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avrg: GSE58827: Dynamics of the Mouse Liver
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Results for E2f6
Z-value: 1.38
Motif logo
Transcription factors associated with E2f6
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
E2f6
|
ENSMUSG00000057469.9 | E2f6 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| E2f6 | mm39_v1_chr12_+_16860931_16861002 | 0.61 | 7.0e-05 | Click! |
Activity profile of E2f6 motif
Sorted Z-values of E2f6 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of E2f6
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 7.8 | GO:0034117 | erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118) |
| 1.5 | 4.6 | GO:0003331 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 1.5 | 7.6 | GO:0072138 | mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) |
| 1.2 | 5.8 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
| 1.0 | 1.0 | GO:0060994 | regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) |
| 1.0 | 2.9 | GO:2000295 | regulation of hydrogen peroxide catabolic process(GO:2000295) |
| 1.0 | 4.8 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 0.9 | 3.7 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
| 0.9 | 3.6 | GO:0015904 | tetracycline transport(GO:0015904) |
| 0.9 | 10.6 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.8 | 4.0 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.8 | 3.1 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.8 | 2.3 | GO:2000474 | regulation of opioid receptor signaling pathway(GO:2000474) |
| 0.7 | 4.5 | GO:0030421 | defecation(GO:0030421) |
| 0.7 | 2.9 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.7 | 6.5 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 0.7 | 4.2 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.7 | 15.9 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 0.7 | 2.0 | GO:0008291 | acetylcholine metabolic process(GO:0008291) neurotransmitter receptor biosynthetic process(GO:0045212) acetate ester metabolic process(GO:1900619) |
| 0.6 | 3.8 | GO:0042117 | monocyte activation(GO:0042117) |
| 0.6 | 1.9 | GO:0045660 | positive regulation of neutrophil differentiation(GO:0045660) |
| 0.6 | 1.9 | GO:0045004 | DNA replication proofreading(GO:0045004) |
| 0.6 | 1.9 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.6 | 2.5 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 0.6 | 1.8 | GO:1900158 | negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
| 0.6 | 0.6 | GO:0001966 | thigmotaxis(GO:0001966) |
| 0.6 | 2.9 | GO:0034224 | cellular response to zinc ion starvation(GO:0034224) |
| 0.6 | 4.6 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.6 | 5.7 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.6 | 3.3 | GO:1902962 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.5 | 1.6 | GO:1990428 | miRNA transport(GO:1990428) |
| 0.5 | 2.0 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 0.5 | 4.1 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
| 0.5 | 2.0 | GO:0090096 | lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
| 0.5 | 0.9 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.5 | 0.9 | GO:0071288 | cellular response to mercury ion(GO:0071288) |
| 0.5 | 8.2 | GO:0033280 | response to vitamin D(GO:0033280) |
| 0.4 | 1.8 | GO:1990091 | sodium-dependent self proteolysis(GO:1990091) |
| 0.4 | 4.0 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.4 | 2.7 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
| 0.4 | 15.3 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.4 | 6.8 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.4 | 1.7 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.4 | 1.3 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
| 0.4 | 3.3 | GO:0044838 | cell quiescence(GO:0044838) |
| 0.4 | 2.5 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
| 0.4 | 3.2 | GO:0006735 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.4 | 1.2 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.4 | 4.3 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.4 | 2.3 | GO:1903438 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.4 | 12.0 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 0.4 | 6.5 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 0.4 | 0.7 | GO:0031938 | regulation of chromatin silencing at telomere(GO:0031938) |
| 0.4 | 3.9 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
| 0.3 | 1.0 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 0.3 | 1.0 | GO:0098884 | postsynaptic neurotransmitter receptor internalization(GO:0098884) |
| 0.3 | 2.1 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.3 | 0.7 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.3 | 3.3 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) |
| 0.3 | 1.0 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.3 | 1.3 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.3 | 1.6 | GO:1905169 | protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171) |
| 0.3 | 1.3 | GO:1902966 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
| 0.3 | 1.5 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.3 | 1.2 | GO:0061534 | gamma-aminobutyric acid secretion, neurotransmission(GO:0061534) |
| 0.3 | 1.5 | GO:2000721 | pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721) |
| 0.3 | 1.2 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 0.3 | 1.2 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.3 | 4.8 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.3 | 0.9 | GO:0042822 | pyridoxal phosphate metabolic process(GO:0042822) |
| 0.3 | 0.3 | GO:1904783 | positive regulation of NMDA glutamate receptor activity(GO:1904783) |
| 0.3 | 1.7 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.3 | 1.4 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
| 0.3 | 1.7 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.3 | 2.3 | GO:0015675 | nickel cation transport(GO:0015675) |
| 0.3 | 0.8 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.3 | 1.4 | GO:1904976 | response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976) |
| 0.3 | 1.1 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.3 | 0.8 | GO:0040030 | regulation of molecular function, epigenetic(GO:0040030) |
| 0.3 | 0.5 | GO:0051660 | establishment of centrosome localization(GO:0051660) |
| 0.3 | 0.5 | GO:0003256 | regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) |
| 0.3 | 2.5 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.3 | 1.0 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.3 | 1.5 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 0.3 | 1.3 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
| 0.2 | 1.0 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
| 0.2 | 3.9 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.2 | 7.3 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.2 | 2.4 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.2 | 0.7 | GO:1903281 | positive regulation of calcium:sodium antiporter activity(GO:1903281) |
| 0.2 | 0.7 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 0.2 | 0.7 | GO:0002017 | regulation of blood volume by renal aldosterone(GO:0002017) |
| 0.2 | 1.9 | GO:0036089 | cleavage furrow formation(GO:0036089) |
| 0.2 | 3.2 | GO:0061072 | iris morphogenesis(GO:0061072) |
| 0.2 | 0.7 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
| 0.2 | 1.1 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
| 0.2 | 2.7 | GO:0030913 | paranodal junction assembly(GO:0030913) |
| 0.2 | 1.3 | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
| 0.2 | 0.4 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
| 0.2 | 1.3 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.2 | 1.7 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.2 | 0.2 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.2 | 1.0 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
| 0.2 | 0.8 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
| 0.2 | 1.2 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) |
| 0.2 | 0.8 | GO:1900756 | establishment of meiotic spindle localization(GO:0051295) protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923) |
| 0.2 | 1.0 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) |
| 0.2 | 2.2 | GO:0015074 | DNA integration(GO:0015074) |
| 0.2 | 2.3 | GO:0002536 | respiratory burst involved in inflammatory response(GO:0002536) |
| 0.2 | 1.5 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.2 | 0.8 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.2 | 1.3 | GO:0090210 | regulation of establishment of blood-brain barrier(GO:0090210) |
| 0.2 | 1.9 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.2 | 7.4 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
| 0.2 | 0.9 | GO:2000327 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.2 | 0.5 | GO:0036015 | response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) |
| 0.2 | 1.3 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.2 | 1.8 | GO:0032264 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
| 0.2 | 0.7 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.2 | 0.8 | GO:0003150 | muscular septum morphogenesis(GO:0003150) |
| 0.2 | 0.5 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.2 | 0.7 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
| 0.2 | 0.5 | GO:0003032 | detection of oxygen(GO:0003032) |
| 0.2 | 0.5 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.2 | 0.6 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 0.2 | 1.6 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.2 | 0.5 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 0.2 | 2.0 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.2 | 3.4 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.2 | 0.5 | GO:0032240 | negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
| 0.1 | 0.4 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.1 | 0.6 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 0.1 | 0.6 | GO:0035385 | Roundabout signaling pathway(GO:0035385) |
| 0.1 | 1.8 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.1 | 2.4 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.1 | 1.0 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 0.1 | 0.6 | GO:0003017 | lymph circulation(GO:0003017) |
| 0.1 | 1.1 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.1 | 1.1 | GO:0006868 | glutamine transport(GO:0006868) |
| 0.1 | 1.5 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.1 | 2.0 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.4 | GO:0010767 | regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) |
| 0.1 | 0.5 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.1 | 0.8 | GO:0021997 | neural plate axis specification(GO:0021997) centriole elongation(GO:0061511) |
| 0.1 | 0.5 | GO:0019042 | viral latency(GO:0019042) |
| 0.1 | 1.2 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.1 | 1.2 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
| 0.1 | 2.4 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.1 | 1.3 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.1 | 1.0 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.1 | 0.2 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.1 | 0.4 | GO:1990117 | release of matrix enzymes from mitochondria(GO:0032976) B cell receptor apoptotic signaling pathway(GO:1990117) |
| 0.1 | 0.8 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.1 | 0.7 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.1 | 2.4 | GO:0001771 | immunological synapse formation(GO:0001771) |
| 0.1 | 0.4 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 0.1 | 1.6 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 0.5 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.1 | 0.6 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.1 | 0.9 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.1 | 4.2 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.1 | 1.8 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.1 | 1.1 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.1 | 0.4 | GO:2001270 | regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.1 | 0.4 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.1 | 0.3 | GO:1904093 | regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093) |
| 0.1 | 1.9 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.1 | 1.2 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 0.1 | 0.5 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.1 | 0.3 | GO:2001200 | positive regulation of dendritic cell differentiation(GO:2001200) |
| 0.1 | 1.1 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.1 | 2.0 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.1 | 0.4 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 0.1 | 0.7 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 0.4 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.1 | 0.4 | GO:1904247 | positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
| 0.1 | 0.7 | GO:0010288 | response to lead ion(GO:0010288) |
| 0.1 | 1.5 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.1 | 0.5 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.1 | 0.4 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.1 | 0.4 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.1 | 0.3 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
| 0.1 | 1.0 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 0.1 | 2.8 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.1 | 0.2 | GO:0010520 | regulation of reciprocal meiotic recombination(GO:0010520) |
| 0.1 | 0.7 | GO:1902510 | regulation of apoptotic DNA fragmentation(GO:1902510) |
| 0.1 | 0.7 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
| 0.1 | 0.3 | GO:0036258 | multivesicular body assembly(GO:0036258) |
| 0.1 | 0.5 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 0.1 | 0.4 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.1 | 2.0 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.1 | 0.6 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 0.9 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 0.9 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.1 | 0.7 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.1 | 8.2 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.1 | 0.2 | GO:0072054 | renal outer medulla development(GO:0072054) |
| 0.1 | 0.7 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.1 | 0.2 | GO:0010615 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 0.1 | 2.1 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.1 | 2.0 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.1 | 0.4 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 0.5 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.1 | 1.6 | GO:0033260 | nuclear DNA replication(GO:0033260) |
| 0.1 | 0.3 | GO:0072737 | response to diamide(GO:0072737) cellular response to diamide(GO:0072738) |
| 0.1 | 0.6 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.1 | 0.8 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.1 | 0.2 | GO:0098749 | cerebellar neuron development(GO:0098749) |
| 0.1 | 1.0 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 0.7 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.7 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
| 0.1 | 0.3 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.1 | 0.6 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.1 | 0.2 | GO:0010958 | regulation of amino acid import(GO:0010958) |
| 0.1 | 0.4 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.1 | 0.4 | GO:0021873 | forebrain neuroblast division(GO:0021873) |
| 0.1 | 0.9 | GO:0033690 | positive regulation of osteoblast proliferation(GO:0033690) |
| 0.1 | 3.2 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.1 | 0.2 | GO:1902269 | positive regulation of polyamine transmembrane transport(GO:1902269) |
| 0.1 | 0.2 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.1 | 1.1 | GO:0050961 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
| 0.1 | 0.2 | GO:1902267 | polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.1 | 0.4 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 0.3 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.1 | 0.3 | GO:0042538 | hyperosmotic salinity response(GO:0042538) |
| 0.1 | 0.2 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 0.1 | 0.7 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.1 | 0.2 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.1 | 0.4 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.1 | 0.4 | GO:0043578 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.1 | 0.5 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.1 | 0.2 | GO:0030210 | heparin biosynthetic process(GO:0030210) |
| 0.1 | 0.4 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.1 | 0.2 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.1 | 0.3 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.1 | 0.4 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.1 | 0.5 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.9 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.1 | 0.3 | GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
| 0.0 | 0.1 | GO:2000832 | negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
| 0.0 | 0.1 | GO:0021886 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
| 0.0 | 0.1 | GO:0021570 | rhombomere 4 development(GO:0021570) |
| 0.0 | 0.3 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 0.2 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.0 | 0.1 | GO:1903251 | multi-ciliated epithelial cell differentiation(GO:1903251) |
| 0.0 | 0.5 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.0 | 0.2 | GO:0030423 | production of siRNA involved in RNA interference(GO:0030422) targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087) negative regulation of defense response to virus by host(GO:0050689) |
| 0.0 | 7.0 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
| 0.0 | 0.9 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.0 | 0.9 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.0 | 0.3 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.0 | 0.1 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.0 | 0.4 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 1.1 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.0 | 0.3 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
| 0.0 | 0.3 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.0 | 1.9 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.0 | 0.2 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.0 | 0.4 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.0 | 0.3 | GO:0033578 | protein glycosylation in Golgi(GO:0033578) |
| 0.0 | 1.7 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.0 | 0.7 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.0 | 1.0 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.8 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.0 | 0.6 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 1.0 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.0 | 0.4 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
| 0.0 | 0.7 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.0 | 0.4 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.0 | 0.1 | GO:0003360 | brainstem development(GO:0003360) |
| 0.0 | 3.1 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.6 | GO:0045005 | DNA-dependent DNA replication maintenance of fidelity(GO:0045005) |
| 0.0 | 0.2 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 0.0 | 0.2 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 0.0 | 0.8 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.3 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.0 | 1.9 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 2.1 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.0 | 1.5 | GO:0006378 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 0.0 | 0.4 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.0 | 0.5 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.0 | 1.4 | GO:0030865 | cortical cytoskeleton organization(GO:0030865) |
| 0.0 | 0.2 | GO:1904354 | negative regulation of telomere capping(GO:1904354) |
| 0.0 | 0.3 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.0 | 0.3 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.0 | 0.4 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.0 | 0.3 | GO:0009048 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.0 | 0.1 | GO:0099543 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) |
| 0.0 | 0.5 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 0.0 | 0.3 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.0 | 0.1 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.0 | 0.1 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
| 0.0 | 0.1 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 0.0 | 0.2 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.0 | 1.2 | GO:0048169 | regulation of long-term neuronal synaptic plasticity(GO:0048169) |
| 0.0 | 0.1 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.0 | 0.2 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.0 | 0.5 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.0 | 0.3 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
| 0.0 | 0.3 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.0 | 0.5 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.5 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
| 0.0 | 0.1 | GO:0001828 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.0 | 0.1 | GO:0036343 | psychomotor behavior(GO:0036343) |
| 0.0 | 0.3 | GO:0010835 | regulation of protein ADP-ribosylation(GO:0010835) |
| 0.0 | 0.3 | GO:0039529 | RIG-I signaling pathway(GO:0039529) |
| 0.0 | 0.1 | GO:0086045 | membrane depolarization during AV node cell action potential(GO:0086045) |
| 0.0 | 0.6 | GO:0070193 | synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193) |
| 0.0 | 0.6 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.9 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.0 | 0.1 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.0 | 0.9 | GO:2000273 | positive regulation of receptor activity(GO:2000273) |
| 0.0 | 0.2 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.0 | 0.6 | GO:0051205 | protein insertion into membrane(GO:0051205) |
| 0.0 | 0.4 | GO:0051569 | regulation of histone H3-K4 methylation(GO:0051569) |
| 0.0 | 0.1 | GO:1901740 | negative regulation of myoblast fusion(GO:1901740) |
| 0.0 | 0.7 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.2 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.0 | 0.1 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.5 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.0 | 0.0 | GO:0051329 | interphase(GO:0051325) mitotic interphase(GO:0051329) mitotic cell cycle phase(GO:0098763) |
| 0.0 | 0.3 | GO:0061577 | calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) |
| 0.0 | 0.1 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 0.0 | 0.0 | GO:1904954 | canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954) |
| 0.0 | 0.4 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.0 | 0.4 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.3 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 0.0 | 0.3 | GO:0036260 | 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260) |
| 0.0 | 0.1 | GO:0031179 | peptide modification(GO:0031179) |
| 0.0 | 0.2 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.0 | 0.3 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 2.7 | GO:1990823 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.0 | 0.2 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.0 | 0.2 | GO:0031119 | rRNA pseudouridine synthesis(GO:0031118) tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.0 | 0.0 | GO:0023035 | CD40 signaling pathway(GO:0023035) |
| 0.0 | 0.2 | GO:0032986 | protein-DNA complex disassembly(GO:0032986) |
| 0.0 | 0.8 | GO:0050710 | negative regulation of cytokine secretion(GO:0050710) |
| 0.0 | 0.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.2 | GO:0098534 | centriole replication(GO:0007099) centriole assembly(GO:0098534) |
| 0.0 | 0.3 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.0 | 0.1 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.0 | 0.1 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
| 0.0 | 0.1 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.0 | 0.1 | GO:0003195 | tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.0 | 0.5 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.0 | 0.5 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.0 | 0.4 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.0 | 0.3 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
| 0.0 | 0.2 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.0 | 1.2 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 0.1 | GO:0022028 | tangential migration from the subventricular zone to the olfactory bulb(GO:0022028) |
| 0.0 | 0.3 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
| 0.0 | 0.1 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.0 | 0.2 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
| 0.0 | 0.1 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.0 | 0.2 | GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) |
| 0.0 | 0.1 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 13.9 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 1.5 | 5.8 | GO:0001740 | Barr body(GO:0001740) |
| 1.0 | 15.4 | GO:0042555 | MCM complex(GO:0042555) |
| 0.9 | 7.6 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.9 | 7.1 | GO:0008091 | spectrin(GO:0008091) |
| 0.8 | 2.3 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.7 | 2.9 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.6 | 2.6 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.6 | 5.0 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.5 | 3.7 | GO:0005638 | lamin filament(GO:0005638) |
| 0.5 | 1.5 | GO:0000811 | GINS complex(GO:0000811) |
| 0.5 | 3.3 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.5 | 5.2 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.4 | 3.1 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.4 | 1.2 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.4 | 1.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.4 | 1.9 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.3 | 3.8 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.3 | 3.1 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.3 | 1.9 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.3 | 8.7 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.3 | 0.9 | GO:0034455 | t-UTP complex(GO:0034455) |
| 0.3 | 1.6 | GO:0099522 | region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524) |
| 0.3 | 2.6 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.2 | 0.7 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.2 | 3.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.2 | 0.7 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.2 | 0.7 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.2 | 0.7 | GO:0034066 | RIC1-RGP1 guanyl-nucleotide exchange factor complex(GO:0034066) |
| 0.2 | 2.5 | GO:0000796 | condensin complex(GO:0000796) |
| 0.2 | 2.7 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.2 | 1.0 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.2 | 0.9 | GO:0044308 | axonal spine(GO:0044308) |
| 0.2 | 2.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.2 | 0.5 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.2 | 0.7 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.2 | 1.5 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.2 | 3.3 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 3.0 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.1 | 0.6 | GO:0032127 | dense core granule membrane(GO:0032127) |
| 0.1 | 0.4 | GO:0097132 | cyclin D2-CDK6 complex(GO:0097132) |
| 0.1 | 1.7 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.1 | 0.7 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.1 | 9.6 | GO:0000791 | euchromatin(GO:0000791) |
| 0.1 | 3.9 | GO:0005605 | basal lamina(GO:0005605) |
| 0.1 | 1.0 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 1.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 0.7 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.1 | 7.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 0.7 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 0.1 | 0.7 | GO:0043293 | apoptosome(GO:0043293) |
| 0.1 | 0.4 | GO:0044302 | dentate gyrus mossy fiber(GO:0044302) |
| 0.1 | 1.2 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 1.9 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.1 | 0.4 | GO:0097144 | BAX complex(GO:0097144) |
| 0.1 | 0.6 | GO:0098645 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.1 | 1.5 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 0.8 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.1 | 4.9 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 0.7 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 0.3 | GO:0070939 | Dsl1p complex(GO:0070939) RZZ complex(GO:1990423) |
| 0.1 | 14.4 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.1 | 1.8 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.1 | 1.5 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.1 | 1.5 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 0.2 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.1 | 1.8 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.1 | 1.2 | GO:0000801 | central element(GO:0000801) |
| 0.1 | 0.9 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.1 | 0.3 | GO:0097361 | CIA complex(GO:0097361) |
| 0.1 | 0.9 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.1 | 0.3 | GO:0070877 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
| 0.1 | 0.5 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.1 | 0.9 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.1 | 1.0 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.1 | 0.5 | GO:0089701 | U2AF(GO:0089701) |
| 0.1 | 0.4 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.1 | 1.7 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 1.3 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 4.2 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 1.9 | GO:0045120 | pronucleus(GO:0045120) |
| 0.1 | 0.9 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 2.8 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.1 | 0.4 | GO:0001652 | granular component(GO:0001652) |
| 0.1 | 1.0 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.1 | 0.9 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 4.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.1 | 8.1 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 0.3 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.1 | 2.9 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 1.1 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.1 | 0.3 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 1.0 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 0.6 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 2.1 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 0.4 | GO:0098536 | deuterosome(GO:0098536) |
| 0.1 | 4.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 0.2 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.1 | 0.5 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 0.4 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 0.7 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.0 | 0.2 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 1.4 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 0.0 | 0.2 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.0 | 3.8 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 0.7 | GO:0031091 | platelet alpha granule(GO:0031091) |
| 0.0 | 2.8 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 1.0 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 1.1 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 0.5 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 1.2 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.0 | 0.9 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.0 | 0.6 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 1.0 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 3.8 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.9 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 0.4 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 1.1 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.3 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 0.4 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 2.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 2.4 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 3.6 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.0 | 0.4 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.2 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.3 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.0 | 3.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 0.1 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.0 | 1.7 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.0 | 1.1 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.2 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 2.2 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.5 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 0.2 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.0 | 2.7 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 1.4 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.0 | 0.8 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 1.0 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 1.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 6.7 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 1.9 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.2 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.0 | 0.6 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 0.2 | GO:0032797 | SMN complex(GO:0032797) |
| 0.0 | 0.1 | GO:0070110 | ciliary neurotrophic factor receptor complex(GO:0070110) |
| 0.0 | 0.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 1.7 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 1.5 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.3 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.1 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 1.0 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.4 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.7 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.6 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 13.9 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 2.2 | 6.5 | GO:0052894 | norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895) |
| 1.1 | 3.2 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 1.0 | 3.1 | GO:0003896 | DNA primase activity(GO:0003896) |
| 1.0 | 3.0 | GO:0031755 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 0.9 | 5.7 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.9 | 3.6 | GO:0008493 | tetracycline transporter activity(GO:0008493) |
| 0.7 | 2.0 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.6 | 5.2 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 0.6 | 3.8 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.6 | 1.7 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.5 | 1.6 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.5 | 1.0 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.5 | 4.3 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.5 | 1.4 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.4 | 2.2 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
| 0.4 | 1.3 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 0.4 | 1.3 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.4 | 1.2 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.4 | 3.0 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.4 | 1.1 | GO:0051916 | granulocyte colony-stimulating factor binding(GO:0051916) |
| 0.4 | 0.7 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.3 | 2.3 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.3 | 7.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.3 | 0.9 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.3 | 4.3 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.3 | 3.3 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.3 | 1.2 | GO:0004096 | catalase activity(GO:0004096) |
| 0.3 | 12.7 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.3 | 2.3 | GO:0015099 | nickel cation transmembrane transporter activity(GO:0015099) |
| 0.3 | 2.3 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.3 | 1.1 | GO:0086077 | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
| 0.3 | 12.1 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.3 | 2.9 | GO:1903136 | cuprous ion binding(GO:1903136) |
| 0.3 | 0.8 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.3 | 1.3 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.3 | 1.5 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.3 | 1.8 | GO:1990715 | mRNA CDS binding(GO:1990715) |
| 0.2 | 2.5 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.2 | 2.7 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.2 | 1.4 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.2 | 2.3 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.2 | 0.7 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.2 | 1.2 | GO:1990188 | euchromatin binding(GO:1990188) |
| 0.2 | 5.0 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.2 | 0.7 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.2 | 2.7 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.2 | 1.9 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.2 | 1.0 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.2 | 3.3 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.2 | 2.3 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 0.2 | 1.0 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.2 | 8.5 | GO:0043394 | proteoglycan binding(GO:0043394) |
| 0.2 | 1.0 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
| 0.2 | 1.9 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.2 | 4.4 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.2 | 1.1 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.2 | 1.8 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.2 | 0.7 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.2 | 1.9 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.2 | 0.9 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.2 | 0.7 | GO:0070137 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.2 | 1.5 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 1.5 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.2 | 2.1 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.2 | 2.6 | GO:0031386 | protein tag(GO:0031386) |
| 0.2 | 1.1 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.2 | 1.6 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.2 | 6.2 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.2 | 1.1 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.2 | 4.7 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.2 | 0.9 | GO:0045340 | mercury ion binding(GO:0045340) |
| 0.2 | 0.5 | GO:0070540 | stearic acid binding(GO:0070540) |
| 0.1 | 4.1 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 1.7 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.1 | 0.6 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.1 | 1.7 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 0.7 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 0.1 | 1.1 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 0.7 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.1 | 1.2 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 0.1 | 0.9 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.1 | 1.9 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.1 | 0.9 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 2.1 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 1.8 | GO:0031432 | titin binding(GO:0031432) |
| 0.1 | 0.7 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 0.5 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.1 | 4.6 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 7.7 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 0.8 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.1 | 0.4 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.1 | 2.4 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.1 | 4.7 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 0.6 | GO:0031781 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
| 0.1 | 1.3 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.1 | 0.4 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 0.1 | 0.3 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 0.1 | 3.9 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 1.4 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 0.4 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.1 | 1.3 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.1 | 0.5 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.1 | 0.2 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.1 | 0.8 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.1 | 0.4 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 0.1 | 0.2 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.1 | 1.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.1 | 0.5 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 2.2 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.1 | 0.6 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.1 | 0.9 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.1 | 1.4 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 0.3 | GO:0051435 | BH4 domain binding(GO:0051435) |
| 0.1 | 0.3 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.1 | 0.2 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.1 | 0.7 | GO:0005113 | patched binding(GO:0005113) |
| 0.1 | 0.1 | GO:0086059 | voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059) |
| 0.1 | 0.4 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.1 | 0.4 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
| 0.1 | 3.5 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 1.8 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 0.5 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.1 | 3.6 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 0.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 1.2 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 1.2 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 3.9 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 0.2 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 0.1 | 0.7 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.1 | 0.2 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.1 | 0.2 | GO:0042979 | ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979) |
| 0.1 | 0.5 | GO:0030619 | U1 snRNA binding(GO:0030619) |
| 0.1 | 0.2 | GO:0032139 | Y-form DNA binding(GO:0000403) dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142) |
| 0.1 | 1.2 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
| 0.1 | 0.5 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.1 | 0.5 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.1 | 1.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 1.9 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.1 | 1.4 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.5 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.1 | 0.7 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.9 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 0.4 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 1.7 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 1.1 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.7 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 1.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.7 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 0.9 | GO:0010181 | FMN binding(GO:0010181) |
| 0.0 | 4.1 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.3 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.0 | 1.6 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.4 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.0 | 0.2 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 0.0 | 1.9 | GO:0061650 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.0 | 0.2 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.0 | 0.2 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
| 0.0 | 0.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.2 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.0 | 1.1 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.0 | 0.4 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 1.1 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 1.9 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.0 | 0.7 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 2.9 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.7 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 0.1 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.0 | 0.3 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 1.2 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 0.8 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 2.2 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 0.6 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 0.7 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.1 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.0 | 0.4 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 0.3 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 3.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.4 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.5 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.0 | 0.7 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 1.6 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 0.5 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.2 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.0 | 0.1 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.0 | 0.1 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.0 | 1.3 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 1.0 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.3 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.1 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 0.0 | 0.6 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.0 | 0.7 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.4 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.3 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.0 | 0.4 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 0.5 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.0 | 0.9 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.1 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 0.0 | 0.8 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.2 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.0 | 0.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 1.6 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.2 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.0 | 0.7 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.7 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.1 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.0 | 0.1 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.0 | 0.2 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.0 | 0.1 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) |
| 0.0 | 0.5 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.0 | 0.1 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
| 0.0 | 0.1 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.1 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 9.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.4 | 19.2 | PID ATR PATHWAY | ATR signaling pathway |
| 0.2 | 3.3 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.2 | 20.8 | PID E2F PATHWAY | E2F transcription factor network |
| 0.2 | 10.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.2 | 8.1 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 7.5 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 0.3 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.1 | 12.5 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 1.1 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.1 | 3.2 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 2.2 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 0.9 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 2.2 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.1 | 3.0 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.1 | 0.2 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.1 | 2.0 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 1.5 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 3.2 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 1.9 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 1.5 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 6.4 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 1.6 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 1.1 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 1.9 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.1 | 2.6 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.1 | 3.7 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 0.1 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 0.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 2.5 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 1.1 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.9 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 1.2 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 1.3 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 1.7 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.7 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.0 | 0.7 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.9 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 1.1 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 2.6 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.7 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 2.4 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 1.9 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 3.3 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.8 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 1.7 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.1 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 0.6 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.5 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 0.2 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.0 | 0.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.2 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 0.5 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.7 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.7 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 0.3 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 0.5 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.6 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.7 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.0 | 1.2 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 3.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.4 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.3 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 3.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.1 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 16.8 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.8 | 16.9 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.7 | 11.5 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.5 | 1.9 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.4 | 7.0 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.3 | 5.3 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.2 | 3.4 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.2 | 6.6 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.2 | 3.3 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.2 | 2.3 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.2 | 9.6 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.2 | 3.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 3.2 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 8.7 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 2.0 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.1 | 2.3 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 6.0 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.1 | 4.1 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 2.5 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 2.9 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.1 | 1.0 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.1 | 0.3 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.1 | 1.1 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.1 | 6.3 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.1 | 3.6 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 4.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 3.2 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.1 | 4.9 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.1 | 1.0 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.1 | 8.9 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 1.9 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 1.8 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.1 | 0.7 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 8.4 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 3.2 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.1 | 0.5 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.1 | 0.4 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 1.5 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 2.5 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 2.0 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 0.4 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.1 | 0.7 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 0.5 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.1 | 0.5 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.1 | 2.1 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 2.5 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 1.5 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 3.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 1.8 | REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.1 | 0.4 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 0.5 | REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| 0.0 | 0.5 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.6 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 3.2 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 1.4 | REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
| 0.0 | 0.6 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 1.0 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 0.3 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 0.5 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 2.5 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 4.9 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 0.5 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 1.0 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.6 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 10.3 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.5 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 0.2 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 1.1 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 1.0 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.4 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 0.4 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.5 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.0 | 1.0 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.3 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 0.3 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.2 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 0.0 | 0.4 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.4 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.3 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 0.2 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 0.3 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 0.0 | 0.2 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.2 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 0.3 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.0 | 0.2 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.0 | 0.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.1 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.2 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |