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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hoxc10

Z-value: 0.77

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Transcription factors associated with Hoxc10

Gene Symbol Gene ID Gene Info
Hoxc10
ENSMUSG00000022484.8 Hoxc10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxc10mm39_v1_chr15_+_102875229_1028752480.057.5e-01Click!

Activity profile of Hoxc10 motif

Sorted Z-values of Hoxc10 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxc10

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_30623592 2.16 ENSMUST00000217812.2
ENSMUST00000074671.9
Hamp2
hepcidin antimicrobial peptide 2
chr1_-_45542442 1.91 ENSMUST00000086430.5
Col5a2
collagen, type V, alpha 2
chr5_+_90708962 1.71 ENSMUST00000094615.8
ENSMUST00000200765.2
Albfm1
albumin superfamily member 1
chr14_-_47426863 1.49 ENSMUST00000089959.7
Gch1
GTP cyclohydrolase 1
chr2_-_32341408 1.47 ENSMUST00000028160.15
ENSMUST00000113310.9
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr17_-_31363245 1.41 ENSMUST00000024826.8
Tff2
trefoil factor 2 (spasmolytic protein 1)
chr4_+_118217179 1.26 ENSMUST00000006562.6
Hyi
hydroxypyruvate isomerase (putative)
chr6_-_136852792 1.24 ENSMUST00000032342.3
Mgp
matrix Gla protein
chr1_-_71692320 1.01 ENSMUST00000186940.7
ENSMUST00000188894.7
ENSMUST00000188674.7
ENSMUST00000189821.7
ENSMUST00000187938.7
ENSMUST00000190780.7
ENSMUST00000186736.2
ENSMUST00000055226.13
ENSMUST00000186129.7
Fn1
fibronectin 1
chr13_+_25127127 0.97 ENSMUST00000021773.13
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr11_-_120440519 0.87 ENSMUST00000034913.5
Mcrip1
MAPK regulated corepressor interacting protein 1
chr17_+_34043536 0.79 ENSMUST00000048249.8
Ndufa7
NADH:ubiquinone oxidoreductase subunit A7
chrX_-_133442596 0.75 ENSMUST00000054213.5
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr17_+_31652073 0.62 ENSMUST00000237363.2
Pde9a
phosphodiesterase 9A
chr17_+_31652029 0.60 ENSMUST00000136384.9
Pde9a
phosphodiesterase 9A
chr4_-_129472328 0.58 ENSMUST00000052835.9
Fam167b
family with sequence similarity 167, member B
chr11_-_61268879 0.57 ENSMUST00000010267.10
Slc47a1
solute carrier family 47, member 1
chr18_+_20380397 0.53 ENSMUST00000054128.7
Dsg1c
desmoglein 1 gamma
chr9_+_21914083 0.50 ENSMUST00000216344.2
Prkcsh
protein kinase C substrate 80K-H
chr2_-_32277773 0.49 ENSMUST00000050785.14
Lcn2
lipocalin 2
chr7_-_141015240 0.48 ENSMUST00000138865.8
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr11_-_83957889 0.48 ENSMUST00000108101.8
Dusp14
dual specificity phosphatase 14
chr7_-_141014477 0.48 ENSMUST00000106007.10
ENSMUST00000150026.2
ENSMUST00000202840.4
ENSMUST00000133206.9
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr3_+_89173859 0.47 ENSMUST00000040824.2
Dpm3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr2_-_32278245 0.45 ENSMUST00000192241.2
Lcn2
lipocalin 2
chr7_-_139162706 0.40 ENSMUST00000106095.3
Nkx6-2
NK6 homeobox 2
chr11_-_73215442 0.39 ENSMUST00000021119.9
Aspa
aspartoacylase
chrM_+_3906 0.37 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr11_-_100036792 0.36 ENSMUST00000007317.8
Krt19
keratin 19
chrX_+_168468186 0.35 ENSMUST00000112107.8
ENSMUST00000112104.8
Mid1
midline 1
chr2_-_151586063 0.34 ENSMUST00000109869.2
Psmf1
proteasome (prosome, macropain) inhibitor subunit 1
chr16_-_38620688 0.34 ENSMUST00000057767.6
Upk1b
uroplakin 1B
chr6_-_124942457 0.33 ENSMUST00000112439.9
Cops7a
COP9 signalosome subunit 7A
chr6_-_124942366 0.33 ENSMUST00000129446.8
ENSMUST00000032220.15
Cops7a
COP9 signalosome subunit 7A
chr3_-_49711765 0.31 ENSMUST00000035931.13
Pcdh18
protocadherin 18
chr6_-_124942170 0.30 ENSMUST00000148485.2
ENSMUST00000129976.8
Cops7a
COP9 signalosome subunit 7A
chr2_-_35994072 0.27 ENSMUST00000112961.10
ENSMUST00000112966.10
Lhx6
LIM homeobox protein 6
chr3_-_49711706 0.26 ENSMUST00000191794.2
Pcdh18
protocadherin 18
chr17_-_34043320 0.24 ENSMUST00000173879.8
ENSMUST00000166693.3
ENSMUST00000173019.8
Rps28
ribosomal protein S28
chr3_-_88317601 0.24 ENSMUST00000193338.6
ENSMUST00000056370.13
Pmf1
polyamine-modulated factor 1
chr15_+_6451721 0.24 ENSMUST00000163082.2
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr5_+_43672856 0.24 ENSMUST00000076939.10
C1qtnf7
C1q and tumor necrosis factor related protein 7
chr8_+_94537910 0.24 ENSMUST00000138659.9
Gnao1
guanine nucleotide binding protein, alpha O
chr17_-_34043502 0.23 ENSMUST00000087342.13
ENSMUST00000173844.8
Rps28
ribosomal protein S28
chr15_-_101441254 0.23 ENSMUST00000023720.8
Krt84
keratin 84
chr1_+_189460461 0.23 ENSMUST00000097442.9
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr11_-_99134885 0.22 ENSMUST00000103132.10
ENSMUST00000038214.7
Krt222
keratin 222
chr7_-_29605504 0.21 ENSMUST00000053521.15
Zfp27
zinc finger protein 27
chr16_+_29884153 0.20 ENSMUST00000023171.8
Hes1
hes family bHLH transcription factor 1
chr2_-_35994819 0.20 ENSMUST00000148852.4
Lhx6
LIM homeobox protein 6
chr9_-_44473146 0.20 ENSMUST00000215293.2
Cxcr5
chemokine (C-X-C motif) receptor 5
chr19_+_26725589 0.19 ENSMUST00000207812.2
ENSMUST00000175791.9
ENSMUST00000207118.2
ENSMUST00000209085.2
ENSMUST00000112637.10
ENSMUST00000207054.2
ENSMUST00000208589.2
ENSMUST00000176475.9
ENSMUST00000176698.9
ENSMUST00000207832.2
ENSMUST00000177252.9
ENSMUST00000208712.2
ENSMUST00000208186.2
ENSMUST00000208806.2
ENSMUST00000208027.2
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_89821818 0.18 ENSMUST00000216953.3
Olfr1261
olfactory receptor 1261
chr7_-_30428930 0.18 ENSMUST00000207296.2
ENSMUST00000006478.10
Tmem147
transmembrane protein 147
chr6_+_71176811 0.17 ENSMUST00000067492.8
Fabp1
fatty acid binding protein 1, liver
chr14_+_54923655 0.17 ENSMUST00000038539.8
ENSMUST00000228027.2
1700123O20Rik
RIKEN cDNA 1700123O20 gene
chr2_+_83642910 0.17 ENSMUST00000051454.4
Fam171b
family with sequence similarity 171, member B
chrX_+_132809189 0.17 ENSMUST00000113304.2
Srpx2
sushi-repeat-containing protein, X-linked 2
chr11_+_108811168 0.16 ENSMUST00000052915.14
Axin2
axin 2
chr14_+_54454749 0.15 ENSMUST00000103737.3
Traj3
T cell receptor alpha joining 3
chr8_-_25528972 0.15 ENSMUST00000084031.6
Htra4
HtrA serine peptidase 4
chr10_-_38998272 0.15 ENSMUST00000136546.8
Fam229b
family with sequence similarity 229, member B
chr7_-_30428746 0.15 ENSMUST00000209065.2
ENSMUST00000208169.2
Tmem147
transmembrane protein 147
chr10_-_116732813 0.14 ENSMUST00000048229.9
Myrfl
myelin regulatory factor-like
chr2_-_69542805 0.14 ENSMUST00000102706.4
ENSMUST00000073152.13
Fastkd1
FAST kinase domains 1
chr11_+_108811626 0.14 ENSMUST00000140821.2
Axin2
axin 2
chr7_-_30750856 0.13 ENSMUST00000073892.6
Fxyd7
FXYD domain-containing ion transport regulator 7
chr3_-_63758672 0.12 ENSMUST00000162269.9
ENSMUST00000159676.9
ENSMUST00000175947.8
Plch1
phospholipase C, eta 1
chr11_+_96214078 0.12 ENSMUST00000093944.10
Hoxb3
homeobox B3
chr6_-_52203146 0.12 ENSMUST00000114425.3
Hoxa9
homeobox A9
chr2_+_73102269 0.12 ENSMUST00000090813.6
Sp9
trans-acting transcription factor 9
chr19_+_55882942 0.11 ENSMUST00000142291.8
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr2_+_89804937 0.11 ENSMUST00000214630.2
ENSMUST00000111512.10
ENSMUST00000144710.3
ENSMUST00000216678.2
Olfr1260
olfactory receptor 1260
chr2_+_113235475 0.11 ENSMUST00000238883.2
Fmn1
formin 1
chr10_+_41366433 0.10 ENSMUST00000105507.5
Ppil6
peptidylprolyl isomerase (cyclophilin)-like 6
chr2_+_177783713 0.10 ENSMUST00000103066.10
Phactr3
phosphatase and actin regulator 3
chr15_-_101336669 0.10 ENSMUST00000081945.5
Krt87
keratin 87
chr10_+_34265969 0.09 ENSMUST00000105511.2
Col10a1
collagen, type X, alpha 1
chr11_+_96085118 0.09 ENSMUST00000062709.4
Hoxb13
homeobox B13
chr2_+_3115250 0.09 ENSMUST00000072955.12
Fam171a1
family with sequence similarity 171, member A1
chr10_-_33920300 0.09 ENSMUST00000048052.7
Calhm4
calcium homeostasis modulator family member 4
chr8_-_62576140 0.09 ENSMUST00000034052.14
ENSMUST00000034054.9
Anxa10
annexin A10
chr7_-_103320398 0.08 ENSMUST00000062144.4
Olfr624
olfactory receptor 624
chr5_+_149942140 0.08 ENSMUST00000065745.10
ENSMUST00000110496.5
ENSMUST00000201612.2
Rxfp2
relaxin/insulin-like family peptide receptor 2
chr5_+_43673093 0.08 ENSMUST00000144558.3
C1qtnf7
C1q and tumor necrosis factor related protein 7
chr11_+_115824108 0.08 ENSMUST00000140991.2
Sap30bp
SAP30 binding protein
chr11_-_99884818 0.07 ENSMUST00000105049.2
Krtap17-1
keratin associated protein 17-1
chr9_+_37119472 0.07 ENSMUST00000034632.10
Tmem218
transmembrane protein 218
chr8_-_94739469 0.07 ENSMUST00000053766.14
Amfr
autocrine motility factor receptor
chr15_+_21111428 0.07 ENSMUST00000075132.8
Cdh12
cadherin 12
chr15_-_101422054 0.07 ENSMUST00000230067.3
Gm49425
predicted gene, 49425
chr12_-_113912416 0.07 ENSMUST00000103464.3
Ighv4-1
immunoglobulin heavy variable 4-1
chr17_-_35293447 0.07 ENSMUST00000007259.4
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr10_-_28862289 0.07 ENSMUST00000152363.8
ENSMUST00000015663.7
2310057J18Rik
RIKEN cDNA 2310057J18 gene
chr7_-_30750828 0.07 ENSMUST00000206341.2
Fxyd7
FXYD domain-containing ion transport regulator 7
chr10_+_90412827 0.06 ENSMUST00000182550.8
ENSMUST00000099364.12
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_+_106245792 0.06 ENSMUST00000172306.3
Dusp7
dual specificity phosphatase 7
chr2_-_129213050 0.06 ENSMUST00000028881.14
Il1b
interleukin 1 beta
chr14_+_66043281 0.06 ENSMUST00000022612.10
Pbk
PDZ binding kinase
chr16_-_89305201 0.06 ENSMUST00000056118.4
Krtap7-1
keratin associated protein 7-1
chr18_-_43032514 0.06 ENSMUST00000236238.2
Ppp2r2b
protein phosphatase 2, regulatory subunit B, beta
chr2_-_86180622 0.05 ENSMUST00000099894.5
ENSMUST00000213564.3
Olfr1055
olfactory receptor 1055
chr1_-_144124871 0.05 ENSMUST00000189061.7
Rgs1
regulator of G-protein signaling 1
chr1_-_36283326 0.05 ENSMUST00000046875.14
Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr13_-_21765822 0.05 ENSMUST00000206526.3
ENSMUST00000213912.2
Olfr1364
olfactory receptor 1364
chr14_-_50479161 0.05 ENSMUST00000214388.2
Olfr731
olfactory receptor 731
chr5_-_67256578 0.04 ENSMUST00000012664.11
Phox2b
paired-like homeobox 2b
chr1_-_69147185 0.04 ENSMUST00000121473.8
Erbb4
erb-b2 receptor tyrosine kinase 4
chr18_-_43032359 0.04 ENSMUST00000117687.8
Ppp2r2b
protein phosphatase 2, regulatory subunit B, beta
chr1_+_66426127 0.04 ENSMUST00000145419.8
Map2
microtubule-associated protein 2
chr10_-_49659355 0.04 ENSMUST00000105484.10
ENSMUST00000218598.2
ENSMUST00000079751.9
ENSMUST00000218441.2
Grik2
glutamate receptor, ionotropic, kainate 2 (beta 2)
chr4_-_58787716 0.04 ENSMUST00000216719.2
Olfr267
olfactory receptor 267
chr11_-_99920694 0.04 ENSMUST00000073890.4
