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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for E2f4

Z-value: 6.44

Motif logo

Transcription factors associated with E2f4

Gene Symbol Gene ID Gene Info
ENSMUSG00000014859.10 E2f4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f4mm39_v1_chr8_+_106024294_1060243670.972.0e-22Click!

Activity profile of E2f4 motif

Sorted Z-values of E2f4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_37806912 41.79 ENSMUST00000108023.10
cyclin E1
chr6_+_124807176 40.50 ENSMUST00000131847.8
ENSMUST00000151674.3
cell division cycle associated 3
chr11_+_68936457 39.39 ENSMUST00000108666.8
ENSMUST00000021277.6
aurora kinase B
chr16_-_30129591 36.01 ENSMUST00000061190.8
glycoprotein 5 (platelet)
chr4_+_134238310 35.21 ENSMUST00000105866.3
aurora kinase A and ninein interacting protein
chr15_+_79776597 33.91 ENSMUST00000175714.8
ENSMUST00000109620.10
ENSMUST00000165537.8
ENSMUST00000175752.8
ENSMUST00000176325.8
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr4_-_133694607 32.30 ENSMUST00000105893.8
high mobility group nucleosomal binding domain 2
chr19_+_6135013 30.70 ENSMUST00000025704.3
cell division cycle associated 5
chr18_-_34884555 30.62 ENSMUST00000060710.9
cell division cycle 25C
chr12_+_24758240 29.84 ENSMUST00000020980.12
ribonucleotide reductase M2
chr2_+_162896602 28.83 ENSMUST00000018005.10
myeloblastosis oncogene-like 2
chr4_-_133694543 28.75 ENSMUST00000123234.8
high mobility group nucleosomal binding domain 2
chr11_+_74510413 28.68 ENSMUST00000100866.3
coiled-coil domain containing 92B
chr9_+_72345801 28.64 ENSMUST00000184604.8
ENSMUST00000034746.10
meiosis-specific nuclear structural protein 1
chr1_-_169358912 25.22 ENSMUST00000192248.2
ENSMUST00000028000.13
NUF2, NDC80 kinetochore complex component
chr9_+_44245981 24.72 ENSMUST00000052686.4
H2A.X variant histone
chr8_-_54091980 24.35 ENSMUST00000047768.11
nei like 3 (E. coli)
chrX_+_8137372 24.18 ENSMUST00000127103.8
ENSMUST00000115591.8
solute carrier family 38, member 5
chr14_-_87378641 23.51 ENSMUST00000168889.3
ENSMUST00000022599.14
diaphanous related formin 3
chr4_-_132072988 22.38 ENSMUST00000030726.13
regulator of chromosome condensation 1
chr4_-_133695204 22.20 ENSMUST00000100472.10
ENSMUST00000136327.2
high mobility group nucleosomal binding domain 2
chr17_-_25946370 22.08 ENSMUST00000170070.3
ENSMUST00000048054.14
CTF18, chromosome transmission fidelity factor 18
chrX_+_8137620 21.72 ENSMUST00000033512.11
solute carrier family 38, member 5
chr4_-_132073048 21.65 ENSMUST00000084250.11
regulator of chromosome condensation 1
chr9_+_72345267 21.49 ENSMUST00000183809.8
meiosis-specific nuclear structural protein 1
chr1_-_33708876 20.82 ENSMUST00000027312.11
DNA primase, p58 subunit
chrX_+_8137881 20.17 ENSMUST00000115590.2
solute carrier family 38, member 5
chr1_-_169359015 19.89 ENSMUST00000111368.8
NUF2, NDC80 kinetochore complex component
chr4_-_115980813 19.55 ENSMUST00000102704.4
ENSMUST00000102705.10
RAD54 like (S. cerevisiae)
chr6_+_113508636 18.61 ENSMUST00000036340.12
ENSMUST00000204827.3
Fanconi anemia, complementation group D2
chr18_+_56840813 18.23 ENSMUST00000025486.9
lamin B1
chr9_+_107828136 17.34 ENSMUST00000049348.9
ENSMUST00000194271.2
TRAF-interacting protein
chr4_-_133695264 17.10 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chrX_+_141464393 16.26 ENSMUST00000112889.8
ENSMUST00000101198.9
ENSMUST00000112891.8
ENSMUST00000087333.9
transmembrane protein 164
chr5_+_123214332 15.92 ENSMUST00000067505.15
ENSMUST00000111619.10
ENSMUST00000160344.2
transmembrane protein 120B
chr15_-_76524097 15.28 ENSMUST00000168185.8
tonsoku-like, DNA repair protein
chr13_-_74085880 15.27 ENSMUST00000022053.11
thyroid hormone receptor interactor 13
chr18_-_60981981 14.90 ENSMUST00000177172.8
ENSMUST00000175934.8
ENSMUST00000176630.8
treacle ribosome biogenesis factor 1
chr5_-_138170644 14.67 ENSMUST00000000505.16
minichromosome maintenance complex component 7
chr10_-_87982732 14.39 ENSMUST00000164121.8
ENSMUST00000164803.2
ENSMUST00000168163.8
ENSMUST00000048518.16
PARP1 binding protein
chr8_+_18645144 14.05 ENSMUST00000039412.15
microcephaly, primary autosomal recessive 1
chr16_-_90524214 13.58 ENSMUST00000099554.5
MIS18 kinetochore protein A
chr11_-_101442663 13.39 ENSMUST00000017290.11
breast cancer 1, early onset
chr1_-_189420270 13.37 ENSMUST00000171929.8
ENSMUST00000165962.2
centromere protein F
chr15_+_12824925 13.02 ENSMUST00000090292.13
drosha, ribonuclease type III
chr12_+_105976463 12.81 ENSMUST00000072040.7
vaccinia related kinase 1
chr15_+_12824901 12.76 ENSMUST00000169061.8
drosha, ribonuclease type III
chr12_+_105976533 12.72 ENSMUST00000085026.12
ENSMUST00000021539.16
vaccinia related kinase 1
chr2_+_129435448 12.62 ENSMUST00000049262.14
ENSMUST00000163034.8
ENSMUST00000160276.2
signal-regulatory protein alpha
chrX_-_165992145 12.61 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr3_-_54823287 12.56 ENSMUST00000070342.4
serine rich and transmembrane domain containing 1
chr5_-_138170077 12.45 ENSMUST00000155902.8
ENSMUST00000148879.8
minichromosome maintenance complex component 7
chr6_-_56681657 12.05 ENSMUST00000176595.3
ENSMUST00000170382.5
ENSMUST00000203958.2
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr4_-_59783780 11.76 ENSMUST00000107526.8
ENSMUST00000095063.11
INTS3 and NABP interacting protein
chr12_+_117807607 11.71 ENSMUST00000176735.8
ENSMUST00000177339.2
cell division cycle associated 7 like
chr7_+_126808016 11.20 ENSMUST00000206204.2
ENSMUST00000206772.2
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_+_180961507 11.04 ENSMUST00000098971.11
ENSMUST00000054622.15
ENSMUST00000108814.8
ENSMUST00000048608.16
ENSMUST00000108815.8
regulator of telomere elongation helicase 1
chr9_+_44045859 10.97 ENSMUST00000034650.15
ENSMUST00000098852.3
ENSMUST00000216002.2
melanoma cell adhesion molecule
chr5_-_33809640 10.79 ENSMUST00000151081.2
ENSMUST00000139518.8
ENSMUST00000101354.10
stem-loop binding protein
chr5_-_33809872 10.71 ENSMUST00000057551.14
stem-loop binding protein
chr2_+_30176395 10.24 ENSMUST00000064447.12
nucleoporin 188
chr13_+_23719579 9.94 ENSMUST00000080859.8
H3 clustered histone 8
chr17_+_35219941 9.87 ENSMUST00000087315.14
valyl-tRNA synthetase
chrX_+_104123341 9.59 ENSMUST00000033577.11
polysaccharide biosynthesis domain containing 1
chr3_-_10273628 9.46 ENSMUST00000029041.6
fatty acid binding protein 4, adipocyte
chr17_+_35219998 9.35 ENSMUST00000173584.8
valyl-tRNA synthetase
chr2_+_129435115 9.34 ENSMUST00000099113.10
ENSMUST00000103202.10
signal-regulatory protein alpha
chr9_+_57615816 9.31 ENSMUST00000043990.14
ENSMUST00000142807.2
enhancer of mRNA decapping 3
chr1_+_9868332 9.21 ENSMUST00000166384.8
ENSMUST00000168907.8
serum/glucocorticoid regulated kinase 3
chr5_-_33809683 9.13 ENSMUST00000075670.13
stem-loop binding protein
chr2_-_3513783 9.09 ENSMUST00000124331.8
ENSMUST00000140494.2
ENSMUST00000027961.12
predicted gene 45902
heat shock protein 14
chr12_+_99850756 9.01 ENSMUST00000153627.8
tyrosyl-DNA phosphodiesterase 1
chr8_+_108271643 8.94 ENSMUST00000212543.2
WW domain containing E3 ubiquitin protein ligase 2
chrX_+_161684563 8.82 ENSMUST00000112303.8
ENSMUST00000033727.14
cytidine 5'-triphosphate synthase 2
chr19_+_46064409 8.54 ENSMUST00000223728.2
ENSMUST00000235620.2
nucleolar and coiled-body phosphoprotein 1
chrX_+_161684221 8.44 ENSMUST00000101095.9
cytidine 5'-triphosphate synthase 2
chr6_+_70703409 8.41 ENSMUST00000103410.3
immunoglobulin kappa constant
chr14_+_76725876 8.36 ENSMUST00000101618.9
TSC22 domain family, member 1
chr17_+_35220252 8.33 ENSMUST00000174260.8
valyl-tRNA synthetase
chr14_-_54754810 8.11 ENSMUST00000023873.12
protein arginine N-methyltransferase 5
chr13_-_23929490 8.03 ENSMUST00000091752.5
H3 clustered histone 3
chr9_+_108820846 8.01 ENSMUST00000198140.5
ENSMUST00000051873.15
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr9_-_32255604 7.88 ENSMUST00000034533.7
potassium inwardly-rectifying channel, subfamily J, member 5
chr2_+_24257576 7.69 ENSMUST00000140547.2
ENSMUST00000102942.8
pleckstrin and Sec7 domain containing 4
chr4_-_3835595 7.54 ENSMUST00000138502.2
ribosomal protein S20
chr4_+_11558905 7.54 ENSMUST00000095145.12
ENSMUST00000108306.9
ENSMUST00000070755.13
RAD54 homolog B (S. cerevisiae)
chr15_-_98729333 7.20 ENSMUST00000168846.3
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr5_-_113910571 7.12 ENSMUST00000019118.8
squamous cell carcinoma antigen recognized by T cells 3
chr7_-_126807581 7.10 ENSMUST00000120705.3
TBC1 domain family, member 10b
chr5_+_31046196 6.85 ENSMUST00000069705.11
ENSMUST00000201917.4
ENSMUST00000201168.4
ENSMUST00000202060.4
ENSMUST00000201225.4
ENSMUST00000114700.9
ATP/GTP binding protein-like 5
chr6_-_36787096 6.78 ENSMUST00000201321.2
ENSMUST00000101534.5
pleiotrophin
chr7_+_24920840 6.59 ENSMUST00000055604.6
zinc finger protein 526
chr9_-_32255556 6.57 ENSMUST00000214223.2
potassium inwardly-rectifying channel, subfamily J, member 5
chr4_-_43562397 6.53 ENSMUST00000030187.14
talin 1
chr5_-_25910788 6.39 ENSMUST00000030773.12
X-ray repair complementing defective repair in Chinese hamster cells 2
chrX_+_161684735 6.38 ENSMUST00000112302.8
ENSMUST00000112301.8
cytidine 5'-triphosphate synthase 2
chr11_-_106890307 6.24 ENSMUST00000018506.13
karyopherin (importin) alpha 2
chr9_-_32255533 6.17 ENSMUST00000216033.2
potassium inwardly-rectifying channel, subfamily J, member 5
chr17_+_35201074 6.00 ENSMUST00000007266.14
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr8_+_124750133 5.97 ENSMUST00000034457.9
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr3_-_142587419 5.96 ENSMUST00000174422.8
ENSMUST00000173830.8
protein kinase N2
chr19_-_5416626 5.83 ENSMUST00000237167.2
BAF nuclear assembly factor 1
chr2_+_129434834 5.76 ENSMUST00000103203.8
signal-regulatory protein alpha
chr8_+_18645543 5.71 ENSMUST00000146819.8
microcephaly, primary autosomal recessive 1
chr8_-_106223502 5.47 ENSMUST00000212303.2
zinc finger, DHHC domain containing 1
chr7_+_24584076 5.38 ENSMUST00000153451.9
ENSMUST00000108429.8
ribosomal protein S19
chr13_+_74085916 5.32 ENSMUST00000222399.2
ENSMUST00000099384.4
bromodomain containing 9
chr4_+_44004437 5.27 ENSMUST00000107846.10
clathrin, light polypeptide (Lca)
chr7_+_97020810 5.25 ENSMUST00000098300.6
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
chr11_-_106890195 5.18 ENSMUST00000106768.2
ENSMUST00000144834.8
karyopherin (importin) alpha 2
chr19_+_6451667 5.12 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr7_-_92523396 5.06 ENSMUST00000209074.2
ENSMUST00000208356.2
ENSMUST00000032877.11
DNA damage-induced apoptosis suppressor
chrX_+_163763588 4.81 ENSMUST00000167446.8
ENSMUST00000057150.8
Fanconi anemia, complementation group B
chr10_+_87982854 4.73 ENSMUST00000052355.15
nucleoporin 37
chr10_+_12936248 4.59 ENSMUST00000193426.6
pleiomorphic adenoma gene-like 1
chr10_+_36850532 4.58 ENSMUST00000019911.14
ENSMUST00000105510.2
histone deacetylase 2
chr9_+_106354463 4.47 ENSMUST00000047721.10
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
chr1_+_52669849 4.43 ENSMUST00000165859.8
nuclear envelope integral membrane protein 2
chr14_+_55815580 4.31 ENSMUST00000174484.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr17_+_35201130 4.30 ENSMUST00000173004.2
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr2_+_30176418 4.28 ENSMUST00000138666.8
ENSMUST00000113634.3
nucleoporin 188
chr10_+_87982916 4.00 ENSMUST00000169309.3
nucleoporin 37
chr12_-_4283926 3.94 ENSMUST00000111169.10
ENSMUST00000020981.12
centromere protein O
chr1_+_85822250 3.82 ENSMUST00000185569.2
integral membrane protein 2C
chr9_-_123507847 3.79 ENSMUST00000170591.2
ENSMUST00000171647.9
solute carrier family 6 (neurotransmitter transporter), member 20A
chr19_+_46064302 3.76 ENSMUST00000165017.2
ENSMUST00000223741.2
ENSMUST00000225780.2
nucleolar and coiled-body phosphoprotein 1
chr17_+_25946644 3.44 ENSMUST00000237183.2
ENSMUST00000237785.2
ENSMUST00000047273.3
RNA pseudouridylate synthase domain containing 1
chr17_-_57338468 3.39 ENSMUST00000007814.10
ENSMUST00000233480.2
KH-type splicing regulatory protein
chr1_-_10108325 3.35 ENSMUST00000027050.10
ENSMUST00000188619.2
COP9 signalosome subunit 5
chr5_-_92496730 3.35 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr2_+_180961599 3.07 ENSMUST00000153112.2
regulator of telomere elongation helicase 1
chr2_+_71617266 3.06 ENSMUST00000112101.8
ENSMUST00000028522.10
integrin alpha 6
chr15_+_55171138 2.64 ENSMUST00000023053.12
ENSMUST00000110217.10
collagen, type XIV, alpha 1
chr17_-_87332780 2.62 ENSMUST00000024957.7
phosphatidylinositol glycan anchor biosynthesis, class F
chr1_+_92862432 2.16 ENSMUST00000117814.8
calpain 10
chr11_-_6556053 2.15 ENSMUST00000045713.4
NAC alpha domain containing
chrX_+_104123367 2.14 ENSMUST00000119477.2
polysaccharide biosynthesis domain containing 1
chr5_+_21577640 2.07 ENSMUST00000035799.6
fibrinogen-like protein 2
chr2_+_106525938 1.96 ENSMUST00000016530.14
metallophosphoesterase domain containing 2
chr1_-_179631190 1.75 ENSMUST00000027768.14
AT hook containing transcription factor 1
chr19_+_8713156 1.68 ENSMUST00000210512.2
ENSMUST00000049424.11
WD repeat domain 74
chr4_-_141553306 1.56 ENSMUST00000102481.4
chymotrypsin-like elastase family, member 2A
chr2_-_145776934 1.52 ENSMUST00000001818.5
crooked neck pre-mRNA splicing factor 1
chrX_+_12454031 1.50 ENSMUST00000033313.3
ATPase, H+ transporting, lysosomal accessory protein 2
chr1_-_74640504 1.46 ENSMUST00000136078.2
ENSMUST00000132081.2
ENSMUST00000113721.8
ENSMUST00000027357.12
ring finger protein 25
chr2_+_125994050 1.26 ENSMUST00000170908.8
DTW domain containing 1
chr17_-_84495364 1.17 ENSMUST00000060366.7
zinc finger protein 36, C3H type-like 2
chr2_+_112114906 1.16 ENSMUST00000053666.8
solute carrier family 12, member 6
chr15_+_57775595 1.12 ENSMUST00000022992.13
TBC1 domain family, member 31
chr13_+_74086241 0.97 ENSMUST00000222749.2
bromodomain containing 9
chr3_-_116456292 0.96 ENSMUST00000029570.9
major facilitator superfamily domain containing 14A
chr5_+_31046670 0.92 ENSMUST00000200850.2
ATP/GTP binding protein-like 5
chr9_-_82857528 0.88 ENSMUST00000034787.12
pleckstrin homology domain interacting protein
chr14_+_30741082 0.86 ENSMUST00000112098.11
ENSMUST00000112095.8
ENSMUST00000112106.8
ENSMUST00000146325.8
polybromo 1
chr7_-_16019379 0.78 ENSMUST00000174270.8
coiled-coil domain containing 9
chr1_-_77491683 0.75 ENSMUST00000186930.2
ENSMUST00000027451.13
ENSMUST00000188797.7
Eph receptor A4
chr17_+_87332978 0.42 ENSMUST00000024959.10
cysteine-rich PDZ-binding protein
chr12_-_118162652 0.25 ENSMUST00000084806.7
dynein, axonemal, heavy chain 11
chr17_+_35200823 0.19 ENSMUST00000114011.11
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr7_-_126859790 0.10 ENSMUST00000035276.5
dCTP pyrophosphatase 1
chr10_+_17598961 0.09 ENSMUST00000038107.9
ENSMUST00000219558.2
ENSMUST00000218370.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr19_+_5416769 0.08 ENSMUST00000025759.9
eukaryotic translation initiation factor 1A domain containing
chr3_-_142587678 0.05 ENSMUST00000043812.15
protein kinase N2
chr6_-_24956296 0.05 ENSMUST00000127247.4
transmembrane protein 229A
chr17_+_31515163 0.01 ENSMUST00000235972.2
ENSMUST00000165149.3
ENSMUST00000236251.2
solute carrier family 37 (glycerol-3-phosphate transporter), member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
13.1 39.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
6.4 25.5 GO:0072355 histone H3-T3 phosphorylation(GO:0072355)
6.1 30.7 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
5.2 20.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
4.6 27.6 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
4.6 18.2 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
3.9 69.9 GO:0015816 glycine transport(GO:0015816)
3.5 14.1 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
3.2 25.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
3.1 99.9 GO:0040034 regulation of development, heterochronic(GO:0040034)
2.8 19.8 GO:0060623 regulation of chromosome condensation(GO:0060623)
2.8 50.2 GO:0070986 left/right axis specification(GO:0070986)
2.8 30.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
2.7 8.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
2.7 13.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
2.5 22.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
2.3 13.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
2.3 27.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
2.3 6.8 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) positive regulation of neuromuscular junction development(GO:1904398)
2.1 14.5 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
2.1 20.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
1.9 19.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.9 18.6 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.8 73.9 GO:0051290 protein heterotetramerization(GO:0051290)
1.7 15.3 GO:0007144 female meiosis I(GO:0007144)
1.6 33.9 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
1.6 23.6 GO:0006241 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
1.4 17.7 GO:0007000 nucleolus organization(GO:0007000)
1.4 14.9 GO:0014029 neural crest formation(GO:0014029)
1.4 17.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
1.3 36.0 GO:0010544 negative regulation of platelet activation(GO:0010544)
1.2 41.8 GO:0006270 DNA replication initiation(GO:0006270)
1.2 5.8 GO:0015074 DNA integration(GO:0015074)
1.2 17.3 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
1.0 27.1 GO:0008340 determination of adult lifespan(GO:0008340)
1.0 9.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.9 41.4 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.9 4.6 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.8 3.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.8 30.6 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.8 8.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.8 12.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.8 7.8 GO:0035608 protein deglutamylation(GO:0035608)
0.7 9.0 GO:0000012 single strand break repair(GO:0000012)
0.5 9.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.5 24.4 GO:0006284 base-excision repair(GO:0006284)
0.5 3.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.5 11.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.5 6.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.5 5.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.4 13.5 GO:0031297 replication fork processing(GO:0031297)
0.4 28.8 GO:0090307 mitotic spindle assembly(GO:0090307)
0.4 13.4 GO:0051310 metaphase plate congression(GO:0051310)
0.4 2.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3 3.4 GO:0031118 rRNA pseudouridine synthesis(GO:0031118) tRNA pseudouridine synthesis(GO:0031119)
0.3 27.7 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.3 3.4 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.3 3.9 GO:0034508 centromere complex assembly(GO:0034508)
0.3 1.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.3 35.2 GO:0007051 spindle organization(GO:0007051)
0.3 1.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.3 4.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.3 5.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.2 0.7 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 6.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 1.5 GO:0048069 eye pigmentation(GO:0048069)
0.2 7.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 2.2 GO:0035878 nail development(GO:0035878)
0.2 0.9 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.2 9.2 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 5.5 GO:0018345 protein palmitoylation(GO:0018345)
0.1 5.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.7 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 7.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 4.3 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.1 11.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 11.2 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.1 0.9 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 7.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 11.8 GO:0010212 response to ionizing radiation(GO:0010212)
0.1 0.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 8.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.6 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 2.6 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.1 9.3 GO:0051291 protein heterooligomerization(GO:0051291)
0.1 41.5 GO:0051301 cell division(GO:0051301)
0.1 5.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 2.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0042262 DNA protection(GO:0042262)
0.0 0.3 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 5.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 1.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 17.1 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 1.5 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 11.4 GO:0030036 actin cytoskeleton organization(GO:0030036)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.8 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
7.5 45.1 GO:0031262 Ndc80 complex(GO:0031262)
6.6 39.4 GO:0032133 chromosome passenger complex(GO:0032133)
5.0 29.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
4.8 28.8 GO:0031523 Myb complex(GO:0031523)
3.8 30.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
3.4 13.5 GO:0035101 FACT complex(GO:0035101)
3.0 20.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
2.6 18.2 GO:0005638 lamin filament(GO:0005638)
2.6 30.7 GO:0008278 cohesin complex(GO:0008278)
2.5 22.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
2.4 7.1 GO:0071001 U4/U6 snRNP(GO:0071001)
2.2 22.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
2.1 27.1 GO:0042555 MCM complex(GO:0042555)
2.1 14.5 GO:0044611 nuclear pore inner ring(GO:0044611)
2.0 11.8 GO:0070876 SOSS complex(GO:0070876)
1.8 5.3 GO:0098843 postsynaptic endocytic zone(GO:0098843)
1.2 13.4 GO:0070531 BRCA1-A complex(GO:0070531)
1.0 13.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.8 10.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.8 15.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.7 4.3 GO:0008537 proteasome activator complex(GO:0008537)
0.7 2.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.7 8.1 GO:0034709 methylosome(GO:0034709)
0.6 41.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.5 4.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 4.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.4 50.1 GO:0005882 intermediate filament(GO:0005882)
0.3 15.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.3 4.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 12.3 GO:0015030 Cajal body(GO:0015030)
0.2 35.2 GO:0000922 spindle pole(GO:0000922)
0.2 7.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 56.7 GO:0000793 condensed chromosome(GO:0000793)
0.2 25.5 GO:0005795 Golgi stack(GO:0005795)
0.2 1.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 10.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 20.6 GO:0030315 T-tubule(GO:0030315)
0.2 27.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 1.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 11.4 GO:0005643 nuclear pore(GO:0005643)
0.1 7.8 GO:0072686 mitotic spindle(GO:0072686)
0.1 6.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 11.2 GO:0016459 myosin complex(GO:0016459)
0.1 14.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 6.0 GO:0016235 aggresome(GO:0016235)
0.1 12.2 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 44.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 8.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 9.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 7.7 GO:0032587 ruffle membrane(GO:0032587)
0.1 6.5 GO:0001726 ruffle(GO:0001726)
0.1 3.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 15.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 6.7 GO:0001650 fibrillar center(GO:0001650)
0.0 8.3 GO:0005840 ribosome(GO:0005840)
0.0 50.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 12.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 24.4 GO:0005739 mitochondrion(GO:0005739)
0.0 4.4 GO:0005635 nuclear envelope(GO:0005635)
0.0 111.3 GO:0005634 nucleus(GO:0005634)
0.0 1.2 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 25.5 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
7.7 30.6 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
6.9 20.8 GO:0003896 DNA primase activity(GO:0003896)
6.3 44.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
5.9 23.6 GO:0003883 CTP synthase activity(GO:0003883)
5.7 33.9 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
5.2 25.8 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
5.0 29.8 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
5.0 14.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
4.7 66.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
4.6 27.6 GO:0004832 valine-tRNA ligase activity(GO:0004832)
3.5 24.4 GO:0000405 bubble DNA binding(GO:0000405)
2.9 20.6 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
2.4 19.5 GO:0036310 annealing helicase activity(GO:0036310)
2.4 28.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.3 39.4 GO:0035174 histone serine kinase activity(GO:0035174)
2.0 22.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.7 5.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
1.7 6.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.6 8.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
1.5 4.6 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
1.1 41.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
1.1 7.5 GO:0015616 DNA translocase activity(GO:0015616)
0.9 41.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.9 7.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.9 8.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.6 3.8 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.6 18.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.6 18.2 GO:0043274 phospholipase binding(GO:0043274)
0.6 3.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.5 30.6 GO:0050699 WW domain binding(GO:0050699)
0.5 4.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.5 14.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.4 6.5 GO:0030274 LIM domain binding(GO:0030274)
0.4 7.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.4 4.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 9.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.4 11.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 10.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 13.4 GO:0070840 dynein complex binding(GO:0070840)
0.4 9.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.4 5.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 30.7 GO:0005518 collagen binding(GO:0005518)
0.3 1.2 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.3 6.0 GO:0004697 protein kinase C activity(GO:0004697)
0.3 12.6 GO:0003785 actin monomer binding(GO:0003785)
0.3 7.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 27.7 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.2 2.2 GO:0038132 neuregulin binding(GO:0038132)
0.2 13.4 GO:0003684 damaged DNA binding(GO:0003684)
0.2 3.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 7.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 5.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 11.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 5.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 23.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 1.2 GO:0000150 recombinase activity(GO:0000150)
0.1 3.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 8.6 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 2.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 7.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 8.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 9.7 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 3.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 7.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 6.3 GO:0042393 histone binding(GO:0042393)
0.0 4.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 3.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 5.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 15.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 38.6 GO:0042802 identical protein binding(GO:0042802)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 41.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.5 62.6 PID ATM PATHWAY ATM pathway
1.1 51.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.8 66.8 PID E2F PATHWAY E2F transcription factor network
0.7 27.1 PID ATR PATHWAY ATR signaling pathway
0.4 20.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.4 13.5 ST GAQ PATHWAY G alpha q Pathway
0.4 11.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4 44.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 6.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 18.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 12.5 PID RHOA PATHWAY RhoA signaling pathway
0.2 34.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 5.3 PID ARF 3PATHWAY Arf1 pathway
0.2 4.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 30.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 3.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 7.2 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.1 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 4.7 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 71.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
2.6 30.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.4 30.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.3 36.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
2.1 20.8 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
2.1 18.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.9 27.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.5 28.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
1.4 31.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.2 18.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
1.0 66.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
1.0 25.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.9 27.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.9 98.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.8 9.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.8 27.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.8 5.8 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.8 23.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 58.6 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.5 7.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5 6.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.4 8.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.4 15.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.4 20.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4 9.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.3 9.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 5.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 12.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 8.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 5.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 3.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 12.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 6.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 2.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 4.3 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 3.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 4.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides