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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Foxo6

Z-value: 1.36

Motif logo

Transcription factors associated with Foxo6

Gene Symbol Gene ID Gene Info
ENSMUSG00000052135.9 Foxo6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxo6mm39_v1_chr4_-_120144546_1201445460.661.4e-05Click!

Activity profile of Foxo6 motif

Sorted Z-values of Foxo6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxo6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_87684299 13.87 ENSMUST00000020779.11
myeloperoxidase
chr16_-_36228798 12.80 ENSMUST00000023619.8
stefin A2
chr15_-_74983786 11.11 ENSMUST00000191451.2
ENSMUST00000100542.10
lymphocyte antigen 6 complex, locus C2
chr11_-_11977958 9.29 ENSMUST00000109654.8
growth factor receptor bound protein 10
chr9_+_98372575 8.05 ENSMUST00000035029.3
retinol binding protein 2, cellular
chr15_+_103362195 6.37 ENSMUST00000047405.9
NCK associated protein 1 like
chr2_+_118428690 4.54 ENSMUST00000038341.8
BUB1B, mitotic checkpoint serine/threonine kinase
chr6_-_41012435 3.96 ENSMUST00000031931.6
RIKEN cDNA 2210010C04 gene
chr4_+_134238310 3.89 ENSMUST00000105866.3
aurora kinase A and ninein interacting protein
chr5_+_110478558 3.34 ENSMUST00000112481.2
polymerase (DNA directed), epsilon
chr14_-_70945434 3.33 ENSMUST00000228346.2
exportin 7
chr2_-_25498459 3.14 ENSMUST00000058137.9
RAB, member RAS oncogene family-like 6
chr12_-_91351177 3.04 ENSMUST00000141429.8
centrosomal protein 128
chr5_-_117527094 3.04 ENSMUST00000111953.2
ENSMUST00000086461.13
replication factor C (activator 1) 5
chr19_+_8870362 2.98 ENSMUST00000096249.7
integrator complex subunit 5
chr18_-_32044877 2.95 ENSMUST00000054984.8
SFT2 domain containing 3
chr7_+_28140352 2.92 ENSMUST00000078845.13
glia maturation factor, gamma
chr2_+_129435115 2.91 ENSMUST00000099113.10
ENSMUST00000103202.10
signal-regulatory protein alpha
chr16_+_16964801 2.68 ENSMUST00000232479.2
ENSMUST00000232344.2
ENSMUST00000069064.7
YdjC homolog (bacterial)
chr3_+_84573499 2.63 ENSMUST00000107682.2
transmembrane protein 154
chr5_-_65548723 2.60 ENSMUST00000120094.5
ENSMUST00000127874.6
ENSMUST00000057885.13
ribosomal protein L9
chr2_+_91480513 2.42 ENSMUST00000090614.11
Rho GTPase activating protein 1
chr14_+_31888061 2.40 ENSMUST00000164341.2
nuclear receptor coactivator 4
chrX_+_133486391 2.31 ENSMUST00000113211.8
ribosomal protein L36A
chr2_+_129434738 2.13 ENSMUST00000153491.8
ENSMUST00000161620.8
ENSMUST00000179001.8
signal-regulatory protein alpha
chr7_+_28140450 2.09 ENSMUST00000135686.2
glia maturation factor, gamma
chr11_+_68986043 2.06 ENSMUST00000101004.9
period circadian clock 1
chr17_+_48653493 1.82 ENSMUST00000113237.4
triggering receptor expressed on myeloid cells 2
chr6_-_119925387 1.75 ENSMUST00000162541.8
WNK lysine deficient protein kinase 1
chrX_-_73325318 1.68 ENSMUST00000239458.2
ENSMUST00000019232.10
deoxyribonuclease 1-like 1
chr12_-_113802603 1.65 ENSMUST00000103458.3
ENSMUST00000193652.2
immunoglobulin heavy variable 5-16
chr2_+_163916042 1.60 ENSMUST00000018353.14
serine/threonine kinase 4
chr13_-_96803216 1.58 ENSMUST00000170287.8
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
chr2_-_92876398 1.55 ENSMUST00000111272.3
ENSMUST00000178666.8
ENSMUST00000147339.3
PR domain containing 11
chrX_-_73325204 1.55 ENSMUST00000114189.10
ENSMUST00000119361.4
deoxyribonuclease 1-like 1
chr15_+_75140241 1.53 ENSMUST00000023247.13
lymphocyte antigen 6 complex, locus F
chr15_+_52575796 1.52 ENSMUST00000037115.9
mediator complex subunit 30
chr17_-_33879224 1.51 ENSMUST00000130946.8
heterogeneous nuclear ribonucleoprotein M
chr6_+_57679621 1.46 ENSMUST00000050077.15
LanC (bacterial lantibiotic synthetase component C)-like 2
chr14_-_49482846 1.43 ENSMUST00000227113.2
ENSMUST00000130853.2
ENSMUST00000228936.2
ENSMUST00000022398.15
coiled-coil domain containing 198
chr15_-_74855264 1.40 ENSMUST00000023250.11
ENSMUST00000166694.2
lymphocyte antigen 6 complex, locus I
chr2_-_84255602 1.38 ENSMUST00000074262.9
calcitonin receptor-like
chr2_+_129434834 1.33 ENSMUST00000103203.8
signal-regulatory protein alpha
chr12_-_102390000 1.31 ENSMUST00000110020.8
legumain
chr1_+_171097891 1.21 ENSMUST00000064272.10
ENSMUST00000151863.8
ENSMUST00000141999.8
ENSMUST00000111313.10
ENSMUST00000126699.4
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3
chr6_+_122929410 1.15 ENSMUST00000117173.8
C-type lectin domain family 4, member a3
chr13_+_76727787 1.06 ENSMUST00000126960.8
ENSMUST00000109583.9
multiple C2 domains, transmembrane 1
chr4_-_136626073 1.06 ENSMUST00000046285.6
complement component 1, q subcomponent, alpha polypeptide
chr1_-_38704028 0.99 ENSMUST00000039827.14
AF4/FMR2 family, member 3
chr18_+_37884653 0.98 ENSMUST00000194928.2
protocadherin gamma subfamily B, 7
chr7_-_122969064 0.97 ENSMUST00000207010.2
ENSMUST00000167309.8
ENSMUST00000205262.2
ENSMUST00000106442.9
ENSMUST00000098060.5
Rho GTPase activating protein 17
chr6_+_57679455 0.97 ENSMUST00000072954.8
LanC (bacterial lantibiotic synthetase component C)-like 2
chr2_-_130928658 0.96 ENSMUST00000028794.10
ENSMUST00000110227.8
ENSMUST00000110226.2
sialic acid binding Ig-like lectin 1, sialoadhesin
chr17_+_25690538 0.94 ENSMUST00000234449.2
ENSMUST00000025002.3
ENSMUST00000235033.2
tektin 4
chr9_+_109865810 0.92 ENSMUST00000163190.8
microtubule-associated protein 4
chr9_-_21982637 0.92 ENSMUST00000179605.9
ENSMUST00000043922.7
zinc finger protein 653
chr19_-_17316906 0.91 ENSMUST00000169897.2
glucosaminyl (N-acetyl) transferase 1, core 2
chr7_+_28508220 0.89 ENSMUST00000172529.8
heterogeneous nuclear ribonucleoprotein L
chr10_+_39296005 0.86 ENSMUST00000157009.8
Fyn proto-oncogene
chr2_-_85966272 0.84 ENSMUST00000216566.3
ENSMUST00000214364.2
olfactory receptor 1039
chr16_+_51870001 0.82 ENSMUST00000227756.2
Casitas B-lineage lymphoma b
chr12_+_108376801 0.81 ENSMUST00000054955.14
echinoderm microtubule associated protein like 1
chrX_+_105964224 0.78 ENSMUST00000060576.8
lysophosphatidic acid receptor 4
chr6_-_129449739 0.77 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr3_+_103875574 0.75 ENSMUST00000063717.14
ENSMUST00000055425.15
ENSMUST00000123611.8
ENSMUST00000090685.11
putative homeodomain transcription factor 1
chr6_+_87405968 0.69 ENSMUST00000032125.7
bone morphogenetic protein 10
chr17_+_64203017 0.67 ENSMUST00000000129.14
fer (fms/fps related) protein kinase
chr4_-_62389098 0.67 ENSMUST00000135811.2
ENSMUST00000120095.8
ENSMUST00000030087.14
ENSMUST00000107452.8
ENSMUST00000155522.8
WD repeat domain 31
chr4_-_138858340 0.63 ENSMUST00000143971.2
mitochondrial contact site and cristae organizing system subunit 10
chr3_-_88455556 0.60 ENSMUST00000131775.2
ENSMUST00000008745.13
RAB25, member RAS oncogene family
chr12_+_108376884 0.58 ENSMUST00000109857.8
echinoderm microtubule associated protein like 1
chr13_+_76727799 0.54 ENSMUST00000109589.3
multiple C2 domains, transmembrane 1
chr4_+_108336164 0.51 ENSMUST00000155068.2
terminal uridylyl transferase 4
chr2_-_155199300 0.50 ENSMUST00000165234.2
ENSMUST00000077626.13
phosphatidylinositol glycan anchor biosynthesis, class U
chr11_-_59727752 0.48 ENSMUST00000156837.2
COP9 signalosome subunit 3
chr7_+_84502761 0.44 ENSMUST00000217039.3
ENSMUST00000211582.2
olfactory receptor 291
chr9_+_38340751 0.43 ENSMUST00000216502.3
ENSMUST00000216644.2
olfactory receptor 901
chr12_-_115832846 0.43 ENSMUST00000199373.2
immunoglobulin heavy variable 1-78
chr2_-_86061745 0.39 ENSMUST00000216056.2
olfactory receptor 1047
chr6_-_57821483 0.38 ENSMUST00000226191.2
vomeronasal 1 receptor 21
chr15_+_41573995 0.37 ENSMUST00000229769.2
oxidation resistance 1
chr6_+_42885812 0.35 ENSMUST00000216408.2
olfactory receptor 447
chr4_+_80752360 0.33 ENSMUST00000133655.8
ENSMUST00000006151.13
tyrosinase-related protein 1
chr17_-_23783063 0.33 ENSMUST00000095606.5
zinc finger protein 213
chr15_+_100052260 0.32 ENSMUST00000023768.14
disco interacting protein 2 homolog B
chr17_-_80885197 0.31 ENSMUST00000234602.2
cyclin-dependent kinase-like 4
chr8_+_26401698 0.31 ENSMUST00000120653.8
ENSMUST00000126226.2
potassium channel, subfamily U, member 1
chr1_-_65158717 0.31 ENSMUST00000144760.3
predicted gene 28845
chr8_+_71176713 0.30 ENSMUST00000034307.14
ENSMUST00000239435.2
ENSMUST00000239487.2
ENSMUST00000110095.3
phosphodiesterase 4C, cAMP specific
chr11_+_46126274 0.30 ENSMUST00000060185.3
fibronectin type III domain containing 9
chr14_+_51648277 0.29 ENSMUST00000159674.4
ENSMUST00000163019.9
ENSMUST00000233394.2
ENSMUST00000232951.2
ENSMUST00000232797.2
ENSMUST00000233766.2
ENSMUST00000233848.2
ENSMUST00000233280.2
ENSMUST00000233920.2
ENSMUST00000233126.2
ENSMUST00000233651.2
vomeronasal 2, receptor 88
chr10_+_23672842 0.24 ENSMUST00000119597.8
ENSMUST00000179321.8
ENSMUST00000133289.2
solute carrier family 18, subfamily B, member 1
chr18_-_60781365 0.24 ENSMUST00000143275.3
synaptopodin
chr7_-_102566717 0.19 ENSMUST00000214160.2
ENSMUST00000215773.2
olfactory receptor 571
chr2_+_36342599 0.17 ENSMUST00000072854.2
olfactory receptor 340
chr13_-_22375311 0.16 ENSMUST00000238109.2
vomeronasal 1 receptor 192
chr16_-_88360037 0.14 ENSMUST00000049697.5
claudin 8
chr11_+_87744033 0.13 ENSMUST00000038196.7
MKS transition zone complex subunit 1
chr18_-_12438695 0.13 ENSMUST00000122408.8
ENSMUST00000234183.2
ENSMUST00000142066.2
ENSMUST00000118525.9
ankyrin repeat domain 29
chr11_-_121563894 0.12 ENSMUST00000067399.14
ENSMUST00000062654.8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr5_+_88150390 0.12 ENSMUST00000189633.7
ENSMUST00000031211.6
submaxillary gland androgen regulated protein 3A
chrX_-_123045649 0.11 ENSMUST00000094491.5
vomeronasal 2, receptor 121
chr10_+_33913593 0.11 ENSMUST00000095758.3
trafficking protein particle complex 3 like
chr14_+_53478202 0.10 ENSMUST00000179583.3
T cell receptor alpha variable 12N-3
chr12_-_115019136 0.10 ENSMUST00000103519.2
ENSMUST00000192724.2
immunoglobulin heavy variable 1-49
chr11_+_29413734 0.10 ENSMUST00000155854.8
coiled coil domain containing 88A
chr3_+_103875261 0.09 ENSMUST00000117150.8
putative homeodomain transcription factor 1
chr4_+_43851565 0.08 ENSMUST00000107860.3
olfactory receptor 155
chr14_+_65842716 0.08 ENSMUST00000079469.7
nuclear GTPase, germinal center associated
chr4_+_62204678 0.07 ENSMUST00000084530.9
solute carrier family 31, member 2
chr1_+_179788675 0.07 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
CDC42 binding protein kinase alpha
chr17_-_31496301 0.06 ENSMUST00000235144.2
radial spoke head 1 homolog (Chlamydomonas)
chr4_-_156134922 0.05 ENSMUST00000184684.8
tubulin tyrosine ligase-like family, member 10
chr5_+_115417725 0.04 ENSMUST00000040421.11
coenzyme Q5 methyltransferase
chr2_-_111820618 0.02 ENSMUST00000216948.2
ENSMUST00000214935.2
ENSMUST00000217452.2
ENSMUST00000215045.2
olfactory receptor 1309
chr12_-_98225676 0.01 ENSMUST00000021390.9
galactosylceramidase
chr6_-_54949587 0.01 ENSMUST00000060655.15
nucleotide-binding oligomerization domain containing 1
chr10_+_129072073 0.00 ENSMUST00000203248.3
olfactory receptor 774
chr6_-_68784692 0.00 ENSMUST00000103334.4
immunoglobulin kappa chain variable 4-90
chr6_-_130044234 0.00 ENSMUST00000119096.2
killer cell lectin-like receptor, subfamily A, member 4
chr10_-_130333265 0.00 ENSMUST00000164227.4
vomeronasal 2, receptor 87

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.9 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
1.7 5.0 GO:0071846 actin filament debranching(GO:0071846)
1.6 6.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
1.1 3.3 GO:0045004 DNA replication proofreading(GO:0045004)
0.9 9.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.9 4.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.9 8.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.6 2.4 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.6 1.8 GO:0032499 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.4 1.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.4 2.4 GO:0032439 endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
0.4 1.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 1.7 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.3 1.4 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.3 2.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 3.0 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 0.9 GO:0080154 regulation of fertilization(GO:0080154)
0.1 1.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.1 3.0 GO:0016180 snRNA processing(GO:0016180)
0.1 2.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.3 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.1 0.9 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.7 GO:0038095 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Fc-epsilon receptor signaling pathway(GO:0038095) Kit signaling pathway(GO:0038109)
0.1 0.8 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 1.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.9 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.7 GO:1903242 regulation of cardiac muscle adaptation(GO:0010612) positive regulation of sarcomere organization(GO:0060298) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1 6.4 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.1 12.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.9 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 1.0 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 3.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.6 GO:0031268 pseudopodium organization(GO:0031268)
0.0 2.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.0 5.3 GO:0007051 spindle organization(GO:0007051)
0.0 0.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.5 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.4 GO:1902083 cellular response to hydroperoxide(GO:0071447) negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.8 GO:0006308 DNA catabolic process(GO:0006308)
0.0 1.5 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 1.0 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 1.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.9 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.7 3.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.5 3.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.4 6.4 GO:0031209 SCAR complex(GO:0031209)
0.3 2.4 GO:0097443 sorting endosome(GO:0097443)
0.3 4.5 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.2 3.0 GO:0032039 integrator complex(GO:0032039)
0.2 1.5 GO:0042382 paraspeckles(GO:0042382)
0.2 2.4 GO:0044754 autolysosome(GO:0044754)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 4.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 12.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 6.9 GO:0000922 spindle pole(GO:0000922)
0.0 0.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0097444 spine apparatus(GO:0097444)
0.0 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 3.3 GO:0005643 nuclear pore(GO:0005643)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.9 GO:0045120 pronucleus(GO:0045120)
0.0 2.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.5 1.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.4 8.0 GO:0019841 retinol binding(GO:0019841)
0.4 5.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 3.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 3.0 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 3.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 1.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.2 1.8 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 13.9 GO:0004601 peroxidase activity(GO:0004601)
0.2 0.9 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.9 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 16.5 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 1.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 12.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 2.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.5 GO:1990405 protein antigen binding(GO:1990405)
0.1 0.8 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.9 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 6.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 0.7 GO:0031433 telethonin binding(GO:0031433)
0.1 0.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 1.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 2.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 3.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.9 PID IL23 PATHWAY IL23-mediated signaling events
0.2 9.3 PID IGF1 PATHWAY IGF1 pathway
0.1 2.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.5 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.0 PID ATR PATHWAY ATR signaling pathway
0.1 8.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 3.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 6.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 6.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 9.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2 4.5 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 1.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 4.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 2.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 3.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 3.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)