Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Hoxb2_Dlx2

Z-value: 1.24

Motif logo

Transcription factors associated with Hoxb2_Dlx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000075588.7 Hoxb2
ENSMUSG00000023391.9 Dlx2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb2mm39_v1_chr11_+_96242422_96242461-0.626.2e-05Click!
Dlx2mm39_v1_chr2_-_71377088_71377103-0.344.4e-02Click!

Activity profile of Hoxb2_Dlx2 motif

Sorted Z-values of Hoxb2_Dlx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb2_Dlx2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr16_+_22737128 6.24 ENSMUST00000170805.9
fetuin beta
chr16_+_22737227 6.15 ENSMUST00000231880.2
fetuin beta
chr16_+_22737050 5.99 ENSMUST00000231768.2
fetuin beta
chr19_-_7943365 5.96 ENSMUST00000182102.8
ENSMUST00000075619.5
solute carrier family 22, member 27
chr3_+_59989282 4.76 ENSMUST00000029326.6
succinate receptor 1
chrM_+_10167 3.70 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr1_-_140111138 3.03 ENSMUST00000111976.9
ENSMUST00000066859.13
complement component factor h
chrM_+_9870 2.96 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr1_-_140111018 2.89 ENSMUST00000192880.6
ENSMUST00000111977.8
complement component factor h
chr9_-_71070506 2.83 ENSMUST00000074465.9
aquaporin 9
chr5_-_87240405 2.80 ENSMUST00000132667.2
ENSMUST00000145617.8
ENSMUST00000094649.11
UDP glucuronosyltransferase 2 family, polypeptide B36
chr3_+_62327089 2.54 ENSMUST00000161057.2
Rho guanine nucleotide exchange factor (GEF) 26
chr15_+_31224616 2.41 ENSMUST00000186547.7
death-associated protein
chr10_+_127734384 2.31 ENSMUST00000047134.8
4short chain dehydrogenase/reductase family 9C, member 7
chr11_-_99213769 2.20 ENSMUST00000038004.3
keratin 25
chr14_+_51333816 2.15 ENSMUST00000169895.3
ribonuclease, RNase A family 4
chr17_-_35100980 1.94 ENSMUST00000152417.8
ENSMUST00000146299.8
complement component 2 (within H-2S)
predicted gene 20547
chr14_+_33662976 1.92 ENSMUST00000100720.2
growth differentiation factor 2
chr14_+_55797468 1.86 ENSMUST00000147981.2
ENSMUST00000133256.8
DDB1 and CUL4 associated factor 11
chr2_+_67935015 1.83 ENSMUST00000042456.4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr15_-_60793115 1.81 ENSMUST00000096418.5
alpha-1-B glycoprotein
chr5_-_87716882 1.76 ENSMUST00000113314.3
sulfotransferase family 1D, member 1
chr19_+_44980565 1.73 ENSMUST00000179305.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr15_+_31224555 1.70 ENSMUST00000186109.2
death-associated protein
chr13_-_53627110 1.67 ENSMUST00000021922.10
msh homeobox 2
chr1_+_74324089 1.63 ENSMUST00000113805.8
ENSMUST00000027370.13
ENSMUST00000087226.11
paroxysmal nonkinesiogenic dyskinesia
chr1_+_88128323 1.62 ENSMUST00000049289.9
UDP glucuronosyltransferase 1 family, polypeptide A2
chr17_-_35101069 1.61 ENSMUST00000025230.15
complement component 2 (within H-2S)
chr17_-_84154196 1.49 ENSMUST00000234214.2
3-hydroxyanthranilate 3,4-dioxygenase
chr6_+_37847721 1.49 ENSMUST00000031859.14
ENSMUST00000120428.8
tripartite motif-containing 24
chr7_-_48497771 1.37 ENSMUST00000032658.14
cysteine and glycine-rich protein 3
chr3_-_75177378 1.35 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr10_+_53213763 1.34 ENSMUST00000219491.2
ENSMUST00000163319.9
ENSMUST00000220197.2
ENSMUST00000046221.8
ENSMUST00000218468.2
ENSMUST00000219921.2
phospholamban
chr18_-_39000056 1.34 ENSMUST00000236630.2
ENSMUST00000237356.2
fibroblast growth factor 1
chr2_+_22959452 1.32 ENSMUST00000155602.4
acyl-Coenzyme A binding domain containing 5
chr5_+_90708962 1.31 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chrM_+_7006 1.29 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr4_-_104733580 1.28 ENSMUST00000064873.9
ENSMUST00000106808.10
ENSMUST00000048947.15
complement component 8, alpha polypeptide
chr16_+_42727926 1.28 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr17_-_84154173 1.28 ENSMUST00000000687.9
3-hydroxyanthranilate 3,4-dioxygenase
chr7_+_51528788 1.28 ENSMUST00000107591.9
growth arrest specific 2
chr12_+_111780604 1.28 ENSMUST00000021714.9
ENSMUST00000223211.2
ENSMUST00000222843.2
ENSMUST00000221375.2
zinc finger, FYVE domain containing 21
chr10_-_44024843 1.27 ENSMUST00000200401.2
crystallin beta-gamma domain containing 1
chr6_-_138056914 1.27 ENSMUST00000171804.4
solute carrier family 15, member 5
chr2_-_165997551 1.25 ENSMUST00000109249.9
ENSMUST00000146497.9
sulfatase 2
chr3_-_157630690 1.21 ENSMUST00000118539.2
cystathionase (cystathionine gamma-lyase)
chr19_-_42117420 1.20 ENSMUST00000161873.2
ENSMUST00000018965.4
arginine vasopressin-induced 1
chr18_-_38999755 1.19 ENSMUST00000115582.8
ENSMUST00000236060.2
fibroblast growth factor 1
chr1_+_88093726 1.17 ENSMUST00000097659.5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr11_-_43792013 1.16 ENSMUST00000067258.9
ENSMUST00000139906.2
adrenergic receptor, alpha 1b
chrM_+_9459 1.15 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr2_-_165997179 1.14 ENSMUST00000088086.4
sulfatase 2
chr13_+_23991010 1.13 ENSMUST00000006786.11
ENSMUST00000099697.3
solute carrier family 17 (sodium phosphate), member 2
chr16_+_37400590 1.12 ENSMUST00000159787.8
homogentisate 1, 2-dioxygenase
chr3_-_49711765 1.12 ENSMUST00000035931.13
protocadherin 18
chr16_+_37400500 1.09 ENSMUST00000160847.2
homogentisate 1, 2-dioxygenase
chr7_-_100306160 1.06 ENSMUST00000107046.8
ENSMUST00000107045.9
ENSMUST00000139708.9
pleckstrin homology domain containing, family B (evectins) member 1
chr17_+_14087827 1.05 ENSMUST00000239324.2
afadin, adherens junction formation factor
chr2_+_70305267 1.03 ENSMUST00000100043.3
trans-acting transcription factor 5
chr6_-_115569504 1.03 ENSMUST00000112957.2
makorin, ring finger protein 2, opposite strand
chr7_+_126549692 1.02 ENSMUST00000106335.8
ENSMUST00000146017.3
seizure related 6 homolog like 2
chrM_+_11735 1.02 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr14_+_55797443 1.01 ENSMUST00000117236.8
DDB1 and CUL4 associated factor 11
chr5_+_90666791 1.01 ENSMUST00000113179.9
ENSMUST00000128740.2
afamin
chr7_+_51530060 1.00 ENSMUST00000145049.2
growth arrest specific 2
chr3_-_49711706 0.99 ENSMUST00000191794.2
protocadherin 18
chr15_+_31224460 0.99 ENSMUST00000044524.16
death-associated protein
chr2_+_83554770 0.98 ENSMUST00000141725.3
integrin alpha V
chr18_+_36414122 0.97 ENSMUST00000051301.6
purine rich element binding protein A
chr16_-_45544960 0.96 ENSMUST00000096057.5
transgelin 3
chr15_+_31225302 0.96 ENSMUST00000186425.7
death-associated protein
chr3_-_54962899 0.95 ENSMUST00000199144.5
cyclin A1
chr10_-_107321938 0.94 ENSMUST00000000445.2
myogenic factor 5
chr5_-_134776101 0.92 ENSMUST00000015138.13
elastin
chr11_-_99412084 0.91 ENSMUST00000076948.2
keratin 39
chr5_+_108842294 0.89 ENSMUST00000013633.12
fibroblast growth factor receptor-like 1
chr19_-_39637489 0.87 ENSMUST00000067328.7
cytochrome P450, family 2, subfamily c, polypeptide 67
chrM_+_8603 0.86 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr3_-_19319123 0.85 ENSMUST00000121951.2
phosphodiesterase 7A
chr7_+_126550009 0.85 ENSMUST00000106332.3
seizure related 6 homolog like 2
chr14_-_118289557 0.84 ENSMUST00000022725.4
dopachrome tautomerase
chr14_-_64654397 0.84 ENSMUST00000210428.2
methionine sulfoxide reductase A
chr9_+_55448432 0.84 ENSMUST00000034869.11
insulin related protein 2 (islet 2)
chr11_-_95966407 0.83 ENSMUST00000107686.8
ENSMUST00000107684.2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
chr14_-_68771138 0.83 ENSMUST00000022640.8
a disintegrin and metallopeptidase domain 7
chr16_-_48592319 0.83 ENSMUST00000239408.2
T cell receptor associated transmembrane adaptor 1
chr15_+_39522905 0.82 ENSMUST00000226410.2
regulating synaptic membrane exocytosis 2
chr8_-_85573489 0.82 ENSMUST00000003912.7
calreticulin
chr15_-_13173736 0.82 ENSMUST00000036439.6
cadherin 6
chr7_+_143792455 0.81 ENSMUST00000239495.2
SH3 and multiple ankyrin repeat domains 2
chr8_+_46111703 0.81 ENSMUST00000134675.8
ENSMUST00000139869.8
ENSMUST00000126067.8
sorbin and SH3 domain containing 2
chr15_-_101801351 0.79 ENSMUST00000100179.2
keratin 76
chr6_+_56901007 0.78 ENSMUST00000176838.2
vomeronasal 1 receptor 4
chr18_+_84106796 0.77 ENSMUST00000235383.2
zinc binding alcohol dehydrogenase, domain containing 2
chr9_+_107765320 0.77 ENSMUST00000191906.6
ENSMUST00000035202.4
MON1 homolog A, secretory traffciking associated
chr9_+_32027335 0.77 ENSMUST00000174641.8
Rho GTPase activating protein 32
chr11_-_99412162 0.76 ENSMUST00000107445.8
keratin 39
chr6_-_84565613 0.75 ENSMUST00000204146.3
cytochrome P450, family 26, subfamily b, polypeptide 1
chr14_-_36820304 0.73 ENSMUST00000022337.11
cadherin-related family member 1
chr5_+_42225303 0.72 ENSMUST00000087332.5
predicted gene 16223
chr2_+_83642910 0.72 ENSMUST00000051454.4
family with sequence similarity 171, member B
chr7_+_65343156 0.72 ENSMUST00000032726.14
ENSMUST00000107495.5
ENSMUST00000143508.3
ENSMUST00000129166.3
ENSMUST00000206517.2
ENSMUST00000206837.2
ENSMUST00000206628.2
ENSMUST00000206361.2
TM2 domain containing 3
chr18_+_9707595 0.72 ENSMUST00000234965.2
collectin sub-family member 12
chr2_+_22959223 0.72 ENSMUST00000114523.10
acyl-Coenzyme A binding domain containing 5
chrM_+_7758 0.71 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr10_-_8632519 0.70 ENSMUST00000212869.2
SAM and SH3 domain containing 1
chr16_-_48592372 0.67 ENSMUST00000231701.3
T cell receptor associated transmembrane adaptor 1
chr6_+_30541581 0.67 ENSMUST00000096066.5
carboxypeptidase A2, pancreatic
chr5_-_86521273 0.67 ENSMUST00000031175.12
transmembrane protease, serine 11d
chr2_+_59442378 0.66 ENSMUST00000112568.8
ENSMUST00000037526.11
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr6_-_147165623 0.66 ENSMUST00000052296.9
ENSMUST00000204197.2
parathyroid hormone-like peptide
chr3_-_92031247 0.65 ENSMUST00000070284.4
proline rich 9
chr18_+_56565188 0.65 ENSMUST00000070166.6
GRAM domain containing 3
chr15_+_100768776 0.64 ENSMUST00000108909.9
sodium channel, voltage-gated, type VIII, alpha
chrX_+_113384297 0.63 ENSMUST00000133447.2
kelch-like 4
chr9_-_16289527 0.63 ENSMUST00000082170.6
FAT atypical cadherin 3
chr2_+_83554741 0.62 ENSMUST00000028499.11
integrin alpha V
chr15_-_37458768 0.62 ENSMUST00000116445.9
neurocalcin delta
chr4_+_122730027 0.61 ENSMUST00000030412.11
ENSMUST00000121870.8
ENSMUST00000097902.5
palmitoyl-protein thioesterase 1
chr7_-_12829100 0.61 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr6_+_40619913 0.61 ENSMUST00000238599.2
maltase-glucoamylase
chr12_-_83609217 0.61 ENSMUST00000222448.2
zinc finger, FYVE domain containing 1
chr16_-_75563645 0.60 ENSMUST00000114244.2
ENSMUST00000046283.16
heat shock protein 70 family, member 13
chr8_+_84728123 0.60 ENSMUST00000060357.15
ENSMUST00000239176.2
RIKEN cDNA 1700067K01 gene
chr3_+_122213420 0.60 ENSMUST00000029766.9
breast cancer anti-estrogen resistance 3
chr17_-_29226700 0.59 ENSMUST00000233441.2
serine/threonine kinase 38
chr4_-_14621669 0.58 ENSMUST00000143105.2
solute carrier family 26, member 7
chr7_+_63835285 0.58 ENSMUST00000206263.2
ENSMUST00000206107.2
ENSMUST00000205731.2
ENSMUST00000206706.2
ENSMUST00000205690.2
transient receptor potential cation channel, subfamily M, member 1
chr15_-_96929086 0.58 ENSMUST00000230086.2
solute carrier family 38, member 4
chr3_-_88194517 0.57 ENSMUST00000165196.8
predicted gene, 38392
chr9_+_121780054 0.56 ENSMUST00000043011.9
ENSMUST00000214536.3
ENSMUST00000215990.3
golgi associated kinase 1A
chr12_-_56660054 0.56 ENSMUST00000072631.6
NK2 homeobox 9
chr10_-_12689345 0.55 ENSMUST00000217899.2
utrophin
chrM_+_7779 0.55 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr5_+_14075281 0.55 ENSMUST00000073957.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_-_14374794 0.54 ENSMUST00000190337.7
EYA transcriptional coactivator and phosphatase 1
chr6_-_83654789 0.54 ENSMUST00000037882.8
CD207 antigen
chr2_+_27055245 0.53 ENSMUST00000000910.7
dopamine beta hydroxylase
chrX_-_99638466 0.53 ENSMUST00000053373.2
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr4_-_14621497 0.53 ENSMUST00000149633.2
solute carrier family 26, member 7
chr7_-_126183716 0.53 ENSMUST00000150311.8
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr4_+_109835224 0.52 ENSMUST00000061187.4
doublesex and mab-3 related transcription factor like family A2
chr11_+_99764215 0.52 ENSMUST00000093936.5
keratin associated protein 9-1
chr17_-_29226886 0.52 ENSMUST00000232723.2
serine/threonine kinase 38
chr6_-_116084810 0.52 ENSMUST00000204353.3
transmembrane and coiled coil domains 1
chr3_+_138019040 0.52 ENSMUST00000013455.13
ENSMUST00000106247.2
alcohol dehydrogenase 6A (class V)
chr3_-_154036180 0.52 ENSMUST00000177846.8
LIM homeobox protein 8
chr4_-_14621805 0.52 ENSMUST00000042221.14
solute carrier family 26, member 7
chr12_-_104439589 0.51 ENSMUST00000021513.6
goosecoid homeobox
chr14_-_80008745 0.51 ENSMUST00000039568.11
ENSMUST00000195355.2
protocadherin 8
chr6_-_125357756 0.50 ENSMUST00000042647.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr2_-_45000250 0.50 ENSMUST00000201211.4
ENSMUST00000177302.8
zinc finger E-box binding homeobox 2
chr2_+_69727563 0.49 ENSMUST00000055758.16
ENSMUST00000112251.9
ubiquitin protein ligase E3 component n-recognin 3
chr2_-_5680801 0.49 ENSMUST00000114987.4
calcium/calmodulin-dependent protein kinase ID
chr1_-_14374842 0.49 ENSMUST00000188857.7
ENSMUST00000185453.7
EYA transcriptional coactivator and phosphatase 1
chr7_-_126183392 0.49 ENSMUST00000128970.8
ENSMUST00000116269.9
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr18_-_81029986 0.49 ENSMUST00000057950.9
spalt like transcription factor 3
chr2_-_77533596 0.49 ENSMUST00000171063.8
zinc finger protein 385B
chr2_+_69727599 0.49 ENSMUST00000131553.2
ubiquitin protein ligase E3 component n-recognin 3
chr5_-_23881353 0.48 ENSMUST00000198661.5
serine/arginine-rich protein specific kinase 2
chr16_+_44914397 0.48 ENSMUST00000061050.6
coiled-coil domain containing 80
chr4_+_108576846 0.48 ENSMUST00000178992.2
RIKEN cDNA 3110021N24 gene
chrX_+_138464065 0.48 ENSMUST00000113027.8
ring finger protein 128
chr7_+_63835154 0.48 ENSMUST00000177102.8
transient receptor potential cation channel, subfamily M, member 1
chr14_+_79086492 0.48 ENSMUST00000040990.7
von Willebrand factor A domain containing 8
chr3_-_54962922 0.48 ENSMUST00000197238.5
cyclin A1
chr18_-_81029751 0.47 ENSMUST00000238808.2
spalt like transcription factor 3
chr8_+_24159669 0.47 ENSMUST00000042352.11
ENSMUST00000207301.2
zinc finger, matrin type 4
chr6_+_114435480 0.47 ENSMUST00000160780.2
histamine receptor H1
chrX_-_142716085 0.47 ENSMUST00000087313.10
doublecortin
chr12_-_57592907 0.46 ENSMUST00000044380.8
forkhead box A1
chr16_-_93726399 0.46 ENSMUST00000177648.8
ENSMUST00000142083.2
claudin 14
chr9_-_96513529 0.46 ENSMUST00000034984.8
RAS p21 protein activator 2
chr2_+_127696548 0.46 ENSMUST00000028859.8
acyl-Coenzyme A oxidase-like
chr11_-_99979052 0.46 ENSMUST00000107419.2
keratin 32
chr14_+_54183465 0.45 ENSMUST00000197130.5
ENSMUST00000103677.3
T cell receptor delta variable 2-1
chr15_+_92495007 0.44 ENSMUST00000035399.10
PDZ domain containing RING finger 4
chr10_+_68987257 0.44 ENSMUST00000167286.8
Rho-related BTB domain containing 1
chr10_-_43934774 0.43 ENSMUST00000239010.2
crystallin beta-gamma domain containing 1
chr6_-_93769426 0.42 ENSMUST00000204788.2
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr9_+_123195986 0.42 ENSMUST00000038863.9
ENSMUST00000216843.2
leucyl-tRNA synthetase, mitochondrial
chr18_-_38336893 0.42 ENSMUST00000194312.2
protocadherin 1
chr14_-_109151590 0.42 ENSMUST00000100322.4
SLIT and NTRK-like family, member 1
chr6_-_41752111 0.42 ENSMUST00000214976.3
olfactory receptor 459
chr1_+_104696235 0.42 ENSMUST00000062528.9
cadherin 20
chr12_+_76580386 0.42 ENSMUST00000219063.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr15_-_8739893 0.41 ENSMUST00000157065.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr13_-_103042294 0.41 ENSMUST00000167462.8
microtubule associated serine/threonine kinase family member 4
chr8_-_62355690 0.41 ENSMUST00000121785.9
ENSMUST00000034057.14
palladin, cytoskeletal associated protein
chr3_-_88368489 0.41 ENSMUST00000166237.8
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr11_+_67689094 0.41 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chr8_+_4288815 0.40 ENSMUST00000003027.14
ENSMUST00000110999.8
mitogen-activated protein kinase kinase 7
chr7_-_90125178 0.40 ENSMUST00000032843.9
transmembrane protein 126B
chr15_+_21111428 0.40 ENSMUST00000075132.8
cadherin 12
chr14_-_63221950 0.39 ENSMUST00000100493.3
defensin beta 48
chrX_+_8233217 0.39 ENSMUST00000115584.2
synovial sarcoma, X member B9
chr11_+_67090878 0.39 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr1_+_88234454 0.39 ENSMUST00000040210.14
transient receptor potential cation channel, subfamily M, member 8
chr3_+_93301003 0.39 ENSMUST00000045912.3
repetin
chr1_-_14380418 0.39 ENSMUST00000027066.13
ENSMUST00000168081.9
EYA transcriptional coactivator and phosphatase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.7 2.0 GO:2000536 negative regulation of entry of bacterium into host cell(GO:2000536)
0.7 5.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.6 1.7 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.5 1.4 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.4 6.0 GO:0015747 urate transport(GO:0015747)
0.4 3.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.4 1.2 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.4 2.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.3 18.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.3 2.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 2.8 GO:0046874 quinolinate metabolic process(GO:0046874)
0.3 1.2 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.3 0.8 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.3 0.8 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.3 1.8 GO:0000103 sulfate assimilation(GO:0000103)
0.2 1.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 2.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 1.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 2.8 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.7 GO:0060618 nipple development(GO:0060618)
0.2 0.6 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 1.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 1.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.6 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.2 0.8 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 1.5 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 2.0 GO:0030242 pexophagy(GO:0030242)
0.2 1.6 GO:0019532 oxalate transport(GO:0019532)
0.2 0.5 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.2 1.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 3.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 1.6 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.5 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.4 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.1 0.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 1.3 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.9 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 1.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.3 GO:0035934 corticosterone secretion(GO:0035934)
0.1 0.6 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.5 GO:0035063 nuclear speck organization(GO:0035063)
0.1 5.6 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 2.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 4.4 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 0.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.5 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.4 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.1 0.8 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.1 0.2 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 2.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.2 GO:2000292 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.1 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 2.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.3 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889)
0.1 0.2 GO:0043133 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of hindgut contraction(GO:0060450)
0.1 0.7 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 2.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.2 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.1 0.3 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.1 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.2 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 1.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 2.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.0 0.9 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.8 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.2 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 1.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.1 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.2 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 3.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.5 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.8 GO:0071625 positive regulation of synaptic transmission, glutamatergic(GO:0051968) vocalization behavior(GO:0071625)
0.0 1.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 0.6 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.7 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 1.0 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.5 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.0 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.3 GO:0051645 Golgi localization(GO:0051645)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.9 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0009216 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) dGDP metabolic process(GO:0046066)
0.0 1.8 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.2 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.4 GO:0019236 response to pheromone(GO:0019236)
0.0 0.5 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.1 GO:0010793 regulation of histone H3-K36 methylation(GO:0000414) regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.4 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.6 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.2 GO:0097186 amelogenesis(GO:0097186)
0.0 0.2 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0034686 integrin alphav-beta3 complex(GO:0034683) integrin alphav-beta8 complex(GO:0034686)
0.4 1.6 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.3 0.9 GO:0016014 dystrobrevin complex(GO:0016014)
0.2 1.1 GO:0035841 new growing cell tip(GO:0035841)
0.2 1.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 0.5 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.1 1.3 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.1 2.1 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.1 0.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 9.6 GO:0070469 respiratory chain(GO:0070469)
0.1 0.8 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.1 2.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.8 GO:0005883 neurofilament(GO:0005883)
0.0 5.5 GO:0005882 intermediate filament(GO:0005882)
0.0 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 1.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 7.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 30.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.7 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 3.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0002102 podosome(GO:0002102)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.9 GO:0001851 complement component C3b binding(GO:0001851)
0.8 18.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 2.8 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.5 1.8 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 1.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.4 6.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 1.0 GO:0008431 vitamin E binding(GO:0008431)
0.3 0.9 GO:0001571 non-tyrosine kinase fibroblast growth factor receptor activity(GO:0001571)
0.3 9.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 1.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 6.1 GO:0070513 death domain binding(GO:0070513)
0.3 2.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 2.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.5 GO:0034056 estrogen response element binding(GO:0034056)
0.2 0.8 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.2 1.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 1.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.8 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2 1.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.5 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.2 0.5 GO:0045030 UTP-activated nucleotide receptor activity(GO:0045030)
0.1 5.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.4 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.1 5.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.5 GO:0051381 histamine binding(GO:0051381)
0.1 2.5 GO:0044548 S100 protein binding(GO:0044548)
0.1 2.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.6 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.3 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.5 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 1.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.3 GO:0001848 complement binding(GO:0001848)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 2.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 2.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 1.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 2.3 GO:0004540 ribonuclease activity(GO:0004540)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.2 GO:0005550 pheromone binding(GO:0005550)
0.0 0.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.3 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 2.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 2.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 1.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein