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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hes5_Hes7

Z-value: 1.75

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Transcription factors associated with Hes5_Hes7

Gene Symbol Gene ID Gene Info
Hes5
ENSMUSG00000048001.8 Hes5
Hes7
ENSMUSG00000023781.3 Hes7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hes7mm39_v1_chr11_+_69011230_690112300.651.8e-05Click!
Hes5mm39_v1_chr4_+_155045372_1550453870.447.0e-03Click!

Activity profile of Hes5_Hes7 motif

Sorted Z-values of Hes5_Hes7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hes5_Hes7

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chrX_+_8137372 17.27 ENSMUST00000127103.8
ENSMUST00000115591.8
Slc38a5
solute carrier family 38, member 5
chrX_+_8137620 16.30 ENSMUST00000033512.11
Slc38a5
solute carrier family 38, member 5
chr11_-_11976732 15.88 ENSMUST00000143915.2
Grb10
growth factor receptor bound protein 10
chrX_+_8137881 15.07 ENSMUST00000115590.2
Slc38a5
solute carrier family 38, member 5
chr11_-_11976237 12.73 ENSMUST00000150972.8
Grb10
growth factor receptor bound protein 10
chr17_-_26417982 12.15 ENSMUST00000142410.2
ENSMUST00000120333.8
ENSMUST00000039113.14
Pdia2
protein disulfide isomerase associated 2
chr13_+_108452866 10.67 ENSMUST00000051594.12
Depdc1b
DEP domain containing 1B
chr13_+_108452930 7.53 ENSMUST00000171178.2
Depdc1b
DEP domain containing 1B
chr4_+_134195631 7.48 ENSMUST00000030636.11
ENSMUST00000127279.8
ENSMUST00000105867.8
Stmn1
stathmin 1
chr9_-_21874802 6.49 ENSMUST00000006397.7
Epor
erythropoietin receptor
chr12_+_109425769 5.93 ENSMUST00000173812.2
Dlk1
delta like non-canonical Notch ligand 1
chr2_+_150412329 5.64 ENSMUST00000089200.3
Cst7
cystatin F (leukocystatin)
chr15_-_78739717 4.94 ENSMUST00000044584.6
Lgals2
lectin, galactose-binding, soluble 2
chr6_+_72074718 3.98 ENSMUST00000187007.3
St3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr5_+_31409021 3.59 ENSMUST00000054829.13
ENSMUST00000201625.4
ENSMUST00000201937.4
Krtcap3
keratinocyte associated protein 3
chr6_+_72074545 3.55 ENSMUST00000069994.11
ENSMUST00000114112.4
St3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr9_+_107464841 3.53 ENSMUST00000010192.11
Ifrd2
interferon-related developmental regulator 2
chr17_-_25493273 3.05 ENSMUST00000172587.8
ENSMUST00000049911.16
ENSMUST00000173713.8
Ube2i
ubiquitin-conjugating enzyme E2I
chr1_+_172327812 2.89 ENSMUST00000192460.2
Tagln2
transgelin 2
chr17_-_15181491 2.85 ENSMUST00000024657.12
Phf10
PHD finger protein 10
chr6_+_35154545 2.69 ENSMUST00000170234.2
Nup205
nucleoporin 205
chr3_-_95763065 2.50 ENSMUST00000161476.8
Prpf3
pre-mRNA processing factor 3
chr9_-_107167046 2.34 ENSMUST00000035194.8
Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr3_-_95763160 2.34 ENSMUST00000015892.14
Prpf3
pre-mRNA processing factor 3
chr17_-_25492832 2.32 ENSMUST00000172868.8
ENSMUST00000172618.8
Ube2i
ubiquitin-conjugating enzyme E2I
chr4_+_154954042 2.05 ENSMUST00000079269.14
ENSMUST00000163732.8
ENSMUST00000080559.13
Mmel1
membrane metallo-endopeptidase-like 1
chr17_+_48623157 1.85 ENSMUST00000049614.13
B430306N03Rik
RIKEN cDNA B430306N03 gene
chr17_+_36172210 1.83 ENSMUST00000074259.15
ENSMUST00000174873.2
Nrm
nurim (nuclear envelope membrane protein)
chr11_+_3913970 1.81 ENSMUST00000109985.8
ENSMUST00000020705.5
Pes1
pescadillo ribosomal biogenesis factor 1
chr1_-_192718064 1.74 ENSMUST00000215093.2
ENSMUST00000195354.6
Syt14
synaptotagmin XIV
chrX_-_9123138 1.68 ENSMUST00000115553.3
Gm14862
predicted gene 14862
chr11_+_101207021 1.66 ENSMUST00000142640.8
ENSMUST00000019470.14
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr10_+_85665234 1.56 ENSMUST00000217667.2
Pwp1
PWP1 homolog, endonuclein
chr2_-_92201342 1.33 ENSMUST00000176810.8
ENSMUST00000090582.11
ENSMUST00000068586.13
Large2
LARGE xylosyl- and glucuronyltransferase 2
chr1_-_188740023 1.10 ENSMUST00000085678.8
Kctd3
potassium channel tetramerisation domain containing 3
chr1_-_161704224 1.10 ENSMUST00000048377.11
Suco
SUN domain containing ossification factor
chr4_-_43562397 1.07 ENSMUST00000030187.14
Tln1
talin 1
chr4_+_32657105 1.06 ENSMUST00000071642.11
ENSMUST00000178134.2
Mdn1
midasin AAA ATPase 1
chr19_+_47167259 1.05 ENSMUST00000111808.11
Neurl1a
neuralized E3 ubiquitin protein ligase 1A
chr9_-_36637923 1.00 ENSMUST00000034625.12
Chek1
checkpoint kinase 1
chr15_-_98507913 0.99 ENSMUST00000226500.2
ENSMUST00000227501.2
Adcy6
adenylate cyclase 6
chr17_+_28945057 0.98 ENSMUST00000233003.2
Gm4356
predicted gene 4356
chr2_+_91357100 0.93 ENSMUST00000111338.10
Ckap5
cytoskeleton associated protein 5
chr1_-_192717958 0.93 ENSMUST00000016344.9
Syt14
synaptotagmin XIV
chr1_-_75195127 0.87 ENSMUST00000079464.13
Tuba4a
tubulin, alpha 4A
chr1_-_75195889 0.80 ENSMUST00000186213.7
Tuba4a
tubulin, alpha 4A
chr9_+_20563386 0.79 ENSMUST00000034689.8
Pin1
protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
chr9_-_36637670 0.70 ENSMUST00000172702.9
ENSMUST00000172742.2
Chek1
checkpoint kinase 1
chr18_+_37453427 0.70 ENSMUST00000078271.4
Pcdhb5
protocadherin beta 5
chr8_-_25438784 0.66 ENSMUST00000119720.8
ENSMUST00000121438.9
Adam32
a disintegrin and metallopeptidase domain 32
chr11_+_79883885 0.64 ENSMUST00000163272.2
ENSMUST00000017692.15
Suz12
SUZ12 polycomb repressive complex 2 subunit
chr14_-_30740946 0.63 ENSMUST00000228341.2
Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr7_-_130964469 0.62 ENSMUST00000059438.11
2310057M21Rik
RIKEN cDNA 2310057M21 gene
chr6_-_52203146 0.58 ENSMUST00000114425.3
Hoxa9
homeobox A9
chr18_-_38131766 0.56 ENSMUST00000236588.2
ENSMUST00000237272.2
ENSMUST00000236134.2
Arap3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr6_+_127538268 0.52 ENSMUST00000212051.2
Cracr2a
calcium release activated channel regulator 2A
chr3_+_104545974 0.51 ENSMUST00000046212.2
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr4_-_132484559 0.51 ENSMUST00000030709.9
Smpdl3b
sphingomyelin phosphodiesterase, acid-like 3B
chr14_-_69945022 0.48 ENSMUST00000118374.8
R3hcc1
R3H domain and coiled-coil containing 1
chr18_-_35855383 0.47 ENSMUST00000133064.8
Ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr4_-_133484080 0.46 ENSMUST00000008024.7
Arid1a
AT rich interactive domain 1A (SWI-like)
chr10_+_36850532 0.42 ENSMUST00000019911.14
ENSMUST00000105510.2
Hdac2
histone deacetylase 2
chr11_+_58197881 0.40 ENSMUST00000153510.9
Zfp692
zinc finger protein 692
chr14_-_69944942 0.39 ENSMUST00000121142.4
R3hcc1
R3H domain and coiled-coil containing 1
chr15_-_37004302 0.37 ENSMUST00000228275.2
Zfp706
zinc finger protein 706
chr8_+_125448867 0.35 ENSMUST00000034463.4
Arv1
ARV1 homolog, fatty acid homeostasis modulator
chr16_+_45044678 0.34 ENSMUST00000102802.10
ENSMUST00000063654.6
Btla
B and T lymphocyte associated
chr19_+_8713156 0.32 ENSMUST00000210512.2
ENSMUST00000049424.11
Wdr74
WD repeat domain 74
chr1_-_131161312 0.29 ENSMUST00000212202.2
Rassf5
Ras association (RalGDS/AF-6) domain family member 5
chrX_-_8042129 0.28 ENSMUST00000143984.2
Tbc1d25
TBC1 domain family, member 25
chr9_-_78350486 0.26 ENSMUST00000070742.14
ENSMUST00000034898.14
Cgas
cyclic GMP-AMP synthase
chr2_-_92201311 0.25 ENSMUST00000176774.8
Large2
LARGE xylosyl- and glucuronyltransferase 2
chr10_-_57408512 0.24 ENSMUST00000169122.8
Serinc1
serine incorporator 1
chr11_+_54757200 0.24 ENSMUST00000020504.6
Hint1
histidine triad nucleotide binding protein 1
chr8_+_13155621 0.22 ENSMUST00000016680.14
ENSMUST00000121426.2
Cul4a
cullin 4A
chr11_+_4587733 0.19 ENSMUST00000070257.14
ENSMUST00000109930.3
Ascc2
activating signal cointegrator 1 complex subunit 2
chr9_+_75221415 0.18 ENSMUST00000215875.2
Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr6_-_145021816 0.18 ENSMUST00000111742.8
ENSMUST00000048252.11
Bcat1
branched chain aminotransferase 1, cytosolic
chr15_+_101982208 0.14 ENSMUST00000169681.3
ENSMUST00000229400.2
Eif4b
eukaryotic translation initiation factor 4B
chr16_-_33787399 0.14 ENSMUST00000023510.7
Umps
uridine monophosphate synthetase
chr11_-_59678462 0.14 ENSMUST00000125307.2
Pld6
phospholipase D family, member 6
chr11_+_22462088 0.14 ENSMUST00000059319.8
Tmem17
transmembrane protein 17
chr10_+_79518002 0.14 ENSMUST00000020550.13
Cdc34
cell division cycle 34
chr12_+_77285770 0.11 ENSMUST00000062804.8
Fut8
fucosyltransferase 8
chr4_+_123798690 0.10 ENSMUST00000106202.4
Mycbp
MYC binding protein
chr10_-_80223475 0.10 ENSMUST00000105350.3
Mex3d
mex3 RNA binding family member D
chr6_+_71520855 0.09 ENSMUST00000204535.2
ENSMUST00000065364.5
ENSMUST00000204199.2
Chmp3
charged multivesicular body protein 3
chr15_+_38662158 0.07 ENSMUST00000022904.8
ENSMUST00000228820.2
Atp6v1c1
ATPase, H+ transporting, lysosomal V1 subunit C1
chr3_-_95148909 0.06 ENSMUST00000090815.6
ENSMUST00000107197.2
Gm128
predicted gene 128
chr9_+_64028783 0.06 ENSMUST00000118215.3
Lctl
lactase-like
chr4_+_123798625 0.04 ENSMUST00000030400.14
Mycbp
MYC binding protein
chr5_+_122788469 0.02 ENSMUST00000199371.2
P2rx7
purinergic receptor P2X, ligand-gated ion channel, 7
chr5_+_43672856 0.01 ENSMUST00000076939.10
C1qtnf7
C1q and tumor necrosis factor related protein 7
chr10_+_79518138 0.00 ENSMUST00000166603.2
ENSMUST00000219791.2
ENSMUST00000219930.2
ENSMUST00000218964.2
Cdc34
cell division cycle 34

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 28.6 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
2.7 48.7 GO:0015816 glycine transport(GO:0015816)
1.1 7.5 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.9 5.4 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.6 1.7 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.4 6.5 GO:0061032 visceral serous pericardium development(GO:0061032)
0.4 4.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 1.0 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.3 1.6 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.2 10.5 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.2 2.3 GO:0044351 macropinocytosis(GO:0044351)
0.2 0.9 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 5.9 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.2 2.7 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 0.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) nucleolus organization(GO:0007000)
0.1 1.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 7.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 18.5 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.1 0.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 1.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.4 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0007315 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.0 0.5 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 5.2 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 1.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.6 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.1 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.3 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 2.7 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 1.7 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.1 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.4 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.4 2.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 1.7 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.8 GO:0070545 PeBoW complex(GO:0070545)
0.2 4.8 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 3.3 GO:0071564 npBAF complex(GO:0071564)
0.1 1.8 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 1.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 1.0 GO:0097440 apical dendrite(GO:0097440)
0.0 44.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 7.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.7 GO:0005657 replication fork(GO:0005657)
0.0 8.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 48.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
2.5 7.5 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.0 12.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.9 5.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.5 4.9 GO:0016936 galactoside binding(GO:0016936)
0.4 28.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.4 1.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 1.0 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
0.2 1.6 GO:0042285 xylosyltransferase activity(GO:0042285)
0.2 2.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.4 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.1 0.8 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 2.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 5.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 6.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 14.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.7 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 7.5 GO:0015631 tubulin binding(GO:0015631)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 28.6 PID IGF1 PATHWAY IGF1 pathway
0.3 5.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 1.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 12.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.5 PID EPO PATHWAY EPO signaling pathway
0.1 2.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 6.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 4.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 28.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.7 48.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 5.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 5.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 18.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 1.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes