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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hey2

Z-value: 1.75

Motif logo

Transcription factors associated with Hey2

Gene Symbol Gene ID Gene Info
ENSMUSG00000019789.10 Hey2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hey2mm39_v1_chr10_-_30718760_307187970.734.6e-07Click!

Activity profile of Hey2 motif

Sorted Z-values of Hey2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hey2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_128745214 6.10 ENSMUST00000220308.2
CD63 antigen
chr7_-_4755971 4.46 ENSMUST00000183971.8
ENSMUST00000182173.2
ENSMUST00000182738.8
ENSMUST00000182111.8
ENSMUST00000184143.8
ENSMUST00000182048.2
ENSMUST00000063324.14
cytochrome c oxidase subunit 6B2
chr7_+_78563964 4.38 ENSMUST00000120331.4
interferon-stimulated protein
chr4_+_134195631 4.36 ENSMUST00000030636.11
ENSMUST00000127279.8
ENSMUST00000105867.8
stathmin 1
chr10_+_12966532 4.30 ENSMUST00000121646.8
ENSMUST00000121325.8
ENSMUST00000121766.8
pleiomorphic adenoma gene-like 1
chr2_-_150510116 4.01 ENSMUST00000028944.4
acyl-CoA synthetase short-chain family member 1
chr7_+_78564062 3.85 ENSMUST00000205981.2
interferon-stimulated protein
chr17_-_26417982 3.74 ENSMUST00000142410.2
ENSMUST00000120333.8
ENSMUST00000039113.14
protein disulfide isomerase associated 2
chr2_-_93164812 3.58 ENSMUST00000111265.9
tetraspanin 18
chr17_+_36172210 3.35 ENSMUST00000074259.15
ENSMUST00000174873.2
nurim (nuclear envelope membrane protein)
chr5_-_44259010 3.31 ENSMUST00000087441.11
prominin 1
chr3_+_51131868 3.23 ENSMUST00000023849.15
ENSMUST00000167780.2
nocturnin
chr8_-_71060911 3.18 ENSMUST00000210580.2
ENSMUST00000211608.2
ENSMUST00000049908.11
single stranded DNA binding protein 4
chr7_-_125968653 3.09 ENSMUST00000205642.2
ENSMUST00000032997.8
ENSMUST00000206793.2
linker for activation of T cells
chr15_-_78739717 3.08 ENSMUST00000044584.6
lectin, galactose-binding, soluble 2
chrX_+_70599524 2.94 ENSMUST00000072699.13
ENSMUST00000114582.9
ENSMUST00000015361.11
ENSMUST00000088874.10
high mobility group box 3
chr5_+_100993996 2.66 ENSMUST00000112887.8
ENSMUST00000031255.15
glycerol-3-phosphate acyltransferase 3
chr5_-_122187884 2.60 ENSMUST00000111752.10
cut-like homeobox 2
chr12_+_117807224 2.60 ENSMUST00000021592.16
cell division cycle associated 7 like
chr17_-_71617945 2.60 ENSMUST00000232777.2
ENSMUST00000024849.11
elastin microfibril interfacer 2
chr6_-_88852017 2.56 ENSMUST00000145944.3
podocalyxin-like 2
chr5_+_143534455 2.56 ENSMUST00000169329.8
ENSMUST00000067145.12
ENSMUST00000119488.2
ENSMUST00000118121.2
ENSMUST00000200267.2
ENSMUST00000196487.2
family with sequence similarity 220, member A
family with sequence similarity 220, member A
chr7_+_141027557 2.52 ENSMUST00000106004.8
ribosomal protein, large P2
chr1_+_59724108 2.51 ENSMUST00000027174.10
ENSMUST00000190231.7
ENSMUST00000191142.7
ENSMUST00000185772.7
NOP58 ribonucleoprotein
chr14_-_70588803 2.47 ENSMUST00000143153.2
ENSMUST00000127000.2
ENSMUST00000068044.14
ENSMUST00000022688.10
solute carrier family 39 (zinc transporter), member 14
chr12_+_117807607 2.43 ENSMUST00000176735.8
ENSMUST00000177339.2
cell division cycle associated 7 like
chr4_-_120427449 2.37 ENSMUST00000030381.8
cytidine 5'-triphosphate synthase
chr14_-_30741012 2.34 ENSMUST00000037739.8
guanine nucleotide binding protein-like 3 (nucleolar)
chr1_+_180731843 2.29 ENSMUST00000027802.9
pyrroline-5-carboxylate reductase family, member 2
chr11_+_113510135 2.23 ENSMUST00000146390.3
somatostatin receptor 2
chr11_+_103857541 2.20 ENSMUST00000057921.10
ENSMUST00000063347.12
ADP-ribosylation factor 2
chr3_-_88410495 2.17 ENSMUST00000120377.8
ENSMUST00000029699.13
lamin A
chr5_+_100994230 2.12 ENSMUST00000092990.4
ENSMUST00000145612.2
glycerol-3-phosphate acyltransferase 3
chr6_-_88851579 2.11 ENSMUST00000061262.11
ENSMUST00000140455.8
ENSMUST00000145780.2
podocalyxin-like 2
chr1_+_88334678 2.07 ENSMUST00000027518.12
secreted phosphoprotein 2
chr10_-_117212860 2.07 ENSMUST00000069168.13
ENSMUST00000176686.8
cleavage and polyadenylation specific factor 6
chr19_+_37538843 2.02 ENSMUST00000066439.8
ENSMUST00000238817.2
exocyst complex component 6
chr17_-_71617968 2.00 ENSMUST00000233057.2
elastin microfibril interfacer 2
chr10_-_117212826 1.92 ENSMUST00000177145.8
ENSMUST00000176670.8
cleavage and polyadenylation specific factor 6
chr15_+_80556023 1.92 ENSMUST00000023044.7
family with sequence similarity 83, member F
chr4_-_11965691 1.91 ENSMUST00000108301.8
ENSMUST00000095144.10
ENSMUST00000108302.8
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr7_-_64041996 1.90 ENSMUST00000032735.8
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr4_-_117013396 1.86 ENSMUST00000102696.5
ribosomal protein S8
chr12_+_30961650 1.75 ENSMUST00000020997.15
ENSMUST00000110880.3
Sh3 domain YSC-like 1
chr14_-_71003973 1.73 ENSMUST00000226448.2
ENSMUST00000022696.8
exportin 7
chr17_+_47922497 1.70 ENSMUST00000024778.3
mediator complex subunit 20
chr9_-_103357564 1.68 ENSMUST00000124310.5
beaded filament structural protein 2, phakinin
chr4_-_148172423 1.67 ENSMUST00000030865.9
angiotensin II, type I receptor-associated protein
chr3_-_89325594 1.67 ENSMUST00000029679.4
CDC28 protein kinase 1b
chr9_-_53521585 1.60 ENSMUST00000034547.6
acetyl-Coenzyme A acetyltransferase 1
chrX_+_49930311 1.57 ENSMUST00000114887.9
serine/threonine kinase 26
chr4_+_128548479 1.54 ENSMUST00000030588.13
ENSMUST00000136377.8
polyhomeotic 2
chr3_-_90297187 1.51 ENSMUST00000029541.12
solute carrier family 27 (fatty acid transporter), member 3
chr11_-_106278892 1.51 ENSMUST00000106813.9
ENSMUST00000141146.2
intercellular adhesion molecule 2
chr11_-_58059293 1.46 ENSMUST00000172035.8
ENSMUST00000035604.13
ENSMUST00000102711.9
gem nuclear organelle associated protein 5
chr1_-_152642032 1.45 ENSMUST00000111859.8
ral guanine nucleotide dissociation stimulator,-like 1
chr5_+_139777263 1.43 ENSMUST00000018287.10
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
chr13_+_51562675 1.41 ENSMUST00000087978.5
sphingosine-1-phosphate receptor 3
chr6_+_125108829 1.40 ENSMUST00000044200.11
ENSMUST00000204185.2
NOP2 nucleolar protein
chr14_-_71004019 1.40 ENSMUST00000167242.8
exportin 7
chr12_+_86725459 1.37 ENSMUST00000021681.4
vasohibin 1
chr8_+_106245368 1.35 ENSMUST00000034363.7
hydroxysteroid 11-beta dehydrogenase 2
chr1_-_152642073 1.35 ENSMUST00000111857.3
ral guanine nucleotide dissociation stimulator,-like 1
chr10_+_7543260 1.31 ENSMUST00000040135.9
nucleoporin 43
chr17_-_31731222 1.29 ENSMUST00000236665.2
WD repeat domain 4
chr3_+_104545974 1.27 ENSMUST00000046212.2
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr11_+_113510207 1.26 ENSMUST00000106630.2
somatostatin receptor 2
chr2_+_31840151 1.22 ENSMUST00000001920.13
ENSMUST00000151276.3
allograft inflammatory factor 1-like
chrX_-_7940959 1.16 ENSMUST00000115636.4
ENSMUST00000115638.10
suppressor of variegation 3-9 1
chr19_+_47568041 1.14 ENSMUST00000026043.12
STE20-like kinase
chr5_+_129802127 1.14 ENSMUST00000086046.10
ENSMUST00000186265.6
nipsnap homolog 2
chr14_-_30740946 1.08 ENSMUST00000228341.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr4_+_155976279 1.05 ENSMUST00000105584.10
ENSMUST00000079031.6
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr17_-_47922374 1.02 ENSMUST00000024783.9
bystin-like
chr6_+_119152210 0.98 ENSMUST00000112777.9
ENSMUST00000073909.6
decapping mRNA 1B
chr17_-_33937565 0.95 ENSMUST00000174040.2
ENSMUST00000173015.8
ENSMUST00000066121.13
ENSMUST00000186022.7
ENSMUST00000173329.8
ENSMUST00000172767.9
membrane associated ring-CH-type finger 2
chr17_-_31731190 0.94 ENSMUST00000237127.2
WD repeat domain 4
chr6_-_89339581 0.93 ENSMUST00000163139.8
plexin A1
chr7_-_66077215 0.92 ENSMUST00000015278.15
aldehyde dehydrogenase family 1, subfamily A3
chr4_-_129534752 0.92 ENSMUST00000132217.8
ENSMUST00000130017.2
ENSMUST00000154105.8
taxilin alpha
chr19_+_36811615 0.89 ENSMUST00000025729.12
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr1_+_23801007 0.86 ENSMUST00000063663.6
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr5_+_122534900 0.86 ENSMUST00000196969.5
actin related protein 2/3 complex, subunit 3
chr10_-_112764879 0.84 ENSMUST00000099276.4
ataxin 7-like 3B
chr18_+_68433422 0.84 ENSMUST00000009679.11
ENSMUST00000131075.8
ENSMUST00000025427.14
ENSMUST00000139111.2
RNA (guanine-7-) methyltransferase
chr13_-_114595475 0.81 ENSMUST00000022287.8
ENSMUST00000223640.3
follistatin
chr17_+_48047955 0.81 ENSMUST00000086932.10
transcription factor EB
chr1_-_156767123 0.79 ENSMUST00000189316.7
ENSMUST00000190648.7
ENSMUST00000172057.8
ENSMUST00000191605.7
Ral GEF with PH domain and SH3 binding motif 2
chr19_+_6952580 0.78 ENSMUST00000237084.2
ENSMUST00000236218.2
ENSMUST00000237235.2
protein phosphatase 1, regulatory inhibitor subunit 14B
chr1_-_133589020 0.78 ENSMUST00000193504.6
ENSMUST00000195067.2
ENSMUST00000191896.6
ENSMUST00000194668.6
ENSMUST00000195424.6
ENSMUST00000179598.4
ENSMUST00000027736.13
zinc finger CCCH type containing 11A
predicted gene, 38394
zinc finger CCCH type containing 11A
chr1_-_156766957 0.78 ENSMUST00000171292.8
ENSMUST00000063199.13
ENSMUST00000027886.14
Ral GEF with PH domain and SH3 binding motif 2
chr5_+_52898910 0.77 ENSMUST00000031081.11
ENSMUST00000031082.8
phosphatidylinositol 4-kinase type 2 beta
chr1_-_120192977 0.76 ENSMUST00000140490.8
ENSMUST00000112640.8
STEAP family member 3
chr11_-_97591150 0.75 ENSMUST00000018681.14
polycomb group ring finger 2
chr9_+_107464841 0.75 ENSMUST00000010192.11
interferon-related developmental regulator 2
chr4_-_126861918 0.73 ENSMUST00000106108.9
zinc finger, MYM-type 4
chr18_-_36587573 0.71 ENSMUST00000025204.7
ENSMUST00000237792.2
prefoldin 1
chr1_-_30988772 0.71 ENSMUST00000238874.2
ENSMUST00000027232.15
ENSMUST00000076587.6
ENSMUST00000233506.2
protein tyrosine phosphatase 4a1
chr5_-_139470169 0.70 ENSMUST00000150992.2
ENSMUST00000110851.8
ENSMUST00000079996.13
zinc finger, AN1-type domain 2A
chr8_+_72021567 0.70 ENSMUST00000034267.5
solute carrier family 27 (fatty acid transporter), member 1
chr14_-_56021484 0.69 ENSMUST00000170223.9
ENSMUST00000002398.9
ENSMUST00000227031.2
adenylate cyclase 4
chr9_-_36637923 0.69 ENSMUST00000034625.12
checkpoint kinase 1
chr11_+_61575245 0.67 ENSMUST00000093019.6
family with sequence similarity 83, member G
chr11_-_8574887 0.67 ENSMUST00000239091.2
tensin 3
chr7_+_140547941 0.66 ENSMUST00000106040.8
ENSMUST00000026564.9
interferon induced transmembrane protein 1
chr15_-_79339727 0.65 ENSMUST00000230599.2
casein kinase 1, epsilon
chr11_+_102080446 0.65 ENSMUST00000070334.10
glucose 6 phosphatase, catalytic, 3
chr4_-_11966367 0.64 ENSMUST00000056050.5
ENSMUST00000108299.2
ENSMUST00000108297.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_+_72021510 0.62 ENSMUST00000212889.2
solute carrier family 27 (fatty acid transporter), member 1
chr6_-_28421678 0.62 ENSMUST00000090511.4
golgi coiled coil 1
chr18_+_5035072 0.61 ENSMUST00000210707.2
supervillin
chr19_+_6952319 0.59 ENSMUST00000070850.8
protein phosphatase 1, regulatory inhibitor subunit 14B
chr3_+_103875574 0.58 ENSMUST00000063717.14
ENSMUST00000055425.15
ENSMUST00000123611.8
ENSMUST00000090685.11
putative homeodomain transcription factor 1
chr11_+_102080489 0.58 ENSMUST00000078975.8
glucose 6 phosphatase, catalytic, 3
chr7_-_44518830 0.57 ENSMUST00000208682.2
prostate tumor over expressed gene 1
chr16_-_43800109 0.53 ENSMUST00000231700.2
zinc finger, DHHC domain containing 23
chr9_-_36637670 0.51 ENSMUST00000172702.9
ENSMUST00000172742.2
checkpoint kinase 1
chr17_+_73144531 0.50 ENSMUST00000233886.2
yippee like 5
chr2_-_120561983 0.48 ENSMUST00000110701.8
ENSMUST00000110700.2
congenital dyserythropoietic anemia, type I (human)
chr19_+_10502612 0.47 ENSMUST00000237321.2
ENSMUST00000038379.5
cleavage and polyadenylation specific factor 7
chr6_+_17306334 0.47 ENSMUST00000007799.13
ENSMUST00000115456.6
caveolin 1, caveolae protein
chr7_-_51511964 0.47 ENSMUST00000169357.2
Fanconi anemia, complementation group F
chr2_+_29956432 0.46 ENSMUST00000067996.7
SET nuclear oncogene
chr17_-_88105422 0.43 ENSMUST00000055221.9
potassium channel, subfamily K, member 12
chr11_+_74721733 0.38 ENSMUST00000000291.9
max binding protein
chr9_+_7184514 0.37 ENSMUST00000215683.2
ENSMUST00000034499.10
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr8_-_112660363 0.37 ENSMUST00000034429.9
transmembrane protein 231
chr13_-_114595122 0.35 ENSMUST00000231252.2
follistatin
chr9_+_66620959 0.34 ENSMUST00000071889.13
carbonic anhydrase 12
chr1_+_172309766 0.33 ENSMUST00000135267.8
ENSMUST00000052629.13
ENSMUST00000111235.8
immunoglobulin superfamily, member 9
chr1_-_30988381 0.33 ENSMUST00000232841.2
protein tyrosine phosphatase 4a1
chr9_+_66621001 0.33 ENSMUST00000085420.12
carbonic anhydrase 12
chr15_+_100513230 0.26 ENSMUST00000000356.10
DAZ associated protein 2
chr5_+_91079068 0.25 ENSMUST00000202781.2
ENSMUST00000071652.6
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr3_+_28835425 0.25 ENSMUST00000060500.9
eukaryotic translation initiation factor 5A2
chr5_-_124387812 0.25 ENSMUST00000162812.8
phosphatidylinositol transfer protein, membrane-associated 2
chr3_+_51391387 0.24 ENSMUST00000054387.8
RAB33B, member RAS oncogene family
chr9_+_119723931 0.21 ENSMUST00000036561.8
ENSMUST00000217472.2
ENSMUST00000215307.2
WD repeat domain 48
chr14_+_60872167 0.21 ENSMUST00000022566.14
ENSMUST00000159729.2
spermatogenesis associated 13
chr11_-_99742434 0.21 ENSMUST00000107437.2
keratin associated protein 4-16
chr4_+_101276893 0.21 ENSMUST00000131397.2
ENSMUST00000133055.8
adenylate kinase 4
chr10_+_127575407 0.20 ENSMUST00000054287.9
zinc finger and BTB domain containing 39
chr16_-_4376471 0.19 ENSMUST00000230875.2
transcription factor AP4
chr13_+_110531571 0.18 ENSMUST00000022212.9
polo like kinase 2
chr4_+_28813125 0.18 ENSMUST00000080934.11
ENSMUST00000029964.12
Eph receptor A7
chr13_+_58955675 0.18 ENSMUST00000224402.2
neurotrophic tyrosine kinase, receptor, type 2
chr17_+_34341766 0.17 ENSMUST00000042121.11
histocompatibility 2, class II, locus DMa
chr10_-_53506038 0.17 ENSMUST00000218549.3
minichromosome maintenance 9 homologous recombination repair factor
chr1_-_156767196 0.17 ENSMUST00000185198.7
Ral GEF with PH domain and SH3 binding motif 2
chr14_+_33041660 0.16 ENSMUST00000111955.2
Rho GTPase activating protein 22
chr2_+_31840340 0.16 ENSMUST00000148056.4
allograft inflammatory factor 1-like
chr4_-_126647156 0.15 ENSMUST00000030637.14
ENSMUST00000106116.2
neurochondrin
chr18_+_67422256 0.15 ENSMUST00000025403.8
inositol monophosphatase 2
chr4_+_28813152 0.14 ENSMUST00000108194.9
ENSMUST00000108191.2
Eph receptor A7
chr15_-_7427815 0.13 ENSMUST00000096494.5
EGF-like, fibronectin type III and laminin G domains
chr14_+_47120311 0.13 ENSMUST00000022386.15
ENSMUST00000228404.2
ENSMUST00000100672.11
sterile alpha motif domain containing 4
chr15_-_7427759 0.11 ENSMUST00000058593.10
EGF-like, fibronectin type III and laminin G domains
chr14_-_55163452 0.11 ENSMUST00000227037.2
embryonal Fyn-associated substrate
chr15_-_79212323 0.09 ENSMUST00000166977.9
phospholipase A2, group VI
chr13_+_58956077 0.08 ENSMUST00000109838.10
neurotrophic tyrosine kinase, receptor, type 2
chr3_+_103875261 0.08 ENSMUST00000117150.8
putative homeodomain transcription factor 1
chr5_+_125080504 0.07 ENSMUST00000197746.2
refilin A
chr8_-_111629074 0.06 ENSMUST00000041382.7
fucose kinase
chrX_+_80114242 0.06 ENSMUST00000171953.8
ENSMUST00000026760.3
transmembrane protein 47
chr15_-_79212400 0.06 ENSMUST00000173163.8
ENSMUST00000047816.15
ENSMUST00000172403.9
ENSMUST00000173632.8
phospholipase A2, group VI
chr1_+_82564627 0.06 ENSMUST00000113457.9
collagen, type IV, alpha 3
chr13_-_100969823 0.06 ENSMUST00000225922.2
solute carrier family 30 (zinc transporter), member 5
chr9_-_43017249 0.05 ENSMUST00000165665.9
Rho guanine nucleotide exchange factor (GEF) 12
chr11_+_118319319 0.04 ENSMUST00000017590.9
C1q and tumor necrosis factor related protein 1
chr5_-_88823049 0.04 ENSMUST00000133532.8
ENSMUST00000150438.2
G-rich RNA sequence binding factor 1
chr16_-_22475915 0.03 ENSMUST00000089925.10
diacylglycerol kinase, gamma
chr2_+_128809268 0.03 ENSMUST00000110320.9
ENSMUST00000110319.3
zinc finger CCCH type containing 6
chr17_+_5045178 0.01 ENSMUST00000092723.11
ENSMUST00000232180.2
ENSMUST00000115797.9
AT rich interactive domain 1B (SWI-like)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.3 4.0 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
1.0 6.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.7 3.3 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.6 4.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.5 1.6 GO:0006550 isoleucine catabolic process(GO:0006550)
0.5 2.9 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.5 1.4 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.4 1.2 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.4 3.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.4 2.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 2.5 GO:0048254 snoRNA localization(GO:0048254)
0.3 1.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.3 1.3 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.3 0.9 GO:0060166 olfactory pit development(GO:0060166)
0.3 4.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3 2.3 GO:0006561 proline biosynthetic process(GO:0006561)
0.3 1.1 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.2 3.5 GO:0030432 peristalsis(GO:0030432)
0.2 0.8 GO:1902477 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.2 1.4 GO:0070475 rRNA base methylation(GO:0070475)
0.2 1.7 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.2 3.1 GO:0006968 cellular defense response(GO:0006968)
0.2 2.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 3.4 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.2 0.8 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 0.9 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 1.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 2.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.3 GO:0035879 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 4.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 2.6 GO:0007614 short-term memory(GO:0007614)
0.1 1.7 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 3.7 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.1 1.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 4.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 2.4 GO:0006541 glutamine metabolic process(GO:0006541)
0.1 4.0 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 1.1 GO:0033129 positive regulation of histone phosphorylation(GO:0033129)
0.1 0.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.2 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.2 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 2.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 1.8 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 2.8 GO:0006414 translational elongation(GO:0006414)
0.0 1.6 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.8 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 3.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 4.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 2.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 1.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 1.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 2.0 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 1.5 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 1.3 GO:0051028 mRNA transport(GO:0051028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0031904 endosome lumen(GO:0031904)
0.6 1.9 GO:0034457 Mpp10 complex(GO:0034457)
0.5 3.3 GO:0071914 prominosome(GO:0071914)
0.4 4.0 GO:0042382 paraspeckles(GO:0042382)
0.4 2.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.3 2.2 GO:0005638 lamin filament(GO:0005638)
0.3 2.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 4.5 GO:0030061 mitochondrial crista(GO:0030061)
0.2 3.3 GO:0005652 nuclear lamina(GO:0005652)
0.2 1.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 1.5 GO:0032797 SMN complex(GO:0032797)
0.1 8.2 GO:0015030 Cajal body(GO:0015030)
0.1 2.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 2.0 GO:0000145 exocyst(GO:0000145)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 3.1 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.8 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.8 GO:0000346 transcription export complex(GO:0000346)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.7 GO:0016592 mediator complex(GO:0016592)
0.0 3.6 GO:0005581 collagen trimer(GO:0005581)
0.0 4.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 5.0 GO:0001650 fibrillar center(GO:0001650)
0.0 1.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 1.6 GO:0005643 nuclear pore(GO:0005643)
0.0 1.6 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 1.2 GO:0005657 replication fork(GO:0005657)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.9 2.6 GO:0097677 STAT family protein binding(GO:0097677)
0.8 4.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.6 2.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.6 2.4 GO:0003883 CTP synthase activity(GO:0003883)
0.6 3.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.6 2.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.5 1.5 GO:0030622 U4atac snRNA binding(GO:0030622)
0.5 1.4 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.5 2.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.5 2.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 1.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.4 2.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 3.1 GO:0016936 galactoside binding(GO:0016936)
0.3 1.7 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.3 3.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3 1.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 1.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 1.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 3.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 1.6 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.2 2.5 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.2 2.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 2.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 1.4 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 0.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 3.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 3.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.8 GO:0008823 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.2 GO:0048185 activin binding(GO:0048185)
0.1 0.8 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 3.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 3.3 GO:0042805 actinin binding(GO:0042805)
0.0 0.3 GO:0008046 GPI-linked ephrin receptor activity(GO:0005004) axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 3.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 4.3 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 3.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 3.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 3.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 3.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.0 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 2.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 8.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 4.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 6.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 2.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 4.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 1.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling