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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Gmeb2

Z-value: 1.24

Motif logo

Transcription factors associated with Gmeb2

Gene Symbol Gene ID Gene Info
ENSMUSG00000038705.14 Gmeb2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gmeb2mm39_v1_chr2_-_180928867_1809288670.651.7e-05Click!

Activity profile of Gmeb2 motif

Sorted Z-values of Gmeb2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Gmeb2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_32427789 7.22 ENSMUST00000120680.2
transferrin receptor
chr11_-_101979297 5.53 ENSMUST00000017458.11
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr7_+_79309938 5.44 ENSMUST00000035977.9
TOPBP1-interacting checkpoint and replication regulator
chr15_-_99549457 5.32 ENSMUST00000171908.2
ENSMUST00000171702.8
ENSMUST00000109581.3
ENSMUST00000169810.8
ENSMUST00000023756.12
Rac GTPase-activating protein 1
chr11_+_78192355 5.06 ENSMUST00000045026.4
sperm associated antigen 5
chr11_-_40624200 4.66 ENSMUST00000020579.9
hyaluronan mediated motility receptor (RHAMM)
chr6_-_70769135 4.37 ENSMUST00000066134.6
ribose 5-phosphate isomerase A
chr10_+_58282735 4.24 ENSMUST00000003310.7
RAN binding protein 2
chr5_+_143534455 3.93 ENSMUST00000169329.8
ENSMUST00000067145.12
ENSMUST00000119488.2
ENSMUST00000118121.2
ENSMUST00000200267.2
ENSMUST00000196487.2
family with sequence similarity 220, member A
family with sequence similarity 220, member A
chr12_-_110945415 3.91 ENSMUST00000135131.2
ENSMUST00000043459.13
ENSMUST00000128353.8
ankyrin repeat domain 9
chr15_-_79430742 3.85 ENSMUST00000231053.2
ENSMUST00000229431.2
DEAD box helicase 17
chr2_+_75489596 3.43 ENSMUST00000111964.8
ENSMUST00000111962.8
ENSMUST00000111961.8
ENSMUST00000164947.9
ENSMUST00000090792.11
heterogeneous nuclear ribonucleoprotein A3
chr13_-_49806231 3.13 ENSMUST00000021818.9
centromere protein P
chr1_-_55066629 3.10 ENSMUST00000027127.14
splicing factor 3b, subunit 1
chr7_-_83533497 2.99 ENSMUST00000094216.5
talin rod domain containing 1
chr15_+_81900570 2.97 ENSMUST00000069530.13
ENSMUST00000168581.8
ENSMUST00000164779.2
X-ray repair complementing defective repair in Chinese hamster cells 6
chr1_-_162567919 2.95 ENSMUST00000182331.2
ENSMUST00000183011.8
ENSMUST00000182593.8
ENSMUST00000182149.8
proline-rich coiled-coil 2C
chr11_+_116089678 2.87 ENSMUST00000021130.7
TEN1 telomerase capping complex subunit
chr11_-_85030761 2.86 ENSMUST00000108075.9
ubiquitin specific peptidase 32
chr1_-_162568108 2.77 ENSMUST00000028016.16
ENSMUST00000182660.8
proline-rich coiled-coil 2C
chr12_-_110945052 2.69 ENSMUST00000140788.8
ankyrin repeat domain 9
chr9_-_64080161 2.60 ENSMUST00000176299.8
ENSMUST00000130127.8
ENSMUST00000176794.8
ENSMUST00000177045.8
zwilch kinetochore protein
chr12_-_110945376 2.42 ENSMUST00000142012.2
ankyrin repeat domain 9
chr8_-_124675939 2.40 ENSMUST00000044795.8
nucleoporin 133
chr12_+_17398421 2.33 ENSMUST00000046011.12
nucleolar protein 10
chr6_-_112673565 2.31 ENSMUST00000113182.8
ENSMUST00000113180.8
ENSMUST00000068487.12
ENSMUST00000077088.11
RAD18 E3 ubiquitin protein ligase
chr15_-_36283244 2.25 ENSMUST00000228358.2
ENSMUST00000022890.10
ring finger protein 19A
chr6_-_51446752 2.19 ENSMUST00000204188.3
ENSMUST00000203220.3
ENSMUST00000114459.8
ENSMUST00000090002.10
heterogeneous nuclear ribonucleoprotein A2/B1
chr7_-_110682204 2.18 ENSMUST00000161051.8
ENSMUST00000160132.8
ENSMUST00000162415.9
eukaryotic translation initiation factor 4, gamma 2
chr1_+_175708341 2.14 ENSMUST00000195196.6
ENSMUST00000194306.6
ENSMUST00000193822.6
exonuclease 1
chr2_-_163486998 2.13 ENSMUST00000017851.4
serine incorporator 3
chr14_-_30741012 2.11 ENSMUST00000037739.8
guanine nucleotide binding protein-like 3 (nucleolar)
chr9_+_56325893 2.04 ENSMUST00000034879.5
ENSMUST00000215269.2
high mobility group 20A
chrX_+_133501928 2.03 ENSMUST00000074950.11
ENSMUST00000113203.2
ENSMUST00000113202.8
ENSMUST00000050331.13
ENSMUST00000059297.6
heterogeneous nuclear ribonucleoprotein H2
chr5_+_146769915 2.00 ENSMUST00000075453.9
ENSMUST00000099272.3
ribosomal protein L21
chr19_+_8944369 1.98 ENSMUST00000052248.8
eukaryotic translation elongation factor 1 gamma
chr2_-_53081199 1.95 ENSMUST00000239398.2
ENSMUST00000076313.14
ENSMUST00000210789.3
pre-mRNA processing factor 40A
chr5_+_86952072 1.93 ENSMUST00000119339.8
ENSMUST00000120498.8
YTH domain containing 1
chr5_+_146769700 1.91 ENSMUST00000035983.12
ribosomal protein L21
chr11_+_95715295 1.90 ENSMUST00000150134.2
ENSMUST00000054173.4
phosphatase, orphan 1
chr1_+_150268544 1.87 ENSMUST00000124973.9
translocated promoter region, nuclear basket protein
chr6_-_51446850 1.83 ENSMUST00000069949.13
heterogeneous nuclear ribonucleoprotein A2/B1
chr14_-_30740946 1.79 ENSMUST00000228341.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr13_+_81805782 1.78 ENSMUST00000224300.2
ENSMUST00000224592.2
LysM, putative peptidoglycan-binding, domain containing 3
chr10_-_80269436 1.76 ENSMUST00000105346.10
ENSMUST00000020377.13
ENSMUST00000105340.8
ENSMUST00000020379.13
ENSMUST00000105344.8
ENSMUST00000105342.8
ENSMUST00000105345.10
ENSMUST00000105343.8
transcription factor 3
chr11_+_98700613 1.75 ENSMUST00000169695.2
cancer susceptibility candidate 3
chr9_+_64080644 1.69 ENSMUST00000034966.9
ribosomal protein L4
chr12_+_33479604 1.68 ENSMUST00000020877.9
RNA polymerase I subunit F
chr3_-_130523954 1.68 ENSMUST00000196202.5
ENSMUST00000133802.6
ENSMUST00000062601.14
ENSMUST00000200517.2
ribosomal protein L34
chr9_+_64718708 1.67 ENSMUST00000213926.2
DENN/MADD domain containing 4A
chr16_-_90841360 1.67 ENSMUST00000118522.8
PAX3 and PAX7 binding protein 1
chr1_-_52272370 1.62 ENSMUST00000114513.9
ENSMUST00000114510.8
glutaminase
chr2_-_37593856 1.55 ENSMUST00000155237.2
spermatid perinuclear RNA binding protein
chr9_+_109961079 1.51 ENSMUST00000197480.5
ENSMUST00000197984.5
ENSMUST00000199896.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr13_+_81805941 1.50 ENSMUST00000049055.8
LysM, putative peptidoglycan-binding, domain containing 3
chr12_-_70033732 1.45 ENSMUST00000021467.8
salvador family WW domain containing 1
chr14_+_30741082 1.45 ENSMUST00000112098.11
ENSMUST00000112095.8
ENSMUST00000112106.8
ENSMUST00000146325.8
polybromo 1
chr6_+_51447317 1.44 ENSMUST00000094623.10
chromobox 3
chr4_-_109333866 1.42 ENSMUST00000030284.10
ring finger protein 11
chr15_-_58695379 1.36 ENSMUST00000072113.6
transmembrane protein 65
chr7_+_4140031 1.32 ENSMUST00000128756.8
ENSMUST00000132086.8
ENSMUST00000037472.13
ENSMUST00000117274.8
ENSMUST00000121270.8
ENSMUST00000144248.3
leukocyte receptor cluster (LRC) member 8
chrX_+_7708034 1.28 ENSMUST00000033494.16
ENSMUST00000115666.8
OTU domain containing 5
chr10_-_120037464 1.27 ENSMUST00000020448.11
interleukin-1 receptor-associated kinase 3
chr9_-_59393893 1.23 ENSMUST00000171975.8
ariadne RBR E3 ubiquitin protein ligase 1
chr4_+_108857803 1.18 ENSMUST00000065977.11
ENSMUST00000102736.9
nardilysin, N-arginine dibasic convertase, NRD convertase 1
chr13_-_100787481 1.17 ENSMUST00000177848.3
ENSMUST00000022136.14
RAD17 checkpoint clamp loader component
chr11_-_97673203 1.17 ENSMUST00000128801.2
ENSMUST00000103146.5
ribosomal protein L23
chr9_-_107166543 1.13 ENSMUST00000192054.2
mitogen-activated protein kinase-activated protein kinase 3
chr11_+_117006020 1.12 ENSMUST00000103026.10
ENSMUST00000090433.6
SEC14-like lipid binding 1
chr11_-_107238956 1.10 ENSMUST00000134763.2
phosphatidylinositol transfer protein, cytoplasmic 1
chr12_+_31704853 1.10 ENSMUST00000036862.5
component of oligomeric golgi complex 5
chr13_-_96807326 1.09 ENSMUST00000169196.8
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
chr4_-_109522502 1.08 ENSMUST00000063531.5
cyclin dependent kinase inhibitor 2C
chr11_+_94827050 1.05 ENSMUST00000001547.8
collagen, type I, alpha 1
chr13_-_17979675 1.05 ENSMUST00000223490.2
cyclin-dependent kinase 13
chr9_-_123546642 1.04 ENSMUST00000165754.8
ENSMUST00000026274.14
leucine zipper transcription factor-like 1
chr16_-_91443794 1.03 ENSMUST00000232367.2
ENSMUST00000231380.2
ENSMUST00000231444.2
ENSMUST00000232289.2
ENSMUST00000120450.2
ENSMUST00000023684.14
phosphoribosylglycinamide formyltransferase
chrX_-_156275231 1.03 ENSMUST00000112529.8
spermine synthase
chrX_+_7656225 0.99 ENSMUST00000136930.8
ENSMUST00000115675.9
ENSMUST00000101694.10
GRIP1 associated protein 1
chr14_-_36857202 0.97 ENSMUST00000165649.4
ENSMUST00000224769.2
growth hormone inducible transmembrane protein
chr11_+_23615612 0.97 ENSMUST00000109525.8
ENSMUST00000020520.11
pseudouridylate synthase 10
chr9_+_56326089 0.96 ENSMUST00000213242.2
ENSMUST00000214771.2
ENSMUST00000217518.2
ENSMUST00000214869.2
high mobility group 20A
chr11_-_93776580 0.95 ENSMUST00000066888.10
UTP18 small subunit processome component
chr11_-_118181044 0.95 ENSMUST00000106296.9
ENSMUST00000092382.10
ubiquitin specific peptidase 36
chr15_-_79430942 0.92 ENSMUST00000054014.9
ENSMUST00000229877.2
DEAD box helicase 17
chr14_-_36857083 0.91 ENSMUST00000042564.17
growth hormone inducible transmembrane protein
chr3_-_95125002 0.84 ENSMUST00000107209.8
GA repeat binding protein, beta 2
chr2_+_53082079 0.81 ENSMUST00000028336.7
ADP-ribosylation factor-like 6 interacting protein 6
chr1_+_150269001 0.80 ENSMUST00000119161.9
translocated promoter region, nuclear basket protein
chrX_+_7656251 0.79 ENSMUST00000140540.2
GRIP1 associated protein 1
chr11_+_40624466 0.79 ENSMUST00000020578.11
NudC domain containing 2
chr8_-_123768759 0.77 ENSMUST00000098334.13
ankyrin repeat domain 11
chr16_-_55659194 0.77 ENSMUST00000096026.9
ENSMUST00000036273.13
ENSMUST00000114457.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr9_-_123546605 0.76 ENSMUST00000163207.2
leucine zipper transcription factor-like 1
chr7_-_55612172 0.76 ENSMUST00000126604.8
ENSMUST00000117812.8
ENSMUST00000119201.8
non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)
chr1_-_91386976 0.73 ENSMUST00000069620.10
period circadian clock 2
chr3_-_95189387 0.71 ENSMUST00000015855.8
prune exopolyphosphatase
chr13_-_96807346 0.68 ENSMUST00000022176.15
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
chr7_-_55612213 0.67 ENSMUST00000032635.14
ENSMUST00000152649.8
non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)
chr3_-_95125190 0.66 ENSMUST00000136139.8
GA repeat binding protein, beta 2
chr6_+_21949570 0.66 ENSMUST00000031680.10
ENSMUST00000115389.8
ENSMUST00000151473.8
inhibitor of growth family, member 3
chr11_-_118180895 0.65 ENSMUST00000144153.8
ubiquitin specific peptidase 36
chrX_-_149371067 0.65 ENSMUST00000140207.8
ENSMUST00000112719.2
ENSMUST00000112727.10
ENSMUST00000112721.10
ENSMUST00000026303.16
apurinic/apyrimidinic endonuclease 2
chr12_-_56392646 0.64 ENSMUST00000021416.9
MAP3K12 binding inhibitory protein 1
chrX_+_7708295 0.63 ENSMUST00000115667.10
ENSMUST00000115668.10
ENSMUST00000115665.2
OTU domain containing 5
chr1_+_166206666 0.63 ENSMUST00000027846.8
transcriptional adaptor 1
chr11_+_68986043 0.63 ENSMUST00000101004.9
period circadian clock 1
chr4_+_101276474 0.62 ENSMUST00000102780.8
ENSMUST00000106946.8
ENSMUST00000106945.8
adenylate kinase 4
chr12_-_31704766 0.62 ENSMUST00000020977.4
dihydrouridine synthase 4-like (S. cerevisiae)
chr4_+_44756553 0.62 ENSMUST00000107824.9
zinc finger, CCHC domain containing 7
chr11_+_83193495 0.59 ENSMUST00000176430.8
ENSMUST00000065692.14
ENSMUST00000142680.2
adaptor-related protein complex 2, beta 1 subunit
chr11_+_93776650 0.57 ENSMUST00000107853.8
ENSMUST00000107850.8
mbt domain containing 1
chr7_-_119319965 0.57 ENSMUST00000033236.9
THUMP domain containing 1
chr11_+_93776965 0.57 ENSMUST00000063718.11
ENSMUST00000107854.9
mbt domain containing 1
chr14_-_52341426 0.57 ENSMUST00000227536.2
ENSMUST00000227195.2
ENSMUST00000228815.2
ENSMUST00000228198.2
ENSMUST00000227458.2
ENSMUST00000228232.2
ENSMUST00000227242.2
ENSMUST00000228748.2
heterogeneous nuclear ribonucleoprotein C
chr7_+_105385772 0.56 ENSMUST00000033182.10
integrin linked kinase
chr9_+_59198829 0.55 ENSMUST00000217570.2
ENSMUST00000026266.9
ADP-dependent glucokinase
chr11_-_69572648 0.52 ENSMUST00000005336.9
SUMO/sentrin specific peptidase 3
chr17_-_32539629 0.51 ENSMUST00000235702.2
ENSMUST00000236580.2
ENSMUST00000237860.2
A kinase (PRKA) anchor protein 8
chr14_-_52341472 0.50 ENSMUST00000111610.12
ENSMUST00000164655.2
heterogeneous nuclear ribonucleoprotein C
chr19_+_46064302 0.50 ENSMUST00000165017.2
ENSMUST00000223741.2
ENSMUST00000225780.2
nucleolar and coiled-body phosphoprotein 1
chr12_-_59266511 0.48 ENSMUST00000043204.8
F-box protein 33
chr9_+_108368032 0.47 ENSMUST00000166103.9
ENSMUST00000085044.14
ENSMUST00000193678.6
ENSMUST00000178075.8
ubiquitin specific peptidase 19
chr4_+_62327010 0.47 ENSMUST00000084524.4
pre-mRNA processing factor 4
chr5_-_130284366 0.46 ENSMUST00000026387.11
SBDS ribosome maturation factor
chrX_-_36167148 0.45 ENSMUST00000239259.2
NF-kappaB repressing factor
chr11_+_62442502 0.44 ENSMUST00000136938.2
ubiquitin B
chr19_-_24454720 0.44 ENSMUST00000099556.2
family with sequence similarity 122, member A
chr11_+_54413698 0.44 ENSMUST00000108895.8
ENSMUST00000101206.10
Rap guanine nucleotide exchange factor (GEF) 6
chr17_+_85397980 0.43 ENSMUST00000095188.7
calmodulin-lysine N-methyltransferase
chr15_-_51728893 0.42 ENSMUST00000022925.10
eukaryotic translation initiation factor 3, subunit H
chr11_-_69572896 0.41 ENSMUST00000066760.8
SUMO/sentrin specific peptidase 3
chr17_-_64638814 0.37 ENSMUST00000172733.2
praja ring finger ubiquitin ligase 2
chr2_+_31560725 0.36 ENSMUST00000038474.14
ENSMUST00000137156.2
exosome component 2
chr14_+_30741115 0.36 ENSMUST00000112094.8
ENSMUST00000144009.2
polybromo 1
chr11_-_115915315 0.35 ENSMUST00000016703.8
H3.3 histone B
chr13_+_49806772 0.33 ENSMUST00000223264.2
ENSMUST00000221142.2
ENSMUST00000222333.2
ENSMUST00000021824.8
nucleolar protein 8
chr1_+_52047368 0.33 ENSMUST00000027277.7
signal transducer and activator of transcription 4
chr17_-_64638887 0.32 ENSMUST00000172818.8
praja ring finger ubiquitin ligase 2
chr11_-_102076028 0.32 ENSMUST00000107156.9
ENSMUST00000021297.6
LSM12 homolog
chr14_-_31807552 0.32 ENSMUST00000022461.11
ENSMUST00000067955.12
ENSMUST00000124303.9
diphthamine biosynthesis 3
chr11_-_43638790 0.30 ENSMUST00000048578.3
ENSMUST00000109278.8
tetratricopeptide repeat domain 1
chr16_+_55794244 0.29 ENSMUST00000050248.9
zinc finger and BTB domain containing 11
chr11_+_17001586 0.29 ENSMUST00000131515.2
cannabinoid receptor interacting protein 1
chrX_+_138381109 0.27 ENSMUST00000046763.13
ENSMUST00000113030.3
RPA1 related single stranded DNA binding protein, X-linked
chr11_+_54413673 0.26 ENSMUST00000102743.10
Rap guanine nucleotide exchange factor (GEF) 6
chr7_-_128063354 0.26 ENSMUST00000106226.9
ENSMUST00000106228.8
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr7_-_128063037 0.25 ENSMUST00000165023.8
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr5_-_145077048 0.25 ENSMUST00000031627.9
PDGFA associated protein 1
chr4_+_40970906 0.25 ENSMUST00000091614.7
ENSMUST00000030133.15
ENSMUST00000098143.11
nuclear transcription factor, X-box binding 1
chr16_+_17716480 0.25 ENSMUST00000055374.8
testis-specific serine kinase 2
chr2_+_69553384 0.24 ENSMUST00000040915.15
peptidyl-prolyl isomerase G (cyclophilin G)
chr2_+_69553141 0.23 ENSMUST00000090858.10
peptidyl-prolyl isomerase G (cyclophilin G)
chr13_+_49806542 0.18 ENSMUST00000222197.2
ENSMUST00000221083.2
ENSMUST00000223467.2
nucleolar protein 8
chr3_-_123029745 0.18 ENSMUST00000106426.8
synaptopodin 2
chr7_-_128063053 0.18 ENSMUST00000141126.8
ENSMUST00000033135.9
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr1_-_37469037 0.17 ENSMUST00000027286.7
cytochrome C oxidase assembly factor 5
chr16_-_97564910 0.16 ENSMUST00000019386.10
receptor-interacting serine-threonine kinase 4
chr9_+_108367801 0.16 ENSMUST00000006854.13
ubiquitin specific peptidase 19
chr3_-_123029782 0.14 ENSMUST00000106427.8
ENSMUST00000198584.2
synaptopodin 2
chrX_+_150305348 0.14 ENSMUST00000148622.3
PHD finger protein 8
chrX_-_7765171 0.11 ENSMUST00000115655.8
ENSMUST00000156741.8
polyglutamine binding protein 1
chr10_-_62285458 0.11 ENSMUST00000020273.16
suppressor of var1, 3-like 1 (S. cerevisiae)
chrX_-_7765096 0.09 ENSMUST00000154552.2
polyglutamine binding protein 1
chr12_+_110816687 0.09 ENSMUST00000221549.2
ENSMUST00000170060.4
zinc finger protein 839
chr12_+_110816738 0.08 ENSMUST00000222460.2
zinc finger protein 839
chr19_+_5091365 0.07 ENSMUST00000116567.4
ENSMUST00000235918.2
breast cancer metastasis-suppressor 1
chr11_-_16952929 0.06 ENSMUST00000156101.2
pleckstrin
chr14_+_51162635 0.04 ENSMUST00000128395.2
apurinic/apyrimidinic endonuclease 1
chr6_-_39702381 0.04 ENSMUST00000002487.15
Braf transforming gene
chr17_+_84819260 0.03 ENSMUST00000047206.7
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr19_+_41818409 0.02 ENSMUST00000087155.5
frequently rearranged in advanced T cell lymphomas
chr3_-_90416757 0.00 ENSMUST00000107343.8
ENSMUST00000001043.14
ENSMUST00000107344.8
ENSMUST00000076639.11
ENSMUST00000107346.8
ENSMUST00000146740.8
ENSMUST00000107342.2
ENSMUST00000049937.13
chromatin target of PRMT1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
1.3 4.0 GO:1990428 miRNA transport(GO:1990428)
1.3 5.3 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.1 4.4 GO:0006014 D-ribose metabolic process(GO:0006014)
0.9 2.7 GO:0006404 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.8 5.4 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.7 5.1 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.6 3.0 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.5 3.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.5 1.9 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.5 7.2 GO:0033572 transferrin transport(GO:0033572)
0.4 2.1 GO:0009597 detection of virus(GO:0009597)
0.4 1.8 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.4 1.1 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.3 1.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 1.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.3 4.8 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.3 1.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.7 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 1.8 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.2 1.3 GO:0002326 B cell lineage commitment(GO:0002326)
0.2 1.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 2.4 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.2 1.8 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.2 3.9 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.2 1.1 GO:0015871 choline transport(GO:0015871)
0.2 1.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 1.7 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 1.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 2.1 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 2.9 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1 3.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 2.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 1.9 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.1 1.0 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 1.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.7 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 2.3 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.1 0.6 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 1.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 1.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.5 GO:0048539 mature ribosome assembly(GO:0042256) bone marrow development(GO:0048539)
0.1 0.4 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 5.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 0.9 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 1.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 4.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.5 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 1.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 5.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.1 GO:0061187 histone H4-K20 demethylation(GO:0035574) regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 1.4 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 1.6 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 3.8 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 1.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 3.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 1.5 GO:0006414 translational elongation(GO:0006414)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 2.0 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 3.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 5.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 2.6 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.1 GO:0030845 regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0030033 microvillus assembly(GO:0030033)
0.0 1.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.7 GO:0006284 base-excision repair(GO:0006284)
0.0 0.7 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.0 0.7 GO:0017145 stem cell division(GO:0017145)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:1990879 CST complex(GO:1990879)
0.9 5.3 GO:0097149 centralspindlin complex(GO:0097149)
0.9 2.6 GO:1990423 RZZ complex(GO:1990423)
0.6 7.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.5 3.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.4 1.1 GO:0005584 collagen type I trimer(GO:0005584)
0.4 1.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.3 2.7 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 3.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 5.0 GO:0071004 U2-type prespliceosome(GO:0071004)
0.2 1.8 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.2 2.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 1.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 2.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 2.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 5.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 0.5 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 2.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 1.2 GO:0097413 Lewy body(GO:0097413)
0.1 3.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 5.5 GO:0032590 dendrite membrane(GO:0032590)
0.1 8.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.9 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 3.3 GO:0090544 BAF-type complex(GO:0090544)
0.1 1.1 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 4.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.6 GO:0045120 pronucleus(GO:0045120)
0.0 1.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 3.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.9 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 9.6 GO:0016607 nuclear speck(GO:0016607)
0.0 1.4 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.2 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 2.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 5.4 GO:0016604 nuclear body(GO:0016604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.2 GO:0004998 transferrin receptor activity(GO:0004998)
1.3 3.9 GO:0097677 STAT family protein binding(GO:0097677)
0.6 7.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.6 1.8 GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.6 3.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.6 2.8 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.4 4.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 1.0 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.3 3.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3 2.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.3 1.6 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 1.8 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 0.7 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 4.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 2.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 5.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 3.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 4.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 1.7 GO:0008097 5S rRNA binding(GO:0008097)
0.1 2.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 5.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.5 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 1.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 2.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 2.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 4.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 2.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 5.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 4.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.5 GO:0019843 rRNA binding(GO:0019843)
0.0 9.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 3.6 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 3.9 GO:0008017 microtubule binding(GO:0008017)
0.0 1.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 5.3 PID AURORA B PATHWAY Aurora B signaling
0.1 2.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 6.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 4.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.2 PID ATR PATHWAY ATR signaling pathway
0.0 1.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 9.3 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2 3.0 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 7.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 5.3 REACTOME KINESINS Genes involved in Kinesins
0.1 3.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 14.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 10.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 3.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.8 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 1.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 2.4 REACTOME TRANSLATION Genes involved in Translation
0.0 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling