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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hoxb5

Z-value: 1.53

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Transcription factors associated with Hoxb5

Gene Symbol Gene ID Gene Info
Hoxb5
ENSMUSG00000038700.5 Hoxb5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb5mm39_v1_chr11_+_96194333_961943780.372.7e-02Click!

Activity profile of Hoxb5 motif

Sorted Z-values of Hoxb5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_121613177 16.26 ENSMUST00000032203.9
A2m
alpha-2-macroglobulin
chr7_+_142558837 8.33 ENSMUST00000207211.2
Tspan32
tetraspanin 32
chr7_+_142559414 6.08 ENSMUST00000082008.12
ENSMUST00000105925.8
ENSMUST00000105924.8
Tspan32
tetraspanin 32
chr17_+_47904355 5.80 ENSMUST00000182209.8
Ccnd3
cyclin D3
chr17_+_47904441 5.70 ENSMUST00000182874.3
Ccnd3
cyclin D3
chr2_+_125089110 5.48 ENSMUST00000082122.14
Dut
deoxyuridine triphosphatase
chr7_+_142559375 5.43 ENSMUST00000075172.12
ENSMUST00000105923.8
Tspan32
tetraspanin 32
chr6_+_145067457 5.27 ENSMUST00000032396.13
Lrmp
lymphoid-restricted membrane protein
chr7_+_142558783 5.03 ENSMUST00000009396.13
Tspan32
tetraspanin 32
chr12_-_36092475 4.84 ENSMUST00000020896.17
Tspan13
tetraspanin 13
chr6_+_72526236 3.95 ENSMUST00000114071.8
Capg
capping protein (actin filament), gelsolin-like
chr7_+_126808016 3.72 ENSMUST00000206204.2
ENSMUST00000206772.2
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr7_+_142559475 3.52 ENSMUST00000143512.3
Tspan32
tetraspanin 32
chr10_+_128745214 3.13 ENSMUST00000220308.2
Cd63
CD63 antigen
chr10_-_88518878 2.93 ENSMUST00000004473.15
Spic
Spi-C transcription factor (Spi-1/PU.1 related)
chr14_+_31881822 2.92 ENSMUST00000163336.8
ENSMUST00000169722.8
ENSMUST00000168385.8
Ncoa4
nuclear receptor coactivator 4
chr7_-_44181477 2.82 ENSMUST00000098483.9
ENSMUST00000035323.6
Spib
Spi-B transcription factor (Spi-1/PU.1 related)
chr4_-_149221998 2.81 ENSMUST00000176124.8
ENSMUST00000177408.2
ENSMUST00000105695.2
Cenps
centromere protein S
chr7_+_25327028 2.73 ENSMUST00000076034.8
B3gnt8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr12_-_113542610 2.68 ENSMUST00000195468.6
ENSMUST00000103442.3
Ighv5-2
immunoglobulin heavy variable 5-2
chr7_-_133310779 2.68 ENSMUST00000124759.2
ENSMUST00000106144.8
ENSMUST00000106145.10
Uros
uroporphyrinogen III synthase
chr17_+_84013575 2.56 ENSMUST00000112350.8
ENSMUST00000112349.9
ENSMUST00000112352.10
ENSMUST00000067826.15
Mta3
metastasis associated 3
chr8_+_13389656 2.55 ENSMUST00000210165.2
ENSMUST00000170909.2
Tfdp1
transcription factor Dp 1
chr7_-_133310687 2.53 ENSMUST00000106146.8
Uros
uroporphyrinogen III synthase
chr8_+_95807814 2.48 ENSMUST00000034239.9
Katnb1
katanin p80 (WD40-containing) subunit B 1
chr6_+_72526414 2.45 ENSMUST00000155705.8
Capg
capping protein (actin filament), gelsolin-like
chr6_-_128339775 2.41 ENSMUST00000112152.8
ENSMUST00000057421.15
ENSMUST00000112151.2
Rhno1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr4_-_149222057 2.39 ENSMUST00000030813.10
Cenps
centromere protein S
chr10_-_127047396 2.34 ENSMUST00000013970.9
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr7_-_126807581 2.32 ENSMUST00000120705.3
Tbc1d10b
TBC1 domain family, member 10b
chrX_+_20554193 2.13 ENSMUST00000115364.8
Cdk16
cyclin-dependent kinase 16
chr19_-_45804446 2.10 ENSMUST00000079431.10
ENSMUST00000026247.13
ENSMUST00000162528.9
Kcnip2
Kv channel-interacting protein 2
chr7_-_30850429 2.06 ENSMUST00000085636.13
ENSMUST00000001280.14
Gramd1a
GRAM domain containing 1A
chr12_-_79030250 2.02 ENSMUST00000070174.14
Tmem229b
transmembrane protein 229B
chr4_-_141602190 2.01 ENSMUST00000036854.4
Efhd2
EF hand domain containing 2
chr2_-_164585102 1.91 ENSMUST00000103096.10
Wfdc3
WAP four-disulfide core domain 3
chrX_+_149829131 1.89 ENSMUST00000112685.8
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr8_+_124059414 1.88 ENSMUST00000010298.7
Spire2
spire type actin nucleation factor 2
chr7_-_45116316 1.87 ENSMUST00000033093.10
Bax
BCL2-associated X protein
chr19_-_7218363 1.74 ENSMUST00000236769.2
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr7_-_45116216 1.72 ENSMUST00000210392.2
ENSMUST00000211365.2
Bax
BCL2-associated X protein
chr7_-_44861235 1.70 ENSMUST00000210741.2
ENSMUST00000209466.2
Dkkl1
dickkopf-like 1
chr12_-_79027531 1.65 ENSMUST00000174072.8
Tmem229b
transmembrane protein 229B
chr7_-_44180700 1.50 ENSMUST00000205506.2
Spib
Spi-B transcription factor (Spi-1/PU.1 related)
chr2_-_153067297 1.46 ENSMUST00000099194.4
Tspyl3
TSPY-like 3
chr7_-_45116197 1.44 ENSMUST00000211195.2
ENSMUST00000210019.2
Bax
BCL2-associated X protein
chr4_+_109272828 1.43 ENSMUST00000106618.8
Ttc39a
tetratricopeptide repeat domain 39A
chr2_+_84966569 1.39 ENSMUST00000057019.9
Aplnr
apelin receptor
chr19_-_7218512 1.38 ENSMUST00000025675.11
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr7_-_100613579 1.27 ENSMUST00000060174.6
P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr7_+_44667377 1.20 ENSMUST00000044111.10
Rras
related RAS viral (r-ras) oncogene
chr5_-_137784912 1.13 ENSMUST00000031740.16
Mepce
methylphosphate capping enzyme
chr11_+_101137786 1.05 ENSMUST00000107282.4
Ramp2
receptor (calcitonin) activity modifying protein 2
chr3_+_67281449 1.04 ENSMUST00000061322.10
Mlf1
myeloid leukemia factor 1
chr5_-_137784943 1.02 ENSMUST00000132726.2
Mepce
methylphosphate capping enzyme
chr8_+_105067159 0.96 ENSMUST00000212948.2
ENSMUST00000034343.5
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr1_+_92878566 0.95 ENSMUST00000185421.2
Gpr35
G protein-coupled receptor 35
chr17_+_28911529 0.83 ENSMUST00000114752.3
Mapk14
mitogen-activated protein kinase 14
chrX_-_56438380 0.80 ENSMUST00000143310.2
ENSMUST00000098470.9
ENSMUST00000114726.8
Rbmx
RNA binding motif protein, X chromosome
chr13_-_31158031 0.80 ENSMUST00000021785.8
Exoc2
exocyst complex component 2
chr8_-_26087475 0.79 ENSMUST00000210810.2
ENSMUST00000210616.2
ENSMUST00000079160.8
Letm2
leucine zipper-EF-hand containing transmembrane protein 2
chr2_+_26863428 0.70 ENSMUST00000014996.14
Adamts13
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
chr9_+_77959206 0.67 ENSMUST00000024104.9
Gcm1
glial cells missing homolog 1
chr18_-_61840654 0.64 ENSMUST00000025472.7
Pcyox1l
prenylcysteine oxidase 1 like
chr4_+_14864076 0.63 ENSMUST00000029875.4
Pip4p2
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
chr18_+_74401322 0.58 ENSMUST00000224047.2
Mbd1
methyl-CpG binding domain protein 1
chr3_+_67281424 0.55 ENSMUST00000077916.12
Mlf1
myeloid leukemia factor 1
chr16_-_64422716 0.55 ENSMUST00000209382.3
Csnka2ip
casein kinase 2, alpha prime interacting protein
chr18_-_38131766 0.51 ENSMUST00000236588.2
ENSMUST00000237272.2
ENSMUST00000236134.2
Arap3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chrX_-_56438322 0.48 ENSMUST00000114730.8
Rbmx
RNA binding motif protein, X chromosome
chr5_-_103359117 0.47 ENSMUST00000112846.8
ENSMUST00000170792.9
ENSMUST00000112847.9
ENSMUST00000238446.3
ENSMUST00000133069.8
Mapk10
mitogen-activated protein kinase 10
chr3_-_103645311 0.44 ENSMUST00000029440.10
Olfml3
olfactomedin-like 3
chr3_+_89122477 0.43 ENSMUST00000029682.11
Thbs3
thrombospondin 3
chr8_+_105066924 0.41 ENSMUST00000212081.2
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr7_+_126895423 0.39 ENSMUST00000117762.8
Itgal
integrin alpha L
chr7_+_126895463 0.35 ENSMUST00000106306.9
ENSMUST00000120857.8
Itgal
integrin alpha L
chr1_-_74583434 0.34 ENSMUST00000189257.7
Usp37
ubiquitin specific peptidase 37
chr19_-_11601007 0.31 ENSMUST00000164792.8
ENSMUST00000189641.2
ENSMUST00000186978.7
ENSMUST00000025583.12
Ms4a2
membrane-spanning 4-domains, subfamily A, member 2
chr11_+_101137231 0.30 ENSMUST00000122006.8
ENSMUST00000151830.2
Ramp2
receptor (calcitonin) activity modifying protein 2
chr7_+_126895531 0.24 ENSMUST00000170971.8
Itgal
integrin alpha L
chr1_-_193052568 0.23 ENSMUST00000016323.11
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr14_-_40726472 0.23 ENSMUST00000153830.8
Prxl2a
peroxiredoxin like 2A
chr3_-_89067462 0.22 ENSMUST00000029686.4
Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chrX_-_9983836 0.21 ENSMUST00000115543.3
ENSMUST00000044789.10
ENSMUST00000115544.9
Srpx
sushi-repeat-containing protein
chr2_-_130471891 0.20 ENSMUST00000110262.3
ENSMUST00000028761.5
Fastkd5
Ubox5
FAST kinase domains 5
U box domain containing 5
chr7_-_140480314 0.17 ENSMUST00000026561.10
Cox8b
cytochrome c oxidase subunit 8B
chrX_-_103244703 0.17 ENSMUST00000087879.11
Nexmif
neurite extension and migration factor
chr2_-_5867734 0.15 ENSMUST00000071016.3
Gm13199
predicted gene 13199
chrX_-_133012457 0.14 ENSMUST00000159259.3
ENSMUST00000113275.10
Nox1
NADPH oxidase 1
chr5_-_24732200 0.13 ENSMUST00000088311.6
Gbx1
gastrulation brain homeobox 1
chrX_-_133012600 0.13 ENSMUST00000033610.13
Nox1
NADPH oxidase 1
chr17_-_80885197 0.12 ENSMUST00000234602.2
Cdkl4
cyclin-dependent kinase-like 4
chr8_-_25086976 0.09 ENSMUST00000033956.7
Ido1
indoleamine 2,3-dioxygenase 1
chr8_-_123768984 0.08 ENSMUST00000212937.2
Ankrd11
ankyrin repeat domain 11
chrX_-_103244784 0.08 ENSMUST00000118314.8
Nexmif
neurite extension and migration factor
chr8_-_26087552 0.07 ENSMUST00000210234.2
ENSMUST00000211422.2
Letm2
leucine zipper-EF-hand containing transmembrane protein 2
chr9_+_107277058 0.07 ENSMUST00000085092.12
ENSMUST00000164988.9
Cacna2d2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr9_+_107277242 0.07 ENSMUST00000166799.8
ENSMUST00000170737.3
Cacna2d2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr1_-_166237341 0.05 ENSMUST00000135673.8
ENSMUST00000169324.8
ENSMUST00000128861.3
Pogk
pogo transposable element with KRAB domain
chr13_-_3995349 0.05 ENSMUST00000058610.8
Ucn3
urocortin 3
chr15_-_34358018 0.05 ENSMUST00000227772.2
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chr1_-_193052533 0.05 ENSMUST00000169907.8
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr10_-_80850712 0.03 ENSMUST00000126317.2
ENSMUST00000092285.10
ENSMUST00000117805.8
Gng7
guanine nucleotide binding protein (G protein), gamma 7
chr7_-_103674780 0.03 ENSMUST00000218535.2
Olfr640
olfactory receptor 640
chr11_-_99045894 0.02 ENSMUST00000103134.4
Ccr7
chemokine (C-C motif) receptor 7
chr5_+_143869875 0.02 ENSMUST00000166847.8
Rsph10b
radial spoke head 10 homolog B (Chlamydomonas)
chr8_+_105066980 0.02 ENSMUST00000211885.2
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr9_+_8900460 0.02 ENSMUST00000070463.10
ENSMUST00000098986.4
Pgr
progesterone receptor
chr5_-_109000467 0.01 ENSMUST00000170419.3
ENSMUST00000233835.2
Vmn2r9
vomeronasal 2, receptor 9
chrX_-_164110372 0.00 ENSMUST00000058787.9
Glra2
glycine receptor, alpha 2 subunit
chr2_-_151474391 0.00 ENSMUST00000137936.2
ENSMUST00000146172.8
ENSMUST00000094456.10
ENSMUST00000148755.8
ENSMUST00000109875.8
ENSMUST00000028951.14
ENSMUST00000109877.10
Snph
syntaphilin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.3 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.6 28.4 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
1.7 5.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
1.7 5.0 GO:1990117 release of matrix enzymes from mitochondria(GO:0032976) B cell receptor apoptotic signaling pathway(GO:1990117)
1.4 5.5 GO:0009223 dUMP biosynthetic process(GO:0006226) pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.7 2.7 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.6 2.5 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.5 3.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.5 1.9 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.4 11.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.3 2.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.3 1.4 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.3 1.0 GO:1904456 negative regulation of neuronal action potential(GO:1904456)
0.3 5.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 2.1 GO:0040031 snRNA modification(GO:0040031)
0.2 2.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 0.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 2.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 1.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 6.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.0 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 2.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.8 GO:0001927 exocyst assembly(GO:0001927)
0.1 1.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.8 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 3.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474) histone H2A acetylation(GO:0043968)
0.1 1.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 4.3 GO:0030225 macrophage differentiation(GO:0030225)
0.1 2.6 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 2.1 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.3 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 0.1 GO:0097374 proprioception(GO:0019230) sensory neuron axon guidance(GO:0097374)
0.0 0.4 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 5.3 GO:0007338 single fertilization(GO:0007338)
0.0 0.6 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 1.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 2.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 2.4 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 1.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 2.9 GO:0001824 blastocyst development(GO:0001824)
0.0 2.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 3.8 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 1.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 28.4 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
1.7 5.0 GO:0097144 BAX complex(GO:0097144)
1.3 5.2 GO:0071821 FANCM-MHF complex(GO:0071821)
1.0 3.1 GO:0031904 endosome lumen(GO:0031904)
0.4 6.4 GO:0090543 Flemming body(GO:0090543)
0.2 1.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 1.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 1.0 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.2 2.9 GO:0044754 autolysosome(GO:0044754)
0.1 10.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.3 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.0 14.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 1.6 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 1.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.7 GO:0016459 myosin complex(GO:0016459)
0.0 2.6 GO:0005776 autophagosome(GO:0005776)
0.0 3.3 GO:0000922 spindle pole(GO:0000922)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 2.4 GO:0001726 ruffle(GO:0001726)
0.0 2.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.3 GO:0019959 interleukin-8 binding(GO:0019959)
0.9 2.7 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.9 5.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.8 2.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5 5.0 GO:0051434 BH3 domain binding(GO:0051434)
0.5 5.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.4 2.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 2.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 3.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.3 1.3 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.2 13.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 1.4 GO:0097643 amylin receptor activity(GO:0097643)
0.2 1.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 1.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.6 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 4.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.6 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.8 GO:0051525 mitogen-activated protein kinase p38 binding(GO:0048273) NFAT protein binding(GO:0051525)
0.1 0.3 GO:0019767 IgE receptor activity(GO:0019767)
0.1 4.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 3.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 2.1 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 2.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 4.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 1.3 GO:0003727 single-stranded RNA binding(GO:0003727)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 5.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 17.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.5 PID E2F PATHWAY E2F transcription factor network
0.0 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 3.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 16.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 14.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 5.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 5.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 5.0 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 2.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 3.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK