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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hivep1

Z-value: 0.96

Motif logo

Transcription factors associated with Hivep1

Gene Symbol Gene ID Gene Info
ENSMUSG00000021366.9 Hivep1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hivep1mm39_v1_chr13_+_42205790_42205880-0.105.7e-01Click!

Activity profile of Hivep1 motif

Sorted Z-values of Hivep1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hivep1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_46146558 3.17 ENSMUST00000121916.8
ENSMUST00000034586.9
apolipoprotein C-III
chr3_+_20039775 2.87 ENSMUST00000172860.2
ceruloplasmin
chr5_-_134776101 2.84 ENSMUST00000015138.13
elastin
chr17_-_35081456 2.81 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr10_-_95251327 2.63 ENSMUST00000172070.8
ENSMUST00000150432.8
suppressor of cytokine signaling 2
chr10_+_111342147 2.42 ENSMUST00000164773.2
pleckstrin homology like domain, family A, member 1
chr13_+_43938251 2.38 ENSMUST00000015540.4
CD83 antigen
chr9_-_46146928 2.28 ENSMUST00000118649.8
apolipoprotein C-III
chr10_-_95251145 2.18 ENSMUST00000119917.2
suppressor of cytokine signaling 2
chr17_+_43978377 2.17 ENSMUST00000233627.2
ENSMUST00000233437.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr5_+_90708962 2.11 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chr17_+_43978280 2.07 ENSMUST00000170988.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr7_-_99276310 1.99 ENSMUST00000178124.3
trophoblast glycoprotein-like
chr19_+_34268053 1.61 ENSMUST00000025691.13
Fas (TNF receptor superfamily member 6)
chr4_-_57916283 1.56 ENSMUST00000063816.6
RIKEN cDNA D630039A03 gene
chr11_+_78079562 1.53 ENSMUST00000108322.9
RAB34, member RAS oncogene family
chr19_+_34268071 1.47 ENSMUST00000112472.4
ENSMUST00000235232.2
Fas (TNF receptor superfamily member 6)
chr9_-_70841881 1.47 ENSMUST00000214995.2
lipase, hepatic
chr16_-_30086317 1.41 ENSMUST00000064856.9
carboxypeptidase N, polypeptide 2
chr17_+_35482063 1.39 ENSMUST00000172503.3
histocompatibility 2, D region locus 1
chr17_+_35598583 1.35 ENSMUST00000081435.5
histocompatibility 2, Q region locus 4
chr1_+_192835414 1.35 ENSMUST00000076521.7
interferon regulatory factor 6
chr17_-_28736483 1.35 ENSMUST00000114792.8
ENSMUST00000177939.8
FK506 binding protein 5
chr6_+_71176811 1.31 ENSMUST00000067492.8
fatty acid binding protein 1, liver
chr17_+_35481702 1.25 ENSMUST00000172785.8
histocompatibility 2, D region locus 1
chr14_+_55797934 1.25 ENSMUST00000121622.8
ENSMUST00000143431.2
ENSMUST00000150481.8
DDB1 and CUL4 associated factor 11
chr9_-_70842090 1.24 ENSMUST00000034731.10
lipase, hepatic
chr14_+_55798517 1.24 ENSMUST00000117701.8
DDB1 and CUL4 associated factor 11
chr6_-_21852508 1.22 ENSMUST00000031678.10
tetraspanin 12
chr14_+_55798362 1.22 ENSMUST00000072530.11
ENSMUST00000128490.9
DDB1 and CUL4 associated factor 11
chr4_+_138181616 1.15 ENSMUST00000050918.4
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr6_-_21851827 1.14 ENSMUST00000202353.2
ENSMUST00000134635.2
ENSMUST00000123116.8
ENSMUST00000120965.8
ENSMUST00000143531.2
tetraspanin 12
chr12_-_113561594 1.12 ENSMUST00000103444.3
immunoglobulin heavy variable 5-4
chr6_+_83034825 1.11 ENSMUST00000077502.5
DEAQ RNA-dependent ATPase
chr11_+_78079631 1.05 ENSMUST00000056241.12
ENSMUST00000207728.2
RAB34, member RAS oncogene family
chr12_-_55539372 0.97 ENSMUST00000021413.9
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr18_+_84106188 0.93 ENSMUST00000060223.4
zinc binding alcohol dehydrogenase, domain containing 2
chrX_-_161747552 0.92 ENSMUST00000038769.3
S100 calcium binding protein G
chr2_-_69172944 0.92 ENSMUST00000102709.8
ENSMUST00000102710.10
ENSMUST00000180142.2
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr5_-_92496730 0.91 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr7_-_19363280 0.90 ENSMUST00000094762.10
ENSMUST00000049912.15
ENSMUST00000098754.5
avian reticuloendotheliosis viral (v-rel) oncogene related B
chr4_-_133695264 0.90 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr11_+_78237492 0.86 ENSMUST00000100755.4
unc-119 lipid binding chaperone
chr3_-_132655954 0.80 ENSMUST00000042744.16
ENSMUST00000117811.8
nephronectin
chr17_-_34219225 0.79 ENSMUST00000238098.2
ENSMUST00000087189.7
ENSMUST00000173075.3
ENSMUST00000172912.8
ENSMUST00000236740.2
ENSMUST00000025181.18
histocompatibility 2, K1, K region
chr11_+_101066867 0.77 ENSMUST00000103109.4
contactin associated protein-like 1
chr19_+_38469504 0.76 ENSMUST00000182481.8
phospholipase C, epsilon 1
chr7_+_28466160 0.70 ENSMUST00000122915.8
ENSMUST00000072965.5
ENSMUST00000170068.9
sirtuin 2
chr18_+_84106796 0.69 ENSMUST00000235383.2
zinc binding alcohol dehydrogenase, domain containing 2
chr7_+_19222972 0.68 ENSMUST00000011407.8
exocyst complex component 3-like 2
chrX_+_35375751 0.68 ENSMUST00000033418.8
interleukin 13 receptor, alpha 1
chr17_+_35413415 0.66 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr17_+_45866618 0.66 ENSMUST00000024742.9
ENSMUST00000233929.2
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr5_-_144294854 0.66 ENSMUST00000055190.8
BAI1-associated protein 2-like 1
chr11_+_94102255 0.66 ENSMUST00000041589.6
transducer of ErbB-2.1
chr1_+_161796748 0.65 ENSMUST00000111594.3
ENSMUST00000028021.7
ENSMUST00000193784.2
ENSMUST00000161826.2
phosphatidylinositol glycan anchor biosynthesis, class C
predicted gene, 38304
chr12_-_113823290 0.60 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr12_-_113542610 0.60 ENSMUST00000195468.6
ENSMUST00000103442.3
immunoglobulin heavy variable 5-2
chr1_+_161796854 0.59 ENSMUST00000160881.2
ENSMUST00000159648.2
phosphatidylinositol glycan anchor biosynthesis, class C
chr11_+_70431063 0.58 ENSMUST00000018429.12
ENSMUST00000108557.10
ENSMUST00000108556.2
phospholipase D2
chr6_+_55313409 0.58 ENSMUST00000004774.4
aquaporin 1
chr1_-_36312482 0.57 ENSMUST00000056946.8
neuralized E3 ubiquitin protein ligase 3
chr5_+_137348423 0.56 ENSMUST00000111055.9
Eph receptor B4
chr2_-_5068807 0.55 ENSMUST00000114996.8
optineurin
chr18_-_20192535 0.54 ENSMUST00000075214.9
ENSMUST00000039247.11
desmocollin 2
chr5_-_144902598 0.53 ENSMUST00000110677.8
ENSMUST00000085684.11
ENSMUST00000100461.7
SMAD specific E3 ubiquitin protein ligase 1
chr5_-_116584765 0.52 ENSMUST00000139425.2
serine/arginine repetitive matrix 4
chr5_+_137348363 0.51 ENSMUST00000061244.15
Eph receptor B4
chr5_-_148489457 0.50 ENSMUST00000079324.14
ubiquitin-like 3
chr4_-_82423985 0.50 ENSMUST00000107245.9
ENSMUST00000107246.2
nuclear factor I/B
chr17_+_35780977 0.49 ENSMUST00000174525.8
ENSMUST00000068291.7
histocompatibility 2, Q region locus 10
chr11_+_75546989 0.48 ENSMUST00000136935.2
myosin IC
chr4_-_82423944 0.47 ENSMUST00000107248.8
ENSMUST00000107247.8
nuclear factor I/B
chr15_-_76501525 0.46 ENSMUST00000230977.2
solute carrier family 39 (zinc transporter), member 4
chr11_+_75546671 0.45 ENSMUST00000108431.3
myosin IC
chr10_-_27492827 0.45 ENSMUST00000092639.12
laminin, alpha 2
chr4_+_155646807 0.45 ENSMUST00000030939.14
NAD kinase
chr2_-_5068743 0.45 ENSMUST00000027986.5
optineurin
chr9_+_5308828 0.44 ENSMUST00000162846.8
ENSMUST00000027012.14
caspase 4, apoptosis-related cysteine peptidase
chr11_-_93846453 0.43 ENSMUST00000072566.5
NME/NM23 nucleoside diphosphate kinase 2
chr2_+_119803180 0.43 ENSMUST00000066058.8
mitogen-activated protein kinase binding protein 1
chr3_+_122277372 0.41 ENSMUST00000197073.2
breast cancer anti-estrogen resistance 3
chr16_-_18052937 0.41 ENSMUST00000076957.7
zinc finger, DHHC domain containing 8
chr15_-_89033761 0.40 ENSMUST00000088823.5
mitogen-activated protein kinase 11
chrX_-_7242065 0.40 ENSMUST00000191497.2
ENSMUST00000115744.2
ubiquitin specific peptidase 27, X chromosome
chr6_-_48817914 0.38 ENSMUST00000164733.4
transmembrane protein 176B
chr9_-_50679408 0.38 ENSMUST00000177546.8
ENSMUST00000176238.2
RIKEN cDNA 1110032A03 gene
chr17_+_56312672 0.37 ENSMUST00000133998.8
MPN domain containing
chr6_-_48818006 0.37 ENSMUST00000203229.3
transmembrane protein 176B
chr18_+_37822865 0.37 ENSMUST00000195112.2
protocadherin gamma subfamily B, 2
chr9_-_44646487 0.36 ENSMUST00000034611.15
pleckstrin homology like domain, family B, member 1
chr11_-_70120503 0.36 ENSMUST00000153449.2
ENSMUST00000000326.12
B cell CLL/lymphoma 6, member B
chr19_-_5821442 0.36 ENSMUST00000236978.2
SCY1-like 1 (S. cerevisiae)
chr6_-_48818044 0.35 ENSMUST00000101429.11
ENSMUST00000204073.3
transmembrane protein 176B
chr12_-_113912416 0.35 ENSMUST00000103464.3
immunoglobulin heavy variable 4-1
chr8_+_95472218 0.34 ENSMUST00000034231.4
chemokine (C-C motif) ligand 22
chr19_-_5135510 0.33 ENSMUST00000140389.8
ENSMUST00000151413.2
ENSMUST00000077066.8
transmembrane protein 151A
chr14_-_34225281 0.33 ENSMUST00000171343.9
bone morphogenetic protein receptor, type 1A
chr7_-_90106375 0.33 ENSMUST00000032844.7
transmembrane protein 126A
chr2_-_118377500 0.32 ENSMUST00000125860.3
BCL2 modifying factor
chr4_-_40239778 0.31 ENSMUST00000037907.13
DEAD/H box helicase 58
chr19_-_5821373 0.30 ENSMUST00000236297.2
ENSMUST00000236773.2
ENSMUST00000025890.10
SCY1-like 1 (S. cerevisiae)
chr6_-_48818302 0.30 ENSMUST00000203355.3
ENSMUST00000166247.8
transmembrane protein 176B
chr16_-_28571820 0.27 ENSMUST00000232352.2
fibroblast growth factor 12
chr19_+_6919229 0.27 ENSMUST00000025910.13
BCL2-associated agonist of cell death
chr6_-_8778439 0.26 ENSMUST00000115520.8
ENSMUST00000038403.12
ENSMUST00000115518.8
islet cell autoantigen 1
chrX_-_23151771 0.26 ENSMUST00000115319.9
kelch-like 13
chr2_+_32611067 0.25 ENSMUST00000074248.11
SH2 domain containing 3C
chr11_+_5738480 0.25 ENSMUST00000109845.8
ENSMUST00000020769.14
ENSMUST00000102928.5
drebrin-like
chr1_+_192984278 0.24 ENSMUST00000016315.16
laminin, beta 3
chr5_-_121975676 0.24 ENSMUST00000197892.3
SH2B adaptor protein 3
chr12_+_85871691 0.24 ENSMUST00000040273.14
ENSMUST00000110224.8
ENSMUST00000142411.9
tubulin tyrosine ligase-like family, member 5
chr12_+_111132779 0.24 ENSMUST00000117269.8
TNF receptor-associated factor 3
chr11_-_5492175 0.24 ENSMUST00000020776.5
coiled-coil domain containing 117
chrX_-_8072714 0.23 ENSMUST00000089403.10
ENSMUST00000077595.12
ENSMUST00000089402.10
ENSMUST00000082320.12
porcupine O-acyltransferase
chr7_-_28465870 0.22 ENSMUST00000085851.12
ENSMUST00000032815.11
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
chr12_+_111132847 0.20 ENSMUST00000021706.11
TNF receptor-associated factor 3
chr3_+_96508400 0.20 ENSMUST00000062058.5
Lix1-like
chr5_-_98178811 0.20 ENSMUST00000031281.14
anthrax toxin receptor 2
chr14_+_52222283 0.19 ENSMUST00000093813.12
ENSMUST00000100639.11
ENSMUST00000182909.8
ENSMUST00000182760.8
ENSMUST00000182061.8
ENSMUST00000182193.2
Rho guanine nucleotide exchange factor (GEF) 40
chr7_-_125799570 0.18 ENSMUST00000009344.16
exportin 6
chr11_-_100302700 0.18 ENSMUST00000141840.2
prolyl 3-hydroxylase family member 4 (non-enzymatic)
chr15_-_38299934 0.18 ENSMUST00000228772.2
Kruppel-like factor 10
chr4_+_126156118 0.17 ENSMUST00000030660.9
trafficking protein particle complex 3
chr6_-_83513222 0.16 ENSMUST00000075161.12
actin, gamma 2, smooth muscle, enteric
chr7_-_79492091 0.15 ENSMUST00000049004.8
alanyl (membrane) aminopeptidase
chr19_+_6919691 0.15 ENSMUST00000113426.8
ENSMUST00000238184.2
ENSMUST00000113423.10
ENSMUST00000237334.2
ENSMUST00000235240.2
BCL2-associated agonist of cell death
chr18_-_4352944 0.15 ENSMUST00000025078.10
mitogen-activated protein kinase kinase kinase 8
chr6_-_97464761 0.15 ENSMUST00000032146.14
FERM domain containing 4B
chr11_+_97697328 0.15 ENSMUST00000153520.3
LIM and SH3 protein 1
chr7_-_125799644 0.15 ENSMUST00000168189.8
exportin 6
chr13_-_100382831 0.14 ENSMUST00000049789.3
NLR family, apoptosis inhibitory protein 5
chr19_-_6919755 0.14 ENSMUST00000099782.10
G protein-coupled receptor 137
chr13_-_19521337 0.14 ENSMUST00000103563.3
T cell receptor gamma variable 2
chr14_-_70666513 0.12 ENSMUST00000226426.2
ENSMUST00000048129.6
piwi-like RNA-mediated gene silencing 2
chr6_-_8778106 0.12 ENSMUST00000151758.2
ENSMUST00000115519.8
ENSMUST00000153390.8
islet cell autoantigen 1
chr11_+_98851238 0.12 ENSMUST00000107473.3
retinoic acid receptor, alpha
chr5_-_98178834 0.11 ENSMUST00000199088.2
anthrax toxin receptor 2
chr12_+_111132908 0.11 ENSMUST00000139162.8
ENSMUST00000060274.7
TNF receptor-associated factor 3
chr18_-_39062201 0.10 ENSMUST00000134864.2
fibroblast growth factor 1
chr7_-_125799585 0.10 ENSMUST00000163959.2
exportin 6
chr11_-_23720953 0.09 ENSMUST00000102864.5
reticuloendotheliosis oncogene
chr19_+_42040681 0.08 ENSMUST00000164518.4
RIKEN cDNA 4933411K16 gene
chr7_+_27305222 0.08 ENSMUST00000143499.8
ENSMUST00000108343.8
thymoma viral proto-oncogene 2
chr15_+_76594810 0.08 ENSMUST00000136840.8
ENSMUST00000127208.8
ENSMUST00000036423.15
ENSMUST00000137649.8
ENSMUST00000155225.2
ENSMUST00000155735.2
leucine rich repeat containing 14
chr2_+_131792774 0.08 ENSMUST00000110170.8
ENSMUST00000110172.9
ENSMUST00000110171.9
prion like protein doppel
chr19_+_24853039 0.07 ENSMUST00000073080.7
predicted gene 10053
chr1_-_172418058 0.07 ENSMUST00000065679.8
SLAM family member 8
chr2_-_103133524 0.07 ENSMUST00000090475.10
ets homologous factor
chr12_+_36364136 0.07 ENSMUST00000041407.7
sclerostin domain containing 1
chr10_-_27492792 0.07 ENSMUST00000189575.2
laminin, alpha 2
chr7_+_27305271 0.06 ENSMUST00000051356.12
thymoma viral proto-oncogene 2
chrX_+_82898974 0.06 ENSMUST00000239269.2
dystrophin, muscular dystrophy
chr15_+_102379621 0.06 ENSMUST00000229918.2
poly(rC) binding protein 2
chr10_+_119828821 0.05 ENSMUST00000105261.9
glutamate receptor interacting protein 1
chr15_-_79048674 0.05 ENSMUST00000230261.2
ENSMUST00000040019.5
SRY (sex determining region Y)-box 10
chr15_+_102379503 0.05 ENSMUST00000229222.2
poly(rC) binding protein 2
chr11_-_99176086 0.05 ENSMUST00000017255.4
keratin 24
chr15_-_78090591 0.04 ENSMUST00000120592.2
parvalbumin
chr2_-_119377675 0.03 ENSMUST00000133668.2
exonuclease 3'-5' domain containing 1
chr10_+_127216459 0.03 ENSMUST00000166820.8
R3H domain containing 2
chr5_+_137059127 0.03 ENSMUST00000041543.9
ENSMUST00000186451.2
VGF nerve growth factor inducible
chr4_+_128777339 0.03 ENSMUST00000035667.9
tripartite motif-containing 62
chr4_-_40239700 0.02 ENSMUST00000142055.2
DEAD/H box helicase 58
chr2_-_103133503 0.02 ENSMUST00000111176.9
ets homologous factor
chr3_+_88857929 0.01 ENSMUST00000186583.7
ASH1 like histone lysine methyltransferase
chr12_+_98886826 0.01 ENSMUST00000085109.10
ENSMUST00000079146.13
tetratricopeptide repeat domain 8
chr10_-_81463631 0.01 ENSMUST00000042923.9
sirtuin 6
chr10_-_81463091 0.01 ENSMUST00000143424.2
ENSMUST00000119324.8
sirtuin 6
chr10_+_119828867 0.01 ENSMUST00000154238.8
glutamate receptor interacting protein 1
chr7_-_30371021 0.01 ENSMUST00000051495.7
PMIS2 transmembrane protein
chr4_-_120672900 0.01 ENSMUST00000120779.8
nuclear transcription factor-Y gamma
chr2_-_57004933 0.01 ENSMUST00000028166.9
nuclear receptor subfamily 4, group A, member 2
chr1_+_186947934 0.00 ENSMUST00000160471.8
G patch domain containing 2
chr18_-_34784746 0.00 ENSMUST00000025228.12
ENSMUST00000133181.2
CDC23 cell division cycle 23

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0030573 bile acid catabolic process(GO:0030573)
1.4 5.5 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
1.0 3.1 GO:0031104 dendrite regeneration(GO:0031104)
0.7 3.4 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.5 2.7 GO:0034371 chylomicron remodeling(GO:0034371)
0.5 2.6 GO:1905171 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.3 0.9 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.2 1.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.7 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.2 0.9 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.2 2.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 0.6 GO:0071288 cellular response to mercury ion(GO:0071288)
0.2 1.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 0.5 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.2 0.7 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.2 1.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 0.7 GO:0032329 serine transport(GO:0032329)
0.2 2.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.8 GO:0097195 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 1.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.4 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.1 0.9 GO:0046618 drug export(GO:0046618)
0.1 4.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.9 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.3 GO:0048352 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.1 1.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 0.3 GO:1904092 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.1 0.5 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 1.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.4 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.8 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 2.9 GO:0046688 response to copper ion(GO:0046688)
0.1 0.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.3 GO:0009597 detection of virus(GO:0009597)
0.1 0.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.5 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 2.4 GO:0010842 retina layer formation(GO:0010842)
0.1 0.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.7 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.1 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.4 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.9 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0000239 pachytene(GO:0000239)
0.0 0.9 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 1.1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.4 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.6 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
0.0 1.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0021627 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0021554 optic nerve development(GO:0021554)
0.0 2.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 2.8 GO:0030833 regulation of actin filament polymerization(GO:0030833)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0071953 elastic fiber(GO:0071953)
0.5 5.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.4 5.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 3.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 0.9 GO:0045160 myosin I complex(GO:0045160)
0.1 0.6 GO:0032127 dense core granule membrane(GO:0032127)
0.1 1.3 GO:0045179 apical cortex(GO:0045179)
0.1 0.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 3.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.7 GO:0033010 paranodal junction(GO:0033010)
0.1 1.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 2.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 2.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 2.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 6.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
1.4 5.5 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.8 4.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.8 3.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.5 2.7 GO:0035478 chylomicron binding(GO:0035478)
0.4 1.6 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.3 5.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 2.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 0.7 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 3.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.0 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 2.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 1.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0004673 protein histidine kinase activity(GO:0004673)
0.1 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0030346 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) protein phosphatase 2B binding(GO:0030346)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 2.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.1 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 5.4 ST GAQ PATHWAY G alpha q Pathway
0.0 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 3.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 8.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 2.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 3.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 3.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.0 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 3.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells