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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hmbox1

Z-value: 1.96

Motif logo

Transcription factors associated with Hmbox1

Gene Symbol Gene ID Gene Info
ENSMUSG00000021972.15 Hmbox1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hmbox1mm39_v1_chr14_-_65187287_65187335-0.077.0e-01Click!

Activity profile of Hmbox1 motif

Sorted Z-values of Hmbox1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmbox1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_39275518 21.14 ENSMUST00000003137.15
cytochrome P450, family 2, subfamily c, polypeptide 29
chr13_+_4484305 10.63 ENSMUST00000021630.15
aldo-keto reductase family 1, member C6
chr18_-_38999755 6.31 ENSMUST00000115582.8
ENSMUST00000236060.2
fibroblast growth factor 1
chr11_-_94932158 5.93 ENSMUST00000038431.8
pyruvate dehydrogenase kinase, isoenzyme 2
chr1_+_163979384 5.49 ENSMUST00000086040.6
coagulation factor V
chr15_+_54975713 4.94 ENSMUST00000096433.10
DEP domain containing MTOR-interacting protein
chr19_+_32573182 4.92 ENSMUST00000235594.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr18_-_10706701 4.84 ENSMUST00000002549.9
ENSMUST00000117726.9
ENSMUST00000117828.9
abhydrolase domain containing 3
chr18_-_3281089 4.79 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr18_-_39000056 4.70 ENSMUST00000236630.2
ENSMUST00000237356.2
fibroblast growth factor 1
chr5_+_87148697 4.54 ENSMUST00000031186.9
UDP glucuronosyltransferase 2 family, polypeptide B35
chr9_-_71075939 4.52 ENSMUST00000113570.8
aquaporin 9
chr1_+_21310803 4.43 ENSMUST00000027067.15
glutathione S-transferase, alpha 3
chr1_+_21310821 4.36 ENSMUST00000121676.8
ENSMUST00000124990.3
glutathione S-transferase, alpha 3
chr4_+_128887017 4.08 ENSMUST00000030583.13
ENSMUST00000102604.11
adenylate kinase 2
chr1_+_182591425 4.06 ENSMUST00000155229.7
ENSMUST00000153348.8
sushi domain containing 4
chr1_+_88128323 4.03 ENSMUST00000049289.9
UDP glucuronosyltransferase 1 family, polypeptide A2
chrM_+_5319 4.00 ENSMUST00000082402.1
mitochondrially encoded cytochrome c oxidase I
chr11_+_51654511 3.70 ENSMUST00000020653.6
secretion associated Ras related GTPase 1B
chr4_+_117109204 3.67 ENSMUST00000125943.8
ENSMUST00000106434.8
transmembrane protein 53
chr4_+_98919183 3.60 ENSMUST00000030280.7
angiopoietin-like 3
chr15_-_100576715 3.59 ENSMUST00000229869.2
chymotrypsin-like elastase family, member 1
chr8_+_45960804 3.53 ENSMUST00000067065.14
ENSMUST00000124544.8
ENSMUST00000138049.9
ENSMUST00000132139.9
sorbin and SH3 domain containing 2
chr11_-_88742285 3.53 ENSMUST00000107903.8
A kinase (PRKA) anchor protein 1
chr10_-_95159933 3.44 ENSMUST00000053594.7
CASP2 and RIPK1 domain containing adaptor with death domain
chr15_+_54975814 3.28 ENSMUST00000100660.11
DEP domain containing MTOR-interacting protein
chr8_+_46111703 3.04 ENSMUST00000134675.8
ENSMUST00000139869.8
ENSMUST00000126067.8
sorbin and SH3 domain containing 2
chr17_+_41245569 2.99 ENSMUST00000169611.4
methylmalonyl-Coenzyme A mutase
chr4_+_20042045 2.93 ENSMUST00000098242.4
gamma-glutamyl hydrolase
chr1_+_52884172 2.92 ENSMUST00000159352.8
ENSMUST00000044478.7
3-hydroxyisobutyryl-Coenzyme A hydrolase
chr2_-_12424212 2.84 ENSMUST00000124603.8
ENSMUST00000129993.3
ENSMUST00000028105.13
MINDY lysine 48 deubiquitinase 3
chr9_+_119170360 2.83 ENSMUST00000039784.12
acetyl-Coenzyme A acyltransferase 1A
chr7_-_44711075 2.81 ENSMUST00000007981.9
ENSMUST00000210500.2
ENSMUST00000210493.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr15_+_99291491 2.72 ENSMUST00000159531.3
transmembrane BAX inhibitor motif containing 6
chr11_+_101358990 2.66 ENSMUST00000001347.7
Rho family GTPase 2
chr8_+_45960931 2.52 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chr10_-_81243475 2.51 ENSMUST00000140916.8
nuclear factor I/C
chr11_+_93886906 2.48 ENSMUST00000041956.14
sperm associated antigen 9
chr7_-_44711130 2.46 ENSMUST00000211337.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr2_+_34764408 2.44 ENSMUST00000113068.9
ENSMUST00000047447.13
cutA divalent cation tolerance homolog-like
chr14_+_27344385 2.40 ENSMUST00000210135.2
ENSMUST00000090302.6
ENSMUST00000211087.2
ELKS/RAB6-interacting/CAST family member 2
chr14_+_66872699 2.38 ENSMUST00000159365.8
ENSMUST00000054661.8
ENSMUST00000225182.2
ENSMUST00000159068.2
adrenergic receptor, alpha 1a
chr4_+_100336003 2.24 ENSMUST00000133493.9
ENSMUST00000092730.5
ubiquitin-conjugating enzyme E2U (putative)
chr4_+_152423344 2.23 ENSMUST00000005175.5
chromodomain helicase DNA binding protein 5
chr10_+_20024203 2.19 ENSMUST00000020173.16
microtubule-associated protein 7
chr3_+_108561247 2.08 ENSMUST00000124384.8
ENSMUST00000029483.15
chloride channel CLIC-like 1
chr18_-_3280999 2.07 ENSMUST00000049942.13
cAMP responsive element modulator
chr2_+_34764496 2.06 ENSMUST00000028228.6
cutA divalent cation tolerance homolog-like
chr4_-_141450710 2.02 ENSMUST00000102484.5
ENSMUST00000177592.2
DNA-damage inducible protein 2
chr11_-_78313043 1.99 ENSMUST00000001122.6
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr4_-_133066549 1.95 ENSMUST00000105906.2
WD and tetratricopeptide repeats 1
chr3_+_108561223 1.93 ENSMUST00000106609.8
chloride channel CLIC-like 1
chr13_+_47347301 1.92 ENSMUST00000110111.4
ring finger protein 144B
chr4_-_133066594 1.88 ENSMUST00000043305.14
WD and tetratricopeptide repeats 1
chr4_+_116414855 1.87 ENSMUST00000030460.15
GC-rich promoter binding protein 1-like 1
chr12_+_65012564 1.86 ENSMUST00000066296.9
ENSMUST00000223166.2
TOG array regulator of axonemal microtubules 1
chr3_+_108561294 1.82 ENSMUST00000106613.2
chloride channel CLIC-like 1
chr4_+_116415251 1.81 ENSMUST00000106475.2
GC-rich promoter binding protein 1-like 1
chr12_-_65012270 1.80 ENSMUST00000222508.2
kelch-like 28
chr4_+_149602673 1.80 ENSMUST00000030839.13
catenin beta interacting protein 1
chr1_-_185849448 1.74 ENSMUST00000045388.8
lysophospholipase-like 1
chr12_-_81579614 1.71 ENSMUST00000169158.2
ENSMUST00000164431.2
ENSMUST00000163402.8
ENSMUST00000166664.2
ENSMUST00000164386.8
synaptojanin 2 binding protein
predicted gene 20498
chr16_-_43836681 1.71 ENSMUST00000036174.10
GRAM domain containing 1C
chr11_-_73067828 1.54 ENSMUST00000108480.2
ENSMUST00000054952.4
ER membrane protein complex subunit 6
chr17_+_74645936 1.51 ENSMUST00000224711.2
ENSMUST00000024869.8
ENSMUST00000233611.2
spastin
chr18_+_35695339 1.47 ENSMUST00000237365.2
matrin 3
chr3_+_28752050 1.44 ENSMUST00000029240.14
solute carrier family 2 (facilitated glucose transporter), member 2
chr8_-_106863423 1.42 ENSMUST00000146940.2
epithelial splicing regulatory protein 2
chr8_-_106863521 1.41 ENSMUST00000115979.9
epithelial splicing regulatory protein 2
chr4_-_58912678 1.40 ENSMUST00000144512.8
ENSMUST00000102889.10
ENSMUST00000055822.15
Ecm29 proteasome adaptor and scaffold
chr9_+_7445822 1.25 ENSMUST00000034497.8
matrix metallopeptidase 3
chr8_-_94739469 1.25 ENSMUST00000053766.14
autocrine motility factor receptor
chr10_-_40133558 1.24 ENSMUST00000216847.2
ENSMUST00000213628.2
ENSMUST00000217537.2
ENSMUST00000019982.9
general transcription factor IIIC, polypeptide 6, alpha
chr2_+_3771709 1.14 ENSMUST00000177037.2
family with sequence similarity 107, member B
chr4_+_152423075 1.12 ENSMUST00000030775.12
ENSMUST00000164662.8
chromodomain helicase DNA binding protein 5
chr4_-_155170738 1.10 ENSMUST00000030914.4
retention in endoplasmic reticulum sorting receptor 1
chr3_-_79749949 1.09 ENSMUST00000029568.7
transmembrane protein 144
chr1_-_16590244 1.09 ENSMUST00000144138.4
ENSMUST00000145092.8
ENSMUST00000131257.9
ENSMUST00000153966.9
ENSMUST00000162435.8
staufen double-stranded RNA binding protein 2
chr10_-_12743915 1.09 ENSMUST00000219584.2
utrophin
chr18_+_35695736 1.02 ENSMUST00000235851.2
ENSMUST00000235581.2
matrin 3
chr14_-_36628263 1.02 ENSMUST00000183007.2
coiled-coil serine rich 2
chr13_-_34261975 1.00 ENSMUST00000056427.10
tubulin, beta 2A class IIA
chr5_+_104318542 0.99 ENSMUST00000112771.2
dentin sialophosphoprotein
chr1_-_131207279 0.92 ENSMUST00000062108.10
inhibitor of kappaB kinase epsilon
chr3_-_95125051 0.92 ENSMUST00000107204.8
GA repeat binding protein, beta 2
chr3_+_132335704 0.91 ENSMUST00000212594.2
GIMAP family P-loop NTPase domain containing 1
chr19_-_28945194 0.91 ENSMUST00000162110.8
spermatogenesis associated 6 like
chr12_+_69939879 0.89 ENSMUST00000021466.10
atlastin GTPase 1
chr17_-_13070780 0.84 ENSMUST00000162389.2
ENSMUST00000162119.8
ENSMUST00000159223.8
MAS1 oncogene
chr19_-_32080496 0.83 ENSMUST00000235213.2
ENSMUST00000236504.2
N-acylsphingosine amidohydrolase 2
chr10_+_129072073 0.82 ENSMUST00000203248.3
olfactory receptor 774
chr12_+_103524690 0.82 ENSMUST00000187155.7
protein phosphatase 4, regulatory subunit 4
chr1_+_192855776 0.82 ENSMUST00000161235.3
ENSMUST00000160077.2
ENSMUST00000178744.2
ENSMUST00000192189.2
ENSMUST00000110831.4
ENSMUST00000191613.2
RIKEN cDNA A130010J15 gene
chr2_+_20742115 0.81 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr16_-_48592319 0.80 ENSMUST00000239408.2
T cell receptor associated transmembrane adaptor 1
chr3_-_108797306 0.77 ENSMUST00000102620.10
fibronectin type III domain containing 7
chr8_+_45960855 0.76 ENSMUST00000141039.8
sorbin and SH3 domain containing 2
chr1_+_192856044 0.75 ENSMUST00000193307.2
RIKEN cDNA A130010J15 gene
chr8_+_46111778 0.73 ENSMUST00000143820.8
sorbin and SH3 domain containing 2
chr3_-_57202301 0.72 ENSMUST00000171384.8
transmembrane 4 superfamily member 1
chr12_+_52144511 0.72 ENSMUST00000040090.16
nucleotide binding protein-like
chr14_+_56208885 0.72 ENSMUST00000089555.3
chymase 2, mast cell
chr2_+_70339175 0.71 ENSMUST00000134607.8
glutamate rich 2
chr7_+_7174315 0.71 ENSMUST00000051435.8
zinc finger protein 418
chr14_-_55909314 0.68 ENSMUST00000163750.8
neural precursor cell expressed, developmentally down-regulated gene 8
chr2_+_70339157 0.68 ENSMUST00000100041.9
glutamate rich 2
chr16_-_48592372 0.68 ENSMUST00000231701.3
T cell receptor associated transmembrane adaptor 1
chr15_-_37004302 0.67 ENSMUST00000228275.2
zinc finger protein 706
chr13_-_96678844 0.63 ENSMUST00000223475.2
polymerase (DNA directed), kappa
chr2_-_130126339 0.59 ENSMUST00000239288.2
ENSMUST00000028892.11
isocitrate dehydrogenase 3 (NAD+) beta
chr13_-_104953370 0.58 ENSMUST00000022228.13
CWC27 spliceosome-associated protein
chr5_+_136721938 0.58 ENSMUST00000196068.5
ENSMUST00000005611.10
myosin, light chain 10, regulatory
chr15_+_25774070 0.57 ENSMUST00000125667.3
myosin X
chr9_-_49397508 0.56 ENSMUST00000055096.5
tetratricopeptide repeat domain 12
chr14_+_53491504 0.54 ENSMUST00000103622.3
T cell receptor alpha variable 13N-2
chr4_+_85123358 0.54 ENSMUST00000107188.10
SH3-domain GRB2-like 2
chr3_+_144824644 0.52 ENSMUST00000199124.5
outer dense fiber of sperm tails 2-like
chr10_-_40134104 0.51 ENSMUST00000217141.2
general transcription factor IIIC, polypeptide 6, alpha
chr2_+_173561208 0.51 ENSMUST00000073081.6
RIKEN cDNA 1700010B08 gene
chr10_+_112107026 0.51 ENSMUST00000219301.2
ENSMUST00000092175.4
potassium voltage gated channel, Shaw-related subfamily, member 2
chr9_+_86349207 0.51 ENSMUST00000190957.7
DOP1 leucine zipper like protein A
chr12_-_113324852 0.49 ENSMUST00000223179.2
ENSMUST00000103423.3
Immunoglobulin heavy constant gamma 3
chr2_+_146854916 0.49 ENSMUST00000028921.6
5'-3' exoribonuclease 2
chr18_+_35695485 0.49 ENSMUST00000235199.2
ENSMUST00000237744.2
ENSMUST00000236276.2
matrin 3
chr14_+_53491249 0.49 ENSMUST00000196941.2
T cell receptor alpha variable 13N-2
chr3_-_104960264 0.48 ENSMUST00000098763.7
ENSMUST00000197437.5
CTTNBP2 N-terminal like
chr5_+_7354130 0.47 ENSMUST00000160634.2
ENSMUST00000159546.2
testis expressed 47
chr3_+_144824325 0.46 ENSMUST00000098538.9
ENSMUST00000106192.9
ENSMUST00000098539.7
ENSMUST00000029920.15
outer dense fiber of sperm tails 2-like
chr7_-_109322993 0.45 ENSMUST00000106735.9
ENSMUST00000033334.5
cDNA sequence BC051019
chr18_+_37433852 0.45 ENSMUST00000051754.2
protocadherin beta 3
chr7_-_79036222 0.44 ENSMUST00000205638.2
ENSMUST00000206320.3
ENSMUST00000205442.2
retinaldehyde binding protein 1
chr16_+_35803794 0.43 ENSMUST00000173555.8
karyopherin (importin) alpha 1
chr2_+_119039456 0.43 ENSMUST00000102519.5
zinc finger, FYVE domain containing 19
chr7_-_106354591 0.43 ENSMUST00000214306.2
ENSMUST00000216255.2
olfactory receptor 698
chr19_+_47854249 0.43 ENSMUST00000238084.2
glutathione S-transferase omega 2
chr4_-_148021217 0.39 ENSMUST00000019199.14
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr13_+_55359598 0.39 ENSMUST00000224918.2
nuclear receptor-binding SET-domain protein 1
chr3_-_95125190 0.39 ENSMUST00000136139.8
GA repeat binding protein, beta 2
chr10_-_10956700 0.39 ENSMUST00000105560.2
glutamate receptor, metabotropic 1
chr3_-_108797022 0.38 ENSMUST00000180063.8
ENSMUST00000053065.8
fibronectin type III domain containing 7
chr1_+_155916655 0.37 ENSMUST00000065648.15
ENSMUST00000097526.3
torsin A interacting protein 2
chr19_-_3332955 0.37 ENSMUST00000119292.8
ENSMUST00000025751.11
immunoglobulin mu binding protein 2
chr19_-_4977997 0.36 ENSMUST00000236758.2
dipeptidylpeptidase 3
chr8_+_110806390 0.35 ENSMUST00000212754.2
ENSMUST00000058804.10
zinc finger protein 612
chr2_+_70339832 0.35 ENSMUST00000153121.2
glutamate rich 2
chr10_-_128885867 0.35 ENSMUST00000216460.2
olfactory receptor 765
chr13_-_12535236 0.35 ENSMUST00000179308.3
EDAR (ectodysplasin-A receptor)-associated death domain
chr9_+_18848418 0.34 ENSMUST00000218385.2
olfactory receptor 832
chrX_-_23132991 0.33 ENSMUST00000115316.9
kelch-like 13
chr8_-_91544021 0.32 ENSMUST00000209208.2
predicted gene, 19935
chr10_-_128640232 0.31 ENSMUST00000051011.14
transmembrane protein 198b
chr1_-_22845124 0.29 ENSMUST00000115273.10
regulating synaptic membrane exocytosis 1
chr16_+_3408906 0.27 ENSMUST00000216259.2
olfactory receptor 161
chr14_-_10185787 0.27 ENSMUST00000225871.2
predicted gene, 49355
chr1_+_24216691 0.27 ENSMUST00000054588.15
collagen, type IX, alpha 1
chr17_+_35055962 0.26 ENSMUST00000173874.8
ENSMUST00000180043.8
ENSMUST00000046244.15
decapping exoribonuclease
chr1_-_133589020 0.26 ENSMUST00000193504.6
ENSMUST00000195067.2
ENSMUST00000191896.6
ENSMUST00000194668.6
ENSMUST00000195424.6
ENSMUST00000179598.4
ENSMUST00000027736.13
zinc finger CCCH type containing 11A
predicted gene, 38394
zinc finger CCCH type containing 11A
chr3_-_95125002 0.25 ENSMUST00000107209.8
GA repeat binding protein, beta 2
chr9_+_104443876 0.25 ENSMUST00000157006.8
copine IV
chrX_-_110447644 0.23 ENSMUST00000132319.8
ENSMUST00000123951.8
ribosomal protein S6 kinase polypeptide 6
chr11_+_96909559 0.21 ENSMUST00000107622.2
trans-acting transcription factor 6
chr2_-_171885386 0.20 ENSMUST00000087950.4
cerebellin 4 precursor protein
chr13_-_3943556 0.19 ENSMUST00000099946.6
neuroepithelial cell transforming gene 1
chr15_+_82152994 0.19 ENSMUST00000238416.3
ENSMUST00000239048.2
septin 3
chr3_-_68911886 0.19 ENSMUST00000169064.8
intraflagellar transport 80
chr17_+_69746321 0.18 ENSMUST00000169935.2
A kinase (PRKA) anchor inhibitor 1
chr5_-_70999547 0.18 ENSMUST00000199705.2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr14_+_54198389 0.16 ENSMUST00000103678.4
T cell receptor delta variable 2-2
chr5_-_143963413 0.15 ENSMUST00000031622.13
oncomodulin
chr2_+_96148418 0.15 ENSMUST00000135431.8
ENSMUST00000162807.9
leucine rich repeat containing 4C
chr11_+_22958338 0.12 ENSMUST00000172602.9
family with sequence similarity 161, member A
chr19_+_45003304 0.11 ENSMUST00000039016.14
leucine zipper, putative tumor suppressor 2
chr6_+_30610973 0.11 ENSMUST00000062758.11
carboxypeptidase A5
chr1_-_31261678 0.11 ENSMUST00000187892.8
ENSMUST00000233331.2
RIKEN cDNA 4931428L18 gene
chr18_+_65831324 0.10 ENSMUST00000115097.8
ENSMUST00000117694.2
ENSMUST00000235962.2
O-acyltransferase like
chr14_-_70561231 0.10 ENSMUST00000151011.8
solute carrier family 39 (zinc transporter), member 14
chrX_-_110440860 0.10 ENSMUST00000128819.8
ribosomal protein S6 kinase polypeptide 6
chr6_+_30611028 0.08 ENSMUST00000115138.8
carboxypeptidase A5
chr4_+_107747010 0.07 ENSMUST00000135454.8
ENSMUST00000106726.10
ENSMUST00000106727.10
ENSMUST00000119394.8
ENSMUST00000120473.8
ENSMUST00000125107.8
ENSMUST00000128474.2
CXXC motif containing zinc binding protein
chr6_-_97156032 0.07 ENSMUST00000095664.6
TATA element modulatory factor 1
chr13_+_49658249 0.05 ENSMUST00000051504.8
extracellular matrix protein 2, female organ and adipocyte specific
chr6_-_69678271 0.05 ENSMUST00000103363.2
immunoglobulin kappa variable 4-50
chr11_+_73068063 0.04 ENSMUST00000108477.2
Tax1 (human T cell leukemia virus type I) binding protein 3
chr14_+_53941464 0.04 ENSMUST00000103664.6
T cell receptor alpha variable 5-4
chr11_+_73489420 0.04 ENSMUST00000214228.2
olfactory receptor 384
chr14_-_79461316 0.04 ENSMUST00000040802.5
zinc finger protein 957
chr10_-_128918779 0.03 ENSMUST00000213579.2
olfactory receptor 767
chr11_-_49005701 0.03 ENSMUST00000060398.3
ENSMUST00000215553.2
ENSMUST00000109201.2
olfactory receptor 1396
chr11_+_73067909 0.03 ENSMUST00000040687.12
Tax1 (human T cell leukemia virus type I) binding protein 3
chr10_+_129084281 0.03 ENSMUST00000214109.2
olfactory receptor 775
chr6_-_68732577 0.02 ENSMUST00000103332.2
immunoglobulin kappa variable 4-92
chr3_+_93227047 0.01 ENSMUST00000090856.10
ENSMUST00000093774.4
hornerin
chr3_-_64049349 0.01 ENSMUST00000177151.9
vomeronasal 2, receptor 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
2.9 8.8 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377)
1.6 11.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
1.5 5.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
1.2 4.9 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.1 4.5 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
1.0 4.1 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.8 2.4 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.7 2.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.7 4.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.6 20.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.6 3.6 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.5 2.7 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.5 3.6 GO:0060309 elastin catabolic process(GO:0060309)
0.4 3.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.4 3.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.4 8.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.3 4.0 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.3 1.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.3 2.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.3 1.8 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.3 1.7 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.3 1.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 1.1 GO:0098963 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.3 1.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 4.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 1.5 GO:0051013 microtubule severing(GO:0051013)
0.2 0.8 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.2 3.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 3.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 0.5 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 10.6 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.1 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 2.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.4 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 2.9 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 1.7 GO:0007028 cytoplasm organization(GO:0007028)
0.1 9.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 4.8 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 1.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 2.8 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 0.4 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.1 0.6 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 2.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.6 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.4 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 2.8 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.7 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.2 GO:1902336 positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.0 0.8 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 1.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.9 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 5.5 GO:0006821 chloride transport(GO:0006821)
0.0 2.6 GO:0003170 heart valve development(GO:0003170)
0.0 2.0 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.9 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 2.5 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.0 0.7 GO:0045116 protein neddylation(GO:0045116)
0.0 0.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 1.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0003417 growth plate cartilage development(GO:0003417)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.7 4.1 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.3 2.2 GO:0033503 HULC complex(GO:0033503)
0.2 1.5 GO:1903349 omegasome membrane(GO:1903349)
0.2 4.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 3.5 GO:0030061 mitochondrial crista(GO:0030061)
0.2 5.5 GO:0031091 platelet alpha granule(GO:0031091)
0.2 1.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 3.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 6.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 2.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.3 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.1 1.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 2.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 12.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 3.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.4 GO:0030315 T-tubule(GO:0030315)
0.0 6.8 GO:0005769 early endosome(GO:0005769)
0.0 8.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 2.9 GO:0001650 fibrillar center(GO:0001650)
0.0 2.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.8 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 1.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.0 6.4 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
3.5 21.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.5 5.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.2 4.9 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.9 2.8 GO:0008775 acetate CoA-transferase activity(GO:0008775)
0.9 4.5 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.8 3.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.8 4.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.6 2.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.5 11.0 GO:0044548 S100 protein binding(GO:0044548)
0.5 2.8 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.5 2.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.4 3.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.3 4.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 1.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
0.3 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 3.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 8.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 3.4 GO:0070513 death domain binding(GO:0070513)
0.2 0.5 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 2.9 GO:0008242 omega peptidase activity(GO:0008242)
0.2 9.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 0.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 4.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.5 GO:0048273 MAP-kinase scaffold activity(GO:0005078) mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.4 GO:0099530 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.4 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.1 10.0 GO:0005507 copper ion binding(GO:0005507)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.8 GO:0001595 angiotensin receptor activity(GO:0001595)
0.1 0.8 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 2.9 GO:0016289 CoA hydrolase activity(GO:0016289)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 5.5 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 8.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 6.9 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 3.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.1 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 2.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 6.7 GO:0005525 GTP binding(GO:0005525)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 10.3 GO:0019904 protein domain specific binding(GO:0019904)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 11.0 PID FGF PATHWAY FGF signaling pathway
0.1 8.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 3.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 3.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.5 5.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 4.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 5.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 4.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 3.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 9.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 4.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 3.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism