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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Gzf1

Z-value: 0.64

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Transcription factors associated with Gzf1

Gene Symbol Gene ID Gene Info
Gzf1
ENSMUSG00000027439.10 Gzf1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gzf1mm39_v1_chr2_+_148522943_1485230700.271.1e-01Click!

Activity profile of Gzf1 motif

Sorted Z-values of Gzf1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Gzf1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_133856025 3.48 ENSMUST00000105879.2
ENSMUST00000030651.9
Sh3bgrl3
SH3 domain binding glutamic acid-rich protein-like 3
chr17_+_47905553 3.00 ENSMUST00000182846.3
Ccnd3
cyclin D3
chr11_-_33113071 1.90 ENSMUST00000093201.13
ENSMUST00000101375.5
ENSMUST00000109354.10
ENSMUST00000075641.10
Npm1
nucleophosmin 1
chr8_-_79235505 1.57 ENSMUST00000211719.2
ENSMUST00000049245.10
Rbmxl1
RNA binding motif protein, X-linked like-1
chr14_+_19801333 1.30 ENSMUST00000022340.5
Nid2
nidogen 2
chr4_+_129407374 1.21 ENSMUST00000062356.7
Marcksl1
MARCKS-like 1
chr8_+_23901506 1.18 ENSMUST00000033952.8
Sfrp1
secreted frizzled-related protein 1
chr4_-_129436465 1.02 ENSMUST00000102597.5
Hdac1
histone deacetylase 1
chr2_+_162773440 0.89 ENSMUST00000130411.7
ENSMUST00000126163.3
Srsf6
serine and arginine-rich splicing factor 6
chr12_+_85645801 0.74 ENSMUST00000177587.9
Jdp2
Jun dimerization protein 2
chr7_-_30312246 0.63 ENSMUST00000006476.6
Upk1a
uroplakin 1A
chr1_+_180553569 0.60 ENSMUST00000027780.6
Acbd3
acyl-Coenzyme A binding domain containing 3
chr6_-_52181393 0.46 ENSMUST00000048794.7
Hoxa5
homeobox A5
chr9_-_116004386 0.42 ENSMUST00000035014.8
Tgfbr2
transforming growth factor, beta receptor II
chr8_+_106581719 0.40 ENSMUST00000040445.9
Thap11
THAP domain containing 11
chr10_+_82534841 0.38 ENSMUST00000020478.14
Hcfc2
host cell factor C2
chr7_-_103778992 0.37 ENSMUST00000053743.6
Ubqln5
ubiquilin 5
chr8_+_79236051 0.27 ENSMUST00000209992.2
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr17_+_5045178 0.20 ENSMUST00000092723.11
ENSMUST00000232180.2
ENSMUST00000115797.9
Arid1b
AT rich interactive domain 1B (SWI-like)
chr1_+_15875846 0.19 ENSMUST00000188371.7
ENSMUST00000027057.8
Terf1
telomeric repeat binding factor 1
chr17_+_71511642 0.13 ENSMUST00000126681.8
Lpin2
lipin 2
chr16_+_65612083 0.10 ENSMUST00000168064.3
Vgll3
vestigial like family member 3
chr14_+_52860023 0.02 ENSMUST00000103570.2
Trav5-1
T cell receptor alpha variable 5-1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0006407 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407)
0.4 1.2 GO:2000041 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 1.0 GO:2000676 fungiform papilla formation(GO:0061198) positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 0.5 GO:0060435 bronchiole development(GO:0060435) intestinal epithelial cell maturation(GO:0060574)
0.1 0.4 GO:0002663 B cell tolerance induction(GO:0002514) regulation of tolerance induction to self antigen(GO:0002649) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 3.0 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.9 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.2 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 1.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 3.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.0 0.7 GO:0031065 positive regulation of histone deacetylation(GO:0031065)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 1.9 GO:0001652 granular component(GO:0001652)
0.1 1.0 GO:0016580 Sin3 complex(GO:0016580)
0.0 3.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 3.5 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.2 1.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 3.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 3.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.9 GO:0036002 pre-mRNA binding(GO:0036002)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 3.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 3.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)