Krt33b
keratin 33B
chr1_-_144124787 0.03 ENSMUST00000185714.2
Rgs1
regulator of G-protein signaling 1
chr18_+_20443795 0.03 ENSMUST00000077146.4
Dsg1a
desmoglein 1 alpha
chr4_+_102111936 0.03 ENSMUST00000106907.9
Pde4b
phosphodiesterase 4B, cAMP specific
chr2_-_27354006 0.03 ENSMUST00000164296.8
Brd3
bromodomain containing 3
chrX_+_138464065 0.02 ENSMUST00000113027.8
Rnf128
ring finger protein 128
chr3_+_31956814 0.02 ENSMUST00000192429.6
ENSMUST00000191869.6
ENSMUST00000178668.2
ENSMUST00000119970.8
Kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chrX_-_49108236 0.02 ENSMUST00000213556.3
ENSMUST00000213463.2
Olfr1323
olfactory receptor 1323
chr2_+_89821565 0.02 ENSMUST00000111509.3
ENSMUST00000213909.3
Olfr1261
olfactory receptor 1261
chr11_-_115824290 0.01 ENSMUST00000021097.10
Recql5
RecQ protein-like 5
chr3_-_117153802 0.01 ENSMUST00000197743.2
Plppr4
phospholipid phosphatase related 4
chr3_+_63988968 0.01 ENSMUST00000029406.6
Vmn2r1
vomeronasal 2, receptor 1
chr8_-_18791557 0.01 ENSMUST00000033846.7
Angpt2
angiopoietin 2
chr1_+_17672117 0.01 ENSMUST00000088476.4
Pi15
peptidase inhibitor 15
chr12_-_69838004 0.01 ENSMUST00000221646.2
Cdkl1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr12_+_117621644 0.01 ENSMUST00000222105.2
Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr9_-_21199232 0.01 ENSMUST00000184326.8
ENSMUST00000038671.10
Kri1
KRI1 homolog
chr6_-_23655130 0.01 ENSMUST00000104979.2
Rnf148
ring finger protein 148
chr11_-_99996452 0.01 ENSMUST00000107416.3
Krt36
keratin 36
chr5_+_71857261 0.00 ENSMUST00000031122.9
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr18_+_13139992 0.00 ENSMUST00000041676.3
ENSMUST00000234084.2
ENSMUST00000234565.2
Hrh4
histamine receptor H4
chr15_+_92495007 0.00 ENSMUST00000035399.10
Pdzrn4
PDZ domain containing RING finger 4
chr14_-_50479323 0.00 ENSMUST00000214152.2
Olfr731
olfactory receptor 731

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.5 1.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.5 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.3 1.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.3 0.9 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 1.0 GO:0010982 GPI anchor release(GO:0006507) regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 1.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.2 GO:2000978 negative regulation of forebrain neuron differentiation(GO:2000978)
0.1 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.5 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.4 GO:0006083 acetate metabolic process(GO:0006083)
0.1 1.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.0 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:2000054 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.5 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.6 GO:0015695 organic cation transport(GO:0015695)
0.0 1.0 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.0 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.0 0.0 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.1 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.4 GO:1990357 terminal web(GO:1990357)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 1.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.0 GO:0004630 phospholipase D activity(GO:0004630)
0.1 1.0 GO:0045340 mercury ion binding(GO:0045340)
0.1 1.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0071820 N-box binding(GO:0071820)
0.1 3.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 1.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport