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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Glis3

Z-value: 1.05

Motif logo

Transcription factors associated with Glis3

Gene Symbol Gene ID Gene Info
ENSMUSG00000052942.14 Glis3
ENSMUSG00000052942.14 Glis3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Glis3mm39_v1_chr19_-_28657477_28657523-0.554.9e-04Click!

Activity profile of Glis3 motif

Sorted Z-values of Glis3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Glis3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_+_55798517 4.03 ENSMUST00000117701.8
DDB1 and CUL4 associated factor 11
chr14_+_55798362 3.86 ENSMUST00000072530.11
ENSMUST00000128490.9
DDB1 and CUL4 associated factor 11
chr14_+_55797934 3.63 ENSMUST00000121622.8
ENSMUST00000143431.2
ENSMUST00000150481.8
DDB1 and CUL4 associated factor 11
chr4_+_144619397 3.16 ENSMUST00000105744.8
ENSMUST00000171001.8
dehydrogenase/reductase (SDR family) member 3
chr4_+_144619647 3.10 ENSMUST00000154208.8
dehydrogenase/reductase (SDR family) member 3
chr4_+_144619696 2.98 ENSMUST00000142808.8
dehydrogenase/reductase (SDR family) member 3
chr11_+_101358990 2.34 ENSMUST00000001347.7
Rho family GTPase 2
chr9_-_110571645 2.29 ENSMUST00000006005.12
parathyroid hormone 1 receptor
chr14_-_52151026 1.75 ENSMUST00000228164.2
N-myc downstream regulated gene 2
chr2_-_160714473 1.62 ENSMUST00000103111.9
zinc fingers and homeoboxes 3
chr13_+_120151982 1.42 ENSMUST00000179869.3
ENSMUST00000224188.2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr5_-_34345014 1.34 ENSMUST00000042701.13
ENSMUST00000119171.2
Max dimerization protein 4
chr9_-_108183356 1.33 ENSMUST00000192886.6
T cell leukemia translocation altered gene
chr11_+_57692399 1.31 ENSMUST00000020826.6
SAP30-like
chr6_+_17463748 1.27 ENSMUST00000115443.8
met proto-oncogene
chr13_-_63721412 1.19 ENSMUST00000195106.2
patched 1
chr2_-_29142965 1.18 ENSMUST00000155949.2
ENSMUST00000154682.8
ENSMUST00000028141.6
ENSMUST00000071201.5
RIKEN cDNA 6530402F18 gene
netrin G2
chr2_-_168583670 1.15 ENSMUST00000029060.11
ATPase, class II, type 9A
chr2_-_75534985 1.10 ENSMUST00000102672.5
nuclear factor, erythroid derived 2, like 2
chr2_-_168583817 1.08 ENSMUST00000109176.8
ENSMUST00000178504.8
ATPase, class II, type 9A
chr5_-_91550853 1.07 ENSMUST00000121044.6
betacellulin, epidermal growth factor family member
chr15_+_87428483 1.02 ENSMUST00000230414.2
TAFA chemokine like family member 5
chr2_-_160714904 1.01 ENSMUST00000109460.8
ENSMUST00000127201.2
zinc fingers and homeoboxes 3
chr13_+_58956495 1.01 ENSMUST00000225950.2
ENSMUST00000225583.2
neurotrophic tyrosine kinase, receptor, type 2
chr6_+_17463925 0.99 ENSMUST00000115442.8
met proto-oncogene
chr13_+_58956077 0.98 ENSMUST00000109838.10
neurotrophic tyrosine kinase, receptor, type 2
chr10_-_68114543 0.95 ENSMUST00000219238.2
AT rich interactive domain 5B (MRF1-like)
chr15_-_50753792 0.95 ENSMUST00000185183.2
transcriptional repressor GATA binding 1
chr2_-_168584020 0.93 ENSMUST00000109177.8
ATPase, class II, type 9A
chr2_-_160714749 0.92 ENSMUST00000176141.8
zinc fingers and homeoboxes 3
chr17_-_34250474 0.91 ENSMUST00000171872.3
ENSMUST00000025186.16
solute carrier family 39 (zinc transporter), member 7
chr9_-_108183162 0.91 ENSMUST00000044725.9
T cell leukemia translocation altered gene
chr7_+_46445512 0.89 ENSMUST00000006774.11
ENSMUST00000165031.8
general transcription factor II H, polypeptide 1
chr17_-_34250616 0.87 ENSMUST00000169397.9
solute carrier family 39 (zinc transporter), member 7
chr13_+_120151915 0.85 ENSMUST00000225543.2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr1_-_168259710 0.84 ENSMUST00000072863.6
pre B cell leukemia homeobox 1
chr11_-_72380730 0.84 ENSMUST00000045303.10
spinster homolog 2
chr1_-_168259264 0.81 ENSMUST00000176790.8
pre B cell leukemia homeobox 1
chr15_-_82783978 0.79 ENSMUST00000230403.2
transcription factor 20
chr6_+_17463819 0.79 ENSMUST00000140070.8
met proto-oncogene
chr2_-_73722932 0.78 ENSMUST00000154456.8
ENSMUST00000090802.11
ENSMUST00000055833.12
ENSMUST00000112007.8
ENSMUST00000112016.9
activating transcription factor 2
chr9_-_108183140 0.78 ENSMUST00000195615.2
T cell leukemia translocation altered gene
chr16_+_20492014 0.77 ENSMUST00000154950.8
ENSMUST00000115461.8
ENSMUST00000136713.5
eukaryotic translation initiation factor 4, gamma 1
chr7_+_45434755 0.77 ENSMUST00000233503.2
ENSMUST00000120005.10
ENSMUST00000211609.2
lemur tyrosine kinase 3
chr7_-_46445085 0.70 ENSMUST00000123725.2
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
chr3_+_52175757 0.70 ENSMUST00000053764.7
forkhead box O1
chr2_+_32536594 0.69 ENSMUST00000113272.8
ENSMUST00000009705.14
ENSMUST00000167841.8
endoglin
chr3_+_121220146 0.69 ENSMUST00000029773.13
calponin 3, acidic
chr7_-_46445305 0.67 ENSMUST00000107653.8
ENSMUST00000107654.8
ENSMUST00000014562.14
ENSMUST00000152759.8
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
chr9_+_21279802 0.65 ENSMUST00000214474.2
interleukin enhancer binding factor 3
chr7_-_49286594 0.65 ENSMUST00000032717.7
developing brain homeobox 1
chr11_+_98818640 0.64 ENSMUST00000107474.8
retinoic acid receptor, alpha
chr13_+_58955675 0.64 ENSMUST00000224402.2
neurotrophic tyrosine kinase, receptor, type 2
chr6_+_85164420 0.64 ENSMUST00000045942.9
empty spiracles homeobox 1
chr2_-_144173615 0.63 ENSMUST00000103171.10
ovo like zinc finger 2
chr12_+_102915709 0.63 ENSMUST00000179002.8
unc-79 homolog
chr15_+_102314578 0.63 ENSMUST00000170884.8
ENSMUST00000163709.8
trans-acting transcription factor 1
chr2_-_73722874 0.62 ENSMUST00000136958.8
ENSMUST00000112010.9
ENSMUST00000128531.8
ENSMUST00000112017.8
activating transcription factor 2
chrM_+_8603 0.60 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr11_-_115310743 0.59 ENSMUST00000106537.8
ENSMUST00000043931.9
ENSMUST00000073791.10
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D
chr17_-_23964807 0.59 ENSMUST00000046525.10
kringle containing transmembrane protein 2
chr1_-_160862364 0.58 ENSMUST00000177003.2
ENSMUST00000159250.9
ENSMUST00000162226.9
zinc finger and BTB domain containing 37
chr4_-_114991174 0.54 ENSMUST00000051400.8
cytochrome P450, family 4, subfamily x, polypeptide 1
chr1_-_168259465 0.54 ENSMUST00000176540.8
pre B cell leukemia homeobox 1
chr8_+_109441276 0.53 ENSMUST00000043896.10
zinc finger homeobox 3
chr9_-_20638233 0.52 ENSMUST00000217198.2
olfactomedin 2
chrX_-_37653396 0.51 ENSMUST00000016681.15
cullin 4B
chrX_+_104807868 0.51 ENSMUST00000033581.4
fibroblast growth factor 16
chr1_-_168259070 0.50 ENSMUST00000064438.11
pre B cell leukemia homeobox 1
chr7_+_126380655 0.50 ENSMUST00000172352.8
ENSMUST00000094037.5
T-box 6
chr7_-_78228116 0.49 ENSMUST00000206268.2
ENSMUST00000039431.14
neurotrophic tyrosine kinase, receptor, type 3
chr4_+_118285275 0.49 ENSMUST00000006557.13
ENSMUST00000167636.8
ENSMUST00000102673.11
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr15_+_102315579 0.46 ENSMUST00000169619.2
trans-acting transcription factor 1
chr16_-_50252703 0.46 ENSMUST00000066037.13
ENSMUST00000089399.11
ENSMUST00000089404.10
ENSMUST00000138166.8
bobby sox HMG box containing
chr10_+_63293284 0.46 ENSMUST00000105440.8
catenin (cadherin associated protein), alpha 3
chr13_+_119565424 0.46 ENSMUST00000026520.14
polyadenylate binding protein-interacting protein 1
chr11_+_115310963 0.46 ENSMUST00000106533.8
ENSMUST00000123345.2
potassium channel tetramerisation domain containing 2
chr1_+_166828982 0.46 ENSMUST00000165874.8
ENSMUST00000190081.7
family with sequence similarity 78, member B
chr8_+_106002772 0.46 ENSMUST00000014920.8
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr2_+_49509288 0.45 ENSMUST00000028102.14
kinesin family member 5C
chr5_-_8417982 0.45 ENSMUST00000088761.11
ENSMUST00000115386.8
ENSMUST00000050166.14
ENSMUST00000046838.14
ENSMUST00000115388.9
ENSMUST00000088744.12
ENSMUST00000115385.2
a disintegrin and metallopeptidase domain 22
chr4_+_85972125 0.44 ENSMUST00000107178.9
ENSMUST00000048885.12
ENSMUST00000141889.8
ENSMUST00000120678.2
ADAMTS-like 1
chr14_-_62530408 0.43 ENSMUST00000063169.10
deleted in lymphocytic leukemia, 7
chr7_+_27290969 0.43 ENSMUST00000108344.9
thymoma viral proto-oncogene 2
chr1_+_166829001 0.42 ENSMUST00000126198.3
family with sequence similarity 78, member B
chr6_-_28134544 0.42 ENSMUST00000115323.8
glutamate receptor, metabotropic 8
chr11_+_115310885 0.41 ENSMUST00000103035.10
potassium channel tetramerisation domain containing 2
chr11_-_69692542 0.40 ENSMUST00000011285.11
ENSMUST00000102585.2
fibroblast growth factor 11
chr11_-_70128587 0.40 ENSMUST00000108576.10
RIKEN cDNA 0610010K14 gene
chr7_+_27291126 0.39 ENSMUST00000167435.8
thymoma viral proto-oncogene 2
chrX_-_93166693 0.39 ENSMUST00000113925.8
zinc finger protein X-linked
chr11_-_88608958 0.39 ENSMUST00000107908.2
musashi RNA-binding protein 2
chr3_+_68401536 0.38 ENSMUST00000182719.8
schwannomin interacting protein 1
chr17_-_81035453 0.36 ENSMUST00000234133.2
ENSMUST00000112389.9
ENSMUST00000025089.9
mitogen-activated protein kinase kinase kinase kinase 3
chr15_-_83609127 0.36 ENSMUST00000171496.9
ENSMUST00000043634.12
ENSMUST00000076060.12
ENSMUST00000016907.8
signal peptide, CUB domain, EGF-like 1
chr9_+_54672032 0.36 ENSMUST00000034830.9
cellular retinoic acid binding protein I
chr1_-_22031718 0.35 ENSMUST00000029667.13
ENSMUST00000173058.8
ENSMUST00000173404.2
potassium voltage-gated channel, subfamily Q, member 5
chr4_-_120604445 0.35 ENSMUST00000030376.8
potassium voltage-gated channel, subfamily Q, member 4
chr9_-_48747474 0.35 ENSMUST00000216150.2
zinc finger and BTB domain containing 16
chr6_+_99669640 0.34 ENSMUST00000101122.3
G protein-coupled receptor 27
chr2_+_74566740 0.34 ENSMUST00000111982.8
homeobox D3
chr1_-_84816379 0.34 ENSMUST00000187818.2
thyroid hormone receptor interactor 12
chr6_+_108637577 0.33 ENSMUST00000032194.11
basic helix-loop-helix family, member e40
chr7_-_109271171 0.33 ENSMUST00000208734.2
DENN domain containing 2B
chrX_+_7439839 0.33 ENSMUST00000144719.9
ENSMUST00000234896.2
Foxp3 regulating long intergenic noncoding RNA
forkhead box P3
chr7_+_141276575 0.32 ENSMUST00000185406.8
mucin 2
chr6_-_83549399 0.32 ENSMUST00000206592.2
ENSMUST00000206400.2
STAM binding protein
chr15_-_97902576 0.32 ENSMUST00000023123.15
collagen, type II, alpha 1
chr19_-_46314945 0.31 ENSMUST00000225781.2
ENSMUST00000223903.2
pleckstrin and Sec7 domain containing
chr9_-_48747232 0.30 ENSMUST00000093852.5
zinc finger and BTB domain containing 16
chr13_+_48414582 0.29 ENSMUST00000021810.3
inhibitor of DNA binding 4
chr11_-_51891259 0.29 ENSMUST00000020657.13
ubiquitin-conjugating enzyme E2B
chr13_+_119565669 0.29 ENSMUST00000173627.8
ENSMUST00000126957.9
ENSMUST00000174691.8
polyadenylate binding protein-interacting protein 1
chr5_-_29683468 0.29 ENSMUST00000165512.4
ENSMUST00000001608.8
motor neuron and pancreas homeobox 1
chrX_-_103244728 0.27 ENSMUST00000056502.7
neurite extension and migration factor
chr13_+_83720484 0.27 ENSMUST00000196207.5
myocyte enhancer factor 2C
chr11_+_115921129 0.27 ENSMUST00000021116.12
ENSMUST00000106452.2
unkempt family zinc finger
chr15_-_97902515 0.26 ENSMUST00000088355.12
collagen, type II, alpha 1
chr3_+_89153258 0.26 ENSMUST00000040888.12
keratinocyte associated protein 2
chr10_+_61010983 0.25 ENSMUST00000143207.8
ENSMUST00000148181.8
ENSMUST00000151886.8
thymus, brain and testes associated
chr18_-_78249612 0.25 ENSMUST00000163367.3
solute carrier family 14 (urea transporter), member 2
chr4_+_119112590 0.25 ENSMUST00000084309.12
claudin 19
chr4_-_114991478 0.25 ENSMUST00000106545.8
cytochrome P450, family 4, subfamily x, polypeptide 1
chr15_-_75760602 0.25 ENSMUST00000184858.2
maestro heat-like repeat family member 6
chr3_-_94490023 0.24 ENSMUST00000029783.16
sorting nexin family member 27
chr4_+_119112692 0.24 ENSMUST00000094823.4
claudin 19
chr13_+_119565118 0.23 ENSMUST00000109203.9
polyadenylate binding protein-interacting protein 1
chrX_-_133909934 0.23 ENSMUST00000113185.9
ENSMUST00000064659.6
zinc finger, matrin type 1
chr15_-_50753437 0.23 ENSMUST00000077935.6
transcriptional repressor GATA binding 1
chr3_-_89153135 0.22 ENSMUST00000041022.15
tripartite motif-containing 46
chr11_+_98686617 0.22 ENSMUST00000107485.8
ENSMUST00000107487.10
male specific lethal 1
chr10_-_62723103 0.22 ENSMUST00000218438.2
tet methylcytosine dioxygenase 1
chrX_-_110606766 0.21 ENSMUST00000113422.9
ENSMUST00000038472.7
highly divergent homeobox
chr7_+_5023375 0.21 ENSMUST00000076251.7
zinc finger protein 865
chr8_-_88686188 0.21 ENSMUST00000109655.9
zinc finger protein 423
chrX_-_93166964 0.21 ENSMUST00000137853.8
zinc finger protein X-linked
chr17_-_25652750 0.20 ENSMUST00000159610.8
ENSMUST00000159048.8
ENSMUST00000078496.12
calcium channel, voltage-dependent, T type, alpha 1H subunit
chrX_-_154406321 0.20 ENSMUST00000038665.6
patched domain containing 1
chr2_-_152793376 0.20 ENSMUST00000123121.9
dual specificity phosphatase-like 15
chr13_+_38009951 0.20 ENSMUST00000138043.8
ras responsive element binding protein 1
chr13_-_30168374 0.19 ENSMUST00000221536.2
ENSMUST00000222730.2
E2F transcription factor 3
chr11_-_106240215 0.19 ENSMUST00000021056.8
sodium channel, voltage-gated, type IV, alpha
chr18_-_47501513 0.19 ENSMUST00000076043.13
ENSMUST00000135790.8
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr13_+_83720457 0.18 ENSMUST00000196730.5
myocyte enhancer factor 2C
chr2_-_144174066 0.18 ENSMUST00000037423.4
ovo like zinc finger 2
chr15_+_89383799 0.17 ENSMUST00000109309.9
SH3 and multiple ankyrin repeat domains 3
chr19_-_47303184 0.17 ENSMUST00000237796.2
SH3 and PX domains 2A
chr5_-_134485081 0.16 ENSMUST00000111244.5
general transcription factor II I repeat domain-containing 1
chr2_-_152793469 0.16 ENSMUST00000037715.7
dual specificity phosphatase-like 15
chr7_+_18659787 0.16 ENSMUST00000032571.10
ENSMUST00000220302.2
NOVA alternative splicing regulator 2
chr15_+_89384317 0.15 ENSMUST00000135214.2
SH3 and multiple ankyrin repeat domains 3
chr2_-_122199604 0.15 ENSMUST00000151130.8
Src homology 2 domain containing F
chr15_-_103248512 0.15 ENSMUST00000168828.3
zinc finger protein 385A
chr3_-_142587678 0.15 ENSMUST00000043812.15
protein kinase N2
chr17_-_24866749 0.14 ENSMUST00000234121.2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr7_-_142453722 0.14 ENSMUST00000000219.10
tyrosine hydroxylase
chr6_-_52222776 0.13 ENSMUST00000048026.10
homeobox A11
chr9_-_50663648 0.12 ENSMUST00000217159.2
heat shock protein 2
chr11_-_70128462 0.12 ENSMUST00000100950.10
RIKEN cDNA 0610010K14 gene
chr11_+_105072353 0.12 ENSMUST00000106941.9
tousled-like kinase 2 (Arabidopsis)
chr1_-_168259839 0.11 ENSMUST00000188912.7
pre B cell leukemia homeobox 1
chr14_+_53257873 0.11 ENSMUST00000196756.2
T cell receptor alpha variable 7D-6
chr7_+_3381434 0.11 ENSMUST00000092891.6
calcium channel, voltage-dependent, gamma subunit 7
chr2_-_152793607 0.11 ENSMUST00000109811.4
dual specificity phosphatase-like 15
chr15_+_102314809 0.10 ENSMUST00000001326.7
trans-acting transcription factor 1
chrX_+_98864627 0.10 ENSMUST00000096363.3
transmembrane protein 28
chr11_-_33097400 0.10 ENSMUST00000020507.8
fibroblast growth factor 18
chr17_+_35191661 0.10 ENSMUST00000007248.5
heat shock protein 1-like
chr4_-_148215135 0.09 ENSMUST00000030862.5
dorsal inhibitory axon guidance protein
chr1_-_74323795 0.09 ENSMUST00000178235.8
ENSMUST00000006462.14
angio-associated migratory protein
chr2_-_122199643 0.08 ENSMUST00000125826.8
Src homology 2 domain containing F
chr11_+_96162283 0.08 ENSMUST00000000010.9
ENSMUST00000174042.3
homeobox B9
chr9_+_107805647 0.08 ENSMUST00000085073.2
actin-like 11
chr18_-_47501897 0.07 ENSMUST00000019791.14
ENSMUST00000115449.9
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr9_+_106247943 0.06 ENSMUST00000173748.2
dual specificity phosphatase 7
chr19_+_41471395 0.06 ENSMUST00000237208.2
ENSMUST00000238398.2
ligand dependent nuclear receptor corepressor
chr17_-_85097945 0.05 ENSMUST00000112308.9
leucine-rich PPR-motif containing
chr9_+_31191820 0.05 ENSMUST00000117389.8
ENSMUST00000215499.2
PR domain containing 10
chr16_+_22713593 0.05 ENSMUST00000232674.2
alpha-2-HS-glycoprotein
chr10_-_43934774 0.04 ENSMUST00000239010.2
crystallin beta-gamma domain containing 1
chr1_-_74323536 0.04 ENSMUST00000190008.2
angio-associated migratory protein
chr6_+_108637816 0.04 ENSMUST00000163617.2
basic helix-loop-helix family, member e40
chr13_-_40883893 0.04 ENSMUST00000021787.7
transcription factor AP-2, alpha
chr9_+_50663171 0.03 ENSMUST00000214609.2
crystallin, alpha B
chr9_-_50663571 0.03 ENSMUST00000042790.5
heat shock protein 2
chr8_+_70953766 0.03 ENSMUST00000127983.2
cytokine receptor-like factor 1
chr15_-_94302139 0.01 ENSMUST00000035342.11
ENSMUST00000155907.2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
chr2_-_119308094 0.01 ENSMUST00000110808.2
ENSMUST00000049920.14
INO80 complex subunit
chr16_+_20492267 0.01 ENSMUST00000115460.8
eukaryotic translation initiation factor 4, gamma 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.4 3.0 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.4 9.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 1.2 GO:1904828 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.4 1.1 GO:1904753 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.4 1.4 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.3 1.8 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2 3.2 GO:0072675 osteoclast fusion(GO:0072675)
0.2 1.2 GO:0010157 response to chlorate(GO:0010157)
0.2 0.7 GO:0003032 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.2 0.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 0.5 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 0.8 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 2.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 2.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.5 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.5 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.8 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.4 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.5 GO:0098961 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 0.3 GO:0002660 positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.8 GO:0060214 endocardium formation(GO:0060214)
0.1 0.4 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.4 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.1 2.8 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.6 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 1.1 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 0.3 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 1.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 2.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 3.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.5 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.6 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.6 GO:0060174 limb bud formation(GO:0060174)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.9 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.7 GO:0071455 response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455)
0.0 0.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.6 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 1.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.6 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0034651 cortisol biosynthetic process(GO:0034651)
0.0 0.1 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 1.9 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0033128 positive regulation of reciprocal meiotic recombination(GO:0010845) negative regulation of histone phosphorylation(GO:0033128)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 1.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.3 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.4 GO:0060746 parental behavior(GO:0060746)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.5 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 1.4 GO:0043473 pigmentation(GO:0043473)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0031084 BLOC-2 complex(GO:0031084)
0.3 12.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.9 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.2 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 3.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 4.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.3 GO:0031526 brush border membrane(GO:0031526)
0.0 3.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 2.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.8 3.0 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.8 2.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.4 2.6 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.3 2.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.2 1.2 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.8 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 3.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.0 GO:0008494 translation activator activity(GO:0008494)
0.1 0.7 GO:0005534 galactose binding(GO:0005534)
0.1 0.5 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.5 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 1.3 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.4 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 1.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.8 GO:0070330 aromatase activity(GO:0070330)
0.0 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 2.3 GO:0047485 protein N-terminus binding(GO:0047485)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 3.1 PID SHP2 PATHWAY SHP2 signaling
0.0 0.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.7 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels