avrg: GSE58827: Dynamics of the Mouse Liver

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
E2f2 Links Ensembl NCBI MGI UniProt	ENSMUSG00000018983.10	E2f2
E2f5 Links Ensembl NCBI MGI UniProt	ENSMUSG00000027552.15	E2f5

Gene	Promoter	Pearson corr. coef.	P-value	Plot
E2f2	mm39_v1_chr4_+_135899678_135899738	0.95	1.6e-18	Click!
E2f5	mm39_v1_chr3_+_14643669_14643756	0.49	2.2e-03	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr4_+_135899678 Show fit	163.15	ENSMUST00000061721.6	E2f2 Links Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 2
chr4_+_134591847 Show fit	122.24	ENSMUST00000030627.8	Rhd Links Ensembl NCBI MGI UniProt Show fit	Rh blood group, D antigen
chr12_+_24758240 Show fit	116.74	ENSMUST00000020980.12	Rrm2 Links Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chr8_+_75836187 Show fit	99.34	ENSMUST00000164309.3 ENSMUST00000212426.2 ENSMUST00000212811.2	Mcm5 Links Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 5
chr5_-_138170077 Show fit	84.28	ENSMUST00000155902.8 ENSMUST00000148879.8	Mcm7 Links Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 7
chr10_-_69188716 Show fit	77.51	ENSMUST00000119827.8 ENSMUST00000020099.13	Cdk1 Links Ensembl NCBI MGI UniProt Show fit	cyclin-dependent kinase 1
chr1_-_128287347 Show fit	76.06	ENSMUST00000190495.2 ENSMUST00000027601.11	Mcm6 Links Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 6
chr12_+_24758968 Show fit	74.99	ENSMUST00000154588.2	Rrm2 Links Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chr12_+_24758724 Show fit	72.61	ENSMUST00000153058.8	Rrm2 Links Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chr13_-_55477535 Show fit	69.86	ENSMUST00000021941.8	Mxd3 Links Ensembl NCBI MGI UniProt Show fit	Max dimerization protein 3
chr6_-_88875646 Show fit	69.30	ENSMUST00000058011.8	Mcm2 Links Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 2
chr17_+_56611313 Show fit	68.35	ENSMUST00000113035.8 ENSMUST00000113039.9 ENSMUST00000142387.2	Uhrf1 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains, 1
chr2_+_72306503 Show fit	60.83	ENSMUST00000102691.11 ENSMUST00000157019.2	Cdca7 Links Ensembl NCBI MGI UniProt Show fit	cell division cycle associated 7
chr7_-_6733411 Show fit	60.29	ENSMUST00000239104.2 ENSMUST00000051209.11	Peg3 Links Ensembl NCBI MGI UniProt Show fit	paternally expressed 3
chr1_-_20890437 Show fit	60.15	ENSMUST00000053266.11	Mcm3 Links Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 3
chr16_-_15455141 Show fit	53.02	ENSMUST00000023353.4	Mcm4 Links Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 4
chr5_-_138170644 Show fit	52.53	ENSMUST00000000505.16	Mcm7 Links Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 7
chr10_-_5755412 Show fit	50.16	ENSMUST00000019907.8	Fbxo5 Links Ensembl NCBI MGI UniProt Show fit	F-box protein 5
chr9_+_109704609 Show fit	48.11	ENSMUST00000094324.8	Cdc25a Links Ensembl NCBI MGI UniProt Show fit	cell division cycle 25A
chr4_+_126450728 Show fit	47.97	ENSMUST00000048391.15	Clspn Links Ensembl NCBI MGI UniProt Show fit	claspin
chr9_-_20864096 Show fit	46.15	ENSMUST00000004202.17	Dnmt1 Links Ensembl NCBI MGI UniProt Show fit	DNA methyltransferase (cytosine-5) 1
chr12_-_69274936 Show fit	45.48	ENSMUST00000221411.2 ENSMUST00000021359.7	Pole2 Links Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr14_-_20438890 Show fit	43.91	ENSMUST00000022345.7	Dnajc9 Links Ensembl NCBI MGI UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C9
chr9_+_64188857 Show fit	42.23	ENSMUST00000215031.2 ENSMUST00000213165.2 ENSMUST00000213289.2 ENSMUST00000216594.2 ENSMUST00000034964.7	Tipin Links Ensembl NCBI MGI UniProt Show fit	timeless interacting protein
chr2_-_28511941 Show fit	40.30	ENSMUST00000028156.8 ENSMUST00000164290.8	Gfi1b Links Ensembl NCBI MGI UniProt Show fit	growth factor independent 1B
chr9_+_44245981 Show fit	37.82	ENSMUST00000052686.4	H2ax Links Ensembl NCBI MGI UniProt Show fit	H2A.X variant histone
chr2_+_118943274 Show fit	37.02	ENSMUST00000140939.8 ENSMUST00000028795.10	Rad51 Links Ensembl NCBI MGI UniProt Show fit	RAD51 recombinase
chr2_-_113678999 Show fit	35.55	ENSMUST00000102545.8 ENSMUST00000110948.8	Arhgap11a Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 11A
chr13_-_22017677 Show fit	35.35	ENSMUST00000081342.7	H2ac24 Links Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 24
chr4_+_134195631 Show fit	34.79	ENSMUST00000030636.11 ENSMUST00000127279.8 ENSMUST00000105867.8	Stmn1 Links Ensembl NCBI MGI UniProt Show fit	stathmin 1
chr13_-_24945844 Show fit	33.72	ENSMUST00000006898.10 ENSMUST00000110382.9	Gmnn Links Ensembl NCBI MGI UniProt Show fit	geminin
chr13_-_47259652 Show fit	33.07	ENSMUST00000021807.13 ENSMUST00000135278.8	Dek Links Ensembl NCBI MGI UniProt Show fit	DEK proto-oncogene (DNA binding)
chr5_+_110434172 Show fit	30.91	ENSMUST00000007296.12 ENSMUST00000112482.2	Pole Links Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), epsilon
chr5_+_88912855 Show fit	29.55	ENSMUST00000031311.10	Dck Links Ensembl NCBI MGI UniProt Show fit	deoxycytidine kinase
chr6_+_4747298 Show fit	28.87	ENSMUST00000166678.2 ENSMUST00000176204.8	Peg10 Links Ensembl NCBI MGI UniProt Show fit	paternally expressed 10
chr13_-_24945423 Show fit	28.81	ENSMUST00000176890.8 ENSMUST00000175689.8	Gmnn Links Ensembl NCBI MGI UniProt Show fit	geminin
chrX_-_7940959 Show fit	28.26	ENSMUST00000115636.4 ENSMUST00000115638.10	Suv39h1 Links Ensembl NCBI MGI UniProt Show fit	suppressor of variegation 3-9 1
chr12_-_4924341 Show fit	27.03	ENSMUST00000137337.8 ENSMUST00000045921.14	Mfsd2b Links Ensembl NCBI MGI UniProt Show fit	major facilitator superfamily domain containing 2B
chr4_-_133695264 Show fit	26.90	ENSMUST00000102553.11	Hmgn2 Links Ensembl NCBI MGI UniProt Show fit	high mobility group nucleosomal binding domain 2
chr2_-_157046386 Show fit	26.60	ENSMUST00000029170.8	Rbl1 Links Ensembl NCBI MGI UniProt Show fit	RB transcriptional corepressor like 1
chr17_+_56610396 Show fit	26.54	ENSMUST00000113038.8	Uhrf1 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains, 1
chr18_+_10617773 Show fit	26.38	ENSMUST00000002551.5 ENSMUST00000234207.2	Snrpd1 Links Ensembl NCBI MGI UniProt Show fit	small nuclear ribonucleoprotein D1
chr9_+_65797519 Show fit	26.37	ENSMUST00000045802.7	Pclaf Links Ensembl NCBI MGI UniProt Show fit	PCNA clamp associated factor
chr9_+_122780111 Show fit	25.29	ENSMUST00000040717.7 ENSMUST00000214652.2 ENSMUST00000217401.2	Kif15 Links Ensembl NCBI MGI UniProt Show fit	kinesin family member 15
chr7_-_48531344 Show fit	25.25	ENSMUST00000119223.2	E2f8 Links Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 8
chr2_+_150751475 Show fit	25.22	ENSMUST00000028948.5	Gins1 Links Ensembl NCBI MGI UniProt Show fit	GINS complex subunit 1 (Psf1 homolog)
chr6_-_4747157 Show fit	24.57	ENSMUST00000126151.8 ENSMUST00000115577.9 ENSMUST00000101677.9 ENSMUST00000115579.8 ENSMUST00000004750.15	Sgce Links Ensembl NCBI MGI UniProt Show fit	sarcoglycan, epsilon
chr17_+_29020064 Show fit	24.11	ENSMUST00000004985.11	Brpf3 Links Ensembl NCBI MGI UniProt Show fit	bromodomain and PHD finger containing, 3
chr1_-_86287080 Show fit	23.97	ENSMUST00000027438.8	Ncl Links Ensembl NCBI MGI UniProt Show fit	nucleolin
chr4_+_114857348 Show fit	23.09	ENSMUST00000030490.13	Stil Links Ensembl NCBI MGI UniProt Show fit	Scl/Tal1 interrupting locus
chr8_+_13388745 Show fit	22.58	ENSMUST00000209885.2 ENSMUST00000209396.2	Tfdp1 Links Ensembl NCBI MGI UniProt Show fit	transcription factor Dp 1
chr2_-_154411765 Show fit	22.51	ENSMUST00000103145.11	E2f1 Links Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 1
chr7_+_109721230 Show fit	22.45	ENSMUST00000033326.10	Wee1 Links Ensembl NCBI MGI UniProt Show fit	WEE 1 homolog 1 (S. pombe)
chrX_+_20570145 Show fit	22.38	ENSMUST00000033383.3	Usp11 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 11
chr8_-_34578880 Show fit	22.37	ENSMUST00000080152.5	Gm10131 Links Ensembl NCBI MGI UniProt Show fit	predicted pseudogene 10131
chr9_-_21202545 Show fit	21.75	ENSMUST00000215619.2	Cdkn2d Links Ensembl NCBI MGI UniProt Show fit	cyclin dependent kinase inhibitor 2D
chr14_-_73563212 Show fit	21.42	ENSMUST00000022701.7	Rb1 Links Ensembl NCBI MGI UniProt Show fit	RB transcriptional corepressor 1
chr7_-_48530777 Show fit	21.18	ENSMUST00000058745.15	E2f8 Links Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 8
chr2_-_113678945 Show fit	21.08	ENSMUST00000110949.9	Arhgap11a Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 11A
chr7_-_19093383 Show fit	20.81	ENSMUST00000047036.10	Cd3eap Links Ensembl NCBI MGI UniProt Show fit	CD3E antigen, epsilon polypeptide associated protein
chr12_-_11315755 Show fit	20.77	ENSMUST00000166117.4 ENSMUST00000219600.2 ENSMUST00000218487.2	Gen1 Links Ensembl NCBI MGI UniProt Show fit	GEN1, Holliday junction 5' flap endonuclease
chr6_-_47571901 Show fit	20.56	ENSMUST00000081721.13 ENSMUST00000114618.8 ENSMUST00000114616.8	Ezh2 Links Ensembl NCBI MGI UniProt Show fit	enhancer of zeste 2 polycomb repressive complex 2 subunit
chr7_-_45045097 Show fit	20.53	ENSMUST00000211121.2 ENSMUST00000074575.11	Snrnp70 Links Ensembl NCBI MGI UniProt Show fit	small nuclear ribonucleoprotein 70 (U1)
chr19_-_10181243 Show fit	20.26	ENSMUST00000142241.2 ENSMUST00000116542.9 ENSMUST00000025651.6 ENSMUST00000156291.2	Fen1 Links Ensembl NCBI MGI UniProt Show fit	flap structure specific endonuclease 1
chr13_-_22227114 Show fit	20.01	ENSMUST00000091741.6	H2ac11 Links Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 11
chr9_-_21202353 Show fit	19.91	ENSMUST00000086374.8	Cdkn2d Links Ensembl NCBI MGI UniProt Show fit	cyclin dependent kinase inhibitor 2D
chr17_+_23945310 Show fit	19.89	ENSMUST00000024701.9	Pkmyt1 Links Ensembl NCBI MGI UniProt Show fit	protein kinase, membrane associated tyrosine/threonine 1
chrX_-_138772383 Show fit	19.71	ENSMUST00000033811.14 ENSMUST00000087401.12	Morc4 Links Ensembl NCBI MGI UniProt Show fit	microrchidia 4
chr17_-_23959334 Show fit	19.56	ENSMUST00000024702.5	Paqr4 Links Ensembl NCBI MGI UniProt Show fit	progestin and adipoQ receptor family member IV
chr4_-_132570421 Show fit	19.09	ENSMUST00000105919.2 ENSMUST00000030702.14	Ppp1r8 Links Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory subunit 8
chr11_+_98798627 Show fit	18.72	ENSMUST00000092706.13	Cdc6 Links Ensembl NCBI MGI UniProt Show fit	cell division cycle 6
chr12_+_116369017 Show fit	18.43	ENSMUST00000084828.5 ENSMUST00000222469.2 ENSMUST00000221114.2 ENSMUST00000221970.2	Ncapg2 Links Ensembl NCBI MGI UniProt Show fit	non-SMC condensin II complex, subunit G2
chr9_-_21202693 Show fit	18.23	ENSMUST00000213407.2	Cdkn2d Links Ensembl NCBI MGI UniProt Show fit	cyclin dependent kinase inhibitor 2D
chr2_-_154411640 Show fit	18.10	ENSMUST00000000894.6	E2f1 Links Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 1
chr15_-_9140403 Show fit	17.99	ENSMUST00000096482.10	Skp2 Links Ensembl NCBI MGI UniProt Show fit	S-phase kinase-associated protein 2
chr2_-_132095146 Show fit	17.95	ENSMUST00000028817.7	Pcna Links Ensembl NCBI MGI UniProt Show fit	proliferating cell nuclear antigen
chr17_+_29709723 Show fit	17.61	ENSMUST00000024811.9	Pim1 Links Ensembl NCBI MGI UniProt Show fit	proviral integration site 1
chr18_-_64622092 Show fit	17.47	ENSMUST00000235766.3 ENSMUST00000025484.9 ENSMUST00000237502.2 ENSMUST00000236586.3	Fech Links Ensembl NCBI MGI UniProt Show fit	ferrochelatase
chr6_+_51447613 Show fit	17.46	ENSMUST00000114445.8 ENSMUST00000114446.8 ENSMUST00000141711.3	Cbx3 Links Ensembl NCBI MGI UniProt Show fit	chromobox 3
chr15_-_57998443 Show fit	17.41	ENSMUST00000038194.5	Atad2 Links Ensembl NCBI MGI UniProt Show fit	ATPase family, AAA domain containing 2
chr6_-_4747066 Show fit	17.38	ENSMUST00000090686.11 ENSMUST00000133306.8	Sgce Links Ensembl NCBI MGI UniProt Show fit	sarcoglycan, epsilon
chr10_+_110581293 Show fit	17.37	ENSMUST00000174857.8 ENSMUST00000073781.12 ENSMUST00000173471.8 ENSMUST00000173634.2	E2f7 Links Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 7
chr7_+_102090892 Show fit	17.36	ENSMUST00000033283.10	Rrm1 Links Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M1
chr6_+_4747356 Show fit	16.95	ENSMUST00000176551.3	Peg10 Links Ensembl NCBI MGI UniProt Show fit	paternally expressed 10
chrX_+_134894573 Show fit	16.89	ENSMUST00000058119.9	Arxes2 Links Ensembl NCBI MGI UniProt Show fit	adipocyte-related X-chromosome expressed sequence 2
chr13_+_22227359 Show fit	16.86	ENSMUST00000110452.2	H2bc11 Links Ensembl NCBI MGI UniProt Show fit	H2B clustered histone 11
chr11_+_79980210 Show fit	16.78	ENSMUST00000017694.7 ENSMUST00000108239.7	Atad5 Links Ensembl NCBI MGI UniProt Show fit	ATPase family, AAA domain containing 5
chr17_+_56610321 Show fit	16.72	ENSMUST00000001258.15	Uhrf1 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains, 1
chr2_-_113678616 Show fit	15.72	ENSMUST00000110947.2	Arhgap11a Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 11A
chr9_+_103182352 Show fit	15.70	ENSMUST00000035164.10	Topbp1 Links Ensembl NCBI MGI UniProt Show fit	topoisomerase (DNA) II binding protein 1
chr9_-_14292453 Show fit	15.66	ENSMUST00000167549.2	Endod1 Links Ensembl NCBI MGI UniProt Show fit	endonuclease domain containing 1
chr1_-_191307648 Show fit	15.56	ENSMUST00000027933.11	Dtl Links Ensembl NCBI MGI UniProt Show fit	denticleless E3 ubiquitin protein ligase
chr8_-_54091980 Show fit	15.08	ENSMUST00000047768.11	Neil3 Links Ensembl NCBI MGI UniProt Show fit	nei like 3 (E. coli)
chr5_+_143846782 Show fit	14.66	ENSMUST00000148011.8 ENSMUST00000110709.7	Pms2 Links Ensembl NCBI MGI UniProt Show fit	PMS1 homolog2, mismatch repair system component
chrX_-_92675719 Show fit	14.54	ENSMUST00000006856.3	Pola1 Links Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), alpha 1
chr6_+_51447490 Show fit	14.26	ENSMUST00000031862.14	Cbx3 Links Ensembl NCBI MGI UniProt Show fit	chromobox 3
chr15_-_54953819 Show fit	14.15	ENSMUST00000110231.2 ENSMUST00000023059.13	Dscc1 Links Ensembl NCBI MGI UniProt Show fit	DNA replication and sister chromatid cohesion 1
chr10_+_128067934 Show fit	14.07	ENSMUST00000055539.11 ENSMUST00000105244.8 ENSMUST00000105243.9	Timeless Links Ensembl NCBI MGI UniProt Show fit	timeless circadian clock 1
chr7_-_44198157 Show fit	13.92	ENSMUST00000145956.2 ENSMUST00000049343.15	Pold1 Links Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), delta 1, catalytic subunit
chr8_-_121316043 Show fit	13.58	ENSMUST00000034278.6	Gins2 Links Ensembl NCBI MGI UniProt Show fit	GINS complex subunit 2 (Psf2 homolog)
chr4_-_133694543 Show fit	13.29	ENSMUST00000123234.8	Hmgn2 Links Ensembl NCBI MGI UniProt Show fit	high mobility group nucleosomal binding domain 2
chr11_+_58839716 Show fit	13.03	ENSMUST00000078267.5	H2bu2 Links Ensembl NCBI MGI UniProt Show fit	H2B.U histone 2
chr7_-_99770653 Show fit	12.93	ENSMUST00000208670.2 ENSMUST00000032969.14	Pold3 Links Ensembl NCBI MGI UniProt Show fit	polymerase (DNA-directed), delta 3, accessory subunit
chrX_-_72502595 Show fit	12.78	ENSMUST00000033737.15 ENSMUST00000077243.5	Haus7 Links Ensembl NCBI MGI UniProt Show fit	HAUS augmin-like complex, subunit 7
chr19_+_46064302 Show fit	12.46	ENSMUST00000165017.2 ENSMUST00000223741.2 ENSMUST00000225780.2	Nolc1 Links Ensembl NCBI MGI UniProt Show fit	nucleolar and coiled-body phosphoprotein 1
chr8_+_85598734 Show fit	12.41	ENSMUST00000170296.2 ENSMUST00000136026.8	Syce2 Links Ensembl NCBI MGI UniProt Show fit	synaptonemal complex central element protein 2
chr4_+_140428777 Show fit	12.40	ENSMUST00000138808.8 ENSMUST00000038893.6	Rcc2 Links Ensembl NCBI MGI UniProt Show fit	regulator of chromosome condensation 2
chr6_+_113508636 Show fit	12.37	ENSMUST00000036340.12 ENSMUST00000204827.3	Fancd2 Links Ensembl NCBI MGI UniProt Show fit	Fanconi anemia, complementation group D2
chrX_+_134786600 Show fit	12.18	ENSMUST00000180025.8 ENSMUST00000148374.8 ENSMUST00000068755.14	Bhlhb9 Links Ensembl NCBI MGI UniProt Show fit	basic helix-loop-helix domain containing, class B9
chr8_-_12722099 Show fit	12.07	ENSMUST00000000776.15	Tubgcp3 Links Ensembl NCBI MGI UniProt Show fit	tubulin, gamma complex associated protein 3
chr2_-_169984593 Show fit	11.91	ENSMUST00000109155.8	Zfp217 Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein 217
chr6_+_51447317 Show fit	11.81	ENSMUST00000094623.10	Cbx3 Links Ensembl NCBI MGI UniProt Show fit	chromobox 3
chr3_-_127346882 Show fit	11.70	ENSMUST00000197668.2 ENSMUST00000029588.10	Larp7 Links Ensembl NCBI MGI UniProt Show fit	La ribonucleoprotein domain family, member 7
chr19_+_53588808 Show fit	11.68	ENSMUST00000025930.10	Smc3 Links Ensembl NCBI MGI UniProt Show fit	structural maintenance of chromosomes 3
chr19_-_6014210 Show fit	11.51	ENSMUST00000025752.15 ENSMUST00000165143.3	Pola2 Links Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), alpha 2
chr4_+_132495636 Show fit	11.35	ENSMUST00000102561.11	Rpa2 Links Ensembl NCBI MGI UniProt Show fit	replication protein A2
chr16_-_18630365 Show fit	10.98	ENSMUST00000096990.10	Cdc45 Links Ensembl NCBI MGI UniProt Show fit	cell division cycle 45
chr9_-_21003268 Show fit	10.89	ENSMUST00000115487.3	Raver1 Links Ensembl NCBI MGI UniProt Show fit	ribonucleoprotein, PTB-binding 1
chr10_+_80634488 Show fit	10.88	ENSMUST00000151928.8	Sf3a2 Links Ensembl NCBI MGI UniProt Show fit	splicing factor 3a, subunit 2
chr13_+_21994588 Show fit	10.74	ENSMUST00000091745.6	H2ac23 Links Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 23
chr18_+_56840813 Show fit	10.58	ENSMUST00000025486.9	Lmnb1 Links Ensembl NCBI MGI UniProt Show fit	lamin B1
chr15_-_9140460 Show fit	10.52	ENSMUST00000110585.10	Skp2 Links Ensembl NCBI MGI UniProt Show fit	S-phase kinase-associated protein 2
chr8_+_69333143 Show fit	10.34	ENSMUST00000015712.15	Lpl Links Ensembl NCBI MGI UniProt Show fit	lipoprotein lipase
chr5_+_45827249 Show fit	10.27	ENSMUST00000117396.3	Ncapg Links Ensembl NCBI MGI UniProt Show fit	non-SMC condensin I complex, subunit G
chr4_-_133695204 Show fit	10.27	ENSMUST00000100472.10 ENSMUST00000136327.2	Hmgn2 Links Ensembl NCBI MGI UniProt Show fit	high mobility group nucleosomal binding domain 2
chr1_+_175708341 Show fit	10.23	ENSMUST00000195196.6 ENSMUST00000194306.6 ENSMUST00000193822.6	Exo1 Links Ensembl NCBI MGI UniProt Show fit	exonuclease 1
chr5_+_75735576 Show fit	10.21	ENSMUST00000144270.8 ENSMUST00000005815.7	Kit Links Ensembl NCBI MGI UniProt Show fit	KIT proto-oncogene receptor tyrosine kinase
chr17_-_71782296 Show fit	10.13	ENSMUST00000127430.2	Smchd1 Links Ensembl NCBI MGI UniProt Show fit	SMC hinge domain containing 1
chr7_-_99770280 Show fit	10.07	ENSMUST00000208184.2	Pold3 Links Ensembl NCBI MGI UniProt Show fit	polymerase (DNA-directed), delta 3, accessory subunit
chr7_-_45044606 Show fit	10.06	ENSMUST00000209858.2	Snrnp70 Links Ensembl NCBI MGI UniProt Show fit	small nuclear ribonucleoprotein 70 (U1)
chr15_+_61857226 Show fit	9.98	ENSMUST00000161976.8 ENSMUST00000022971.8	Myc Links Ensembl NCBI MGI UniProt Show fit	myelocytomatosis oncogene
chr8_-_123404811 Show fit	9.97	ENSMUST00000006525.14 ENSMUST00000064674.13	Cbfa2t3 Links Ensembl NCBI MGI UniProt Show fit	CBFA2/RUNX1 translocation partner 3
chr1_-_93729562 Show fit	9.89	ENSMUST00000112890.3	Dtymk Links Ensembl NCBI MGI UniProt Show fit	deoxythymidylate kinase
chr5_+_114268425 Show fit	9.85	ENSMUST00000031587.13	Ung Links Ensembl NCBI MGI UniProt Show fit	uracil DNA glycosylase
chr15_+_61857390 Show fit	9.84	ENSMUST00000159327.2 ENSMUST00000167731.8	Myc Links Ensembl NCBI MGI UniProt Show fit	myelocytomatosis oncogene
chr19_-_6014159 Show fit	9.80	ENSMUST00000235224.2	Pola2 Links Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), alpha 2
chr13_-_47259266 Show fit	9.64	ENSMUST00000129352.3	Dek Links Ensembl NCBI MGI UniProt Show fit	DEK proto-oncogene (DNA binding)
chr8_-_106434565 Show fit	9.63	ENSMUST00000013299.11	Enkd1 Links Ensembl NCBI MGI UniProt Show fit	enkurin domain containing 1
chr2_+_91480460 Show fit	9.60	ENSMUST00000111331.9	Arhgap1 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 1
chr10_-_21036792 Show fit	9.46	ENSMUST00000188495.8	Myb Links Ensembl NCBI MGI UniProt Show fit	myeloblastosis oncogene
chr11_+_85202058 Show fit	9.30	ENSMUST00000020835.16	Ppm1d Links Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1D magnesium-dependent, delta isoform
chr6_-_8259098 Show fit	9.16	ENSMUST00000012627.5	Rpa3 Links Ensembl NCBI MGI UniProt Show fit	replication protein A3
chr5_+_137743992 Show fit	9.15	ENSMUST00000100540.10	Tsc22d4 Links Ensembl NCBI MGI UniProt Show fit	TSC22 domain family, member 4
chr6_+_4505493 Show fit	9.13	ENSMUST00000031668.10	Col1a2 Links Ensembl NCBI MGI UniProt Show fit	collagen, type I, alpha 2
chrX_-_156275231 Show fit	8.99	ENSMUST00000112529.8	Sms Links Ensembl NCBI MGI UniProt Show fit	spermine synthase
chr5_+_137744228 Show fit	8.92	ENSMUST00000100539.10	Tsc22d4 Links Ensembl NCBI MGI UniProt Show fit	TSC22 domain family, member 4
chr10_-_21036824 Show fit	8.72	ENSMUST00000020158.9	Myb Links Ensembl NCBI MGI UniProt Show fit	myeloblastosis oncogene
chr11_+_87938626 Show fit	8.70	ENSMUST00000107920.10	Srsf1 Links Ensembl NCBI MGI UniProt Show fit	serine and arginine-rich splicing factor 1
chr8_-_79235505 Show fit	8.66	ENSMUST00000211719.2 ENSMUST00000049245.10	Rbmxl1 Links Ensembl NCBI MGI UniProt Show fit	RNA binding motif protein, X-linked like-1
chr15_-_81756076 Show fit	8.40	ENSMUST00000023117.10	Phf5a Links Ensembl NCBI MGI UniProt Show fit	PHD finger protein 5A
chr1_+_86454511 Show fit	8.34	ENSMUST00000188533.2	Ptma Links Ensembl NCBI MGI UniProt Show fit	prothymosin alpha
chrX_+_49930311 Show fit	8.32	ENSMUST00000114887.9	Stk26 Links Ensembl NCBI MGI UniProt Show fit	serine/threonine kinase 26
chr15_-_97991114 Show fit	8.30	ENSMUST00000180657.2	Senp1 Links Ensembl NCBI MGI UniProt Show fit	SUMO1/sentrin specific peptidase 1
chr2_+_91480513 Show fit	8.18	ENSMUST00000090614.11	Arhgap1 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 1
chr11_-_87295292 Show fit	8.11	ENSMUST00000067692.13	Rad51c Links Ensembl NCBI MGI UniProt Show fit	RAD51 paralog C
chr14_-_76248274 Show fit	7.96	ENSMUST00000088922.5	Gtf2f2 Links Ensembl NCBI MGI UniProt Show fit	general transcription factor IIF, polypeptide 2
chr1_+_86454431 Show fit	7.90	ENSMUST00000045897.15 ENSMUST00000186255.7 ENSMUST00000188699.7	Ptma Links Ensembl NCBI MGI UniProt Show fit	prothymosin alpha
chr11_+_87938128 Show fit	7.82	ENSMUST00000139129.9	Srsf1 Links Ensembl NCBI MGI UniProt Show fit	serine and arginine-rich splicing factor 1
chr10_-_128361731 Show fit	7.81	ENSMUST00000026427.8	Esyt1 Links Ensembl NCBI MGI UniProt Show fit	extended synaptotagmin-like protein 1
chr2_-_125348305 Show fit	7.79	ENSMUST00000028633.13	Fbn1 Links Ensembl NCBI MGI UniProt Show fit	fibrillin 1
chr10_+_7543260 Show fit	7.77	ENSMUST00000040135.9	Nup43 Links Ensembl NCBI MGI UniProt Show fit	nucleoporin 43
chr12_-_75678092 Show fit	7.74	ENSMUST00000238938.2	Rplp2-ps1 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein, large P2, pseudogene 1
chr4_-_43010225 Show fit	7.73	ENSMUST00000030165.5	Fancg Links Ensembl NCBI MGI UniProt Show fit	Fanconi anemia, complementation group G
chrX_+_41239548 Show fit	7.67	ENSMUST00000069619.14	Stag2 Links Ensembl NCBI MGI UniProt Show fit	stromal antigen 2
chr13_+_21900554 Show fit	7.64	ENSMUST00000070124.5	H2ac13 Links Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 13
chr4_+_114857370 Show fit	7.62	ENSMUST00000129957.8	Stil Links Ensembl NCBI MGI UniProt Show fit	Scl/Tal1 interrupting locus
chr13_+_22220000 Show fit	7.56	ENSMUST00000110455.4	H2bc12 Links Ensembl NCBI MGI UniProt Show fit	H2B clustered histone 12
chr9_-_13738304 Show fit	7.51	ENSMUST00000148086.8 ENSMUST00000034398.12	Cep57 Links Ensembl NCBI MGI UniProt Show fit	centrosomal protein 57
chr13_-_23929490 Show fit	7.46	ENSMUST00000091752.5	H3c3 Links Ensembl NCBI MGI UniProt Show fit	H3 clustered histone 3
chrX_+_100683662 Show fit	7.42	ENSMUST00000119299.8 ENSMUST00000044475.5	Ogt Links Ensembl NCBI MGI UniProt Show fit	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr9_-_108329576 Show fit	7.40	ENSMUST00000035232.13 ENSMUST00000195435.6	Klhdc8b Links Ensembl NCBI MGI UniProt Show fit	kelch domain containing 8B
chr17_-_28705055 Show fit	7.39	ENSMUST00000233870.2	Fkbp5 Links Ensembl NCBI MGI UniProt Show fit	FK506 binding protein 5
chr13_-_22219738 Show fit	7.16	ENSMUST00000091742.6	H2ac12 Links Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 12
chr1_-_38168697 Show fit	7.00	ENSMUST00000027251.12	Rev1 Links Ensembl NCBI MGI UniProt Show fit	REV1, DNA directed polymerase
chr8_+_96360081 Show fit	6.88	ENSMUST00000034094.11 ENSMUST00000212434.2	Gins3 Links Ensembl NCBI MGI UniProt Show fit	GINS complex subunit 3 (Psf3 homolog)
chr11_+_79883885 Show fit	6.85	ENSMUST00000163272.2 ENSMUST00000017692.15	Suz12 Links Ensembl NCBI MGI UniProt Show fit	SUZ12 polycomb repressive complex 2 subunit
chr14_+_79689230 Show fit	6.83	ENSMUST00000100359.3 ENSMUST00000226192.2	Kbtbd6 Links Ensembl NCBI MGI UniProt Show fit	kelch repeat and BTB (POZ) domain containing 6
chr10_-_60055082 Show fit	6.79	ENSMUST00000135158.9	Chst3 Links Ensembl NCBI MGI UniProt Show fit	carbohydrate sulfotransferase 3
chr13_-_58550290 Show fit	6.76	ENSMUST00000043269.14 ENSMUST00000177060.8 ENSMUST00000224182.2 ENSMUST00000176207.8	Hnrnpk Links Ensembl NCBI MGI UniProt Show fit	heterogeneous nuclear ribonucleoprotein K
chr16_+_76810588 Show fit	6.56	ENSMUST00000239066.2 ENSMUST00000023580.8	Usp25 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 25
chr10_+_128067964 Show fit	6.55	ENSMUST00000125289.8 ENSMUST00000105242.8	Timeless Links Ensembl NCBI MGI UniProt Show fit	timeless circadian clock 1
chr17_-_28705082 Show fit	6.50	ENSMUST00000079413.11	Fkbp5 Links Ensembl NCBI MGI UniProt Show fit	FK506 binding protein 5
chr19_+_46064409 Show fit	6.49	ENSMUST00000223728.2 ENSMUST00000235620.2	Nolc1 Links Ensembl NCBI MGI UniProt Show fit	nucleolar and coiled-body phosphoprotein 1
chr16_-_18066591 Show fit	6.47	ENSMUST00000115645.10	Ranbp1 Links Ensembl NCBI MGI UniProt Show fit	RAN binding protein 1
chr8_+_106363141 Show fit	6.41	ENSMUST00000005841.16	Ctcf Links Ensembl NCBI MGI UniProt Show fit	CCCTC-binding factor
chr3_-_95125002 Show fit	6.40	ENSMUST00000107209.8	Gabpb2 Links Ensembl NCBI MGI UniProt Show fit	GA repeat binding protein, beta 2
chr3_-_95125190 Show fit	6.27	ENSMUST00000136139.8	Gabpb2 Links Ensembl NCBI MGI UniProt Show fit	GA repeat binding protein, beta 2
chr5_-_143846600 Show fit	6.20	ENSMUST00000031613.11 ENSMUST00000100483.3	Aimp2 Links Ensembl NCBI MGI UniProt Show fit	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr3_+_96011810 Show fit	6.06	ENSMUST00000132980.8 ENSMUST00000138206.8 ENSMUST00000090785.9 ENSMUST00000035519.12	Otud7b Links Ensembl NCBI MGI UniProt Show fit	OTU domain containing 7B
chr3_+_116388600 Show fit	6.05	ENSMUST00000198386.5 ENSMUST00000198311.5 ENSMUST00000197335.2	Sass6 Links Ensembl NCBI MGI UniProt Show fit	SAS-6 centriolar assembly protein
chr18_+_31922173 Show fit	6.01	ENSMUST00000025106.5 ENSMUST00000234146.2	Polr2d Links Ensembl NCBI MGI UniProt Show fit	polymerase (RNA) II (DNA directed) polypeptide D
chr19_+_46064437 Show fit	5.96	ENSMUST00000223683.2	Nolc1 Links Ensembl NCBI MGI UniProt Show fit	nucleolar and coiled-body phosphoprotein 1
chr7_-_125995884 Show fit	5.94	ENSMUST00000075671.5	Nfatc2ip Links Ensembl NCBI MGI UniProt Show fit	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
chr13_-_21937997 Show fit	5.86	ENSMUST00000074752.4	H2ac15 Links Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 15
chr11_+_87938519 Show fit	5.79	ENSMUST00000079866.11	Srsf1 Links Ensembl NCBI MGI UniProt Show fit	serine and arginine-rich splicing factor 1
chr3_+_97920819 Show fit	5.79	ENSMUST00000079812.8	Notch2 Links Ensembl NCBI MGI UniProt Show fit	notch 2
chr16_-_22084700 Show fit	5.78	ENSMUST00000161286.8	Tra2b Links Ensembl NCBI MGI UniProt Show fit	transformer 2 beta
chrX_+_47430221 Show fit	5.76	ENSMUST00000136348.8	Bcorl1 Links Ensembl NCBI MGI UniProt Show fit	BCL6 co-repressor-like 1
chr1_+_183078851 Show fit	5.75	ENSMUST00000193625.2	Aida Links Ensembl NCBI MGI UniProt Show fit	axin interactor, dorsalization associated
chr13_+_21938258 Show fit	5.71	ENSMUST00000091709.3	H2bc15 Links Ensembl NCBI MGI UniProt Show fit	H2B clustered histone 15

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
31.0	372.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
30.6	122.2	GO:0072488	ammonium transmembrane transport(GO:0072488)
25.5	203.8	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
21.4	21.4	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
21.3	63.8	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
16.7	50.2	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
15.9	63.4	GO:0006272	leading strand elongation(GO:0006272)
13.9	13.9	GO:0045004	DNA replication proofreading(GO:0045004)
12.7	291.6	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
11.5	46.1	GO:0090309	C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
10.4	52.2	GO:0042276	error-prone translesion synthesis(GO:0042276)
9.3	111.6	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
8.4	42.2	GO:0048478	replication fork protection(GO:0048478)
8.1	64.8	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
6.9	20.6	GO:0071707	immunoglobulin heavy chain V-D-J recombination(GO:0071707)
6.8	225.7	GO:0006270	DNA replication initiation(GO:0006270)
6.6	72.8	GO:0090166	Golgi disassembly(GO:0090166)
6.0	6.0	GO:0031990	mRNA export from nucleus in response to heat stress(GO:0031990)
5.9	29.6	GO:0046125	pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
5.8	40.3	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
5.6	44.4	GO:0044838	cell quiescence(GO:0044838)
5.0	34.8	GO:0070495	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
5.0	19.8	GO:0046722	lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
4.3	77.5	GO:0033280	response to vitamin D(GO:0033280)
4.2	41.9	GO:0019985	translesion synthesis(GO:0019985)
4.1	12.4	GO:0072356	chromosome passenger complex localization to kinetochore(GO:0072356)
4.1	20.6	GO:1904975	response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
3.8	23.0	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
3.7	25.6	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
3.5	17.5	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
3.4	10.1	GO:0060821	inactivation of X chromosome by DNA methylation(GO:0060821)
3.4	20.3	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
3.3	9.8	GO:0006285	base-excision repair, AP site formation(GO:0006285)
3.2	25.2	GO:1902969	mitotic DNA replication(GO:1902969)
3.0	9.0	GO:0006597	spermine biosynthetic process(GO:0006597)
3.0	17.8	GO:1903336	endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
2.9	5.8	GO:1990705	cholangiocyte proliferation(GO:1990705)
2.8	14.1	GO:0034421	post-translational protein acetylation(GO:0034421)
2.7	18.6	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
2.6	10.6	GO:1904009	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
2.6	30.7	GO:0033504	floor plate development(GO:0033504)
2.6	10.2	GO:1904349	positive regulation of small intestine smooth muscle contraction(GO:1904349)
2.5	17.4	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
2.5	22.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
2.5	7.4	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
2.4	24.0	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
2.4	21.5	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
2.3	20.8	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
2.3	6.9	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
2.1	6.2	GO:1903632	positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
2.0	14.3	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
2.0	6.1	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
2.0	6.1	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
1.9	7.8	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
1.9	24.9	GO:0007000	nucleolus organization(GO:0007000)
1.8	11.1	GO:1903490	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
1.7	16.8	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
1.7	28.5	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
1.7	18.2	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
1.6	18.1	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
1.6	8.1	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
1.6	6.4	GO:0040030	nucleosome positioning(GO:0016584) regulation of molecular function, epigenetic(GO:0040030)
1.5	47.7	GO:0040034	regulation of development, heterochronic(GO:0040034)
1.5	6.0	GO:0060382	release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
1.5	5.9	GO:2000016	negative regulation of determination of dorsal identity(GO:2000016)
1.5	10.3	GO:0055096	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
1.5	4.4	GO:0034970	histone H3-R2 methylation(GO:0034970)
1.4	4.3	GO:0060936	transforming growth factor beta receptor complex assembly(GO:0007181) cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
1.3	13.4	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
1.3	48.1	GO:1902751	positive regulation of cell cycle G2/M phase transition(GO:1902751)
1.3	4.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
1.3	4.0	GO:0019389	glucuronoside metabolic process(GO:0019389)
1.3	45.0	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.2	12.4	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
1.2	18.4	GO:0001833	inner cell mass cell proliferation(GO:0001833)
1.1	3.4	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
1.1	4.3	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
1.0	20.8	GO:0009303	rRNA transcription(GO:0009303)
1.0	62.5	GO:0008156	negative regulation of DNA replication(GO:0008156)
1.0	3.0	GO:1902226	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
1.0	12.1	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
1.0	10.0	GO:1903715	regulation of aerobic respiration(GO:1903715)
1.0	6.8	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.9	7.5	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.9	5.4	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.9	2.6	GO:0000494	box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.8	2.5	GO:0043686	co-translational protein modification(GO:0043686)
0.8	34.8	GO:0006284	base-excision repair(GO:0006284)
0.8	2.3	GO:0042128	nitrate assimilation(GO:0042128)
0.8	3.0	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.7	16.2	GO:0043486	histone exchange(GO:0043486)
0.7	2.2	GO:1904092	regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.7	1.4	GO:0023035	CD40 signaling pathway(GO:0023035)
0.7	6.8	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.7	4.7	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.7	7.2	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.7	4.6	GO:0061010	gall bladder development(GO:0061010)
0.6	50.1	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.6	8.3	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.6	43.9	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.6	3.1	GO:0061622	glycolytic process through glucose-1-phosphate(GO:0061622)
0.6	2.5	GO:0001543	ovarian follicle rupture(GO:0001543)
0.6	4.7	GO:0051660	establishment of centrosome localization(GO:0051660)
0.6	1.8	GO:0006021	inositol biosynthetic process(GO:0006021)
0.6	10.3	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.6	9.1	GO:0043589	skin morphogenesis(GO:0043589)
0.6	7.8	GO:0080009	mRNA methylation(GO:0080009)
0.5	4.6	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.5	7.5	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.5	14.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.5	8.1	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.4	7.1	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.4	25.2	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.4	2.8	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
0.4	3.9	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.4	2.3	GO:0050758	thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.4	1.5	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.4	1.8	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.4	3.9	GO:1904251	regulation of bile acid metabolic process(GO:1904251)
0.4	1.1	GO:0071929	alpha-tubulin acetylation(GO:0071929)
0.4	2.8	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.3	4.1	GO:0060923	cardiac muscle cell fate commitment(GO:0060923)
0.3	43.2	GO:0035308	negative regulation of protein dephosphorylation(GO:0035308)
0.3	10.2	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response(GO:0002204) somatic diversification of immunoglobulins involved in immune response(GO:0002208) isotype switching(GO:0045190)
0.3	6.6	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.3	4.0	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.3	10.9	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.3	5.4	GO:1904816	regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.3	7.5	GO:0034453	microtubule anchoring(GO:0034453)
0.2	1.5	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.2	8.3	GO:0030033	microvillus assembly(GO:0030033)
0.2	4.0	GO:0042407	cristae formation(GO:0042407)
0.2	6.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.2	0.9	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.2	11.2	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2	6.1	GO:0007099	centriole replication(GO:0007099)
0.2	0.5	GO:0036090	cleavage furrow ingression(GO:0036090)
0.2	3.3	GO:0072422	signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.2	1.2	GO:0021636	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2	2.2	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.1	1.2	GO:0031055	chromatin remodeling at centromere(GO:0031055) pericentric heterochromatin assembly(GO:0031508)
0.1	5.9	GO:0016925	protein sumoylation(GO:0016925)
0.1	0.9	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	12.0	GO:0051225	spindle assembly(GO:0051225)
0.1	2.4	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.6	GO:0003349	epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.1	10.2	GO:0016579	protein deubiquitination(GO:0016579)
0.1	1.8	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.1	1.0	GO:0097368	histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.1	5.6	GO:0007569	cell aging(GO:0007569)
0.1	1.3	GO:0060056	mammary gland involution(GO:0060056)
0.1	0.6	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.1	5.0	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
0.1	4.0	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	7.8	GO:0051028	mRNA transport(GO:0051028)
0.1	2.5	GO:0060416	response to growth hormone(GO:0060416)
0.1	5.6	GO:0043966	histone H3 acetylation(GO:0043966)
0.1	0.4	GO:0060356	leucine import(GO:0060356)
0.1	3.3	GO:0038066	p38MAPK cascade(GO:0038066)
0.1	2.1	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.1	0.5	GO:0036337	Fas signaling pathway(GO:0036337)
0.1	19.5	GO:0007018	microtubule-based movement(GO:0007018)
0.1	4.1	GO:0001541	ovarian follicle development(GO:0001541)
0.1	1.1	GO:0035066	positive regulation of histone acetylation(GO:0035066)
0.1	16.0	GO:0048511	rhythmic process(GO:0048511)
0.0	2.0	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	3.1	GO:0048635	negative regulation of muscle organ development(GO:0048635)
0.0	5.9	GO:0030010	establishment of cell polarity(GO:0030010)
0.0	0.6	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.2	GO:0042737	drug catabolic process(GO:0042737)
0.0	3.6	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.0	5.3	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	2.0	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	2.5	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	2.1	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0	2.2	GO:0006364	rRNA processing(GO:0006364)
0.0	29.8	GO:0006915	apoptotic process(GO:0006915)
0.0	2.1	GO:0051090	regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
47.0	281.7	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
30.7	491.5	GO:0042555	MCM complex(GO:0042555)
15.0	75.1	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
12.9	38.8	GO:0000811	GINS complex(GO:0000811)
12.4	62.0	GO:0035189	Rb-E2F complex(GO:0035189)
10.6	53.2	GO:0031298	replication fork protection complex(GO:0031298)
7.5	59.9	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
6.0	18.0	GO:0070557	PCNA-p21 complex(GO:0070557)
5.4	43.5	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
5.1	35.9	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
4.7	28.3	GO:0033553	rDNA heterochromatin(GO:0033553)
4.4	4.4	GO:0035061	interchromatin granule(GO:0035061)
4.3	38.3	GO:0016012	sarcoglycan complex(GO:0016012)
3.3	26.5	GO:0001651	dense fibrillar component(GO:0001651)
3.2	208.1	GO:0005657	replication fork(GO:0005657)
3.0	9.1	GO:0005584	collagen type I trimer(GO:0005584)
3.0	12.1	GO:0008275	gamma-tubulin small complex(GO:0008275)
2.9	14.7	GO:0032389	MutLalpha complex(GO:0032389)
2.8	25.4	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
2.8	41.5	GO:0000243	commitment complex(GO:0000243)
2.5	17.8	GO:0097443	sorting endosome(GO:0097443)
2.5	10.1	GO:0001740	Barr body(GO:0001740)
2.4	28.7	GO:0000796	condensin complex(GO:0000796)
2.4	14.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
1.9	11.7	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
1.5	10.6	GO:0005638	lamin filament(GO:0005638)
1.5	20.8	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
1.4	4.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
1.4	8.7	GO:0044530	supraspliceosomal complex(GO:0044530)
1.4	12.8	GO:0070652	HAUS complex(GO:0070652)
1.4	7.1	GO:0031251	PAN complex(GO:0031251)
1.3	74.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.3	15.6	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.3	264.1	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
1.3	24.2	GO:0005686	U2 snRNP(GO:0005686)
1.1	32.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
1.1	12.4	GO:0000801	central element(GO:0000801)
1.1	7.8	GO:0036396	MIS complex(GO:0036396)
1.0	15.7	GO:0001673	male germ cell nucleus(GO:0001673)
1.0	11.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.9	31.5	GO:0035861	site of double-strand break(GO:0035861)
0.9	6.1	GO:0098536	deuterosome(GO:0098536)
0.8	3.0	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.7	4.6	GO:0034709	methylosome(GO:0034709)
0.6	3.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.6	30.1	GO:0051233	spindle midzone(GO:0051233)
0.6	11.6	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.6	4.3	GO:0044611	nuclear pore inner ring(GO:0044611)
0.6	3.0	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.6	22.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.6	58.9	GO:0005776	autophagosome(GO:0005776)
0.6	7.8	GO:0031080	nuclear pore outer ring(GO:0031080)
0.6	6.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.5	20.8	GO:0005719	nuclear euchromatin(GO:0005719)
0.5	7.8	GO:0044232	organelle membrane contact site(GO:0044232)
0.5	4.0	GO:0061617	MICOS complex(GO:0061617)
0.5	5.4	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.5	7.4	GO:0000791	euchromatin(GO:0000791)
0.5	7.8	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.4	10.3	GO:0042627	chylomicron(GO:0042627)
0.4	24.9	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.4	6.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4	30.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.4	2.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.4	40.1	GO:0016363	nuclear matrix(GO:0016363)
0.3	2.4	GO:0000124	SAGA complex(GO:0000124)
0.3	25.3	GO:0005871	kinesin complex(GO:0005871)
0.3	1.0	GO:0070876	SOSS complex(GO:0070876)
0.3	6.5	GO:1904115	axon cytoplasm(GO:1904115)
0.3	3.6	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.3	3.7	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3	2.3	GO:1990761	growth cone lamellipodium(GO:1990761)
0.3	24.8	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.2	34.2	GO:0005681	spliceosomal complex(GO:0005681)
0.2	4.5	GO:0070822	Sin3-type complex(GO:0070822)
0.2	1.8	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.2	1.5	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	9.6	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	33.1	GO:0005819	spindle(GO:0005819)
0.1	1.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	1.6	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	9.9	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.1	8.3	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.1	2.0	GO:0005605	basal lamina(GO:0005605)
0.1	29.2	GO:0005874	microtubule(GO:0005874)
0.1	1.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.1	3.7	GO:0045171	intercellular bridge(GO:0045171)
0.1	6.6	GO:0000502	proteasome complex(GO:0000502)
0.1	26.2	GO:0005667	transcription factor complex(GO:0005667)
0.1	4.0	GO:0005643	nuclear pore(GO:0005643)
0.1	0.6	GO:0016589	NURF complex(GO:0016589)
0.1	5.3	GO:0016459	myosin complex(GO:0016459)
0.0	5.2	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	2.1	GO:0030686	90S preribosome(GO:0030686)
0.0	20.9	GO:0005813	centrosome(GO:0005813)
0.0	5.8	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	8.3	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.4	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	9.7	GO:0043292	contractile fiber(GO:0043292)
0.0	0.5	GO:0070938	contractile ring(GO:0070938)
0.0	144.4	GO:0005829	cytosol(GO:0005829)
0.0	4.5	GO:0000790	nuclear chromatin(GO:0000790)
0.0	43.7	GO:0005887	integral component of plasma membrane(GO:0005887)
0.0	0.5	GO:0016605	PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
47.0	281.7	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
15.9	111.6	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
10.0	179.6	GO:0003688	DNA replication origin binding(GO:0003688)
9.7	38.8	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
8.4	50.2	GO:0010997	anaphase-promoting complex binding(GO:0010997)
7.4	29.6	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
6.9	20.8	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
6.6	46.3	GO:0044547	DNA topoisomerase binding(GO:0044547)
6.3	265.9	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
6.3	12.7	GO:0000405	bubble DNA binding(GO:0000405)
6.0	18.0	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
5.8	17.5	GO:0030350	iron-responsive element binding(GO:0030350)
5.6	50.2	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
4.6	41.5	GO:0000150	recombinase activity(GO:0000150)
4.4	30.5	GO:0048256	flap endonuclease activity(GO:0048256)
4.3	21.5	GO:0071987	WD40-repeat domain binding(GO:0071987)
3.9	122.2	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
3.9	27.4	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
3.8	46.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
3.7	77.5	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
3.7	124.9	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
3.5	28.3	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
3.3	59.9	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
3.3	9.9	GO:0004798	thymidylate kinase activity(GO:0004798)
3.2	41.5	GO:1990446	U1 snRNP binding(GO:1990446)
2.7	21.4	GO:0061676	importin-alpha family protein binding(GO:0061676)
2.5	7.4	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.5	9.8	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
2.4	19.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
2.4	9.5	GO:0036033	mediator complex binding(GO:0036033)
2.1	8.3	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
1.9	18.6	GO:0032404	mismatch repair complex binding(GO:0032404)
1.8	9.1	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
1.7	6.9	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
1.7	30.2	GO:1990226	histone methyltransferase binding(GO:1990226)
1.6	14.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
1.5	17.6	GO:0043024	ribosomal small subunit binding(GO:0043024)
1.4	11.1	GO:0051425	PTB domain binding(GO:0051425)
1.4	6.8	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
1.3	10.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
1.1	8.0	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
1.1	14.3	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
1.0	3.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.9	62.5	GO:0070491	repressing transcription factor binding(GO:0070491)
0.9	2.6	GO:0036009	protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.8	277.1	GO:0001047	core promoter binding(GO:0001047)
0.8	11.3	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.8	8.8	GO:0001055	RNA polymerase II activity(GO:0001055)
0.8	26.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.7	13.9	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.7	3.9	GO:0004594	pantothenate kinase activity(GO:0004594)
0.7	2.0	GO:0070698	type I activin receptor binding(GO:0070698)
0.6	3.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.6	12.4	GO:0070182	DNA polymerase binding(GO:0070182)
0.6	12.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.6	1.8	GO:0004512	inositol-3-phosphate synthase activity(GO:0004512) intramolecular lyase activity(GO:0016872)
0.6	7.5	GO:0046790	virion binding(GO:0046790)
0.6	9.0	GO:0031386	protein tag(GO:0031386)
0.5	9.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.5	8.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.5	10.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.5	2.3	GO:0098809	nitrite reductase activity(GO:0098809)
0.5	6.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.5	1.8	GO:0051525	NFAT protein binding(GO:0051525)
0.5	60.6	GO:0004386	helicase activity(GO:0004386)
0.4	4.4	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.4	4.3	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.4	80.9	GO:0042393	histone binding(GO:0042393)
0.4	2.3	GO:0050816	phosphothreonine binding(GO:0050816)
0.4	32.9	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3	9.6	GO:0043274	phospholipase binding(GO:0043274)
0.3	5.1	GO:0031996	thioesterase binding(GO:0031996)
0.3	4.0	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.3	8.3	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.3	4.6	GO:0008327	methyl-CpG binding(GO:0008327)
0.3	7.7	GO:0004407	histone deacetylase activity(GO:0004407)
0.3	7.1	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.3	0.9	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3	6.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.3	37.6	GO:0051087	chaperone binding(GO:0051087)
0.3	38.8	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.3	22.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3	2.5	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2	6.5	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.2	2.2	GO:0034511	U3 snoRNA binding(GO:0034511)
0.2	64.9	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2	5.3	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2	2.2	GO:0070888	E-box binding(GO:0070888)
0.2	25.3	GO:0003777	microtubule motor activity(GO:0003777)
0.2	1.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.2	2.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.2	26.4	GO:0031072	heat shock protein binding(GO:0031072)
0.2	7.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.2	7.5	GO:0036002	pre-mRNA binding(GO:0036002)
0.2	5.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.2	74.7	GO:0005096	GTPase activator activity(GO:0005096)
0.2	1.8	GO:0015288	porin activity(GO:0015288)
0.2	12.4	GO:0048365	Rac GTPase binding(GO:0048365)
0.2	1.0	GO:0003680	AT DNA binding(GO:0003680)
0.1	3.4	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	17.2	GO:0004519	endonuclease activity(GO:0004519)
0.1	5.4	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	4.7	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	6.0	GO:0031369	translation initiation factor binding(GO:0031369)
0.1	0.9	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1	1.4	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.1	6.7	GO:0016779	nucleotidyltransferase activity(GO:0016779)
0.1	27.5	GO:0015631	tubulin binding(GO:0015631)
0.1	11.6	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1	0.5	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	3.3	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	2.4	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	2.5	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	6.5	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.6	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	21.9	GO:0046982	protein heterodimerization activity(GO:0046982)
0.0	4.0	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0	3.0	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	15.3	GO:0008270	zinc ion binding(GO:0008270)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	3.5	GO:0008134	transcription factor binding(GO:0008134)
0.0	0.4	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	1.5	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.5	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0	0.7	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.5	154.9	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
11.3	203.8	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
8.3	414.3	PID ATR PATHWAY	ATR signaling pathway
4.5	460.2	PID E2F PATHWAY	E2F transcription factor network
2.4	30.9	PID MYC PATHWAY	C-MYC pathway
2.2	34.8	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
1.3	165.6	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
1.0	29.6	PID BARD1 PATHWAY	BARD1 signaling events
1.0	76.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.9	54.7	PID PLK1 PATHWAY	PLK1 signaling events
0.8	30.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.5	55.1	PID CMYB PATHWAY	C-MYB transcription factor network
0.3	7.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3	24.9	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.3	10.3	PID AURORA B PATHWAY	Aurora B signaling
0.3	4.9	PID ATM PATHWAY	ATM pathway
0.3	17.8	SIG CHEMOTAXIS	Genes related to chemotaxis
0.3	17.5	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.2	16.0	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.2	3.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.2	3.0	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	10.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.2	8.7	PID P53 REGULATION PATHWAY	p53 pathway
0.2	15.6	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.2	4.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	9.9	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	10.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	2.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.1	5.1	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	0.5	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	5.3	PID NOTCH PATHWAY	Notch signaling pathway
0.0	2.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	2.0	PID BMP PATHWAY	BMP receptor signaling
0.0	1.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
34.1	546.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
24.7	544.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
16.0	224.6	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
10.1	20.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
7.9	133.8	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
4.3	42.7	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
2.8	42.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
2.6	115.0	REACTOME G1 PHASE	Genes involved in G1 Phase
2.3	37.0	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
1.5	12.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
1.4	6.9	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
1.2	29.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
1.0	49.4	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
1.0	43.5	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
1.0	11.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.9	27.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.8	25.3	REACTOME KINESINS	Genes involved in Kinesins
0.7	17.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.6	11.6	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.6	5.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.6	23.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.6	69.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.6	9.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.6	19.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.5	8.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.5	9.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.4	5.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4	22.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.4	12.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	6.8	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.3	10.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.3	69.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.3	3.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	3.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.2	25.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.2	8.6	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.2	6.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.2	24.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.8	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	2.0	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	1.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	3.1	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	7.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	1.0	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	3.6	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1	2.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	3.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	2.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	1.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import