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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hoxb1

Z-value: 1.06

Motif logo

Transcription factors associated with Hoxb1

Gene Symbol Gene ID Gene Info
ENSMUSG00000018973.3 Hoxb1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb1mm39_v1_chr11_+_96256565_96256578-0.281.0e-01Click!

Activity profile of Hoxb1 motif

Sorted Z-values of Hoxb1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_97066937 5.77 ENSMUST00000043077.8
thyroid hormone responsive
chr7_+_123061535 2.27 ENSMUST00000098056.6
aquaporin 8
chr7_+_123061497 2.25 ENSMUST00000033023.10
aquaporin 8
chr4_+_118285275 1.64 ENSMUST00000006557.13
ENSMUST00000167636.8
ENSMUST00000102673.11
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr18_-_56695333 1.30 ENSMUST00000066208.13
ENSMUST00000172734.8
aldehyde dehydrogenase family 7, member A1
chr6_-_124441731 1.19 ENSMUST00000008297.5
calsyntenin 3
chr18_-_56695259 1.07 ENSMUST00000171844.3
aldehyde dehydrogenase family 7, member A1
chr18_-_56695288 0.98 ENSMUST00000170309.8
aldehyde dehydrogenase family 7, member A1
chr15_+_74388044 0.93 ENSMUST00000042035.16
adhesion G protein-coupled receptor B1
chr11_-_97913420 0.92 ENSMUST00000103144.10
ENSMUST00000017552.13
ENSMUST00000092736.11
ENSMUST00000107562.2
calcium channel, voltage-dependent, beta 1 subunit
chr5_+_42225303 0.74 ENSMUST00000087332.5
predicted gene 16223
chr7_+_100970910 0.70 ENSMUST00000174291.8
ENSMUST00000167888.9
ENSMUST00000172662.2
START domain containing 10
chr14_+_70314652 0.69 ENSMUST00000035908.3
early growth response 3
chr10_-_33500583 0.69 ENSMUST00000161692.2
ENSMUST00000160299.2
ENSMUST00000019920.13
clavesin 2
chr7_+_100971034 0.66 ENSMUST00000173270.8
START domain containing 10
chr13_-_21685588 0.65 ENSMUST00000044043.3
cytochrome c oxidase subunit 5B, pseudogene
chr4_-_102971434 0.64 ENSMUST00000036557.15
ENSMUST00000036451.15
dynein axonemal intermediate chain 4
chr4_-_102971752 0.63 ENSMUST00000106868.4
dynein axonemal intermediate chain 4
chrX_+_109857866 0.62 ENSMUST00000078229.5
POU domain, class 3, transcription factor 4
chr10_-_67120959 0.60 ENSMUST00000159002.2
ENSMUST00000077839.13
nuclear receptor binding factor 2
chr11_+_76563281 0.58 ENSMUST00000056184.2
basic helix-loop-helix family, member a9
chr11_+_96256565 0.56 ENSMUST00000019117.3
homeobox B1
chr4_+_102971909 0.55 ENSMUST00000143417.8
MEIR1 treanscription regulator
chr11_+_98277276 0.48 ENSMUST00000041301.8
phenylethanolamine-N-methyltransferase
chr17_+_34866160 0.47 ENSMUST00000173984.2
activating transcription factor 6 beta
chr17_+_34866090 0.45 ENSMUST00000015605.15
activating transcription factor 6 beta
chr4_-_91288221 0.45 ENSMUST00000102799.10
ELAV like RNA binding protein 1
chr9_-_91247831 0.45 ENSMUST00000065360.5
zinc finger protein of the cerebellum 1
chr9_-_91247809 0.45 ENSMUST00000034927.13
zinc finger protein of the cerebellum 1
chr9_+_78303059 0.44 ENSMUST00000113367.2
DEAD box helicase 43
chr1_+_153541020 0.44 ENSMUST00000152114.8
ENSMUST00000111812.8
regulator of G-protein signaling 8
chr11_-_40646090 0.43 ENSMUST00000020576.8
cyclin G1
chr3_-_58433313 0.42 ENSMUST00000029385.9
stress-associated endoplasmic reticulum protein 1
chr6_-_93889483 0.41 ENSMUST00000205116.3
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr3_+_127426783 0.41 ENSMUST00000029587.9
neurogenin 2
chr7_+_73040908 0.40 ENSMUST00000128471.2
ENSMUST00000139780.3
repulsive guidance molecule family member A
chrX_+_104807868 0.40 ENSMUST00000033581.4
fibroblast growth factor 16
chr1_-_9770434 0.40 ENSMUST00000088658.11
myeloblastosis oncogene-like 1
chr2_+_65676111 0.40 ENSMUST00000122912.8
cysteine-serine-rich nuclear protein 3
chr10_-_88440869 0.39 ENSMUST00000119185.8
ENSMUST00000238199.2
myosin binding protein C, slow-type
chr1_-_25868788 0.38 ENSMUST00000151309.8
adhesion G protein-coupled receptor B3
chr14_-_24054352 0.37 ENSMUST00000190339.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_+_20112500 0.36 ENSMUST00000101558.10
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_65676176 0.35 ENSMUST00000053910.10
cysteine-serine-rich nuclear protein 3
chr10_+_36383008 0.33 ENSMUST00000168572.8
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chrX_+_142301666 0.33 ENSMUST00000134402.8
p21 (RAC1) activated kinase 3
chr8_-_117809188 0.33 ENSMUST00000109093.9
ENSMUST00000098375.6
polycystic kidney disease 1 like 2
chr1_-_25868592 0.32 ENSMUST00000135518.8
adhesion G protein-coupled receptor B3
chr14_-_24054273 0.31 ENSMUST00000188285.7
ENSMUST00000190044.7
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr9_+_108660989 0.30 ENSMUST00000192307.6
ENSMUST00000193560.6
ENSMUST00000194875.6
inositol hexaphosphate kinase 2
chr16_+_25620652 0.30 ENSMUST00000115304.8
ENSMUST00000115305.2
ENSMUST00000040231.13
ENSMUST00000115306.8
transformation related protein 63
chr18_+_66006119 0.29 ENSMUST00000025395.10
gastrin releasing peptide
chr14_-_24054186 0.29 ENSMUST00000188991.7
ENSMUST00000224468.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr15_-_95426419 0.29 ENSMUST00000229933.2
ENSMUST00000166170.9
NEL-like 2
chr17_+_27160203 0.29 ENSMUST00000194598.6
synaptic Ras GTPase activating protein 1 homolog (rat)
chr16_-_97763780 0.29 ENSMUST00000232187.2
ENSMUST00000231263.2
ENSMUST00000052089.9
ENSMUST00000063605.15
ENSMUST00000113734.9
ENSMUST00000231560.2
ENSMUST00000232165.2
zinc finger and BTB domain containing 21
C2 calcium-dependent domain containing 2
chr19_-_43376794 0.27 ENSMUST00000099428.5
heparanase 2
chr14_-_24053994 0.27 ENSMUST00000225431.2
ENSMUST00000188210.8
ENSMUST00000224787.2
ENSMUST00000225315.2
ENSMUST00000225556.2
ENSMUST00000223727.2
ENSMUST00000223655.2
ENSMUST00000224077.2
ENSMUST00000224812.2
ENSMUST00000224285.2
ENSMUST00000225471.2
ENSMUST00000224232.2
ENSMUST00000223749.2
ENSMUST00000224025.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_+_142359099 0.27 ENSMUST00000126521.9
ENSMUST00000211094.2
spexin hormone
chr11_-_69439934 0.26 ENSMUST00000108659.2
dynein, axonemal, heavy chain 2
chr3_-_37286714 0.25 ENSMUST00000161015.2
ENSMUST00000029273.8
interleukin 21
chr14_+_70314727 0.25 ENSMUST00000225200.2
early growth response 3
chr17_+_27160356 0.24 ENSMUST00000229490.2
ENSMUST00000201702.5
ENSMUST00000177932.7
ENSMUST00000201349.6
synaptic Ras GTPase activating protein 1 homolog (rat)
chr6_-_58884038 0.24 ENSMUST00000059539.5
nucleosome assembly protein 1-like 5
chr4_+_58285957 0.23 ENSMUST00000081919.12
ENSMUST00000177951.8
ENSMUST00000098059.10
ENSMUST00000179951.2
ENSMUST00000102893.10
ENSMUST00000084578.12
ENSMUST00000098057.10
muscle, skeletal, receptor tyrosine kinase
chr15_+_82230155 0.23 ENSMUST00000023086.15
single-pass membrane protein with aspartate rich tail 1
chr5_-_124492734 0.22 ENSMUST00000031341.11
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr8_-_88686188 0.22 ENSMUST00000109655.9
zinc finger protein 423
chr19_-_41732104 0.22 ENSMUST00000025993.10
slit guidance ligand 1
chr5_+_20112704 0.21 ENSMUST00000115267.7
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr6_-_28126124 0.21 ENSMUST00000115324.9
ENSMUST00000090512.10
glutamate receptor, metabotropic 8
chr10_-_88440996 0.21 ENSMUST00000121629.8
myosin binding protein C, slow-type
chr15_+_98953776 0.20 ENSMUST00000229268.2
peripherin
chr7_+_119289249 0.19 ENSMUST00000047045.10
acyl-CoA synthetase medium-chain family member 4
chr4_+_43669266 0.18 ENSMUST00000107864.8
transmembrane protein 8B
chr11_+_85243970 0.18 ENSMUST00000108056.8
ENSMUST00000108061.8
ENSMUST00000108062.8
ENSMUST00000138423.8
ENSMUST00000092821.10
ENSMUST00000074875.11
breast carcinoma amplified sequence 3
chr3_-_88669551 0.18 ENSMUST00000183267.2
synaptotagmin XI
chr8_+_108669276 0.17 ENSMUST00000220518.2
zinc finger homeobox 3
chr4_+_109092829 0.16 ENSMUST00000030285.8
calreticulin 4
chr9_-_107960528 0.16 ENSMUST00000159372.3
ENSMUST00000160249.8
ring finger protein 123
chr8_-_118400418 0.13 ENSMUST00000173522.8
ENSMUST00000174450.2
short chain dehydrogenase/reductase family 42E, member 1
chr19_-_5553804 0.12 ENSMUST00000189704.2
NSE3 homolog, SMC5-SMC6 complex component like
chr11_-_102187445 0.12 ENSMUST00000107132.3
ENSMUST00000073234.9
ataxin 7-like 3
chr15_+_38740784 0.12 ENSMUST00000226440.3
ENSMUST00000239553.1
brain and acute leukemia, cytoplasmic
chr17_+_87224776 0.12 ENSMUST00000042172.7
transmembrane protein 247
chr12_+_38830081 0.12 ENSMUST00000095767.11
ets variant 1
chr10_-_12745109 0.11 ENSMUST00000218635.2
utrophin
chr9_+_114917902 0.11 ENSMUST00000182363.8
oxysterol binding protein-like 10
chr14_+_50656083 0.11 ENSMUST00000216949.2
olfactory receptor 739
chr17_-_23939700 0.10 ENSMUST00000201734.4
RIKEN cDNA 1520401A03 gene
chr4_+_109092610 0.10 ENSMUST00000106628.8
calreticulin 4
chr1_-_135934080 0.09 ENSMUST00000166193.9
immunoglobulin-like and fibronectin type III domain containing 1
chr1_+_178626003 0.09 ENSMUST00000160789.2
kinesin family member 26B
chr2_+_156317416 0.08 ENSMUST00000029155.16
erythrocyte membrane protein band 4.1 like 1
chr2_-_90900525 0.06 ENSMUST00000153367.2
ENSMUST00000079976.10
solute carrier family 39 (metal ion transporter), member 13
chr3_-_7678785 0.05 ENSMUST00000194279.6
interleukin 7
chr10_+_81464536 0.05 ENSMUST00000129622.2
ankyrin repeat domain 24
chr2_-_90900628 0.04 ENSMUST00000111436.3
ENSMUST00000073575.12
solute carrier family 39 (metal ion transporter), member 13
chr3_-_7678796 0.03 ENSMUST00000192202.6
interleukin 7
chr19_-_47452557 0.02 ENSMUST00000111800.4
SH3 and PX domains 2A
chrX_+_165127688 0.02 ENSMUST00000112223.8
ENSMUST00000112224.8
ENSMUST00000112229.9
ENSMUST00000112228.8
ENSMUST00000112227.9
ENSMUST00000112226.3
glycoprotein m6b
chr5_-_138270995 0.00 ENSMUST00000161665.2
ENSMUST00000100530.8
ENSMUST00000161279.8
ENSMUST00000161647.8
galactose-3-O-sulfotransferase 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 1.2 GO:0060082 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.2 1.4 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.7 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 5.8 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 1.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0060197 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) cloacal septation(GO:0060197)
0.1 0.5 GO:0042414 epinephrine metabolic process(GO:0042414)
0.1 0.6 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 1.2 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.4 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.1 0.6 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.3 GO:0036343 psychomotor behavior(GO:0036343) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.9 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.3 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.3 GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.5 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.6 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.4 GO:1900121 negative regulation of axon regeneration(GO:0048681) negative regulation of receptor binding(GO:1900121)
0.0 0.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0007527 adult somatic muscle development(GO:0007527)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.9 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 1.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0044299 C-fiber(GO:0044299)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.3 4.5 GO:0015250 water channel activity(GO:0015250)
0.2 1.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.6 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 3.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)