838.9
insulin-like growth factor 2 mRNA binding protein 3
chr1_+_172327812 1.02 ENSMUST00000192460.2
transgelin 2
chr1_-_86286690 0.97 ENSMUST00000185785.2
nucleolin
chr11_-_106679983 0.96 ENSMUST00000129585.8
DEAD box helicase 5
chr17_+_43327412 0.96 ENSMUST00000024708.6
tumor necrosis factor receptor superfamily, member 21
chr1_-_153208477 0.94 ENSMUST00000027752.15
laminin, gamma 1
chr5_-_77099406 0.94 ENSMUST00000140076.2
phosphoribosyl pyrophosphate amidotransferase
chr5_+_146168020 0.93 ENSMUST00000161181.8
ENSMUST00000161652.8
ENSMUST00000031640.15
ENSMUST00000159467.2
cyclin-dependent kinase 8
chr13_-_12355604 0.92 ENSMUST00000168193.8
ENSMUST00000064204.14
actinin alpha 2
chr1_+_172328768 0.91 ENSMUST00000111228.2
transgelin 2
chr19_+_9995557 0.90 ENSMUST00000113161.10
ENSMUST00000238672.2
ENSMUST00000117641.8
RAB3A interacting protein (rabin3)-like 1
chr17_+_35220252 0.88 ENSMUST00000174260.8
valyl-tRNA synthetase
chr11_+_72332167 0.86 ENSMUST00000045633.6
MYB binding protein (P160) 1a
chr11_-_106679671 0.82 ENSMUST00000123339.2
DEAD box helicase 5
chr4_-_133484080 0.81 ENSMUST00000008024.7
AT rich interactive domain 1A (SWI-like)
chr2_+_130116357 0.81 ENSMUST00000136621.9
ENSMUST00000141872.2
NOP56 ribonucleoprotein
chr9_+_14695933 0.79 ENSMUST00000034405.11
ENSMUST00000115632.10
ENSMUST00000147305.2
MRE11A homolog A, double strand break repair nuclease
chr3_-_107992662 0.78 ENSMUST00000078912.7
adenosine monophosphate deaminase 2
chr17_-_45883421 0.75 ENSMUST00000130406.2
heat shock protein 90 alpha (cytosolic), class B member 1
chr15_-_38079089 0.71 ENSMUST00000110336.4
ubiquitin protein ligase E3 component n-recognin 5
chr9_-_14695801 0.70 ENSMUST00000214979.2
ENSMUST00000216037.2
ENSMUST00000214456.2
ankyrin repeat domain 49
chr2_+_14234198 0.67 ENSMUST00000028045.4
mannose receptor, C type 1
chr19_+_9995629 0.65 ENSMUST00000131407.2
RAB3A interacting protein (rabin3)-like 1
chr11_+_101207021 0.64 ENSMUST00000142640.8
ENSMUST00000019470.14
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr17_+_47922497 0.63 ENSMUST00000024778.3
mediator complex subunit 20
chr1_-_181039509 0.62 ENSMUST00000162819.9
ENSMUST00000237749.2
WD repeat domain 26
chr6_+_17463925 0.61 ENSMUST00000115442.8
met proto-oncogene
chr10_+_36850532 0.61 ENSMUST00000019911.14
ENSMUST00000105510.2
histone deacetylase 2
chr17_+_71511642 0.61 ENSMUST00000126681.8
lipin 2
chr5_+_77099229 0.60 ENSMUST00000141687.2
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr4_+_21848039 0.59 ENSMUST00000098238.9
ENSMUST00000108229.2
PNN interacting serine/arginine-rich
chr2_+_18059982 0.59 ENSMUST00000028076.15
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr19_+_46044972 0.59 ENSMUST00000111899.8
ENSMUST00000099392.10
ENSMUST00000062322.11
peroxisome proliferative activated receptor, gamma, coactivator-related 1
chr4_+_32657105 0.59 ENSMUST00000071642.11
ENSMUST00000178134.2
midasin AAA ATPase 1
chr5_+_77122530 0.58 ENSMUST00000101087.10
ENSMUST00000120550.2
signal recognition particle 72
chr17_+_71923210 0.57 ENSMUST00000047086.10
WD repeat domain 43
chr17_+_35219941 0.53 ENSMUST00000087315.14
valyl-tRNA synthetase
chr15_-_44651411 0.53 ENSMUST00000090057.6
ENSMUST00000110269.8
ENSMUST00000228639.2
syntabulin (syntaxin-interacting)
chr17_+_35219998 0.53 ENSMUST00000173584.8
valyl-tRNA synthetase
chr3_+_145281941 0.52 ENSMUST00000199033.5
ENSMUST00000098534.9
ENSMUST00000200574.5
ENSMUST00000196413.5
ENSMUST00000197604.3
zinc finger, HIT type 6
chr2_+_83474779 0.51 ENSMUST00000081591.7
zinc finger CCCH-type containing 15
chr7_-_144493560 0.51 ENSMUST00000093962.5
cyclin D1
chr15_+_81695615 0.51 ENSMUST00000023024.8
thyrotroph embryonic factor
chr16_-_43709968 0.51 ENSMUST00000023387.14
queuine tRNA-ribosyltransferase accessory subunit 2
chr6_+_83142902 0.50 ENSMUST00000077407.12
ENSMUST00000113913.8
ENSMUST00000130212.8
dynactin 1
chr18_-_60981981 0.49 ENSMUST00000177172.8
ENSMUST00000175934.8
ENSMUST00000176630.8
treacle ribosome biogenesis factor 1
chrX_+_35592006 0.47 ENSMUST00000016383.10
LON peptidase N-terminal domain and ring finger 3
chr12_+_8724681 0.45 ENSMUST00000168361.8
ENSMUST00000169750.8
ENSMUST00000163730.8
pumilio RNA-binding family member 2
chr4_-_129636073 0.45 ENSMUST00000066257.6
KH domain containing, RNA binding, signal transduction associated 1
chr4_-_116263183 0.45 ENSMUST00000123072.8
ENSMUST00000144281.2
microtubule associated serine/threonine kinase 2
chr11_+_106107752 0.44 ENSMUST00000021046.6
DEAD box helicase 42
chr6_+_125073108 0.44 ENSMUST00000112390.8
chromodomain helicase DNA binding protein 4
chr1_-_121495623 0.43 ENSMUST00000001724.12
DEAD box helicase 18
chr15_-_102533870 0.43 ENSMUST00000184485.8
ENSMUST00000185070.8
ENSMUST00000184616.8
ENSMUST00000108828.9
activating transcription factor 7
chr5_+_66833434 0.41 ENSMUST00000031131.11
ubiquitin carboxy-terminal hydrolase L1
chr11_-_118181044 0.41 ENSMUST00000106296.9
ENSMUST00000092382.10
ubiquitin specific peptidase 36
chr14_-_118943591 0.41 ENSMUST00000036554.14
ENSMUST00000166646.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr12_+_59178072 0.40 ENSMUST00000176464.8
ENSMUST00000170992.9
ENSMUST00000176322.8
MIA SH3 domain ER export factor 2
chr3_+_135531409 0.40 ENSMUST00000180196.8
solute carrier family 39 (metal ion transporter), member 8
chr11_-_76108316 0.40 ENSMUST00000102500.5
gem nuclear organelle associated protein 4
chr4_+_109263820 0.39 ENSMUST00000124209.8
tetratricopeptide repeat domain 39A
chr3_+_135531834 0.38 ENSMUST00000029810.6
solute carrier family 39 (metal ion transporter), member 8
chr6_+_17463819 0.38 ENSMUST00000140070.8
met proto-oncogene
chr16_+_35590745 0.37 ENSMUST00000231579.2
Hspb associated protein 1
chr4_+_44756553 0.37 ENSMUST00000107824.9
zinc finger, CCHC domain containing 7
chr11_+_106680062 0.36 ENSMUST00000103068.10
ENSMUST00000018516.11
centrosomal protein 95
chr11_+_100751272 0.35 ENSMUST00000107357.4
signal transducer and activator of transcription 5A
chr14_+_30741082 0.34 ENSMUST00000112098.11
ENSMUST00000112095.8
ENSMUST00000112106.8
ENSMUST00000146325.8
polybromo 1
chrX_-_92675719 0.34 ENSMUST00000006856.3
polymerase (DNA directed), alpha 1
chr13_-_76091931 0.34 ENSMUST00000022078.12
ENSMUST00000109606.3
Rho-related BTB domain containing 3
chr11_+_70735751 0.34 ENSMUST00000177731.8
ENSMUST00000108533.10
ENSMUST00000081362.13
ENSMUST00000178245.2
rabaptin, RAB GTPase binding effector protein 1
chr13_-_63712349 0.34 ENSMUST00000192155.6
patched 1
chr11_-_118180895 0.33 ENSMUST00000144153.8
ubiquitin specific peptidase 36
chr2_+_115412148 0.32 ENSMUST00000166472.8
ENSMUST00000110918.3
CDAN1 interacting nuclease 1
chr11_-_51647204 0.32 ENSMUST00000109092.8
ENSMUST00000064297.5
Sec24 related gene family, member A (S. cerevisiae)
chr9_+_107464841 0.32 ENSMUST00000010192.11
interferon-related developmental regulator 2
chr16_+_18695787 0.32 ENSMUST00000120532.9
ENSMUST00000004222.14
histone cell cycle regulator
chr17_-_28705055 0.30 ENSMUST00000233870.2
FK506 binding protein 5
chr4_-_148529187 0.28 ENSMUST00000051633.3
UbiA prenyltransferase domain containing 1
chrX_-_94488394 0.28 ENSMUST00000084535.6
APC membrane recruitment 1
chr12_+_17594795 0.28 ENSMUST00000171737.3
ornithine decarboxylase, structural 1
chr5_+_35156454 0.28 ENSMUST00000114283.8
regulator of G-protein signaling 12
chr1_-_166237341 0.27 ENSMUST00000135673.8
ENSMUST00000169324.8
ENSMUST00000128861.3
pogo transposable element with KRAB domain
chr7_-_29204812 0.27 ENSMUST00000183096.8
ENSMUST00000085809.11
signal-induced proliferation-associated 1 like 3
chr19_-_29790352 0.27 ENSMUST00000099525.5
RAN binding protein 6
chr12_+_59178258 0.26 ENSMUST00000177162.8
MIA SH3 domain ER export factor 2
chr9_+_43978290 0.26 ENSMUST00000034508.14
ubiquitin specific peptidase 2
chr3_+_41519289 0.26 ENSMUST00000168086.7
jade family PHD finger 1
chr11_-_106107132 0.25 ENSMUST00000002043.10
coiled-coil domain containing 47
chr18_+_32970278 0.25 ENSMUST00000053663.11
WD repeat domain 36
chr9_+_40712562 0.24 ENSMUST00000117557.8
heat shock protein 8
chr8_+_91555449 0.23 ENSMUST00000109614.9
chromodomain helicase DNA binding protein 9
chrX_-_36127891 0.23 ENSMUST00000115249.10
ENSMUST00000115248.10
RIKEN cDNA C330007P06 gene
chr5_+_31855394 0.22 ENSMUST00000063813.11
ENSMUST00000071531.12
ENSMUST00000131995.7
ENSMUST00000114507.10
BRISC and BRCA1 A complex member 2
chr12_+_71183622 0.22 ENSMUST00000149564.8
RIKEN cDNA 2700049A03 gene
chr18_+_32970363 0.21 ENSMUST00000166214.9
WD repeat domain 36
chr3_+_135531548 0.21 ENSMUST00000167390.8
solute carrier family 39 (metal ion transporter), member 8
chr2_+_48839505 0.21 ENSMUST00000112745.8
ENSMUST00000112754.8
methyl-CpG binding domain protein 5
chr5_-_108922819 0.20 ENSMUST00000200159.2
ENSMUST00000212212.2
ring finger protein 212
chr1_-_52539395 0.19 ENSMUST00000186764.7
Ngfi-A binding protein 1
chr5_+_120254530 0.18 ENSMUST00000031590.12
RNA binding motif protein 19
chr4_+_132001680 0.18 ENSMUST00000030731.11
ENSMUST00000105963.2
TATA-box binding protein associated factor 12
chr14_+_4230658 0.18 ENSMUST00000225491.2
nuclear receptor subfamily 1, group D, member 2
chr9_+_110162470 0.17 ENSMUST00000198761.5
ENSMUST00000197630.3
SREBF chaperone
chr15_+_80556023 0.17 ENSMUST00000023044.7
family with sequence similarity 83, member F
chr5_+_77099154 0.17 ENSMUST00000031160.16
ENSMUST00000120912.8
ENSMUST00000117536.8
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr19_+_26600820 0.17 ENSMUST00000176584.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_+_127345909 0.16 ENSMUST00000033081.14
F-box and leucine-rich repeat protein 19
chr2_-_118380149 0.16 ENSMUST00000090219.13
BCL2 modifying factor
chr17_-_45884179 0.16 ENSMUST00000165127.8
ENSMUST00000166469.8
ENSMUST00000024739.14
heat shock protein 90 alpha (cytosolic), class B member 1
chr11_-_120238917 0.15 ENSMUST00000106215.11
actin, gamma, cytoplasmic 1
chr11_+_94520567 0.15 ENSMUST00000021239.7
leucine rich repeat containing 59
chr12_-_32000169 0.15 ENSMUST00000176520.8
high mobility group box transcription factor 1
chr5_-_108943211 0.15 ENSMUST00000004943.2
transmembrane p24 trafficking protein 11
chr10_+_69048506 0.14 ENSMUST00000167384.8
Rho-related BTB domain containing 1
chr12_+_69418886 0.14 ENSMUST00000050063.9
ADP-ribosylation factor 6
chr6_+_49296208 0.13 ENSMUST00000055559.8
ENSMUST00000114491.2
coiled-coil domain containing 126
chr4_-_156077061 0.12 ENSMUST00000052185.5
UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
chr2_-_168048984 0.12 ENSMUST00000088001.6
activity-dependent neuroprotective protein
chr14_-_20718337 0.11 ENSMUST00000057090.12
ENSMUST00000117386.2
synaptopodin 2-like
chr7_-_68398989 0.11 ENSMUST00000048068.15
arrestin domain containing 4
chr4_-_124587340 0.10 ENSMUST00000030738.8
UTP11 small subunit processome component
chr3_-_108117754 0.09 ENSMUST00000117784.8
ENSMUST00000119650.8
ENSMUST00000117409.8
ataxin 7-like 2
chr9_-_110483210 0.09 ENSMUST00000196488.5
ENSMUST00000133191.8
ENSMUST00000167320.8
neurobeachin-like 2
chr11_-_51891575 0.09 ENSMUST00000109086.8
ubiquitin-conjugating enzyme E2B
chr9_+_110162345 0.09 ENSMUST00000198976.5
SREBF chaperone
chr16_-_44978986 0.09 ENSMUST00000180636.8
solute carrier family 35, member A5
chr17_-_47922374 0.09 ENSMUST00000024783.9
bystin-like
chr11_+_67689094 0.08 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chr8_-_37081091 0.08 ENSMUST00000033923.14
deleted in liver cancer 1
chr19_+_46045675 0.08 ENSMUST00000126127.8
ENSMUST00000147640.2
peroxisome proliferative activated receptor, gamma, coactivator-related 1
chr15_-_51728893 0.08 ENSMUST00000022925.10
eukaryotic translation initiation factor 3, subunit H
chr17_-_28705082 0.08 ENSMUST00000079413.11
FK506 binding protein 5
chr4_+_44756608 0.08 ENSMUST00000143385.2
zinc finger, CCHC domain containing 7
chr2_+_27405169 0.08 ENSMUST00000113952.10
WD repeat domain 5
chr11_+_74721733 0.07 ENSMUST00000000291.9
max binding protein
chr14_+_30741115 0.06 ENSMUST00000112094.8
ENSMUST00000144009.2
polybromo 1
chr12_-_32000209 0.06 ENSMUST00000176084.2
ENSMUST00000176103.8
ENSMUST00000167458.9
high mobility group box transcription factor 1
chr16_+_43710163 0.05 ENSMUST00000132859.8
ENSMUST00000178400.9
coiled-coil domain containing 191
chr16_-_44978546 0.05 ENSMUST00000114600.2
solute carrier family 35, member A5
chr1_-_186438177 0.04 ENSMUST00000045288.14
transforming growth factor, beta 2
chr19_-_29782907 0.04 ENSMUST00000175726.8
RIKEN cDNA 9930021J03 gene
chr2_-_48839218 0.03 ENSMUST00000090976.10
ENSMUST00000149679.8
origin recognition complex, subunit 4
chr12_+_24701273 0.03 ENSMUST00000020982.7
Kruppel-like factor 11
chr9_+_43978369 0.03 ENSMUST00000177054.8
ubiquitin specific peptidase 2
chr11_-_100650768 0.03 ENSMUST00000107363.3
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr16_+_23247883 0.02 ENSMUST00000038730.7
receptor transporter protein 1
chr9_-_121324744 0.02 ENSMUST00000035120.6
cholecystokinin
chr16_-_44978929 0.02 ENSMUST00000181177.2
solute carrier family 35, member A5
chr9_+_58041300 0.02 ENSMUST00000134955.8
ENSMUST00000147134.8
ENSMUST00000170397.8
stimulated by retinoic acid gene 6
chr7_+_19311212 0.02 ENSMUST00000108453.2
zinc finger protein 296
chr1_-_186437760 0.02 ENSMUST00000195201.2
transforming growth factor, beta 2
chr16_-_33787399 0.00 ENSMUST00000023510.7
uridine monophosphate synthetase
chr2_+_90865958 0.00 ENSMUST00000111445.10
ENSMUST00000111446.10
ENSMUST00000050323.6
receptor-associated protein of the synapse
chr3_+_88439616 0.00 ENSMUST00000172699.2
mex3 RNA binding family member A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.3 2.4 GO:0048254 snoRNA localization(GO:0048254)
0.3 1.9 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.3 0.9 GO:0086097 actin filament uncapping(GO:0051695) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.3 0.9 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.3 5.4 GO:0015816 glycine transport(GO:0015816)
0.3 1.8 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.2 1.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.2 0.8 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.2 1.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 1.2 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 1.7 GO:0006265 DNA topological change(GO:0006265)
0.2 0.7 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.2 1.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 0.9 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.4 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 0.9 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 2.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.9 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 1.5 GO:2000232 regulation of rRNA processing(GO:2000232)
0.1 0.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 1.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.3 GO:0009233 menaquinone metabolic process(GO:0009233)
0.1 1.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.3 GO:0060376 positive regulation of mast cell differentiation(GO:0060376)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272)
0.1 0.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.2 GO:0097212 protein targeting to vacuole involved in autophagy(GO:0071211) lysosomal membrane organization(GO:0097212)
0.1 0.8 GO:0006188 IMP biosynthetic process(GO:0006188)
0.1 0.5 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.2 GO:1904093 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.1 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.4 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.9 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.2 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.0 0.4 GO:0072553 terminal button organization(GO:0072553)
0.0 0.3 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.4 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.5 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.8 GO:0000154 rRNA modification(GO:0000154)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.4 GO:0006855 drug transmembrane transport(GO:0006855) prostaglandin secretion(GO:0032310)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:1905006 positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 1.7 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 1.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.7 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.7 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 1.5 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0001651 dense fibrillar component(GO:0001651)
0.3 2.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 1.8 GO:0008537 proteasome activator complex(GO:0008537)
0.3 0.9 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.2 0.9 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 0.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 1.8 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.8 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.5 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.2 GO:0000125 PCAF complex(GO:0000125)
0.1 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 2.9 GO:0099738 cell cortex region(GO:0099738)
0.0 1.0 GO:0071564 npBAF complex(GO:0071564)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0035500 MH2 domain binding(GO:0035500)
0.6 1.7 GO:0097100 supercoiled DNA binding(GO:0097100)
0.4 5.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 1.9 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.3 2.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 0.9 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 2.4 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.2 0.6 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.2 0.9 GO:0051373 FATZ binding(GO:0051373)
0.2 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 1.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.0 GO:0042134 rRNA primary transcript binding(GO:0042134) DNA topoisomerase binding(GO:0044547)
0.1 0.9 GO:0002135 CTP binding(GO:0002135)
0.1 0.6 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.8 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.1 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.2 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 0.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.9 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.8 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 5.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing