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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Egr1

Z-value: 1.97

Motif logo

Transcription factors associated with Egr1

Gene Symbol Gene ID Gene Info
ENSMUSG00000038418.8 Egr1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Egr1mm39_v1_chr18_+_34994253_34994268-0.076.9e-01Click!

Activity profile of Egr1 motif

Sorted Z-values of Egr1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Egr1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_+_109419371 11.61 ENSMUST00000109844.11
ENSMUST00000109842.9
ENSMUST00000109843.8
delta like non-canonical Notch ligand 1
chr12_-_76756772 9.99 ENSMUST00000166101.2
spectrin beta, erythrocytic
chr12_+_109419575 9.53 ENSMUST00000173539.8
ENSMUST00000109841.9
delta like non-canonical Notch ligand 1
chr10_-_80413119 7.45 ENSMUST00000038558.9
Kruppel-like factor 16
chr12_+_109419454 7.10 ENSMUST00000109846.11
delta like non-canonical Notch ligand 1
chr6_-_60805873 6.98 ENSMUST00000114268.5
synuclein, alpha
chr6_+_121613177 6.96 ENSMUST00000032203.9
alpha-2-macroglobulin
chr14_-_70873385 6.80 ENSMUST00000228295.2
ENSMUST00000022695.16
dematin actin binding protein
chr3_-_88417251 6.45 ENSMUST00000149068.2
lamin A
chr16_+_93680783 6.39 ENSMUST00000023666.11
ENSMUST00000117099.8
chromatin assembly factor 1, subunit B (p60)
chr7_-_142213219 6.37 ENSMUST00000121128.8
insulin-like growth factor 2
chr2_+_117942357 5.92 ENSMUST00000039559.9
thrombospondin 1
chr12_-_32111214 5.80 ENSMUST00000003079.12
ENSMUST00000036497.16
protein kinase, cAMP dependent regulatory, type II beta
chr17_+_37180437 5.75 ENSMUST00000060524.11
tripartite motif-containing 10
chr9_-_37464200 5.43 ENSMUST00000065668.12
neurogranin
chr3_-_100396635 5.39 ENSMUST00000061455.9
terminal nucleotidyltransferase 5C
chr7_-_126303947 5.32 ENSMUST00000032949.14
coronin, actin binding protein 1A
chr3_-_127689890 4.76 ENSMUST00000057198.9
ENSMUST00000199273.2
family with sequence similarity 241, member A
chrX_+_7708295 4.71 ENSMUST00000115667.10
ENSMUST00000115668.10
ENSMUST00000115665.2
OTU domain containing 5
chr4_-_43045685 4.59 ENSMUST00000107956.8
ENSMUST00000107957.8
family with sequence similarity 214, member B
chr4_+_118965908 4.53 ENSMUST00000030398.10
solute carrier family 2 (facilitated glucose transporter), member 1
chr10_-_81214293 4.50 ENSMUST00000140901.8
fizzy and cell division cycle 20 related 1
chr7_-_126303351 4.39 ENSMUST00000106364.8
coronin, actin binding protein 1A
chr4_-_43046196 4.20 ENSMUST00000036462.12
family with sequence similarity 214, member B
chr4_+_118965992 3.94 ENSMUST00000134105.8
ENSMUST00000144329.8
ENSMUST00000208090.2
solute carrier family 2 (facilitated glucose transporter), member 1
chr7_-_126014027 3.82 ENSMUST00000032968.7
ENSMUST00000206325.2
CD19 antigen
chr6_+_142702403 3.74 ENSMUST00000032419.9
cytidine monophospho-N-acetylneuraminic acid synthetase
chr8_+_84724130 3.70 ENSMUST00000095228.5
sterile alpha motif domain containing 1
chr7_-_37806912 3.50 ENSMUST00000108023.10
cyclin E1
chr16_+_49676130 3.39 ENSMUST00000230641.2
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr10_-_12839995 3.36 ENSMUST00000219727.2
ENSMUST00000163425.9
ENSMUST00000042861.7
ENSMUST00000218685.2
syntaxin 11
chr13_-_55661240 3.31 ENSMUST00000069929.13
ENSMUST00000069968.13
ENSMUST00000131306.8
ENSMUST00000046246.13
PDZ and LIM domain 7
chrX_-_74174608 3.28 ENSMUST00000033775.9
membrane protein, palmitoylated
chrX_-_74174450 3.18 ENSMUST00000114092.8
ENSMUST00000132501.8
ENSMUST00000153318.8
ENSMUST00000155742.2
membrane protein, palmitoylated
chr1_+_135060431 3.07 ENSMUST00000187985.7
ENSMUST00000049449.11
protein tyrosine phosphatase, non-receptor type 7
chr9_+_62746055 3.06 ENSMUST00000034776.13
ceroid-lipofuscinosis, neuronal 6
chr3_-_86827640 3.04 ENSMUST00000195561.6
doublecortin-like kinase 2
chr7_+_120442773 3.00 ENSMUST00000143279.3
ENSMUST00000106489.9
eukaryotic elongation factor-2 kinase
chr7_-_126625617 2.93 ENSMUST00000032916.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_+_99184645 2.92 ENSMUST00000098266.9
ENSMUST00000179755.8
arrestin, beta 1
chr4_-_133615075 2.90 ENSMUST00000003741.16
ENSMUST00000105894.11
ribosomal protein S6 kinase polypeptide 1
chrX_+_7708034 2.90 ENSMUST00000033494.16
ENSMUST00000115666.8
OTU domain containing 5
chr1_-_59012579 2.86 ENSMUST00000173590.2
ENSMUST00000027186.12
trafficking protein, kinesin binding 2
chr15_+_79231720 2.85 ENSMUST00000096350.11
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr5_-_33432310 2.80 ENSMUST00000201372.3
ENSMUST00000202962.4
ENSMUST00000201575.4
ENSMUST00000202868.4
ENSMUST00000079746.10
C-terminal binding protein 1
chr2_+_118644717 2.74 ENSMUST00000028803.14
ENSMUST00000126045.8
kinetochore-localized astrin/SPAG5 binding
chr16_-_18448614 2.72 ENSMUST00000231956.2
ENSMUST00000096987.7
septin 5
chrX_+_161543384 2.69 ENSMUST00000033720.12
ENSMUST00000112327.8
retinoblastoma binding protein 7, chromatin remodeling factor
chrX_+_9138995 2.68 ENSMUST00000015486.7
X-linked Kx blood group
chr16_+_49675969 2.68 ENSMUST00000229101.2
ENSMUST00000230836.2
ENSMUST00000229206.2
ENSMUST00000084838.14
ENSMUST00000230281.2
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr11_+_117006020 2.57 ENSMUST00000103026.10
ENSMUST00000090433.6
SEC14-like lipid binding 1
chrX_-_74174524 2.55 ENSMUST00000114091.8
membrane protein, palmitoylated
chr15_-_36609208 2.55 ENSMUST00000001809.15
poly(A) binding protein, cytoplasmic 1
chr10_-_80269436 2.54 ENSMUST00000105346.10
ENSMUST00000020377.13
ENSMUST00000105340.8
ENSMUST00000020379.13
ENSMUST00000105344.8
ENSMUST00000105342.8
ENSMUST00000105345.10
ENSMUST00000105343.8
transcription factor 3
chr9_-_57169830 2.52 ENSMUST00000215298.2
RIKEN cDNA 1700017B05 gene
chr9_-_57169872 2.50 ENSMUST00000213199.2
ENSMUST00000034846.7
RIKEN cDNA 1700017B05 gene
chr15_-_64184485 2.49 ENSMUST00000177083.8
ENSMUST00000177371.8
ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr6_-_70769135 2.49 ENSMUST00000066134.6
ribose 5-phosphate isomerase A
chr9_+_44245981 2.45 ENSMUST00000052686.4
H2A.X variant histone
chr9_+_106080307 2.42 ENSMUST00000024047.12
ENSMUST00000216348.2
twinfilin actin binding protein 2
chr4_-_133856025 2.42 ENSMUST00000105879.2
ENSMUST00000030651.9
SH3 domain binding glutamic acid-rich protein-like 3
chr2_+_118644675 2.37 ENSMUST00000110842.8
kinetochore-localized astrin/SPAG5 binding
chr4_-_133694607 2.35 ENSMUST00000105893.8
high mobility group nucleosomal binding domain 2
chr15_+_88746380 2.34 ENSMUST00000042818.11
proviral integration site 3
chr14_-_47514248 2.32 ENSMUST00000187531.8
ENSMUST00000111790.2
WD repeat and HMG-box DNA binding protein 1
chr7_+_26958150 2.32 ENSMUST00000079258.7
numb-like
chr12_+_85645801 2.30 ENSMUST00000177587.9
Jun dimerization protein 2
chrX_+_161543423 2.28 ENSMUST00000112326.8
retinoblastoma binding protein 7, chromatin remodeling factor
chr11_+_117005958 2.24 ENSMUST00000021177.15
SEC14-like lipid binding 1
chr8_-_123278054 2.20 ENSMUST00000156333.9
ENSMUST00000067252.14
piezo-type mechanosensitive ion channel component 1
chr12_+_85646162 2.20 ENSMUST00000050687.14
Jun dimerization protein 2
chr12_+_108602008 2.18 ENSMUST00000172409.2
Ena-vasodilator stimulated phosphoprotein
chr7_-_126625657 2.17 ENSMUST00000205568.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chrX_-_72703330 2.08 ENSMUST00000114473.8
ENSMUST00000002087.14
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr13_+_55593116 2.08 ENSMUST00000001115.16
ENSMUST00000224995.2
ENSMUST00000225925.2
ENSMUST00000099482.5
ENSMUST00000224118.2
G protein-coupled receptor kinase 6
chr6_+_72074545 2.07 ENSMUST00000069994.11
ENSMUST00000114112.4
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr12_-_36206780 2.02 ENSMUST00000223382.2
ENSMUST00000020856.6
basic leucine zipper and W2 domains 2
chr5_-_110987604 2.01 ENSMUST00000056937.12
HscB iron-sulfur cluster co-chaperone
chr12_+_108601963 1.99 ENSMUST00000223109.2
Ena-vasodilator stimulated phosphoprotein
chr2_+_118644475 1.99 ENSMUST00000134661.8
kinetochore-localized astrin/SPAG5 binding
chr5_+_143608194 1.98 ENSMUST00000116456.10
cytohesin 3
chr4_-_133694543 1.97 ENSMUST00000123234.8
high mobility group nucleosomal binding domain 2
chr15_+_81119700 1.94 ENSMUST00000166855.3
melanin-concentrating hormone receptor 1
chr6_+_72074718 1.93 ENSMUST00000187007.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr11_-_120238917 1.92 ENSMUST00000106215.11
actin, gamma, cytoplasmic 1
chr14_+_24540745 1.91 ENSMUST00000112384.10
ribosomal protein S24
chr5_-_107873883 1.90 ENSMUST00000159263.3
growth factor independent 1 transcription repressor
chr7_+_29991101 1.90 ENSMUST00000150892.2
ENSMUST00000126216.2
ENSMUST00000014065.16
CAP-GLY domain containing linker protein 3
chr15_+_76131020 1.90 ENSMUST00000229380.2
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr9_+_54606832 1.86 ENSMUST00000070070.8
DnaJ heat shock protein family (Hsp40) member A4
chr2_-_34262012 1.85 ENSMUST00000113132.9
ENSMUST00000040638.15
pre B cell leukemia homeobox 3
chr14_+_24540777 1.84 ENSMUST00000169826.3
ENSMUST00000225023.2
ENSMUST00000223999.2
ribosomal protein S24
chr5_-_137530214 1.84 ENSMUST00000140139.2
guanine nucleotide binding protein (G protein), beta 2
chr18_-_77855446 1.80 ENSMUST00000048192.9
HAUS augmin-like complex, subunit 1
chr5_-_148988413 1.78 ENSMUST00000093196.11
high mobility group box 1
chr5_-_114046746 1.78 ENSMUST00000004646.13
coronin, actin binding protein 1C
chr4_-_93223746 1.77 ENSMUST00000066774.6
tumor suppressor candidate 1
chr7_-_16007542 1.75 ENSMUST00000169612.3
InaF motif containing 1
chr7_+_127566629 1.74 ENSMUST00000106251.10
ENSMUST00000077609.12
ENSMUST00000121616.9
fused in sarcoma
chr8_+_85753452 1.74 ENSMUST00000047281.10
telomerase RNA component interacting RNase
chr7_+_139673300 1.69 ENSMUST00000026540.9
proline-rich acidic protein 1
chr3_-_83947416 1.68 ENSMUST00000192095.6
ENSMUST00000191758.6
ENSMUST00000052342.9
transmembrane 131 like
chr7_+_27186335 1.67 ENSMUST00000008528.8
SERTA domain containing 1
chr15_+_78784043 1.65 ENSMUST00000001226.11
SH3-domain binding protein 1
chr13_+_55517545 1.65 ENSMUST00000063771.14
regulator of G-protein signaling 14
chr3_+_103009920 1.64 ENSMUST00000173206.8
DENN/MADD domain containing 2C
chr15_+_78783867 1.64 ENSMUST00000134703.8
ENSMUST00000061239.14
ENSMUST00000109698.9
predicted gene, 49510
SH3-domain binding protein 1
chr1_-_180641430 1.63 ENSMUST00000162814.8
H3.3 histone A
chr14_+_24540815 1.63 ENSMUST00000224568.2
ribosomal protein S24
chr4_-_135714465 1.62 ENSMUST00000105851.9
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr4_+_131600918 1.57 ENSMUST00000053819.6
serine and arginine-rich splicing factor 4
chr9_+_54606144 1.53 ENSMUST00000120452.8
DnaJ heat shock protein family (Hsp40) member A4
chr6_+_28423539 1.52 ENSMUST00000020717.12
ENSMUST00000169841.2
ADP-ribosylation factor 5
chr7_-_126625739 1.51 ENSMUST00000205461.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr10_-_80156337 1.51 ENSMUST00000020341.9
RIKEN cDNA 2310011J03 gene
chrX_-_72703652 1.50 ENSMUST00000114472.8
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr14_+_51162635 1.50 ENSMUST00000128395.2
apurinic/apyrimidinic endonuclease 1
chrX_+_48559327 1.48 ENSMUST00000114904.10
Rho GTPase activating protein 36
chr1_-_75119277 1.47 ENSMUST00000168720.8
ENSMUST00000041213.12
ENSMUST00000189809.2
cyclin Pas1/PHO80 domain containing 1
chr9_+_54606798 1.46 ENSMUST00000154690.8
DnaJ heat shock protein family (Hsp40) member A4
chr5_-_110987441 1.45 ENSMUST00000145318.2
HscB iron-sulfur cluster co-chaperone
chr6_+_4747298 1.45 ENSMUST00000166678.2
ENSMUST00000176204.8
paternally expressed 10
chr16_-_18448454 1.45 ENSMUST00000231622.2
septin 5
chr17_+_29020064 1.44 ENSMUST00000004985.11
bromodomain and PHD finger containing, 3
chr12_-_36206750 1.44 ENSMUST00000221388.2
basic leucine zipper and W2 domains 2
chr19_+_6952580 1.44 ENSMUST00000237084.2
ENSMUST00000236218.2
ENSMUST00000237235.2
protein phosphatase 1, regulatory inhibitor subunit 14B
chr11_-_100331754 1.43 ENSMUST00000107397.2
ENSMUST00000092689.9
5'-nucleotidase, cytosolic IIIB
chr1_-_97589365 1.42 ENSMUST00000153115.8
ENSMUST00000142234.2
macrophage immunometabolism regulator
chr2_+_69652714 1.41 ENSMUST00000053087.4
kelch-like 23
chr4_-_133695204 1.39 ENSMUST00000100472.10
ENSMUST00000136327.2
high mobility group nucleosomal binding domain 2
chr8_+_40876827 1.37 ENSMUST00000049389.11
ENSMUST00000128166.8
ENSMUST00000167766.2
zinc finger, DHHC domain containing 2
chr5_+_100187844 1.37 ENSMUST00000169390.8
ENSMUST00000031268.8
enolase-phosphatase 1
chr2_-_34803988 1.37 ENSMUST00000028232.7
ENSMUST00000202907.2
PHD finger protein 19
chr2_+_145009625 1.36 ENSMUST00000110007.8
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr7_-_126102579 1.35 ENSMUST00000040202.15
ataxin 2-like
chr4_+_47474652 1.32 ENSMUST00000065678.6
Sec61 beta subunit
chr17_+_35113490 1.32 ENSMUST00000052778.10
zinc finger and BTB domain containing 12
chr19_+_5618029 1.31 ENSMUST00000235575.2
ENSMUST00000235542.2
adaptor-related protein complex 5, beta 1 subunit
chr1_-_181039509 1.30 ENSMUST00000162819.9
ENSMUST00000237749.2
WD repeat domain 26
chr6_-_88818832 1.30 ENSMUST00000032169.8
ankyrin repeat and BTB (POZ) domain containing 1
chr16_+_93680846 1.30 ENSMUST00000142316.2
chromatin assembly factor 1, subunit B (p60)
chrX_-_156275231 1.29 ENSMUST00000112529.8
spermine synthase
chr6_-_30936013 1.29 ENSMUST00000101589.5
Kruppel-like factor 14
chr19_+_6952319 1.28 ENSMUST00000070850.8
protein phosphatase 1, regulatory inhibitor subunit 14B
chr11_+_70323452 1.27 ENSMUST00000084954.13
ENSMUST00000108568.10
ENSMUST00000079056.9
ENSMUST00000102564.11
ENSMUST00000124943.8
ENSMUST00000150076.8
ENSMUST00000102563.2
arrestin, beta 2
chr15_+_76130947 1.27 ENSMUST00000229772.2
ENSMUST00000230347.2
ENSMUST00000023225.8
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr13_-_98453475 1.25 ENSMUST00000022163.15
ENSMUST00000152704.8
basic transcription factor 3
chr6_+_29433247 1.25 ENSMUST00000101617.9
ENSMUST00000065090.8
filamin C, gamma
chr7_-_121620366 1.23 ENSMUST00000033160.15
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr15_-_76594723 1.23 ENSMUST00000036852.9
RecQ protein-like 4
chr6_-_4747157 1.22 ENSMUST00000126151.8
ENSMUST00000115577.9
ENSMUST00000101677.9
ENSMUST00000115579.8
ENSMUST00000004750.15
sarcoglycan, epsilon
chr5_-_108515740 1.22 ENSMUST00000197216.3
predicted gene 42517
chr8_+_34222058 1.21 ENSMUST00000167264.8
ENSMUST00000187392.7
general transcription factor II E, polypeptide 2 (beta subunit)
chr9_+_108673171 1.20 ENSMUST00000195514.6
ENSMUST00000085018.6
ENSMUST00000192028.6
inositol hexaphosphate kinase 2
chr6_+_85408953 1.17 ENSMUST00000045693.8
SET and MYND domain containing 5
chr4_-_133695264 1.17 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr18_+_82932747 1.15 ENSMUST00000071233.7
zinc finger protein 516
chr8_+_34221861 1.15 ENSMUST00000170705.8
general transcription factor II E, polypeptide 2 (beta subunit)
chr14_-_121616616 1.14 ENSMUST00000079817.8
serine/threonine kinase 24
chr4_-_152216322 1.14 ENSMUST00000105653.8
espin
chr11_-_116001037 1.13 ENSMUST00000106441.8
ENSMUST00000021120.6
tripartite motif-containing 47
chr10_-_45346297 1.12 ENSMUST00000079390.7
lin-28 homolog B (C. elegans)
chr7_-_126102470 1.11 ENSMUST00000206577.2
ataxin 2-like
chr5_-_34093678 1.11 ENSMUST00000030993.8
negative elongation factor complex member A, Whsc2
chr13_+_21938258 1.11 ENSMUST00000091709.3
H2B clustered histone 15
chr2_+_25070749 1.10 ENSMUST00000104999.4
Notch-regulated ankyrin repeat protein
chr5_-_137609634 1.10 ENSMUST00000054564.13
procollagen C-endopeptidase enhancer protein
chr2_+_180231038 1.10 ENSMUST00000029087.4
opioid growth factor receptor
chr8_+_34222266 1.08 ENSMUST00000190675.2
ENSMUST00000171010.8
general transcription factor II E, polypeptide 2 (beta subunit)
chrX_+_48559432 1.05 ENSMUST00000042444.7
Rho GTPase activating protein 36
chr19_+_5618096 1.04 ENSMUST00000096318.4
adaptor-related protein complex 5, beta 1 subunit
chr1_+_86514822 1.03 ENSMUST00000027446.11
COP9 signalosome subunit 7B
chr17_-_31877703 1.03 ENSMUST00000236475.2
ENSMUST00000166526.9
ENSMUST00000014684.6
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
chr6_+_85428464 1.02 ENSMUST00000032078.9
chaperonin containing Tcp1, subunit 7 (eta)
chr1_+_75358758 1.02 ENSMUST00000148515.8
ENSMUST00000113590.8
SPEG complex locus
chr12_-_69629758 1.02 ENSMUST00000058639.11
valosin containing protein lysine (K) methyltransferase
chr14_+_33645539 1.02 ENSMUST00000168727.3
growth differentiation factor 10
chr15_-_76594625 1.01 ENSMUST00000230544.2
RecQ protein-like 4
chr7_-_51655426 1.01 ENSMUST00000209193.2
small VCP/p97-interacting protein
chr8_-_81466126 1.01 ENSMUST00000043359.9
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr2_-_181101158 1.00 ENSMUST00000155535.2
ENSMUST00000029106.13
ENSMUST00000087409.10
zinc finger and BTB domain containing 46
chr1_-_74990821 1.00 ENSMUST00000164097.4
Indian hedgehog
chr8_+_110595216 0.99 ENSMUST00000179721.8
ENSMUST00000034175.5
PH domain and leucine rich repeat protein phosphatase 2
chr1_-_96799832 0.99 ENSMUST00000071985.6
solute carrier organic anion transporter family, member 4C1
chr11_-_96668318 0.97 ENSMUST00000127375.2
ENSMUST00000021246.9
ENSMUST00000107661.10
sorting nexin 11
chr5_-_137609691 0.97 ENSMUST00000031731.14
procollagen C-endopeptidase enhancer protein
chr9_-_119812042 0.97 ENSMUST00000214058.2
cysteine-serine-rich nuclear protein 1
chr1_-_52272370 0.97 ENSMUST00000114513.9
ENSMUST00000114510.8
glutaminase
chr9_-_44145309 0.97 ENSMUST00000206720.2
Casitas B-lineage lymphoma
chrX_+_55777139 0.96 ENSMUST00000023854.10
ENSMUST00000114769.9
four and a half LIM domains 1
chr2_+_78699360 0.96 ENSMUST00000028398.14
ubiquitin-conjugating enzyme E2E 3
chr14_+_54713557 0.95 ENSMUST00000164766.8
rad and gem related GTP binding protein 2
chr11_-_4696778 0.95 ENSMUST00000009219.3
calcium binding protein 7
chr17_+_24689366 0.95 ENSMUST00000053024.8
phosphoglycolate phosphatase
chr9_-_90152759 0.95 ENSMUST00000041767.14
ENSMUST00000128874.3
TBC1 domain family, member 2B
chr11_-_6015538 0.93 ENSMUST00000101585.10
ENSMUST00000066431.14
ENSMUST00000109815.9
ENSMUST00000109812.9
ENSMUST00000101586.3
ENSMUST00000093355.12
ENSMUST00000019133.11
calcium/calmodulin-dependent protein kinase II, beta
chr15_-_36283244 0.93 ENSMUST00000228358.2
ENSMUST00000022890.10
ring finger protein 19A
chr5_+_33978035 0.93 ENSMUST00000075812.11
ENSMUST00000114397.9
ENSMUST00000155880.8
nuclear receptor binding SET domain protein 2
chr5_+_145020640 0.92 ENSMUST00000031625.15
actin related protein 2/3 complex, subunit 1A
chr3_+_84859453 0.90 ENSMUST00000029727.8
F-box and WD-40 domain protein 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
2.3 7.0 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.0 5.9 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
1.9 7.6 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
1.7 8.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
1.2 5.0 GO:0010286 heat acclimation(GO:0010286)
1.2 9.7 GO:0032796 uropod organization(GO:0032796) early endosome to recycling endosome transport(GO:0061502)
1.1 6.8 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
1.1 6.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.9 2.8 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.9 3.7 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.7 26.9 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.7 7.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.7 4.8 GO:0015871 choline transport(GO:0015871)
0.6 2.5 GO:0006014 D-ribose metabolic process(GO:0006014)
0.6 7.3 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.6 6.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.6 1.8 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.6 6.1 GO:0008228 opsonization(GO:0008228)
0.5 4.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.5 1.9 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.5 2.3 GO:0070829 heterochromatin maintenance(GO:0070829)
0.5 5.0 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.4 2.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.4 3.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.4 1.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.4 2.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.4 2.5 GO:0002326 B cell lineage commitment(GO:0002326)
0.4 2.5 GO:0031133 regulation of axon diameter(GO:0031133)
0.4 2.7 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.4 1.1 GO:0072708 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.4 2.6 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 2.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.3 1.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.3 0.3 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.3 7.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.0 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.3 1.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 1.6 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.3 2.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.3 6.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 2.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.3 0.9 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
0.3 3.4 GO:0043320 natural killer cell degranulation(GO:0043320)
0.3 4.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.3 0.9 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.3 1.1 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.3 4.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 2.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.3 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.2 2.5 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 10.9 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.2 3.5 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.2 2.4 GO:0032532 regulation of microvillus length(GO:0032532)
0.2 5.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.2 7.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.2 0.7 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.2 0.9 GO:0003290 atrial septum secundum morphogenesis(GO:0003290)
0.2 3.9 GO:0006968 cellular defense response(GO:0006968)
0.2 1.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 9.0 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.2 1.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.6 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.2 0.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 1.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 0.9 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.4 GO:0048320 axial mesoderm formation(GO:0048320)
0.2 2.3 GO:0021873 forebrain neuroblast division(GO:0021873)
0.2 0.5 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
0.2 0.5 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 1.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.2 0.5 GO:1990869 beta selection(GO:0043366) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.2 1.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.0 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.6 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 2.7 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.4 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.1 4.9 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.1 1.8 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 2.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.5 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.2 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.6 GO:0036302 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) atrioventricular canal development(GO:0036302) mammary placode formation(GO:0060596)
0.1 5.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 3.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 1.5 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.1 0.2 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 7.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.9 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 1.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 3.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 1.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 1.8 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1 1.1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 1.0 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.5 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.5 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.1 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:1901873 regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.1 0.8 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 0.5 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.1 0.4 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.6 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 0.6 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.1 0.6 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.8 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 1.0 GO:1904867 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 4.3 GO:0006414 translational elongation(GO:0006414)
0.1 4.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.3 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.8 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 0.7 GO:2000232 regulation of rRNA processing(GO:2000232)
0.1 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 0.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 1.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.8 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.2 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.5 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.9 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 1.0 GO:0000338 protein deneddylation(GO:0000338)
0.1 1.9 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.6 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.1 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.9 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0043308 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.1 1.9 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 1.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.9 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 4.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.0 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.3 GO:0048840 otolith development(GO:0048840)
0.0 0.9 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 2.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 2.6 GO:0007129 synapsis(GO:0007129)
0.0 0.2 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 1.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 1.1 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.5 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.4 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.6 GO:1901020 negative regulation of calcium ion transmembrane transporter activity(GO:1901020)
0.0 1.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) regulation of neurotrophin production(GO:0032899) positive regulation of neurotrophin production(GO:0032901)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 1.7 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.0 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 1.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0045841 negative regulation of mitotic metaphase/anaphase transition(GO:0045841) mitotic spindle checkpoint(GO:0071174)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.4 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.8 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 1.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.4 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.6 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)
0.0 0.4 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.1 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 1.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.8 GO:0048747 muscle fiber development(GO:0048747)
0.0 1.0 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.3 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.1 GO:1900113 histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0033186 CAF-1 complex(GO:0033186)
1.7 7.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.2 10.0 GO:0008091 spectrin(GO:0008091)
1.1 3.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.0 6.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.9 6.5 GO:0005638 lamin filament(GO:0005638)
0.7 5.9 GO:0005577 fibrinogen complex(GO:0005577)
0.5 1.6 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.5 8.5 GO:0001939 female pronucleus(GO:0001939)
0.5 7.2 GO:0044327 dendritic spine head(GO:0044327)
0.4 10.8 GO:0032426 stereocilium tip(GO:0032426)
0.4 1.6 GO:0001740 Barr body(GO:0001740)
0.4 6.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.3 2.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 1.1 GO:0032021 NELF complex(GO:0032021)
0.3 1.8 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 0.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 1.8 GO:0070652 HAUS complex(GO:0070652)
0.2 1.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 1.3 GO:0071256 Sec61 translocon complex(GO:0005784) endoplasmic reticulum Sec complex(GO:0031205) translocon complex(GO:0071256)
0.2 5.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 0.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.2 1.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 0.5 GO:0002945 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.4 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 1.0 GO:0089701 U2AF(GO:0089701)
0.1 6.9 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.4 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.1 4.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 2.9 GO:0031143 pseudopodium(GO:0031143)
0.1 1.1 GO:0045298 tubulin complex(GO:0045298)
0.1 2.6 GO:0016600 flotillin complex(GO:0016600)
0.1 1.8 GO:0045120 pronucleus(GO:0045120)
0.1 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 5.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.7 GO:0001651 dense fibrillar component(GO:0001651)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 3.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.1 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.6 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 7.8 GO:0072562 blood microparticle(GO:0072562)
0.1 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 3.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 3.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 3.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.4 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 21.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 1.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 3.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 3.8 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 1.2 GO:0016528 sarcoplasm(GO:0016528)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.7 GO:0043197 dendritic spine(GO:0043197)
0.0 3.3 GO:0014069 postsynaptic density(GO:0014069)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0019959 interleukin-8 binding(GO:0019959)
1.7 8.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
1.5 5.9 GO:0070052 collagen V binding(GO:0070052)
1.3 4.0 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.0 4.2 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762)
1.0 3.0 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.8 6.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.8 4.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.6 7.0 GO:1903136 cuprous ion binding(GO:1903136)
0.6 1.8 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.6 6.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.5 1.5 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.5 7.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.5 9.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 2.1 GO:0097001 ceramide binding(GO:0097001)
0.4 3.7 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.4 2.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.4 2.2 GO:0032357 oxidized purine DNA binding(GO:0032357)
0.3 1.6 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.3 1.0 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.3 2.8 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 0.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 2.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 10.7 GO:0030506 ankyrin binding(GO:0030506)
0.2 0.7 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.2 1.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 1.3 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 2.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 1.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 0.8 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.2 5.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 0.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2 7.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 6.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 0.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 1.0 GO:0050733 RS domain binding(GO:0050733)
0.1 3.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.5 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 3.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 1.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.7 GO:0042134 rRNA primary transcript binding(GO:0042134) DNA topoisomerase binding(GO:0044547)
0.1 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.0 GO:0005113 patched binding(GO:0005113)
0.1 0.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 3.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.2 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.1 2.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.5 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 3.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.6 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.9 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.8 GO:0097157 pre-mRNA intronic binding(GO:0097157) mRNA CDS binding(GO:1990715)
0.1 5.3 GO:0030507 spectrin binding(GO:0030507)
0.1 1.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.5 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 2.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 7.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 1.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 11.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 1.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.9 GO:0043274 phospholipase binding(GO:0043274)
0.0 2.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.3 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 2.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 9.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.1 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 1.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 2.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 2.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 13.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 3.4 GO:0042393 histone binding(GO:0042393)
0.0 1.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 25.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 9.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 13.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 3.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 3.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 9.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 3.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 6.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 5.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.8 PID ATM PATHWAY ATM pathway
0.1 6.6 PID PLK1 PATHWAY PLK1 signaling events
0.1 5.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 6.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.3 PID MYC PATHWAY C-MYC pathway
0.1 5.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 2.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 1.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID P73PATHWAY p73 transcription factor network
0.0 0.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 31.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.5 8.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 7.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 6.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 6.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 6.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 6.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 3.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 1.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 8.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 3.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 4.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 7.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 6.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 4.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 6.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 7.9 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 3.9 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 1.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 5.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 3.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 3.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 5.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 3.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects